Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine
go back to main search page
Accession:CHEBI:142183 term browser browse the term
Definition:A 1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine that has S configuration. A selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt.
Synonyms:exact_synonym: (2S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine
 related_synonym: (1S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine;   (S)-2-(6-chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine;   (S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine;   (S)-6-chloro-5-fluoro-alpha-methyl-1H-indole-1-ethanamine;   Formula=C11H12ClFN2;   InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1;   InChIKey=XJJZQXUGLLXTHO-ZETCQYMHSA-N;   ORG 35030;   Ro-60-0175;   Ro60-0175;   SMILES=C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N
 xref: LINCS:LSM-1601;   PMID:10219979;   PMID:10498829;   PMID:10814735;   PMID:10903970;   PMID:11105935;   PMID:11399662;   PMID:12604698;   PMID:14666118;   PMID:17473916;   PMID:17653111;   PMID:22342986;   PMID:23201361;   PMID:23535834;   PMID:28583411;   PMID:9225301;   PMID:9694950;   Patent:EP655440;   Reaxys:7795121;   Wikipedia:Ro60-0175



show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19869
      biological role 19867
        pharmacological role 19102
          agonist 18635
            5-hydroxytryptamine 2B receptor agonist 12
              (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            organic molecule 19724
                              organic cyclic compound 19516
                                organic heterocyclic compound 18896
                                  organic heteropolycyclic compound 18323
                                    organic heterobicyclic compound 17262
                                      benzopyrrole 9752
                                        indoles 9441
                                          1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine 0
                                            (2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine 0
paths to the root