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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lauroyl-CoA
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Accession:CHEBI:15521 term browser browse the term
Definition:A medium-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of lauric (dodecanoic) acid.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(dodecanoylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate)
 related_synonym: C12:0-CoA;   Dodecanoyl-CoA;   Formula=C33H58N7O17P3S;   InChI=1S/C33H58N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/t22-,26-,27-,28+,32-/m1/s1;   InChIKey=YMCXGHLSVALICC-GMHMEAMDSA-N;   Lauroyl-coenzyme A;   SMILES=CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N;   coenzyme A, S-dodecanoate;   dodecanoyl-coenzyme A
 alt_id: CHEBI:14188;   CHEBI:14501;   CHEBI:25014;   CHEBI:41874;   CHEBI:6392
 xref: CAS:6244-92-4;   Chemspider:145018;   DrugBank:DB03264;   FooDB:FDB023198;   HMDB:HMDB0003571;   KEGG:C01832;   LIPID_MAPS_instance:LMFA07050340
 xref_mesh: MESH:C050466
 xref: PDBeChem:DCC;   PMID:10652339;   PMID:1263766;   PMID:15713483;   PMID:15849423;   PMID:16021622;   PMID:16665518;   PMID:21349973;   PMID:22906002;   PMID:24356978;   PMID:27815501;   PMID:30948713;   PMID:31935250;   PMID:33885999;   PMID:3778940;   PMID:627552;   PMID:7551821;   Reaxys:8033507;   UM-BBD_compID:c0567
 cyclic_relationship: is_conjugate_acid_of CHEBI:57375


show annotations for term's descendants           Sort by:
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        antimicrobial agent 18270
          antibacterial agent 16371
            dodecanoic acid 200
              lauroyl-CoA 3
                (S)-3-hydroxylauroyl-CoA 0
                3-oxolauroyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      chalcogen 19587
                        oxygen atom 19587
                          oxygen molecular entity 19587
                            hydroxides 19390
                              oxoacid 18821
                                pnictogen oxoacid 14983
                                  phosphorus oxoacid 14581
                                    phosphoric acids 13915
                                      phosphoric acid 13923
                                        phosphoric acid derivative 13828
                                          phosphate 13820
                                            organic phosphate 13820
                                              carbohydrate phosphate 1871
                                                phospho sugar 1714
                                                  aldose phosphate 1713
                                                    aldopentose phosphate 1705
                                                      ribose phosphate 1700
                                                        ribonucleotide 1662
                                                          purine ribonucleotide 1620
                                                            adenyl ribonucleotide 1306
                                                              adenosine phosphate 296
                                                                adenosine 5'-phosphate 295
                                                                  ADP 88
                                                                    3'-phosphate-adenosine-5'-diphosphate 29
                                                                      coenzyme A 29
                                                                        acyl-CoA 29
                                                                          fatty acyl-CoA 16
                                                                            saturated fatty acyl-CoA 12
                                                                              lauroyl-CoA 3
                                                                                (S)-3-hydroxylauroyl-CoA 0
                                                                                3-oxolauroyl-CoA 0
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