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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:protoporphyrinogen
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Accession:CHEBI:15435 term browser browse the term
Definition:A porphyrinogen that has formula C34H40N4O4.
Synonyms:related_synonym: 7,12-diethenyl-3,8,13,17-tetramethyl-5,10,15,20,22,24-hexahydroporphyrin-2,18-dipropanoic acid;   Formula=C34H40N4O4;   InChI=1S/C34H40N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,35-38H,1-2,9-16H2,3-6H3,(H,39,40)(H,41,42);   InChIKey=UHSGPDMIQQYNAX-UHFFFAOYSA-N;   Protoporphyrinogen IX;   SMILES=Cc1c2Cc3[nH]c(Cc4[nH]c(Cc5[nH]c(Cc([nH]2)c1CCC(O)=O)c(CCC(O)=O)c5C)c(C=C)c4C)c(C=C)c3C
 alt_id: CHEBI:14962;   CHEBI:26359;   CHEBI:26360;   CHEBI:8593
 xref: Beilstein:1201533;   CAS:7412-77-3;   KEGG:C01079;   KNApSAcK:C00007371
 xref_mesh: MESH:C011539
 cyclic_relationship: is_conjugate_acid_of CHEBI:57307



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protoporphyrinogen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpox coproporphyrinogen oxidase increases chemical synthesis
multiple interactions
ISO CPOX protein results in increased chemical synthesis of protoporphyrinogen
Mercury inhibits the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]; TGFB1 protein promotes the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]
CTD PMID:11248690 PMID:19339664 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO TGFB1 protein promotes the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen] CTD PMID:11248690 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          cofactor 16588
            porphyrins 372
              porphyrinogens 2
                protoporphyrinogen 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            organic molecule 19737
                              organic cyclic compound 19526
                                organic heterocyclic compound 18870
                                  organonitrogen heterocyclic compound 18174
                                    polypyrrole 696
                                      tetrapyrrole 584
                                        cyclic tetrapyrrole 455
                                          porphyrins 372
                                            porphyrinogens 2
                                              protoporphyrinogen 2
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