CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: benzyl cinnamate
Accession: CHEBI:146174
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Definition: The cinnamate ester derived from cinnamic acid and benzyl alcohol. Occuring in Balsam of Peru and Tolu balsam, in Sumatra and Penang benzoin, and as the main constituent of copaiba balsam, it is used in heavy oriental perfumes, as a fixative and as a flavouring agent.
Synonyms: exact_synonym: benzyl (2E)-3-phenylprop-2-enoate
related_synonym: 3-phenyl-2-propenoic acid, phenylmethyl ester; Benzyl alcohol, cinnamic ester; Formula=C16H14O2; InChI=1S/C16H14O2/c17-16(12-11-14-7-3-1-4-8-14)18-13-15-9-5-2-6-10-15/h1-12H,13H2/b12-11+; InChIKey=NGHOLYJTSCBCGC-VAWYXSNFSA-N; SMILES=C=1(C=CC=CC1)COC(/C=C/C=2C=CC=CC2)=O; benzyl (2E)-3-phenylacrylate; trans-Cinnamic acid benzyl ester
xref_mesh: MESH:C526327
xref: PMID:18037214; PMID:21126078; PMID:26398669; PMID:29454949; PMID:31901073; Wikipedia:Benzyl_cinnamate
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
benzyl cinnamate results in increased expression of AKR1C2 mRNA
CTD
PMID:20491607
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Cd86
CD86 molecule
increases expression
ISO
benzyl cinnamate results in increased expression of CD86 protein
CTD
PMID:29540657
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
benzyl cinnamate results in increased expression of CYP1A1 mRNA
CTD
PMID:20491607
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Maff
MAF bZIP transcription factor F
increases expression
ISO
benzyl cinnamate results in increased expression of MAFF mRNA
CTD
PMID:20491607
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Maoa
monoamine oxidase A
decreases activity
ISO
benzyl cinnamate results in decreased activity of MAOA protein
CTD
PMID:27270453
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
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Maob
monoamine oxidase B
decreases activity
ISO
benzyl cinnamate results in decreased activity of MAOB protein
CTD
PMID:27270453
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
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Mt1
metallothionein 1
increases expression
ISO
benzyl cinnamate results in increased expression of MT1A mRNA
CTD
PMID:20491607
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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Mt2A
metallothionein 2A
increases expression
ISO
benzyl cinnamate results in increased expression of MT2A mRNA
CTD
PMID:20491607
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
benzyl cinnamate results in increased expression of NQO1 mRNA
CTD
PMID:20491607
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Txn1
thioredoxin 1
increases expression
ISO
benzyl cinnamate results in increased expression of TXN mRNA
CTD
PMID:20491607
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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