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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor
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Accession:CHEBI:143828 term browser browse the term
Definition:Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of sterol 14alpha-demethylase (EC 1.14.14.154).
Synonyms:related_synonym: CYP51 inhibitor;   CYP51 inhibitors;   EC 1.14.14.154 inhibitor;   EC 1.14.14.154 inhibitors;   ERG11 inhibitor;   ERG11 inhibitors;   cytochrome P450 51 inhibitor;   cytochrome P450 51 inhibitors;   lanosterol 14-demethylase inhibitor;   lanosterol 14-demethylase inhibitors;   lanosterol 14alpha-demethylase inhibitor;   lanosterol 14alpha-demethylase inhibitors;   obtusufoliol 14-demethylase inhibitor;   obtusufoliol 14-demethylase inhibitors;   oxidoreductase (14-methyl cleaving) inhibitors;   sterol 14-demethylase inhibitor;   sterol 14-demethylase inhibitors;   sterol 14alpha-demethylase (EC 1.14.14.154) inhibitors;   sterol 14alpha-demethylase inhibitor;   sterol 14alpha-demethylase inhibitors;   sterol,[reduced NADPH--hemoprotein reductase]:oxygen inhibitor;   sterol,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving) inhibitor


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Path 1
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  CHEBI ontology 19899
    role 19870
      biological role 19868
        biochemical role 19579
          enzyme inhibitor 18775
            EC 1.* (oxidoreductase) inhibitor 17563
              EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 16001
                EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor 1256
                  EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor 0
                    ravuconazole 0
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