(R,R)-chrysanthemal - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	(R,R)-chrysanthemal	go back to main search page
Accession:	CHEBI:143899	browse the term
Definition:	An aldehyde resulting from the formal oxidation of the hydroxy group of (R,R)-chrysanthemol.
Synonyms:	exact_synonym:	(1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarbaldehyde
	related_synonym:	(1R,3R)-chrysanthemal; Formula=C10H16O; InChI=1S/C10H16O/c1-7(2)5-8-9(6-11)10(8,3)4/h5-6,8-9H,1-4H3/t8-,9-/m1/s1; InChIKey=NQLKPDBZZUIQGM-RKDXNWHRSA-N; SMILES=C1([C@@H]([C@H]1C=C(C)C)C=O)(C)C
	xref:	PMID:29122986

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Genes (350)

(+)-trans-(S)-allethrin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

decreases activity

ISO

bioallethrin results in decreased activity of ACE protein

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

ISO

Vitamin E inhibits the reaction [bioallethrin results in increased expression of BAX protein]

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

caspase 3

increases cleavage
multiple interactions

ISO

bioallethrin results in increased cleavage of CASP3 protein
Vitamin E inhibits the reaction [bioallethrin results in increased cleavage of CASP3 protein]

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 9

multiple interactions
increases cleavage

ISO

Vitamin E inhibits the reaction [bioallethrin results in increased cleavage of CASP9 protein]

Ensembl chr 5:159,391,188...159,409,648

G

catalase

decreases activity

ISO

bioallethrin results in decreased activity of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

carboxylesterase 1D

increases metabolic processing

ISO

CES1 protein results in increased metabolism of bioallethrin

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449

G

cholinergic receptor, muscarinic 4

multiple interactions

ISO

[DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA

NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases metabolic processing
increases expression

ISO

CYP3A4 protein results in increased metabolism of bioallethrin
bioallethrin results in increased expression of CYP3A4 mRNA

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

glyoxalase 1

increases activity

ISO

bioallethrin results in increased activity of GLO1 protein

NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,665,061...8,683,191

G

glutathione-disulfide reductase

decreases activity

ISO

bioallethrin results in decreased activity of GSR protein

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

heme oxygenase 1

increases expression
multiple interactions

ISO

bioallethrin results in increased expression of HMOX1 protein
[Vitamin E co-treated with bioallethrin] results in increased expression of HMOX1 protein

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

interferon gamma

multiple interactions
decreases expression
affects expression

ISO

[bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein
bioallethrin results in decreased expression of IFNG mRNA
bioallethrin affects the expression of IFNG protein

PMID:9860237 PMID:10414782 PMID:12755381

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interleukin 4

multiple interactions
affects expression

ISO

[bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein
bioallethrin affects the expression of IL4 protein

PMID:9860237 PMID:10414782

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549

G

NFE2 like bZIP transcription factor 2

increases expression
multiple interactions

ISO

bioallethrin results in increased expression of NFE2L2 protein
Vitamin E inhibits the reaction [bioallethrin results in increased expression of NFE2L2 protein]

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions

ISO

bioallethrin results in increased expression of NQO1 protein
[Vitamin E co-treated with bioallethrin] results in increased expression of NQO1 protein

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group I, member 2

increases activity

ISO
EXP

bioallethrin results in increased activity of NR1I2 protein

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

G

sodium voltage-gated channel alpha subunit 10

affects activity

EXP

bioallethrin affects the activity of SCN10A protein

NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:128,228,424...128,340,298

G

sodium voltage-gated channel beta subunit 1

multiple interactions

EXP

bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium]

NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:95,481,298...95,491,197

G

sodium voltage-gated channel beta subunit 2

multiple interactions

EXP

bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium]

NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:54,322,383...54,334,519

G

sodium voltage-gated channel alpha subunit 8

multiple interactions

EXP

bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium]

NCBI chr 7:133,860,901...134,034,809
Ensembl chr 7:133,861,227...134,030,026

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

catalase

decreases expression

EXP

imiprothrin results in decreased expression of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression

EXP

imiprothrin results in increased expression of CYP1A2 mRNA

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

glutamic--pyruvic transaminase

increases expression

EXP

imiprothrin results in increased expression of GPT protein

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

metallothionein 1A

increases expression

EXP

imiprothrin results in increased expression of MT1 mRNA

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

EXP

Pyrethrins results in decreased expression of A2M protein

NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868

G

ATP binding cassette subfamily B member 6

decreases expression

EXP

Pyrethrins results in decreased expression of ABCB6 protein

NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526

G

ATP binding cassette subfamily G member 5

decreases expression

EXP

Pyrethrins results in decreased expression of ABCG5 protein

NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

increases expression

ISO

Pyrethrins results in increased expression of ABL1 mRNA

NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846

G

atypical chemokine receptor 3

decreases expression

EXP

Pyrethrins results in decreased expression of ACKR3 protein

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

acyl-CoA synthetase bubblegum family member 2

decreases expression

EXP

Pyrethrins results in decreased expression of ACSBG2 protein

NCBI chr 9:1,770,971...1,802,635
Ensembl chr 9:1,770,972...1,801,655

G

actinin, alpha 1

decreases expression

EXP

Pyrethrins results in decreased expression of ACTN1 protein

NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172

G

ADAM metallopeptidase with thrombospondin type 1 motif, 7

increases expression

EXP

Pyrethrins results in increased expression of ADAMTS7 protein

NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132

G

adenylate cyclase 2

decreases expression

EXP

Pyrethrins results in decreased expression of ADCY2 protein

NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645

G

adducin 1

decreases expression

EXP

Pyrethrins results in decreased expression of ADD1 protein

NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732

G

AE binding protein 1

decreases expression

EXP

Pyrethrins results in decreased expression of AEBP1 protein

NCBI chr14:84,951,577...84,962,840
Ensembl chr14:84,952,822...84,962,843

G

apoptosis inducing factor, mitochondria associated 1

decreases expression

ISO

Pyrethrins results in decreased expression of AIFM1 mRNA

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237

G

AKT serine/threonine kinase 1

decreases expression

ISO

Pyrethrins results in decreased expression of AKT1 mRNA

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

arachidonate 15-lipoxygenase

decreases expression

EXP

Pyrethrins results in decreased expression of ALOX15 protein

NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723

G

anti-Mullerian hormone

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of AMH mRNA
Pyrethrins affects the expression of AMH mRNA

PMID:34896426 PMID:36053783

NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:9,557,451...9,559,867

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

EXP

Pyrethrins results in decreased expression of ANKH protein

NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699

G

annexin A6

decreases expression

EXP

Pyrethrins results in decreased expression of ANXA6 protein

NCBI chr10:39,602,106...39,657,183
Ensembl chr10:39,602,106...39,657,359

G

apoptotic peptidase activating factor 1

decreases expression

ISO

Pyrethrins results in decreased expression of APAF1 mRNA

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772

G

androgen receptor

decreases expression

EXP

Pyrethrins results in decreased expression of AR mRNA

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

armadillo repeat containing 5

decreases expression

EXP

Pyrethrins results in decreased expression of ARMC5 protein

NCBI chr 1:192,250,580...192,257,347
Ensembl chr 1:192,249,939...192,257,348

G

actin related protein 2/3 complex, subunit 1B

affects expression

EXP

Pyrethrins affects the expression of ARPC1B protein

NCBI chr12:14,595,939...14,609,501
Ensembl chr12:14,595,678...14,609,504

G

atrophin 1

decreases expression

EXP

Pyrethrins results in decreased expression of ATN1 protein

NCBI chr 4:159,240,573...159,254,378
Ensembl chr 4:159,237,562...159,254,418

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

decreases expression

EXP

Pyrethrins results in decreased expression of ATP2A1 protein

NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:190,457,198...190,475,423

G

advillin

decreases expression

EXP

Pyrethrins results in decreased expression of AVIL protein

NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436

G

BCL2-associated agonist of cell death

decreases expression

ISO

Pyrethrins results in decreased expression of BAD mRNA

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034

G

BAG cochaperone 1

decreases expression

ISO

Pyrethrins results in decreased expression of BAG1 mRNA

NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161

G

BAG cochaperone 3

increases expression

ISO

Pyrethrins results in increased expression of BAG3 mRNA

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280

G

BCL2-antagonist/killer 1

decreases expression

ISO

Pyrethrins results in decreased expression of BAK1 mRNA

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974

G

BCL2 associated X, apoptosis regulator

affects expression
decreases expression

ISO
EXP

Pyrethrins affects the expression of BAX protein
Pyrethrins results in decreased expression of BAX mRNA

PMID:27939866 PMID:34896426 PMID:35321623 PMID:36053783

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

brevican

decreases expression

EXP

Pyrethrins results in decreased expression of BCAN protein

NCBI chr 2:175,752,333...175,765,766
Ensembl chr 2:175,752,336...175,765,314

G

BCL2, apoptosis regulator

affects expression
increases expression

ISO
EXP

Pyrethrins affects the expression of BCL2 protein
Pyrethrins results in increased expression of BCL2 mRNA

PMID:27939866 PMID:34896426 PMID:36053783

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

Bcl2-like 1

increases expression

ISO

Pyrethrins results in increased expression of BCL2L1 mRNA

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 11

increases expression

ISO

Pyrethrins results in increased expression of BCL2L11 mRNA

NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695

G

brain-derived neurotrophic factor

multiple interactions

ISO

Pyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA]

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

BH3 interacting domain death agonist

decreases expression

ISO

Pyrethrins results in decreased expression of BID mRNA

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275

G

BCL2-interacting killer

increases expression

ISO

Pyrethrins results in increased expression of BIK mRNA

NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317

G

baculoviral IAP repeat-containing 5

decreases expression

ISO

Pyrethrins results in decreased expression of BIRC5 mRNA

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

BCL2 interacting protein 3

increases expression
decreases expression

ISO

Pyrethrins results in increased expression of BNIP3 mRNA
Pyrethrins results in decreased expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962

G

BCL2 interacting protein 3 like

decreases expression

ISO

Pyrethrins results in decreased expression of BNIP3L mRNA

NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282

G

BRCA1, DNA repair associated

decreases expression

EXP

Pyrethrins results in decreased expression of BRCA1 protein

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

bromodomain testis associated

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of BRDT protein
Pyrethrins affects the expression of BRDT mRNA

NCBI chr14:2,532,275...2,590,780
Ensembl chr14:2,532,275...2,590,760

G

BMP/retinoic acid inducible neural specific 3

decreases expression

EXP

Pyrethrins results in decreased expression of BRINP3 protein

NCBI chr13:60,964,127...61,397,044
Ensembl chr13:60,966,100...61,397,039

G

calcium voltage-gated channel subunit alpha1 C

decreases expression

EXP

Pyrethrins results in decreased expression of CACNA1C protein

NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762

G

calcium voltage-gated channel subunit alpha1 S

decreases expression

EXP

Pyrethrins results in decreased expression of CACNA1S protein

NCBI chr13:50,045,668...50,115,903
Ensembl chr13:50,045,668...50,115,903

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

decreases expression

EXP

Pyrethrins results in decreased expression of CACNA2D1 protein

NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147

G

calcium/calmodulin-dependent protein kinase kinase 1

affects expression

EXP

Pyrethrins affects the expression of CAMKK1 protein

NCBI chr10:58,135,872...58,159,023
Ensembl chr10:58,135,915...58,159,010

G

calmodulin regulated spectrin-associated protein 1

increases expression

EXP

Pyrethrins results in increased expression of CAMSAP1 protein

NCBI chr 3:29,144,318...29,206,382
Ensembl chr 3:29,144,318...29,204,184

G

capping protein regulator and myosin 1 linker 3

decreases expression

EXP

Pyrethrins results in decreased expression of CARMIL3 protein

NCBI chr15:32,948,228...32,965,829
Ensembl chr15:32,948,856...32,965,811

G

caspase 1

decreases expression

ISO

Pyrethrins results in decreased expression of CASP1 mRNA

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 14

decreases expression

ISO

Pyrethrins results in decreased expression of CASP14 mRNA

NCBI chr 7:11,577,315...11,583,987
Ensembl chr 7:11,580,339...11,583,171

G

caspase 2

decreases expression

ISO

Pyrethrins results in decreased expression of CASP2 mRNA

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022

G

caspase 3

increases activity
affects expression
increases expression

ISO
EXP

Pyrethrins results in increased activity of CASP3 protein
Pyrethrins affects the expression of CASP3 mRNA
Pyrethrins results in increased expression of CASP3 mRNA

PMID:27939866 PMID:34896426 PMID:35321623

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 4

increases expression

ISO

Pyrethrins results in increased expression of CASP4 mRNA

NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727

G

caspase 6

decreases expression

ISO

Pyrethrins results in decreased expression of CASP6 mRNA

NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726

G

caspase 9

increases activity
increases expression

ISO
EXP

Pyrethrins results in increased activity of CASP9 protein
Pyrethrins results in increased expression of CASP9 mRNA

PMID:27939866 PMID:36053783

Ensembl chr 5:159,391,188...159,409,648

G

catalase

increases activity

EXP

Pyrethrins results in increased activity of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

coiled-coil and C2 domain containing 1A

decreases expression

EXP

Pyrethrins results in decreased expression of CC2D1A protein

NCBI chr19:40,916,587...40,931,702
Ensembl chr19:40,916,532...40,931,701

G

cellular communication network factor 1

decreases expression

EXP

Pyrethrins results in decreased expression of CCN1 protein

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

CD27 molecule

decreases expression

ISO

Pyrethrins results in decreased expression of CD27 mRNA

NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823

G

CD40 molecule

decreases expression

ISO

Pyrethrins results in decreased expression of CD40 mRNA

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

CD40 ligand

decreases expression

ISO

Pyrethrins results in decreased expression of CD40LG mRNA

NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475

G

CD9 molecule

affects expression

EXP

Pyrethrins affects the expression of CD9 mRNA

NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444

G

cadherin 22

decreases expression

EXP

Pyrethrins results in decreased expression of CDH22 protein

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142

G

CDK5 regulatory subunit associated protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of CDK5RAP2 protein

NCBI chr 5:88,807,402...88,976,005
Ensembl chr 5:88,807,402...88,976,069

G

CASP8 and FADD-like apoptosis regulator

increases expression

ISO

Pyrethrins results in increased expression of CFLAR mRNA

NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434

G

CF transmembrane conductance regulator

decreases expression

EXP

Pyrethrins results in decreased expression of CFTR protein

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643

G

class II, major histocompatibility complex, transactivator

decreases expression

EXP

Pyrethrins results in decreased expression of CIITA mRNA

PMID:34896426 PMID:36053783

NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342

G

contactin 3

decreases expression

EXP

Pyrethrins results in decreased expression of CNTN3 protein

NCBI chr 4:134,841,268...135,214,460
Ensembl chr 4:136,398,572...136,770,717

G

collagen type XXVII alpha 1 chain

decreases expression

EXP

Pyrethrins results in decreased expression of COL27A1 protein

NCBI chr 5:81,662,822...81,781,502
Ensembl chr 5:81,661,685...81,781,502

G

collectin sub-family member 12

decreases expression

EXP

Pyrethrins results in decreased expression of COLEC12 protein

NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297

G

COP9 signalosome subunit 2

decreases expression

EXP

Pyrethrins results in decreased expression of COPS2 protein

NCBI chr 3:133,537,729...133,563,493
Ensembl chr 3:133,537,732...133,563,369

G

cAMP responsive element binding protein 1

affects expression

EXP

Pyrethrins affects the expression of CREB1 mRNA

NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339

G

CREB binding protein

decreases expression

EXP

Pyrethrins results in decreased expression of CREBBP mRNA

NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266

G

cAMP responsive element modulator

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of CREM mRNA
Pyrethrins affects the expression of CREM mRNA

PMID:34896426 PMID:36053783

NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160

G

cytochrome c, somatic

decreases expression

ISO

Pyrethrins results in decreased expression of CYCS mRNA

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression

EXP

Pyrethrins results in increased expression of CYP11A1 mRNA

PMID:34896426 PMID:36053783

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression
affects expression
decreases expression

EXP

Pyrethrins results in increased expression of CYP17A1 mRNA
Pyrethrins affects the expression of CYP17A1 mRNA
Pyrethrins results in decreased expression of CYP17A1 protein

PMID:34896426 PMID:36053783

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974

G

cytochrome P450, family 2, subfamily b, polypeptide 1

increases expression

EXP

Pyrethrins results in increased expression of CYP2B1 mRNA

NCBI chr 1:90,646,098...90,669,762

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression

EXP

Pyrethrins results in increased expression of CYP2B2 mRNA

NCBI chr 1:90,722,243...90,736,272

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression

ISO

Pyrethrins results in increased expression of CYP2B6 mRNA

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression

ISO

Pyrethrins results in increased expression of CYP3A4 mRNA

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

cytochrome P450, family 4, subfamily f, polypeptide 4

decreases expression

EXP

Pyrethrins results in decreased expression of CYP4F4 protein

NCBI chr 7:12,367,711...12,384,010
Ensembl chr 7:12,367,660...12,384,010

G

death associated protein kinase 1

decreases expression

ISO

Pyrethrins results in decreased expression of DAPK1 mRNA

NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581

G

DAZ associated protein 1

affects expression

EXP

Pyrethrins affects the expression of DAZAP1 mRNA

NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:10,074,849...10,095,599

G

discoidin domain receptor tyrosine kinase 1

decreases expression

EXP

Pyrethrins results in decreased expression of DDR1 protein

NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,050,375...3,069,276

G

DEAD-box helicase 25

affects expression

EXP

Pyrethrins affects the expression of DDX25 mRNA

NCBI chr 8:42,152,046...42,168,635
Ensembl chr 8:42,152,047...42,168,080

G

DEAD box helicase 3, Y-linked

decreases expression

EXP

Pyrethrins results in decreased expression of DDX3Y mRNA

NCBI chr Y:1,190,042...1,210,699
Ensembl chr Y:1,191,242...1,210,650

G

DEAD-box helicase 46

decreases expression

EXP

Pyrethrins results in decreased expression of DDX46 protein

NCBI chr17:8,947,237...8,993,705
Ensembl chr17:8,947,237...8,990,247

G

DNA fragmentation factor subunit alpha

increases expression

ISO

Pyrethrins results in increased expression of DFFA mRNA

NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728

G

DExH-box helicase 30

decreases expression

EXP

Pyrethrins results in decreased expression of DHX30 protein

NCBI chr 8:118,943,186...118,975,319
Ensembl chr 8:118,943,187...118,975,592

G

discs large MAGUK scaffold protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of DLG2 protein

NCBI chr 1:153,864,545...155,916,238
Ensembl chr 1:153,865,299...155,916,215

G

dihydrolipoamide S-succinyltransferase

decreases expression

EXP

Pyrethrins results in decreased expression of DLST protein

NCBI chr 6:110,489,576...110,512,841
Ensembl chr 6:110,489,392...110,514,357

G

DNA methyltransferase 3 alpha

increases expression

EXP

Pyrethrins results in increased expression of DNMT3A mRNA

PMID:34896426 PMID:36053783

NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970

G

DNA methyltransferase 3 beta

affects expression

EXP

Pyrethrins affects the expression of DNMT3B mRNA

NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313

G

dual oxidase 2

decreases expression

EXP

Pyrethrins results in decreased expression of DUOX2 protein

NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203

G

endothelin converting enzyme-like 1

decreases expression

EXP

Pyrethrins results in decreased expression of ECEL1 protein

NCBI chr 9:95,267,417...95,276,508
Ensembl chr 9:95,264,618...95,274,575

G

elaC ribonuclease Z 2

decreases expression

EXP

Pyrethrins results in decreased expression of ELAC2 protein

NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069

G

E1A binding protein p300

decreases expression

EXP

Pyrethrins results in decreased expression of EP300 mRNA

PMID:34896426 PMID:36053783

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

Eph receptor A3

decreases expression

EXP

Pyrethrins results in decreased expression of EPHA3 protein

NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425

G

Eph receptor A6

decreases expression

EXP

Pyrethrins results in decreased expression of EPHA6 protein

NCBI chr11:53,226,784...54,178,120
Ensembl chr11:53,226,954...54,166,987

G

erb-b2 receptor tyrosine kinase 3

increases expression

EXP

Pyrethrins results in increased expression of ERBB3 protein

NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120

G

ELKS/RAB6-interacting/CAST family member 2

decreases expression

EXP

Pyrethrins results in decreased expression of ERC2 protein

NCBI chr16:2,819,399...3,680,258
Ensembl chr16:2,819,512...3,680,258

G

ERCC excision repair 3, TFIIH core complex helicase subunit

decreases expression

EXP

Pyrethrins results in decreased expression of ERCC3 protein

NCBI chr18:24,157,831...24,188,543
Ensembl chr18:24,148,084...24,190,898

G

endothelial cell-specific molecule 1

decreases expression

EXP

Pyrethrins results in decreased expression of ESM1 protein

NCBI chr 2:46,609,253...46,617,991
Ensembl chr 2:46,609,204...46,617,990

G

exocyst complex component 3

decreases expression

EXP

Pyrethrins results in decreased expression of EXOC3 protein

NCBI chr 1:30,919,871...30,950,624

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

increases expression
decreases expression

EXP

Pyrethrins results in increased expression of EZH2 mRNA
Pyrethrins results in decreased expression of EZH2 mRNA

PMID:34896426 PMID:36053783

NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183

G

Fas associated via death domain

decreases expression

ISO

Pyrethrins results in decreased expression of FADD mRNA

NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases expression

EXP

Pyrethrins results in decreased expression of FARP1 protein

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147

G

Fas cell surface death receptor

decreases expression

ISO

Pyrethrins results in decreased expression of FAS mRNA

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

Fas ligand

decreases expression

ISO

Pyrethrins results in decreased expression of FASLG mRNA

NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503

G

fibulin 5

decreases expression

EXP

Pyrethrins results in decreased expression of FBLN5 protein

NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296

G

fem-1 homolog B

increases expression

EXP

Pyrethrins results in increased expression of FEM1B protein

NCBI chr 8:72,160,722...72,173,996
Ensembl chr 8:72,160,722...72,173,996

G

four and a half LIM domains 5

decreases expression

EXP

Pyrethrins results in decreased expression of FHL5 protein

NCBI chr 5:38,907,941...38,956,759
Ensembl chr 5:43,704,498...43,753,102

G

Fms related receptor tyrosine kinase 1

decreases expression

EXP

Pyrethrins results in decreased expression of FLT1 protein

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

Fms related receptor tyrosine kinase 4

decreases expression

EXP

Pyrethrins results in decreased expression of FLT4 protein

NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions

ISO

Pyrethrins inhibits the reaction [Potassium results in increased expression of FOS mRNA]

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

follicle stimulating hormone subunit beta

increases expression

EXP

Pyrethrins results in increased expression of FSHB protein

PMID:34896426 PMID:36053783

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

follicle stimulating hormone receptor

decreases expression
increases expression

EXP

Pyrethrins results in decreased expression of FSHR mRNA
Pyrethrins results in increased expression of FSHR mRNA

PMID:34896426 PMID:36053783

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288

G

growth arrest and DNA-damage-inducible, alpha

increases expression

ISO

Pyrethrins results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

glycyl-tRNA synthetase 1

decreases expression

EXP

Pyrethrins results in decreased expression of GARS1 protein

NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876

G

GATA binding protein 4

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of GATA4 mRNA
Pyrethrins affects the expression of GATA4 mRNA

PMID:34896426 PMID:36053783

NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609

G

GC, vitamin D binding protein

decreases expression

EXP

Pyrethrins results in decreased expression of GC protein

NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

EXP

Pyrethrins results in decreased expression of GCLC protein

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glial cell derived neurotrophic factor

affects expression

EXP

Pyrethrins affects the expression of GDNF mRNA

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

GDNF family receptor alpha 1

decreases expression

EXP

Pyrethrins results in decreased expression of GFRA1 mRNA

NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501

G

GTPase, IMAP family member 8

decreases expression

EXP

Pyrethrins results in decreased expression of GIMAP8 protein

NCBI chr 4:78,931,003...78,942,491
Ensembl chr 4:78,931,029...78,942,488

G

G protein nucleolar 1

decreases expression

EXP

Pyrethrins results in decreased expression of GNL1 protein

NCBI chr20:2,783,130...2,792,115
Ensembl chr20:2,787,940...2,797,577

G

gonadotropin releasing hormone 1

increases expression

EXP

Pyrethrins results in increased expression of GNRH1 protein

NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977
Ensembl chr15:46,148,301...46,148,977

G

gephyrin

decreases expression

EXP

Pyrethrins results in decreased expression of GPHN protein

NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:102,687,423...103,216,674

G

glutamic--pyruvic transaminase

affects activity

EXP

Pyrethrins affects the activity of GPT protein

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutamate ionotropic receptor AMPA type subunit 3

decreases expression

EXP

Pyrethrins results in decreased expression of GRIA3 protein

NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679

G

glutamate ionotropic receptor kainate type subunit 5

decreases expression

EXP

Pyrethrins results in decreased expression of GRIK5 protein

NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:89,733,741...89,794,962

G

glutamate metabotropic receptor 1

decreases expression

EXP

Pyrethrins results in decreased expression of GRM1 protein

NCBI chr 1:6,878,542...7,273,447
Ensembl chr 1:6,878,545...7,273,443

G

glutamate metabotropic receptor 5

decreases expression

EXP

Pyrethrins results in decreased expression of GRM5 protein

NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:150,733,678...151,296,649

G

granulin precursor

decreases expression

EXP

Pyrethrins results in decreased expression of GRN protein

NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936

G

general transcription factor II I

decreases expression

EXP

Pyrethrins results in decreased expression of GTF2I protein

NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677

G

guanylate cyclase 2E

decreases expression

EXP

Pyrethrins results in decreased expression of GUCY2E protein

NCBI chr10:54,453,753...54,478,639
Ensembl chr10:54,457,844...54,472,898

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

EXP

Pyrethrins results in decreased expression of HADHA protein

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

histone deacetylase 1

increases expression

EXP

Pyrethrins results in increased expression of HDAC1 mRNA

NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387

G

histone deacetylase 10

decreases expression

EXP

Pyrethrins results in decreased expression of HDAC10 mRNA

NCBI chr 7:122,078,768...122,084,457
Ensembl chr 7:122,078,768...122,083,870

G

histone deacetylase 4

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of HDAC4 mRNA
Pyrethrins affects the expression of HDAC4 mRNA

PMID:34896426 PMID:36053783

NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:99,955,116...100,197,637

G

histidine decarboxylase

affects expression

EXP

Pyrethrins affects the expression of HDC mRNA

NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711

G

hypoxia inducible factor 1 subunit alpha

increases expression

EXP

Pyrethrins results in increased expression of HIF1A mRNA

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

hypoxia inducible factor 3 subunit alpha

decreases expression

EXP

Pyrethrins results in decreased expression of HIF3A protein

NCBI chr 1:86,846,196...86,878,527
Ensembl chr 1:86,850,554...86,877,838

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression
affects expression

EXP

Pyrethrins results in increased expression of HMGCR mRNA
Pyrethrins affects the expression of HMGCR mRNA

PMID:34896426 PMID:36053783

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression
affects expression

EXP

Pyrethrins results in increased expression of HMGCS1 mRNA
Pyrethrins affects the expression of HMGCS1 mRNA

PMID:34896426 PMID:36053783

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

heme oxygenase 1

affects expression

EXP

Pyrethrins affects the expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heterochromatin protein 1, binding protein 3

affects expression

EXP

Pyrethrins affects the expression of HP1BP3 mRNA

NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:155,719,115...155,746,325

G

harakiri, BCL2 interacting protein

increases expression

ISO

Pyrethrins results in increased expression of HRK mRNA

NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561

G

hydroxysteroid (17-beta) dehydrogenase 3

affects expression

EXP

Pyrethrins affects the expression of HSD17B3 mRNA

NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

affects expression

EXP

Pyrethrins affects the expression of HSD3B1 mRNA

NCBI chr 2:188,858,574...188,864,694

G

heat shock transcription factor 2

affects expression

EXP

Pyrethrins affects the expression of HSF2 mRNA

NCBI chr20:37,366,301...37,393,922
Ensembl chr20:37,366,279...37,401,022

G

HtrA serine peptidase 4

decreases expression

EXP

Pyrethrins results in decreased expression of HTRA4 protein

NCBI chr16:73,704,255...73,717,722
Ensembl chr16:73,704,184...73,717,722

G

immunoglobulin superfamily, member 9

decreases expression

EXP

Pyrethrins results in decreased expression of IGSF9 protein

NCBI chr13:87,480,979...87,497,974
Ensembl chr13:87,481,279...87,497,974

G

interleukin 10

increases expression

ISO

Pyrethrins results in increased expression of IL10 mRNA

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

inhibin subunit beta A

increases expression

EXP

Pyrethrins results in increased expression of INHBA protein

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

insulin receptor

decreases expression

EXP

Pyrethrins results in decreased expression of INSR protein

NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803

G

insulin receptor-related receptor

decreases expression

EXP

Pyrethrins results in decreased expression of INSRR protein

NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:175,553,293...175,572,676

G

integrator complex subunit 14

decreases expression

EXP

Pyrethrins results in decreased expression of INTS14 protein

NCBI chr 8:74,370,687...74,398,153
Ensembl chr 8:74,371,015...74,396,209

G

IQ motif and Sec7 domain ArfGEF 3

decreases expression

EXP

Pyrethrins results in decreased expression of IQSEC3 protein

NCBI chr 4:156,283,040...156,379,396
Ensembl chr 4:156,283,043...156,379,396

G

inositol-trisphosphate 3-kinase C

decreases expression

EXP

Pyrethrins results in decreased expression of ITPKC protein

NCBI chr 1:91,628,606...91,650,182
Ensembl chr 1:91,628,608...91,653,350

G

intersectin 1

decreases expression

EXP

Pyrethrins results in decreased expression of ITSN1 protein

NCBI chr11:44,464,515...44,646,598
Ensembl chr11:44,513,186...44,646,598

G

kelch repeat and BTB domain containing 8

decreases expression

EXP

Pyrethrins results in decreased expression of KBTBD8 protein

NCBI chr 4:129,232,781...129,245,608
Ensembl chr 4:129,232,027...129,245,605

G

potassium voltage-gated channel subfamily A member 5

decreases expression

EXP

Pyrethrins results in decreased expression of KCNA5 protein

NCBI chr 4:161,040,853...161,044,311
Ensembl chr 4:160,996,950...161,044,408

G

potassium voltage-gated channel subfamily B member 2

decreases expression

EXP

Pyrethrins results in decreased expression of KCNB2 protein

NCBI chr 5:8,340,085...8,811,184
Ensembl chr 5:8,351,961...8,783,179

G

potassium voltage-gated channel subfamily H member 3

decreases expression

EXP

Pyrethrins results in decreased expression of KCNH3 protein

NCBI chr 7:132,244,492...132,262,725
Ensembl chr 7:132,244,880...132,262,721

G

potassium sodium-activated channel subfamily T member 1

decreases expression

EXP

Pyrethrins results in decreased expression of KCNT1 protein

NCBI chr 3:29,081,071...29,136,902
Ensembl chr 3:29,081,321...29,134,768

G

lysine demethylase 3A

decreases expression

EXP

Pyrethrins results in decreased expression of KDM3A protein

NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370

G

KiSS-1 metastasis-suppressor

increases expression
multiple interactions
affects expression

EXP
ISO

Pyrethrins results in increased expression of KISS1 protein
[[Environmental Pollutants results in increased abundance of Pyrethrins] which results in increased abundance of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid] which results in decreased methylation of KISS1 gene; [[Environmental Pollutants results in increased abundance of Pyrethrins] which results in increased abundance of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid] which results in increased secretion of KISS1 protein alternative form
Pyrethrins affects the expression of KISS1 protein

PMID:34896426 PMID:36053783 PMID:36657687

NCBI chr13:47,327,159...47,332,759
Ensembl chr13:47,327,004...47,332,906

G

KIT ligand

affects expression

EXP

Pyrethrins affects the expression of KITLG mRNA

NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793

G

L3MBTL histone methyl-lysine binding protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of L3MBTL2 protein

NCBI chr 7:115,066,427...115,087,625
Ensembl chr 7:115,066,486...115,087,598

G

lactase

decreases expression

EXP

Pyrethrins results in decreased expression of LCT protein

NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872

G

lymphoid enhancer binding factor 1

decreases expression

EXP

Pyrethrins results in decreased expression of LEF1 protein

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929

G

leptin receptor

decreases expression

EXP

Pyrethrins results in decreased expression of LEPR protein

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

luteinizing hormone subunit beta

decreases expression

EXP

Pyrethrins results in decreased expression of LHB protein

PMID:34896426 PMID:36053783

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

luteinizing hormone/choriogonadotropin receptor

decreases expression

EXP

Pyrethrins results in decreased expression of LHCGR mRNA; Pyrethrins results in decreased expression of LHR mRNA

PMID:34896426 PMID:36053783

NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061

G

lysophosphatidic acid receptor 3

decreases expression

EXP

Pyrethrins results in decreased expression of LPAR3 protein

NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197

G

LIM domain containing preferred translocation partner in lipoma

decreases expression

EXP

Pyrethrins results in decreased expression of LPP protein

NCBI chr11:89,292,060...89,933,973
Ensembl chr11:89,305,187...89,805,264

G

leucine rich repeat containing 8 VRAC subunit C

decreases expression

EXP

Pyrethrins results in decreased expression of LRRC8C protein

NCBI chr14:4,528,721...4,621,259
Ensembl chr14:4,531,823...4,620,049

G

latent transforming growth factor beta binding protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of LTBP2 protein

NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298

G

lymphotoxin beta receptor

increases expression

ISO

Pyrethrins results in increased expression of LTBR mRNA

NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

decreases expression

EXP

Pyrethrins results in decreased expression of MAGI2 protein

NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:15,278,518...16,762,199

G

MAM domain containing 4

increases expression

EXP

Pyrethrins results in increased expression of MAMDC4 protein

NCBI chr 3:28,780,523...28,789,139
Ensembl chr 3:28,780,523...28,789,139

G

mannosidase, alpha, class 1B, member 1

decreases expression

EXP

Pyrethrins results in decreased expression of MAN1B1 protein

NCBI chr 3:28,539,778...28,563,155
Ensembl chr 3:28,541,347...28,563,154

G

mannosidase, alpha, class 2C, member 1

decreases expression

EXP

Pyrethrins results in decreased expression of MAN2C1 protein

NCBI chr 8:66,434,480...66,445,649
Ensembl chr 8:66,434,421...66,445,648

G

mitogen-activated protein kinase kinase kinase 1

decreases expression

EXP

Pyrethrins results in decreased expression of MAP3K1 protein

NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897

G

microtubule affinity regulating kinase 1

decreases expression

EXP

Pyrethrins results in decreased expression of MARK1 protein

NCBI chr13:98,981,727...99,086,998
Ensembl chr13:98,983,020...99,086,701

G

microtubule associated serine/threonine kinase 1

decreases expression

EXP

Pyrethrins results in decreased expression of MAST1 protein

NCBI chr19:40,121,271...40,149,073
Ensembl chr19:40,112,831...40,149,073

G

MCL1 apoptosis regulator, BCL2 family member

increases expression

ISO

Pyrethrins results in increased expression of MCL1 mRNA

NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782

G

minichromosome maintenance 9 homologous recombination repair factor

decreases expression

EXP

Pyrethrins results in decreased expression of MCM9 protein

NCBI chr20:33,369,325...33,472,243
Ensembl chr20:33,387,611...33,472,243

G

minichromosome maintenance domain containing 2

decreases expression

EXP

Pyrethrins results in decreased expression of MCMDC2 protein

NCBI chr 5:14,071,609...14,120,435
Ensembl chr 5:14,080,968...14,120,351

G

MAM domain containing glycosylphosphatidylinositol anchor 2

affects expression

EXP

Pyrethrins affects the expression of MDGA2 mRNA

NCBI chr 6:90,482,687...91,346,784
Ensembl chr 6:90,498,119...91,344,413

G

mediator complex subunit 23

decreases expression

EXP

Pyrethrins results in decreased expression of MED23 protein

NCBI chr 1:22,309,613...22,377,745
Ensembl chr 1:22,309,613...22,356,754

G

microRNA 145

decreases expression

ISO

Pyrethrins results in decreased expression of MIR145A

NCBI chr18:57,369,983...57,370,070

G

microRNA 152

increases expression

ISO

Pyrethrins results in increased expression of MIR152

NCBI chr10:82,329,383...82,329,467
Ensembl chr10:82,329,383...82,329,467

G

microRNA 194-1

increases expression

ISO

Pyrethrins results in increased expression of MIR194

NCBI chr13:99,382,716...99,382,798
Ensembl chr13:99,382,716...99,382,798

G

microRNA 196a-2

increases expression

ISO

Pyrethrins results in increased expression of MIR196A-2

NCBI chr 7:135,988,876...135,988,985
Ensembl chr 7:135,988,876...135,988,985

G

microRNA 196b

increases expression

ISO

Pyrethrins results in increased expression of MIR196B

NCBI chr 4:82,661,101...82,661,185

G

microRNA 200c

decreases expression

ISO

Pyrethrins results in decreased expression of MIR200C

NCBI chr 4:159,209,965...159,210,033

G

malectin

decreases expression

EXP

Pyrethrins results in decreased expression of MLEC protein

NCBI chr12:41,458,234...41,468,710
Ensembl chr12:47,118,855...47,130,064

G

membrane metallo-endopeptidase-like 1

decreases expression

EXP

Pyrethrins results in decreased expression of MMEL1 protein

NCBI chr 5:170,713,602...170,744,058
Ensembl chr 5:170,713,627...170,744,058

G

mannose receptor, C type 2

decreases expression

EXP

Pyrethrins results in decreased expression of MRC2 protein

NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055

G

myosin regulatory light chain interacting protein

decreases expression

EXP

Pyrethrins results in decreased expression of MYLIP protein

NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,492,826...19,514,471

G

myosin IA

decreases expression

EXP

Pyrethrins results in decreased expression of MYO1A protein

NCBI chr 7:65,424,206...65,443,227
Ensembl chr 7:65,428,258...65,443,213

G

NBR1, autophagy cargo receptor

increases expression

EXP

Pyrethrins results in increased expression of NBR1 protein

NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,977,885...87,007,012

G

nuclear receptor coactivator 7

decreases expression

EXP

Pyrethrins results in decreased expression of NCOA7 mRNA

PMID:34896426 PMID:36053783

NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:28,675,426...28,835,886

G

NFE2 like bZIP transcription factor 2

affects expression

EXP

Pyrethrins affects the expression of NFE2L2 mRNA

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nuclear factor kappa B subunit 1

increases expression

ISO

Pyrethrins results in increased expression of NFKB1 mRNA

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

nemo like kinase

decreases expression

EXP

Pyrethrins results in decreased expression of NLK protein

NCBI chr10:63,965,432...64,089,006

G

nucleolar complex associated 4 homolog

decreases expression

EXP

Pyrethrins results in decreased expression of NOC4L protein

NCBI chr12:51,675,852...51,680,392
Ensembl chr12:51,675,838...51,680,390

G

nucleotide-binding oligomerization domain containing 1

decreases expression

ISO

Pyrethrins results in decreased expression of NOD1 mRNA

NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:85,391,151...85,441,674

G

N-acetylneuraminate pyruvate lyase

decreases expression

EXP

Pyrethrins results in decreased expression of NPL protein

NCBI chr13:68,205,602...68,247,940
Ensembl chr13:68,205,603...68,247,999

G

natriuretic peptide receptor 2

decreases expression

EXP

Pyrethrins results in decreased expression of NPR2 protein

NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:62,678,367...62,697,343

G

NAD(P)H quinone dehydrogenase 1

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of NQO1 mRNA
Pyrethrins affects the expression of NQO1 mRNA

PMID:34896426 PMID:36053783

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 0, group B, member 1

decreases expression

EXP

Pyrethrins results in decreased expression of NR0B1 mRNA

NCBI chr X:54,707,658...54,711,786
Ensembl chr X:54,707,639...54,712,083

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

ISO

Pyrethrins binds to and results in increased activity of NR1I2 protein

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

G

nuclear receptor subfamily 3, group C, member 2

decreases expression

EXP

Pyrethrins results in decreased expression of NR3C2 protein

NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078

G

neurexin 2

decreases expression

EXP

Pyrethrins results in decreased expression of NRXN2 protein

NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:213,155,673...213,271,526

G

2'-5'-oligoadenylate synthetase 3

increases expression

EXP

Pyrethrins results in increased expression of OAS3 protein

NCBI chr12:41,439,645...41,463,392
Ensembl chr12:41,439,643...41,464,420

G

outer dense fiber of sperm tails 2

decreases expression

EXP

Pyrethrins results in decreased expression of ODF2 protein

NCBI chr 3:33,557,738...33,605,076
Ensembl chr 3:33,558,832...33,605,076

G

olfactory receptor family 6 subfamily A member 2

decreases expression

EXP

Pyrethrins results in decreased expression of OR6A2 protein

NCBI chr 1:170,239,077...170,240,060
Ensembl chr 1:170,239,077...170,240,060

G

origin recognition complex, subunit 4

decreases expression

EXP

Pyrethrins results in decreased expression of ORC4 protein

NCBI chr 3:53,700,046...53,743,293
Ensembl chr 3:53,703,615...53,742,264

G

ovo like transcriptional repressor 1

affects expression

EXP

Pyrethrins affects the expression of OVOL1 mRNA

NCBI chr 1:212,284,601...212,296,106
Ensembl chr 1:212,284,605...212,296,106

G

phosphofurin acidic cluster sorting protein 1

affects expression

EXP

Pyrethrins affects the expression of PACS1 protein

NCBI chr 1:211,866,872...211,998,828
Ensembl chr 1:211,866,874...211,998,828

G

PAF1 homolog, Paf1/RNA polymerase II complex component

decreases expression

EXP

Pyrethrins results in decreased expression of PAF1 protein

NCBI chr 1:92,811,197...92,816,775
Ensembl chr 1:92,798,237...92,816,779

G

paralemmin

decreases expression

EXP

Pyrethrins results in decreased expression of PALM protein

NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:10,537,277...10,563,007

G

poly (ADP-ribose) polymerase 1

increases cleavage

ISO

Pyrethrins results in increased cleavage of PARP1 protein

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

proliferating cell nuclear antigen

decreases expression
increases expression

EXP

Pyrethrins results in decreased expression of PCNA mRNA
Pyrethrins results in increased expression of PCNA mRNA

PMID:34896426 PMID:36053783

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

PDS5 cohesin associated factor A

decreases expression

EXP

Pyrethrins results in decreased expression of PDS5A protein

NCBI chr14:42,905,734...43,004,740
Ensembl chr14:42,905,328...43,004,740

G

proline, glutamate and leucine rich protein 1

decreases expression

EXP

Pyrethrins results in decreased expression of PELP1 protein

NCBI chr10:55,593,444...55,610,478
Ensembl chr10:55,593,447...55,610,758

G

peroxisomal biogenesis factor 6

affects expression

EXP

Pyrethrins affects the expression of PEX6 protein

NCBI chr 9:21,755,747...21,767,939
Ensembl chr 9:21,755,751...21,767,908

G

post-GPI attachment to proteins inositol deacylase 1

decreases expression

EXP

Pyrethrins results in decreased expression of PGAP1 protein

NCBI chr 9:63,470,023...63,538,772
Ensembl chr 9:63,470,024...63,538,772

G

phosphatase and actin regulator 1

decreases expression

EXP

Pyrethrins results in decreased expression of PHACTR1 protein

NCBI chr17:21,769,006...22,246,227
Ensembl chr17:21,768,662...22,244,586

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

decreases expression

EXP

Pyrethrins results in decreased expression of PIK3CA protein

NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

decreases expression

EXP

Pyrethrins results in decreased expression of PIK3CB protein

NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331

G

phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha

decreases expression

EXP

Pyrethrins results in decreased expression of PIP5K1A protein

NCBI chr 2:185,317,319...185,361,859
Ensembl chr 2:185,317,319...185,360,476

G

phospholipase C, beta 2

decreases expression

EXP

Pyrethrins results in decreased expression of PLCB2 protein

NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221

G

phospholipase D1

decreases expression

EXP

Pyrethrins results in decreased expression of PLD1 protein

NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245

G

polo-like kinase 3

decreases expression

EXP

Pyrethrins results in decreased expression of PLK3 protein

NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:135,843,725...135,848,900

G

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

decreases expression

EXP

Pyrethrins results in decreased expression of PLOD3 protein

NCBI chr12:25,313,070...25,323,631
Ensembl chr12:25,313,072...25,323,631

G

pancreatic lipase

decreases expression

EXP

Pyrethrins results in decreased expression of PNLIP protein

NCBI chr 1:267,760,073...267,797,797
Ensembl chr 1:267,784,724...267,797,795

G

peroxisome proliferator activated receptor alpha

multiple interactions

ISO

Pyrethrins binds to and results in increased activity of PPARA protein

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

PTPRF interacting protein alpha 4

decreases expression

EXP

Pyrethrins results in decreased expression of PPFIA4 protein

NCBI chr13:48,305,844...48,354,329
Ensembl chr13:48,305,848...48,354,279

G

peptidylprolyl isomerase G

affects expression

EXP

Pyrethrins affects the expression of PPIG protein

NCBI chr 3:74,891,846...74,923,010
Ensembl chr 3:74,891,846...74,920,750

G

protein kinase cAMP-dependent type I regulatory subunit beta

affects expression

EXP

Pyrethrins affects the expression of PRKAR1B protein

NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766

G

prolactin

affects expression

EXP

Pyrethrins affects the expression of PRL protein

NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217

G

protamine 1

decreases expression

EXP

Pyrethrins results in decreased expression of PRM1 mRNA

NCBI chr10:5,378,740...5,379,235

G

protamine 2

affects expression

EXP

Pyrethrins affects the expression of PRM2 mRNA

NCBI chr10:4,876,285...4,877,026
Ensembl chr10:5,379,029...5,384,004

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 2

decreases expression

EXP

Pyrethrins results in decreased expression of PSMD2 protein

NCBI chr11:93,752,761...93,763,388
Ensembl chr11:93,752,763...93,763,388

G

phosphatidylserine synthase 2

decreases expression

EXP

Pyrethrins results in decreased expression of PTDSS2 protein

NCBI chr 1:205,671,024...205,695,556
Ensembl chr 1:205,671,041...205,695,553

G

prostaglandin-endoperoxide synthase 1

increases expression

EXP

Pyrethrins results in increased expression of PTGS1 protein

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990

G

protein tyrosine phosphatase, receptor type, S

decreases expression

EXP

Pyrethrins results in decreased expression of PTPRS protein

NCBI chr 9:1,332,558...1,394,161
Ensembl chr 9:1,332,559...1,394,093

G

PYD and CARD domain containing

decreases expression

ISO

Pyrethrins results in decreased expression of PYCARD mRNA

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419

G

Rap guanine nucleotide exchange factor 2

decreases expression

EXP

Pyrethrins results in decreased expression of RAPGEF2 protein

NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:166,505,868...166,726,698

G

RANBP2-type and C3HC4-type zinc finger containing 1

increases expression

EXP

Pyrethrins results in increased expression of RBCK1 protein

NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:161,249,390...161,266,032

G

RecQ like helicase

decreases expression

EXP

Pyrethrins results in decreased expression of RECQL protein

NCBI chr 4:177,039,351...177,063,968
Ensembl chr 4:177,035,128...177,063,838

G

RNA exonuclease 5

decreases expression

EXP

Pyrethrins results in decreased expression of REXO5 protein

NCBI chr 1:183,599,954...183,698,433
Ensembl chr 1:183,600,037...183,672,850

G

Rhox homeobox family member 5

affects expression

EXP

Pyrethrins affects the expression of RHOX5 mRNA

NCBI chr X:116,536,207...116,541,972

G

RIMS binding protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of RIMBP2 protein

NCBI chr12:33,383,646...33,582,259
Ensembl chr12:33,384,007...33,593,999

G

receptor-interacting serine-threonine kinase 2

increases expression

ISO

Pyrethrins results in increased expression of RIPK2 mRNA

NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663

G

RHO family interacting cell polarization regulator 2

decreases expression

EXP

Pyrethrins results in decreased expression of RIPOR2 protein

NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,751,771...40,975,337

G

ring finger protein 157

decreases expression

EXP

Pyrethrins results in decreased expression of RNF157 protein

NCBI chr10:102,070,842...102,138,738
Ensembl chr10:102,070,842...102,155,802

G

ring finger protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of RNF2 protein

NCBI chr13:66,103,943...66,136,038
Ensembl chr13:66,083,653...66,133,161

G

ring finger protein 8

decreases expression

EXP

Pyrethrins results in decreased expression of RNF8 protein

NCBI chr20:7,683,890...7,708,437

G

regulator of telomere elongation helicase 1

decreases expression

EXP

Pyrethrins results in decreased expression of RTEL1 protein

NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709

G

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

decreases expression

EXP

Pyrethrins results in decreased expression of SART1 protein

NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486

G

scavenger receptor class B, member 1

increases expression
affects expression

EXP

Pyrethrins results in increased expression of SCARB1 mRNA
Pyrethrins affects the expression of SCARB1 mRNA

PMID:34896426 PMID:36053783

NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980

G

secretogranin II

decreases expression

EXP

Pyrethrins results in decreased expression of SCG2 protein

NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:88,251,354...88,269,598

G

sodium voltage-gated channel beta subunit 4

decreases expression

EXP

Pyrethrins results in decreased expression of SCN4B protein

NCBI chr 8:54,343,873...54,359,046
Ensembl chr 8:54,334,548...54,359,047

G

sodium channel epithelial 1 subunit alpha

decreases expression

EXP

Pyrethrins results in decreased expression of SCNN1A protein

NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405

G

SEC16 homolog B, endoplasmic reticulum export factor

decreases expression

EXP

Pyrethrins results in decreased expression of SEC16B protein

NCBI chr13:72,206,778...72,260,733
Ensembl chr13:72,206,772...72,260,729

G

semaphorin 6C

decreases expression

EXP

Pyrethrins results in decreased expression of SEMA6C protein

NCBI chr 2:185,422,636...185,436,237
Ensembl chr 2:185,422,639...185,448,689

G

SID1 transmembrane family, member 2

decreases expression

EXP

Pyrethrins results in decreased expression of SIDT2 protein

NCBI chr 8:55,129,091...55,146,446
Ensembl chr 8:55,129,091...55,145,408

G

sirtuin 1

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of SIRT1 mRNA
Pyrethrins affects the expression of SIRT1 mRNA

PMID:34896426 PMID:36053783

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000

G

solute carrier family 12 member 1

affects expression

EXP

Pyrethrins affects the expression of SLC12A1 protein

NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340

G

solute carrier family 26 member 3

decreases expression

EXP

Pyrethrins results in decreased expression of SLC26A3 protein

NCBI chr 6:53,751,415...53,792,300
Ensembl chr 6:53,751,415...53,792,294

G

solute carrier family 38, member 5

decreases expression

EXP

Pyrethrins results in decreased expression of SLC38A5 protein

NCBI chr X:16,885,701...16,894,470
Ensembl chr X:16,885,701...16,894,470

G

solute carrier family 44 member 2

decreases expression

EXP

Pyrethrins results in decreased expression of SLC44A2 protein

NCBI chr 8:28,147,023...28,181,496
Ensembl chr 8:28,147,030...28,181,495

G

solute carrier family 4 member 4

decreases expression

EXP

Pyrethrins results in decreased expression of SLC4A4 protein

NCBI chr14:19,125,394...19,577,379
Ensembl chr14:19,129,264...19,577,435

G

solute carrier family 52 member 2

decreases expression

EXP

Pyrethrins results in decreased expression of SLC52A2 protein

NCBI chr 7:110,126,632...110,146,647
Ensembl chr 7:110,143,220...110,158,809

G

solute carrier family 9 member A4

decreases expression

EXP

Pyrethrins results in decreased expression of SLC9A4 protein

NCBI chr 9:50,320,948...50,375,336
Ensembl chr 9:50,320,586...50,375,335

G

schlafen family member 9

decreases expression

EXP

Pyrethrins results in decreased expression of SLFN13 protein

NCBI chr10:68,406,641...68,420,062
Ensembl chr10:68,406,642...68,421,134

G

SNF2 related chromatin remodeling ATPase with DExD box 1

decreases expression

EXP

Pyrethrins results in decreased expression of SMARCAD1 protein

NCBI chr 4:95,639,722...95,709,055
Ensembl chr 4:95,641,295...95,702,414

G

structural maintenance of chromosomes 3

decreases expression

EXP

Pyrethrins results in decreased expression of SMC3 protein

NCBI chr 1:262,606,731...262,649,832
Ensembl chr 1:262,607,080...262,649,825

G

sushi, nidogen and EGF-like domains 1

decreases expression

EXP

Pyrethrins results in decreased expression of SNED1 protein

NCBI chr 9:93,774,087...93,834,003
Ensembl chr 9:101,221,530...101,281,401

G

sine oculis binding protein homolog

decreases expression

EXP

Pyrethrins results in decreased expression of SOBP protein

NCBI chr20:48,064,445...48,243,607
Ensembl chr20:48,064,445...48,243,607

G

SRY-box transcription factor 9

decreases expression

EXP

Pyrethrins results in decreased expression of SOX9 mRNA

PMID:34896426 PMID:36053783

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

sperm associated antigen 1

decreases expression

EXP

Pyrethrins results in decreased expression of SPAG1 protein

NCBI chr 7:69,246,301...69,306,483
Ensembl chr 7:69,246,582...69,306,482

G

sterol regulatory element binding transcription factor 2

affects expression

EXP

Pyrethrins affects the expression of SREBF2 protein

NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943

G

structure specific recognition protein 1

decreases expression

EXP

Pyrethrins results in decreased expression of SSRP1 protein

NCBI chr 3:90,531,024...90,541,132
Ensembl chr 3:90,530,829...90,541,129

G

stabilin 2

decreases expression

EXP

Pyrethrins results in decreased expression of STAB2 protein

NCBI chr 7:23,136,938...23,342,633
Ensembl chr 7:23,136,941...23,320,562

G

steroidogenic acute regulatory protein

increases expression
affects expression

EXP

Pyrethrins results in increased expression of STAR mRNA
Pyrethrins affects the expression of STAR mRNA

PMID:34896426 PMID:36053783

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

syntaxin 12

decreases expression

EXP

Pyrethrins results in decreased expression of STX12 protein

NCBI chr 5:150,347,554...150,376,426
Ensembl chr 5:150,334,836...150,376,346

G

synergin, gamma

decreases expression

EXP

Pyrethrins results in decreased expression of SYNRG protein

NCBI chr10:69,346,154...69,428,714
Ensembl chr10:69,322,114...69,428,714

G

TGF-beta activated kinase 1/MAP3K7 binding protein 2

decreases expression

EXP

Pyrethrins results in decreased expression of TAB2 protein

NCBI chr 1:4,195,400...4,245,485
Ensembl chr 1:4,195,400...4,245,485

G

TBC1 domain family, member 2

decreases expression

EXP

Pyrethrins results in decreased expression of TBC1D2 protein

NCBI chr 5:65,679,670...65,727,978
Ensembl chr 5:65,679,680...65,726,996

G

T-box transcription factor 5

decreases expression

EXP

Pyrethrins results in decreased expression of TBX5 protein

NCBI chr12:42,342,926...42,399,723
Ensembl chr12:42,348,485...42,395,359

G

tet methylcytosine dioxygenase 1

affects expression

EXP

Pyrethrins affects the expression of TET1 mRNA

NCBI chr20:25,766,806...25,839,598
Ensembl chr20:25,760,057...25,832,730

G

testis expressed 14, intercellular bridge forming factor

decreases expression

EXP

Pyrethrins results in decreased expression of TEX14 protein

NCBI chr10:72,729,017...72,859,697
Ensembl chr10:72,728,985...72,853,064

G

transforming growth factor, beta 1

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of TGFB1 protein
Pyrethrins affects the expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

transforming growth factor, beta 2

decreases expression

EXP

Pyrethrins results in decreased expression of TGFB2 mRNA

NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856

G

transglutaminase 1

decreases expression

EXP

Pyrethrins results in decreased expression of TGM1 protein

NCBI chr15:33,160,985...33,175,632
Ensembl chr15:33,160,987...33,174,463

G

trans-golgi network protein 2

increases expression

EXP

Pyrethrins results in increased expression of TGOLN2 protein

NCBI chr 4:106,221,503...106,229,360
Ensembl chr 4:106,221,509...106,229,262

G

tigger transposable element derived 5

decreases expression

EXP

Pyrethrins results in decreased expression of TIGD5 protein

NCBI chr 7:109,477,438...109,479,957
Ensembl chr 7:109,477,338...109,480,508

G

TNF receptor superfamily member 10b

increases expression

ISO

Pyrethrins results in increased expression of TNFRSF10A mRNA

NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082

G

TNF receptor superfamily member 11B

increases expression

ISO

Pyrethrins results in increased expression of TNFRSF11B mRNA

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075

G

TNF receptor superfamily member 1A

increases expression

ISO

Pyrethrins results in increased expression of TNFRSF1A mRNA

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF receptor superfamily member 21

increases expression

ISO

Pyrethrins results in increased expression of TNFRSF21 mRNA

NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:25,376,400...25,451,323

G

TNF receptor superfamily member 25

decreases expression

ISO

Pyrethrins results in decreased expression of TNFRSF25 mRNA

NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:167,904,786...167,909,052

G

TNF superfamily member 10

decreases expression

ISO

Pyrethrins results in decreased expression of TNFSF10 mRNA

NCBI chr 2:112,136,550...112,155,903

G

transition protein 2

affects expression

EXP

Pyrethrins affects the expression of TNP2 mRNA

NCBI chr10:4,879,812...4,880,540
Ensembl chr10:5,383,885...5,387,467

G

tumor protein p73

decreases expression

ISO

Pyrethrins results in decreased expression of TP73 mRNA

NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552

G

TNFRSF1A-associated via death domain

decreases expression

ISO

Pyrethrins results in decreased expression of TRADD mRNA

NCBI chr19:50,046,057...50,048,158
Ensembl chr19:50,046,061...50,052,550

G

Tnf receptor-associated factor 2

decreases expression

ISO

Pyrethrins results in decreased expression of TRAF2 mRNA

NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691

G

tRNA aspartic acid methyltransferase 1

affects expression
decreases expression

EXP

Pyrethrins affects the expression of TRDMT1 mRNA
Pyrethrins results in decreased expression of TRDMT1 mRNA

PMID:34896426 PMID:36053783

NCBI chr17:81,510,740...81,554,036
Ensembl chr17:81,521,200...81,577,639

G

tripartite motif-containing 35

decreases expression

EXP

Pyrethrins results in decreased expression of TRIM35 protein

NCBI chr15:44,669,222...44,685,766
Ensembl chr15:44,656,322...44,685,765

G

transient receptor potential cation channel, subfamily A, member 1

decreases expression

EXP

Pyrethrins results in decreased expression of TRPA1 protein

NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325

G

transient receptor potential cation channel, subfamily C, member 1

decreases expression

EXP

Pyrethrins results in decreased expression of TRPC1 protein

NCBI chr 8:105,142,931...105,193,842
Ensembl chr 8:105,142,931...105,193,826

G

transient receptor potential cation channel, subfamily C, member 3

decreases expression

EXP

Pyrethrins results in decreased expression of TRPC3 protein

NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:121,409,436...121,475,823

G

transient receptor potential cation channel, subfamily C, member 4

decreases expression

EXP

Pyrethrins results in decreased expression of TRPC4 protein

NCBI chr 2:140,457,841...140,629,556
Ensembl chr 2:140,458,296...140,626,969

G

transient receptor potential cation channel, subfamily M, member 2

increases expression

EXP

Pyrethrins results in increased expression of TRPM2 mRNA

NCBI chr20:10,703,190...10,752,795
Ensembl chr20:10,704,482...10,752,802

G

thyroid stimulating hormone subunit beta

increases expression

EXP

Pyrethrins results in increased expression of TSHB protein

NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984

G

translocator protein

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of TSPO mRNA
Pyrethrins affects the expression of TSPO mRNA

PMID:34896426 PMID:36053783

NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:116,600,210...116,610,460

G

unc-13 homolog B

decreases expression

EXP

Pyrethrins results in decreased expression of UNC13B protein

NCBI chr 5:62,084,809...62,299,884
Ensembl chr 5:62,084,819...62,299,884

G

unc-5 netrin receptor D

decreases expression

EXP

Pyrethrins results in decreased expression of UNC5D protein

NCBI chr16:69,563,099...70,109,862
Ensembl chr16:69,563,212...70,104,078

G

ubiquitin specific peptidase 4

decreases expression

EXP

Pyrethrins results in decreased expression of USP4 protein

NCBI chr 8:117,912,576...117,957,934
Ensembl chr 8:117,914,614...117,957,949

G

vav guanine nucleotide exchange factor 1

decreases expression

EXP

Pyrethrins results in decreased expression of VAV1 protein

NCBI chr 9:2,248,856...2,295,905
Ensembl chr 9:2,248,914...2,296,922

G

ventricular zone expressed PH domain-containing 1

decreases expression

EXP

Pyrethrins results in decreased expression of VEPH1 protein

NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:152,601,680...152,847,318

G

vimentin

decreases expression

EXP

Pyrethrins results in decreased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746

G

WASH complex subunit 2C

decreases expression

EXP

Pyrethrins results in decreased expression of WASHC2 protein

NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:150,912,395...150,998,301

G

WD repeat domain 26

decreases expression

EXP

Pyrethrins results in decreased expression of WDR26 protein

NCBI chr13:95,462,017...95,503,826
Ensembl chr13:95,462,020...95,503,738

G

WD repeat domain 81

decreases expression

EXP

Pyrethrins results in decreased expression of WDR81 protein

NCBI chr10:60,780,268...60,793,671
Ensembl chr10:60,780,268...60,793,592

G

WT1 transcription factor

increases expression
decreases expression

EXP

Pyrethrins results in increased expression of WT1 mRNA
Pyrethrins results in decreased expression of WT1 mRNA

PMID:34896426 PMID:36053783

NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:112,021,641...112,068,444

G

X-linked inhibitor of apoptosis

increases expression

ISO

Pyrethrins results in increased expression of XIAP mRNA

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978

G

Y box binding protein 2

decreases expression
affects expression

EXP

Pyrethrins results in decreased expression of YBX2 mRNA
Pyrethrins affects the expression of YBX2 mRNA

PMID:34896426 PMID:36053783

NCBI chr10:55,158,420...55,164,077
Ensembl chr10:55,158,420...55,164,077

G

zinc finger protein 148

decreases expression

EXP

Pyrethrins results in decreased expression of ZNF148 protein

NCBI chr11:80,780,865...80,890,877
Ensembl chr11:80,786,087...80,890,877

G

zinc finger protein 335

decreases expression

EXP

Pyrethrins results in decreased expression of ZNF335 protein

NCBI chr 3:174,046,789...174,073,076
Ensembl chr 3:174,046,243...174,067,534

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	20862
chemical entity	20860
atom	20860
nonmetal atom	20766
carbon atom	20710
organic molecular entity	20710
olefinic compound	17360
(R,R)-chrysanthemal	350
(+)-trans-chrysanthemic acid +	350
Path 2
Term	Annotations
CHEBI ontology	20862
subatomic particle	20860
composite particle	20860
hadron	20860
baryon	20860
nucleon	20860
atomic nucleus	20860
atom	20860
main group element atom	20781
p-block element atom	20781
carbon group element atom	20715
carbon atom	20710
organic molecular entity	20710
heteroorganic entity	20219
organochalcogen compound	19904
organooxygen compound	19806
carbon oxoacid	19155
carboxylic acid	19152
carboacyl group	18085
univalent carboacyl group	18085
formyl group	9407
aldehyde	9407
aliphatic aldehyde	2440
(R,R)-chrysanthemal	350
(+)-trans-chrysanthemic acid +	350

paths to the root