CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | HT-2 toxin |
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Accession: | CHEBI:138861
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browse the term
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Definition: | A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin. |
Synonyms: | exact_synonym: | 15-(acetyloxy)-3alpha,4beta-dihydroxy-12,13-epoxytrichothec-9-en-8alpha-yl 3-methylbutanoate |
| related_synonym: | Formula=C22H32O8; HT-2; InChI=1S/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22-/m0/s1; InChIKey=PNKLMTPXERFKEN-MLXHEQMXSA-N; SMILES=[H][C@@]12O[C@]3([H])C=C(C)[C@H](C[C@]3(COC(C)=O)[C@@](C)([C@H](O)[C@H]1O)[C@]21CO1)OC(=O)CC(C)C; mycotoxin HT-2 |
| xref: | CAS:26934-87-2; KEGG:C19952; KNApSAcK:C00012651 |
| xref_mesh: | MESH:C012351 |
| xref: | MetaCyc:CPD-18504; PMID:11352533; PMID:27929394; PMID:28093223; PMID:28425967; PMID:28780481; PMID:28937260; PMID:29710820; PMID:29909314; PMID:30831213; PMID:30870695; PMID:30903560; PMID:31072003; PMID:31232057; PMID:31409003; PMID:31731600; PMID:32062580; PMID:32217092; PMID:32275576; PMID:32298583; PMID:32466723; PMID:32604961; PMID:32871192; PMID:32910237; PMID:32990831; PMID:6696412 |
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Casp3 |
caspase 3 |
increases activity |
ISO |
HT-2 toxin results in increased activity of CASP3 protein |
CTD |
PMID:19428930 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of CYP11A mRNA |
CTD |
PMID:22982764 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of CYP17A1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
HT-2 toxin results in increased expression of CYP1A1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Ephx1 |
epoxide hydrolase 1 |
increases expression |
ISO |
HT-2 toxin results in increased expression of EPHX1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Gip |
gastric inhibitory polypeptide |
multiple interactions |
ISO |
HT-2 toxin results in increased expression of and results in increased secretion of GIP protein |
CTD |
PMID:28666375 |
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NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503
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Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of HMGCR mRNA |
CTD |
PMID:22982764 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
increases expression |
ISO |
HT-2 toxin results in increased expression of HSD17B1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
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A2m |
alpha-2-macroglobulin |
multiple interactions decreases expression |
ISO |
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein] T-2 Toxin results in decreased expression of A2M mRNA; T-2 Toxin results in decreased expression of A2M protein |
CTD |
PMID:21144892 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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Aars1 |
alanyl-tRNA synthetase 1 |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of AARS1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ABCB1A mRNA |
CTD |
PMID:26141394 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abraxas2 |
abraxas 2, BRISC complex subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of ABRAXAS2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:187,647,078...187,672,660
Ensembl chr 1:187,647,067...187,672,655
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Acan |
aggrecan |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ACAN mRNA; T-2 Toxin results in decreased expression of ACAN protein |
CTD |
PMID:16624732 PMID:18196609 PMID:22800716 PMID:31863870 |
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NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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Acat2 |
acetyl-CoA acetyltransferase 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of ACAT2 protein |
CTD |
PMID:26141394 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acly |
ATP citrate lyase |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ACLY mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Aco2 |
aconitase 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of ACO2 protein |
CTD |
PMID:26141394 |
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NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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Actb |
actin, beta |
affects expression |
EXP |
T-2 Toxin affects the expression of ACTB protein |
CTD |
PMID:26141394 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Actr1a |
actin related protein 1A |
increases expression |
ISO |
T-2 Toxin results in increased expression of ACTR1A mRNA; T-2 Toxin results in increased expression of ACTR1A protein |
CTD |
PMID:34581912 |
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NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495
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Adam9 |
ADAM metallopeptidase domain 9 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ADAM9 mRNA |
CTD |
PMID:34581912 |
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NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
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Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:22800716 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ADAMTS5 mRNA |
CTD |
PMID:18196609 PMID:22800716 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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Adk |
adenosine kinase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ADK protein |
CTD |
PMID:34581912 |
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NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
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Adprh |
ADP-ribosylarginine hydrolase |
affects expression |
EXP |
T-2 Toxin affects the expression of ADPRH protein |
CTD |
PMID:26141394 |
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NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931
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Afg1l |
AFG1 like ATPase |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L] |
CTD |
PMID:36863559 |
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NCBI chr20:45,798,344...45,967,997
Ensembl chr20:45,798,349...45,967,906
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Afg2a |
AFG2 AAA ATPase homolog A |
increases expression |
EXP |
T-2 Toxin results in increased expression of AFG2A mRNA |
CTD |
PMID:26141394 |
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NCBI chr 2:120,306,417...120,497,707
Ensembl chr 2:120,306,412...120,497,705
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Ahcy |
adenosylhomocysteinase |
increases expression |
ISO |
T-2 Toxin results in increased expression of AHCY protein |
CTD |
PMID:34581912 |
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NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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Ahr |
aryl hydrocarbon receptor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of AHR protein |
CTD |
PMID:31470059 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Aimp2 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AIMP2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769
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Ak2 |
adenylate kinase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AK2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632
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Akap3 |
A-kinase anchoring protein 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AKAP3 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 4:159,688,049...159,714,067
Ensembl chr 4:159,699,289...159,713,903
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Akap4 |
A-kinase anchoring protein 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AKAP4 mRNA |
CTD |
PMID:34581912 |
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NCBI chr X:15,435,391...15,445,684
Ensembl chr X:15,435,410...15,445,684
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Akirin2 |
akirin 2 |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of AKIRIN2 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
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Akna |
AT-hook transcription factor |
decreases expression multiple interactions affects localization |
EXP |
T-2 Toxin results in decreased expression of AKNA mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]; T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter] T-2 Toxin affects the localization of AKNA protein |
CTD |
PMID:26141394 PMID:29079362 |
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NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
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Akt1 |
AKT serine/threonine kinase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of AKT1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Akt1s1 |
AKT1 substrate 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of AKT1S1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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Alas1 |
5'-aminolevulinate synthase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ALAS1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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Alas2 |
5'-aminolevulinate synthase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ALAS2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519
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Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
affects expression increases expression |
EXP |
T-2 Toxin affects the expression of ALDH1A1 protein T-2 Toxin results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldoc |
aldolase, fructose-bisphosphate C |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ALDOC mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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Alpl |
alkaline phosphatase, biomineralization associated |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ALPL protein |
CTD |
PMID:35289972 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Angptl7 |
angiopoietin like 7 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ANGPTL7 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324
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Anln |
anillin, actin binding protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ANLN mRNA |
CTD |
PMID:34581912 |
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NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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Anp32b |
acidic nuclear phosphoprotein 32 family member B |
affects expression |
EXP |
T-2 Toxin affects the expression of ANP32B protein |
CTD |
PMID:26141394 |
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NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
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Anxa1 |
annexin A1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ANXA1 protein |
CTD |
PMID:34581912 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Anxa5 |
annexin A5 |
affects expression |
EXP |
T-2 Toxin affects the expression of ANXA5 protein |
CTD |
PMID:26141394 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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Apoe |
apolipoprotein E |
increases expression |
EXP |
T-2 Toxin results in increased expression of APOE mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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App |
amyloid beta precursor protein |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of APP mRNA |
CTD |
PMID:26141394 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Aprt |
adenine phosphoribosyl transferase |
affects expression |
EXP |
T-2 Toxin affects the expression of APRT protein |
CTD |
PMID:26141394 |
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NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431
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Ar |
androgen receptor |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to AR] |
CTD |
PMID:36863559 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Areg |
amphiregulin |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA] |
CTD |
PMID:30951242 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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Arhgap18 |
Rho GTPase activating protein 18 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ARHGAP18 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
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Arl5c |
ARF like GTPase 5C |
increases expression |
EXP |
T-2 Toxin results in increased expression of ARL5C mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:82,985,213...82,993,425
Ensembl chr10:82,985,216...82,992,002
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Arrb2 |
arrestin, beta 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ARRB2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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Arsa |
arylsulfatase A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ARSA mRNA |
CTD |
PMID:26141394 |
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NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783
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Asap3 |
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ASAP3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073
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Asb14 |
ankyrin repeat and SOCS box-containing 14 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ASB14 mRNA |
CTD |
PMID:26141394 |
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NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135
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Asb5 |
ankyrin repeat and SOCS box-containing 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ASB5 mRNA |
CTD |
PMID:26141394 |
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NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109
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Asb6 |
ankyrin repeat and SOCS box-containing 6 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ASB6 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 3:14,110,628...14,115,274
Ensembl chr 3:14,110,628...14,115,242
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Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ASNS mRNA |
CTD |
PMID:31863870 PMID:34581912 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Ass1 |
argininosuccinate synthase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ASS1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
ISO |
salubrinal promotes the reaction [T-2 Toxin results in increased expression of ATF4 protein] |
CTD |
PMID:34673134 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atg12 |
autophagy related 12 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ATG12 protein |
CTD |
PMID:26138683 |
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NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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Atg14 |
autophagy related 14 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ATG14 mRNA |
CTD |
PMID:26138683 |
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NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
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G |
Atg3 |
autophagy related 3 |
increases expression multiple interactions |
EXP ISO |
T-2 Toxin results in increased expression of ATG3 protein ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein] T-2 Toxin results in increased expression of ATG3 mRNA; T-2 Toxin results in increased expression of ATG3 protein |
CTD |
PMID:29870751 PMID:32240701 |
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NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
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G |
Atg5 |
autophagy related 5 |
affects expression increases expression multiple interactions |
EXP ISO |
T-2 Toxin affects the expression of ATG5 protein T-2 Toxin results in increased expression of ATG5 protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of ATG5 protein] |
CTD |
PMID:29413859 PMID:35289972 PMID:36402210 |
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atic |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ATIC protein |
CTD |
PMID:34581912 |
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NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
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G |
Atm |
ATM serine/threonine kinase |
increases phosphorylation decreases expression |
ISO |
T-2 Toxin results in increased phosphorylation of ATM protein T-2 Toxin results in decreased expression of ATM mRNA |
CTD |
PMID:20150440 PMID:34581912 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atp11a |
ATPase phospholipid transporting 11A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ATP11A mRNA |
CTD |
PMID:26141394 |
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NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ATP1A1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP5F1A protein |
CTD |
PMID:26141394 |
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NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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G |
Atp5f1b |
ATP synthase F1 subunit beta |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP5F1B protein |
CTD |
PMID:26141394 |
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NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP5PD protein |
CTD |
PMID:26141394 |
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NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP6V1A protein |
CTD |
PMID:26141394 |
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NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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G |
Atp6v1b2 |
ATPase H+ transporting V1 subunit B2 |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP6V1B2 protein |
CTD |
PMID:26141394 |
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NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
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G |
Atp8b2 |
ATPase phospholipid transporting 8B2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ATP8B2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883
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G |
Aup1 |
AUP1, lipid droplet regulating VLDL assembly factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of AUP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346
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G |
Axl |
Axl receptor tyrosine kinase |
increases expression |
ISO |
T-2 Toxin results in increased expression of AXL mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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G |
B2m |
beta-2 microglobulin |
increases expression |
ISO |
T-2 Toxin results in increased expression of B2M protein |
CTD |
PMID:33508416 |
|
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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G |
Bag5 |
BAG cochaperone 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of BAG5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of BAK1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
affects localization multiple interactions increases expression affects expression decreases expression |
ISO EXP |
T-2 Toxin affects the localization of BAX protein Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA] T-2 Toxin results in increased expression of BAX mRNA; T-2 Toxin results in increased expression of BAX protein T-2 Toxin affects the expression of BAX protein T-2 Toxin results in decreased expression of BAX protein |
CTD |
PMID:16307838 PMID:19524637 PMID:19541794 PMID:21296132 PMID:26138683 PMID:26314264 PMID:28697680 PMID:29413859 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35289972 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of BBC3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcat1 |
branched chain amino acid transaminase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BCAT1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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G |
Bccip |
BRCA2 and CDKN1A interacting protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of BCCIP mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression increases activity |
EXP ISO |
T-2 Toxin results in increased expression of BCL2 mRNA; T-2 Toxin results in increased expression of BCL2 protein T-2 Toxin results in decreased expression of BCL2 mRNA T-2 Toxin results in decreased expression of BCL2 mRNA; T-2 Toxin results in decreased expression of BCL2 protein T-2 Toxin results in increased activity of BCL2 protein |
CTD |
PMID:19524637 PMID:21296132 PMID:28697680 PMID:29870751 PMID:33508416 PMID:34581912 PMID:35289972 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression affects expression |
ISO EXP |
T-2 Toxin results in decreased expression of BCL2L1 mRNA; T-2 Toxin results in decreased expression of BCL2L1 protein T-2 Toxin affects the expression of BCL2L1 protein |
CTD |
PMID:29413859 PMID:29432840 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
increases expression multiple interactions affects expression |
EXP ISO |
T-2 Toxin results in increased expression of BECN1 mRNA 3-methyladenine inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Sirolimus promotes the reaction [T-2 Toxin results in increased expression of BECN1 mRNA] T-2 Toxin results in increased expression of BECN1 protein T-2 Toxin affects the expression of BECN1 protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of BECN1 protein] |
CTD |
PMID:30629952 PMID:35289972 PMID:36402210 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BGLAP protein |
CTD |
PMID:35289972 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bid |
BH3 interacting domain death agonist |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BID protein |
CTD |
PMID:29432840 |
|
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bnip3l |
BCL2 interacting protein 3 like |
increases expression |
EXP |
T-2 Toxin results in increased expression of BNIP3L mRNA |
CTD |
PMID:29870751 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
Bop1 |
BOP1 ribosomal biogenesis factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of BOP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931
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G |
Bpnt1 |
3'(2'), 5'-bisphosphate nucleotidase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of BPNT1 protein |
CTD |
PMID:26141394 |
|
NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
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G |
Brip1 |
BRCA1 interacting DNA helicase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BRIP1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
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G |
Bud23 |
BUD23, rRNA methyltransferase and ribosome maturation factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of BUD23 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:21,629,551...21,640,758
Ensembl chr12:21,629,536...21,640,751
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G |
C5 |
complement C5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of C5 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
Calm1 |
calmodulin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CALM1 protein |
CTD |
PMID:26141394 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Capns1 |
calpain, small subunit 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CAPNS1 protein |
CTD |
PMID:26141394 |
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NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795
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G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of CARS1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
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G |
Casp12 |
caspase 12 |
multiple interactions increases expression |
ISO EXP |
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA] salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 protein] T-2 Toxin results in increased expression of CASP12 mRNA; T-2 Toxin results in increased expression of CASP12 protein |
CTD |
PMID:34673134 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression affects expression |
EXP ISO |
3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Sirolimus inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP3 protein T-2 Toxin results in increased expression of CASP3 mRNA T-2 Toxin results in increased expression of CASP3 mRNA; T-2 Toxin results in increased expression of CASP3 protein; T-2 Toxin results in increased expression of CASP3 protein modified form Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]; T-2 Toxin results in increased expression of and results in increased activity of CASP3 protein; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein] T-2 Toxin affects the expression of CASP3 protein |
CTD |
PMID:19428930 PMID:19524637 PMID:19541794 PMID:21295106 PMID:21296132 PMID:26138683 PMID:28697680 PMID:29413859 PMID:29432840 PMID:29567467 PMID:29870751 PMID:30629952 PMID:33508416 PMID:35289972 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
increases activity |
ISO |
T-2 Toxin results in increased activity of CASP7 protein |
CTD |
PMID:19524637 |
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
increases expression increases activity multiple interactions |
EXP ISO |
T-2 Toxin results in increased expression of CASP8 mRNA T-2 Toxin results in increased activity of CASP8 protein Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein] |
CTD |
PMID:26141394 PMID:29432840 PMID:29567467 PMID:29870751 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity multiple interactions increases expression |
ISO EXP |
T-2 Toxin results in increased activity of CASP9 protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP9 protein T-2 Toxin results in increased expression of CASP9 mRNA Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein] |
CTD |
PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:33508416 PMID:35289972 More...
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
increases activity decreases expression multiple interactions decreases activity increases expression |
ISO EXP |
T-2 Toxin results in increased activity of CAT protein T-2 Toxin results in decreased expression of CAT mRNA T-2 Toxin affects the expression of and affects the activity of CAT protein T-2 Toxin results in decreased activity of CAT protein T-2 Toxin results in increased expression of CAT mRNA |
CTD |
PMID:19526462 PMID:21112371 PMID:23929680 PMID:27842451 PMID:29432840 PMID:29870751 PMID:30091165 PMID:33508416 PMID:34581912 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cbr1 |
carbonyl reductase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CBR1 protein |
CTD |
PMID:26141394 |
|
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Ccdc137 |
coiled-coil domain containing 137 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CCDC137 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:105,730,776...105,737,158
Ensembl chr10:105,730,739...105,737,158
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G |
Ccdc34 |
coiled-coil domain containing 34 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CCDC34 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146
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G |
Ccn3 |
cellular communication network factor 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCN3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
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G |
Ccnb1ip1 |
cyclin B1 interacting protein 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CCNB1IP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475
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G |
Ccnb2 |
cyclin B2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCNB2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO EXP |
T-2 Toxin results in decreased expression of CCND1 mRNA T-2 Toxin results in decreased expression of CCND1 mRNA; T-2 Toxin results in decreased expression of CCND1 protein |
CTD |
PMID:22454431 PMID:29567467 PMID:35289972 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccng1 |
cyclin G1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCNG1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Ccng2 |
cyclin G2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCNG2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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G |
Cct2 |
chaperonin containing TCP1 subunit 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCT2 protein |
CTD |
PMID:34581912 |
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NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
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G |
Cd24 |
CD24 molecule |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CD24 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
T-2 Toxin results in increased expression of CD274 protein |
CTD |
PMID:36115646 |
|
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
T-2 Toxin results in increased expression of CD40 mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd44 |
CD44 molecule |
multiple interactions decreases expression |
ISO |
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein] T-2 Toxin results in decreased expression of CD44 mRNA; T-2 Toxin results in decreased expression of CD44 protein |
CTD |
PMID:18196609 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd55 |
CD55 molecule (Cromer blood group) |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CD55 mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
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G |
Cdc42bpa |
CDC42 binding protein kinase alpha |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CDC42BPA mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732
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G |
Cdca5 |
cell division cycle associated 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDCA5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
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G |
Cdca7 |
cell division cycle associated 7 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDCA7 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdca8 |
cell division cycle associated 8 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDCA8 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CDK4 mRNA; T-2 Toxin results in decreased expression of CDK4 protein |
CTD |
PMID:29567467 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdk5 |
cyclin-dependent kinase 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CDK5 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
|
|
G |
Cdk5rap1 |
CDK5 regulatory subunit associated protein 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDK5RAP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677
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|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO EXP |
T-2 Toxin results in increased expression of CDKN1A mRNA T-2 Toxin results in increased expression of CDKN1A mRNA; T-2 Toxin results in increased expression of CDKN1A protein |
CTD |
PMID:22454431 PMID:29567467 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
|
|
G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDKN2A mRNA; T-2 Toxin results in increased expression of CDKN2A protein |
CTD |
PMID:29567467 |
|
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CDKN3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cenpe |
centromere protein E |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CENPE mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
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G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CENPF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Cenpj |
centromere protein J |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CPAP mRNA |
CTD |
PMID:34581912 |
|
NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791
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G |
Cep135 |
centrosomal protein 135 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CEP135 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:31,530,538...31,595,812
Ensembl chr14:31,531,482...31,595,772
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G |
Cfap96 |
cilia and flagella associated protein 96 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CFAP96 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:46,291,075...46,315,616
Ensembl chr16:46,291,311...46,315,625
|
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G |
Cfl1 |
cofilin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CFL1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions |
ISO |
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA] |
CTD |
PMID:25962641 PMID:30951242 |
|
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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|
G |
Cgrrf1 |
cell growth regulator with ring finger domain 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CGRRF1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
|
|
G |
Chek2 |
checkpoint kinase 2 |
multiple interactions increases activity |
ISO |
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein] |
CTD |
PMID:20150440 |
|
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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|
G |
Chpf |
chondroitin polymerizing factor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CHPF mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CHRNA4 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CHRNB2 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
|
|
G |
Ciita |
class II, major histocompatibility complex, transactivator |
increases expression |
ISO |
T-2 Toxin results in increased expression of CIITA mRNA |
CTD |
PMID:36775139 |
|
NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
|
|
G |
Cit |
citron rho-interacting serine/threonine kinase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CIT mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
|
|
G |
Ckb |
creatine kinase B |
affects expression |
EXP |
T-2 Toxin affects the expression of CKB protein |
CTD |
PMID:26141394 |
|
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
|
|
G |
Ckmt2 |
creatine kinase, mitochondrial 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CKMT2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430
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|
G |
Cldn3 |
claudin 3 |
multiple interactions decreases expression |
ISO |
illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN3 mRNA] |
CTD |
PMID:27153755 |
|
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
|
|
G |
Cldn4 |
claudin 4 |
multiple interactions decreases expression |
ISO |
illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN4 mRNA] |
CTD |
PMID:27153755 |
|
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
|
|
G |
Clic1 |
chloride intracellular channel 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CLIC1 protein |
CTD |
PMID:26141394 |
|
NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
|
|
G |
Cln8 |
CLN8, transmembrane ER and ERGIC protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of CLN8 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
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|
G |
Clu |
clusterin |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of CLU mRNA T-2 Toxin results in increased expression of CLU mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
|
|
G |
Cnpy2 |
canopy FGF signaling regulator 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of CNPY2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519
|
|
G |
Cntf |
ciliary neurotrophic factor |
increases expression |
EXP |
T-2 Toxin results in increased expression of CNTF mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
|
|
G |
Coa5 |
cytochrome C oxidase assembly factor 5 |
multiple interactions increases expression |
EXP |
GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5] |
CTD |
PMID:36863559 |
|
NCBI chr 9:39,651,459...39,664,870
|
|
G |
Col10a1 |
collagen type X alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL10A1 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
|
|
G |
Col11a1 |
collagen type XI alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL11A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
|
|
G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL15A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL1A1 mRNA |
CTD |
PMID:22800716 PMID:35289972 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
|
|
G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions decreases expression |
ISO |
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of COL1A2 protein] |
CTD |
PMID:36402210 |
|
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL2A1 mRNA |
CTD |
PMID:22800716 PMID:34673134 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G |
Col9a1 |
collagen type IX alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL9A1 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213
|
|
G |
Colgalt2 |
collagen beta(1-O)galactosyltransferase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COLGALT2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:64,523,641...64,628,295
Ensembl chr13:64,523,658...64,627,549
|
|
G |
Cope |
COPI coat complex subunit epsilon |
affects expression |
EXP |
T-2 Toxin affects the expression of COPE protein |
CTD |
PMID:26141394 |
|
NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907
|
|
G |
Copz1 |
COPI coat complex subunit zeta 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of COPZ1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:134,409,523...134,435,661
Ensembl chr 7:134,409,799...134,435,662
|
|
G |
Coq5 |
coenzyme Q5, methyltransferase |
increases expression |
ISO |
T-2 Toxin results in increased expression of COQ5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848
|
|
G |
Coro1c |
coronin 1C |
increases expression |
ISO |
T-2 Toxin results in increased expression of CORO1C mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179
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G |
Coro2b |
coronin 2B |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CORO2B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
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|
G |
Cox15 |
cytochrome c oxidase assembly homolog COX15 |
increases expression |
ISO |
T-2 Toxin results in increased expression of COX15 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
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|
G |
Cox19 |
cytochrome c oxidase assembly factor COX19 |
increases expression |
ISO |
T-2 Toxin results in increased expression of COX19 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014
|
|
G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
multiple interactions decreases expression |
ISO |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of COX4I1 protein] |
CTD |
PMID:27363784 |
|
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Cox6c |
cytochrome c oxidase subunit 6C |
affects expression |
EXP |
T-2 Toxin affects the expression of COX6C protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
|
|
G |
Cox6c-ps1 |
cytochrome c oxidase subunit VIc, pseudogene |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of COX6C-PS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr19:52,192,612...52,193,470
Ensembl chr19:52,192,612...52,193,470
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
affects localization multiple interactions |
EXP |
T-2 Toxin affects the localization of CREB1 protein modified form T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter] |
CTD |
PMID:29079362 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
|
|
G |
Creb3l1 |
cAMP responsive element binding protein 3-like 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CREB3L1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
|
|
G |
Creb5 |
cAMP responsive element binding protein 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CREB5 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
|
|
G |
Crem |
cAMP responsive element modulator |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CREM mRNA |
CTD |
PMID:26141394 |
|
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
|
|
G |
Crtc3 |
CREB regulated transcription coactivator 3 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CRTC3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500
|
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G |
Cryab |
crystallin, alpha B |
increases expression |
ISO |
T-2 Toxin results in increased expression of CRYAB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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G |
Cs |
citrate synthase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CS protein |
CTD |
PMID:34581912 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
|
|
G |
Csf1 |
colony stimulating factor 1 |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of CSF1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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|
G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CSRNP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
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G |
Cst3 |
cystatin C |
increases expression |
ISO |
T-2 Toxin results in increased expression of CST3 protein |
CTD |
PMID:33508416 |
|
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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G |
Cth |
cystathionine gamma-lyase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CTH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
|
|
G |
Ctnnb1 |
catenin beta 1 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of CTNNB1 mRNA; T-2 Toxin results in decreased expression of CTNNB1 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of CTNNB1 protein] |
CTD |
PMID:35289972 PMID:36402210 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
|
|
G |
Ctrl |
chymotrypsin-like |
affects expression |
EXP |
T-2 Toxin affects the expression of CTRB1 protein |
CTD |
PMID:26141394 |
|
NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
|
|
G |
Ctsa |
cathepsin A |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CTSA mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
|
|
G |
Cwc27 |
CWC27 spliceosome associated cyclophilin |
increases expression |
ISO |
T-2 Toxin results in increased expression of CWC27 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:35,764,674...35,975,908
Ensembl chr 2:35,764,686...35,975,872
|
|
G |
Cyb5r1 |
cytochrome b5 reductase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CYB5R1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458
|
|
G |
Cyc1 |
cytochrome c-1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CYC1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
|
|
G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
T-2 Toxin affects the localization of CYCS protein |
CTD |
PMID:19541794 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
|
|
G |
Cyfip1 |
cytoplasmic FMR1 interacting protein 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CYFIP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA T-2 Toxin results in decreased expression of CYP11A1 mRNA T-2 Toxin results in increased expression of CYP11A1 mRNA |
CTD |
PMID:25962641 PMID:26141394 PMID:34581912 |
|
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein |
CTD |
PMID:25962641 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
|
|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of CYP19A1 mRNA 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA] |
CTD |
PMID:22982764 PMID:30951242 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]; T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter] T-2 Toxin results in increased expression of CYP1A1 mRNA; T-2 Toxin results in increased expression of CYP1A1 protein |
CTD |
PMID:21453744 PMID:22982764 PMID:31470059 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cytl1 |
cytokine like 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CYTL1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886
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G |
Dars2 |
aspartyl-tRNA synthetase 2 (mitochondrial) |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of DARS2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934
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G |
Dcps |
decapping enzyme, scavenger |
increases expression |
ISO |
T-2 Toxin results in increased expression of DCPS mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389
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G |
Dcx |
doublecortin |
increases expression |
ISO |
T-2 Toxin results in increased expression of DCX mRNA |
CTD |
PMID:26314264 |
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NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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G |
Dcxr |
dicarbonyl and L-xylulose reductase |
increases expression |
ISO |
T-2 Toxin results in increased expression of DCXR mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:106,006,404...106,008,293
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G |
Ddb2 |
damage specific DNA binding protein 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DDB2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
EXP ISO |
T-2 Toxin results in increased expression of DDIT3 mRNA; T-2 Toxin results in increased expression of DDIT3 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein] salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein] |
CTD |
PMID:26141394 PMID:29454614 PMID:34673134 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DDIT4 mRNA |
CTD |
PMID:34581912 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddx52 |
DExD-box helicase 52 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DDX52 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266
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G |
Ddx55 |
DEAD-box helicase 55 |
multiple interactions increases expression |
EXP |
GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55] |
CTD |
PMID:36863559 |
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NCBI chr12:32,034,462...32,050,218
Ensembl chr12:32,034,462...32,050,219
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G |
Ddx56 |
DEAD-box helicase 56 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DDX56 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333
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G |
Dffa |
DNA fragmentation factor subunit alpha |
increases expression |
ISO |
T-2 Toxin results in increased expression of DFFA mRNA |
CTD |
PMID:34581912 |
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NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633
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G |
Dgcr8 |
DGCR8 microprocessor complex subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of DGCR8 mRNA |
CTD |
PMID:34581912 |
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NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DHCR24 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
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NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of DIABLO protein |
CTD |
PMID:34581912 |
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NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
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G |
Disc1 |
DISC1 scaffold protein |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to DISC1] |
CTD |
PMID:36863559 |
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NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
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G |
Dnajc10 |
DnaJ heat shock protein family (Hsp40) member C10 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DNAJC10 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
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G |
Dnajc4 |
DnaJ heat shock protein family (Hsp40) member C4 |
affects expression |
EXP |
T-2 Toxin affects the expression of DNAJC4 protein |
CTD |
PMID:26141394 |
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NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
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G |
Dnase1l1 |
deoxyribonuclease 1-like 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DNASE1L1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr X:152,056,942...152,065,518
Ensembl chr X:152,056,942...152,065,518
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G |
Dnase2 |
deoxyribonuclease 2, lysosomal |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DNASE2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376
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G |
Dnm1l |
dynamin 1-like |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of DNM1L mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L] |
CTD |
PMID:36863559 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of DNMT1 mRNA; T-2 Toxin results in increased expression of DNMT1 protein |
CTD |
PMID:31279042 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3a |
DNA methyltransferase 3 alpha |
increases expression |
EXP |
T-2 Toxin results in increased expression of DNMT3A mRNA; T-2 Toxin results in increased expression of DNMT3A protein |
CTD |
PMID:31279042 |
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NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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G |
Dok3 |
docking protein 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of DOK3 mRNA |
CTD |
PMID:26141394 |
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NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188
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G |
Dph1 |
diphthamide biosynthesis 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of DPH1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
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G |
Dpy19l1 |
dpy-19 like C-mannosyltransferase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DPY19L1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751
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G |
Dstn |
destrin, actin depolymerizing factor |
affects expression |
EXP |
T-2 Toxin affects the expression of DSTN protein |
CTD |
PMID:26141394 |
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NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
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G |
Dusp1 |
dual specificity phosphatase 1 |
decreases expression increases expression |
EXP ISO |
T-2 Toxin results in decreased expression of DUSP1 mRNA T-2 Toxin results in increased expression of DUSP1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr10:16,680,478...16,683,275
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G |
Dynll1 |
dynein light chain LC8-type 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DYNLL1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741
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G |
Ecm2 |
extracellular matrix protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ECM2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
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G |
Eef1d |
eukaryotic translation elongation factor 1 delta |
affects expression |
EXP |
T-2 Toxin affects the expression of EEF1D protein |
CTD |
PMID:26141394 |
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NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
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G |
Eef1g |
eukaryotic translation elongation factor 1 gamma |
affects expression |
EXP |
T-2 Toxin affects the expression of EEF1G protein |
CTD |
PMID:26141394 |
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NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of EEF2 protein |
CTD |
PMID:26141394 |
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NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
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G |
Eeig1 |
estrogen-induced osteoclastogenesis regulator 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EEIG1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643
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G |
Efhd1 |
EF-hand domain family, member D1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EFHD1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
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G |
Egf |
epidermal growth factor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EGF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF2AK2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
decreases expression increases phosphorylation |
ISO |
T-2 Toxin results in decreased expression of EIF2AK3 mRNA T-2 Toxin results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:31863870 PMID:34673134 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
EXP ISO |
T-2 Toxin results in increased phosphorylation of EIF2S1 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] salubrinal promotes the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:29454614 PMID:34673134 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif3d |
eukaryotic translation initiation factor 3, subunit D |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF3D mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206
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G |
Eif3g |
eukaryotic translation initiation factor 3, subunit G |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF3G mRNA |
CTD |
PMID:26141394 |
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NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
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G |
Eif3i |
eukaryotic translation initiation factor 3, subunit I |
affects expression |
EXP |
T-2 Toxin affects the expression of EIF3I protein |
CTD |
PMID:26141394 |
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NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
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G |
Eif3j |
eukaryotic translation initiation factor 3, subunit J |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF3J mRNA |
CTD |
PMID:26141394 |
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NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953
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G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF4A2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
affects expression |
EXP |
T-2 Toxin affects the expression of EIF5A protein |
CTD |
PMID:26141394 |
|
NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Eif6 |
eukaryotic translation initiation factor 6 |
affects expression |
EXP |
T-2 Toxin affects the expression of EIF6 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
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G |
Eloc |
elongin C |
affects expression |
EXP |
T-2 Toxin affects the expression of ELOC protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890 Ensembl chr20:2,661,724...2,677,890
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G |
Emg1 |
EMG1 N1-specific pseudouridine methyltransferase |
increases expression |
ISO |
T-2 Toxin results in increased expression of EMG1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540
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G |
Eno1 |
enolase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of ENO1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
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G |
Eomes |
eomesodermin |
increases expression |
ISO |
T-2 Toxin results in increased expression of EOMES mRNA |
CTD |
PMID:26314264 |
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NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions increases expression |
ISO |
BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA]; BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein] T-2 Toxin results in increased expression of EPAS1 mRNA; T-2 Toxin results in increased expression of EPAS1 protein |
CTD |
PMID:22800716 PMID:34581912 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Epb41l2 |
erythrocyte membrane protein band 4.1-like 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EPB41L2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721
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G |
Epb42 |
erythrocyte membrane protein band 4.2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of EPB42 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EPRS1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Epyc |
epiphycan |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EPYC mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135
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G |
Ereg |
epiregulin |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA] |
CTD |
PMID:30951242 |
|
NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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G |
Ergic2 |
ERGIC and golgi 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ERGIC2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:181,090,808...181,123,074
Ensembl chr 4:181,090,808...181,123,060
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G |
Ermp1 |
endoplasmic reticulum metallopeptidase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ERMP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of ERN1 protein ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein] |
CTD |
PMID:31170431 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of ERN2 protein ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein] |
CTD |
PMID:31170431 |
|
NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
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G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ERO1A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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G |
Erp29 |
endoplasmic reticulum protein 29 |
affects expression |
EXP |
T-2 Toxin affects the expression of ERP29 protein |
CTD |
PMID:26141394 |
|
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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G |
Esrra |
estrogen related receptor, alpha |
affects expression |
EXP |
T-2 Toxin affects the expression of ESRRA mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
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G |
Exosc2 |
exosome component 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of EXOSC2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
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G |
Ezr |
ezrin |
affects expression |
EXP |
T-2 Toxin affects the expression of EZR protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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G |
Fam162a |
family with sequence similarity 162, member A |
increases expression |
ISO |
T-2 Toxin results in increased expression of FAM162A mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239
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G |
Fam216a |
family with sequence similarity 216, member A |
increases expression |
ISO |
T-2 Toxin results in increased expression of FAM216A mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:34,198,526...34,207,673
Ensembl chr12:34,198,526...34,207,665
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G |
Fanci |
FA complementation group I |
increases expression |
EXP |
T-2 Toxin results in increased expression of FANCI mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
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G |
Fbxo2 |
F-box protein 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of FBXO2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
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G |
Fbxo22 |
F-box protein 22 |
increases expression |
ISO |
T-2 Toxin results in increased expression of FBXO22 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148
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G |
Fbxo31 |
F-box protein 31 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31] |
CTD |
PMID:36863559 |
|
NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010
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G |
Fbxw4 |
F-box and WD repeat domain containing 4 |
increases expression |
EXP |
T-2 Toxin results in increased expression of FBXW4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:244,426,892...244,514,188
Ensembl chr 1:244,426,896...244,514,163
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G |
Fcgr2b |
Fc gamma receptor 2B |
increases expression |
EXP |
T-2 Toxin results in increased expression of FCGR2B mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
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G |
Fech |
ferrochelatase |
increases expression |
ISO |
T-2 Toxin results in increased expression of FECH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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G |
Fgf4 |
fibroblast growth factor 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of FGF4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
EXP |
PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA] |
CTD |
PMID:36863559 |
|
NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fkbp4 |
FKBP prolyl isomerase 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of FKBP4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
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G |
Fmod |
fibromodulin |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of FMOD mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of FOSL2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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G |
Fscn1 |
fascin actin-bundling protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of FSCN1 protein |
CTD |
PMID:26141394 |
|
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
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G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression multiple interactions |
EXP ISO |
T-2 Toxin results in decreased expression of FSHB protein 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Estradiol]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Progesterone] |
CTD |
PMID:26569305 PMID:30951242 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fubp1 |
far upstream element binding protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of FUBP1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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G |
Fuca1 |
alpha-L-fucosidase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of FUCA1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
affects expression decreases expression |
EXP |
T-2 Toxin affects the expression of G6PD protein T-2 Toxin results in decreased expression of G6PD mRNA |
CTD |
PMID:26141394 |
|
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of GABBR1 mRNA T-2 Toxin results in decreased expression of GABBR1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
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G |
Gabpa |
GA binding protein transcription factor subunit alpha |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of GABPA mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L]; T-2 Toxin promotes the reaction [GABPA protein binds to AR]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55]; T-2 Toxin promotes the reaction [GABPA protein binds to DISC1]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L]; T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7]; T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C]; T-2 Toxin promotes the reaction [GABPA protein binds to PARG]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]; T-2 Toxin promotes the reaction [GABPA protein binds to UQCRFS1]; T-2 Toxin promotes the reaction [GABPA protein binds to YARS2]; T-2 Toxin results in increased expression of and results in increased localization of GABPA protein |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
EXP |
T-2 Toxin results in increased expression of GADD45G mRNA |
CTD |
PMID:26141394 |
|
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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G |
Gadd45gip1 |
GADD45G interacting protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GADD45GIP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr19:23,320,662...23,323,211
Ensembl chr19:23,320,159...23,323,236
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G |
Gal |
galanin and GMAP prepropeptide |
increases expression |
ISO |
T-2 Toxin results in increased expression of GAL mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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G |
Galnt1 |
polypeptide N-acetylgalactosaminyltransferase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GALNT1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
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G |
Gan |
gigaxonin |
increases expression |
ISO |
T-2 Toxin results in increased expression of GAN mRNA |
CTD |
PMID:34581912 |
|
NCBI chr19:45,207,783...45,265,066
Ensembl chr19:45,207,184...45,254,107
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G |
Ganab |
glucosidase II alpha subunit |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GANAB protein |
CTD |
PMID:34581912 |
|
NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
affects expression decreases expression |
EXP |
T-2 Toxin affects the expression of GAPDH protein T-2 Toxin results in decreased expression of GAPDH mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gas6 |
growth arrest specific 6 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GAS6 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gask1b |
golgi associated kinase 1B |
increases expression |
ISO |
T-2 Toxin results in increased expression of GASK1B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
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G |
Gatb |
glutamyl-tRNA amidotransferase subunit B |
increases expression |
ISO |
T-2 Toxin results in increased expression of GATB mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:170,930,547...171,017,133
Ensembl chr 2:170,930,542...171,016,695
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G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GATM mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
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G |
Gbe1 |
1,4-alpha-glucan branching enzyme 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GBE mRNA |
CTD |
PMID:34581912 |
|
NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
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G |
Gbp5 |
guanylate binding protein 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GBP5 mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of GCLC mRNA T-2 Toxin results in increased expression of GCLC mRNA |
CTD |
PMID:20854872 PMID:33508416 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of GCLM mRNA T-2 Toxin results in increased expression of GCLM mRNA |
CTD |
PMID:20854872 PMID:33508416 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GDF15 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gdf5 |
growth differentiation factor 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GDF5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612
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G |
Gdpd5 |
glycerophosphodiester phosphodiesterase domain containing 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GDPD5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
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G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GFPT1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
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G |
Gh1 |
growth hormone 1 |
multiple interactions decreases expression |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; T-2 Toxin results in decreased expression of and results in decreased secretion of GH1 protein |
CTD |
PMID:26141394 PMID:29079362 |
|
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
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G |
Ghitm |
growth hormone inducible transmembrane protein |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GHITM mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
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G |
Ghrh |
growth hormone releasing hormone |
increases expression |
EXP |
T-2 Toxin results in increased expression of GHRH mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
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G |
Gip |
gastric inhibitory polypeptide |
multiple interactions increases expression |
ISO |
T-2 Toxin results in increased expression of and results in increased secretion of GIP protein T-2 Toxin results in increased expression of GIP protein |
CTD |
PMID:28666375 PMID:29689362 |
|
NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503
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G |
Glmp |
glycosylated lysosomal membrane protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GLMP mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960
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G |
Gnrh1 |
gonadotropin releasing hormone 1 |
decreases expression increases expression |
EXP |
T-2 Toxin results in decreased expression of GNRH1 mRNA T-2 Toxin results in increased expression of GNRH1 mRNA |
CTD |
PMID:26569305 PMID:26847343 |
|
NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581 Ensembl chr15:41,972,905...41,973,581
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G |
Gnrhr |
gonadotropin releasing hormone receptor |
increases expression |
EXP |
T-2 Toxin results in increased expression of GNRHR mRNA |
CTD |
PMID:26847343 |
|
NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
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G |
Gp6 |
glycoprotein VI |
increases expression |
ISO |
T-2 Toxin results in increased expression of GP6 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
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G |
Gpatch4 |
G patch domain containing 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GPATCH4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684
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G |
Gpc4 |
glypican 4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPC4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284
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G |
Gpr21 |
G protein-coupled receptor 21 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPR21 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930
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G |
Gpr52 |
G protein-coupled receptor 52 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPR52 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:72,800,265...72,804,989
Ensembl chr13:72,800,127...72,806,180
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G |
Gpsm2 |
G-protein signaling modulator 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPSM2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154
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G |
Gpt |
glutamic--pyruvic transaminase |
increases activity |
ISO |
T-2 Toxin results in increased activity of GPT protein |
CTD |
PMID:23929680 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression decreases expression decreases activity |
EXP ISO |
T-2 Toxin results in increased expression of GPX1 mRNA T-2 Toxin results in decreased expression of GPX1 mRNA T-2 Toxin results in decreased activity of GPX1 protein |
CTD |
PMID:26141394 PMID:27842451 PMID:29870751 PMID:30091165 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GPX2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Grb10 |
growth factor receptor bound protein 10 |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of GRB10 mRNA T-2 Toxin results in decreased expression of GRB10 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
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G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GRIA2 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
increases expression |
ISO |
T-2 Toxin results in increased expression of GRIN2A mRNA |
CTD |
PMID:26314264 |
|
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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G |
Grm4 |
glutamate metabotropic receptor 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GRM4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
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G |
Grn |
granulin precursor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GRN mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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G |
Gsdma |
gasdermin A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GSDMA mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:83,614,336...83,639,543
Ensembl chr10:83,627,051...83,639,543
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases expression increases expression multiple interactions |
EXP ISO |
T-2 Toxin results in decreased expression of GSK3B mRNA T-2 Toxin results in increased expression of GSK3B protein 3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of GSK3B protein] |
CTD |
PMID:26141394 PMID:35289972 PMID:36402210 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
decreases expression affects expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of GSR mRNA T-2 Toxin affects the expression of GSR mRNA T-2 Toxin affects the expression of and affects the activity of GSR protein |
CTD |
PMID:19526462 PMID:23929680 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gss |
glutathione synthetase |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of GSS protein T-2 Toxin results in increased expression of GSS mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
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G |
Gsto2 |
glutathione S-transferase omega 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of GSTO2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
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G |
Gstp1 |
glutathione S-transferase pi 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of GSTP1 protein |
CTD |
PMID:26141394 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt2 |
glutathione S-transferase theta 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of GSTT2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
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G |
H1f10 |
H1.10 linker histone |
increases expression |
EXP |
T-2 Toxin results in increased expression of H1F10 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448
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G |
H2ax |
H2A.X variant histone |
multiple interactions increases activity |
ISO |
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of H2AX protein] |
CTD |
PMID:20150440 |
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NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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G |
H6pd |
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of H6PD mRNA |
CTD |
PMID:26141394 |
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NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of HAPLN1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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G |
Has2 |
hyaluronan synthase 2 |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of HAS2 mRNA T-2 Toxin results in increased expression of HAS2 mRNA |
CTD |
PMID:18196609 PMID:31863870 |
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NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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G |
Hbs1l |
HBS1-like translational GTPase |
increases expression |
ISO |
T-2 Toxin results in increased expression of HBS1L mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:16,092,547...16,170,074
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G |
Hbz |
hemoglobin subunit zeta |
increases expression |
ISO |
T-2 Toxin results in increased expression of HBZ mRNA |
CTD |
PMID:34581912 |
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NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
increases expression |
EXP |
T-2 Toxin results in increased expression of HCK mRNA |
CTD |
PMID:26141394 |
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NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
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G |
Helq |
helicase, POLQ-like |
increases expression |
EXP |
T-2 Toxin results in increased expression of HELQ mRNA |
CTD |
PMID:26141394 |
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NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960
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G |
Hexim2 |
HEXIM P-TEFb complex subunit 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of HEXIM2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression |
ISO |
T-2 Toxin results in increased expression of HIF1A protein |
CTD |
PMID:36115646 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hipk3 |
homeodomain interacting protein kinase 3 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of HIPK3 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
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G |
Hist1h2bd |
histone cluster 1 H2B family member D |
increases expression |
ISO |
T-2 Toxin results in increased expression of H2BC5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr17:42,792,887...42,793,268
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G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of HMGA1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of HMGCR mRNA |
CTD |
PMID:22982764 PMID:34581912 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmox1 |
heme oxygenase 1 |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of HMOX1 mRNA; T-2 Toxin results in decreased expression of HMOX1 protein T-2 Toxin results in increased expression of HMOX1 mRNA |
CTD |
PMID:20854872 PMID:29432840 PMID:33508416 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPA2B1 protein |
CTD |
PMID:26141394 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPA3 protein |
CTD |
PMID:26141394 |
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NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
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G |
Hnrnpab |
heterogeneous nuclear ribonucleoprotein A/B |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPAB protein |
CTD |
PMID:26141394 |
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NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPH1 protein |
CTD |
PMID:26141394 |
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NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPK protein |
CTD |
PMID:26141394 |
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NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
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G |
Hp |
haptoglobin |
increases expression |
EXP |
T-2 Toxin results in increased expression of HP mRNA |
CTD |
PMID:26141394 |
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NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSP90AA1 protein |
CTD |
PMID:26141394 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
affects expression decreases expression |
EXP |
T-2 Toxin affects the expression of HSP90AB1 protein T-2 Toxin results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSP90B1 protein |
CTD |
PMID:26141394 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPA4 protein |
CTD |
PMID:26141394 |
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NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions affects expression increases expression |
ISO EXP |
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein]; T-2 Toxin results in increased degradation of and results in decreased expression of HSPA5 protein T-2 Toxin affects the expression of HSPA5 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein] T-2 Toxin results in increased expression of HSPA5 mRNA; T-2 Toxin results in increased expression of HSPA5 protein |
CTD |
PMID:19336499 PMID:26141394 PMID:29454614 PMID:31170431 PMID:34673134 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPA8 protein |
CTD |
PMID:26141394 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPA9 protein |
CTD |
PMID:26141394 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases expression |
ISO |
T-2 Toxin results in increased expression of and results in decreased phosphorylation of HSPB1 protein T-2 Toxin results in increased expression of HSPB1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPD1 protein |
CTD |
PMID:26141394 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Htra4 |
HtrA serine peptidase 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of HTRA4 mRNA |
CTD |
PMID:26141394 |
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NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
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G |
Hus1 |
HUS1 checkpoint clamp component |
increases expression |
EXP |
T-2 Toxin results in increased expression of HUS1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
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G |
Hyi |
hydroxypyruvate isomerase |
increases expression |
ISO |
T-2 Toxin results in increased expression of HYI mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:131,894,575...131,897,709
Ensembl chr 5:131,894,598...131,897,251
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ID2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of IDH1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
affects expression |
EXP |
T-2 Toxin affects the expression of IDH3A protein |
CTD |
PMID:26141394 |
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NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
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G |
Idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
increases expression |
ISO |
T-2 Toxin results in increased expression of IDH3B mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
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G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IER3 mRNA |
CTD |
PMID:34581912 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifitm10 |
interferon induced transmembrane protein 10 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of IFITM10 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151
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G |
Ifng |
interferon gamma |
increases expression |
ISO |
T-2 Toxin results in increased expression of IFNG protein |
CTD |
PMID:36115646 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IFRD1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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G |
Igf2bp2 |
insulin-like growth factor 2 mRNA binding protein 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IGF2BP2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:26141394 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbpl1 |
insulin-like growth factor binding protein-like 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IGFBPL1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833
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G |
Igflr1 |
IGF-like family receptor 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IGFLR1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:85,818,428...85,821,032
Ensembl chr 1:85,816,326...85,821,030
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G |
Ikzf3 |
IKAROS family zinc finger 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IKZF3 mRNA |
CTD |
PMID:34581912 |
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NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591
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G |
Il10 |
interleukin 10 |
affects expression decreases expression |
ISO |
T-2 Toxin affects the expression of IL10 mRNA T-2 Toxin results in decreased expression of IL10 mRNA; T-2 Toxin results in decreased expression of IL10 protein |
CTD |
PMID:22960706 PMID:31170431 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il11 |
interleukin 11 |
increases expression multiple interactions decreases methylation |
EXP |
T-2 Toxin results in increased expression of IL11 mRNA; T-2 Toxin results in increased expression of IL11 protein Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of IL11 promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL11 mRNA] |
CTD |
PMID:29079362 PMID:31279042 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il1a |
interleukin 1 alpha |
increases expression decreases methylation |
ISO EXP |
T-2 Toxin results in increased expression of IL1A mRNA T-2 Toxin results in decreased methylation of IL1A promoter |
CTD |
PMID:21112371 PMID:31279042 PMID:36775139 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; SB 203580 inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein] T-2 Toxin results in increased expression of IL1B mRNA; T-2 Toxin results in increased expression of IL1B protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA] |
CTD |
PMID:18196609 PMID:21112371 PMID:21453744 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
affects secretion increases expression |
ISO |
T-2 Toxin affects the secretion of IL2 protein T-2 Toxin results in increased expression of IL2 mRNA |
CTD |
PMID:8560498 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il20rb |
interleukin 20 receptor subunit beta |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of IL20RB mRNA |
CTD |
PMID:34581912 |
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NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942
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G |
Il22 |
interleukin 22 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IL22 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186
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G |
Il4 |
interleukin 4 |
affects secretion decreases expression |
ISO |
T-2 Toxin affects the secretion of IL4 protein T-2 Toxin results in decreased expression of IL4 mRNA |
CTD |
PMID:8560498 PMID:22960706 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
affects secretion |
ISO |
T-2 Toxin affects the secretion of IL5 protein |
CTD |
PMID:8560498 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression affects expression decreases methylation |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA] T-2 Toxin results in increased expression of IL6 mRNA; T-2 Toxin results in increased expression of IL6 protein AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 protein] T-2 Toxin affects the expression of IL6 mRNA T-2 Toxin results in decreased methylation of IL6 promoter |
CTD |
PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Imp4 |
IMP U3 small nucleolar ribonucleoprotein 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IMP4 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:36,654,401...36,660,075
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G |
Insig1 |
insulin induced gene 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of INSIG1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IRAK1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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Irak2 |
interleukin-1 receptor-associated kinase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IRAK2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
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G |
Islr |
immunoglobulin superfamily containing leucine-rich repeat |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ISLR mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130
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G |
Itga10 |
integrin subunit alpha 10 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGA10 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172
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G |
Itga11 |
integrin subunit alpha 11 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGA11 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407
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G |
Itgam |
integrin subunit alpha M |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of ITGAM protein Minocycline inhibits the reaction [T-2 Toxin results in increased expression of ITGAM protein] |
CTD |
PMID:36775139 |
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NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGB1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb5 |
integrin subunit beta 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGB5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
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Itgbl1 |
integrin subunit beta like 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGBL1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733
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G |
Jag1 |
jagged canonical Notch ligand 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of JAG1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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G |
Jag2 |
jagged canonical Notch ligand 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of JAG2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
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G |
Jak1 |
Janus kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of JAK1 mRNA |
CTD |
PMID:22454431 |
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NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression decreases expression |
ISO |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] T-2 Toxin results in decreased expression of JAK2 mRNA |
CTD |
PMID:22454431 PMID:34581912 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jam3 |
junctional adhesion molecule 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of JAM3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
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G |
Jdp2 |
Jun dimerization protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of JDP2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of JUN mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcnc3 |
potassium voltage-gated channel subfamily C member 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of KCNC3 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160
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G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of KCNMA1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
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G |
Kdelr2 |
KDEL endoplasmic reticulum protein retention receptor 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KDELR2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
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G |
Kdelr3 |
KDEL endoplasmic reticulum protein retention receptor 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KDELR3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600
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G |
Kdm4d |
lysine demethylase 4D |
increases expression |
ISO |
T-2 Toxin results in increased expression of KDM4D mRNA |
CTD |
PMID:34581912 |
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NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KEAP1 mRNA; T-2 Toxin results in decreased expression of KEAP1 protein |
CTD |
PMID:35842139 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Kiaa0232 |
KIAA0232 homolog |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KIAA0232 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:74,094,421...74,159,316
Ensembl chr14:74,094,488...74,159,326
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G |
Kif16b |
kinesin family member 16B |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of KIF16B mRNA |
CTD |
PMID:26141394 |
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NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
T-2 Toxin results in increased expression of KIT mRNA |
CTD |
PMID:34581912 |
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NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Kitlg |
KIT ligand |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KITLG mRNA; T-2 Toxin results in decreased expression of KITLG protein |
CTD |
PMID:26314264 |
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NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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G |
Klf6 |
KLF transcription factor 6 |
increases expression |
ISO |
T-2 Toxin results in increased expression of KLF6 mRNA |
CTD |
PMID:34581912 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Krt1 |
keratin 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of KRT1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
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G |
Krt8 |
keratin 8 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of KRT8 protein T-2 Toxin results in increased expression of KRT8 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Lama5 |
laminin subunit alpha 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of LAMA5 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
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G |
Lars1 |
leucyl-tRNA synthetase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of LARS1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
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G |
Lbh |
LBH regulator of WNT signaling pathway |
increases expression |
ISO |
T-2 Toxin results in increased expression of LBH mRNA |
CTD |
PMID:34581912 |
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NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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G |
Lcp2 |
lymphocyte cytosolic protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of LCP2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559
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G |
Ldha |
lactate dehydrogenase A |
increases expression |
ISO |
T-2 Toxin results in increased expression of LDHA protein |
CTD |
PMID:36115646 |
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NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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G |
Lgals1 |
galectin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of LGALS1 protein |
CTD |
PMID:26141394 |
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NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of LGR5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
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G |
Lhb |
luteinizing hormone subunit beta |
decreases expression increases secretion |
EXP |
T-2 Toxin results in decreased expression of LHB protein T-2 Toxin results in increased secretion of LHB protein |
CTD |
PMID:26569305 PMID:26847343 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions |
ISO |
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA] |
CTD |
PMID:30951242 |
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NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Lin28a |
lin-28 homolog A |
increases expression |
ISO |
T-2 Toxin results in increased expression of LIN28A mRNA |
CTD |
PMID:34581912 |
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NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
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G |
LOC100909998 |
zinc finger protein 2-like |
increases expression |
ISO |
T-2 Toxin results in increased expression of ZNF2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 3:114,793,783...114,818,395
Ensembl chr 3:114,809,723...114,818,387 Ensembl chr 3:114,809,723...114,818,387
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G |
Lrpap1 |
LDL receptor related protein associated protein 1 |
affects expression decreases expression |
EXP ISO |
T-2 Toxin affects the expression of LRPAP1 protein T-2 Toxin results in decreased expression of LRPAP1 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
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NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
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G |
Ltbp2 |
latent transforming growth factor beta binding protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of LTBP2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
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G |
Lyz2 |
lysozyme 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of LYZ mRNA |
CTD |
PMID:34581912 |
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NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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G |
Macf1 |
microtubule-actin crosslinking factor 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MACF1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
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G |
Map1b |
microtubule-associated protein 1B |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MAP1B mRNA |
CTD |
PMID:34581912 |
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NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression multiple interactions affects expression |
EXP ISO |
T-2 Toxin results in increased expression of MAP1LC3B mRNA T-2 Toxin results in increased expression of and results in increased cleavage of MAP1LC3B protein T-2 Toxin affects the expression of MAP1LC3B protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of MAP1LC3B protein] |
CTD |
PMID:29413859 PMID:36402210 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
T-2 Toxin results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:36775139 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
T-2 Toxin results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:36775139 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk8ip1 |
mitogen-activated protein kinase 8 interacting protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MAPK8IP1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
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G |
Mars2 |
methionyl-tRNA synthetase 2, mitochondrial |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of MARS2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:56,720,983...56,723,820
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G |
Mat2a |
methionine adenosyltransferase 2A |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MAT2A mRNA |
CTD |
PMID:34581912 |
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NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
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G |
Mbtps1 |
membrane-bound transcription factor peptidase, site 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MBTPS1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
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NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
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G |
Mcf2l |
MCF.2 cell line derived transforming sequence-like |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of MCF2L mRNA |
CTD |
PMID:26141394 |
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NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
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G |
Mcm7 |
minichromosome maintenance complex component 7 |
affects expression |
EXP |
T-2 Toxin affects the expression of MCM7 protein |
CTD |
PMID:26141394 |
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NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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G |
Mdh1 |
malate dehydrogenase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of MDH1 protein |
CTD |
PMID:26141394 |
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NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
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G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of MDM2 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Megf6 |
multiple EGF-like-domains 6 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MEGF6 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139
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G |
Meltf |
melanotransferrin |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MELTF mRNA |
CTD |
PMID:31863870 |
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NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
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G |
Mesd |
mesoderm development LRP chaperone |
affects expression |
EXP |
T-2 Toxin affects the expression of MESD protein |
CTD |
PMID:26141394 |
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NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999
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G |
Metrnl |
meteorin-like, glial cell differentiation regulator |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of METRNL mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
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G |
Mettl9 |
methyltransferase 9, His-X-His N1(pi)-histidine |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of METTL9 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:175,577,890...175,623,061
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G |
Mfge8 |
milk fat globule EGF and factor V/VIII domain containing |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MFGE8 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
EXP |
PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA] |
CTD |
PMID:36863559 |
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NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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G |
Mir155 |
microRNA 155 |
multiple interactions increases expression |
ISO |
MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] T-2 Toxin results in increased expression of MIR155 mRNA |
CTD |
PMID:32240701 |
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NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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Mknk2 |
MAPK interacting serine/threonine kinase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MKNK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
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Mmd |
monocyte to macrophage differentiation-associated |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of MMD mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528
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Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MMP1 protein |
CTD |
PMID:21144892 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp12 |
matrix metallopeptidase 12 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MMP12 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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Mmp13 |
matrix metallopeptidase 13 |
multiple interactions increases expression |
ISO EXP |
4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein] T-2 Toxin results in increased expression of MMP13 mRNA; T-2 Toxin results in increased expression of MMP13 protein [salubrinal co-treated with T-2 Toxin] results in increased expression of MMP13 mRNA; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein] |
CTD |
PMID:21144892 PMID:22800716 PMID:34673134 PMID:35213812 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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Mmp2 |
matrix metallopeptidase 2 |
increases activity decreases expression |
ISO |
T-2 Toxin results in increased activity of MMP2 protein T-2 Toxin results in decreased expression of MMP2 mRNA |
CTD |
PMID:21112371 PMID:22960706 |
|
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp3 |
matrix metallopeptidase 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MMP3 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp9 |
matrix metallopeptidase 9 |
affects expression increases activity multiple interactions increases expression |
ISO EXP |
T-2 Toxin affects the expression of MMP9 mRNA T-2 Toxin results in increased activity of MMP9 protein T-2 Toxin results in increased expression of and results in increased activity of MMP9 protein T-2 Toxin results in increased expression of MMP9 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA] |
CTD |
PMID:21112371 PMID:22800716 PMID:22960706 PMID:29079362 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mpdu1 |
mannose-P-dolichol utilization defect 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MPDU1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447
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Mphosph9 |
M-phase phosphoprotein 9 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MPHOSPH9 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:32,275,449...32,346,097
Ensembl chr12:32,275,558...32,342,392
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Mpo |
myeloperoxidase |
increases activity |
ISO |
T-2 Toxin results in increased activity of MPO protein |
CTD |
PMID:22960706 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mpst |
mercaptopyruvate sulfurtransferase |
affects expression |
EXP |
T-2 Toxin affects the expression of MPST protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141
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Mrap2 |
melanocortin 2 receptor accessory protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MRAP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886
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Mre11 |
MRE11 homolog, double strand break repair nuclease |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MRE11A mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
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G |
Mrpl58 |
mitochondrial ribosomal protein L58 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MRPL58 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:100,646,374...100,652,871
Ensembl chr10:100,646,216...100,652,871
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G |
Mrps18c |
mitochondrial ribosomal protein S18C |
increases expression |
ISO |
T-2 Toxin results in increased expression of MRPS18C mRNA |
CTD |
PMID:31863870 |
|
NCBI chr14:8,812,301...8,818,538
Ensembl chr14:8,791,330...8,818,516
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G |
Mrps22 |
mitochondrial ribosomal protein S22 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MRPS22 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291
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Ms4a3 |
membrane spanning 4-domains A3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MS4A3 mRNA; T-2 Toxin results in decreased expression of MS4A3 protein |
CTD |
PMID:34581912 |
|
NCBI chr 1:208,462,300...208,480,129
Ensembl chr 1:208,462,301...208,480,101
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G |
Msmo1 |
methylsterol monooxygenase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MSMO1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP6 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
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Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ATP8 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
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Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression |
EXP |
T-2 Toxin results in increased expression of COX1 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
increases expression |
EXP |
T-2 Toxin results in increased expression of COX2 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
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Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
increases expression |
EXP |
T-2 Toxin results in increased expression of COX3 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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Mt-cyb |
mitochondrially encoded cytochrome b |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CYTB mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
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Mt-nd3 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ND3 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
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Mt-nd5 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ND5 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
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G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ND6 mRNA |
CTD |
PMID:29870751 |
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NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
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Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of MTHFD2 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
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NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
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G |
Mtor |
mechanistic target of rapamycin kinase |
affects expression |
EXP |
T-2 Toxin affects the expression of MTOR protein |
CTD |
PMID:29413859 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Mtpn |
myotrophin |
affects expression |
EXP |
T-2 Toxin affects the expression of MTPN protein |
CTD |
PMID:26141394 |
|
NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
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G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions decreases expression |
ISO |
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein] |
CTD |
PMID:31170431 |
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NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
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Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MYC mRNA |
CTD |
PMID:35289972 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nanos1 |
nanos C2HC-type zinc finger 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NANOS1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of NARS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
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G |
Ndufa1 |
NADH:ubiquinone oxidoreductase subunit A1 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1] |
CTD |
PMID:36863559 |
|
NCBI chr X:116,424,223...116,427,875
Ensembl chr X:116,424,223...116,428,633
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G |
Ndufa12 |
NADH:ubiquinone oxidoreductase subunit A12 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12] |
CTD |
PMID:36863559 |
|
NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315
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G |
Ndufa4 |
Ndufa4, mitochondrial complex associated |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4] |
CTD |
PMID:36863559 |
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NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
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G |
Ndufa9 |
NADH:ubiquinone oxidoreductase subunit A9 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9] |
CTD |
PMID:36863559 |
|
NCBI chr 4:159,659,242...159,688,034
Ensembl chr 4:159,659,242...159,688,018
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G |
Ndufaf1 |
NADH:ubiquinone oxidoreductase complex assembly factor 1 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFAF1 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1] |
CTD |
PMID:29870751 PMID:36863559 |
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NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212
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G |
Ndufaf2 |
NADH:ubiquinone oxidoreductase complex assembly factor 2 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFAF2 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316
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Ndufaf3 |
NADH:ubiquinone oxidoreductase complex assembly factor 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFAF3 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 8:109,261,362...109,263,194
Ensembl chr 8:109,261,363...109,263,194
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G |
Ndufaf4 |
NADH:ubiquinone oxidoreductase complex assembly factor 4 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFAF4 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4] |
CTD |
PMID:29870751 PMID:36863559 |
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NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336
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Ndufb2 |
NADH:ubiquinone oxidoreductase subunit B2 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2] |
CTD |
PMID:36863559 |
|
NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851 Ensembl chr 4:46,536,062...46,536,851
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G |
Ndufb3 |
NADH:ubiquinone oxidoreductase subunit B3 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3] |
CTD |
PMID:36863559 |
|
NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446
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G |
Ndufb4 |
NADH:ubiquinone oxidoreductase subunit B4 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4] |
CTD |
PMID:36863559 |
|
NCBI chr11:63,063,723...63,070,426
Ensembl chr11:63,063,795...63,070,425
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G |
Ndufb5 |
NADH:ubiquinone oxidoreductase subunit B5 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5] |
CTD |
PMID:36863559 |
|
NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
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Ndufb7 |
NADH:ubiquinone oxidoreductase subunit B7 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7] |
CTD |
PMID:36863559 |
|
NCBI chr19:24,568,241...24,572,579
Ensembl chr19:24,568,241...24,572,579
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G |
Ndufs1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
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G |
Ndufs3 |
NADH:ubiquinone oxidoreductase core subunit S3 |
affects expression increases expression multiple interactions |
EXP |
T-2 Toxin affects the expression of NDUFS3 protein T-2 Toxin results in increased expression of NDUFS3 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3] |
CTD |
PMID:26141394 PMID:29870751 PMID:36863559 |
|
NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
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G |
Ndufs4 |
NADH:ubiquinone oxidoreductase subunit S4 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS4 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
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G |
Ndufs5 |
NADH:ubiquinone oxidoreductase subunit S5 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of NDUFS5 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603 Ensembl chr14:135,974,034...135,979,603 Ensembl chr 2:135,974,034...135,979,603
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Ndufs6 |
NADH:ubiquinone oxidoreductase subunit S6 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS6 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467
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Ndufs7 |
NADH:ubiquinone oxidoreductase core subunit S7 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFS7 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7] |
CTD |
PMID:29870751 PMID:36863559 |
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NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195
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G |
Ndufs8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS8 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
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G |
Ndufv1 |
NADH:ubiquinone oxidoreductase core subunit V1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFV1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466
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G |
Ndufv2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFV2 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
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G |
Ndufv3 |
NADH:ubiquinone oxidoreductase subunit V3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFV3 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074 Ensembl chr13:9,612,431...9,623,074
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G |
Nefh |
neurofilament heavy chain |
increases expression |
ISO |
T-2 Toxin results in increased expression of NEFH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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G |
Nelfe |
negative elongation factor complex member E |
increases expression |
ISO |
T-2 Toxin results in increased expression of NELFE mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases expression increases expression multiple interactions |
ISO EXP |
T-2 Toxin results in decreased expression of NFE2L2 mRNA; T-2 Toxin results in decreased expression of NFE2L2 protein T-2 Toxin results in increased expression of NFE2L2 protein N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein] T-2 Toxin results in increased expression of NFE2L2 mRNA; T-2 Toxin results in increased expression of NFE2L2 protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein] |
CTD |
PMID:20854872 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35842139 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions increases phosphorylation |
ISO |
BAY 11-7085 inhibits the reaction [T-2 Toxin results in decreased expression of and results in increased degradation of NFKBIA protein]; T-2 Toxin results in increased degradation of and results in decreased expression of NFKBIA protein T-2 Toxin results in increased phosphorylation of NFKBIA protein |
CTD |
PMID:22800716 PMID:36775139 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbil1 |
NFKB inhibitor like 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NFKBIL1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
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G |
Nfrkb |
nuclear factor related to kappa B binding protein |
increases expression |
EXP |
T-2 Toxin results in increased expression of NFRKB mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359
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G |
Nhej1 |
nonhomologous end-joining factor 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NHEJ1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444
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G |
Niban1 |
niban apoptosis regulator 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NIBAN1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
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G |
Nme2 |
NME/NM23 nucleoside diphosphate kinase 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of NME2 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 Ensembl chr20:78,897,770...78,903,538
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G |
Nol9 |
nucleolar protein 9 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOL9 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:162,546,522...162,566,625
Ensembl chr 5:162,546,541...162,566,191
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G |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOLC1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
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G |
Nop14 |
NOP14 nucleolar protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOP14 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:76,081,313...76,102,454
Ensembl chr14:76,080,793...76,102,453
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G |
Nop2 |
NOP2 nucleolar protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOP2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOS2 mRNA |
CTD |
PMID:21112371 PMID:22960706 PMID:36775139 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NOS3 mRNA |
CTD |
PMID:22960706 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch1 |
notch receptor 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NOTCH1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Npm1 |
nucleophosmin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of NPM1 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 Ensembl chr X:17,739,941...17,751,645
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G |
Nptxr |
neuronal pentraxin receptor |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of NPTXR mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
decreases expression increases expression |
ISO EXP |
T-2 Toxin results in decreased expression of NQO1 mRNA T-2 Toxin results in increased expression of NQO1 mRNA |
CTD |
PMID:20854872 PMID:26141394 PMID:33508416 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nqo2 |
N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NQO2 protein |
CTD |
PMID:34581912 |
|
NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NR0B1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NR4A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NR5A1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G |
Nrf1 |
nuclear respiratory factor 1 |
decreases expression multiple interactions affects expression |
ISO EXP |
T-2 Toxin results in decreased expression of NRF1 protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of NRF1 protein] T-2 Toxin affects the expression of NRF1 mRNA NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter] T-2 Toxin results in decreased expression of NRF1 mRNA; T-2 Toxin results in decreased expression of NRF1 protein |
CTD |
PMID:27363784 PMID:29870751 PMID:31470059 PMID:35842139 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Nrip3 |
nuclear receptor interacting protein 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NRIP3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600
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G |
Nsfl1c |
NSFL1 cofactor |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C] |
CTD |
PMID:36863559 |
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NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870
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G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NTRK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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G |
Nucb1 |
nucleobindin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of NUCB1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
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G |
Nucb2 |
nucleobindin 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NUCB2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NUF2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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G |
Nup43 |
nucleoporin 43 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NUP43 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186
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G |
Oat |
ornithine aminotransferase |
affects expression |
EXP |
T-2 Toxin affects the expression of OAT protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ocln |
occludin |
multiple interactions decreases expression |
ISO |
illite inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA] T-2 Toxin results in decreased expression of OCLN mRNA; T-2 Toxin results in decreased expression of OCLN protein |
CTD |
PMID:27153755 PMID:31170431 |
|
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
EXP |
PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA] |
CTD |
PMID:36863559 |
|
NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
Ostm1 |
osteoclastogenesis associated transmembrane protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of OSTM1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023
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G |
P4hb |
prolyl 4-hydroxylase subunit beta |
affects expression |
EXP |
T-2 Toxin affects the expression of P4HB protein |
CTD |
PMID:26141394 |
|
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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G |
Pa2g4 |
proliferation-associated 2G4 |
affects expression |
EXP |
T-2 Toxin affects the expression of PA2G4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
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G |
Pafah1b2 |
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PAFAH1B2 protein |
CTD |
PMID:34581912 |
|
NCBI chr 8:46,260,069...46,312,073
Ensembl chr 8:46,261,064...46,279,833
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G |
Parg |
poly (ADP-ribose) glycohydrolase |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to PARG] |
CTD |
PMID:36863559 |
|
NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
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G |
Park7 |
Parkinsonism associated deglycase |
affects expression |
EXP |
T-2 Toxin affects the expression of PARK7 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PARP1 mRNA; T-2 Toxin results in increased expression of PARP1 protein |
CTD |
PMID:28697680 PMID:29432840 |
|
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pax6 |
paired box 6 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PAX6 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PCK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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G |
Pcna |
proliferating cell nuclear antigen |
affects expression |
EXP |
T-2 Toxin affects the expression of PCNA protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcsk5 |
proprotein convertase subtilisin/kexin type 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PCSK5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600
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G |
Pcyox1l |
prenylcysteine oxidase 1 like |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PCYOX1L mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327
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G |
Pdcd10 |
programmed cell death 10 |
affects expression |
EXP |
T-2 Toxin affects the expression of PDCD10 protein |
CTD |
PMID:26141394 |
|
NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
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G |
Pdcd4 |
programmed cell death 4 |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of PDCD4 mRNA T-2 Toxin results in decreased expression of PDCD4 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
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G |
Pdcd7 |
programmed cell death 7 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PDCD7 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:65,862,606...65,877,333
Ensembl chr 8:65,862,387...65,877,333
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G |
Pde10a |
phosphodiesterase 10A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PDE10A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
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G |
Pde4b |
phosphodiesterase 4B |
increases expression |
ISO |
T-2 Toxin results in increased expression of PDE4B mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
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G |
Pdgfa |
platelet derived growth factor subunit A |
increases expression |
ISO |
T-2 Toxin results in increased expression of PDGFA mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdgfrl |
platelet-derived growth factor receptor-like |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PDGFRL mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
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G |
Pdhb |
pyruvate dehydrogenase E1 subunit beta |
affects expression |
EXP |
T-2 Toxin affects the expression of PDHB protein |
CTD |
PMID:26141394 |
|
NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
affects expression |
EXP |
T-2 Toxin affects the expression of PDIA3 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PDIA4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pdlim1 |
PDZ and LIM domain 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PDLIM1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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G |
Pdrg1 |
p53 and DNA damage regulated 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PDRG1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858 Ensembl chr 3:141,476,501...141,483,858
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G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PEA15 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
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G |
Pes1 |
pescadillo ribosomal biogenesis factor 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PES1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:78,850,754...78,867,134
Ensembl chr14:78,850,709...78,867,134
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G |
Pex5 |
peroxisomal biogenesis factor 5 |
multiple interactions increases expression |
EXP |
GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5] |
CTD |
PMID:36863559 |
|
NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431
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G |
Pfn1 |
profilin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of PFN1 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
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G |
Pgam1 |
phosphoglycerate mutase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of PGAM1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
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G |
Pgk1 |
phosphoglycerate kinase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of PGK1 protein |
CTD |
PMID:26141394 |
|
NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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G |
Pgls |
6-phosphogluconolactonase |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of PGLS protein T-2 Toxin results in increased expression of PGLS protein |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
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G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA] |
CTD |
PMID:30951242 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Phb1 |
prohibitin 1 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of PHB1 protein T-2 Toxin results in increased expression of PHB1 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
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NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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G |
Phgdh |
phosphoglycerate dehydrogenase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PHGDH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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G |
Phlda1 |
pleckstrin homology-like domain, family A, member 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PHLDA1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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G |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PIK3CB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
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G |
Pik3r2 |
phosphoinositide-3-kinase regulatory subunit 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PIK3R2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
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G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PIK3R3 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions increases expression |
EXP |
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA] T-2 Toxin results in increased expression of PINK1 mRNA; T-2 Toxin results in increased expression of PINK1 protein |
CTD |
PMID:29870751 PMID:36863559 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Pkib |
cAMP-dependent protein kinase inhibitor beta |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PKIB mRNA |
CTD |
PMID:26141394 |
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NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
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G |
Pkig |
cAMP-dependent protein kinase inhibitor gamma |
affects expression |
EXP |
T-2 Toxin affects the expression of PKIG protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:152,330,477...152,398,085
Ensembl chr 3:152,366,041...152,398,082
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G |
Pkm |
pyruvate kinase M1/2 |
affects expression |
EXP |
T-2 Toxin affects the expression of PKM protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Plekha1 |
pleckstrin homology domain containing A1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PLEKHA1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
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G |
Plxna4 |
plexin A4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PLXNA4 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206
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G |
Polr2e |
RNA polymerase II, I and III subunit E |
increases expression |
ISO |
T-2 Toxin results in increased expression of POLR2E mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643
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G |
Polr3c |
RNA polymerase III subunit C |
increases expression |
ISO |
T-2 Toxin results in increased expression of POLR3C mRNA |
CTD |
PMID:34581912 |
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NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208
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G |
Pop4 |
POP4 homolog, ribonuclease P/MRP subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of POP4 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443
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G |
Pou1f1 |
POU class 1 homeobox 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of POU1F1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
EXP |
T-2 Toxin results in increased expression of PPARG mRNA |
CTD |
PMID:26141394 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression multiple interactions increases expression |
ISO EXP |
T-2 Toxin results in decreased expression of PPARGC1A protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein] T-2 Toxin results in increased expression of PPARGC1A mRNA T-2 Toxin results in decreased expression of PPARGC1A mRNA; T-2 Toxin results in decreased expression of PPARGC1A protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein] |
CTD |
PMID:27363784 PMID:29870751 PMID:35842139 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppargc1b |
PPARG coactivator 1 beta |
increases expression |
EXP |
T-2 Toxin results in increased expression of PPARGC1B mRNA |
CTD |
PMID:29870751 |
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NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
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G |
Ppcs |
phosphopantothenoylcysteine synthetase |
increases expression |
ISO |
T-2 Toxin results in increased expression of PPCS mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
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G |
Ppia |
peptidylprolyl isomerase A |
affects expression |
EXP |
T-2 Toxin affects the expression of PPIA protein |
CTD |
PMID:26141394 |
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NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PPP1R10 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
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G |
Ppp3cb |
protein phosphatase 3 catalytic subunit beta |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PPP3CB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
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G |
Pprc1 |
PPARG related coactivator 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PPRC1 mRNA |
CTD |
PMID:29870751 |
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NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
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G |
Prcp |
prolylcarboxypeptidase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PRCP mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530
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G |
Prdx3 |
peroxiredoxin 3 |
affects expression decreases expression |
EXP ISO |
T-2 Toxin affects the expression of PRDX3 protein T-2 Toxin results in decreased expression of PRDX3 mRNA; T-2 Toxin results in decreased expression of PRDX3 protein |
CTD |
PMID:26141394 PMID:34581912 |
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NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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G |
Prdx4 |
peroxiredoxin 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of PRDX4 protein |
CTD |
PMID:26141394 |
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NCBI chr X:40,026,762...40,044,066
Ensembl chr X:40,026,651...40,044,066
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G |
Prelp |
proline and arginine rich end leucine rich repeat protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PRELP mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
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G |
Prickle2 |
prickle planar cell polarity protein 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PRICKLE2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:124,869,655...125,214,862
Ensembl chr 4:124,869,552...125,214,824
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G |
Prkcb |
protein kinase C, beta |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PRKCB mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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G |
Prkcz |
protein kinase C, zeta |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PRKCZ mRNA |
CTD |
PMID:26141394 |
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NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
increases expression |
EXP |
T-2 Toxin results in increased expression of PRKN mRNA; T-2 Toxin results in increased expression of PRKN protein |
CTD |
PMID:29870751 |
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NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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G |
Prmt5 |
protein arginine methyltransferase 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PRMT5 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
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G |
Prpf6 |
pre-mRNA processing factor 6 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PRPF6 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991
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G |
Psat1 |
phosphoserine aminotransferase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PSAT1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
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NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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G |
Psma4 |
proteasome 20S subunit alpha 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMA4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
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G |
Psma6 |
proteasome 20S subunit alpha 6 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMA6 protein |
CTD |
PMID:26141394 |
|
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
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G |
Psmb3 |
proteasome 20S subunit beta 3 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMB3 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
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G |
Psmb7 |
proteasome 20S subunit beta 7 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMB7 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
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G |
Psmc2 |
proteasome 26S subunit, ATPase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PSMC2 mRNA; T-2 Toxin results in increased expression of PSMC2 protein |
CTD |
PMID:34581912 |
|
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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G |
Psmd9 |
proteasome 26S subunit, non-ATPase 9 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PSMD9 mRNA |
CTD |
PMID:26141394 |
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NCBI chr12:33,337,182...33,357,468
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G |
Psme3 |
proteasome activator subunit 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PSME3 protein |
CTD |
PMID:34581912 |
|
NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
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G |
Ptgis |
prostaglandin I2 synthase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PTGIS mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of PTGS2 mRNA; T-2 Toxin results in increased expression of PTGS2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:36115646 PMID:36775139 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptprc |
protein tyrosine phosphatase, receptor type, C |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PTPRC mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
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G |
Ptprf |
protein tyrosine phosphatase, receptor type, F |
increases expression |
ISO |
T-2 Toxin results in increased expression of PTPRF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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G |
Pxn |
paxillin |
increases expression |
ISO |
T-2 Toxin results in increased expression of PXN mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
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G |
Pyy |
peptide YY |
increases expression |
ISO |
T-2 Toxin results in increased expression of PYY protein alternative form |
CTD |
PMID:29689362 |
|
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
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G |
Qsox1 |
quiescin sulfhydryl oxidase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of QSOX1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
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G |
Qsox2 |
quiescin sulfhydryl oxidase 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of QSOX2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:9,034,994...9,064,649
Ensembl chr 3:9,034,994...9,064,664
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G |
Rab20 |
RAB20, member RAS oncogene family |
increases expression |
ISO |
T-2 Toxin results in increased expression of RAB20 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529
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G |
Rab25 |
RAB25, member RAS oncogene family |
increases expression |
EXP |
T-2 Toxin results in increased expression of RAB25 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:174,000,323...174,006,422
Ensembl chr 2:174,000,323...174,006,422
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G |
Rab27a |
RAB27A, member RAS oncogene family |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RAB27A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
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G |
Ramp1 |
receptor activity modifying protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RAMP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
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G |
Ranbp1 |
RAN binding protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of RANBP1 protein |
CTD |
PMID:26141394 |
|
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
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G |
Rasal3 |
RAS protein activator like 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RASAL3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:11,396,090...11,411,465
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G |
Rasd1 |
ras related dexamethasone induced 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RASD1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
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G |
Rassf1 |
Ras association domain family member 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RASSF1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164
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G |
Rassf4 |
Ras association domain family member 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RASSF4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases phosphorylation decreases expression |
EXP |
T-2 Toxin results in decreased phosphorylation of RB1 protein T-2 Toxin results in decreased expression of RB1 mRNA |
CTD |
PMID:29567467 |
|
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Rbks |
ribokinase |
increases expression |
EXP |
T-2 Toxin results in increased expression of RBKS mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290
|
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G |
Rbpms2 |
RNA binding protein, mRNA processing factor 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RBPMS2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268
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G |
Rcn1 |
reticulocalbin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of RCN1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295
|
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions affects localization increases expression |
EXP ISO |
T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter] T-2 Toxin affects the localization of RELA protein modified form T-2 Toxin results in increased expression of RELA mRNA |
CTD |
PMID:29079362 PMID:34581912 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Relb |
RELB proto-oncogene, NF-kB subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of RELB mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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G |
Reln |
reelin |
increases expression |
ISO |
T-2 Toxin results in increased expression of RELN mRNA |
CTD |
PMID:26314264 |
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NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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G |
Rgs12 |
regulator of G-protein signaling 12 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RGS12 mRNA |
CTD |
PMID:26141394 |
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NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596
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G |
Rgs2 |
regulator of G-protein signaling 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RGS2 mRNA |
CTD |
PMID:26141394 |
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NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
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G |
Rgs4 |
regulator of G-protein signaling 4 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RGS4 mRNA |
CTD |
PMID:26141394 |
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NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
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G |
Rheb |
Ras homolog, mTORC1 binding |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of RHEB mRNA; T-2 Toxin results in increased expression of RHEB protein MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] |
CTD |
PMID:32240701 |
|
NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
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G |
Rhob |
ras homolog family member B |
increases expression |
ISO |
T-2 Toxin results in increased expression of RHOB mRNA |
CTD |
PMID:34581912 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Rhoh |
ras homolog family member H |
increases expression |
EXP |
T-2 Toxin results in increased expression of RHOH mRNA |
CTD |
PMID:26141394 |
|
NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369
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G |
Rlig1 |
RNA 5'-phosphate and 3'-OH ligase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RLIG1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:35,396,876...35,408,633
Ensembl chr 7:35,397,995...35,409,600
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G |
Rp9 |
RP9, pre-mRNA splicing factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of RP9 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175
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G |
Rpap1 |
RNA polymerase II associated protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPAP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:106,746,642...106,768,182
Ensembl chr 3:106,656,742...106,768,151
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G |
Rpia |
ribose 5-phosphate isomerase A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RPIA mRNA |
CTD |
PMID:26141394 |
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NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
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G |
Rplp2 |
ribosomal protein lateral stalk subunit P2 |
affects expression |
EXP |
T-2 Toxin affects the expression of RPLP2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
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G |
Rpn2 |
ribophorin II |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RPN2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
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G |
Rpp21 |
ribonuclease P/MRP subunit p21 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPP21 mRNA |
CTD |
PMID:34581912 |
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NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106
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G |
Rpp25 |
ribonuclease P and MRP subunit p25 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPP25 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732
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G |
Rpp40 |
ribonuclease P/MRP subunit p40 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPP40 mRNA |
CTD |
PMID:34581912 |
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NCBI chr17:28,947,752...28,956,788
Ensembl chr17:28,947,734...28,956,788
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G |
Rps21-ps1 |
ribosomal protein S21, pseudogene 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of RPS21 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427
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G |
Rps6ka5 |
ribosomal protein S6 kinase A5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RPS6KA5 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
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G |
Rpsa |
ribosomal protein SA |
affects expression |
EXP |
T-2 Toxin affects the expression of RPSA protein |
CTD |
PMID:26141394 |
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NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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G |
Runx2 |
RUNX family transcription factor 2 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of RUNX2 mRNA; T-2 Toxin results in decreased expression of RUNX2 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of RUNX2 protein] |
CTD |
PMID:35289972 PMID:36402210 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Ruvbl1 |
RuvB-like AAA ATPase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RUVBL1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
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NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
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G |
Ruvbl2 |
RuvB-like AAA ATPase 2 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of RUVBL2 protein T-2 Toxin results in increased expression of RUVBL2 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
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NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
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G |
Safb |
scaffold attachment factor B |
increases expression |
EXP |
T-2 Toxin results in increased expression of SAFB mRNA |
CTD |
PMID:26141394 |
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NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644
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G |
Sap30bp |
SAP30 binding protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of SAP30BP mRNA |
CTD |
PMID:34581912 |
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NCBI chr10:101,165,777...101,198,503
Ensembl chr10:101,165,856...101,198,502
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G |
Scpep1 |
serine carboxypeptidase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SCPEP1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
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G |
Sdha |
succinate dehydrogenase complex flavoprotein subunit A |
increases expression |
EXP |
T-2 Toxin results in increased expression of SDHA mRNA |
CTD |
PMID:29870751 |
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NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
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G |
Sdhb |
succinate dehydrogenase complex iron sulfur subunit B |
increases expression |
EXP |
T-2 Toxin results in increased expression of SDHB mRNA |
CTD |
PMID:29870751 |
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NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
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G |
Selenos |
selenoprotein S |
increases expression |
ISO |
T-2 Toxin results in increased expression of SELS mRNA |
CTD |
PMID:34581912 |
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NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833
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G |
Sema3f |
semaphorin 3F |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SEMA3F mRNA |
CTD |
PMID:26141394 |
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NCBI chr 8:108,357,629...108,386,569
Ensembl chr 8:108,357,629...108,387,083
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G |
Serpina3n |
serpin family A member 3N |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SERPINA3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
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G |
Serpinb9 |
serpin family B member 9 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SERPINB9 protein |
CTD |
PMID:34581912 |
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NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
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G |
Serpine2 |
serpin family E member 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SERPINE2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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G |
Set |
Set nuclear proto-oncogene |
affects expression |
EXP |
T-2 Toxin affects the expression of SET protein |
CTD |
PMID:26141394 |
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NCBI chr 3:13,334,564...13,345,598
Ensembl chr 3:13,335,041...13,363,567
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G |
Setdb1 |
SET domain bifurcated histone lysine methyltransferase 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of SETDB1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506
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G |
Sf3b2 |
splicing factor 3b, subunit 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SF3B2 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SGK1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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G |
Sgms1 |
sphingomyelin synthase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SGMS1 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
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G |
Sh3gl1 |
SH3 domain containing GRB2 like 1, endophilin A2 |
affects expression |
EXP |
T-2 Toxin affects the expression of SH3GL1 protein |
CTD |
PMID:26141394 |
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NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
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G |
Skp1 |
S-phase kinase-associated protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of SKP1 protein |
CTD |
PMID:26141394 |
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NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388
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G |
Slc17a5 |
solute carrier family 17 member 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC17A5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:79,394,416...79,429,387
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G |
Slc17a6 |
solute carrier family 17 member 6 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC17A6 mRNA |
CTD |
PMID:26314264 |
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NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
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G |
Slc1a5 |
solute carrier family 1 member 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC1A5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
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G |
Slc27a5 |
solute carrier family 27 member 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of SLC27A5 mRNA |
CTD |
PMID:26141394 |
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NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
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G |
Slc29a4 |
solute carrier family 29 member 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SLC29A4 mRNA |
CTD |
PMID:26141394 |
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NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
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G |
Slc35g1 |
solute carrier family 35, member G1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC35G1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:236,163,593...236,172,115
Ensembl chr 1:236,163,175...236,170,262
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G |
Slc37a3 |
solute carrier family 37, member 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC37A3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:68,109,314...68,153,590
Ensembl chr 4:68,081,939...68,153,568
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G |
Slc38a1 |
solute carrier family 38, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC38A1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
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G |
Slc7a2 |
solute carrier family 7 member 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC7A2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
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G |
Slit1 |
slit guidance ligand 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SLIT1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
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G |
Smarca1 |
SNF2 related chromatin remodeling ATPase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SMARCA1 mRNA |
CTD |
PMID:34581912 |
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NCBI chr X:126,980,201...127,066,385
Ensembl chr X:126,994,947...127,066,347
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G |
Smoc1 |
SPARC related modular calcium binding 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SMOC1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699
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G |
Sms |
spermine synthase |
increases expression |
ISO |
T-2 Toxin results in increased expression of SMS mRNA |
CTD |
PMID:31863870 |
|
NCBI chr X:37,516,949...37,572,657
Ensembl chr X:37,516,931...37,570,822 Ensembl chr 3:37,516,931...37,570,822
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G |
Snrpf |
small nuclear ribonucleoprotein polypeptide F |
affects expression |
EXP |
T-2 Toxin affects the expression of SNRPF protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129
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G |
Snu13 |
small nuclear ribonucleoprotein 13 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SNU13 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872 Ensembl chr 1:113,565,295...113,570,872
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G |
Socs1 |
suppressor of cytokine signaling 1 |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of SOCS1 mRNA MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA] |
CTD |
PMID:32240701 |
|
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Sod1 |
superoxide dismutase 1 |
increases expression affects expression decreases activity decreases expression |
ISO EXP |
T-2 Toxin results in increased expression of SOD1 mRNA T-2 Toxin affects the expression of SOD1 protein T-2 Toxin results in decreased activity of SOD1 protein T-2 Toxin results in decreased expression of SOD1 mRNA |
CTD |
PMID:26138683 PMID:26141394 PMID:27842451 PMID:33508416 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
decreases expression increases expression |
EXP ISO |
T-2 Toxin results in decreased expression of SOD2 mRNA T-2 Toxin results in increased expression of SOD2 mRNA |
CTD |
PMID:26141394 PMID:29870751 PMID:30091165 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
ISO |
T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter] |
CTD |
PMID:31470059 |
|
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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