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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methyl 3,4,5-trihydroxybenzoate
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Accession:CHEBI:145828 term browser browse the term
Definition:A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties.
Synonyms:related_synonym: 3,4,5-trihydroxy-benzoic acid methyl ester;   Formula=C8H8O5;   InChI=1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3;   InChIKey=FBSFWRHWHYMIOG-UHFFFAOYSA-N;   SMILES=OC1=CC(=CC(O)=C1O)C(OC)=O;   gallic acid methyl ester;   methyl gallate;   methylgallate
 xref: CAS:99-24-1;   FooDB:FDB000663;   KNApSAcK:C00030754
 xref_mesh: MESH:C052082
 xref: PMID:10346950;   PMID:12094296;   PMID:2437251;   PMID:27227459;   PMID:27592552;   PMID:28272351;   PMID:2840133;   PMID:28744880;   PMID:29116460;   PMID:29120784;   PMID:29847215;   PMID:30314293;   PMID:30886338;   PMID:31151650;   PMID:31557976;   PMID:31890180;   Reaxys:2113180;   Wikipedia:Methyl_gallate


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methyl 3,4,5-trihydroxybenzoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO methyl gallate results in increased expression of HMOX1 mRNA CTD PMID:27777014 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il10 interleukin 10 decreases expression ISO methyl gallate results in decreased expression of IL10 protein CTD PMID:32112863 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO methyl gallate results in increased expression of [IL12A protein binds to IL12B protein] CTD PMID:32112863 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO methyl gallate results in increased expression of NFE2L2 protein CTD PMID:27777014 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO methyl gallate results in increased expression of TNF protein CTD PMID:32112863 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      chemical role 19479
        antioxidant 16148
          methyl 3,4,5-trihydroxybenzoate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      aromatic carboxylic acid 12689
                                        benzoic acids 12666
                                          benzoic acid 5504
                                            hydroxybenzoic acid 4979
                                              trihydroxybenzoic acid 2750
                                                gallic acid 2733
                                                  gallate ester 2288
                                                    methyl 3,4,5-trihydroxybenzoate 6
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