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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antidote to sarin poisoning
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Accession:CHEBI:136860 term browser browse the term
Definition:A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions
decreases activity
ISO Atropine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Atropine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of ABL1 mRNA CTD PMID:17390078 NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
Atropine inhibits the reaction [[Organophosphorus Compounds results in decreased activity of ACHE protein] which results in increased abundance of Acetylcholine]; Atropine inhibits the reaction [Carbachol results in increased metabolism of and results in increased secretion of ACHE protein]; Atropine inhibits the reaction [Paraoxon results in increased expression of ACHE protein]
[Atropine co-treated with Obidoxime Chloride] inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [tariquidar co-treated with asoxime chloride co-treated with Atropine] inhibits the reaction [Soman results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Atropine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein]
CTD PMID:2241428 PMID:10421444 PMID:17963125 PMID:20105433 PMID:21600273 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance EXP ADCY5 protein results in increased susceptibility to Atropine CTD PMID:12869393 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
JBrowse link
G Aqp5 aquaporin 5 multiple interactions EXP Atropine inhibits the reaction [Pilocarpine affects the localization of AQP5 protein] CTD PMID:26208470 NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the expression of BAX mRNA] CTD PMID:21971501 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] CTD PMID:10537051 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein
[BCHE protein co-treated with asoxime chloride co-treated with pro-diazepam co-treated with Atropine] results in decreased susceptibility to VX
CTD PMID:17963125 PMID:22981459 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions EXP BDKRB2 affects the susceptibility to [Propranolol co-treated with Atropine] CTD PMID:10614985 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of BMP6 mRNA] CTD PMID:18472332 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit multiple interactions ISO Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]] CTD PMID:12663092 NCBI chr 1:154,266,552...154,760,374
Ensembl chr 1:154,266,477...154,760,247
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha affects activity ISO Atropine affects the activity of CALCA protein CTD PMID:7906887 PMID:10075105 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Casp3 caspase 3 increases expression ISO Atropine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein] CTD PMID:22245128 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccna1 cyclin A1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNA1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNA1 mRNA
CTD PMID:17390078 NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CCND3 mRNA CTD PMID:17390078 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions
ISO Atropine results in increased expression of CCNE1 mRNA
[Parathion co-treated with Atropine] results in increased expression of CCNE1 mRNA
CTD PMID:17390078 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Ccne2 cyclin E2 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CCNE2 mRNA
Atropine results in increased expression of CCNE2 mRNA
CTD PMID:17390078 NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
JBrowse link
G Cd40 CD40 antigen multiple interactions ISO Atropine inhibits the reaction [Carbachol results in increased expression of CD40 protein] CTD PMID:16879495 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDC20 mRNA
Atropine results in increased expression of CDC20 mRNA
CTD PMID:17390078 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Parathion co-treated with Atropine] results in increased expression of CDC6 mRNA CTD PMID:17390078 NCBI chr11:98,798,627...98,814,768
Ensembl chr11:98,798,627...98,814,766
JBrowse link
G Cdk1 cyclin dependent kinase 1 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of CDK1 mRNA
Atropine results in increased expression of CDK1 mRNA
CTD PMID:17390078 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions
decreases activity
EXP
ISO
Atropine binds to and results in decreased activity of CHRM1 protein; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
Atropine results in decreased activity of CHRM1 protein
Atropine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]
CTD PMID:16439611 PMID:18316702 PMID:31830555 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Atropine binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac multiple interactions
decreases activity
ISO Atropine binds to and results in decreased activity of CHRM3 protein; Atropine inhibits the reaction [Carbachol results in increased activity of CHRM3 protein]
Atropine results in decreased activity of CHRM3 protein
CTD PMID:15140916 PMID:20708676 PMID:31830555 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding
ISO [WIN 62577 co-treated with Quinuclidinyl Benzilate] inhibits the reaction [Atropine binds to CHRM4 protein] CTD PMID:16709648 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased activity of CHRM5 protein] CTD PMID:31323226 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114
JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions
affects binding
ISO Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNA4 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit affects binding
multiple interactions
ISO Atropine binds to [CHRNA4 protein binds to CHRNB2 protein]
Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 mRNA]]; Atropine promotes the reaction [Mecamylamine inhibits the reaction [Paraoxon results in decreased expression of CHRNB2 protein]]
Atropine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:15733544 PMID:21791372 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of CREB1 protein] CTD PMID:21971501 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; Atropine inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; Atropine inhibits the reaction [methamidophos results in increased secretion of CRH protein]
[Atropine co-treated with SR 140333 co-treated with SR 48968] results in decreased activity of CRH protein
CTD PMID:12039681 PMID:12906840 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein mutant form]; Atropine inhibits the reaction [Parathion results in increased expression of CTNNB1 protein] CTD PMID:17390078 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein] CTD PMID:22245128 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of DVL2 protein] CTD PMID:17390078 NCBI chr11:69,891,418...69,900,935
Ensembl chr11:69,891,421...69,903,127
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions ISO atropine inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] RGD PMID:31227218 RGD:153298919 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR1 mRNA] CTD PMID:7968354 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of EGR2 mRNA] CTD PMID:7968354 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Ezr ezrin multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of EZR protein] CTD PMID:17390078 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G F2 coagulation factor II multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 protein CTD PMID:30515700 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2r coagulation factor II thrombin receptor multiple interactions EXP [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased expression of F2R protein CTD PMID:30515700 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression
multiple interactions
ISO Atropine results in increased expression of FOS protein
[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased expression of FOS protein]; Atropine inhibits the reaction [Pilocarpine results in increased expression of FOS mRNA]
Atropine inhibits the reaction [Paraoxon results in increased expression of FOS mRNA]
CTD PMID:7968354 PMID:8281324 PMID:21787676 PMID:21971501 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Ghrl ghrelin multiple interactions ISO Atropine inhibits the reaction [[Pentobarbital co-treated with L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide] results in increased expression of GHRL protein] CTD PMID:16959836 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841
JBrowse link
G Glra1 glycine receptor, alpha 1 subunit multiple interactions ISO Atropine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr11:55,405,065...55,499,024
Ensembl chr11:55,405,064...55,499,024
JBrowse link
G Grm4 glutamate receptor, metabotropic 4 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr17:27,641,361...27,732,800
Ensembl chr17:27,641,361...27,740,377
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein] CTD PMID:22245128 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein] CTD PMID:22245128 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein] CTD PMID:22245128 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of JUN protein] CTD PMID:21971501 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene multiple interactions ISO Atropine inhibits the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7968354 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Atropine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] CTD PMID:18171729 NCBI chr 2:55,301,814...55,488,157
Ensembl chr 2:55,325,982...55,488,157
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of KIT protein] CTD PMID:17390078 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ltf lactotransferrin multiple interactions ISO Atropine inhibits the reaction [methylcholine results in increased secretion of LTF protein] CTD PMID:11112886 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK1 protein] CTD PMID:21971501 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein] CTD PMID:21971501 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK3 protein] CTD PMID:21971501 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions
increases expression
ISO [Parathion co-treated with Atropine] results in increased expression of MCM4 mRNA
Atropine results in increased expression of MCM4 mRNA
CTD PMID:17390078 NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression
multiple interactions
ISO Atropine results in increased expression of MCM6 mRNA
[Parathion co-treated with Atropine] results in increased expression of MCM6 mRNA
CTD PMID:17390078 NCBI chr 1:128,259,312...128,287,442
Ensembl chr 1:128,259,327...128,287,401
JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Atropine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Atropine results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Atropine inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Atropine inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:15610444 PMID:16944022 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch4 notch 4 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of NOTCH4 protein] CTD PMID:17390078 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477
JBrowse link
G Nppa natriuretic peptide type A affects activity ISO Atropine affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Oprl1 opioid receptor-like 1 multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA]; Atropine inhibits the reaction [Parathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pnoc prepronociceptin multiple interactions ISO Atropine inhibits the reaction [PNOC protein binds to and results in increased activity of OPRL1 protein] CTD PMID:12007927 NCBI chr14:65,638,931...65,662,908
Ensembl chr14:65,638,122...65,662,921
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions ISO Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] CTD PMID:7588217 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP [Atropine co-treated with Glucose] binds to PPARA protein; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Atropine affects the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]; Atropine inhibits the reaction [Indomethacin results in increased expression of PTGS2]; Atropine inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15104355 PMID:15610444 PMID:16259740 PMID:16804302 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] CTD PMID:10537051 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129
JBrowse link
G Pxn paxillin multiple interactions ISO Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 NCBI chr 5:115,630,035...115,694,046
Ensembl chr 5:115,644,735...115,694,046
JBrowse link
G Rac3 Rac family small GTPase 3 multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RAC3 protein] CTD PMID:17390078 NCBI chr11:120,612,294...120,614,795
Ensembl chr11:120,612,296...120,614,795
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman affects the phosphorylation of RELA protein] CTD PMID:21971501 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein] CTD PMID:17390078 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions ISO Atropine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 PMID:21641380 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Atropine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Atropine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:16263091 PMID:21599003 PMID:23770354 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 increases uptake
multiple interactions
ISO SLC22A3 protein results in increased uptake of Atropine
Atropine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]
CTD PMID:16263091 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591
JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 multiple interactions ISO Atropine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916
JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Atropine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Atropine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Atropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA] CTD PMID:22245128 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Spn sialophorin increases response to substance EXP SPN protein results in increased susceptibility to Atropine CTD PMID:18711009 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995
JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Atropine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:18472332 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein] CTD PMID:22245128 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trio triple functional domain (PTPRF interacting) multiple interactions ISO Atropine inhibits the reaction [Parathion results in increased expression of TRIO protein] CTD PMID:17390078 NCBI chr15:27,730,735...28,025,954
Ensembl chr15:27,730,737...28,025,934
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]; Atropine inhibits the reaction [Parathion results in increased expression of TP53 protein] CTD PMID:12762645 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases response to substance EXP TRPA1 gene mutant form results in decreased susceptibility to Atropine CTD PMID:29627347 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions ISO [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
JBrowse link
G Tspo translocator protein multiple interactions ISO [Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein CTD PMID:33823148 NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA] CTD PMID:22245128 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
biperiden term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases activity ISO Biperiden results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Biperiden results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions ISO Biperiden binds to and results in decreased activity of CHRM1 protein CTD PMID:21336581 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO Biperiden results in increased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Ereg epiregulin increases expression ISO Biperiden results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Biperiden results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Biperiden results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il24 interleukin 24 increases expression ISO Biperiden results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Met met proto-oncogene increases expression ISO Biperiden results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Biperiden results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Biperiden results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
pralidoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
affects binding
EXP
ISO
pralidoxime binds to and results in decreased activity of ACHE protein; pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein]
pralidoxime binds to ACHE protein
[Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of ACHE protein; [Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [[Paraoxon co-treated with pralidoxime co-treated with Atropine] results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX analog results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]
pralidoxime inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Cholinesterase Inhibitors binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [cyclohexyl methylphosphonofluoridate binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [cyclohexyl methylphosphonofluoridate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Diazinon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [dicrotophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dimethoate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [dimethoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [ethylparaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [heptenophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [leptophos oxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methamidophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methyl demeton results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [methylparaoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Mevinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Obidoxime Chloride results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Organophosphates binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein mutant form]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Soman results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein mutant form]; pralidoxime inhibits the reaction [tabun results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [VX results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [VX results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [Carbaryl results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [Propoxur results in decreased activity of ACHE protein]
CTD PMID:1494302 PMID:8134223 PMID:8783813 PMID:15669039 PMID:16025528 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Bche butyrylcholinesterase multiple interactions
affects binding
EXP
ISO
pralidoxime binds to and results in decreased activity of BCHE protein
[Atropine co-treated with pralidoxime] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of BCHE protein; pralidoxime affects the reaction [4-nitrophenyl 2-propylmethylphosphonate results in decreased activity of BCHE protein]; pralidoxime affects the reaction [ethyl 4-nitrophenyl methylphosphonate results in decreased activity of BCHE protein]
BCHE protein binds to pralidoxime
pralidoxime binds to and affects the activity of BCHE protein; pralidoxime inhibits the reaction [Chlorpyrifos results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Cholinesterase Inhibitors binds to and results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Isoflurophate inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Organophosphates binds to and results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [quinalphos results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [VX analog results in decreased activity of BCHE protein]
CTD PMID:423703 PMID:16598855 PMID:17963125 PMID:18825528 PMID:20227398 More... NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Cat catalase multiple interactions EXP [Malathion co-treated with pralidoxime] results in increased activity of CAT protein CTD PMID:21723318 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein] CTD PMID:29098328 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO pralidoxime inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions ISO [pralidoxime co-treated with Atropine] inhibits the reaction [methamidophos results in decreased expression of TSHB protein] CTD PMID:15891268 NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
JBrowse link

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  CHEBI ontology 22317
    role 22303
      application 21914
        pharmaceutical 21272
          drug 21272
            protective agent 18677
              antidote 9576
                antidote to sarin poisoning 105
                  atropine + 95
                  biperiden + 11
                  pralidoxime + 6
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