macrodiolide - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	macrodiolide	go back to main search page
Accession:	CHEBI:145556	browse the term
Definition:	A macropolylide which contains two ester linkages in one macrocyclic ring.
Synonyms:	related_synonym:	macrodiolides
	xref:	PMID:17446696; PMID:29624065; PMID:29671776; PMID:31247219

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Rat (757) Mouse (755) Human (777) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (3) Green Monkey (0) Naked Mole-rat (0) All
Genes (777)

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ANTIMYCIN

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 11

decreases activity

antimycin results in decreased activity of ABCB11 protein

NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324

G

angiotensinogen

multiple interactions

antimycin inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]

NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576

G

AKT serine/threonine kinase 1

increases phosphorylation

antimycin results in increased phosphorylation of AKT1 protein

NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759

G

BCL2 like 1

increases expression

antimycin results in increased expression of BCL2L1 protein

NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989

G

caspase 3

multiple interactions

antimycin results in increased cleavage of and results in increased activity of CASP3 protein

NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062

G

mitogen-activated protein kinase 8

decreases phosphorylation

antimycin results in decreased phosphorylation of MAPK8 protein

NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360

G

mitogen-activated protein kinase 9

decreases phosphorylation

antimycin results in decreased phosphorylation of MAPK9 protein

NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099

G

NFKB inhibitor alpha

multiple interactions

antimycin inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

paired box 3

decreases expression

antimycin results in decreased expression of PAX3 mRNA

NCBI chr 2:222,199,887...222,298,998
Ensembl chr 2:222,199,887...222,298,998

G

phospholipase C gamma 1

increases phosphorylation

antimycin results in increased phosphorylation of PLCG1 protein

NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801

G

protein kinase AMP-activated catalytic subunit alpha 1

increases phosphorylation

antimycin results in increased phosphorylation of PRKAA1 protein

NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374

G

ribosomal protein S6 kinase B1

multiple interactions
decreases phosphorylation

oxophenylarsine inhibits the reaction [antimycin results in decreased phosphorylation of RPS6KB1 protein]

NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574

G

superoxide dismutase 2

decreases response to substance

SOD2 protein results in decreased susceptibility to antimycin

NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529

antimycin A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 6 (LAN blood group)

increases expression

Antimycin A results in increased expression of ABCB6 mRNA

NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994

G

abhydrolase domain containing 6, acylglycerol lipase

decreases expression

Antimycin A results in decreased expression of ABHD6 mRNA

NCBI chr 3:58,237,792...58,294,734
Ensembl chr 3:58,237,532...58,295,693

G

acyl-CoA dehydrogenase very long chain

decreases expression

Antimycin A results in decreased expression of ACADVL mRNA

NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266

G

acyl-CoA oxidase 2

increases expression

Antimycin A results in increased expression of ACOX2 mRNA

NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283

G

ADAM metallopeptidase domain 10

decreases expression

Antimycin A results in decreased expression of ADAM10 mRNA

NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791

G

adrenomedullin

increases expression

Antimycin A results in increased expression of ADM mRNA

NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397

G

apoptosis enhancing nuclease

increases expression

Antimycin A results in increased expression of AEN mRNA

NCBI chr15:88,604,683...88,632,281
Ensembl chr15:88,621,337...88,632,281

G

activator of HSP90 ATPase activity 1

increases expression

Antimycin A results in increased expression of AHSA1 mRNA

NCBI chr14:77,457,867...77,469,472
Ensembl chr14:77,457,870...77,469,472

G

aldo-keto reductase family 1 member B

decreases expression

Antimycin A results in decreased expression of AKR1B1 mRNA

NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284

G

aldo-keto reductase family 1 member B15

increases expression

Antimycin A results in increased expression of AKR1B7 mRNA

NCBI chr 7:134,549,110...134,579,869
Ensembl chr 7:134,549,110...134,579,875

G

aldo-keto reductase family 7 member A2

decreases expression

Antimycin A results in decreased expression of AKR7A2 mRNA

NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,301,991...19,312,144

G

AKT serine/threonine kinase 1

decreases activity
decreases expression
multiple interactions

Antimycin A results in decreased activity of AKT1 protein
Antimycin A results in decreased expression of AKT1 mRNA
Luteolin inhibits the reaction [Antimycin A results in decreased activity of AKT1 protein]

PMID:21466842 PMID:21782929 PMID:33512557

NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759

G

5'-aminolevulinate synthase 1

decreases expression

Antimycin A results in decreased expression of ALAS1 mRNA

NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327

G

aldehyde dehydrogenase 1 family member L2

increases expression

Antimycin A results in increased expression of ALDH1L2 mRNA

NCBI chr12:105,019,790...105,084,458
Ensembl chr12:105,019,784...105,107,643

G

aldehyde dehydrogenase 2 family member

decreases expression

Antimycin A results in decreased expression of ALDH2 mRNA

NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532

G

aldehyde dehydrogenase 7 family member A1

decreases expression

Antimycin A results in decreased expression of ALDH7A1 mRNA

NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362

G

aldolase, fructose-bisphosphate A

increases expression

Antimycin A results in increased expression of ALDOA mRNA

NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457

G

APC membrane recruitment protein 1

decreases expression

Antimycin A results in decreased expression of AMER1 mRNA

NCBI chr X:64,185,117...64,205,708
Ensembl chr X:64,185,117...64,205,708

G

angiopoietin like 6

increases expression

Antimycin A results in increased expression of ANGPTL6 mRNA

NCBI chr19:10,092,338...10,106,190
Ensembl chr19:10,092,338...10,102,678

G

ankyrin repeat domain 20 family member A13, pseudogene

decreases expression

Antimycin A results in decreased expression of ANKRD20A13P mRNA

G

anillin, actin binding protein

increases expression

Antimycin A results in increased expression of ANLN mRNA

NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791

G

acidic nuclear phosphoprotein 32 family member E

increases expression

Antimycin A results in increased expression of ANP32E mRNA

NCBI chr 1:150,218,417...150,236,112
Ensembl chr 1:150,218,417...150,236,156

G

annexin A2

increases expression

Antimycin A results in increased expression of ANXA2 mRNA

NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883

G

annexin A2 pseudogene 2

increases expression

Antimycin A results in increased expression of ANXA2P2 mRNA

NCBI chr 9:33,624,225...33,625,534
Ensembl chr 9:33,624,274...33,625,293

G

adaptor related protein complex 3 subunit mu 1

decreases expression

Antimycin A results in decreased expression of AP3M1 mRNA

NCBI chr10:74,120,255...74,150,828
Ensembl chr10:74,120,255...74,150,842

G

amyloid beta precursor like protein 1

decreases expression

Antimycin A results in decreased expression of APLP1 mRNA

NCBI chr19:35,868,574...35,879,792
Ensembl chr19:35,867,899...35,879,803

G

Rho GTPase activating protein 8

increases expression

Antimycin A results in increased expression of ARHGAP8 mRNA

NCBI chr22:44,752,575...44,862,784
Ensembl chr22:44,752,558...44,862,788

G

ARF like GTPase 4D

increases expression

Antimycin A results in increased expression of ARL4D mRNA

NCBI chr17:43,398,993...43,401,137
Ensembl chr17:43,398,993...43,401,137

G

arrestin domain containing 4

decreases expression

Antimycin A results in decreased expression of ARRDC4 mRNA

NCBI chr15:97,960,703...97,973,833
Ensembl chr15:97,960,703...97,973,833

G

activating signal cointegrator 1 complex subunit 3

increases expression

Antimycin A results in increased expression of ASCC3 mRNA

NCBI chr 6:100,508,194...100,881,329
Ensembl chr 6:100,508,194...100,881,372

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

Antimycin A results in increased expression of ASNS mRNA

NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542

G

argininosuccinate synthase 1

increases expression

Antimycin A results in increased expression of ASS1 mRNA

NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274

G

activating transcription factor 3

increases expression

Antimycin A results in increased expression of ATF3 mRNA

NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777

G

activating transcription factor 4

increases expression

Antimycin A results in increased expression of ATF4 mRNA

NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686

G

activating transcription factor 5

increases expression

Antimycin A results in increased expression of ATF5 mRNA

NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935

G

autophagy related 13

multiple interactions

Antimycin A promotes the reaction [ATG13 protein results in increased expression of ULK1 protein]; ATG13 protein promotes the reaction [Antimycin A results in increased expression of ULK1 protein]

NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818

G

ATM serine/threonine kinase

decreases expression

Antimycin A results in decreased expression of ATM mRNA

NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102

G

ATM interactor

decreases expression

Antimycin A results in decreased expression of ATMIN mRNA

NCBI chr16:81,035,842...81,047,350
Ensembl chr16:81,035,842...81,047,350

G

ATPase phospholipid transporting 11B (putative)

decreases expression

Antimycin A results in decreased expression of ATP11B mRNA

NCBI chr 3:182,793,504...182,921,629
Ensembl chr 3:182,793,503...182,923,011

G

ATPase phospholipid transporting 11C

decreases expression

Antimycin A results in decreased expression of ATP11C mRNA

NCBI chr X:139,726,348...139,936,903
Ensembl chr X:139,726,346...139,945,276

G

ATP synthase F1 subunit gamma

decreases expression

Antimycin A results in decreased expression of ATP5F1C mRNA

NCBI chr10:7,788,177...7,807,801
Ensembl chr10:7,788,147...7,807,815

G

ATPase H+ transporting V0 subunit e1

decreases expression

Antimycin A results in decreased expression of ATP6V0E1 mRNA

NCBI chr 5:172,983,771...173,035,445
Ensembl chr 5:172,983,771...173,035,445

G

ATPase H+ transporting V1 subunit B2

decreases expression

Antimycin A results in decreased expression of ATP6V1B2 mRNA

NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,230,399

G

ATPase H+ transporting V1 subunit H

multiple interactions

[PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA

NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558

G

ATRX chromatin remodeler

increases expression

Antimycin A results in increased expression of ATRX mRNA

NCBI chr X:77,504,880...77,786,216
Ensembl chr X:77,504,880...77,786,233

G

aurora kinase B

increases expression

Antimycin A results in increased expression of AURKB mRNA

NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600

G

beta-2-microglobulin

increases expression

Antimycin A results in increased expression of B2M mRNA

NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851

G

beta-1,3-galactosyltransferase 6

decreases expression

Antimycin A results in decreased expression of B3GALT6 mRNA

NCBI chr 1:1,232,237...1,235,041
Ensembl chr 1:1,232,237...1,235,041

G

BAG cochaperone 3

increases expression

Antimycin A results in increased expression of BAG3 mRNA

NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819

G

BMP and activin membrane bound inhibitor

increases expression

Antimycin A results in increased expression of BAMBI mRNA

NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932

G

barrier to autointegration nuclear assembly factor 1

increases expression

Antimycin A results in increased expression of BANF1 mRNA

NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

[FOXO1 protein co-treated with FOXO4 protein co-treated with FOXO3 protein] affects the reaction [Resveratrol inhibits the reaction [Antimycin A results in increased expression of BAX protein]]; Resveratrol inhibits the reaction [Antimycin A results in increased expression of BAX protein]
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of BAX mRNA]

PMID:24040102 PMID:33512557 PMID:35430258

NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798

G

BCL2 apoptosis regulator

decreases response to substance
multiple interactions

BCL2 protein results in decreased susceptibility to Antimycin A
PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to Antimycin A]

NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128

G

BCL2 like 13

decreases expression

Antimycin A results in decreased expression of BCL2L13 mRNA

NCBI chr22:17,628,877...17,730,855
Ensembl chr22:17,628,855...17,730,855

G

BAF chromatin remodeling complex subunit BCL7B

decreases expression

Antimycin A results in decreased expression of BCL7B mRNA

NCBI chr 7:73,536,356...73,557,690
Ensembl chr 7:73,536,356...73,557,690

G

bone gamma-carboxyglutamate protein

increases expression
multiple interactions

Antimycin A results in increased expression of BGLAP protein
sciadopitysin inhibits the reaction [Antimycin A results in increased expression of BGLAP protein]

NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317

G

BH3 interacting domain death agonist

decreases expression

Antimycin A results in decreased expression of BID mRNA

NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770

G

baculoviral IAP repeat containing 5

increases expression

Antimycin A results in increased expression of BIRC5 mRNA

NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636

G

Bcl2 modifying factor

decreases expression

Antimycin A results in decreased expression of BMF mRNA

NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892

G

BCL2 interacting protein 1

increases expression

Antimycin A results in increased expression of BNIP1 mRNA

NCBI chr 5:173,144,531...173,164,387
Ensembl chr 5:173,144,442...173,164,387

G

BCL2 interacting protein 3

increases expression

Antimycin A results in increased expression of BNIP3 mRNA

NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967

G

biphenyl hydrolase like

decreases expression

Antimycin A results in decreased expression of BPHL mRNA

NCBI chr 6:3,118,376...3,153,578
Ensembl chr 6:3,118,374...3,153,599

G

bromodomain containing 3

decreases expression

Antimycin A results in decreased expression of BRD3 mRNA

NCBI chr 9:134,030,305...134,068,548
Ensembl chr 9:134,030,305...134,068,535

G

BSCL2 lipid droplet biogenesis associated, seipin

decreases expression

Antimycin A results in decreased expression of BSCL2 mRNA

NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845

G

BTG anti-proliferation factor 2

increases expression

Antimycin A results in increased expression of BTG2 mRNA

NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602

G

BTG anti-proliferation factor 3

increases expression

Antimycin A results in increased expression of BTG3 mRNA

NCBI chr21:17,593,653...17,612,901
Ensembl chr21:17,593,653...17,612,945

G

BUB1 mitotic checkpoint serine/threonine kinase

increases expression

Antimycin A results in increased expression of BUB1 mRNA

NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063

G

basic leucine zipper and W2 domains 2

increases expression

Antimycin A results in increased expression of BZW2 mRNA

NCBI chr 7:16,646,181...16,706,517
Ensembl chr 7:16,646,131...16,706,523

G

C1D nuclear receptor corepressor

increases expression

Antimycin A results in increased expression of C1D mRNA

NCBI chr 2:68,041,130...68,063,004
Ensembl chr 2:68,041,130...68,110,948

G

C2 calcium dependent domain containing 5

decreases expression

Antimycin A results in decreased expression of C2CD5 mRNA

NCBI chr12:22,448,583...22,544,542
Ensembl chr12:22,448,583...22,544,546

G

carbonic anhydrase 6

increases expression

Antimycin A results in increased expression of CAR6 mRNA

NCBI chr 1:8,945,868...8,975,092
Ensembl chr 1:8,945,867...8,975,092

G

calmodulin 1

decreases expression

Antimycin A results in decreased expression of CALM1 mRNA

NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268

G

calcium/calmodulin dependent protein kinase II beta

decreases expression

Antimycin A results in decreased expression of CAMK2B mRNA

NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577

G

calcyphosine

decreases expression

Antimycin A results in decreased expression of CAPS mRNA

NCBI chr19:5,914,254...5,916,211
Ensembl chr19:5,912,339...5,916,211

G

cysteinyl-tRNA synthetase 1

increases expression

Antimycin A results in increased expression of CARS1 mRNA

NCBI chr11:3,000,929...3,057,423
Ensembl chr11:3,000,922...3,057,613

G

caspase 1

increases activity

Antimycin A results in increased activity of CASP1 protein

NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250

G

caspase 3

increases activity
increases expression
multiple interactions
increases cleavage

Antimycin A results in increased activity of CASP3 protein
Antimycin A results in increased expression of CASP3 mRNA
[chromium hexavalent ion co-treated with Antimycin A] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [[chromium hexavalent ion co-treated with Antimycin A] results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Antimycin A results in increased activity of CASP3 protein]
NAD inhibits the reaction [Antimycin A results in increased cleavage of CASP3 protein]; Niacinamide promotes the reaction [Antimycin A results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Antimycin A results in increased cleavage of CASP3 protein]; splitomicin promotes the reaction [Antimycin A results in increased cleavage of CASP3 protein]

PMID:11078377 PMID:24040102 PMID:24732427 PMID:32662599 PMID:35430258

NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062

G

caspase 8

increases cleavage
multiple interactions

Antimycin A results in increased cleavage of CASP8 protein
Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP8 protein]

NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836

G

caspase 9

multiple interactions
decreases expression
increases cleavage

Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP9 protein]
Antimycin A results in decreased expression of CASP9 mRNA

PMID:32662599 PMID:33512557

NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534

G

calpastatin

decreases expression

Antimycin A results in decreased expression of CAST mRNA

NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595

G

catalase

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CAT mRNA]

NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060

G

carbonyl reductase 1

decreases expression

Antimycin A results in decreased expression of CBR1 mRNA

NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166

G

chromobox 4

increases expression

Antimycin A results in increased expression of CBX4 mRNA

NCBI chr17:79,833,156...79,839,440
Ensembl chr17:79,833,156...79,839,440

G

C-C motif chemokine ligand 15

decreases expression

Antimycin A results in decreased expression of CCL15 mRNA

NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553

G

C-C motif chemokine ligand 2

decreases expression

Antimycin A results in decreased expression of CCL2 protein

NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208

G

C-C motif chemokine ligand 3

decreases expression

Antimycin A results in decreased expression of CCL3 protein

NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169

G

C-C motif chemokine ligand 4

decreases expression

Antimycin A results in decreased expression of CCL4 protein

NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621

G

C-C motif chemokine ligand 5

decreases expression

Antimycin A results in decreased expression of CCL5 protein

NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793

G

cellular communication network factor 1

increases expression

Antimycin A results in increased expression of CCN1 mRNA

NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589

G

cellular communication network factor 2

increases expression

Antimycin A results in increased expression of CCN2 mRNA

NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372

G

cyclin A2

multiple interactions
increases expression
decreases expression

Antimycin A inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]
Antimycin A results in increased expression of CCNA2 mRNA
Antimycin A results in decreased expression of CCNA2 mRNA; Antimycin A results in decreased expression of CCNA2 protein

PMID:12730239 PMID:33512557

NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883

G

cyclin B1

decreases expression
increases expression
multiple interactions

Antimycin A results in decreased expression of CCNB1 mRNA; Antimycin A results in decreased expression of CCNB1 protein
Antimycin A results in increased expression of CCNB1 mRNA
Antimycin A inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]

PMID:12730239 PMID:33512557

NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245

G

cyclin B2

increases expression

Antimycin A results in increased expression of CCNB2 mRNA

NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045

G

cyclin D2

increases expression

Antimycin A results in increased expression of CCND2 mRNA

NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353

G

cyclin G1

increases expression

Antimycin A results in increased expression of CCNG1 mRNA

NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199

G

cyclin H

increases expression

Antimycin A results in increased expression of CCNH mRNA

NCBI chr 5:87,311,471...87,412,930
Ensembl chr 5:87,318,416...87,413,029

G

CD14 molecule

increases expression

Antimycin A results in increased expression of CD14 mRNA

NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700

G

CD24 molecule

decreases expression

Antimycin A results in decreased expression of CD24 mRNA

NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627

G

CD34 molecule

decreases expression

Antimycin A results in decreased expression of CD34 mRNA

NCBI chr 1:207,880,972...207,911,125
Ensembl chr 1:207,880,972...207,911,402

G

CD38 molecule

increases expression

Antimycin A results in increased expression of CD38 mRNA

NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232

G

CD55 molecule (Cromer blood group)

decreases expression

Antimycin A results in decreased expression of CD55 mRNA

NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804

G

CD68 molecule

increases expression

Antimycin A results in increased expression of CD68 mRNA

NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111

G

cell division cycle 6

increases expression
decreases expression

Antimycin A results in increased expression of CDC6 mRNA
Antimycin A results in decreased expression of CDC6 mRNA

PMID:33512557 PMID:34642769

NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657

G

cell division cycle associated 3

increases expression

Antimycin A results in increased expression of CDCA3 mRNA

NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292

G

cell division cycle associated 5

increases expression

Antimycin A results in increased expression of CDCA5 mRNA

NCBI chr11:65,061,093...65,084,040
Ensembl chr11:65,066,300...65,084,164

G

cell division cycle associated 8

increases expression

Antimycin A results in increased expression of CDCA8 mRNA

NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719

G

cadherin 10

decreases expression

Antimycin A results in decreased expression of CDH10 mRNA

NCBI chr 5:24,487,100...24,644,978
Ensembl chr 5:24,487,100...24,644,978

G

cadherin 2

decreases expression

Antimycin A results in decreased expression of CDH2 mRNA

NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946

G

cyclin dependent kinase 1

increases expression

Antimycin A results in increased expression of CDK1 mRNA

NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852

G

cyclin dependent kinase 5

decreases expression

Antimycin A results in decreased expression of CDK5 mRNA

NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897

G

cyclin dependent kinase 5 regulatory subunit 1

decreases expression

Antimycin A results in decreased expression of CDK5R1 mRNA

NCBI chr17:32,486,993...32,491,253
Ensembl chr17:32,486,993...32,491,253

G

cyclin dependent kinase inhibitor 3

increases expression

Antimycin A results in increased expression of CDKN3 mRNA

NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218

G

chromatin licensing and DNA replication factor 1

increases expression

Antimycin A results in increased expression of CDT1 mRNA

NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258

G

CCAAT enhancer binding protein alpha

increases expression

Antimycin A results in increased expression of CEBPA mRNA

NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534

G

CCAAT enhancer binding protein beta

increases expression

Antimycin A results in increased expression of CEBPB mRNA

NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690

G

carboxyl ester lipase

decreases expression

Antimycin A results in decreased expression of CEL mRNA

NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861

G

cell migration inducing hyaluronidase 2

decreases expression

Antimycin A results in decreased expression of CEMIP2 mRNA

NCBI chr 9:71,683,366...71,769,466
Ensembl chr 9:71,683,366...71,816,690

G

centromere protein F

increases expression

Antimycin A results in increased expression of CENPF mRNA

NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574

G

centromere protein U

increases expression

Antimycin A results in increased expression of CENPU mRNA

NCBI chr 4:184,694,085...184,734,096
Ensembl chr 4:184,694,085...184,734,130

G

centromere protein W

increases expression

Antimycin A results in increased expression of CENPW mRNA

NCBI chr 6:126,340,115...126,483,320
Ensembl chr 6:126,340,115...126,348,875

G

centrosomal protein 55

increases expression

Antimycin A results in increased expression of CEP55 mRNA

NCBI chr10:93,496,612...93,529,092
Ensembl chr10:93,496,612...93,529,092

G

centrosomal protein 57

decreases expression

Antimycin A results in decreased expression of CEP57 mRNA

NCBI chr11:95,790,498...95,832,693
Ensembl chr11:95,789,965...95,832,693

G

centrin 3

decreases expression

Antimycin A results in decreased expression of CETN3 mRNA

NCBI chr 5:90,392,257...90,409,756
Ensembl chr 5:90,392,257...90,409,766

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

increases expression

Antimycin A results in increased expression of CHAC1 mRNA

NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

Antimycin A results in increased expression of CHCHD10 mRNA

NCBI chr22:23,765,834...23,767,972
Ensembl chr22:23,765,834...23,767,972

G

checkpoint kinase 1

increases expression

Antimycin A results in increased expression of CHEK1 mRNA

NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255

G

charged multivesicular body protein 4A

decreases expression

Antimycin A results in decreased expression of CHMP4A mRNA

NCBI chr14:24,209,615...24,213,488
Ensembl chr14:24,209,615...24,213,830

G

charged multivesicular body protein 6

decreases expression

Antimycin A results in decreased expression of CHMP6 mRNA

NCBI chr17:80,991,841...81,000,133
Ensembl chr17:80,991,598...81,009,517

G

cholinergic receptor nicotinic beta 2 subunit

decreases expression

Antimycin A results in decreased expression of CHRNB2 mRNA

NCBI chr 1:154,567,778...154,580,013
Ensembl chr 1:154,567,778...154,580,013

G

cytosolic iron-sulfur assembly component 2A

decreases expression

Antimycin A results in decreased expression of CIAO2A mRNA

NCBI chr15:64,072,565...64,093,838
Ensembl chr15:64,072,565...64,094,262

G

CDC28 protein kinase regulatory subunit 1B

increases expression

Antimycin A results in increased expression of CKS1B mRNA

NCBI chr 1:154,974,681...154,979,251
Ensembl chr 1:154,974,653...154,979,251

G

CDC28 protein kinase regulatory subunit 2

increases expression

Antimycin A results in increased expression of CKS2 mRNA

NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703

G

chloride intracellular channel 4

increases expression

Antimycin A results in increased expression of CLIC4 mRNA

NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321

G

calponin 3

increases expression

Antimycin A results in increased expression of CNN3 mRNA

NCBI chr 1:94,896,957...94,927,110
Ensembl chr 1:94,896,949...94,927,223

G

contactin 1

increases expression

Antimycin A results in increased expression of CNTN1 mRNA

NCBI chr12:40,692,439...41,072,415
Ensembl chr12:40,692,439...41,072,415

G

cytochrome c oxidase assembly factor 6

increases expression

Antimycin A results in increased expression of COA6 mRNA

NCBI chr 1:234,373,456...234,385,080
Ensembl chr 1:234,373,456...234,385,080

G

component of oligomeric golgi complex 2

decreases expression

Antimycin A results in decreased expression of COG2 mRNA

NCBI chr 1:230,642,481...230,693,982
Ensembl chr 1:230,642,481...230,693,982

G

collagen type XVI alpha 1 chain

decreases expression
increases expression

Antimycin A results in decreased expression of COL16A1 mRNA
Antimycin A results in increased expression of COL16A1 mRNA

PMID:19304788 PMID:33512557

NCBI chr 1:31,652,263...31,704,017
Ensembl chr 1:31,652,263...31,704,319

G

collagen type I alpha 1 chain

increases expression

Antimycin A results in increased expression of COL1A1 mRNA

NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632

G

collagen type IV alpha 1 chain

increases expression

Antimycin A results in increased expression of COL4A1 mRNA

NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202

G

collagen type IV alpha 2 chain

increases expression

Antimycin A results in increased expression of COL4A2 mRNA

NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209

G

COP9 signalosome subunit 5

decreases expression

Antimycin A results in decreased expression of COPS5 mRNA

NCBI chr 8:67,043,079...67,062,133
Ensembl chr 8:67,043,079...67,083,783

G

cytochrome c oxidase subunit 6A2

increases expression

Antimycin A results in increased expression of COX6A2 mRNA

NCBI chr16:31,427,731...31,428,360
Ensembl chr16:31,427,731...31,428,360

G

ceruloplasmin

increases degradation
decreases expression

Antimycin A results in increased degradation of CP mRNA
Antimycin A results in decreased expression of CP mRNA; Antimycin A results in decreased expression of CP protein

NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829

G

copine 3

decreases expression

Antimycin A results in decreased expression of CPNE3 mRNA

NCBI chr 8:86,514,435...86,561,498
Ensembl chr 8:86,514,435...86,561,498

G

cramped chromatin regulator homolog 1

decreases expression

Antimycin A results in decreased expression of CRAMP1 mRNA

NCBI chr16:1,612,360...1,677,908
Ensembl chr16:1,612,337...1,677,908

G

cAMP responsive element binding protein 1

decreases phosphorylation
multiple interactions

Antimycin A results in decreased phosphorylation of CREB1 protein
23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in decreased phosphorylation of CREB1 protein]; acetovanillone inhibits the reaction [Antimycin A results in decreased phosphorylation of CREB1 protein]

PMID:21538410 PMID:22180388

NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988

G

CREB3 regulatory factor

increases expression

Antimycin A results in increased expression of CREBRF mRNA

NCBI chr 5:173,056,352...173,139,284
Ensembl chr 5:173,056,352...173,139,284

G

cellular repressor of E1A stimulated genes 1

increases expression

Antimycin A results in increased expression of CREG1 mRNA

NCBI chr 1:167,541,013...167,553,762
Ensembl chr 1:167,529,117...167,553,805

G

CRK proto-oncogene, adaptor protein

decreases expression

Antimycin A results in decreased expression of CRK mRNA

NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162

G

casein kinase 1 delta

decreases expression

Antimycin A results in decreased expression of CSNK1D mRNA

NCBI chr17:82,239,019...82,273,750
Ensembl chr17:82,239,023...82,273,700

G

cysteine and serine rich nuclear protein 1

increases expression

Antimycin A results in increased expression of CSRNP1 mRNA

NCBI chr 3:39,141,855...39,154,641
Ensembl chr 3:39,141,855...39,154,562

G

cystathionine gamma-lyase

increases expression

Antimycin A results in increased expression of CTH mRNA

NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851

G

catenin alpha like 1

increases expression

Antimycin A results in increased expression of CTNNAL1 mRNA

NCBI chr 9:108,942,577...109,013,499
Ensembl chr 9:108,942,569...109,013,522

G

CTP synthase 1

decreases expression

Antimycin A results in decreased expression of CTPS1 mRNA

NCBI chr 1:40,979,696...41,012,565
Ensembl chr 1:40,979,300...41,012,565

G

cathepsin L

increases expression

Antimycin A results in increased expression of CTSL mRNA

NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469

G

cortactin

decreases expression

Antimycin A results in decreased expression of CTTN mRNA

NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584

G

C-X-C motif chemokine ligand 1

multiple interactions

Antimycin A inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]

NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308

G

C-X-C motif chemokine ligand 8

increases expression
decreases expression
multiple interactions

Antimycin A results in increased expression of CXCL8 mRNA; Antimycin A results in increased expression of CXCL8 protein
Antimycin A results in decreased expression of CXCL8 protein
Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Antimycin A inhibits the reaction [acetylleucyl-leucyl-norleucinal results in increased expression of CXCL8 mRNA]; Antimycin A inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Antimycin A inhibits the reaction [lactacystin results in increased expression of CXCL8 mRNA]; Antimycin A inhibits the reaction [MG 262 results in increased expression of CXCL8 mRNA]; Antimycin A promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Antimycin A promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; Antimycin A promotes the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Antimycin A promotes the reaction [TNF protein results in increased expression of CXCL8 protein]; BAY 11-7085 inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Resveratrol inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]

PMID:12208513 PMID:20116850 PMID:22549761

NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716

G

C-X-C motif chemokine receptor 4

decreases expression

Antimycin A results in decreased expression of CXCR4 mRNA

NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177

G

cytochrome c, somatic

affects localization
multiple interactions

Antimycin A affects the localization of CYCS protein
glabridin inhibits the reaction [Antimycin A affects the localization of CYCS protein]

NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260

G

cytochrome P450 family 3 subfamily A member 5

increases expression

Antimycin A results in increased expression of CYP3A5 mRNA

NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996

G

dishevelled associated activator of morphogenesis 1

decreases expression

Antimycin A results in decreased expression of DAAM1 mRNA

NCBI chr14:59,188,667...59,371,405
Ensembl chr14:59,188,646...59,371,405

G

dystroglycan 1

decreases expression

Antimycin A results in decreased expression of DAG1 mRNA

NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618

G

death domain associated protein

decreases expression

Antimycin A results in decreased expression of DAXX mRNA

NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016

G

dCMP deaminase

decreases expression

Antimycin A results in decreased expression of DCTD mRNA

NCBI chr 4:182,890,091...182,917,611
Ensembl chr 4:182,890,060...182,917,936

G

doublecortin

decreases expression

Antimycin A results in decreased expression of DCX mRNA

NCBI chr X:111,293,779...111,412,192
Ensembl chr X:111,293,779...111,412,429

G

dopa decarboxylase

decreases expression

Antimycin A results in decreased expression of DDC mRNA

NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405

G

DNA damage inducible transcript 3

increases expression

Antimycin A results in increased expression of DDIT3 protein
Antimycin A results in increased expression of DDIT3 mRNA

PMID:19304788 PMID:21337367 PMID:33512557

NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737

G

DNA damage inducible transcript 4

increases expression

Antimycin A results in increased expression of DDIT4 mRNA

NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036

G

DExD/H-box helicase 60

decreases expression

Antimycin A results in decreased expression of DDX60 mRNA

NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883

G

DEK proto-oncogene

increases expression

Antimycin A results in increased expression of DEK mRNA

NCBI chr 6:18,223,860...18,264,530
Ensembl chr 6:18,223,860...18,264,548

G

DEP domain containing 1B

increases expression

Antimycin A results in increased expression of DEPDC1B mRNA

NCBI chr 5:60,596,912...60,700,166
Ensembl chr 5:60,596,912...60,700,190

G

DNA fragmentation factor subunit beta

decreases expression

Antimycin A results in decreased expression of DFFB mRNA

NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429

G

DLG associated protein 5

increases expression

Antimycin A results in increased expression of DLGAP5 mRNA

NCBI chr14:55,148,135...55,191,585
Ensembl chr14:55,148,112...55,191,608

G

delta like canonical Notch ligand 1

increases expression

Antimycin A results in increased expression of DLL1 mRNA

NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression

Antimycin A results in increased expression of DNAJB6 mRNA

NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439

G

dopamine receptor D2

decreases expression

Antimycin A results in decreased expression of DRD2 mRNA

NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691

G

dual specificity phosphatase 1

increases expression

Antimycin A results in increased expression of DUSP1 mRNA

NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195

G

dual specificity phosphatase 14

increases expression

Antimycin A results in increased expression of DUSP14 mRNA

NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501

G

dual specificity phosphatase 4

increases expression

Antimycin A results in increased expression of DUSP4 mRNA

NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684

G

dynein light chain Tctex-type 3

decreases expression

Antimycin A results in decreased expression of DYNLT3 mRNA

NCBI chr X:37,838,836...37,847,571
Ensembl chr X:37,836,757...37,847,571

G

E2F transcription factor 7

decreases expression

Antimycin A results in decreased expression of E2F7 mRNA

NCBI chr12:77,021,251...77,065,569
Ensembl chr12:77,021,248...77,065,569

G

ELL associated factor 2

decreases expression

Antimycin A results in decreased expression of EAF2 mRNA

NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526

G

EBNA1 binding protein 2

decreases expression

Antimycin A results in decreased expression of EBNA1BP2 mRNA

NCBI chr 1:43,164,174...43,172,570
Ensembl chr 1:43,164,175...43,270,936

G

enoyl-CoA delta isomerase 1

decreases expression

Antimycin A results in decreased expression of ECI1 mRNA

NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300

G

early growth response 1

increases expression

Antimycin A results in increased expression of EGR1 mRNA

NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303

G

eukaryotic translation initiation factor 1A X-linked

increases expression

Antimycin A results in increased expression of EIF1AX mRNA

NCBI chr X:20,124,525...20,141,838
Ensembl chr X:20,124,525...20,141,838

G

eukaryotic translation initiation factor 3 subunit E

decreases expression

Antimycin A results in decreased expression of EIF3E mRNA

NCBI chr 8:108,201,216...108,248,717
Ensembl chr 8:108,162,787...108,443,496

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

Antimycin A results in increased expression of EIF4EBP1 mRNA

NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365

G

eukaryotic translation initiation factor 6

increases expression

Antimycin A results in increased expression of EIF6 mRNA

NCBI chr20:35,278,906...35,284,772
Ensembl chr20:35,278,907...35,284,985

G

ELAV like RNA binding protein 1

decreases localization
decreases expression
multiple interactions

Antimycin A results in decreased localization of ELAVL1 protein
Antimycin A results in decreased expression of ELAVL1 mRNA
Antimycin A inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]; Antimycin A inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]

PMID:12730239 PMID:33512557

NCBI chr19:7,958,573...8,005,641
Ensembl chr19:7,958,573...8,005,659

G

ELAV like RNA binding protein 3

decreases expression

Antimycin A results in decreased expression of ELAVL3 mRNA

NCBI chr19:11,451,326...11,481,046
Ensembl chr19:11,451,326...11,481,046

G

ELMO domain containing 1

decreases expression

Antimycin A results in decreased expression of ELMOD1 mRNA

NCBI chr11:107,591,147...107,666,779
Ensembl chr11:107,591,091...107,666,779

G

EMG1 N1-specific pseudouridine methyltransferase

increases expression

Antimycin A results in increased expression of EMG1 mRNA

NCBI chr12:6,970,913...6,997,428
Ensembl chr12:6,970,913...6,979,936

G

ectonucleoside triphosphate diphosphohydrolase 2

increases expression

Antimycin A results in increased expression of ENTPD2 mRNA

NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061

G

E1A binding protein p300

decreases expression

Antimycin A results in decreased expression of EP300 mRNA

NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077

G

endothelial PAS domain protein 1

multiple interactions

Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]

NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697

G

EPH receptor A3

decreases expression

Antimycin A results in decreased expression of EPHA3 mRNA

NCBI chr 3:89,107,621...89,482,134
Ensembl chr 3:89,107,621...89,482,134

G

EPH receptor B2

decreases expression

Antimycin A results in decreased expression of EPHB2 mRNA

NCBI chr 1:22,710,838...22,921,500
Ensembl chr 1:22,710,839...22,921,500

G

erb-b2 receptor tyrosine kinase 3

increases expression

Antimycin A results in increased expression of ERBB3 mRNA

NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505

G

endoplasmic reticulum oxidoreductase 1 alpha

increases expression

Antimycin A results in increased expression of ERO1A mRNA

NCBI chr14:52,639,915...52,695,558
Ensembl chr14:52,639,915...52,695,900

G

ETS proto-oncogene 1, transcription factor

increases expression

Antimycin A results in increased expression of ETS1 mRNA

NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558

G

ETS variant transcription factor 1

decreases expression

Antimycin A results in decreased expression of ETV1 mRNA

NCBI chr 7:13,891,229...13,991,425
Ensembl chr 7:13,891,229...13,991,425

G

Enah/Vasp-like

decreases expression

Antimycin A results in decreased expression of EVL mRNA

NCBI chr14:99,971,422...100,144,236
Ensembl chr14:99,971,449...100,144,236

G

exosome component 8

increases expression

Antimycin A results in increased expression of EXOSC8 mRNA

NCBI chr13:37,000,786...37,009,614
Ensembl chr13:36,998,816...37,025,881

G

family with sequence similarity 174 member A

decreases expression

Antimycin A results in decreased expression of FAM174A mRNA

NCBI chr 5:100,535,374...100,586,741
Ensembl chr 5:100,535,338...100,586,741

G

family with sequence similarity 217 member B

increases expression

Antimycin A results in increased expression of FAM217B mRNA

NCBI chr20:59,933,779...59,948,680
Ensembl chr20:59,933,764...59,948,680

G

family with sequence similarity 72 member A

increases expression

Antimycin A results in increased expression of FAM72A mRNA

NCBI chr 1:206,186,179...206,205,773
Ensembl chr 1:206,186,179...206,204,414

G

family with sequence similarity 72 member C

increases expression

Antimycin A results in increased expression of FAM72C mRNA

NCBI chr 1:143,955,287...143,973,564
Ensembl chr 1:143,955,287...143,971,986

G

family with sequence similarity 83 member D

increases expression

Antimycin A results in increased expression of FAM83D mRNA

NCBI chr20:38,926,417...38,953,106
Ensembl chr20:38,926,312...38,953,106

G

Fas cell surface death receptor

decreases expression
increases expression

Antimycin A results in decreased expression of FAS mRNA
Antimycin A results in increased expression of FAS mRNA

PMID:8902626 PMID:33512557

NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605

G

fatty acid synthase

decreases expression

Antimycin A results in decreased expression of FASN mRNA

NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294

G

fasciculation and elongation protein zeta 2

decreases expression

Antimycin A results in decreased expression of FEZ2 mRNA

NCBI chr 2:36,552,258...36,598,168
Ensembl chr 2:36,531,805...36,646,087

G

fibroblast growth factor 1

decreases expression

Antimycin A results in decreased expression of FGF1 mRNA

NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070

G

fibroblast growth factor 2

increases expression

Antimycin A results in increased expression of FGF2 mRNA

NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236

G

FIG4 phosphoinositide 5-phosphatase

decreases expression

Antimycin A results in decreased expression of FIG4 mRNA

NCBI chr 6:109,691,296...109,825,426
Ensembl chr 6:109,690,609...109,878,098

G

FKBP prolyl isomerase 4

increases expression

Antimycin A results in increased expression of FKBP4 mRNA

NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423

G

FKBP prolyl isomerase 5

increases expression

Antimycin A results in increased expression of FKBP5 mRNA

NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583

G

filamin A

increases expression

Antimycin A results in increased expression of FLNA mRNA

NCBI chr X:154,348,531...154,374,634
Ensembl chr X:154,348,524...154,374,634

G

fibronectin leucine rich transmembrane protein 3

increases expression

Antimycin A results in increased expression of FLRT3 mRNA

NCBI chr20:14,322,985...14,337,612
Ensembl chr20:14,322,985...14,337,614

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

Antimycin A results in increased expression of FOS mRNA

NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression

Antimycin A results in increased expression of FOSB mRNA

NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179

G

FOS like 1, AP-1 transcription factor subunit

increases expression

Antimycin A results in increased expression of FOSL1 mRNA

NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573

G

forkhead box O1

multiple interactions
decreases expression

[Antimycin A co-treated with Resveratrol] results in decreased acetylation of FOXO1 protein; [FOXO1 protein co-treated with FOXO4 protein co-treated with FOXO3 protein] affects the reaction [Resveratrol inhibits the reaction [Antimycin A results in increased expression of BAX protein]]; FOXO1 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA]; FOXO1 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein]
Antimycin A results in decreased expression of FOXO1 protein

NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641

G

forkhead box O3

multiple interactions
decreases expression

[FOXO1 protein co-treated with FOXO4 protein co-treated with FOXO3 protein] affects the reaction [Resveratrol inhibits the reaction [Antimycin A results in increased expression of BAX protein]]; FOXO3 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA]; FOXO3 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein]
Antimycin A results in decreased expression of FOXO3 protein

NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774

G

forkhead box O4

multiple interactions
decreases expression

[FOXO1 protein co-treated with FOXO4 protein co-treated with FOXO3 protein] affects the reaction [Resveratrol inhibits the reaction [Antimycin A results in increased expression of BAX protein]]; FOXO4 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA]; FOXO4 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein]
Antimycin A results in decreased expression of FOXO4 protein

NCBI chr X:71,095,851...71,103,532
Ensembl chr X:71,095,851...71,103,535

G

folylpolyglutamate synthase

decreases expression

Antimycin A results in decreased expression of FPGS mRNA

NCBI chr 9:127,802,858...127,814,506
Ensembl chr 9:127,794,597...127,814,494

G

ferritin heavy chain 1

increases expression

Antimycin A results in increased expression of FTH1 mRNA

NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634

G

ferritin light chain

increases expression

Antimycin A results in increased expression of FTL mRNA

NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,967,896

G

fucosyltransferase 1 (H blood group)

increases expression

Antimycin A results in increased expression of FUT1 mRNA

NCBI chr19:48,748,011...48,755,358
Ensembl chr19:48,748,011...48,755,390

G

FYN proto-oncogene, Src family tyrosine kinase

decreases expression

Antimycin A results in decreased expression of FYN mRNA

NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452

G

frizzled class receptor 1

decreases expression

Antimycin A results in decreased expression of FZD1 mRNA

NCBI chr 7:91,264,433...91,271,326
Ensembl chr 7:91,264,433...91,271,326

G

frizzled class receptor 2

decreases expression

Antimycin A results in decreased expression of FZD2 mRNA

NCBI chr17:44,557,484...44,561,262
Ensembl chr17:44,557,484...44,561,262

G

glucose-6-phosphate dehydrogenase

decreases expression

Antimycin A results in decreased expression of G6PD mRNA

NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572

G

GA binding protein transcription factor subunit beta 1

increases expression

Antimycin A results in increased expression of GABPB1 mRNA

NCBI chr15:50,275,389...50,355,198
Ensembl chr15:50,275,389...50,355,408

G

growth arrest and DNA damage inducible alpha

increases expression

Antimycin A results in increased expression of GADD45A mRNA

PMID:19304788 PMID:33512557

NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334

G

growth arrest and DNA damage inducible beta

increases expression

Antimycin A results in increased expression of GADD45B mRNA

NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805

G

polypeptide N-acetylgalactosaminyltransferase 3

decreases expression

Antimycin A results in decreased expression of GALNT3 mRNA

NCBI chr 2:165,747,588...165,794,692
Ensembl chr 2:165,747,588...165,846,201

G

growth associated protein 43

decreases expression

Antimycin A results in decreased expression of GAP43 mRNA

NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490

G

GATA binding protein 2

increases expression

Antimycin A results in increased expression of GATA2 mRNA

NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201

G

GTP cyclohydrolase 1

increases expression

Antimycin A results in increased expression of GCH1 mRNA

NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826

G

glutamate-cysteine ligase modifier subunit

increases expression

Antimycin A results in increased expression of GCLM mRNA

NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456

G

growth differentiation factor 15

increases expression

Antimycin A results in increased expression of GDF15 mRNA

NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176

G

gem nuclear organelle associated protein 5

decreases expression

Antimycin A results in decreased expression of GEMIN5 mRNA

NCBI chr 5:154,887,411...154,938,211
Ensembl chr 5:154,887,411...154,938,211

G

Gfo/Idh/MocA-like oxidoreductase domain containing 1

increases expression

Antimycin A results in increased expression of GFOD1 mRNA

NCBI chr 6:13,357,830...13,487,600
Ensembl chr 6:13,357,830...13,487,662

G

GINS complex subunit 2

increases expression

Antimycin A results in increased expression of GINS2 mRNA

NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073

G

gap junction protein alpha 1

increases expression

Antimycin A results in increased expression of GJA1 mRNA

NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727

G

glycine decarboxylase

decreases expression

Antimycin A results in decreased expression of GLDC mRNA

NCBI chr 9:6,532,467...6,645,729
Ensembl chr 9:6,532,467...6,645,729

G

GLI family zinc finger 3

decreases expression

Antimycin A results in decreased expression of GLI3 mRNA

NCBI chr 7:41,960,949...42,264,268
Ensembl chr 7:41,960,949...42,264,100

G

geminin DNA replication inhibitor

increases expression

Antimycin A results in increased expression of GMNN mRNA

NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099

G

G protein subunit alpha i2

decreases expression

Antimycin A results in decreased expression of GNAI2 mRNA

NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362

G

glucosamine-6-phosphate deaminase 1

decreases expression

Antimycin A results in decreased expression of GNPDA1 mRNA

NCBI chr 5:142,000,671...142,013,027
Ensembl chr 5:141,991,749...142,013,041

G

glypican 1

decreases expression

Antimycin A results in decreased expression of GPC1 mRNA

NCBI chr 2:240,435,663...240,468,076
Ensembl chr 2:240,435,663...240,468,076

G

growth factor receptor bound protein 10

increases expression

Antimycin A results in increased expression of GRB10 mRNA

NCBI chr 7:50,590,068...50,793,453
Ensembl chr 7:50,590,063...50,793,462

G

glutamate ionotropic receptor AMPA type subunit 2

decreases expression

Antimycin A results in decreased expression of GRIA2 mRNA

NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146

G

glutamate metabotropic receptor 4

decreases expression

Antimycin A results in decreased expression of GRM4 mRNA

NCBI chr 6:34,018,643...34,155,622
Ensembl chr 6:34,018,643...34,155,622

G

glutathione S-transferase alpha 5

increases expression

Antimycin A results in increased expression of GSTA1 mRNA

NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843

G

glutathione S-transferase mu 2

decreases expression

Antimycin A results in decreased expression of GSTM2 mRNA

NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551

G

H1.2 linker histone, cluster member

increases expression

Antimycin A results in increased expression of H1-2 mRNA

NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,054,760...26,056,470

G

H2A clustered histone 11

increases expression

Antimycin A results in increased expression of H2AC11 mRNA

NCBI chr 6:27,133,043...27,133,535
Ensembl chr 6:27,133,043...27,135,292

G

H2A clustered histone 15

increases expression

Antimycin A results in increased expression of H2AC15 mRNA

NCBI chr 6:27,837,880...27,838,375
Ensembl chr 6:27,835,508...27,838,375

G

H2A clustered histone 19

increases expression

Antimycin A results in increased expression of H2AC19 mRNA

NCBI chr 1:149,851,061...149,851,594
Ensembl chr 1:149,851,061...149,851,594

G

H2A clustered histone 6

increases expression

Antimycin A results in increased expression of H2AC6 mRNA

NCBI chr 6:26,124,172...26,124,690
Ensembl chr 6:26,124,145...26,139,116

G

H2B clustered histone 14

increases expression

Antimycin A results in increased expression of H2BC14 mRNA

NCBI chr 6:27,815,022...27,815,489
Ensembl chr 6:27,815,022...27,815,489

G

H2B clustered histone 15

increases expression

Antimycin A results in increased expression of H2BC15 mRNA

NCBI chr 6:27,838,569...27,839,110
Ensembl chr 6:27,838,545...27,855,709

G

H2B clustered histone 3

increases expression

Antimycin A results in increased expression of H2BC3 mRNA

NCBI chr 6:26,043,227...26,043,713
Ensembl chr 6:26,042,771...26,043,713

G

H2B clustered histone 5

increases expression

Antimycin A results in increased expression of H2BC5 mRNA

NCBI chr 6:26,158,121...26,171,349
Ensembl chr 6:26,158,122...26,171,349

G

H3 clustered histone 10

increases expression

Antimycin A results in increased expression of H3C10 mRNA

NCBI chr 6:27,810,051...27,810,536
Ensembl chr 6:27,810,051...27,811,300

G

H3 clustered histone 2

increases expression

Antimycin A results in increased expression of H3C2 mRNA

NCBI chr 6:26,031,589...26,032,099
Ensembl chr 6:26,031,589...26,032,099

G

H3 clustered histone 4

increases expression

Antimycin A results in increased expression of H3C4 mRNA

NCBI chr 6:26,196,784...26,199,293
Ensembl chr 6:26,195,164...26,197,286

G

hemoglobin subunit alpha 2

increases expression

Antimycin A results in increased expression of HBA2 mRNA

NCBI chr16:172,876...173,710
Ensembl chr16:172,876...173,710

G

histone deacetylase 2

decreases expression

Antimycin A results in decreased expression of HDAC2 mRNA

NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308

G

HECT and RLD domain containing E3 ubiquitin protein ligase 5

increases expression

Antimycin A results in increased expression of HERC5 mRNA

NCBI chr 4:88,457,119...88,506,163
Ensembl chr 4:88,457,119...88,506,163

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

Antimycin A results in increased expression of HERPUD1 mRNA

NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864

G

hes family bHLH transcription factor 1

increases expression

Antimycin A results in increased expression of HES1 mRNA

NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732

G

hes family bHLH transcription factor 5

increases expression

Antimycin A results in increased expression of HES5 mRNA

NCBI chr 1:2,528,745...2,530,263
Ensembl chr 1:2,528,745...2,530,263

G

hypoxia inducible factor 1 subunit alpha

affects expression
multiple interactions
increases expression

Antimycin A affects the expression of HIF1A protein
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of HIF1A mRNA]

PMID:16034640 PMID:35430258

NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259

G

major histocompatibility complex, class I, A

increases expression

Antimycin A results in increased expression of HLA-A mRNA

NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572

G

major histocompatibility complex, class I, E

increases expression

Antimycin A results in increased expression of HLA-E mRNA

NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194

G

high mobility group AT-hook 2

increases expression

Antimycin A results in increased expression of HMGA2 mRNA

NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291

G

hyaluronan mediated motility receptor

increases expression

Antimycin A results in increased expression of HMMR mRNA

NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941

G

heme oxygenase 1

increases expression

Antimycin A results in increased expression of HMOX1 mRNA

NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214

G

heat shock protein 90 alpha family class A member 1

increases expression

Antimycin A results in increased expression of HSP90AA1 mRNA

NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699

G

heat shock protein 90 alpha family class B member 1

increases expression

Antimycin A results in increased expression of HSP90AB1 mRNA

NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888

G

heat shock protein family A (Hsp70) member 1A

increases expression

Antimycin A results in increased expression of HSPA1A mRNA

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946

G

heat shock protein family A (Hsp70) member 1B

increases expression

Antimycin A results in increased expression of HSPA1B mRNA

NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254

G

heat shock protein family A (Hsp70) member 2

increases expression

Antimycin A results in increased expression of HSPA2 mRNA

NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173

G

heat shock protein family A (Hsp70) member 5

increases expression

Antimycin A results in increased expression of HSPA5 protein
Antimycin A results in increased expression of HSPA5 mRNA

PMID:21337367 PMID:33512557

NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382

G

heat shock protein family A (Hsp70) member 6

increases expression

Antimycin A results in increased expression of HSPA6 mRNA

NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894

G

heat shock protein family B (small) member 1

increases expression

Antimycin A results in increased expression of HSPB1 mRNA

NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813

G

heat shock protein family B (small) member 8

increases expression

Antimycin A results in increased expression of HSPB8 mRNA

NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855

G

heat shock protein family D (Hsp60) member 1

increases expression

Antimycin A results in increased expression of HSPD1 mRNA

NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737

G

heat shock protein family E (Hsp10) member 1

increases expression

Antimycin A results in increased expression of HSPE1 mRNA

NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449

G

HtrA serine peptidase 1

increases expression

Antimycin A results in increased expression of HTRA1 mRNA

NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907

G

intercellular adhesion molecule 1

multiple interactions
decreases expression

Antimycin A inhibits the reaction [N-caproylsphingosine results in increased expression of ICAM1 mRNA]
Antimycin A results in decreased expression of ICAM1 mRNA

PMID:12952965 PMID:19304788

NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615

G

inhibitor of DNA binding 2

increases expression

Antimycin A results in increased expression of ID2 mRNA

NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

Antimycin A results in decreased expression of IDI1 mRNA

NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119

G

immediate early response 3

increases expression

Antimycin A results in increased expression of IER3 mRNA

NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548

G

interferon induced protein 44 like

increases expression

Antimycin A results in increased expression of IFI44L mRNA

NCBI chr 1:78,620,448...78,646,145
Ensembl chr 1:78,619,902...78,646,145

G

interferon induced protein with tetratricopeptide repeats 1

increases expression

Antimycin A results in increased expression of IFIT1 mRNA

NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487

G

interferon induced transmembrane protein 1

increases expression

Antimycin A results in increased expression of IFITM1 mRNA

NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272

G

interferon induced transmembrane protein 3

decreases expression

Antimycin A results in decreased expression of IFITM3 mRNA

NCBI chr11:319,676...320,860
Ensembl chr11:319,676...329,475

G

interferon related developmental regulator 1

increases expression

Antimycin A results in increased expression of IFRD1 mRNA

NCBI chr 7:112,423,174...112,477,203
Ensembl chr 7:112,422,887...112,481,017

G

interferon related developmental regulator 2

increases expression

Antimycin A results in increased expression of IFRD2 mRNA

NCBI chr 3:50,287,732...50,292,429
Ensembl chr 3:50,287,732...50,292,918

G

insulin like growth factor binding protein 2

decreases expression

Antimycin A results in decreased expression of IGFBP2 mRNA

NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436

G

IKBKB interacting protein

increases expression

Antimycin A results in increased expression of IKBIP mRNA

NCBI chr12:98,613,404...98,644,788
Ensembl chr12:98,613,405...98,645,113

G

interleukin 1 beta

multiple interactions

Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Antimycin A promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Antimycin A promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; Antimycin A promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]; BAY 11-7085 inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; IL1B protein promotes the reaction [Antimycin A results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]

PMID:22549761 PMID:24609059

NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816

G

interleukin 3 receptor subunit alpha

decreases expression

Antimycin A results in decreased expression of IL3RA mRNA

NCBI chr  X:1,336,785...1,382,689
NCBI chr  Y:1,336,785...1,382,689
Ensembl chr  Y:1,336,616...1,382,689
Ensembl chr  X:1,336,616...1,382,689

G

interleukin 6

increases expression
multiple interactions

Antimycin A results in increased expression of IL6 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of IL6 protein]; 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased expression of IL6 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of IL6 protein]; Antimycin A results in increased expression of and results in increased secretion of IL6 protein; Cyclosporine inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of IL6 protein]

PMID:21381053 PMID:21910134

NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002

G

interleukin 6 receptor

decreases expression

Antimycin A results in decreased expression of IL6R protein modified form

NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450

G

internexin neuronal intermediate filament protein alpha

decreases expression

Antimycin A results in decreased expression of INA mRNA

NCBI chr10:103,277,138...103,290,346
Ensembl chr10:103,277,138...103,290,346

G

inositol polyphosphate-1-phosphatase

increases expression

Antimycin A results in increased expression of INPP1 mRNA

NCBI chr 2:190,343,589...190,371,665
Ensembl chr 2:190,343,570...190,371,665

G

inositol polyphosphate-5-phosphatase F

decreases expression

Antimycin A results in decreased expression of INPP5F mRNA

NCBI chr10:119,726,050...119,829,147
Ensembl chr10:119,726,042...119,829,147

G

insulin induced gene 1

increases expression

Antimycin A results in increased expression of INSIG1 mRNA

NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235

G

INSM transcriptional repressor 1

decreases expression

Antimycin A results in decreased expression of INSM1 mRNA

NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949

G

importin 5

increases expression

Antimycin A results in increased expression of IPO5 mRNA

NCBI chr13:97,953,675...98,024,296
Ensembl chr13:97,953,658...98,024,296

G

interferon regulatory factor 1

increases expression

Antimycin A results in increased expression of IRF1 mRNA

NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719

G

ISL LIM homeobox 1

decreases expression

Antimycin A results in decreased expression of ISL1 mRNA

NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730

G

integrin subunit beta 7

increases expression

Antimycin A results in increased expression of ITGB7 mRNA

NCBI chr12:53,191,323...53,207,251
Ensembl chr12:53,191,323...53,207,282

G

inositol 1,4,5-trisphosphate receptor type 2

decreases expression

Antimycin A results in decreased expression of ITPR2 mRNA

NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

increases expression

Antimycin A results in increased expression of JMJD6 mRNA

NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

Antimycin A results in increased expression of JUN protein
[Antimycin A co-treated with Paraquat] results in increased expression of JUN protein

NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048

G

lysine demethylase 3A

decreases expression

Antimycin A results in decreased expression of KDM3A mRNA

NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716

G

lysine demethylase 5B

decreases expression

Antimycin A results in decreased expression of KDM5B mRNA

NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487

G

KIAA0753

decreases expression

Antimycin A results in decreased expression of KIAA0753 mRNA

NCBI chr17:6,578,147...6,640,711
Ensembl chr17:6,578,147...6,640,711

G

kinesin family member 14

increases expression

Antimycin A results in increased expression of KIF14 mRNA

NCBI chr 1:200,551,497...200,620,751
Ensembl chr 1:200,551,497...200,620,751

G

kinesin family member 15

increases expression

Antimycin A results in increased expression of KIF15 mRNA

NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376

G

kinesin family member 20A

increases expression

Antimycin A results in increased expression of KIF20A mRNA

NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723

G

kinesin family member 23

increases expression

Antimycin A results in increased expression of KIF23 mRNA

NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427

G

kinesin family member 2C

increases expression

Antimycin A results in increased expression of KIF2C mRNA

NCBI chr 1:44,739,837...44,767,767
Ensembl chr 1:44,739,818...44,767,767

G

kinesin family member 5C

decreases expression

Antimycin A results in decreased expression of KIF5C mRNA

NCBI chr 2:148,875,227...149,026,759
Ensembl chr 2:148,875,227...149,026,759

G

KLF transcription factor 5

increases expression

Antimycin A results in increased expression of KLF5 mRNA

NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541

G

KLF transcription factor 6

increases expression

Antimycin A results in increased expression of KLF6 mRNA

NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281

G

kelch like family member 24

increases expression

Antimycin A results in increased expression of KLHL24 mRNA

NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519

G

kelch like family member 9

decreases expression

Antimycin A results in decreased expression of KLHL9 mRNA

NCBI chr 9:21,329,665...21,335,404
Ensembl chr 9:21,320,024...21,335,404

G

keratin 17

increases expression

Antimycin A results in increased expression of KRT17 mRNA

NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842

G

keratin 19

decreases expression

Antimycin A results in decreased expression of KRT19 mRNA

NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308

G

kynurenine aminotransferase 3

decreases expression

Antimycin A results in decreased expression of KYAT3 mRNA

NCBI chr 1:88,921,044...88,992,960
Ensembl chr 1:88,935,773...88,992,953

G

L1 cell adhesion molecule

decreases expression

Antimycin A results in decreased expression of L1CAM mRNA

NCBI chr X:153,861,514...153,886,173
Ensembl chr X:153,861,514...153,886,173

G

lysosomal associated membrane protein 1

multiple interactions
decreases expression

[PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA
Antimycin A results in decreased expression of LAMP1 mRNA

PMID:28366621 PMID:33512557

NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672

G

leiomodin 1

decreases expression

Antimycin A results in decreased expression of LMOD1 mRNA

NCBI chr 1:201,896,456...201,946,548
Ensembl chr 1:201,896,456...201,946,548

G

lysyl oxidase like 1

decreases expression

Antimycin A results in decreased expression of LOXL1 mRNA

NCBI chr15:73,926,462...73,952,136
Ensembl chr15:73,925,989...73,952,137

G

LDL receptor related protein 4

decreases expression

Antimycin A results in decreased expression of LRP4 mRNA

NCBI chr11:46,856,717...46,918,550
Ensembl chr11:46,856,717...46,918,642

G

leucine rich repeat containing 41

decreases expression

Antimycin A results in decreased expression of LRRC41 mRNA

NCBI chr 1:46,277,462...46,303,616
Ensembl chr 1:46,261,196...46,303,616

G

LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

decreases expression

Antimycin A results in decreased expression of LSM6 mRNA

NCBI chr 4:146,175,718...146,191,535
Ensembl chr 4:146,175,703...146,200,000

G

lumican

increases expression

Antimycin A results in increased expression of LUM mRNA

NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494

G

microtubule actin crosslinking factor 1

decreases expression

Antimycin A results in decreased expression of MACF1 mRNA

NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177

G

MAF bZIP transcription factor F

increases expression

Antimycin A results in increased expression of MAFF mRNA

NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507

G

metastasis associated lung adenocarcinoma transcript 1

decreases expression

Antimycin A results in decreased expression of MALAT1 mRNA

NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,606...65,508,073

G

microtubule associated protein 1B

decreases expression

Antimycin A results in decreased expression of MAP1B mRNA

NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565

G

microtubule associated protein 1 light chain 3 beta

increases expression

Antimycin A results in increased expression of MAP1LC3B mRNA

NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779

G

microtubule associated protein 2

decreases expression

Antimycin A results in decreased expression of MAP2 mRNA

NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147

G

mitogen-activated protein kinase kinase 4

decreases expression

Antimycin A results in decreased expression of MAP2K4 mRNA

NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830

G

microtubule associated protein 6

decreases expression

Antimycin A results in decreased expression of MAP6 mRNA

NCBI chr11:75,586,918...75,669,038
Ensembl chr11:75,586,918...75,669,038

G

mitogen-activated protein kinase 14

multiple interactions

Antimycin A inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]

NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511

G

mitogen-activated protein kinase 3

decreases expression

Antimycin A results in decreased expression of MAPK3 mRNA

NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506

G

microtubule associated protein RP/EB family member 3

decreases expression

Antimycin A results in decreased expression of MAPRE3 mRNA

NCBI chr 2:26,970,637...27,027,219
Ensembl chr 2:26,970,637...27,027,219

G

microtubule associated protein tau

decreases expression

Antimycin A results in decreased expression of MAPT mRNA

NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334

G

muscleblind like splicing regulator 2

increases expression

Antimycin A results in increased expression of MBNL2 mRNA

NCBI chr13:97,141,834...97,394,120
Ensembl chr13:97,221,434...97,394,120

G

MCL1 apoptosis regulator, BCL2 family member

increases expression

Antimycin A results in increased expression of MCL1 mRNA

NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738

G

minichromosome maintenance complex component 7

increases expression

Antimycin A results in increased expression of MCM7 mRNA

NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940

G

midkine

increases expression

Antimycin A results in increased expression of MDK mRNA

NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837

G

MDM2 proto-oncogene

increases expression

Antimycin A results in increased expression of MDM2 mRNA

NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544

G

malic enzyme 1

increases expression

Antimycin A results in increased expression of ME1 mRNA

NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051

G

mediator complex subunit 21

increases expression

Antimycin A results in increased expression of MED21 mRNA

NCBI chr12:27,022,558...27,038,951
Ensembl chr12:27,022,546...27,066,343

G

MEFV innate immunity regulator, pyrin

increases expression

Antimycin A results in increased expression of MEFV mRNA

NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633

G

meteorin, glial cell differentiation regulator

decreases expression

Antimycin A results in decreased expression of METRN mRNA

NCBI chr16:715,118...719,655
Ensembl chr16:715,118...719,655

G

marker of proliferation Ki-67

increases expression

Antimycin A results in increased expression of MKI67 mRNA

NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423

G

MLLT11 transcription factor 7 cofactor

decreases expression

Antimycin A results in decreased expression of MLLT11 mRNA

NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544

G

matrix metallopeptidase 13

increases expression

Antimycin A results in increased expression of MMP13 mRNA

NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732

G

matrix metallopeptidase 2

multiple interactions
increases activity

[Antimycin A results in increased abundance of Reactive Oxygen Species] which results in increased activity of MMP2 protein
Antimycin A results in increased activity of MMP2 protein

NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691

G

MNAT1 component of CDK activating kinase

decreases expression

Antimycin A results in decreased expression of MNAT1 mRNA

NCBI chr14:60,734,761...60,969,965
Ensembl chr14:60,734,742...60,969,965

G

MORN repeat containing 2

decreases expression

Antimycin A results in decreased expression of MORN2 mRNA

NCBI chr 2:38,875,976...38,882,709
Ensembl chr 2:38,875,976...38,929,072

G

MRE11 homolog, double strand break repair nuclease

decreases expression

Antimycin A results in decreased expression of MRE11 mRNA

NCBI chr11:94,415,570...94,512,412
Ensembl chr11:94,415,570...94,493,885

G

musashi RNA binding protein 2

decreases expression

Antimycin A results in decreased expression of MSI2 mRNA

NCBI chr17:57,255,851...57,701,581
Ensembl chr17:57,255,851...57,684,689

G

MSL complex subunit 1

increases expression

Antimycin A results in increased expression of MSL1 mRNA

NCBI chr17:40,121,971...40,136,917
Ensembl chr17:40,121,971...40,136,917

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

decreases expression

Antimycin A results in decreased expression of ND6 mRNA

NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673

G

metastasis associated 1

decreases expression

Antimycin A results in decreased expression of MTA1 mRNA

NCBI chr14:105,419,827...105,470,729
Ensembl chr14:105,419,820...105,470,729

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

increases expression

Antimycin A results in increased expression of MTHFD2 mRNA

NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565

G

mechanistic target of rapamycin kinase

increases expression
multiple interactions

Antimycin A results in increased expression of MTOR mRNA
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of MTOR mRNA]

NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556

G

MYB proto-oncogene like 2

increases expression

Antimycin A results in increased expression of MYBL2 mRNA

NCBI chr20:43,667,114...43,716,482
Ensembl chr20:43,667,019...43,716,495

G

MYC proto-oncogene, bHLH transcription factor

increases expression

Antimycin A results in increased expression of MYC mRNA

NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951

G

MYC binding protein 2

decreases expression

Antimycin A results in decreased expression of MYCBP2 mRNA

NCBI chr13:77,044,657...77,327,094
Ensembl chr13:77,042,474...77,327,094

G

myogenic differentiation 1

decreases expression

Antimycin A results in decreased expression of MYOD1 mRNA

NCBI chr11:17,719,571...17,722,136
Ensembl chr11:17,719,571...17,722,136

G

myogenin

decreases expression

Antimycin A results in decreased expression of MYOG mRNA

NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012

G

neuron navigator 1

decreases expression

Antimycin A results in decreased expression of NAV1 mRNA

NCBI chr 1:201,539,127...201,826,969
Ensembl chr 1:201,539,127...201,826,969

G

neural cell adhesion molecule 1

decreases expression

Antimycin A results in decreased expression of NCAM1 mRNA

NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436

G

neurocan

decreases expression

Antimycin A results in decreased expression of NCAN mRNA

NCBI chr19:19,211,958...19,252,233
Ensembl chr19:19,211,958...19,252,233

G

non-SMC condensin I complex subunit H

increases expression

Antimycin A results in increased expression of NCAPH mRNA

NCBI chr 2:96,335,766...96,377,091
Ensembl chr 2:96,335,766...96,377,091

G

N-myc downstream regulated 1

increases expression

Antimycin A results in increased expression of NDRG1 mRNA

NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022

G

neurofilament light chain

decreases expression

Antimycin A results in decreased expression of NEFL mRNA

NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721

G

NIMA related kinase 2

increases expression

Antimycin A results in increased expression of NEK2 mRNA

NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630

G

nuclear factor of activated T cells 3

decreases expression

Antimycin A results in decreased expression of NFATC3 mRNA

NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259

G

NFE2 like bZIP transcription factor 1

increases expression

Antimycin A results in increased expression of NFE2L1 mRNA

NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545

G

NFE2 like bZIP transcription factor 2

increases expression
multiple interactions

Antimycin A results in increased expression of NFE2L2 mRNA
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of NFE2L2 mRNA]

NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756

G

NFKB inhibitor alpha

multiple interactions

Antimycin A inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

nescient helix-loop-helix 1

decreases expression

Antimycin A results in decreased expression of NHLH1 mRNA

NCBI chr 1:160,367,071...160,372,846
Ensembl chr 1:160,367,071...160,372,846

G

nitrilase 1

decreases expression

Antimycin A results in decreased expression of NIT1 mRNA

NCBI chr 1:161,118,105...161,125,445
Ensembl chr 1:161,118,086...161,125,445

G

nicotinamide nucleotide transhydrogenase

decreases expression

Antimycin A results in decreased expression of NNT mRNA

NCBI chr 5:43,602,675...43,707,396
Ensembl chr 5:43,602,692...43,707,405

G

nucleolar protein 3

decreases expression

Antimycin A results in decreased expression of NOL3 mRNA

NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737

G

NOP58 ribonucleoprotein

increases expression

Antimycin A results in increased expression of NOP58 mRNA

NCBI chr 2:202,265,763...202,303,661
Ensembl chr 2:202,265,736...202,303,661

G

notch receptor 3

decreases expression

Antimycin A results in decreased expression of NOTCH3 mRNA

NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995

G

NPC intracellular cholesterol transporter 1

decreases expression

Antimycin A results in decreased expression of NPC1 mRNA

NCBI chr18:23,506,184...23,586,506
Ensembl chr18:23,506,184...23,586,506

G

neuronal pentraxin 1

increases expression

Antimycin A results in increased expression of NPTX1 mRNA

NCBI chr17:80,466,834...80,476,607
Ensembl chr17:80,466,834...80,477,843

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions

Antimycin A results in increased expression of NQO1 mRNA
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of NQO1 mRNA]

PMID:33512557 PMID:35430258

NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668

G

nuclear receptor subfamily 2 group F member 1

decreases expression

Antimycin A results in decreased expression of NR2F1 mRNA

NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611

G

nuclear receptor subfamily 3 group C member 1

increases expression

Antimycin A results in increased expression of NR3C1 mRNA

NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512

G

nuclear receptor subfamily 4 group A member 2

increases expression

Antimycin A results in increased expression of NR4A2 mRNA

NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348

G

nuclear receptor subfamily 5 group A member 1

decreases expression

Antimycin A results in decreased expression of NR5A1 mRNA

NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420

G

NRAS proto-oncogene, GTPase

decreases expression

Antimycin A results in decreased expression of NRAS mRNA

NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771

G

neuronal cell adhesion molecule

decreases expression

Antimycin A results in decreased expression of NRCAM mRNA

NCBI chr 7:108,147,649...108,456,720
Ensembl chr 7:108,147,623...108,456,717

G

neuregulin 1

decreases expression

Antimycin A results in decreased expression of NRG1 mRNA

NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666

G

neuropilin 1

decreases expression

Antimycin A results in decreased expression of NRP1 mRNA

NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262

G

neurexin 1

decreases expression

Antimycin A results in decreased expression of NRXN1 mRNA

NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575

G

5'-nucleotidase ecto

increases expression

Antimycin A results in increased expression of NT5E mRNA

NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791

G

nucleoporin 50

increases expression

Antimycin A results in increased expression of NUP50 mRNA

NCBI chr22:45,163,925...45,188,017
Ensembl chr22:45,163,925...45,188,017

G

nuclear protein 1, transcriptional regulator

increases expression

Antimycin A results in increased expression of NUPR1 mRNA

NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008

G

NUS1 pseudogene 3

increases expression

Antimycin A results in increased expression of NUS1P3 mRNA

NCBI chr13:24,327,708...24,332,108
Ensembl chr13:24,328,211...24,329,072

G

Opa interacting protein 5

increases expression

Antimycin A results in increased expression of OIP5 mRNA

NCBI chr15:41,309,273...41,332,591
Ensembl chr15:41,309,273...41,332,591

G

one cut homeobox 1

decreases expression

Antimycin A results in decreased expression of ONECUT1 mRNA

NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078

G

oligophrenin 1

decreases expression

Antimycin A results in decreased expression of OPHN1 mRNA

NCBI chr X:68,042,344...68,433,841
Ensembl chr X:67,949,349...68,433,913

G

purinergic receptor P2X 3

decreases expression

Antimycin A results in decreased expression of P2RX3 mRNA

NCBI chr11:57,335,950...57,372,396
Ensembl chr11:57,338,352...57,372,396

G

platelet activating factor acetylhydrolase 1b catalytic subunit 3

decreases expression

Antimycin A results in decreased expression of PAFAH1B3 mRNA

NCBI chr19:42,297,033...42,302,800
Ensembl chr19:42,297,033...42,303,546

G

poly(ADP-ribose) polymerase 1

multiple interactions
increases cleavage

[Antimycin A co-treated with Paraquat] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of PARP1 protein]

PMID:16237197 PMID:32662599

NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154

G

poly(ADP-ribose) polymerase 2

increases expression

Antimycin A results in increased expression of PARP2 mRNA

NCBI chr14:20,343,635...20,357,904
Ensembl chr14:20,343,615...20,357,904

G

PDZ binding kinase

increases expression

Antimycin A results in increased expression of PBK mRNA

NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082

G

protocadherin 8

increases expression

Antimycin A results in increased expression of PCDH8 mRNA

NCBI chr13:52,842,889...52,848,640
Ensembl chr13:52,842,889...52,848,641

G

protocadherin alpha 9

decreases expression

Antimycin A results in decreased expression of PCDHA9 mRNA

NCBI chr 5:140,847,772...141,012,347
Ensembl chr 5:140,847,772...141,012,347

G

phosphoenolpyruvate carboxykinase 1

increases expression

Antimycin A results in increased expression of PCK1 mRNA

NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121

G

programmed cell death 6 interacting protein

decreases expression

Antimycin A results in decreased expression of PDCD6IP mRNA

NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707

G

protein disulfide isomerase family A member 5

increases expression

Antimycin A results in increased expression of PDIA5 mRNA

NCBI chr 3:123,067,025...123,162,104
Ensembl chr 3:123,067,025...123,225,227

G

protein disulfide isomerase family A member 6

increases expression

Antimycin A results in increased expression of PDIA6 mRNA

NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977

G

pyruvate dehydrogenase kinase 4

increases expression

Antimycin A results in increased expression of PDK4 mRNA

NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516

G

phosphatidylethanolamine binding protein 1

decreases expression

Antimycin A results in decreased expression of PEBP1 mRNA

NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584

G

paternally expressed 10

decreases expression

Antimycin A results in decreased expression of PEG10 mRNA

NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695

G

peroxisomal biogenesis factor 3

decreases expression

Antimycin A results in decreased expression of PEX3 mRNA

NCBI chr 6:143,450,805...143,490,616
Ensembl chr 6:143,450,805...143,490,616

G

phosphofructokinase, platelet

increases expression

Antimycin A results in increased expression of PFKP mRNA

NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718

G

pepsinogen A5

increases expression

Antimycin A results in increased expression of PGA5 mRNA

NCBI chr11:61,241,175...61,251,444
Ensembl chr11:61,241,175...61,251,444

G

phosphoglycerate kinase 1

decreases expression

Antimycin A results in decreased expression of PGK1 mRNA

NCBI chr X:78,104,248...78,129,295
Ensembl chr X:77,910,739...78,129,295

G

phosphoglucomutase 3

increases expression

Antimycin A results in increased expression of PGM3 mRNA

NCBI chr 6:83,148,705...83,193,900
Ensembl chr 6:83,147,324...83,193,936

G

phosphoglycerate dehydrogenase

increases expression

Antimycin A results in increased expression of PHGDH mRNA

NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218

G

phosphorylase kinase regulatory subunit beta

decreases expression

Antimycin A results in decreased expression of PHKB mRNA

NCBI chr16:47,461,299...47,701,523
Ensembl chr16:47,461,123...47,701,523

G

pleckstrin homology like domain family A member 1

decreases expression

Antimycin A results in decreased expression of PHLDA1 mRNA

NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776

G

PTEN induced kinase 1

multiple interactions
decreases expression

[PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein]; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA]; PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]]
Antimycin A results in decreased expression of PINK1 mRNA

PMID:28366621 PMID:33512557

NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511

G

phosphatidylinositol-5-phosphate 4-kinase type 2 beta

decreases expression

Antimycin A results in decreased expression of PIP4K2B mRNA

NCBI chr17:38,765,691...38,799,556
Ensembl chr17:38,765,691...38,800,126

G

phosphatidylinositol transfer protein alpha

decreases expression

Antimycin A results in decreased expression of PITPNA mRNA

NCBI chr17:1,517,718...1,562,792
Ensembl chr17:1,517,718...1,562,792

G

phospholipid scramblase 3

decreases expression

Antimycin A results in decreased expression of PLSCR3 mRNA

NCBI chr17:7,389,727...7,394,525
Ensembl chr17:7,389,727...7,394,842

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

Antimycin A results in increased expression of PMAIP1 mRNA

NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305

G

DNA polymerase epsilon 3, accessory subunit

increases expression

Antimycin A results in increased expression of POLE3 mRNA

NCBI chr 9:113,407,235...113,410,749
Ensembl chr 9:113,407,235...113,410,675

G

RNA polymerase I and III subunit C

increases expression

Antimycin A results in increased expression of POLR1C mRNA

NCBI chr 6:43,517,089...43,562,407
Ensembl chr 6:43,509,702...43,562,419

G

RNA polymerase II, I and III subunit H

increases expression

Antimycin A results in increased expression of POLR2H mRNA

NCBI chr 3:184,361,710...184,368,591
Ensembl chr 3:184,361,710...184,368,596

G

POTE ankyrin domain family member M

decreases expression

Antimycin A results in decreased expression of POTEM mRNA

NCBI chr14:18,967,434...19,003,752
Ensembl chr14:18,967,434...19,003,752

G

POU class 4 homeobox 1

decreases expression

Antimycin A results in decreased expression of POU4F1 mRNA

NCBI chr13:78,598,362...78,603,552
Ensembl chr13:78,598,362...78,603,552

G

POU class 4 homeobox 2

decreases expression

Antimycin A results in decreased expression of POU4F2 mRNA

NCBI chr 4:146,638,893...146,642,474
Ensembl chr 4:146,638,893...146,642,474

G

peroxisome proliferator activated receptor delta

decreases expression

Antimycin A results in decreased expression of PPARD mRNA

NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191

G

PPARG coactivator 1 alpha

decreases expression

Antimycin A results in decreased expression of PPARGC1A protein

NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089

G

peptidylprolyl isomerase E

increases expression

Antimycin A results in increased expression of PPIE mRNA

NCBI chr 1:39,738,882...39,763,914
Ensembl chr 1:39,692,182...39,763,914

G

periplakin

decreases expression

Antimycin A results in decreased expression of PPL mRNA

NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741

G

protein phosphatase, Mg2+/Mn2+ dependent 1D

increases expression

Antimycin A results in increased expression of PPM1D mRNA

NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280

G

protein phosphatase 1 catalytic subunit gamma

increases expression

Antimycin A results in increased expression of PPP1CC mRNA

NCBI chr12:110,708,376...110,742,891
Ensembl chr12:110,719,680...110,742,939

G

protein phosphatase 1 regulatory subunit 15A

increases expression

Antimycin A results in increased expression of PPP1R15A mRNA

PMID:19304788 PMID:33512557

NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059

G

protein phosphatase 1 regulatory subunit 17

decreases expression

Antimycin A results in decreased expression of PPP1R17 mRNA

NCBI chr 7:31,687,215...31,708,455
Ensembl chr 7:31,687,215...31,708,455

G

PRA1 domain family member 2

decreases expression

Antimycin A results in decreased expression of PRAF2 mRNA

NCBI chr X:49,071,161...49,074,002
Ensembl chr X:49,071,161...49,074,002

G

peroxiredoxin 3

decreases expression

Antimycin A results in decreased expression of PRDX3 mRNA

NCBI chr10:119,167,720...119,178,812
Ensembl chr10:119,167,720...119,178,812

G

protein kinase cAMP-activated catalytic subunit alpha

decreases expression

Antimycin A results in decreased expression of PRKACA mRNA

NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084

G

protein kinase AMP-activated non-catalytic subunit gamma 1

decreases expression

Antimycin A results in decreased expression of PRKAG1 mRNA

NCBI chr12:49,002,274...49,018,776
Ensembl chr12:49,002,274...49,018,807

G

protein kinase cAMP-dependent type I regulatory subunit alpha

decreases expression

Antimycin A results in decreased expression of PRKAR1A mRNA

NCBI chr17:68,413,623...68,551,316
Ensembl chr17:68,511,780...68,551,319

G

protein kinase C beta

decreases expression

Antimycin A results in decreased expression of PRKCB mRNA

NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611

G

parkin RBR E3 ubiquitin protein ligase

multiple interactions
decreases expression

[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein; [Oligomycins co-treated with Antimycin A] affects the localization of PRKN protein; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein]
Antimycin A results in decreased expression of PRKN mRNA

PMID:28366621 PMID:28673964 PMID:33512557

NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775

G

proline rich 11

increases expression

Antimycin A results in increased expression of PRR11 mRNA

NCBI chr17:59,155,746...59,206,709
Ensembl chr17:59,155,732...59,206,709

G

phosphoserine aminotransferase 1

increases expression

Antimycin A results in increased expression of PSAT1 mRNA

NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093

G

phosphatase and tensin homolog

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of PTEN mRNA]

NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930

G

prostaglandin-endoperoxide synthase 2

increases expression
multiple interactions

Antimycin A results in increased expression of PTGS2 mRNA
Antimycin A results in increased expression of PTGS2 protein
Antimycin A promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]; IL1B protein promotes the reaction [Antimycin A results in increased expression of PTGS2 protein]

PMID:19304788 PMID:24609059

NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922

G

protein tyrosine phosphatase receptor type F

decreases expression

Antimycin A results in decreased expression of PTPRF mRNA

NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666

G

PTTG1 regulator of sister chromatid separation, securin

increases expression

Antimycin A results in increased expression of PTTG1 mRNA

NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739

G

RAB31, member RAS oncogene family

decreases expression

Antimycin A results in decreased expression of RAB31 mRNA

NCBI chr18:9,708,301...9,862,551
Ensembl chr18:9,708,275...9,862,551

G

RAD54 like

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of RAD54L mRNA]

NCBI chr 1:46,247,688...46,278,473
Ensembl chr 1:46,246,461...46,278,480

G

ral guanine nucleotide dissociation stimulator

decreases expression

Antimycin A results in decreased expression of RALGDS mRNA

NCBI chr 9:133,097,722...133,149,210
Ensembl chr 9:133,097,720...133,149,334

G

RB transcriptional corepressor like 1

decreases expression

Antimycin A results in decreased expression of RBL1 mRNA

NCBI chr20:36,996,349...37,095,997
Ensembl chr20:36,996,349...37,095,997

G

RNA binding motif protein 6

increases expression

Antimycin A results in increased expression of RBM6 mRNA

NCBI chr 3:49,940,150...50,077,249
Ensembl chr 3:49,940,007...50,100,045

G

ring-box 1

decreases expression

Antimycin A results in decreased expression of RBX1 mRNA

NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309

G

REL proto-oncogene, NF-kB subunit

increases expression

Antimycin A results in increased expression of REL mRNA

NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
affects localization

Antimycin A inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
Antimycin A affects the localization of RELA protein

PMID:24316229 PMID:24609059

NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090

G

reelin

decreases expression

Antimycin A results in decreased expression of RELN mRNA

NCBI chr 7:103,471,789...103,989,658
Ensembl chr 7:103,471,381...103,989,658

G

regulator of G protein signaling 2

increases expression

Antimycin A results in increased expression of RGS2 mRNA

NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275

G

Rho family GTPase 1

increases expression

Antimycin A results in increased expression of RND1 mRNA

NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870

G

ring finger protein 167

decreases expression

Antimycin A results in decreased expression of RNF167 mRNA

NCBI chr17:4,940,092...4,945,222
Ensembl chr17:4,940,008...4,945,222

G

RNA polymerase II associated protein 3

decreases expression

Antimycin A results in decreased expression of RPAP3 mRNA

NCBI chr12:47,661,249...47,706,030
Ensembl chr12:47,661,249...47,706,030

G

ribosomal protein L11

increases expression

Antimycin A results in increased expression of RPL11 mRNA

NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835

G

ribosomal protein L13a pseudogene 5

increases expression

Antimycin A results in increased expression of RPL13AP5 mRNA

NCBI chr10:96,750,266...96,750,923
Ensembl chr10:96,750,288...96,750,899

G

ribosomal protein L17

increases expression

Antimycin A results in increased expression of RPL17 mRNA

NCBI chr18:49,488,481...49,492,465
Ensembl chr18:49,488,453...49,492,508

G

ribosomal protein L35

increases expression

Antimycin A results in increased expression of RPL35 mRNA

NCBI chr 9:124,857,883...124,861,957
Ensembl chr 9:124,857,880...124,861,981

G

ribosomal protein L36

increases expression

Antimycin A results in increased expression of RPL36 mRNA

NCBI chr19:5,690,295...5,691,875
Ensembl chr19:5,674,947...5,691,875

G

ribosomal protein L7a

increases expression

Antimycin A results in increased expression of RPL7A mRNA

NCBI chr 9:133,348,218...133,351,426
Ensembl chr 9:133,348,218...133,351,426

G

ribosomal protein S10

decreases expression

Antimycin A results in decreased expression of RPS10 mRNA

NCBI chr 6:34,417,454...34,426,069
Ensembl chr 6:34,417,454...34,426,069

G

ribosomal protein S18

increases expression

Antimycin A results in increased expression of RPS18 mRNA

NCBI chr 6:33,272,075...33,276,511
Ensembl chr 6:33,272,075...33,276,511

G

ribosomal protein S2

increases expression

Antimycin A results in increased expression of RPS2 mRNA

NCBI chr16:1,962,058...1,964,826
Ensembl chr16:1,962,058...1,964,841

G

ribosomal protein S25

increases expression

Antimycin A results in increased expression of RPS25 mRNA

NCBI chr11:119,015,717...119,018,343
Ensembl chr11:119,015,712...119,018,691

G

ribosomal protein S3

increases expression

Antimycin A results in increased expression of RPS3 mRNA

NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280

G

ribosomal protein S5

increases expression

Antimycin A results in increased expression of RPS5 mRNA

NCBI chr19:58,387,269...58,394,804
Ensembl chr19:58,386,400...58,394,806

G

ribosomal protein S7

increases expression

Antimycin A results in increased expression of RPS7 mRNA

NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920

G

ribosomal protein SA

increases expression

Antimycin A results in increased expression of RPSA mRNA

NCBI chr 3:39,406,720...39,412,542
Ensembl chr 3:39,406,716...39,426,255

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

Antimycin A results in increased expression of RRAD mRNA

NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535

G

ribonucleotide reductase regulatory subunit M2

decreases expression
increases expression

Antimycin A results in decreased expression of RRM2 mRNA
Antimycin A results in increased expression of RRM2 mRNA

PMID:19304788 PMID:33512557

NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725

G

ribonucleotide reductase regulatory TP53 inducible subunit M2B

increases expression

Antimycin A results in increased expression of RRM2B mRNA

NCBI chr 8:102,204,501...102,238,961
Ensembl chr 8:102,204,502...102,238,961

G

ribosomal RNA processing 1B

increases expression

Antimycin A results in increased expression of RRP1B mRNA

NCBI chr21:43,659,560...43,696,079
Ensembl chr21:43,659,560...43,696,079

G

ribosomal RNA processing 8

increases expression

Antimycin A results in increased expression of RRP8 mRNA

NCBI chr11:6,595,072...6,603,616
Ensembl chr11:6,595,072...6,603,616

G

ribosome biogenesis regulator 1 homolog

increases expression

Antimycin A results in increased expression of RRS1 mRNA

NCBI chr 8:66,429,014...66,430,733
Ensembl chr 8:66,429,014...66,430,733

G

reticulon 4 interacting protein 1

decreases expression

Antimycin A results in decreased expression of RTN4IP1 mRNA

NCBI chr 6:106,570,771...106,630,491
Ensembl chr 6:106,570,771...106,629,498

G

S100 calcium binding protein A13

increases expression

Antimycin A results in increased expression of S100A13 mRNA

NCBI chr 1:153,618,799...153,634,361
Ensembl chr 1:153,618,779...153,634,412

G

S100 calcium binding protein A4

increases expression

Antimycin A results in increased expression of S100A4 mRNA

NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136

G

SAC1 like phosphatidylinositide phosphatase

decreases expression

Antimycin A results in decreased expression of SACM1L mRNA

NCBI chr 3:45,689,396...45,745,409
Ensembl chr 3:45,689,056...45,745,412

G

spermidine/spermine N1-acetyltransferase 1

increases expression

Antimycin A results in increased expression of SAT1 mRNA

NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210

G

SATB homeobox 1

decreases expression

Antimycin A results in decreased expression of SATB1 mRNA

NCBI chr 3:18,345,377...18,445,592
Ensembl chr 3:18,345,377...18,445,621

G

short coiled-coil protein

decreases expression

Antimycin A results in decreased expression of SCOC mRNA

NCBI chr 4:140,257,308...140,385,728
Ensembl chr 4:140,257,286...140,385,728

G

SEM1 26S proteasome subunit

increases expression

Antimycin A results in increased expression of SEM1 mRNA

NCBI chr 7:96,481,626...96,709,846
Ensembl chr 7:96,481,626...96,709,880

G

semaphorin 5A

increases expression

Antimycin A results in increased expression of SEMA5A mRNA

NCBI chr 5:9,035,033...9,546,075
Ensembl chr 5:9,035,033...9,546,075

G

semaphorin 6D

decreases expression

Antimycin A results in decreased expression of SEMA6D mRNA

NCBI chr15:47,184,089...47,774,228
Ensembl chr15:47,184,101...47,774,228

G

SERTA domain containing 1

increases expression

Antimycin A results in increased expression of SERTAD1 mRNA

NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992

G

sestrin 2

increases expression

Antimycin A results in increased expression of SESN2 mRNA

NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491

G

SH2 domain containing adaptor protein B

increases expression

Antimycin A results in increased expression of SHB mRNA

NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227

G

SHC binding and spindle associated 1

increases expression

Antimycin A results in increased expression of SHCBP1 mRNA

NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379

G

sirtuin 3

increases expression
multiple interactions

Antimycin A results in increased expression of SIRT3 mRNA
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA]

NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931

G

SIX homeobox 1

decreases expression

Antimycin A results in decreased expression of SIX1 mRNA

NCBI chr14:60,643,421...60,649,477
Ensembl chr14:60,643,421...60,658,259

G

solute carrier family 11 member 2

decreases expression

Antimycin A results in decreased expression of SLC11A2 mRNA

NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566

G

solute carrier family 17 member 6

decreases expression

Antimycin A results in decreased expression of SLC17A6 mRNA

NCBI chr11:22,338,381...22,379,503
Ensembl chr11:22,338,381...22,379,503

G

solute carrier family 18 member A2

increases expression

Antimycin A results in increased expression of SLC18A2 mRNA

NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430

G

solute carrier family 1 member 2

decreases expression

Antimycin A results in decreased expression of SLC1A2 mRNA

NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063

G

solute carrier family 25 member 4

decreases expression

Antimycin A results in decreased expression of SLC25A4 mRNA

NCBI chr 4:185,143,266...185,150,382
Ensembl chr 4:185,143,266...185,150,382

G

solute carrier family 2 member 6

decreases expression

Antimycin A results in decreased expression of SLC2A6 mRNA

NCBI chr 9:133,471,094...133,479,099
Ensembl chr 9:133,471,094...133,479,127

G

solute carrier family 30 member 1

increases expression

Antimycin A results in increased expression of SLC30A1 mRNA

NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161

G

solute carrier family 35 member A5

decreases expression

Antimycin A results in decreased expression of SLC35A5 mRNA

NCBI chr 3:112,561,320...112,585,579
Ensembl chr 3:112,561,709...112,585,579

G

solute carrier family 3 member 2

increases expression

Antimycin A results in increased expression of SLC3A2 mRNA

NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880

G

solute carrier family 6 member 2

increases expression

Antimycin A results in increased expression of SLC6A2 mRNA

NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645

G

solute carrier family 7 member 5

increases expression

Antimycin A results in increased expression of SLC7A5 mRNA

NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507

G

structural maintenance of chromosomes 4

increases expression

Antimycin A results in increased expression of SMC4 mRNA

NCBI chr 3:160,399,650...160,434,953
Ensembl chr 3:160,399,274...160,434,954

G

snail family transcriptional repressor 2

increases expression

Antimycin A results in increased expression of SNAI2 mRNA

PMID:19304788 PMID:33512557

NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740

G

synuclein alpha

increases expression

Antimycin A results in increased expression of SNCA mRNA

NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315

G

small nucleolar RNA host gene 8

increases expression

Antimycin A results in increased expression of SNHG8 mRNA

NCBI chr 4:118,278,762...118,279,823
Ensembl chr 4:118,278,462...118,285,316

G

small nuclear ribonucleoprotein D3 polypeptide

increases expression

Antimycin A results in increased expression of SNRPD3 mRNA

NCBI chr22:24,555,650...24,574,971
Ensembl chr22:24,555,958...24,582,052

G

sorting nexin 13

decreases expression

Antimycin A results in decreased expression of SNX13 mRNA

NCBI chr 7:17,790,761...17,940,494
Ensembl chr 7:17,790,761...17,940,501

G

sorting nexin 7

decreases expression

Antimycin A results in decreased expression of SNX7 mRNA

NCBI chr 1:98,661,319...98,760,500
Ensembl chr 1:98,661,701...98,760,500

G

suppressor of cytokine signaling 2

decreases expression

Antimycin A results in decreased expression of SOCS2 mRNA

NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487

G

suppressor of cytokine signaling 3

increases expression

Antimycin A results in increased expression of SOCS3 mRNA

NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077

G

superoxide dismutase 2

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SOD2 mRNA]; Antimycin A inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]
Antimycin A results in increased expression of SOD2 mRNA; Antimycin A results in increased expression of SOD2 protein
Antimycin A inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]
[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA; [Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein; FOXO1 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA]; FOXO1 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein]; FOXO3 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA]; FOXO3 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein]; FOXO4 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 mRNA]; FOXO4 mutant form affects the reaction [[Antimycin A co-treated with Resveratrol] affects the expression of SOD2 protein]

PMID:11264281 PMID:22718889 PMID:24040102 PMID:35430258

NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529

G

sperm associated antigen 5

increases expression

Antimycin A results in increased expression of SPAG5 mRNA

NCBI chr17:28,577,574...28,599,025
Ensembl chr17:28,577,565...28,599,025

G

SPC25 component of NDC80 kinetochore complex

increases expression

Antimycin A results in increased expression of SPC25 mRNA

NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371

G

SAM pointed domain containing ETS transcription factor

decreases expression

Antimycin A results in decreased expression of SPDEF mRNA

NCBI chr 6:34,537,802...34,556,329
Ensembl chr 6:34,537,802...34,556,333

G

sequestosome 1

multiple interactions
increases expression

[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] results in increased expression of SQSTM1 mRNA]
Antimycin A results in increased expression of SQSTM1 mRNA

PMID:19304788 PMID:28366621

NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078

G

steroid 5 alpha-reductase 1

decreases expression

Antimycin A results in decreased expression of SRD5A1 mRNA

NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539

G

SLIT-ROBO Rho GTPase activating protein 3

decreases expression

Antimycin A results in decreased expression of SRGAP3 mRNA

NCBI chr 3:8,980,591...9,363,027
Ensembl chr 3:8,980,591...9,363,053

G

serine and arginine rich splicing factor 10

increases expression

Antimycin A results in increased expression of SRSF10 mRNA

NCBI chr 1:23,964,347...23,980,327
Ensembl chr 1:23,964,347...23,980,927

G

signal sequence receptor subunit 1

decreases expression

Antimycin A results in decreased expression of SSR1 mRNA

NCBI chr 6:7,281,143...7,313,199
Ensembl chr 6:7,268,306...7,347,446

G

steroidogenic acute regulatory protein

decreases expression

Antimycin A results in decreased expression of STAR protein

NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992

G

signal transducer and activator of transcription 4

decreases expression

Antimycin A results in decreased expression of STAT4 mRNA

NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435

G

STEAP family member 1

decreases expression

Antimycin A results in decreased expression of STEAP1 mRNA

NCBI chr 7:90,154,469...90,164,827
Ensembl chr 7:90,154,456...90,164,829

G

serine/threonine kinase 25

decreases expression

Antimycin A results in decreased expression of STK25 mRNA

NCBI chr 2:241,492,670...241,509,572
Ensembl chr 2:241,492,670...241,509,730

G

SWT1 RNA endoribonuclease homolog

decreases expression

Antimycin A results in decreased expression of SWT1 mRNA

NCBI chr 1:185,157,060...185,291,781
Ensembl chr 1:185,157,080...185,291,781

G

synaptophysin

decreases expression

Antimycin A results in decreased expression of SYP mRNA

NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218

G

synaptotagmin like 1

increases expression

Antimycin A results in increased expression of SYTL1 mRNA

NCBI chr 1:27,342,022...27,353,932
Ensembl chr 1:27,342,020...27,353,937

G

transforming acidic coiled-coil containing protein 3

increases expression

Antimycin A results in increased expression of TACC3 mRNA

NCBI chr 4:1,721,521...1,745,171
Ensembl chr 4:1,712,858...1,745,171

G

TATA-box binding protein associated factor 7

increases expression

Antimycin A results in increased expression of TAF7 mRNA

NCBI chr 5:141,318,490...141,320,784
Ensembl chr 5:141,259,884...141,320,784

G

TATA-box binding protein associated factor 9

increases expression

Antimycin A results in increased expression of TAF9 mRNA

NCBI chr 5:69,364,743...69,369,824
Ensembl chr 5:69,362,026...69,370,013

G

transgelin

increases expression

Antimycin A results in increased expression of TAGLN mRNA

NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464

G

TAP binding protein

decreases expression

Antimycin A results in decreased expression of TAPBP mRNA

NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284

G

TAR (HIV-1) RNA binding protein 1

decreases expression

Antimycin A results in decreased expression of TARBP1 mRNA

NCBI chr 1:234,391,313...234,479,179
Ensembl chr 1:234,391,313...234,479,179

G

transcription elongation factor A like 4

decreases expression

Antimycin A results in decreased expression of TCEAL4 mRNA

NCBI chr X:103,576,231...103,587,729
Ensembl chr X:103,576,231...103,587,729

G

transcription elongation factor A like 9

increases expression

Antimycin A results in increased expression of TCEAL9 mRNA

NCBI chr X:103,356,506...103,358,462
Ensembl chr X:103,356,489...103,358,462

G

transcription factor 4

decreases expression

Antimycin A results in decreased expression of TCF4 mRNA

NCBI chr18:55,222,185...55,635,957
Ensembl chr18:55,222,185...55,664,787

G

T cell leukemia translocation altered

decreases expression

Antimycin A results in decreased expression of TCTA mRNA

NCBI chr 3:49,412,423...49,416,476
Ensembl chr 3:49,412,212...49,416,476

G

tectonic family member 1

decreases expression

Antimycin A results in decreased expression of TCTN1 mRNA

NCBI chr12:110,614,129...110,649,430
Ensembl chr12:110,614,027...110,663,431

G

transcription factor A, mitochondrial

decreases expression

Antimycin A results in decreased expression of TFAM mRNA

NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220

G

transcription factor AP-2 alpha

decreases expression

Antimycin A results in decreased expression of TFAP2A mRNA

NCBI chr 6:10,396,677...10,419,659
Ensembl chr 6:10,393,186...10,419,659

G

transcription factor Dp-1

decreases expression

Antimycin A results in decreased expression of TFDP1 mRNA

NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473

G

transcription factor EB

multiple interactions

[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]]

NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259

G

transforming growth factor beta 1

increases expression

Antimycin A results in increased expression of TGFB1 mRNA

NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922

G

transforming growth factor beta 3

decreases expression

Antimycin A results in decreased expression of TGFB3 mRNA

NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011

G

TCDD inducible poly(ADP-ribose) polymerase

increases expression

Antimycin A results in increased expression of TIPARP mRNA

NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770

G

TIMELESS interacting protein

increases expression

Antimycin A results in increased expression of TIPIN mRNA

NCBI chr15:66,336,191...66,386,717
Ensembl chr15:66,336,191...66,386,746

G

tousled like kinase 2

decreases expression

Antimycin A results in decreased expression of TLK2 mRNA

NCBI chr17:62,470,914...62,615,481
Ensembl chr17:62,458,658...62,615,481

G

TM2 domain containing 2

decreases expression

Antimycin A results in decreased expression of TM2D2 mRNA

NCBI chr 8:38,988,808...38,996,990
Ensembl chr 8:38,988,808...38,996,824

G

transmembrane 9 superfamily member 3

decreases expression

Antimycin A results in decreased expression of TM9SF3 mRNA

NCBI chr10:96,518,110...96,587,012
Ensembl chr10:96,518,110...96,587,452

G

transmembrane protein 185A

decreases expression

Antimycin A results in decreased expression of TMEM185A mRNA

NCBI chr X:149,596,556...149,631,792
Ensembl chr X:149,596,556...149,631,912

G

tenascin C

decreases expression

Antimycin A results in decreased expression of TNC mRNA

NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207

G

tumor necrosis factor

increases expression
multiple interactions

Antimycin A results in increased expression of TNF protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of TNF protein]; 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased expression of TNF protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of TNF protein]; Antimycin A inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; Antimycin A inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; Antimycin A inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; Antimycin A inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Antimycin A results in increased expression of and results in increased secretion of TNF protein; Cyclosporine inhibits the reaction [Antimycin A results in increased expression of and results in increased secretion of TNF protein]; sciadopitysin inhibits the reaction [Antimycin A results in increased expression of TNF protein]
Antimycin A inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Antimycin A promotes the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Antimycin A promotes the reaction [TNF protein results in increased expression of CXCL8 protein]

PMID:11264281 PMID:21381053 PMID:21910134 PMID:22549761 PMID:23624148 More...

NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336

G

TNF alpha induced protein 3

multiple interactions

Antimycin A inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]

NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314

G

TNF receptor superfamily member 10b

increases expression

Antimycin A results in increased expression of TNFRSF10B mRNA

NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031

G

TNF receptor superfamily member 11b

decreases expression

Antimycin A results in decreased expression of TNFRSF11B protein

NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885

G

TNF receptor superfamily member 12A

increases expression

Antimycin A results in increased expression of TNFRSF12A mRNA

NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383

G

TNF superfamily member 11

increases expression
multiple interactions

Antimycin A results in increased expression of TNFSF11 protein
23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased expression of TNFSF11 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Antimycin A results in increased expression of TNFSF11 protein]

PMID:21381053 PMID:21910134

NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013

G

TNF superfamily member 13b

increases expression

Antimycin A results in increased expression of TNFSF13B mRNA

NCBI chr13:108,269,629...108,308,484
Ensembl chr13:108,251,240...108,308,484

G

TNFAIP3 interacting protein 1

decreases expression

Antimycin A results in decreased expression of TNIP1 mRNA

NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577

G

tenascin XB

decreases expression

Antimycin A results in decreased expression of TNXB mRNA

NCBI chr 6:32,041,153...32,109,338
Ensembl chr 6:32,041,153...32,115,334

G

DNA topoisomerase II alpha

increases expression

Antimycin A results in increased expression of TOP2A mRNA

NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896

G

tumor protein p53

increases response to substance
increases acetylation
multiple interactions

TRP53 protein results in increased susceptibility to Antimycin A
Antimycin A results in increased acetylation of TRP53 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Antimycin A results in increased acetylation of TRP53 protein]; Resveratrol inhibits the reaction [Antimycin A results in increased acetylation of TRP53 protein]

NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546

G

tumor protein p53 inducible protein 3

increases expression

Antimycin A results in increased expression of TP53I3 mRNA

NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861

G

TPX2 microtubule nucleation factor

increases expression

Antimycin A results in increased expression of TPX2 mRNA

NCBI chr20:31,739,290...31,801,800
Ensembl chr20:31,739,271...31,801,805

G

tribbles pseudokinase 1

increases expression

Antimycin A results in increased expression of TRIB1 mRNA

NCBI chr 8:125,430,358...125,438,403
Ensembl chr 8:125,430,358...125,438,403

G

tribbles pseudokinase 3

increases expression

Antimycin A results in increased expression of TRIB3 mRNA

PMID:19304788 PMID:33512557

NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559

G

tripartite motif containing 13

decreases expression

Antimycin A results in decreased expression of TRIM13 mRNA

NCBI chr13:49,997,042...50,018,467
Ensembl chr13:49,995,888...50,020,481

G

thyroid hormone receptor interactor 12

decreases expression

Antimycin A results in decreased expression of TRIP12 mRNA

NCBI chr 2:229,763,837...229,923,186
Ensembl chr 2:229,763,837...229,923,239

G

transient receptor potential cation channel subfamily V member 1

decreases expression

Antimycin A results in decreased expression of TRPV1 mRNA

NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411

G

tumor susceptibility 101

decreases expression

Antimycin A results in decreased expression of TSG101 mRNA

NCBI chr11:18,480,311...18,526,942
Ensembl chr11:18,468,336...18,526,951

G

teashirt zinc finger homeobox 2

decreases expression

Antimycin A results in decreased expression of TSHZ2 mRNA

NCBI chr20:52,972,358...53,495,330
Ensembl chr20:52,972,358...53,495,330

G

tsukushi, small leucine rich proteoglycan

decreases expression

Antimycin A results in decreased expression of TSKU mRNA

NCBI chr11:76,782,280...76,798,144
Ensembl chr11:76,782,251...76,798,153

G

tetraspanin 3

decreases expression

Antimycin A results in decreased expression of TSPAN3 mRNA

NCBI chr15:77,041,404...77,071,109
Ensembl chr15:77,041,404...77,083,984

G

thiosulfate sulfurtransferase

decreases expression

Antimycin A results in decreased expression of TST mRNA

NCBI chr22:37,010,859...37,020,183
Ensembl chr22:37,010,859...37,020,183

G

tubulin beta 2A class IIa

decreases expression

Antimycin A results in decreased expression of TUBB2A mRNA

PMID:33512557 PMID:33770205

NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544

G

tubulin beta 2B class IIb

decreases expression

Antimycin A results in decreased expression of TUBB2B mRNA

NCBI chr 6:3,224,277...3,227,653
Ensembl chr 6:3,223,324...3,231,730

G

terminal uridylyl transferase 7

decreases expression

Antimycin A results in decreased expression of TUT7 mRNA

NCBI chr 9:86,287,733...86,354,410
Ensembl chr 9:86,287,733...86,354,454

G

thioredoxin domain containing 5

increases expression

Antimycin A results in increased expression of TXNDC5 mRNA

NCBI chr 6:7,881,517...7,910,788
Ensembl chr 6:7,881,517...7,910,788

G

thioredoxin interacting protein

decreases expression

Antimycin A results in decreased expression of TXNIP mRNA

NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579

G

thioredoxin reductase 1

increases expression

Antimycin A results in increased expression of TXNRD1 mRNA

NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307

G

thioredoxin reductase 2

increases expression

Antimycin A results in increased expression of TXNRD2 mRNA

NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820

G

thymidylate synthetase

increases expression

Antimycin A results in increased expression of TYMS mRNA

NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578

G

ubiquitin B

increases expression

Antimycin A results in increased expression of UBB mRNA

NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745

G

ubiquitin conjugating enzyme E2 C

increases expression

Antimycin A results in increased expression of UBE2C mRNA

NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957

G

ubiquitin conjugating enzyme E2 Q2

decreases expression

Antimycin A results in decreased expression of UBE2Q2 mRNA

NCBI chr15:75,843,447...75,901,078
Ensembl chr15:75,843,307...75,901,078

G

ubiquitin C-terminal hydrolase L1

decreases expression

Antimycin A results in decreased expression of UCHL1 mRNA

NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455

G

uncoupling protein 2

increases expression
decreases expression

Antimycin A results in increased expression of UCP2 protein
Antimycin A results in decreased expression of UCP2 mRNA; Antimycin A results in decreased expression of UCP2 protein

PMID:18082129 PMID:34302933

NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843

G

unc-51 like autophagy activating kinase 1

multiple interactions
increases expression

Antimycin A inhibits the reaction [Cycloheximide results in decreased expression of ULK1 protein]; Antimycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; Antimycin A promotes the reaction [ATG13 protein results in increased expression of ULK1 protein]; ATG13 protein promotes the reaction [Antimycin A results in increased expression of ULK1 protein]; Cycloheximide inhibits the reaction [Antimycin A results in increased expression of ULK1 protein]; Nitrogen deficiency inhibits the reaction [Antimycin A results in increased expression of ULK1 protein]
Antimycin A results in increased expression of ULK1 mRNA; Antimycin A results in increased expression of ULK1 protein

NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150

G

unc-50 inner nuclear membrane RNA binding protein

decreases expression

Antimycin A results in decreased expression of UNC50 mRNA

NCBI chr 2:98,608,589...98,618,515
Ensembl chr 2:98,608,579...98,618,515

G

ubiquinol-cytochrome c reductase complex assembly factor 3

decreases expression

Antimycin A results in decreased expression of UQCC3 mRNA

NCBI chr11:62,671,673...62,673,686
Ensembl chr11:62,670,273...62,673,686

G

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

decreases expression

Antimycin A results in decreased expression of UQCRFS1 mRNA

NCBI chr19:29,205,320...29,213,151
Ensembl chr19:29,205,320...29,213,151

G

UTP14A small subunit processome component

increases expression

Antimycin A results in increased expression of UTP14A mRNA

NCBI chr X:129,906,164...129,929,752
Ensembl chr X:129,906,121...129,929,761

G

urotensin 2

increases expression

Antimycin A results in increased expression of UTS2 mRNA

NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512

G

VAMP associated protein B and C

decreases expression

Antimycin A results in decreased expression of VAPB mRNA

PMID:33512557 PMID:34642769

NCBI chr20:58,389,229...58,451,101
Ensembl chr20:58,389,229...58,451,101

G

vav guanine nucleotide exchange factor 3

decreases expression

Antimycin A results in decreased expression of VAV3 mRNA

NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180

G

voltage dependent anion channel 1

decreases expression

Antimycin A results in decreased expression of VDAC1 mRNA

NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975

G

vascular endothelial growth factor A

decreases expression
multiple interactions
increases expression

Antimycin A results in decreased expression of VEGFA protein
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of VEGFA mRNA]

PMID:20116850 PMID:33512557 PMID:35430258

NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487

G

vestigial like family member 4

decreases expression

Antimycin A results in decreased expression of VGLL4 mRNA

NCBI chr 3:11,556,067...11,721,815
Ensembl chr 3:11,556,069...11,771,350

G

vimentin

increases expression

Antimycin A results in increased expression of VIM mRNA

NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593

G

vacuolar protein sorting 72 homolog

decreases expression

Antimycin A results in decreased expression of VPS72 mRNA

NCBI chr 1:151,176,304...151,190,197
Ensembl chr 1:151,176,304...151,195,321

G

tryptophanyl-tRNA synthetase 1

increases expression

Antimycin A results in increased expression of WARS1 mRNA

NCBI chr14:100,333,790...100,376,327
Ensembl chr14:100,333,790...100,376,805

G

WD repeat domain 43

increases expression

Antimycin A results in increased expression of WDR43 mRNA

NCBI chr 2:28,894,667...28,948,219
Ensembl chr 2:28,894,667...28,948,219

G

WD repeat domain 7

decreases expression

Antimycin A results in decreased expression of WDR7 mRNA

NCBI chr18:56,651,359...57,036,606
Ensembl chr18:56,651,343...57,029,811

G

WD and tetratricopeptide repeats 1

decreases expression

Antimycin A results in decreased expression of WDTC1 mRNA

NCBI chr 1:27,234,441...27,308,636
Ensembl chr 1:27,234,632...27,308,636

G

Wnt family member 7A

increases expression

Antimycin A results in increased expression of WNT7A mRNA

NCBI chr 3:13,816,258...13,880,071
Ensembl chr 3:13,816,258...13,880,071

G

X-box binding protein 1

increases expression

Antimycin A results in increased expression of XBP1 protein
Antimycin A results in increased expression of XBP1 mRNA

PMID:21337367 PMID:33512557

NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597

G

YES proto-oncogene 1, Src family tyrosine kinase

decreases expression

Antimycin A results in decreased expression of YES1 mRNA

NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

decreases expression

Antimycin A results in decreased expression of YWHAB mRNA

NCBI chr20:44,885,705...44,908,532
Ensembl chr20:44,885,702...44,908,532

G

zinc finger and BTB domain containing 21

increases expression

Antimycin A results in increased expression of ZBTB21 mRNA

NCBI chr21:41,986,831...42,010,360
Ensembl chr21:41,986,831...42,010,387

G

zinc finger and BTB domain containing 41

decreases expression

Antimycin A results in decreased expression of ZBTB41 mRNA

NCBI chr 1:197,153,682...197,201,293
Ensembl chr 1:197,153,682...197,201,293

G

zinc finger E-box binding homeobox 2

decreases expression

Antimycin A results in decreased expression of ZEB2 mRNA

NCBI chr 2:144,384,081...144,520,119
Ensembl chr 2:144,364,364...144,521,057

G

zinc finger AN1-type containing 2A

increases expression

Antimycin A results in increased expression of ZFAND2A mRNA

NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,151,903...1,160,759

G

zinc fingers and homeoboxes 1

decreases expression

Antimycin A results in decreased expression of ZHX1 mRNA

NCBI chr 8:123,248,456...123,275,541
Ensembl chr 8:123,248,451...123,275,541

G

zinc finger protein 383

increases expression

Antimycin A results in increased expression of ZNF383 mRNA

NCBI chr19:37,218,214...37,248,740
Ensembl chr19:37,217,926...37,248,740

G

zinc finger protein 469

increases expression

Antimycin A results in increased expression of ZNF469 mRNA

NCBI chr16:88,100,931...88,440,753
Ensembl chr16:88,382,959...88,440,757

G

zinc finger protein 589

decreases expression

Antimycin A results in decreased expression of ZNF589 mRNA

NCBI chr 3:48,241,104...48,270,990
Ensembl chr 3:48,241,100...48,299,253

G

Zn regulated GTPase metalloprotein activator 1E

decreases expression

Antimycin A results in decreased expression of ZNG1E mRNA

NCBI chr 9:65,652,979...65,734,041
Ensembl chr 9:65,668,805...65,734,041

G

Zn regulated GTPase metalloprotein activator 1F

decreases expression

Antimycin A results in decreased expression of ZNG1F mRNA

NCBI chr 9:41,131,309...41,205,735
Ensembl chr 9:41,131,306...41,199,261
Ensembl chr 9:41,131,306...41,199,261

G

zinc finger RANBP2-type containing 2

increases expression

Antimycin A results in increased expression of ZRANB2 mRNA

NCBI chr 1:71,063,291...71,081,035
Ensembl chr 1:71,063,291...71,081,289

riddelliine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1

increases expression

riddelliine results in increased expression of ABCB1 mRNA; riddelliine results in increased expression of ABCB1A mRNA

PMID:18047722 PMID:18047727

NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323

G

ATP binding cassette subfamily B member 9

decreases expression

riddelliine results in decreased expression of ABCB9 mRNA

NCBI chr12:122,918,610...122,975,114
Ensembl chr12:122,920,951...122,981,649

G

ATP binding cassette subfamily C member 3

increases expression

riddelliine results in increased expression of ABCC3 mRNA

PMID:18047722 PMID:18047727

NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253

G

ATP binding cassette subfamily C member 8

decreases expression

riddelliine results in decreased expression of ABCC8 mRNA

PMID:18047722 PMID:18047727

NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894

G

ATP binding cassette subfamily C member 9

decreases expression

riddelliine results in decreased expression of ABCC9 mRNA

NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543

G

adrenomedullin

decreases expression

riddelliine results in decreased expression of ADM mRNA

NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397

G

aryl hydrocarbon receptor

increases expression

riddelliine results in increased expression of AHR mRNA

NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152

G

anaphase promoting complex subunit 1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ANAPC1 mRNA

NCBI chr 2:111,766,231...111,884,193
Ensembl chr 2:111,611,639...111,884,690

G

AT-rich interaction domain 2

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ARID2 mRNA

NCBI chr12:45,729,706...45,908,037
Ensembl chr12:45,729,706...45,908,040

G

ATPase 13A5

decreases expression

riddelliine results in decreased expression of ATP13A5 mRNA

NCBI chr 3:193,274,789...193,378,753
Ensembl chr 3:193,274,789...193,378,820

G

ATR interacting protein

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ATRIP mRNA

NCBI chr 3:48,446,737...48,467,645
Ensembl chr 3:48,446,710...48,467,645

G

aurora kinase A

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of AURKA mRNA

NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337

G

BRISC and BRCA1 A complex member 2

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of BABAM2 mRNA

NCBI chr 2:27,888,709...28,338,901
Ensembl chr 2:27,889,941...28,338,901

G

BRCA1 associated RING domain 1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BARD1 mRNA

NCBI chr 2:214,725,646...214,809,683
Ensembl chr 2:214,725,646...214,809,683

G

BLM RecQ like helicase

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BLM mRNA

NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166

G

BORA aurora kinase A activator

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BORA mRNA

NCBI chr13:72,727,923...72,756,196
Ensembl chr13:72,727,749...72,756,198

G

BRCA1 DNA repair associated

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA1 mRNA

NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245

G

BRCA2 DNA repair associated

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA2 mRNA

NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268

G

BRCA1 interacting DNA helicase 1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRIP1 mRNA

NCBI chr17:61,679,139...61,863,528
Ensembl chr17:61,679,139...61,863,559

G

cyclin B1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB1 mRNA

NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245

G

cyclin B2

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB2 mRNA

NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045

G

cell division cycle 20

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC20 mRNA

NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203

G

cell division cycle 23

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC23 mRNA

NCBI chr 5:138,187,650...138,213,323
Ensembl chr 5:138,187,650...138,213,343

G

cell division cycle 25A

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25A mRNA

NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417

G

cell division cycle 25B

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25B mRNA

NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121

G

cell division cycle 25C

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25C mRNA

NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355

G

cyclin dependent kinase 1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK1 mRNA

NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852

G

cyclin dependent kinase 2

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK2 mRNA

NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789

G

cyclin dependent kinase inhibitor 1A

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of CDKN1A mRNA

NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397

G

carboxylesterase 2

increases expression

riddelliine results in increased expression of CES2 mRNA

NCBI chr16:66,934,471...66,945,096
Ensembl chr16:66,934,444...66,945,096

G

checkpoint kinase 1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CHEK1 mRNA

NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255

G

claspin

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CLSPN mRNA

NCBI chr 1:35,720,213...35,769,978
Ensembl chr 1:35,720,218...35,769,978

G

C-X-C motif chemokine receptor 1

increases expression

riddelliine results in increased expression of CXCR1 mRNA

NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962

G

cytochrome P450 family 26 subfamily A member 1

increases expression

riddelliine results in increased expression of CYP26A1 mRNA

NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885

G

cytochrome P450 family 2 subfamily C member 18

decreases expression

riddelliine results in decreased expression of CYP2C mRNA

PMID:18047722 PMID:18047727

NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190

G

cytochrome P450 family 2 subfamily E member 1

increases expression

riddelliine results in increased expression of CYP2E1 mRNA

PMID:18047722 PMID:18047727

NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220

G

cytochrome P450 family 3 subfamily A member 4

multiple interactions
increases response to substance
decreases expression
increases metabolic processing

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ANAPC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ARID2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ATRIP mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of AURKA mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BARD1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BLM mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BORA mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRIP1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC20 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC23 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25B mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25C mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CHEK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CLSPN mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F5 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F8 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ESPL1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCA mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCB mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCC mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCD2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FBXO5 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of KIF11 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of KIF23 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MDC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MRE11 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MSH2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MSH6 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of NBN mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PBRM1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PHF10 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PKMYT1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PLK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PLK4 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of POU2F1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPM1L mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R1B mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R2A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PRC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PTTG1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RAD1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RAD21 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBBP8 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBL1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBL2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC3 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC4 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC5 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RPA1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of SMARCC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of SMC3 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of STAG2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TLK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TOP2A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TOPBP1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of WEE1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of BABAM2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of CDKN1A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of GADD45A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PLK2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PLK3 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PPP2CB mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of SMARCA2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of STAT1 mRNA
CYP3A4 protein results in increased susceptibility to riddelliine
riddelliine results in decreased expression of CYP3A2 mRNA

PMID:18047727 PMID:32910235 PMID:33884520

NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248

G

cytochrome P450 family 3 subfamily A member 43

decreases expression

riddelliine results in decreased expression of CYP3A18 mRNA

NCBI chr 7:99,828,013...99,866,093
Ensembl chr 7:99,828,013...99,866,093

G

cytochrome P450 family 3 subfamily A member 5

increases expression

riddelliine results in increased expression of CYP3A9 mRNA

NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996

G

E2F transcription factor 1

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F1 mRNA

NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385

G

E2F transcription factor 5

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F5 mRNA

NCBI chr 8:85,177,154...85,214,518
Ensembl chr 8:85,177,154...85,217,158

G

E2F transcription factor 8

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F8 mRNA

NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620

G

early growth response 1

increases expression

riddelliine results in increased expression of EGR1 mRNA

NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

decreases expression

riddelliine results in decreased expression of ENPP2 mRNA

NCBI chr 8:119,557,086...119,673,390
Ensembl chr 8:119,557,086...119,673,453

G

extra spindle pole bodies like 1, separase

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ESPL1 mRNA

NCBI chr12:53,268,299...53,293,638
Ensembl chr12:53,268,299...53,293,638

G

F11 receptor

decreases expression

riddelliine results in decreased expression of F11R mRNA

NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175

G

coagulation factor III, tissue factor

decreases expression

riddelliine results in decreased expression of F3 mRNA

NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759

G

coagulation factor VII

increases expression

riddelliine results in increased expression of F7 mRNA

NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685

G

FA complementation group A

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCA mRNA

NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977

G

FA complementation group B

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCB mRNA

NCBI chr X:14,689,524...14,873,069
Ensembl chr X:14,690,388...14,873,255

G

FA complementation group C

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCC mRNA

NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796

G

FA complementation group D2

multiple interactions

[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCD2 mRNA

NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932