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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Arabidopsis thaliana metabolite
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Accession:CHEBI:140602 term browser browse the term
Definition:Any plant metabolite that is produced by Arabidopsis thaliana.
Synonyms:related_synonym: Arabidopsis thaliana metabolites
 xref: Wikipedia:Arabidopsis_thaliana



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dGTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 decreases abundance ISO SAMHD1 protein results in decreased abundance of deoxyguanosine triphosphate CTD PMID:26342080 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386
JBrowse link
fraxetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO fraxetin inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]
fraxetin results in decreased phosphorylation of AKT1 protein
CTD PMID:34553399 PMID:37867445 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO fraxetin results in decreased expression of BAX protein
Fraxetin increases expression of BAX protein in colorectum
fraxetin results in increased expression of BAX mRNA; fraxetin results in increased expression of BAX protein
CTD
RGD
PMID:15996779 PMID:37867445 PMID:32504672 RGD:125097526 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Fraxetin decreases expression of BCL2 protein in colorectum
fraxetin results in decreased expression of BCL2 mRNA; fraxetin results in decreased expression of BCL2 protein
CTD
RGD
PMID:37867445 PMID:32504672 RGD:125097526 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 decreases activity
increases cleavage
ISO fraxetin results in decreased activity of CASP3 protein
fraxetin results in increased cleavage of CASP3 protein
CTD PMID:15996779 PMID:37867445 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 decreases activity ISO fraxetin results in decreased activity of CASP9 protein CTD PMID:15996779 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO fraxetin inhibits the reaction [Rotenone results in increased expression of and results in increased activity of CAT protein] CTD PMID:15904944 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Fraxetin decreases expression of CCNA2 protein in colorectum RGD PMID:32504672 RGD:125097526 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Fraxetin decreases expression of CCNE1 protein in colorectum RGD PMID:32504672 RGD:125097526 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Fraxetin decreases expression of CDK2 protein in colorectum RGD PMID:32504672 RGD:125097526 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO fraxetin affects the localization of CYCS protein CTD PMID:15996779 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Il6 interleukin 6 multiple interactions ISO fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA] CTD PMID:30496664 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO Fraxetin decreases phosphorylation of JAK2 protein in colorectum RGD PMID:32504672 RGD:125097526 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases phosphorylation ISO fraxetin results in decreased phosphorylation of MAPK8 protein CTD PMID:37867445 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO fraxetin results in decreased expression of MKI67 protein CTD PMID:37867445 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO fraxetin results in increased cleavage of PARP1 protein CTD PMID:37867445 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO Fraxetin decreases expression of SKP2 mRNA and protein in colorectum RGD PMID:32504672 RGD:125097526 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO fraxetin inhibits the reaction [Rotenone results in increased expression of and results in increased activity of SOD2 protein] CTD PMID:15904944 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO Fraxetin decreases phosphorylation of STAT3 protein in colorectum RGD PMID:32504672 RGD:125097526 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA] CTD PMID:30496664 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        biochemical role 19556
          metabolite 19544
            eukaryotic metabolite 19368
              plant metabolite 17985
                Arabidopsis thaliana metabolite 20
                  (-)-retigeranin B 0
                  (4-methoxyindol-3-ylmethyl)isothiocyanate 0
                  1-(2-oxindole-3-acetyl)-beta-D-glucose 0
                  1-isothiocyanato-6-(methylsulfanyl)hexane 0
                  2,5-dihydroxybenzoic acid 2-O-beta-D-glucoside 0
                  2-O-(beta-D-glucosyl)glycerol 0
                  2-hydroxy-3-butenyldesulfoglucosinolate 0
                  2-hydroxylinoleic acid 0
                  2-trans-4'-dihydroabscisic acid 0
                  26-hydroxybrassinolide 0
                  3-(isothiocyanatomethyl)-1-methoxyindole 0
                  3-butenyldesulfoglucosinolate 0
                  3-hydroxypropyl isothiocyanate 0
                  4-hydroxy-indole-3-carbonyl nitrile 0
                  4-hydroxybutylnitrile 0
                  4-methoxy-3-indolylmethylamine 0
                  4-methoxy-3-indolylmethylamine(1+) 0
                  5-(methylthio)pentyldesulfoglucosinolate 0
                  6-(methylthio)hexanonitrile oxide 0
                  6-(methylthio)hexyldesulfoglucosinolate 0
                  6-hydroxynicotinic acid 0
                  6-methoxycamalexin 0
                  6-sinapoylglucoraphenin 0
                  7-(alpha-D-glucosyl)dihydrozeatin 0
                  7-(methylthio)heptanonitrile oxide 0
                  7-(methylthio)heptyldesulfoglucosinolate 0
                  7-hydroxy-2-oxindole-3-acetic acid beta-D-glucoside 0
                  8-(methylthio)octylisothiocyanate 0
                  N-[(6-hydroxyindol-3-yl)acetyl]phenylalanine 0
                  S-[9-(methylthio)nonylhydroximoyl]-L-cysteine 0
                  all-cis-hexadeca-7,10,13-trienoate phytyl ester 0
                  caprate phytyl ester 0
                  coniferaldehyde beta-D-glucoside 0
                  dGTP 1
                  dUTP + 0
                  decan-3-ol 0
                  desulfoglucoiberin 0
                  desulfogluconasturtiin 0
                  desulfosinigrin 0
                  dihydrozeatin-9-N-glucoside-O-glucoside 0
                  fraxetin + 19
                  glucohesperin 0
                  indole-3-carbonyl nitrile 0
                  laurate phytyl ester 0
                  levoglucosan + 0
                  myristate phytyl ester 0
                  palmitate phytyl ester 0
                  raphanusamic acid 0
                  sideretin (reduced form) + 0
                  thiamine(1+) monophosphate + 0
                  thiamine(1+) triphosphate 0
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