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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lauroyl-CoA
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Accession:CHEBI:15521 term browser browse the term
Definition:A medium-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of lauric (dodecanoic) acid.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(dodecanoylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate)
 related_synonym: C12:0-CoA;   Dodecanoyl-CoA;   Formula=C33H58N7O17P3S;   InChI=1S/C33H58N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/t22-,26-,27-,28+,32-/m1/s1;   InChIKey=YMCXGHLSVALICC-GMHMEAMDSA-N;   Lauroyl-coenzyme A;   SMILES=CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N;   coenzyme A, S-dodecanoate;   dodecanoyl-coenzyme A
 alt_id: CHEBI:14188;   CHEBI:14501;   CHEBI:25014;   CHEBI:41874;   CHEBI:6392
 xref: CAS:6244-92-4;   Chemspider:145018;   DrugBank:DB03264;   FooDB:FDB023198;   HMDB:HMDB0003571;   KEGG:C01832;   LIPID_MAPS_instance:LMFA07050340
 xref_mesh: MESH:C050466
 xref: PDBeChem:DCC;   PMID:10652339;   PMID:1263766;   PMID:15713483;   PMID:15849423;   PMID:16021622;   PMID:16665518;   PMID:21349973;   PMID:22906002;   PMID:24356978;   PMID:27815501;   PMID:30948713;   PMID:31935250;   PMID:33885999;   PMID:3778940;   PMID:627552;   PMID:7551821;   Reaxys:8033507;   UM-BBD_compID:c0567
 cyclic_relationship: is_conjugate_acid_of CHEBI:57375


show annotations for term's descendants           Sort by:
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20849
    role 20820
      biological role 20805
        antimicrobial agent 18570
          antibacterial agent 16659
            dodecanoic acid 201
              lauroyl-CoA 3
                (S)-3-hydroxylauroyl-CoA 0
                3-oxolauroyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20849
    subatomic particle 20847
      composite particle 20860
        hadron 20847
          baryon 20860
            nucleon 20847
              atomic nucleus 20847
                atom 20860
                  main group element atom 20781
                    p-block element atom 20768
                      chalcogen 20492
                        oxygen atom 20458
                          oxygen molecular entity 20446
                            hydroxides 20231
                              oxoacid 19291
                                pnictogen oxoacid 15115
                                  phosphorus oxoacid 14671
                                    phosphoric acids 13990
                                      phosphoric acid 13985
                                        phosphoric acid derivative 13902
                                          phosphate 13901
                                            organic phosphate 13901
                                              carbohydrate phosphate 1976
                                                phospho sugar 1819
                                                  aldose phosphate 1813
                                                    aldopentose phosphate 1808
                                                      ribose phosphate 1803
                                                        ribonucleotide 1763
                                                          purine ribonucleotide 1718
                                                            adenyl ribonucleotide 1311
                                                              adenosine phosphate 298
                                                                adenosine 5'-phosphate 297
                                                                  ADP 90
                                                                    3'-phosphate-adenosine-5'-diphosphate 29
                                                                      coenzyme A 29
                                                                        acyl-CoA 29
                                                                          fatty acyl-CoA 16
                                                                            saturated fatty acyl-CoA 12
                                                                              lauroyl-CoA 3
                                                                                (S)-3-hydroxylauroyl-CoA 0
                                                                                3-oxolauroyl-CoA 0
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