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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:coenzyme A
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Accession:CHEBI:15346 term browser browse the term
Definition:A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate}
 related_synonym: 3'-phosphoadenosine-(5')diphospho(4')pantatheine;   CoA;   CoA-SH;   CoASH;   Coenzym A;   Formula=C21H36N7O16P3S;   HSCoA;   InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1;   InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-N;   Koenzym A;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS;   [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate
 alt_id: CHEBI:13294;   CHEBI:13295;   CHEBI:13298;   CHEBI:23355;   CHEBI:3771;   CHEBI:41597;   CHEBI:41631;   CHEBI:741566
 xref: Beilstein:77809;   CAS:85-61-0;   DrugBank:DB01992;   KEGG:C00010;   KNApSAcK:C00007258
 xref_mesh: MESH:D003065
 xref: PDBeChem:COA;   PDBeChem:COZ;   PMID:11923312;   PMID:13025483;   PMID:15014152;   PMID:15893380;   PMID:18407920;   PMID:19666462;   PMID:20351285;   PMID:2981478;   PMID:7310833;   Wikipedia:Coenzyme_A
 cyclic_relationship: is_conjugate_acid_of CHEBI:57287


show annotations for term's descendants           Sort by:
coenzyme A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of Coenzyme A analog CTD PMID:16141203 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects binding ISO acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases abundance
affects abundance		 ISO ACLY protein results in increased abundance of Acetyl Coenzyme A
ACLY protein affects the abundance of Acetyl Coenzyme A		 CTD PMID:28077572 PMID:36933457 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G App amyloid beta precursor protein affects localization
multiple interactions
increases secretion		 ISO APP protein affects the localization of Acetyl Coenzyme A
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]
Acetyl Coenzyme A results in increased secretion of APP protein modified form		 CTD PMID:16122837 PMID:22906069 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Crat carnitine O-acetyltransferase decreases activity EXP Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein CTD PMID:8075222 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions		 ISO ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A
3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]		 CTD PMID:25440059 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Acetyl Coenzyme A CTD PMID:33179799 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] CTD PMID:16122837 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Acetyl Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] CTD PMID:30213948 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869 		JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
affects binding		 ISO [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein]
Acetyl Coenzyme A binds to NAT1 protein		 CTD PMID:20545351 PMID:22835378 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
acryloyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl-CoA hydratase, short chain 1 increases abundance ISO ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824 		JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
butyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B affects binding ISO butyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
decanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [decanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
glutaryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
hexanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
isobutyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B affects binding ISO isobutyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511 		JBrowse link
malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
methacrylyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl-CoA hydratase, short chain 1 increases abundance ISO ECHS1 gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824 		JBrowse link
myristoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbi diazepam binding inhibitor affects binding ISO S-tetradecanoyl-coenzyme A binds to DBI protein CTD PMID:17044054 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
oleoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO oleoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO oleoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO oleoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
palmitoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases metabolic processing
multiple interactions		 ISO ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A
[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]		 CTD PMID:10497882 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis EXP CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A CTD PMID:8611161 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A] CTD PMID:19854160 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] CTD PMID:16214399 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein CTD PMID:17992261 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein
Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]		 CTD PMID:11139385 PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Shbg sex hormone binding globulin decreases expression ISO Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein CTD PMID:17992261 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
stearoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO stearoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO stearoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
succinyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of succinyl-coenzyme A CTD PMID:16141203 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        biochemical role 19596
          cofactor 16592
            coenzyme 1020
              coenzyme A 29
                (1-hydroxycyclohexyl)acetyl-CoA 0
                (2,3,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 0
                (2-trans,6-cis)-dodeca-2,6-dienoyl-CoA 0
                (2E,4Z)-deca-2,4-dienoyl-CoA 0
                (3S)-citryl-CoA 0
                (3Z,6Z)-dodecadienoyl-CoA 0
                (E)-4-(trimethylammonio)but-2-enoyl-CoA 0
                (E,E)-piperonyl-CoA 0
                (R)-methylmalonyl-CoA 0
                (R)-phenyllactoyl-CoA 0
                (S)-3-hydroxyhexanoyl-CoA 0
                (S)-methylmalonyl-CoA 0
                2'-(5''-phosphoribosyl)-3'-dephospho-CoA 0
                2'-(5-triphosphoribosyl)-3'-dephospho-CoA 0
                2-amino-5-oxocyclohex-1-enecarbonyl-CoA 0
                2-benzylsuccinyl-CoA + 0
                2-furoyl-CoA + 0
                2-methylbutanoyl-CoA + 0
                3'-dephospho-CoA 0
                3,4,4-trimethylhepta-2,5-dienoyl-CoA 0
                3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA 0
                3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA 0
                3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA 0
                3-hydroxy-3-methylbutyl-CoA 0
                3-isopropenylpimeloyl-CoA 0
                3-methylbut-3-enoyl-CoA 0
                3-oxooctadecanoyl-CoA 0
                4,8,12-trimethyltridecanoyl-CoA 0
                5-hydroxythiophene-2-carbonyl-CoA 0
                6-hydroxycyclohex-1-ene-1-carbonyl-CoA 0
                6-hydroxyhex-3-enoyl-CoA + 0
                6-oxocyclohex-1-ene-1-carbonyl-CoA 0
                CoA-glutathione 0
                N-methylanthraniloyl-CoA 0
                O(3)-(phosphoribosyl dephospho-CoA)-L-serine 0
                S-alkyl-CoA + 0
                S-nitroso-coenzyme A 0
                acetyl-CoA + 11
                acryloyl-CoA 2
                acyl-CoA + 29
                alk-2-enoyl-CoA + 0
                but-2-enoyl-CoA + 0
                butyryl-CoA + 2
                cinnamoyl-CoA + 0
                cis-dodec-3-enoyl-CoA 0
                cis-geranoyl-CoA 0
                cis-tetradec-11-enoyl-CoA 0
                cis-tetradec-3-enoyl-CoA 0
                citramalyl-CoA + 0
                cyclohexa-1,4-diene-1-carbonyl-CoA 0
                cyclohexa-1,5-diene-1-carbonyl-CoA + 0
                cyclohexa-2,5-diene-1-carbonyl-CoA 0
                decanoyl-CoA + 2
                deoxycholoyl-CoA 0
                farnesoyl-CoA 0
                feruloyl-CoA + 0
                gamma-butyrobetainyl-CoA 0
                glutaryl-CoA + 2
                heptanoyl-CoA + 0
                hexanoyl-CoA + 1
                icosanoyl-CoA + 0
                indol-3-ylacetyl-CoA 0
                isobutyryl-CoA + 1
                itaconyl-CoA 0
                linoleoyl-CoA 0
                malonyl-CoA 2
                methacrylyl-CoA 2
                myristoyl-CoA + 3
                nonanoyl-CoA 0
                oleoyl-CoA 3
                palmitoyl-CoA + 9
                pent-2-enoyl-CoA + 0
                pentanoyl-CoA + 0
                phenylglyoxylyl-CoA 0
                phytanoyl-CoA + 0
                pimeloyl-CoA + 0
                propionyl-CoA + 9
                sinapoyl-CoA 0
                succinyl-CoA 1
                sulfoacetyl-CoA 0
                tetracosanoyl-CoA 0
                tetradecenoyl-CoA + 0
                thiophene-2-carbonyl-CoA 0
                trans-3-methylglutaconyl-CoA 0
                trans-4-carboxybut-2-enoyl-CoA 0
                trans-dec-2-enoyl-CoA 0
                trans-dodec-2-enoyl-CoA 0
                trans-feruloyl-CoA 0
                trans-hex-2-enoyl-CoA 0
                trans-oct-2-enoyl-CoA 0
                trans-tetradec-11-enoyl-CoA 0
                trans-tetradec-2-enoyl-CoA 0
                vinylacetyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      chalcogen 19587
                        oxygen atom 19587
                          oxygen molecular entity 19587
                            hydroxides 19390
                              oxoacid 18821
                                pnictogen oxoacid 14983
                                  phosphorus oxoacid 14581
                                    phosphoric acids 13915
                                      phosphoric acid 13923
                                        phosphoric acid derivative 13828
                                          phosphate 13820
                                            organic phosphate 13820
                                              carbohydrate phosphate 1871
                                                phospho sugar 1714
                                                  aldose phosphate 1713
                                                    aldopentose phosphate 1705
                                                      ribose phosphate 1700
                                                        ribonucleotide 1662
                                                          purine ribonucleotide 1620
                                                            adenyl ribonucleotide 1306
                                                              adenosine phosphate 296
                                                                adenosine 5'-phosphate 295
                                                                  ADP 88
                                                                    3'-phosphate-adenosine-5'-diphosphate 29
                                                                      coenzyme A 29
                                                                        (1-hydroxycyclohexyl)acetyl-CoA 0
                                                                        (2,3,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 0
                                                                        (2-trans,6-cis)-dodeca-2,6-dienoyl-CoA 0
                                                                        (2E,4Z)-deca-2,4-dienoyl-CoA 0
                                                                        (3S)-citryl-CoA 0
                                                                        (3Z,6Z)-dodecadienoyl-CoA 0
                                                                        (E)-4-(trimethylammonio)but-2-enoyl-CoA 0
                                                                        (E,E)-piperonyl-CoA 0
                                                                        (R)-methylmalonyl-CoA 0
                                                                        (R)-phenyllactoyl-CoA 0
                                                                        (S)-3-hydroxyhexanoyl-CoA 0
                                                                        (S)-methylmalonyl-CoA 0
                                                                        2'-(5''-phosphoribosyl)-3'-dephospho-CoA 0
                                                                        2'-(5-triphosphoribosyl)-3'-dephospho-CoA 0
                                                                        2-amino-5-oxocyclohex-1-enecarbonyl-CoA 0
                                                                        2-benzylsuccinyl-CoA + 0
                                                                        2-furoyl-CoA + 0
                                                                        2-methylbutanoyl-CoA + 0
                                                                        3'-dephospho-CoA 0
                                                                        3,4,4-trimethylhepta-2,5-dienoyl-CoA 0
                                                                        3,4-dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA 0
                                                                        3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA 0
                                                                        3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA 0
                                                                        3-hydroxy-3-methylbutyl-CoA 0
                                                                        3-isopropenylpimeloyl-CoA 0
                                                                        3-methylbut-3-enoyl-CoA 0
                                                                        3-oxooctadecanoyl-CoA 0
                                                                        4,8,12-trimethyltridecanoyl-CoA 0
                                                                        5-hydroxythiophene-2-carbonyl-CoA 0
                                                                        6-hydroxycyclohex-1-ene-1-carbonyl-CoA 0
                                                                        6-hydroxyhex-3-enoyl-CoA + 0
                                                                        6-oxocyclohex-1-ene-1-carbonyl-CoA 0
                                                                        CoA-glutathione 0
                                                                        N-methylanthraniloyl-CoA 0
                                                                        O(3)-(phosphoribosyl dephospho-CoA)-L-serine 0
                                                                        S-alkyl-CoA + 0
                                                                        S-nitroso-coenzyme A 0
                                                                        acetyl-CoA + 11
                                                                        acryloyl-CoA 2
                                                                        acyl-CoA + 29
                                                                        alk-2-enoyl-CoA + 0
                                                                        but-2-enoyl-CoA + 0
                                                                        butyryl-CoA + 2
                                                                        cinnamoyl-CoA + 0
                                                                        cis-dodec-3-enoyl-CoA 0
                                                                        cis-geranoyl-CoA 0
                                                                        cis-tetradec-11-enoyl-CoA 0
                                                                        cis-tetradec-3-enoyl-CoA 0
                                                                        citramalyl-CoA + 0
                                                                        cyclohexa-1,4-diene-1-carbonyl-CoA 0
                                                                        cyclohexa-1,5-diene-1-carbonyl-CoA + 0
                                                                        cyclohexa-2,5-diene-1-carbonyl-CoA 0
                                                                        decanoyl-CoA + 2
                                                                        deoxycholoyl-CoA 0
                                                                        farnesoyl-CoA 0
                                                                        feruloyl-CoA + 0
                                                                        gamma-butyrobetainyl-CoA 0
                                                                        glutaryl-CoA + 2
                                                                        heptanoyl-CoA + 0
                                                                        hexanoyl-CoA + 1
                                                                        icosanoyl-CoA + 0
                                                                        indol-3-ylacetyl-CoA 0
                                                                        isobutyryl-CoA + 1
                                                                        itaconyl-CoA 0
                                                                        linoleoyl-CoA 0
                                                                        malonyl-CoA 2
                                                                        methacrylyl-CoA 2
                                                                        myristoyl-CoA + 3
                                                                        nonanoyl-CoA 0
                                                                        oleoyl-CoA 3
                                                                        palmitoyl-CoA + 9
                                                                        pent-2-enoyl-CoA + 0
                                                                        pentanoyl-CoA + 0
                                                                        phenylglyoxylyl-CoA 0
                                                                        phytanoyl-CoA + 0
                                                                        pimeloyl-CoA + 0
                                                                        propionyl-CoA + 9
                                                                        sinapoyl-CoA 0
                                                                        succinyl-CoA 1
                                                                        sulfoacetyl-CoA 0
                                                                        tetracosanoyl-CoA 0
                                                                        tetradecenoyl-CoA + 0
                                                                        thiophene-2-carbonyl-CoA 0
                                                                        trans-3-methylglutaconyl-CoA 0
                                                                        trans-4-carboxybut-2-enoyl-CoA 0
                                                                        trans-dec-2-enoyl-CoA 0
                                                                        trans-dodec-2-enoyl-CoA 0
                                                                        trans-feruloyl-CoA 0
                                                                        trans-hex-2-enoyl-CoA 0
                                                                        trans-oct-2-enoyl-CoA 0
                                                                        trans-tetradec-11-enoyl-CoA 0
                                                                        trans-tetradec-2-enoyl-CoA 0
                                                                        vinylacetyl-CoA 0
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