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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ganoderol B
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Accession:CHEBI:142261 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species.
Synonyms:exact_synonym: (3beta,24E)-lanosta-7,9(11),24-triene-3,26-diol
 related_synonym: Formula=C30H48O2;   InChI=1S/C30H48O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25-26,31-32H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=AOXXVRDKZLRGTJ-AZIDVCJLSA-N;   SMILES=C1([C@]2([C@](CC[C@@H]1O)(C=3C(=CC2)[C@]4([C@@](CC3)(C)[C@](CC4)([C@@H](CC/C=C(/CO)\\C)C)[H])C)C)[H])(C)C;   ganodermadiol
 xref: CAS:104700-96-1;   FooDB:FDB013983;   HMDB:HMDB0035314;   KNApSAcK:C00023868
 xref_mesh: MESH:C521787
 xref: PMID:11908995;   PMID:12628419;   PMID:17313101;   PMID:17499997;   PMID:21596546;   PMID:23790868;   PMID:28875673;   PMID:28912878;   PMID:29748985


show annotations for term's descendants           Sort by:
ganoderol B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO ganoderol B binds to and results in decreased activity of AR protein; ganoderol B inhibits the reaction [Dihydrotestosterone binds to AR protein] CTD PMID:17499997 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO ganoderol B results in decreased expression of KLK3 mRNA CTD PMID:17499997 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity EXP ganoderol B results in decreased activity of SRD5A1 protein CTD PMID:17499997 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        antimicrobial agent 18250
          antiviral agent 11343
            ganoderol B 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic polycyclic compound 17291
                                  steroid 14716
                                    hydroxy steroid 14466
                                      3-hydroxy steroid 12807
                                        sterol 466
                                          3beta-sterol 460
                                            ganoderol B 3
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