Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:macrodiolide
go back to main search page
Accession:CHEBI:145556 term browser browse the term
Definition:A macropolylide which contains two ester linkages in one macrocyclic ring.
Synonyms:related_synonym: macrodiolides
 xref: PMID:17446696;   PMID:29624065;   PMID:29671776;   PMID:31247219


show annotations for term's descendants           Sort by:
antimycin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBP alpha-1-microglobulin/bikunin precursor decreases uptake EXP Antimycin A results in decreased uptake of AMBP protein CTD PMID:9019736 NCBI chr 1:254,683,885...254,703,220
Ensembl chr 1:254,683,891...254,703,225 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] CTD PMID:25087994 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein; Quercetin promotes the reaction [[Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein] CTD PMID:25087994 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5152
    chemical entity 5152
      atom 5143
        nonmetal atom 5109
          oxygen atom 4979
            oxygen molecular entity 4979
              organooxygen compound 4793
                polyketide 320
                  macrolide 308
                    macropolylide 3
                      macrodiolide 3
                        ANTIMYCIN 0
                        Clonostachydiol 0
                        Lepranthin 0
                        SWINHOLIDE A 0
                        acaulide 0
                        antimycin A 3
                        antimycin A9 0
                        aplysiatoxins + 0
                        boromycin 0
                        carpaine 0
                        conglobatin 0
                        elaiophylin 0
                        fattiviracin A1 0
                        pateamine 0
                        riddelliine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5152
    subatomic particle 5143
      composite particle 5143
        hadron 5143
          baryon 5143
            nucleon 5143
              atomic nucleus 5143
                atom 5143
                  main group element atom 5116
                    p-block element atom 5113
                      carbon group element atom 5031
                        carbon atom 5030
                          organic molecular entity 5030
                            heteroorganic entity 4875
                              organochalcogen compound 4829
                                organooxygen compound 4793
                                  ester 550
                                    carboxylic ester 510
                                      lactone 381
                                        macrocyclic lactone 308
                                          macrolide 308
                                            macropolylide 3
                                              macrodiolide 3
                                                ANTIMYCIN 0
                                                Clonostachydiol 0
                                                Lepranthin 0
                                                SWINHOLIDE A 0
                                                acaulide 0
                                                antimycin A 3
                                                antimycin A9 0
                                                aplysiatoxins + 0
                                                boromycin 0
                                                carpaine 0
                                                conglobatin 0
                                                elaiophylin 0
                                                fattiviracin A1 0
                                                pateamine 0
                                                riddelliine + 0
paths to the root