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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methylarsonite
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Accession:CHEBI:14597 term browser browse the term
Definition:An arsenic oxoanion obtained deprotonation of both arsenite OH groups of methylarsonous acid.
Synonyms:related_synonym: Formula=CH3AsO2;   InChI=1S/CH3AsO2/c1-2(3)4/h1H3/q-2;   InChIKey=OMPSDEOAXJHSLH-UHFFFAOYSA-N;   SMILES=C[As]([O-])[O-];   [As(CH3)O2](2-)
 xref_mesh: MESH:C501996
 xref: Reaxys:11246400
 cyclic_relationship: is_conjugate_base_of CHEBI:17826



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methylarsonite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase multiple interactions
increases chemical synthesis
ISO Cysteine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; Glutathione promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite] CTD PMID:22955273 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
JBrowse link
G Gys2 glycogen synthase 2 multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in increased activity of GYS2 protein] CTD PMID:28952001 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228
JBrowse link
G Ins1 insulin 1 multiple interactions ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; methylarsonite inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Glucose results in increased secretion of INS1 protein]]; methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]; methylarsonite inhibits the reaction [Potassium Chloride results in increased secretion of INS1 protein]; Tolbutamide inhibits the reaction [methylarsonite inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31332465 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Ins2 insulin 2 multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in decreased activity of PYGL protein]; methylarsonite inhibits the reaction [INS protein results in increased activity of GYS2 protein] CTD PMID:28952001 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Pygl glycogen phosphorylase L multiple interactions ISO methylarsonite inhibits the reaction [INS protein results in decreased activity of PYGL protein] CTD PMID:28952001 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      atom 19897
        metalloid atom 15410
          arsenic atom 14699
            arsenic molecular entity 14699
              arsenic oxoanion 6355
                methylarsonite 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19836
                    p-block element atom 19836
                      chalcogen 19588
                        oxygen atom 19560
                          oxygen molecular entity 19560
                            oxide 12888
                              oxoanion 10467
                                pnictogen oxoanion 6509
                                  arsenic oxoanion 6355
                                    arsonite(2-) 5
                                      methylarsonite 5
paths to the root