|
G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
multiple interactions decreases activity |
ISO |
Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Atropine results in decreased activity of ABCB11 protein |
CTD |
PMID:24014644 |
|
NCBI chr 3:74,424,620...74,520,646
|
|
G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
[Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr 3:35,377,587...35,480,843
|
|
G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO EXP |
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein] [Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]] [1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein] |
CTD |
PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 PMID:21787676 PMID:22783142 PMID:23047022 PMID:24881594 PMID:26751814 PMID:31794810 More...
|
|
NCBI chr12:25,042,882...25,050,608
|
|
G |
Adcy5 |
adenylate cyclase 5 |
increases response to substance |
ISO |
ADCY5 protein results in increased susceptibility to Atropine |
CTD |
PMID:12869393 |
|
NCBI chr11:78,976,861...79,123,343
|
|
G |
Aqp5 |
aquaporin 5 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] |
CTD |
PMID:26208470 |
|
NCBI chr 7:130,722,675...130,726,207
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] |
CTD |
PMID:21971501 |
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bcar1 |
BCAR1 scaffold protein, Cas family member |
multiple interactions |
ISO |
Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] |
CTD |
PMID:10537051 |
|
NCBI chr19:39,679,215...39,713,907
|
|
G |
Bche |
butyrylcholinesterase |
multiple interactions |
EXP ISO |
[Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein [BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX |
CTD |
PMID:17963125 PMID:22981459 |
|
NCBI chr 2:160,607,289...160,699,760
|
|
G |
Bdkrb2 |
bradykinin receptor B2 |
multiple interactions |
ISO |
BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] |
CTD |
PMID:10614985 |
|
NCBI chr 6:130,237,055...130,267,205
|
|
G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions |
EXP |
Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] |
CTD |
PMID:18472332 |
|
NCBI chr17:26,523,704...26,785,558
|
|
G |
Cacna1e |
calcium voltage-gated channel subunit alpha1 E |
multiple interactions |
EXP |
Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] |
CTD |
PMID:12663092 |
|
NCBI chr13:66,574,659...67,063,443
|
|
G |
Calca |
calcitonin-related polypeptide alpha |
affects activity |
EXP |
Atropine affects the activity of CALCA protein |
CTD |
PMID:7906887 PMID:10075105 |
|
NCBI chr 1:178,312,636...178,317,588
|
|
G |
Casp3 |
caspase 3 |
increases expression |
EXP |
Atropine results in increased expression of CASP3 mRNA |
CTD |
PMID:19815060 |
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] |
CTD |
PMID:22245128 |
|
NCBI chr10:68,820,330...68,824,906
|
|
G |
Ccna1 |
cyclin A1 |
increases expression multiple interactions |
ISO |
Atropine results in increased expression of CCNA1 mRNA [Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr 2:141,383,352...141,428,205
|
|
G |
Ccnd3 |
cyclin D3 |
multiple interactions |
ISO |
[Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr 9:20,891,696...20,987,199
|
|
G |
Ccne1 |
cyclin E1 |
increases expression multiple interactions |
ISO |
Atropine results in increased expression of CCNE1 mRNA [Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr 1:99,918,672...99,927,986
|
|
G |
Ccne2 |
cyclin E2 |
multiple interactions increases expression |
ISO |
[Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA Atropine results in increased expression of CCNE2 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr 5:29,082,169...29,094,879
|
|
G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] |
CTD |
PMID:16879495 |
|
NCBI chr 3:174,209,113...174,224,592
|
|
G |
Cdc20 |
cell division cycle 20 |
multiple interactions increases expression |
ISO |
[Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA Atropine results in increased expression of CDC20 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr 5:137,251,596...137,255,799
|
|
G |
Cdc6 |
cell division cycle 6 |
multiple interactions |
ISO |
[Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr10:84,360,361...84,374,239
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions increases expression |
ISO |
[Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA Atropine results in increased expression of CDK1 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr20:19,265,252...19,280,456
|
|
G |
Ces1d |
carboxylesterase 1D |
multiple interactions |
ISO |
Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] |
CTD |
PMID:9311626 |
|
NCBI chr19:30,046,494...30,085,039
|
|
G |
Chrm1 |
cholinergic receptor, muscarinic 1 |
multiple interactions decreases activity |
ISO |
Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] Atropine results in decreased activity of CHRM1 protein Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein] |
CTD |
PMID:16439611 PMID:18316702 PMID:31830555 |
|
NCBI chr 1:205,567,226...205,583,001
|
|
G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
multiple interactions |
ISO |
Atropine binds to and results in decreased activity of CHRM2 protein |
CTD |
PMID:15140916 |
|
NCBI chr 4:65,981,136...66,116,128
|
|
G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
multiple interactions decreases activity |
ISO |
Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein] Atropine results in decreased activity of CHRM3 protein |
CTD |
PMID:15140916 PMID:20708676 PMID:31830555 |
|
NCBI chr17:64,696,549...65,158,622
|
|
G |
Chrm4 |
cholinergic receptor, muscarinic 4 |
multiple interactions affects binding |
ISO |
[WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] |
CTD |
PMID:16709648 |
|
NCBI chr 3:98,349,080...98,356,821
|
|
G |
Chrm5 |
cholinergic receptor, muscarinic 5 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] |
CTD |
PMID:31323226 |
|
NCBI chr 3:99,284,846...99,337,252
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions affects binding |
ISO EXP |
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]] Atropine binds to [CHRNA4 protein binds to CHRNB2 protein] |
CTD |
PMID:15733544 PMID:21791372 |
|
NCBI chr 3:168,136,246...168,157,839
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
affects binding multiple interactions |
ISO EXP |
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein] Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]] Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:15733544 PMID:21791372 |
|
NCBI chr 2:175,181,402...175,189,619
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] |
CTD |
PMID:21971501 |
|
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Crh |
corticotropin releasing hormone |
multiple interactions |
EXP ISO |
Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein] [Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein |
CTD |
PMID:12039681 PMID:12906840 |
|
NCBI chr 2:104,059,184...104,061,048
|
|
G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] |
CTD |
PMID:17390078 |
|
NCBI chr 8:129,517,576...129,544,661
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] |
CTD |
PMID:22245128 |
|
NCBI chr14:17,571,900...17,573,624
|
|
G |
Dvl2 |
dishevelled segment polarity protein 2 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] |
CTD |
PMID:17390078 |
|
NCBI chr10:54,723,356...54,732,823
|
|
G |
Edn1 |
endothelin 1 |
multiple interactions |
ISO |
EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] |
CTD |
PMID:12906840 |
|
NCBI chr17:22,660,799...22,666,687
|
|
G |
Eef2 |
eukaryotic translation elongation factor 2 |
multiple interactions |
ISO |
atropine inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] |
RGD |
PMID:31227218 |
RGD:153298919 |
NCBI chr 7:9,183,836...9,196,255
|
|
G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] |
CTD |
PMID:17390078 |
|
NCBI chr14:95,378,626...95,551,358
|
|
G |
Egr1 |
early growth response 1 |
multiple interactions |
EXP |
Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] |
CTD |
PMID:7968354 |
|
NCBI chr18:26,737,078...26,740,877
|
|
G |
Egr2 |
early growth response 2 |
multiple interactions |
EXP |
Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] |
CTD |
PMID:7968354 |
|
NCBI chr20:21,051,270...21,056,322
|
|
G |
Ezr |
ezrin |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] |
CTD |
PMID:17390078 |
|
NCBI chr 1:49,373,033...49,416,573
|
|
G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
ISO |
[Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein |
CTD |
PMID:30515700 |
|
NCBI chr 3:98,051,958...98,065,246
|
|
G |
F2r |
coagulation factor II (thrombin) receptor |
multiple interactions |
ISO |
[Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein |
CTD |
PMID:30515700 |
|
NCBI chr 2:26,869,343...26,885,856
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP ISO |
Atropine results in increased expression of FOS protein Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA] [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA] |
CTD |
PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 |
|
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Ghrl |
ghrelin and obestatin prepropeptide |
multiple interactions |
EXP |
Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] |
CTD |
PMID:16959836 |
|
NCBI chr 4:146,865,712...146,869,621
|
|
G |
Glra1 |
glycine receptor, alpha 1 |
multiple interactions |
ISO |
Atropine binds to and results in decreased activity of GLRA1 protein |
CTD |
PMID:15081878 |
|
NCBI chr10:40,128,284...40,228,612
|
|
G |
Grm4 |
glutamate metabotropic receptor 4 |
multiple interactions |
ISO |
Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] |
CTD |
PMID:18171729 |
|
NCBI chr20:5,484,172...5,572,821
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] |
CTD |
PMID:22245128 |
|
NCBI chr 8:27,829,688...27,841,618
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] |
CTD |
PMID:22245128 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] |
CTD |
PMID:22245128 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] |
CTD |
PMID:21971501 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] |
CTD |
PMID:7968354 |
|
NCBI chr19:23,176,265...23,178,049
|
|
G |
Kcnj3 |
potassium inwardly-rectifying channel, subfamily J, member 3 |
multiple interactions |
ISO |
Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] |
CTD |
PMID:18171729 |
|
NCBI chr 3:39,944,896...40,106,646
|
|
G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] |
CTD |
PMID:17390078 |
|
NCBI chr14:32,901,615...32,978,895
|
|
G |
Ltf |
lactotransferrin |
multiple interactions |
ISO |
Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] |
CTD |
PMID:11112886 |
|
NCBI chr 8:110,999,948...111,022,795
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:21971501 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:21971501 |
|
NCBI chr20:6,751,288...6,812,294
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:21971501 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:21971501 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mcm4 |
minichromosome maintenance complex component 4 |
multiple interactions increases expression |
ISO |
[Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA Atropine results in increased expression of MCM4 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr11:98,762,599...98,776,300
|
|
G |
Mcm6 |
minichromosome maintenance complex component 6 |
increases expression multiple interactions |
ISO |
Atropine results in increased expression of MCM6 mRNA [Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA |
CTD |
PMID:17390078 |
|
NCBI chr13:42,379,161...42,404,352
|
|
G |
Nefh |
neurofilament heavy chain |
affects expression |
EXP |
Atropine affects the expression of NEFH mRNA |
CTD |
PMID:22954530 |
|
NCBI chr14:84,044,428...84,054,413
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression |
ISO |
Atropine results in increased expression of NLRP3 mRNA |
CTD |
PMID:28138970 |
|
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] |
CTD |
PMID:15610444 PMID:16944022 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Notch4 |
notch receptor 4 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] |
CTD |
PMID:17390078 |
|
NCBI chr20:4,160,362...4,184,466
|
|
G |
Nppa |
natriuretic peptide A |
affects activity |
EXP |
Atropine affects the activity of NPPA protein modified form |
CTD |
PMID:1363893 |
|
NCBI chr 5:163,712,184...163,713,493
|
|
G |
Oprl1 |
opioid related nociceptin receptor 1 |
multiple interactions |
EXP |
Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] |
CTD |
PMID:12007927 |
|
NCBI chr 3:189,209,495...189,225,406
|
|
G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] |
CTD |
PMID:12762645 |
|
NCBI chr 3:139,951,948...139,955,820
|
|
G |
Pnoc |
prepronociceptin |
multiple interactions |
EXP |
Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] |
CTD |
PMID:12007927 |
|
NCBI chr15:43,800,240...43,827,841
|
|
G |
Pomc |
proopiomelanocortin |
multiple interactions |
EXP |
Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] |
CTD |
PMID:7588217 |
|
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
[Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] |
CTD |
PMID:18812576 |
|
NCBI chr 7:118,712,261...118,780,723
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] |
CTD |
PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Ptk2 |
protein tyrosine kinase 2 |
multiple interactions |
ISO |
Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] |
CTD |
PMID:10537051 |
|
NCBI chr 7:107,015,730...107,220,865
|
|
G |
Pxn |
paxillin |
multiple interactions |
ISO |
Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] |
CTD |
PMID:10537051 |
|
NCBI chr12:41,060,791...41,107,952
|
|
G |
Rac3 |
Rac family small GTPase 3 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] |
CTD |
PMID:17390078 |
|
NCBI chr10:106,002,808...106,005,243
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] |
CTD |
PMID:21971501 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Rhoa |
ras homolog family member A |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] |
CTD |
PMID:17390078 |
|
NCBI chr 8:117,870,548...117,904,303
|
|
G |
Slc22a1 |
solute carrier family 22 member 1 |
multiple interactions |
ISO |
Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:16263091 PMID:21641380 |
|
NCBI chr 1:50,624,339...50,651,437
|
|
G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] |
CTD |
PMID:16263091 PMID:21599003 PMID:23770354 |
|
NCBI chr 1:50,668,817...50,711,019
|
|
G |
Slc22a3 |
solute carrier family 22 member 3 |
increases uptake multiple interactions |
ISO |
SLC22A3 protein results in increased uptake of Atropine Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:16263091 |
|
NCBI chr 1:50,783,218...50,872,358
|
|
G |
Slc22a4 |
solute carrier family 22 member 4 |
multiple interactions |
ISO |
Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] |
CTD |
PMID:21641380 |
|
NCBI chr10:38,133,333...38,179,932
|
|
G |
Slc47a1 |
solute carrier family 47 member 1 |
multiple interactions |
ISO |
Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
|
NCBI chr10:46,533,580...46,590,128
|
|
G |
Slc47a2 |
solute carrier family 47 member 2 |
multiple interactions |
ISO |
Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
|
NCBI chr10:46,490,262...46,532,954
|
|
G |
Slpi |
secretory leukocyte peptidase inhibitor |
increases expression |
ISO |
Atropine results in increased expression of SLPI mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 3:173,501,573...173,503,822
|
|
G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] |
CTD |
PMID:22245128 |
|
NCBI chr10:103,692,579...103,695,975
|
|
G |
Spn |
sialophorin |
increases response to substance |
ISO |
SPN protein results in increased susceptibility to Atropine |
CTD |
PMID:18711009 |
|
NCBI chr 1:181,746,937...181,759,564
|
|
G |
Tat |
tyrosine aminotransferase |
multiple interactions |
EXP |
[Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] |
CTD |
PMID:7761789 |
|
NCBI chr19:37,947,153...37,957,717
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] |
CTD |
PMID:18472332 |
|
NCBI chr 1:90,324,312...90,340,627
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] |
CTD |
PMID:22245128 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] |
CTD |
PMID:12762645 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Trio |
trio Rho guanine nucleotide exchange factor |
multiple interactions |
ISO |
Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] |
CTD |
PMID:17390078 |
|
NCBI chr 2:80,235,485...80,531,824
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
decreases response to substance |
ISO |
TRPA1 gene mutant form results in decreased susceptibility to Atropine |
CTD |
PMID:29627347 |
|
NCBI chr 5:9,163,060...9,217,325
|
|
G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions |
EXP |
[pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] |
CTD |
PMID:15891268 |
|
NCBI chr 2:190,224,676...190,229,559
|
|
G |
Tspo |
translocator protein |
multiple interactions |
EXP |
[Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein |
CTD |
PMID:33823148 |
|
NCBI chr 7:116,600,214...116,610,461
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] |
CTD |
PMID:22245128 |
|
NCBI chr 2:206,723,050...206,742,783
|
|
|
G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
decreases activity |
ISO |
Biperiden results in decreased activity of ABCB4 protein |
CTD |
PMID:28437613 |
|
NCBI chr 4:26,106,895...26,164,440
|
|
G |
Bmp6 |
bone morphogenetic protein 6 |
increases expression |
ISO |
Biperiden results in increased expression of BMP6 mRNA |
CTD |
PMID:32816093 |
|
NCBI chr17:26,523,704...26,785,558
|
|
G |
Chrm1 |
cholinergic receptor, muscarinic 1 |
multiple interactions |
EXP |
Biperiden binds to and results in decreased activity of CHRM1 protein |
CTD |
PMID:21336581 |
|
NCBI chr 1:205,567,226...205,583,001
|
|
G |
Ereg |
epiregulin |
increases expression |
ISO |
Biperiden results in increased expression of EREG mRNA |
CTD |
PMID:32816093 |
|
NCBI chr14:17,311,485...17,325,260
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression |
ISO |
Biperiden results in increased expression of IL1A mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Il1b |
interleukin 1 beta |
increases expression |
ISO |
Biperiden results in increased expression of IL1B mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il24 |
interleukin 24 |
increases expression |
ISO |
Biperiden results in increased expression of IL24 mRNA |
CTD |
PMID:32816093 |
|
NCBI chr13:44,905,362...44,910,760
|
|
G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
increases expression |
ISO |
Biperiden results in increased expression of MET mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 4:46,756,823...46,864,041
|
|
G |
Pid1 |
phosphotyrosine interaction domain containing 1 |
increases expression |
ISO |
Biperiden results in increased expression of PID1 mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 9:85,284,335...85,503,035
|
|
G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Biperiden results in increased expression of SLC7A11 mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 2:136,532,912...136,668,560
|
|
|
G |
Ache |
acetylcholinesterase |
affects binding multiple interactions |
ISO EXP |
pralidoxime binds to ACHE protein pralidoxime binds to and results in decreased activity of ACHE protein; pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein] [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX analog results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]] pralidoxime inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Cholinesterase Inhibitors binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [cyclohexyl methylphosphonofluoridate binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [cyclohexyl methylphosphonofluoridate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Diazinon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [dicrotophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dimethoate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [dimethoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [ethylparaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [heptenophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [leptophos oxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methamidophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methyl demeton results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Mevinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Obidoxime Chloride results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Organophosphates binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein mutant form]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Soman results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein mutant form]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [VX results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [Carbaryl results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [Propoxur results in decreased activity of ACHE protein] |
CTD |
PMID:1494302 PMID:8134223 PMID:8783813 PMID:15669039 PMID:16025528 PMID:16112538 PMID:16598855 PMID:17265452 PMID:17963125 PMID:18070496 PMID:18344198 PMID:18804659 PMID:19917271 PMID:20096273 PMID:20156430 PMID:20227398 PMID:20382137 PMID:20406208 PMID:20412789 PMID:20433814 PMID:20688148 PMID:20971170 PMID:21673941 PMID:21723318 PMID:21983245 PMID:22783142 PMID:22960624 PMID:22975155 PMID:23073172 PMID:23111374 PMID:23123249 PMID:23962483 PMID:25451328 PMID:25743373 PMID:26070418 PMID:26210933 PMID:26368669 PMID:26751814 PMID:27129421 PMID:27138243 PMID:27551891 PMID:29614332 PMID:29772260 PMID:29920286 PMID:31276662 More...
|
|
NCBI chr12:25,042,882...25,050,608
|
|
G |
Bche |
butyrylcholinesterase |
multiple interactions affects binding |
ISO EXP |
pralidoxime binds to and results in decreased activity of BCHE protein [Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of BCHE protein; pralidoxime affects the reaction [4-nitrophenyl 2-propylmethylphosphonate results in decreased activity of BCHE protein]; pralidoxime affects the reaction [ethyl 4-nitrophenyl methylphosphonate results in decreased activity of BCHE protein] BCHE protein binds to pralidoxime pralidoxime binds to and affects the activity of BCHE protein; pralidoxime inhibits the reaction [Chlorpyrifos results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Cholinesterase Inhibitors binds to and results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Isoflurophate inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Organophosphates binds to and results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [quinalphos results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [VX analog results in decreased activity of BCHE protein] |
CTD |
PMID:423703 PMID:16598855 PMID:17963125 PMID:18825528 PMID:20227398 PMID:21802514 PMID:22922115 PMID:24052565 PMID:26705700 PMID:27551891 PMID:29614332 PMID:29920286 PMID:31173753 PMID:32278739 More...
|
|
NCBI chr 2:160,607,289...160,699,760
|
|
G |
Cat |
catalase |
multiple interactions |
ISO |
[Malathion co-treated with pralidoxime] results in increased activity of CAT protein |
CTD |
PMID:21723318 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Pon1 |
paraoxonase 1 |
multiple interactions |
EXP |
pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein] |
CTD |
PMID:29098328 |
|
NCBI chr 4:34,261,312...34,292,327
|
|
G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
pralidoxime inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
|
|
G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions |
EXP |
[pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] |
CTD |
PMID:15891268 |
|
NCBI chr 2:190,224,676...190,229,559
|
|