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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antihypotensive agent
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Accession:CHEBI:137431 term browser browse the term
Definition:A cardiovascular drug that tends to raise reduced blood pressure.
Synonyms:related_synonym: antihypotensive agents;   pressor;   pressors;   vasopressor agent;   vasopressor agents
 xref: Wikipedia:Antihypotensive_agent



show annotations for term's descendants           Sort by:
methoxamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1d adrenoceptor alpha 1D affects binding ISO Methoxamine binds to ADRA1D protein CTD PMID:15493479 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion
EXP Pregnanolone inhibits the reaction [Methoxamine results in increased secretion of CRH protein] CTD PMID:7816204 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Carbon Tetrachloride co-treated with Phenobarbital co-treated with Methoxamine] results in increased expression of PTGS2 protein CTD PMID:12500202 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tbxas1 thromboxane A synthase 1 multiple interactions EXP [Carbon Tetrachloride co-treated with Phenobarbital co-treated with Methoxamine] results in increased expression of TBXAS1 protein CTD PMID:12500202 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          drug 19532
            cardiovascular drug 8644
              antihypotensive agent 4
                2-phenylpropylamine + 0
                amezinium + 0
                amezinium metilsulfate 0
                methoxamine 4
paths to the root