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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-hydroxykynurenine
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Accession:CHEBI:1547 term browser browse the term
Definition:A hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3.
Synonyms:exact_synonym: 3-(2-amino-3-hydroxybenzoyl)alanine
 related_synonym: 2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid;   3-(3-hydroxyanthraniloyl)alanine;   3-Hydroxy-DL-kynurenine;   Formula=C10H12N2O4;   InChI=1S/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16);   InChIKey=VCKPUUFAIGNJHC-UHFFFAOYSA-N;   SMILES=NC(CC(=O)c1cccc(O)c1N)C(O)=O
 xref: CAS:484-78-6;   HMDB:HMDB0000732;   KEGG:C02794
 xref_mesh: MESH:C005045
 xref: PMID:11477208;   PMID:15206726;   Reaxys:2697635


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3-hydroxykynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase multiple interactions EXP [KMO protein results in increased hydroxylation of Kynurenine] which results in increased chemical synthesis of 3-hydroxykynurenine CTD PMID:32243540 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        biochemical role 19596
          metabolite 19558
            eukaryotic metabolite 19380
              animal metabolite 19269
                mammalian metabolite 19268
                  human metabolite 18756
                    3-hydroxykynurenine 1
                      3-hydroxy-L-kynurenine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    main group molecular entity 19838
                      s-block molecular entity 19698
                        hydrogen molecular entity 19679
                          hydrides 19181
                            inorganic hydride 18192
                              pnictogen hydride 18157
                                nitrogen hydride 18070
                                  azane 17873
                                    ammonia 17898
                                      organic amino compound 17898
                                        amino acid 16074
                                          alpha-amino acid 13947
                                            non-proteinogenic alpha-amino acid 3798
                                              hydroxy-amino acid 7
                                                hydroxykynurenine 1
                                                  3-hydroxykynurenine 1
                                                    3-hydroxy-L-kynurenine 0
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