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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-methoxycatechol
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Accession:CHEBI:141700 term browser browse the term
Definition:A member of the class of catechols that is catechol in which a hydrogen that is ortho to one of the hydroxy groups has been replaced by a methoxy group. It displays agonistic activity against G protein-coupled receptor 35 (GPR35).
Synonyms:exact_synonym: 3-methoxybenzene-1,2-diol
 related_synonym: 1,2-dihydroxy-3-methoxybenzene;   1-O-methylpyrogallol;   2,3-dihydroxyanisole;   3-methoxy-o-hydroquinone;   3-methoxypyrocatechol;   6-methoxycatechol;   Formula=C7H8O3;   InChI=1S/C7H8O3/c1-10-6-4-2-3-5(8)7(6)9/h2-4,8-9H,1H3;   InChIKey=LPYUENQFPVNPHY-UHFFFAOYSA-N;   SMILES=C=1(C=CC=C(C1O)OC)O;   pyrogallol 1-methyl ether;   pyrogallol 1-monomethyl ether
 xref: CAS:934-00-9;   HMDB:HMDB0125538
 xref_mesh: MESH:C066344
 xref: PMID:15231803;   PMID:20280766;   PMID:2121686;   PMID:23402862;   PMID:24276120;   PMID:2731816;   PMID:28394572;   PMID:29950589;   PMID:8416747;   Reaxys:1909165


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3-methoxycatechol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of 3-methoxycatechol CTD PMID:11160877 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO 3-methoxycatechol results in increased expression of NFE2L2 mRNA CTD PMID:26862668 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        pharmacological role 19080
          agonist 18607
            G-protein-coupled receptor agonist 83
              3-methoxycatechol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic aromatic compound 19360
                                  phenols 18655
                                    phenolic donor 599
                                      pyrogallol 184
                                        3-methoxycatechol 2
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