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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycylsarcosine
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Accession:CHEBI:155876 term browser browse the term
Definition:A dipeptide obtained by formal condensation of the carboxy group of glycine with the amino group of sarcosine.
Synonyms:exact_synonym: glycyl-N-methylglycine
 related_synonym: 2-(2-amino-N-methylacetamido)acetic acid;   Formula=C5H10N2O3;   Gly-Sar;   InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10);   InChIKey=VYAMLSCELQQRAE-UHFFFAOYSA-N;   N-glycyl-N-methylglycine;   N-glycyl-Sar-OH;   N-glycylsarcosine;   SMILES=OC(=O)CN(C(CN)=O)C;   [(aminoacetyl)(methyl)amino]acetic acid;   glycyl-sarcosine
 xref: CAS:29816-01-1
 xref_mesh: MESH:C004194
 xref: PMID:17380260;   PMID:19201665;   PMID:23738724;   PMID:25260349;   PMID:26924013;   PMID:28594555;   PMID:29684535;   PMID:29797328;   PMID:30138575;   PMID:32024310;   PMID:32238712;   PMID:4708825;   PMID:477234;   PMID:514081;   PMID:520587;   Reaxys:1768450
 cyclic_relationship: is_tautomer_of CHEBI:155838


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glycylsarcosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a1 solute carrier family 15 member 1 multiple interactions
affects transport
increases uptake
decreases activity		 ISO
EXP		 [Zinc results in decreased activity of SLC15A1 protein] which results in decreased uptake of glycylsarcosine; benazepril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Cilazapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Fosinopril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; glycylsarcosine inhibits the reaction [SLC15A1 protein results in increased transport of Lisdexamfetamine Dimesylate]; moexipril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Perindopril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Quinapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; quinaprilat inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Ramipril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; spirapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; trandolapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]
SLC15A1 protein affects the transport of glycylsarcosine
glycylsarcosine results in decreased activity of SLC15A1 protein		 CTD PMID:14567632 PMID:18713951 PMID:20628632 PMID:21240898 PMID:21341280 More... NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions
increases uptake		 ISO
EXP		 benazepril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Enalapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Quinapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; quinaprilat inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; spirapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]
benazepril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Cilazapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Fosinopril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; moexipril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Perindopril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Quinapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; quinaprilat inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Ramipril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; spirapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; trandolapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]		 CTD PMID:18713951 PMID:33007874 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      group 19831
        organic group 18983
          amino-acid residue 11442
            peptide 11442
              oligopeptide 1349
                dipeptide 413
                  glycylsarcosine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      carboacyl group 17699
                                        univalent carboacyl group 17699
                                          carbamoyl group 17550
                                            carboxamide 17550
                                              peptide 11442
                                                oligopeptide 1349
                                                  dipeptide 413
                                                    glycylsarcosine 2
paths to the root