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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:macrotriolide
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Accession:CHEBI:145559 term browser browse the term
Definition:A macropolylide which contains three ester linkages in one macrocyclic ring.


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verrucarin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 increases expression
affects secretion		 ISO muconomycin A results in increased expression of IL2 mRNA
muconomycin A affects the secretion of IL2 protein		 CTD PMID:8560498 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 affects secretion
increases expression		 ISO muconomycin A affects the secretion of IL4 protein
muconomycin A results in increased expression of IL4 mRNA		 CTD PMID:8560498 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 affects secretion ISO muconomycin A affects the secretion of IL5 protein CTD PMID:8560498 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 increases expression ISO muconomycin A results in increased expression of IL6 mRNA CTD PMID:8560498 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    chemical entity 19865
      atom 19865
        nonmetal atom 19787
          oxygen atom 19527
            oxygen molecular entity 19527
              organooxygen compound 19189
                polyketide 11522
                  macrolide 7531
                    macropolylide 758
                      macrotriolide 4
                        Parsonsine 0
                        diglucosyl-enterobactin 0
                        enterobactin + 0
                        monoglucosyl-enterobactin 0
                        triglucosyl-enterobactin 0
                        verrucarin A 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            heteroorganic entity 19512
                              organochalcogen compound 19273
                                organooxygen compound 19189
                                  ester 17461
                                    carboxylic ester 16750
                                      lactone 13298
                                        macrocyclic lactone 7583
                                          macrolide 7531
                                            macropolylide 758
                                              macrotriolide 4
                                                Parsonsine 0
                                                diglucosyl-enterobactin 0
                                                enterobactin + 0
                                                monoglucosyl-enterobactin 0
                                                triglucosyl-enterobactin 0
                                                verrucarin A 4
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