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G |
Ace |
angiotensin I converting enzyme |
decreases expression |
ISO |
rebaudioside A results in decreased expression of ACE mRNA |
CTD |
PMID:31655124 |
|
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Acox1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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|
G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression |
ISO |
rebaudioside A results in increased expression of AGTR1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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|
G |
Alox5 |
arachidonate 5-lipoxygenase |
increases expression |
ISO |
rebaudioside A results in increased expression of ALOX5 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression |
ISO |
rebaudioside A results in decreased expression of BAX mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Calca |
calcitonin-related polypeptide alpha |
increases expression |
ISO |
rebaudioside A results in increased expression of CALCA mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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|
G |
Cat |
catalase |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Cav1 |
caveolin 1 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of CAV1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of CCL2 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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|
G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
decreases expression |
ISO |
rebaudioside A results in decreased expression of CFLAR mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
|
|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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|
G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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|
G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of EDN1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
increases expression |
ISO |
rebaudioside A results in increased expression of EDNRA mRNA |
CTD |
PMID:31655124 |
|
NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
F2r |
coagulation factor II (thrombin) receptor |
decreases expression |
ISO |
rebaudioside A results in decreased expression of F2R mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
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G |
Faslg |
Fas ligand |
increases expression |
ISO |
rebaudioside A results in increased expression of FASLG mRNA |
CTD |
PMID:31655124 |
|
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fgf1 |
fibroblast growth factor 1 |
increases expression |
ISO |
rebaudioside A results in increased expression of FGF1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of FLT1 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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|
G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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|
G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL10 protein] |
CTD |
PMID:30883860 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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|
G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL6 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Insr |
insulin receptor |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Itgav |
integrin subunit alpha V |
decreases expression |
ISO |
rebaudioside A results in decreased expression of ITGAV mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
decreases expression |
ISO |
rebaudioside A results in decreased expression of KIT mRNA |
CTD |
PMID:31655124 |
|
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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|
G |
Lep |
leptin |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of ACOX1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CAT mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of CPT1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of DGAT2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FOXO1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of G6PC1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of INSR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of IRS2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA]; rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of LIPC mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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|
G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP2 protein] |
CTD |
PMID:30883860 |
|
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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|
G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression multiple interactions |
ISO EXP |
rebaudioside A results in increased expression of MMP9 mRNA rebaudioside A inhibits the reaction [Thioacetamide results in increased activity of MMP9 protein] |
CTD |
PMID:30883860 PMID:31655124 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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|
G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of MTOR mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKB1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of NFKBIA mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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|
G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PCK1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pf4 |
platelet factor 4 |
increases expression |
ISO |
rebaudioside A results in increased expression of PF4 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARA mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARD mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARG mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of PPARGC1A mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of PTGS2 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of RELA protein] |
CTD |
PMID:30883860 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SCD1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Sele |
selectin E |
decreases expression |
ISO |
rebaudioside A results in decreased expression of SELE mRNA |
CTD |
PMID:31655124 |
|
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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|
G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SIRT1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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|
G |
Slc27a1 |
solute carrier family 27 member 1 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC27A1 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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|
G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SLC2A2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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|
G |
Smad7 |
SMAD family member 7 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] |
CTD |
PMID:30883860 |
|
NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
rebaudioside A affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of SOD2 mRNA] |
CTD |
PMID:25554529 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] |
CTD |
PMID:30883860 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of TNF protein] |
CTD |
PMID:30883860 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfsf10 |
TNF superfamily member 10 |
decreases expression |
ISO |
rebaudioside A results in decreased expression of TNFSF10 mRNA |
CTD |
PMID:31655124 |
|
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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