|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP ISO |
cilnidipine inhibits the reaction [Iohexol results in increased expression of BAX protein] |
CTD |
PMID:36207783 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO EXP |
cilnidipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein] |
CTD |
PMID:36207783 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Camk2g |
calcium/calmodulin-dependent protein kinase II gamma |
multiple interactions |
ISO |
cilnidipine inhibits the reaction [CAMK2G protein promotes the reaction [Iohexol results in increased cleavage of CASP3 protein]] |
CTD |
PMID:36207783 |
|
NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
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|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO EXP |
cilnidipine inhibits the reaction [CAMK2G protein promotes the reaction [Iohexol results in increased cleavage of CASP3 protein]]; cilnidipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein] |
CTD |
PMID:36207783 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
decreases activity |
ISO |
cilnidipine results in decreased activity of CYP2J2 protein |
CTD |
PMID:30965050 |
|
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Esr1 |
estrogen receptor 1 |
decreases activity |
ISO |
cilnidipine results in decreased activity of ESR1 protein |
CTD |
PMID:25257666 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Fgf2 |
fibroblast growth factor 2 |
decreases expression |
EXP |
cilnidipine results in decreased expression of FGF2 mRNA |
CTD |
PMID:16333380 |
|
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
cilnidipine inhibits the reaction [Iohexol results in increased expression of HAVCR1 protein] |
CTD |
PMID:36207783 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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|
G |
Lcn2 |
lipocalin 2 |
multiple interactions |
EXP |
cilnidipine inhibits the reaction [Iohexol results in increased expression of LCN2 protein] |
CTD |
PMID:36207783 |
|
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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|
G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
cilnidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions increases activity |
ISO |
cilnidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]; cilnidipine inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; cilnidipine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] cilnidipine results in increased activity of NR1H4 protein |
CTD |
PMID:25257666 PMID:27773686 |
|
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
decreases activity |
ISO |
cilnidipine results in decreased activity of PPARD protein |
CTD |
PMID:25257666 |
|
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases activity |
ISO |
cilnidipine results in decreased activity of PPARG protein |
CTD |
PMID:25257666 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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|
G |
Ppif |
peptidylprolyl isomerase F |
multiple interactions |
EXP ISO |
cilnidipine inhibits the reaction [Iohexol results in increased expression of PPIF protein] |
CTD |
PMID:36207783 |
|
NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
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G |
Tgfb1 |
transforming growth factor, beta 1 |
decreases expression |
EXP |
cilnidipine results in decreased expression of TGFB1 mRNA |
CTD |
PMID:16333380 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Ano1 |
anoctamin 1 |
decreases activity |
ISO |
Nimodipine results in decreased activity of ANO1 protein |
CTD |
PMID:33872679 |
|
NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
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G |
App |
amyloid beta precursor protein |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium] |
CTD |
PMID:12383957 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Ar |
androgen receptor |
decreases activity |
ISO |
Nimodipine results in decreased activity of AR protein |
CTD |
PMID:25257666 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
Nimodipine results in increased expression of BAX protein Nimodipine inhibits the reaction [Sevoflurane results in increased expression of BAX protein] |
CTD |
PMID:17490525 PMID:33171207 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO EXP |
Nimodipine results in decreased expression of BCL2 protein Nimodipine inhibits the reaction [Sevoflurane results in decreased expression of BCL2 protein] |
CTD |
PMID:17490525 PMID:33171207 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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|
G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased expression of BDNF protein] |
CTD |
PMID:30776390 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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|
G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Dibutyl Phthalate results in decreased expression of BIRC5 protein] |
CTD |
PMID:33336902 |
|
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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|
G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein] |
CTD |
PMID:27095094 |
|
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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|
G |
Calca |
calcitonin-related polypeptide alpha |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Potassium results in increased secretion of CALCA protein] |
CTD |
PMID:18178321 |
|
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity |
ISO EXP |
Palmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP3 protein] [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; Nimodipine inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein] Nimodipine inhibits the reaction [Sevoflurane results in increased expression of CASP3 protein modified form] |
CTD |
PMID:22700542 PMID:30776390 PMID:33171207 PMID:33336902 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Casp7 |
caspase 7 |
multiple interactions increases activity |
ISO |
Palmitic Acid promotes the reaction [Nimodipine results in increased activity of CASP7 protein] |
CTD |
PMID:22700542 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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|
G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Sevoflurane results in increased expression of CASP9 protein modified form] |
CTD |
PMID:33171207 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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|
G |
Cat |
catalase |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Pilocarpine results in increased expression of CAT protein] |
CTD |
PMID:16115668 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions increases activity |
ISO |
3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Nimodipine results in increased activity of CFTR protein]; Colforsin promotes the reaction [Nimodipine results in increased activity of CFTR protein] |
CTD |
PMID:33872679 |
|
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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|
G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [cypermethrin results in increased expression of CGA mRNA] |
CTD |
PMID:28731686 |
|
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Clu |
clusterin |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Cadmium results in increased expression of CLU protein]; Nimodipine inhibits the reaction [Zinc results in increased expression of CLU protein] |
CTD |
PMID:19288494 |
|
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein] |
CTD |
PMID:27095094 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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|
G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of CREB1 protein]; Nimodipine inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of CREB1 protein] |
CTD |
PMID:30776390 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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|
G |
Cycs |
cytochrome c, somatic |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Sevoflurane results in increased expression of CYCS protein] |
CTD |
PMID:33171207 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [cypermethrin results in increased expression of CYP11A1 mRNA] |
CTD |
PMID:28731686 PMID:35931855 |
|
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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|
G |
Dbh |
dopamine beta-hydroxylase |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of DBH protein] |
CTD |
PMID:12186780 |
|
NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
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|
G |
Drd2 |
dopamine receptor D2 |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Dichlorvos results in decreased activity of DRD2 protein] |
CTD |
PMID:12186780 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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|
G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Zinc results in increased expression of EGR1 protein] |
CTD |
PMID:10428039 |
|
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP ISO |
Nimodipine affects the reaction [Haloperidol results in increased expression of FOS protein] Nimodipine results in increased expression of FOS mRNA |
CTD |
PMID:12730611 PMID:17913375 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [cypermethrin results in increased expression of FSHB mRNA]; Nimodipine inhibits the reaction [cypermethrin results in increased secretion of FSHB protein] |
CTD |
PMID:28731686 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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|
G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein] |
CTD |
PMID:27095094 |
|
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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|
G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of GJA1 protein] |
CTD |
PMID:36925031 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions |
ISO |
Nimodipine promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA] |
CTD |
PMID:27095094 |
|
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [4-OH-2',3,3',4',5'-pentachlorobiphenyl results in increased expression of JUN protein] |
CTD |
PMID:16300829 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] |
CTD |
PMID:11040061 |
|
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [cypermethrin results in increased expression of LHB mRNA]; Nimodipine inhibits the reaction [cypermethrin results in increased secretion of LHB protein] |
CTD |
PMID:28731686 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Map2 |
microtubule-associated protein 2 |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Dichlorvos results in increased phosphorylation of MAP2 protein] |
CTD |
PMID:16635102 |
|
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK1 protein]; Nimodipine inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nimodipine inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:29149324 PMID:30776390 PMID:33336902 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK3 protein]; Nimodipine inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nimodipine inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:29149324 PMID:30776390 PMID:33336902 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
EXP |
Nimodipine promotes the reaction [ferrous sulfate results in increased expression of MMP13 protein] |
CTD |
PMID:27095094 |
|
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Nppc |
natriuretic peptide C |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium] |
CTD |
PMID:18222015 |
|
NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions decreases activity increases activity |
ISO |
Nimodipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]; Nimodipine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] Nimodipine results in decreased activity of NR1H4 protein Nimodipine results in increased activity of NR1H4 protein |
CTD |
PMID:25257666 PMID:27773686 |
|
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity |
ISO |
Nimodipine results in increased activity of NR1I2 protein |
CTD |
PMID:21068194 PMID:25455453 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Prkca |
protein kinase C, alpha |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of PRKCA protein] |
CTD |
PMID:36925031 |
|
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of RAF1 protein] |
CTD |
PMID:29149324 |
|
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Slc11a2 |
solute carrier family 11 member 2 |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of SLC11A2 protein] |
CTD |
PMID:27095094 |
|
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
Nimodipine inhibits the reaction [cypermethrin results in increased expression of STAR mRNA] |
CTD |
PMID:28731686 PMID:35931855 |
|
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein] |
CTD |
PMID:12186780 |
|
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
EXP |
Nimodipine inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein] |
CTD |
PMID:27095094 |
|
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein] |
CTD |
PMID:30776390 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
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