propesticide - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	propesticide	go back to main search page
Accession:	CHEBI:136643	browse the term
Definition:	A prodrug that, on administration, undergoes chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active pesticide for which it is a propesticide.
Synonyms:	related_synonym:	pro-pesticide; pro-pesticides; propesticides
	xref:	AGR:IND84086009; PMID:26449612

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Genes (1373)

aldrin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate aminotransferase

increases expression

Aldrin results in increased expression of AADAT mRNA

NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332

G

ATP binding cassette subfamily D member 3

increases expression

Aldrin results in increased expression of ABCD3 mRNA

NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

decreases expression

Aldrin results in decreased expression of ACAP3 mRNA

NCBI chr 5:166,501,150...166,515,477
Ensembl chr 5:166,500,781...166,515,481

G

acyl-CoA binding domain containing 5

increases expression

Aldrin results in increased expression of ACBD5 mRNA

NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215

G

alkaline ceramidase 2

decreases expression

Aldrin results in decreased expression of ACER2 mRNA

NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614

G

ATP citrate lyase

increases expression

Aldrin results in increased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA synthetase short-chain family member 2

increases expression

Aldrin results in increased expression of ACSS2 mRNA

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

activin A receptor type 1C

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVR1C mRNA

NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327

G

activin A receptor like type 1

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVRL1 mRNA

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

G

adhesion G protein-coupled receptor B2

increases expression

Aldrin results in increased expression of ADGRB2 mRNA

NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540

G

alcohol dehydrogenase 4 (class II), pi polypeptide

increases expression

Aldrin results in increased expression of ADH4 mRNA

NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591

G

allograft inflammatory factor 1-like

increases expression

Aldrin results in increased expression of AIF1L mRNA

NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023

G

AIF family member 2

decreases expression

Aldrin results in decreased expression of AIFM2 mRNA

NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236

G

aldehyde dehydrogenase 18 family, member A1

increases expression

Aldrin results in increased expression of ALDH18A1 mRNA

NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890

G

ALK receptor tyrosine kinase

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ALK mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA

PMID:19422813 PMID:28263720

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

G

alkaline phosphatase, intestinal

decreases expression

Aldrin results in decreased expression of ALPI mRNA

NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877

G

alsin Rho guanine nucleotide exchange factor ALS2

increases expression

Aldrin results in increased expression of ALS2 mRNA

NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737

G

androgen receptor

multiple interactions
affects binding

Aldrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Aldrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]
Aldrin binds to AR protein

PMID:14565775 PMID:21295777 PMID:26022396

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

arylsulfatase G

increases expression

Aldrin results in increased expression of ARSG mRNA

NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941

G

atlastin GTPase 1

increases expression

Aldrin results in increased expression of ATL1 mRNA

NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204

G

basic helix-loop-helix family, member a15

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA

NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713

G

basigin

decreases expression

Aldrin results in decreased expression of BSG mRNA

NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387

G

calcium voltage-gated channel subunit alpha1 F

decreases expression

Aldrin results in decreased expression of CACNA1F mRNA

NCBI chr X:14,868,096...14,896,413
Ensembl chr X:14,868,024...14,896,413

G

calcium/calmodulin-dependent protein kinase ID

increases expression

Aldrin results in increased expression of CAMK1D mRNA

NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556

G

carbonic anhydrase 3

increases expression

Aldrin results in increased expression of CAR3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

caspase 14

increases expression

Aldrin results in increased expression of CASP14 mRNA

NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405

G

cellular communication network factor 1

increases expression

Aldrin results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cyclin B1

increases expression

Aldrin results in increased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

Cd200 molecule

increases expression

Aldrin results in increased expression of CD200 mRNA

NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648

G

cadherin 1

increases expression

Aldrin results in increased expression of CDH1 mRNA

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 17

increases expression

Aldrin results in increased expression of CDH17 mRNA

NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884

G

cyclin-dependent kinase 14

increases expression

Aldrin results in increased expression of CDK14 mRNA

NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861

G

cholinergic receptor nicotinic alpha 4 subunit

increases expression

Aldrin results in increased expression of CHRNA4 mRNA

NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957

G

cold inducible RNA binding protein

increases expression

Aldrin results in increased expression of CIRBP mRNA

NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818

G

claudin 2

increases expression

Aldrin results in increased expression of CLDN2 mRNA

NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838

G

Cnksr family member 3

increases expression

Aldrin results in increased expression of CNKSR3 mRNA

NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635

G

collagen type XV alpha 1 chain

increases expression

Aldrin results in increased expression of COL15A1 mRNA

NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591

G

collagen type XXVII alpha 1 chain

increases expression

Aldrin results in increased expression of COL27A1 mRNA

NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174

G

cytochrome c oxidase assembly factor COX20

increases expression

Aldrin results in increased expression of COX20 mRNA

NCBI chr13:90,065,900...90,075,386
Ensembl chr14:6,567,733...6,568,056

G

cysteine and glycine-rich protein 2

decreases expression

Aldrin results in decreased expression of CSRP2 mRNA

NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745

G

cytochrome P450, family 19, subfamily a, polypeptide 1

increases expression
increases activity

Aldrin results in increased expression of CYP19A1 mRNA
Aldrin results in increased activity of CYP19A1 protein

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 26, subfamily a, polypeptide 1

increases expression
multiple interactions

Aldrin results in increased expression of CYP26A1 mRNA
AGN 193109 inhibits the reaction [Aldrin results in increased expression of CYP26A1 mRNA]

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression

Aldrin results in increased expression of CYP2B6 protein

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 39, subfamily a, polypeptide 1

decreases expression

Aldrin results in decreased expression of CYP39A1 mRNA

NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression

Aldrin results in increased expression of CYP3A4 protein

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450 family 7 subfamily B member 1

increases expression

Aldrin results in increased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

dopa decarboxylase

increases expression

Aldrin results in increased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DEP domain containing 7

increases expression

Aldrin results in increased expression of DEPDC7 mRNA

NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124

G

DEXH-box helicase 58

increases expression

Aldrin results in increased expression of DHX58 mRNA

NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525

G

dickkopf WNT signaling pathway inhibitor 3

decreases expression

Aldrin results in decreased expression of DKK3 mRNA

NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590

G

dentin matrix acidic phosphoprotein 1

increases expression

Aldrin results in increased expression of DMP1 mRNA

NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323

G

endonuclease/exonuclease/phosphatase family domain containing 1

increases expression

Aldrin results in increased expression of EEPD1 mRNA

NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340

G

Eph receptor A3

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA

NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900

G

Eph receptor A8

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA

NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399

G

erb-b2 receptor tyrosine kinase 3

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

ERI1 exoribonuclease family member 3

increases expression

Aldrin results in increased expression of ERI3 mRNA

NCBI chr 5:131,016,146...131,143,347
Ensembl chr 5:131,016,126...131,143,329

G

estrogen receptor 1

affects binding
increases expression
increases activity
multiple interactions

Aldrin binds to ESR1 protein
Aldrin results in increased expression of ESR1 mRNA
Aldrin results in increased activity of ESR1 protein
[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; Aldrin inhibits the reaction [Estradiol binds to ESR1 protein]

PMID:14579009 PMID:15064155 PMID:21295777 PMID:26022396

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

Aldrin binds to and results in decreased activity of ESR2 protein

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

ETHE1, persulfide dioxygenase

increases expression

Aldrin results in increased expression of ETHE1 mRNA

NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052

G

coagulation factor VII

increases expression

Aldrin results in increased expression of F7 mRNA

NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610

G

family with sequence similarity 133, member B

decreases expression

Aldrin results in decreased expression of FAM133B mRNA

NCBI chr 4:30,589,646...30,616,291
Ensembl chr 4:30,589,635...30,616,040

G

fatty acyl CoA reductase 1

decreases expression

Aldrin results in decreased expression of FAR1 mRNA

NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730

G

F-box protein 31

decreases expression

Aldrin results in decreased expression of FBXO31 mRNA

NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010

G

FKBP prolyl isomerase 5

decreases expression

Aldrin results in decreased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

flavin containing dimethylaniline monoxygenase 2

decreases expression

Aldrin results in decreased expression of FMO2 mRNA

NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308

G

folate receptor alpha

increases expression

Aldrin results in increased expression of FOLR1 mRNA

NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667

G

forkhead box C2

increases expression

Aldrin results in increased expression of FOXC2 mRNA

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

G

FERM domain containing 4B

increases expression

Aldrin results in increased expression of FRMD4B mRNA

NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197

G

fibroblast growth factor receptor substrate 3

increases expression

Aldrin results in increased expression of FRS3 mRNA

NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382

G

guanylate binding protein family member 6

increases expression

Aldrin results in increased expression of GBP9 mRNA

NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062

G

glycerophosphodiester phosphodiesterase 1

decreases expression

Aldrin results in decreased expression of GDE1 mRNA

NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429

G

GDNF family receptor alpha 1

decreases expression
multiple interactions

Aldrin results in decreased expression of GFRA1 mRNA
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA

PMID:18579281 PMID:28263720

NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473

G

gap junction protein, alpha 4

decreases expression

Aldrin results in decreased expression of GJA4 mRNA

NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925

G

GDP-mannose pyrophosphorylase B

increases expression

Aldrin results in increased expression of GMPPB mRNA

NCBI chr 8:108,737,429...108,740,437
Ensembl chr 8:108,693,060...108,767,286

G

G protein subunit beta 5

increases expression

Aldrin results in increased expression of GNB5 mRNA

NCBI chr 8:76,076,120...76,105,069
Ensembl chr 8:76,073,306...76,105,069

G

glutamic-oxaloacetic transaminase 1

decreases expression

Aldrin results in decreased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycoprotein A33

increases expression

Aldrin results in increased expression of GPA33 mRNA

NCBI chr13:78,381,141...78,414,765
Ensembl chr13:78,381,141...78,414,765

G

glycerol-3-phosphate acyltransferase, mitochondrial

increases expression

Aldrin results in increased expression of GPAM mRNA

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

G

G protein-coupled receptor 12

increases expression

Aldrin results in increased expression of GPR12 mRNA

NCBI chr12:8,522,709...8,525,875
Ensembl chr12:8,522,953...8,527,973

G

growth factor receptor bound protein 14

increases expression

Aldrin results in increased expression of GRB14 mRNA

NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889

G

glutamate ionotropic receptor AMPA type subunit 3

increases expression

Aldrin results in increased expression of GRIA3 mRNA

NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096

G

heme oxygenase 1

decreases expression

Aldrin results in decreased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

homeobox C8

increases expression

Aldrin results in increased expression of HOXC8 mRNA

NCBI chr 7:134,127,937...134,130,503
Ensembl chr 7:134,127,913...134,130,503

G

hydroxysteroid (17-beta) dehydrogenase 2

increases expression

Aldrin results in increased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

heat shock protein family A (Hsp70) member 8

decreases expression

Aldrin results in decreased expression of HSPA8 mRNA

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family B (small) member 1

decreases expression

Aldrin results in decreased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

inhibitor of DNA binding 1

decreases expression

Aldrin results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

Indian hedgehog signaling molecule

increases expression

Aldrin results in increased expression of IHH mRNA

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

G

inhibitor of nuclear factor kappa B kinase subunit epsilon

increases expression

Aldrin results in increased expression of IKBKE mRNA

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

G

interleukin 1 receptor type 1

decreases expression

Aldrin results in decreased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 36, alpha

increases expression

Aldrin results in increased expression of IL36A mRNA

NCBI chr 3:6,996,851...7,001,400
Ensembl chr 3:6,996,851...7,001,400

G

INSC, spindle orientation adaptor protein

increases expression

Aldrin results in increased expression of INSC mRNA

NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:168,993,032...169,100,433

G

influenza virus NS1A binding protein

decreases expression

Aldrin results in decreased expression of IVNS1ABP mRNA

NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701

G

potassium voltage-gated channel subfamily D member 2

increases expression

Aldrin results in increased expression of KCND2 mRNA

NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728

G

KIT proto-oncogene receptor tyrosine kinase

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA

PMID:19422813 PMID:28263720

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

kelch-like family member 31

increases expression

Aldrin results in increased expression of KLHL31 mRNA

NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873

G

laminin subunit alpha 5

increases expression

Aldrin results in increased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

galectin 9

increases expression

Aldrin results in increased expression of LGALS9 mRNA

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

G

LIM and calponin homology domains 1

decreases expression

Aldrin results in decreased expression of LIMCH1 mRNA

NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191

G

LIM domain only 1

increases expression

Aldrin results in increased expression of LMO1 mRNA

NCBI chr 1:163,132,338...163,168,521
Ensembl chr 1:163,132,339...163,168,522

G

lon peptidase 2, peroxisomal

increases expression

Aldrin results in increased expression of LONP2 mRNA

NCBI chr19:20,407,475...20,498,985
Ensembl chr19:20,407,477...20,499,014

G

lysophosphatidic acid receptor 4

decreases expression

Aldrin results in decreased expression of LPAR4 mRNA

NCBI chr X:72,033,486...72,046,978
Ensembl chr X:72,033,486...72,046,977

G

lipin 1

decreases expression

Aldrin results in decreased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

leucine rich repeat containing 2

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA

NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185

G

leucine rich repeat containing 49

decreases expression

Aldrin results in decreased expression of LRRC49 mRNA

NCBI chr 8:61,053,264...61,160,695
Ensembl chr 8:61,053,267...61,160,850

G

lanosterol synthase

increases expression

Aldrin results in increased expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

mal, T-cell differentiation protein 2

increases expression

Aldrin results in increased expression of MAL2 mRNA

NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429

G

microtubule-associated protein 1 light chain 3 beta

decreases expression

Aldrin results in decreased expression of MAP1LC3B mRNA

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

microtubule-associated protein 4

increases expression

Aldrin results in increased expression of MAP4 mRNA

NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362

G

mitogen-activated protein kinase 8 interacting protein 2

increases expression

Aldrin results in increased expression of MAPK8IP2 mRNA

NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982

G

muscleblind-like splicing regulator 2

decreases expression

Aldrin results in decreased expression of MBNL2 mRNA

NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937

G

malic enzyme 1

increases expression

Aldrin results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

Meis homeobox 2

increases expression

Aldrin results in increased expression of MEIS2 mRNA

NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696

G

MER proto-oncogene, tyrosine kinase

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA

NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554

G

major facilitator superfamily domain containing 13A

increases expression

Aldrin results in increased expression of MFSD13A mRNA

NCBI chr 1:245,216,610...245,236,314
Ensembl chr 1:245,217,067...245,236,767

G

multiple PDZ domain crumbs cell polarity complex component

increases expression

Aldrin results in increased expression of MPDZ mRNA

NCBI chr 5:95,766,112...95,920,531
Ensembl chr 5:95,766,118...95,920,499

G

metallothionein 1

decreases expression

Aldrin results in decreased expression of MT1 mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

metallothionein 4

decreases expression

Aldrin results in decreased expression of MT4 mRNA

NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909

G

microtubule crosslinking factor 1

increases expression

Aldrin results in increased expression of MTCL1 mRNA

NCBI chr 9:106,305,282...106,441,782
Ensembl chr 9:106,321,098...106,442,203

G

mevalonate diphosphate decarboxylase

increases expression

Aldrin results in increased expression of MVD mRNA

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

myosin binding protein H

increases expression

Aldrin results in increased expression of MYBPH mRNA

NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893

G

neutrophil cytosolic factor 1

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NCF1 mRNA]

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

G

NADH:ubiquinone oxidoreductase subunit B4

decreases expression

Aldrin results in decreased expression of NDUFB4 mRNA

NCBI chr11:63,063,723...63,070,426
Ensembl chr11:63,063,795...63,070,425

G

neurofilament light chain

increases expression

Aldrin results in increased expression of NEFL mRNA

NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793

G

nerve growth factor receptor

increases expression

Aldrin results in increased expression of NGFR mRNA

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

NHS-like 1

increases expression

Aldrin results in increased expression of NHSL1 mRNA

NCBI chr 1:12,956,525...13,188,580
Ensembl chr 1:12,956,021...13,187,547

G

niban apoptosis regulator 2

increases expression

Aldrin results in increased expression of NIBAN2 mRNA

NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293

G

nucleolar pre-rRNA processing protein NIP7

decreases expression

Aldrin results in decreased expression of NIP7 mRNA

NCBI chr19:34,962,557...34,964,700
Ensembl chr19:34,962,557...34,964,711

G

NIPA-like domain containing 4

increases expression

Aldrin results in increased expression of NIPAL4 mRNA

NCBI chr10:30,583,926...30,600,640
Ensembl chr10:30,583,926...30,600,640

G

nitric oxide synthase 3

increases expression
multiple interactions

Aldrin results in increased expression of NOS3 mRNA
Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NOS3 mRNA]

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity

Aldrin binds to and results in increased activity of NR1I2 protein
Aldrin results in increased activity of NR1I2 protein

PMID:15548381 PMID:21115097

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases activity

Aldrin results in increased activity of NR1I3 protein

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

neuregulin 4

decreases expression

Aldrin results in decreased expression of NRG4 mRNA

NCBI chr 8:55,586,253...55,677,829
Ensembl chr 8:55,592,893...55,677,483

G

neurotrophic receptor tyrosine kinase 1

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

neurotrophic receptor tyrosine kinase 2

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

G

neurotensin

increases expression

Aldrin results in increased expression of NTS mRNA

NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423

G

nudix hydrolase 7

increases expression

Aldrin results in increased expression of NUDT7 mRNA

NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081

G

osteoglycin

decreases expression

Aldrin results in decreased expression of OGN mRNA

NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739

G

olfactomedin-like 2B

increases expression

Aldrin results in increased expression of OLFML2B mRNA

NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607

G

olfactory receptor family 5 subfamily B member 99

increases expression

Aldrin results in increased expression of OR5B99 mRNA

NCBI chr 1:210,136,841...210,137,767
Ensembl chr 1:210,132,946...210,138,365

G

odd-skipped related transciption factor 2

increases expression

Aldrin results in increased expression of OSR2 mRNA

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

G

proprotein convertase subtilisin/kexin type 9

increases expression

Aldrin results in increased expression of PCSK9 mRNA

NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688

G

platelet derived growth factor receptor alpha

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRA mRNA

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

G

platelet derived growth factor receptor beta

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA

PMID:19422813 PMID:28263720

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

phosphofructokinase, platelet

decreases expression

Aldrin results in decreased expression of PFKP mRNA

NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018

G

progesterone receptor

multiple interactions
affects binding

Aldrin inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; Aldrin inhibits the reaction [Progesterone binds to PGR protein]
Aldrin binds to PGR protein

PMID:14579009 PMID:26022396

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

pipecolic acid and sarcosine oxidase

increases expression

Aldrin results in increased expression of PIPOX mRNA

NCBI chr10:62,769,874...62,783,484
Ensembl chr10:62,769,900...62,782,370

G

polycystin 1 like 2

decreases expression

Aldrin results in decreased expression of PKD1L2 mRNA

NCBI chr19:45,049,713...45,136,503
Ensembl chr19:45,049,719...45,135,532

G

phospholipase C, eta 2

increases expression

Aldrin results in increased expression of PLCH2 mRNA

NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356

G

perilipin 4

decreases expression

Aldrin results in decreased expression of PLIN4 mRNA

NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056

G

polo-like kinase 3

decreases expression

Aldrin results in decreased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

plexin D1

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA

NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244

G

pancreatic lipase related protein 2

increases expression

Aldrin results in increased expression of PNLIPRP2 mRNA

NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434

G

patatin-like phospholipase domain containing 2

decreases expression

Aldrin results in decreased expression of PNPLA2 mRNA

NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805

G

cytochrome p450 oxidoreductase

decreases expression

Aldrin results in decreased expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

protein phosphatase 1, regulatory subunit 10

decreases expression

Aldrin results in decreased expression of PPP1R10 mRNA

NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611

G

protein phosphatase 1, regulatory subunit 3G

decreases expression

Aldrin results in decreased expression of PPP1R3G mRNA

NCBI chr17:28,874,956...28,878,288
Ensembl chr17:28,876,482...28,877,525

G

protein kinase D1

increases expression

Aldrin results in increased expression of PRKD1 mRNA

NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042

G

prokineticin 1

increases expression

Aldrin results in increased expression of PROK1 mRNA

NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250

G

phosphoserine aminotransferase 1

increases expression

Aldrin results in increased expression of PSAT1 mRNA

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

presenilin 2

increases expression

Aldrin results in increased expression of PSEN2 mRNA

NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174

G

protein tyrosine phosphatase 4A1

decreases expression

Aldrin results in decreased expression of PTP4A1 mRNA

NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964

G

protein tyrosine phosphatase, receptor type, F

increases expression

Aldrin results in increased expression of PTPRF mRNA

NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023

G

glutaminyl-peptide cyclotransferase

increases expression

Aldrin results in increased expression of QPCT mRNA

NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711

G

retinoic acid receptor, beta

increases expression

Aldrin results in increased expression of RARB mRNA

NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288

G

retinoic acid receptor, gamma

increases expression

Aldrin results in increased expression of RARG mRNA

NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177

G

ret proto-oncogene

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA

NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176

G

reticulophagy regulator 1

decreases expression

Aldrin results in decreased expression of RETREG1 mRNA

NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898

G

ribosomal protein L39 like 1

increases expression

Aldrin results in increased expression of RPL39L mRNA

NCBI chr10:5,455,712...5,459,828
Ensembl chr10:5,454,559...5,462,029

G

retinoid X receptor gamma

increases expression

Aldrin results in increased expression of RXRG mRNA

NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167

G

S100 calcium binding protein A10

increases expression

Aldrin results in increased expression of S100A10 mRNA

NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661

G

S100 calcium binding protein A9

decreases expression

Aldrin results in decreased expression of S100A9 mRNA

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

spalt-like transcription factor 2

increases expression

Aldrin results in increased expression of SALL2 mRNA

NCBI chr15:25,021,345...25,038,918
Ensembl chr15:25,021,345...25,038,918

G

sterol-C5-desaturase

increases expression

Aldrin results in increased expression of SC5D mRNA

NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273

G

scinderin

increases expression

Aldrin results in increased expression of SCIN mRNA

NCBI chr 6:57,109,500...57,188,123
Ensembl chr 6:57,109,403...57,188,242

G

short chain dehydrogenase/reductase family 42E, member 1

increases expression

Aldrin results in increased expression of SDR42E1 mRNA

NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901

G

septin 9

increases expression

Aldrin results in increased expression of SEPTIN9 mRNA

NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055

G

serpin family A member 12

increases expression

Aldrin results in increased expression of SERPINA12 mRNA

NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271

G

solute carrier family 10 member 1

increases expression

Aldrin results in increased expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 25 member 32

decreases expression

Aldrin results in decreased expression of SLC25A32 mRNA

NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:70,142,964...70,160,770

G

solute carrier family 36 member 2

increases expression

Aldrin results in increased expression of SLC36A2 mRNA

NCBI chr10:39,278,002...39,306,082
Ensembl chr10:39,278,046...39,306,082

G

solute carrier family 7 member 2

decreases expression

Aldrin results in decreased expression of SLC7A2 mRNA

NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784

G

small integral membrane protein 3

increases expression

Aldrin results in increased expression of SMIM3 mRNA

NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416

G

sorting nexin 7

increases expression

Aldrin results in increased expression of SNX7 mRNA

NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:205,842,837...205,927,763

G

sorbin and SH3 domain containing 3

decreases expression

Aldrin results in decreased expression of SORBS3 mRNA

NCBI chr15:45,252,921...45,284,758
Ensembl chr15:45,253,379...45,284,758

G

serine peptidase inhibitor, Kunitz type 1

decreases expression

Aldrin results in decreased expression of SPINT1 mRNA

NCBI chr 3:106,231,082...106,244,121
Ensembl chr 3:106,231,444...106,244,119

G

spondin 2

increases expression

Aldrin results in increased expression of SPON2 mRNA

NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996

G

sterol regulatory element binding transcription factor 1

increases expression

Aldrin results in increased expression of SREBF1 mRNA

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

decreases expression

Aldrin results in decreased expression of ST3GAL5 mRNA

NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558

G

synaptotagmin 5

increases expression

Aldrin results in increased expression of SYT5 mRNA

NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067

G

transforming, acidic coiled-coil containing protein 2

decreases expression

Aldrin results in decreased expression of TACC2 mRNA

NCBI chr 1:185,139,223...185,327,881
Ensembl chr 1:185,116,111...185,327,881

G

transcription elongation factor A2

decreases expression

Aldrin results in decreased expression of TCEA2 mRNA

NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:168,796,331...168,804,116

G

tet methylcytosine dioxygenase 2

increases response to substance

TET2 gene SNP results in increased susceptibility to Aldrin

NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534

G

triokinase and FMN cyclase

increases expression

Aldrin results in increased expression of TKFC mRNA

NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737

G

target of myb1 like 2 membrane trafficking protein

decreases expression

Aldrin results in decreased expression of TOM1L2 mRNA

NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032

G

trafficking kinesin protein 2

decreases expression

Aldrin results in decreased expression of TRAK2 mRNA

NCBI chr 9:60,348,531...60,414,036
Ensembl chr 9:60,350,012...60,413,996

G

TLR4 interactor with leucine-rich repeats

decreases expression

Aldrin results in decreased expression of TRIL mRNA

NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172

G

TSC22 domain family, member 1

increases expression

Aldrin results in increased expression of TSC22D1 mRNA

NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958

G

tetratricopeptide repeat domain 39C

increases expression

Aldrin results in increased expression of TTC39C mRNA

NCBI chr18:3,768,802...3,887,932
Ensembl chr18:3,805,183...3,887,930

G

UDP-glucose 6-dehydrogenase

increases expression

Aldrin results in increased expression of UGDH mRNA

NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354

G

UDP glucuronosyltransferase 2 family, polypeptide B1

increases expression

Aldrin results in increased expression of UGT2B1 mRNA

NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986

G

ubiquitin specific peptidase 2

decreases expression

Aldrin results in decreased expression of USP2 mRNA

NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331

G

uronyl-2-sulfotransferase

increases expression

Aldrin results in increased expression of UST mRNA

NCBI chr 1:2,666,983...2,962,276
Ensembl chr 1:2,669,592...2,962,044

G

vesicle-associated membrane protein 1

decreases expression

Aldrin results in decreased expression of VAMP1 mRNA

NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349

G

VANGL planar cell polarity protein 2

increases expression

Aldrin results in increased expression of VANGL2 mRNA

NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378

G

vascular cell adhesion molecule 1

decreases expression

Aldrin results in decreased expression of VCAM1 mRNA

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

G

ventricular zone expressed PH domain-containing 1

increases expression

Aldrin results in increased expression of VEPH1 mRNA

NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266

G

yippee-like 1

increases expression

Aldrin results in increased expression of YPEL1 mRNA

NCBI chr11:83,921,799...83,936,409

G

zinc fingers and homeoboxes 3

decreases expression

Aldrin results in decreased expression of ZHX3 mRNA

NCBI chr 3:149,417,787...149,548,671
Ensembl chr 3:149,417,818...149,527,079

diafenthiuron

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

OPA1, mitochondrial dynamin like GTPase

decreases cleavage

diafenthiuron results in decreased cleavage of OPA1 protein

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

diclofop-methyl

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

multiple interactions

[dichlorfop-methyl co-treated with difenoconazole] results in decreased activity of ACHE protein

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

albumin

affects binding

dichlorfop-methyl binds to ALB protein

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

catalase

increases activity

dichlorfop-methyl results in increased activity of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

peroxisome proliferator activated receptor alpha

multiple interactions

dichlorfop-methyl binds to and results in increased activity of PPARA protein

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

dieldrin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase

decreases expression

Dieldrin results in decreased expression of AADAC mRNA

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

ATP binding cassette subfamily B member 1A

increases expression

Dieldrin results in increased expression of ABCB1 mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 1

increases expression

Dieldrin results in increased expression of ABCC1 mRNA

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

ATP binding cassette subfamily C member 2

increases expression

Dieldrin results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily G member 2

increases expression

Dieldrin results in increased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ATP citrate lyase

affects expression

Dieldrin affects the expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA synthetase medium-chain family member 3

decreases expression

Dieldrin results in decreased expression of ACSM3 mRNA

NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184

G

actinin, alpha 1

affects expression

Dieldrin affects the expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

actinin alpha 4

affects methylation

Dieldrin affects the methylation of ACTN4 gene

NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847

G

activin A receptor type 1C

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVR1C mRNA

NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327

G

activin A receptor like type 1

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVRL1 mRNA

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

G

ADAM metallopeptidase domain 15

decreases expression

Dieldrin results in decreased expression of ADAM15 mRNA

NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113

G

ADAM metallopeptidase domain 17

affects expression

Dieldrin affects the expression of ADAM17 mRNA

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

G

adrenoceptor alpha 2B

decreases expression

Dieldrin results in decreased expression of ADRA2B mRNA

NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355

G

adrenoceptor beta 1

affects expression

Dieldrin affects the expression of ADRB1 mRNA

NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259

G

adrenoceptor beta 2

affects expression

Dieldrin affects the expression of ADRB2 mRNA

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

ALF transcription elongation factor 3

affects methylation

Dieldrin affects the methylation of AFF3 gene

NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247

G

aryl hydrocarbon receptor

increases activity

Dieldrin results in increased activity of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

AIF family member 2

affects expression

Dieldrin affects the expression of AIFM2 mRNA

NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236

G

AKT serine/threonine kinase 2

affects expression

Dieldrin affects the expression of AKT2 mRNA

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

G

ALK receptor tyrosine kinase

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ALK mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA

PMID:19422813 PMID:28263720

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

G

arachidonate 15-lipoxygenase

affects expression

Dieldrin affects the expression of ALOX15 mRNA

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

G

adhesion molecule with Ig like domain 2

affects expression

Dieldrin affects the expression of AMIGO2 mRNA

NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695

G

anoctamin 1

affects methylation

Dieldrin affects the methylation of ANO1 gene

NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069

G

annexin A1

affects expression

Dieldrin affects the expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

aldehyde oxidase 1

increases expression
multiple interactions

Dieldrin results in increased expression of AOX1 mRNA
NR1I3 protein affects the reaction [Dieldrin results in increased expression of AOX1 mRNA]

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

apoptotic peptidase activating factor 1

affects expression

Dieldrin affects the expression of APAF1 mRNA

NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540

G

amyloid beta precursor protein binding family B member 1

affects expression

Dieldrin affects the expression of APBB1 mRNA

NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627

G

amyloid beta precursor protein binding family B member 2

affects expression

Dieldrin affects the expression of APBB2 mRNA

NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495

G

amyloid beta precursor protein binding family B member 3

affects expression

Dieldrin affects the expression of APBB3 mRNA

NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094

G

apurinic/apyrimidinic endodeoxyribonuclease 2

affects expression

Dieldrin affects the expression of APEX2 mRNA

NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439

G

apoptosis inhibitor 5

affects expression

Dieldrin affects the expression of API5 mRNA

NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:80,378,096...80,403,264

G

amyloid beta precursor like protein 1

affects expression

Dieldrin affects the expression of APLP1 mRNA

NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155

G

apolipoprotein H

affects methylation

Dieldrin affects the methylation of APOH gene

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

G

amyloid beta precursor protein

affects expression

Dieldrin affects the expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 11

decreases expression

Dieldrin results in decreased expression of AQP11 mRNA

NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725

G

aquaporin 9

decreases expression

Dieldrin results in decreased expression of AQP9 mRNA

NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395

G

androgen receptor

multiple interactions

Dieldrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Dieldrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dieldrin inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [Dieldrin results in increased activity of AR protein]

PMID:15064155 PMID:18324785 PMID:21295777 PMID:26022396

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

A-Raf proto-oncogene, serine/threonine kinase

affects expression

Dieldrin affects the expression of ARAF mRNA

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

G

activity-regulated cytoskeleton-associated protein

increases expression

Dieldrin results in increased expression of ARC mRNA

NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378

G

Rac/Cdc42 guanine nucleotide exchange factor 6

affects expression

Dieldrin affects the expression of ARHGEF6 mRNA

NCBI chr X:135,145,447...135,264,636
Ensembl chr X:135,146,786...135,275,304

G

ariadne RBR E3 ubiquitin protein ligase 2

decreases response to substance

ARIH2 gene mutant form results in decreased susceptibility to Dieldrin

NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852

G

activating transcription factor 3

increases expression

Dieldrin results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

autophagy related 10

increases response to substance

ATG10 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233

G

autophagy related 101

increases response to substance

ATG101 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633

G

autophagy related 4B, cysteine peptidase

increases response to substance

ATG4B gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103

G

autophagy related 5

affects methylation

Dieldrin affects the methylation of ATG5 gene

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

autophagy related 9A

increases response to substance

ATG9A gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 9:76,677,403...76,688,050
Ensembl chr 9:76,677,404...76,687,986

G

ATM serine/threonine kinase

affects expression

Dieldrin affects the expression of ATM mRNA

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase cation transporting 13A2

decreases expression

Dieldrin results in decreased expression of ATP13A2 mRNA

NCBI chr 5:153,292,722...153,312,143
Ensembl chr 5:153,292,751...153,312,139

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

decreases expression

Dieldrin results in decreased expression of ATP2A2 mRNA

NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101

G

aurora kinase A

affects expression
increases expression

Dieldrin affects the expression of AURKA mRNA
Dieldrin results in increased expression of AURKA mRNA

PMID:22546817 PMID:23153324

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

aurora kinase B

affects expression

Dieldrin affects the expression of AURKB mRNA

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

G

apoptosis and caspase activation inhibitor

affects expression

Dieldrin affects the expression of AVEN mRNA

NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634

G

arginine vasopressin receptor 1B

increases expression

Dieldrin results in increased expression of AVPR1B mRNA

NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792

G

BRISC and BRCA1 A complex member 2

affects expression

Dieldrin affects the expression of BABAM2 mRNA

NCBI chr 6:24,369,021...24,788,416
Ensembl chr 6:24,369,022...24,833,951

G

BAG cochaperone 1

affects expression

Dieldrin affects the expression of BAG1 mRNA

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

G

BAG cochaperone 3

affects expression

Dieldrin affects the expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BCL2-antagonist/killer 1

affects expression

Dieldrin affects the expression of BAK1 mRNA

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

BCL2 associated X, apoptosis regulator

affects expression

Dieldrin affects the expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

affects expression

Dieldrin affects the expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

branched chain amino acid transaminase 1

increases expression

Dieldrin results in increased expression of BCAT1 mRNA

NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597

G

BCL2, apoptosis regulator

decreases response to substance
multiple interactions

BCL2 protein results in decreased susceptibility to Dieldrin
BCL2 protein inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Dieldrin results in increased activity of PRKCD protein]

PMID:15033812 PMID:15183012

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

affects expression

Dieldrin affects the expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

Bcl2-like 10

affects expression

Dieldrin affects the expression of BCL2L10 mRNA

NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367

G

Bcl2-like 11

affects expression

Dieldrin affects the expression of BCL2L11 mRNA

NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068

G

Bcl2-like 13

affects expression

Dieldrin affects the expression of BCL2L13 mRNA

NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985

G

Bcl2-like 14

affects expression

Dieldrin affects the expression of BCL2L14 mRNA

NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086

G

BCL3, transcription coactivator

affects expression

Dieldrin affects the expression of BCL3 mRNA

NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607

G

BCL6, transcription repressor

affects expression

Dieldrin affects the expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

brain expressed X-linked 3

increases expression
affects expression

Dieldrin results in increased expression of BEX3 mRNA
Dieldrin affects the expression of BEX3 mRNA

PMID:19130878 PMID:22546817

NCBI chr X:99,273,270...99,274,799
Ensembl chr X:99,273,161...99,274,800

G

bifunctional apoptosis regulator

affects expression

Dieldrin affects the expression of BFAR mRNA

NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038

G

basic helix-loop-helix family, member a15

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA

NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713

G

BH3 interacting domain death agonist

affects expression

Dieldrin affects the expression of BID mRNA

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

BCL2-interacting killer

affects expression

Dieldrin affects the expression of BIK mRNA

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

bridging integrator 1

affects expression

Dieldrin affects the expression of BIN1 mRNA

NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263

G

bridging integrator 3

affects expression

Dieldrin affects the expression of BIN3 mRNA

NCBI chr15:45,173,725...45,212,607
Ensembl chr15:45,173,732...45,212,604

G

baculoviral IAP repeat-containing 3

affects expression

Dieldrin affects the expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

affects expression

Dieldrin affects the expression of BIRC5 mRNA

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

baculoviral IAP repeat-containing 6

increases response to substance

BIRC6 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434

G

BCL2 interacting protein 3

affects expression

Dieldrin affects the expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

BCL2 interacting protein 3 like

affects expression

Dieldrin affects the expression of BNIP3L mRNA

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

G

BRCA1, DNA repair associated

affects expression

Dieldrin affects the expression of BRCA1 mRNA

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

BMP/retinoic acid inducible neural specific 1

affects expression

Dieldrin affects the expression of BRINP1 mRNA

NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150

G

BMP/retinoic acid inducible neural specific 2

affects expression

Dieldrin affects the expression of BRINP2 mRNA

NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810

G

BTG anti-proliferation factor 1

affects expression

Dieldrin affects the expression of BTG1 mRNA

NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649

G

BTG anti-proliferation factor 2

increases expression

Dieldrin results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

BTG anti-proliferation factor 3

affects expression

Dieldrin affects the expression of BTG3 mRNA

NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170

G

basic leucine zipper and W2 domains 1

affects expression

Dieldrin affects the expression of BZW1 mRNA

NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430

G

Cdk5 and Abl enzyme substrate 1

affects expression

Dieldrin affects the expression of CABLES1 mRNA

NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,075,524...3,181,181

G

calmodulin 2

affects expression

Dieldrin affects the expression of CALM2 mRNA

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

G

calcium/calmodulin-dependent protein kinase II alpha

affects expression

Dieldrin affects the expression of CAMK2A mRNA

NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994

G

calcium/calmodulin-dependent protein kinase II beta

affects expression
affects methylation

Dieldrin affects the expression of CAMK2B mRNA
Dieldrin affects the methylation of CAMK2B gene

PMID:22546817 PMID:38995845

NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994

G

calcium/calmodulin-dependent protein kinase II gamma

affects expression

Dieldrin affects the expression of CAMK2G mRNA

NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050

G

cullin-associated and neddylation-dissociated 1

affects expression

Dieldrin affects the expression of CAND1 mRNA

NCBI chr 7:54,681,114...54,719,002
Ensembl chr 7:54,680,900...54,718,993

G

caspase recruitment domain family, member 9

affects expression

Dieldrin affects the expression of CARD9 mRNA

NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237

G

caspase 12

affects expression

Dieldrin affects the expression of CASP12 mRNA

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

decreases activity
increases activity
multiple interactions

Dieldrin results in decreased activity of CASP3 protein
Dieldrin results in increased activity of CASP3 protein
BCL2 protein inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]
[Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP3 protein; Dieldrin inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]; Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]; FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; rottlerin inhibits the reaction [Dieldrin results in increased activity of CASP3 protein]; SNCA protein promotes the reaction [Dieldrin results in increased expression of CASP3 protein]

PMID:10200566 PMID:12831855 PMID:15033812 PMID:15183012 PMID:15987830 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

affects expression

Dieldrin affects the expression of CASP4 mRNA

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 7

multiple interactions
affects expression

[Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP7 protein
Dieldrin affects the expression of CASP7 mRNA

PMID:20036686 PMID:22546817

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

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caspase 8

affects expression

Dieldrin affects the expression of CASP8 mRNA

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

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caspase 8 associated protein 2

affects expression

Dieldrin affects the expression of CASP8AP2 mRNA

NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275

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caspase 9

increases activity

Dieldrin results in increased activity of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

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CBFA2/RUNX1 partner transcriptional co-repressor 3

affects methylation

Dieldrin affects the methylation of CBFA2T3 gene

NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610

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Cbl proto-oncogene

decreases response to substance

CBL gene mutant form results in decreased susceptibility to Dieldrin

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

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chromobox 6

decreases expression

Dieldrin results in decreased expression of CBX6 mRNA

NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091

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cholecystokinin B receptor

increases expression

Dieldrin results in increased expression of CCKBR mRNA

NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881

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cyclin B1

affects expression
increases expression

Dieldrin affects the expression of CCNB1 mRNA
Dieldrin results in increased expression of CCNB1 mRNA

PMID:22546817 PMID:23153324

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

increases expression

Dieldrin results in increased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

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cyclin D1

affects expression

Dieldrin affects the expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

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cyclin E1

affects expression

Dieldrin affects the expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

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cyclin E2

affects expression

Dieldrin affects the expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

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cyclin F

affects expression

Dieldrin affects the expression of CCNF mRNA

NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101

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cyclin H

affects expression

Dieldrin affects the expression of CCNH mRNA

NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819

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cyclin J

affects expression

Dieldrin affects the expression of CCNJ mRNA

NCBI chr 1:239,659,588...239,677,367

G

cyclin T2

affects expression

Dieldrin affects the expression of CCNT2 mRNA

NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019

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cell cycle progression 1

affects expression

Dieldrin affects the expression of CCPG1 mRNA

NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430

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CD3 gamma subunit of T-cell receptor complex

affects expression

Dieldrin affects the expression of CD3G mRNA

NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147

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Cd69 molecule

increases expression

Dieldrin results in increased expression of CD69 mRNA

NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542

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cell division cycle 20

affects expression

Dieldrin affects the expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

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cell division cycle 23

affects expression

Dieldrin affects the expression of CDC23 mRNA

NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163

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cell division cycle 25B

affects expression

Dieldrin affects the expression of CDC25B mRNA

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

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cell division cycle 25C

affects expression

Dieldrin affects the expression of CDC25C mRNA

NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185

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cell division cycle 26

affects expression

Dieldrin affects the expression of CDC26 mRNA

NCBI chr 5:75,844,852...75,859,830

G

cell division cycle 34, ubiqiutin conjugating enzyme

affects expression

Dieldrin affects the expression of CDC34 mRNA

NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186

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cell division cycle 37-like 1

affects expression

Dieldrin affects the expression of CDC37L1 mRNA

NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175

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cell division cycle 6

affects expression

Dieldrin affects the expression of CDC6 mRNA

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cell division cycle 7

affects expression

Dieldrin affects the expression of CDC7 mRNA

NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778

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cell division cycle associated 2

affects expression

Dieldrin affects the expression of CDCA2 mRNA

NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611

G

cell division cycle associated 3

affects expression

Dieldrin affects the expression of CDCA3 mRNA

NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799

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cell division cycle associated 4

affects expression

Dieldrin affects the expression of CDCA4 mRNA

NCBI chr 6:131,892,305...131,901,571
Ensembl chr 6:131,892,087...131,901,564

G

cell division cycle associated 8

increases expression

Dieldrin results in increased expression of CDCA8 mRNA

NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629

G

cadherin 13

affects methylation

Dieldrin affects the methylation of CDH13 gene

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cadherin 2

decreases expression

Dieldrin results in decreased expression of CDH2 protein

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cyclin-dependent kinase 1

affects expression

Dieldrin affects the expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 11B

affects expression

Dieldrin affects the expression of CDK11B mRNA

NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:166,212,829...166,238,876

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cyclin-dependent kinase 13

affects expression

Dieldrin affects the expression of CDK13 mRNA

NCBI chr17:47,251,145...47,344,675
Ensembl chr17:47,251,163...47,341,721

G

cyclin dependent kinase 2

affects expression

Dieldrin affects the expression of CDK2 mRNA

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 6

affects expression

Dieldrin affects the expression of CDK6 mRNA

NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase inhibitor 1A

affects expression

Dieldrin affects the expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

affects expression

Dieldrin affects the expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 3

affects expression
increases expression

Dieldrin affects the expression of CDKN3 mRNA
Dieldrin results in increased expression of CDKN3 mRNA

PMID:22546817 PMID:23153324

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CCAAT/enhancer binding protein beta

affects expression

Dieldrin affects the expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

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centromere protein E

increases expression

Dieldrin results in increased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein F

affects expression

Dieldrin affects the expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

craniofacial development protein 1

affects expression

Dieldrin affects the expression of CFDP1 mRNA

NCBI chr19:39,718,313...39,823,824
Ensembl chr19:39,718,347...39,823,824

G

cingulin

decreases expression

Dieldrin results in decreased expression of CGN mRNA

NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645

G

cell growth regulator with ring finger domain 1

affects expression

Dieldrin affects the expression of CGRRF1 mRNA

NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037

G

chromodomain helicase DNA binding protein 7

affects methylation

Dieldrin affects the methylation of CHD7 gene

NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358

G

checkpoint kinase 2

affects expression

Dieldrin affects the expression of CHEK2 mRNA

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

chromogranin B

decreases expression

Dieldrin results in decreased expression of CHGB mRNA

NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166

G

cholinergic receptor, muscarinic 1

decreases expression

Dieldrin results in decreased expression of CHRM1 mRNA

NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356

G

cholinergic receptor, muscarinic 2

affects expression

Dieldrin affects the expression of CHRM2 mRNA

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

cholinergic receptor, muscarinic 4

affects expression

Dieldrin affects the expression of CHRM4 mRNA

NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159

G

cholinergic receptor, muscarinic 5

increases expression

Dieldrin results in increased expression of CHRM5 mRNA

NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252

G

cholinergic receptor nicotinic alpha 1 subunit

decreases expression

Dieldrin results in decreased expression of CHRNA1 mRNA

NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840

G

cholinergic receptor nicotinic alpha 10 subunit

affects methylation

Dieldrin affects the methylation of CHRNA10 gene

NCBI chr 1:156,487,279...156,494,277
Ensembl chr 1:156,487,279...156,491,476

G

cholinergic receptor nicotinic alpha 2 subunit

decreases expression

Dieldrin results in decreased expression of CHRNA2 mRNA

NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601

G

cholinergic receptor nicotinic alpha 3 subunit

decreases expression

Dieldrin results in decreased expression of CHRNA3 mRNA

NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165

G

cholinergic receptor nicotinic alpha 4 subunit

affects expression

Dieldrin affects the expression of CHRNA4 mRNA

NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957

G

cholinergic receptor nicotinic alpha 5 subunit

decreases expression

Dieldrin results in decreased expression of CHRNA5 mRNA

NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146

G

cholinergic receptor nicotinic alpha 7 subunit

increases expression

Dieldrin results in increased expression of CHRNA7 mRNA

NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240

G

cholinergic receptor nicotinic beta 4 subunit

decreases expression

Dieldrin results in decreased expression of CHRNB4 mRNA

NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027

G

cell death-inducing DFFA-like effector a

affects expression

Dieldrin affects the expression of CIDEA mRNA

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

citron rho-interacting serine/threonine kinase

affects expression

Dieldrin affects the expression of CIT mRNA

NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860

G

claudin 2

decreases expression

Dieldrin results in decreased expression of CLDN2 mRNA

NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838

G

CDC-like kinase 1

affects expression

Dieldrin affects the expression of CLK1 mRNA

NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000

G

collagen type XVIII alpha 1 chain

affects expression

Dieldrin affects the expression of COL18A1 mRNA

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

catechol-O-methyltransferase

increases expression

Dieldrin results in increased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

cortistatin

affects expression

Dieldrin affects the expression of CORT mRNA

NCBI chr 5:159,560,591...159,562,032

G

cAMP responsive element binding protein 1

increases phosphorylation

Dieldrin results in increased phosphorylation of CREB1 protein

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

corticotropin releasing hormone

increases expression

Dieldrin results in increased expression of CRH mRNA

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

G

CRK proto-oncogene, adaptor protein

affects expression

Dieldrin affects the expression of CRK mRNA

NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406

G

chromosome segregation 1 like

affects expression

Dieldrin affects the expression of CSE1L mRNA

NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865

G

casein kinase 1, delta

affects expression

Dieldrin affects the expression of CSNK1D mRNA

NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614

G

casein kinase 2 alpha 1

decreases response to substance

CSNK2A1 gene mutant form results in decreased susceptibility to Dieldrin

NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696

G

cysteine and serine rich nuclear protein 1

increases expression

Dieldrin results in increased expression of CSRNP1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cystatin B

affects expression

Dieldrin affects the expression of CSTB mRNA

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

CCCTC-binding factor

affects expression

Dieldrin affects the expression of CTCF mRNA

NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123

G

cullin 1

affects expression

Dieldrin affects the expression of CUL1 mRNA

NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980

G

cullin 2

affects expression

Dieldrin affects the expression of CUL2 mRNA

NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968

G

cullin 5

affects expression

Dieldrin affects the expression of CUL5 mRNA

NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666

G

cullin 7

affects methylation

Dieldrin affects the methylation of CUL7 gene

NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741

G

CWF19 like cell cycle control factor 1

affects expression

Dieldrin affects the expression of CWF19L1 mRNA

NCBI chr 1:242,997,720...243,020,989
Ensembl chr 1:242,997,726...243,020,961

G

CWF19 like cell cycle control factor 2

affects expression

Dieldrin affects the expression of CWF19L2 mRNA

NCBI chr 6:290,148...356,636
Ensembl chr 6:281,685...356,604

G

cytochrome c, somatic

multiple interactions
affects localization

manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Dieldrin affects the localization of CYCS protein]

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

Dieldrin results in increased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression

Dieldrin results in increased expression of CYP1A2 mRNA

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

Dieldrin results in increased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions
increases expression

AGN 193109 inhibits the reaction [Dieldrin results in increased expression of CYP26A1 mRNA]

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression
multiple interactions

Dieldrin results in increased expression of CYP2B6 protein
Dieldrin results in increased expression of CYP2B10 mRNA
NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP2B10 mRNA]

PMID:12049174 PMID:15548381 PMID:32435917

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression
multiple interactions

Dieldrin results in increased expression of CYP3A4 protein
[DDT co-treated with Dieldrin] results in increased expression of CYP3A4 mRNA; Dieldrin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]

PMID:12417264 PMID:15548381 PMID:25028461

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily f, polypeptide 39

affects methylation

Dieldrin affects the methylation of CYP4F39 gene

NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

Dieldrin results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

defender against cell death 1

affects expression

Dieldrin affects the expression of DAD1 mRNA

NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347

G

death-associated protein

affects expression

Dieldrin affects the expression of DAP mRNA

NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752

G

death associated protein 3

affects expression

Dieldrin affects the expression of DAP3 mRNA

NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461

G

death-domain associated protein

affects expression

Dieldrin affects the expression of DAXX mRNA

NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843

G

dopamine beta-hydroxylase

decreases expression

Dieldrin results in decreased expression of DBH mRNA

NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248

G

doublecortin-like kinase 2

affects methylation

Dieldrin affects the methylation of DCLK2 gene

NCBI chr 2:172,202,733...172,338,411
Ensembl chr 2:172,208,706...172,338,250

G

DNA-damage inducible transcript 3

affects expression
increases expression

Dieldrin affects the expression of DDIT3 mRNA
Dieldrin results in increased expression of DDIT3 mRNA

PMID:22546817 PMID:28844784 PMID:31068361

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

affects expression

Dieldrin affects the expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

death effector domain-containing

affects expression

Dieldrin affects the expression of DEDD mRNA

NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332

G

DEP domain containing 5, GATOR1 subcomplex subunit

increases response to substance

DEPDC5 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794

G

diacylglycerol O-acyltransferase 2

decreases expression

Dieldrin results in decreased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

DEAH-box helicase 16

affects expression

Dieldrin affects the expression of DHX16 mRNA

NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948

G

diablo, IAP-binding mitochondrial protein

affects expression

Dieldrin affects the expression of DIABLO mRNA

NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387

G

discs large MAGUK scaffold protein 2

affects methylation

Dieldrin affects the methylation of DLG2 gene

NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475

G

discs large MAGUK scaffold protein 5

affects expression

Dieldrin affects the expression of DLG5 mRNA

NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837

G

DLG associated protein 1

affects methylation

Dieldrin affects the methylation of DLGAP1 gene

NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817

G

DLG associated protein 5

affects expression

Dieldrin affects the expression of DLGAP5 mRNA

NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518

G

dematin actin binding protein

affects methylation

Dieldrin affects the methylation of DMTN gene

NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

Dieldrin results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B9

affects expression

Dieldrin affects the expression of DNAJB9 mRNA

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

deoxyribonuclease 1L3

affects expression

Dieldrin affects the expression of DNASE1L3 mRNA

NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317

G

deoxyribonuclease 2, lysosomal

affects expression

Dieldrin affects the expression of DNASE2 mRNA

NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376

G

DNA methyltransferase 3 alpha

affects methylation

Dieldrin affects the methylation of DNMT3A gene

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

dopamine receptor D3

increases expression

Dieldrin results in increased expression of DRD3 mRNA

NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596

G

dopamine receptor D4

decreases expression

Dieldrin results in decreased expression of DRD4 mRNA

NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553

G

dystonin

affects expression

Dieldrin affects the expression of DST mRNA

NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615

G

deoxythymidylate kinase

affects expression

Dieldrin affects the expression of DTYMK mRNA

NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870

G

dual specificity phosphatase 1

affects expression
increases expression

Dieldrin affects the expression of DUSP1 mRNA
Dieldrin results in increased expression of DUSP1 mRNA

PMID:22546817 PMID:31068361

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 2

increases expression

Dieldrin results in increased expression of DUSP2 mRNA

NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499

G

dual specificity phosphatase 22

affects expression

Dieldrin affects the expression of DUSP22 mRNA

NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321

G

E2F transcription factor 1

affects expression
increases expression

Dieldrin affects the expression of E2F1 mRNA
Dieldrin results in increased expression of E2F1 mRNA

PMID:22546817 PMID:23153324

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 5

affects expression

Dieldrin affects the expression of E2F5 mRNA

NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990

G

E2F transcription factor 8

increases expression

Dieldrin results in increased expression of E2F8 mRNA

NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098

G

estrogen receptor binding site associated antigen 9

affects expression

Dieldrin affects the expression of EBAG9 mRNA

NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248

G

epithelial cell transforming 2

increases expression

Dieldrin results in increased expression of ECT2 mRNA

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

G

EEF1A lysine methyltransferase 3

affects methylation

Dieldrin affects the methylation of EEF1AKMT3 gene

NCBI chr 7:62,853,304...62,864,558
Ensembl chr 7:62,854,899...62,864,617

G

ephrin A2

affects methylation

Dieldrin affects the methylation of EFNA2 gene

NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061

G

epidermal growth factor receptor

affects expression

Dieldrin affects the expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

egl-9 family hypoxia-inducible factor 3

affects expression

Dieldrin affects the expression of EGLN3 mRNA

NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766

G

early growth response 1

increases expression

Dieldrin results in increased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 2

increases expression

Dieldrin results in increased expression of EGR2 mRNA

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

EH domain binding protein 1-like 1

decreases expression

Dieldrin results in decreased expression of EHBP1L1 mRNA

NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270

G

eukaryotic translation initiation factor 2 alpha kinase 4

increases response to substance

EIF2AK4 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630

G

eukaryotic translation initiation factor 4A1

decreases expression

Dieldrin results in decreased expression of EIF4A1 mRNA

NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858

G

elastase, neutrophil expressed

affects methylation

Dieldrin affects the methylation of ELANE gene

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

G

ETS transcription factor ELK1

affects expression

Dieldrin affects the expression of ELK1 mRNA

NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713

G

ELOVL fatty acid elongase 7

increases expression

Dieldrin results in increased expression of ELOVL7 mRNA

NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845

G

Eph receptor A3

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA

NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900

G

Eph receptor A8

multiple interactions
affects methylation

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA
Dieldrin affects the methylation of EPHA8 gene

PMID:28263720 PMID:38995845

NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399

G

Eph receptor B2

affects methylation

Dieldrin affects the methylation of EPHB2 gene

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

G

epoxide hydrolase 1

multiple interactions

Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide]

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

epoxide hydrolase 2

multiple interactions

Dieldrin promotes the reaction [EPHX2 protein results in increased metabolism of stilbene oxide]

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

Era-like 12S mitochondrial rRNA chaperone 1

affects expression

Dieldrin affects the expression of ERAL1 mRNA

NCBI chr10:62,961,725...62,968,747
Ensembl chr10:62,961,730...62,968,994

G

erb-b2 receptor tyrosine kinase 3

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

Ets2 repressor factor

affects expression

Dieldrin affects the expression of ERF mRNA

NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388

G

extra spindle pole bodies like 1, separase

affects expression

Dieldrin affects the expression of ESPL1 mRNA

NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984

G

estrogen receptor 1

multiple interactions
increases expression
increases activity
decreases expression
affects binding

[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; [Dieldrin co-treated with Chlordan] inhibits the reaction [Estradiol binds to ESR1 protein]; [o,p'-DDT co-treated with Methoxychlor co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Toxaphene co-treated with Dieldrin co-treated with Chlordan] inhibits the reaction [Estradiol binds to ESR1 protein]; Dieldrin binds to and results in increased activity of ESR1 protein; Dieldrin inhibits the reaction [Estradiol binds to ESR1 protein]; Dieldrin inhibits the reaction [Estradiol results in decreased expression of ESR1 mRNA]
Dieldrin results in increased expression of ESR1 mRNA
Dieldrin results in increased activity of ESR1 protein
Dieldrin results in decreased expression of ESR1 protein
Dieldrin binds to ESR1 protein

PMID:9168004 PMID:10774817 PMID:11922773 PMID:14579009 PMID:15064155 More...

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

Dieldrin binds to and results in decreased activity of ESR2 protein; Dieldrin promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]
Dieldrin inhibits the reaction [Estradiol binds to ESR2 protein]

PMID:15261991 PMID:16626760 PMID:21278053

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

extended synaptotagmin 1

decreases expression

Dieldrin results in decreased expression of ESYT1 mRNA

NCBI chr 7:928,848...946,199
Ensembl chr 7:928,848...946,199

G

Fas associated via death domain

affects expression

Dieldrin affects the expression of FADD mRNA

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

G

Fas associated factor 1

affects expression

Dieldrin affects the expression of FAF1 mRNA

NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977

G

Fas apoptotic inhibitory molecule 2

affects expression

Dieldrin affects the expression of FAIM2 mRNA

NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168

G

F-box protein 2

affects expression

Dieldrin affects the expression of FBXO2 mRNA

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

G

F-box and WD repeat domain containing 11

increases response to substance

FBXW11 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr10:17,232,735...17,330,574
Ensembl chr10:17,227,181...17,330,571

G

fem-1 homolog B

affects expression

Dieldrin affects the expression of FEM1B mRNA

NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577

G

fibroblast growth factor 1

affects expression

Dieldrin affects the expression of FGF1 mRNA

PMID:19130878 PMID:22546817

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fibroblast growth factor 12

decreases expression

Dieldrin results in decreased expression of FGF12 mRNA

NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607

G

fibroblast growth factor 17

decreases expression

Dieldrin results in decreased expression of FGF17 mRNA

NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063

G

fibroblast growth factor 19

affects expression

Dieldrin affects the expression of FGF15 mRNA

NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287

G

fibroblast growth factor 2

decreases expression
affects expression

Dieldrin results in decreased expression of FGF2 mRNA
Dieldrin affects the expression of FGF2 mRNA

PMID:19130878 PMID:22546817

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor 21

decreases expression

Dieldrin results in decreased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor 22

increases expression

Dieldrin results in increased expression of FGF22 mRNA

NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486

G

fibroblast growth factor 8

affects methylation

Dieldrin affects the methylation of FGF8 gene

NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359

G

fibroblast growth factor 9

increases expression
affects expression

Dieldrin results in increased expression of FGF9 mRNA
Dieldrin affects the expression of FGF9 mRNA

PMID:19130878 PMID:22546817

NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309

G

Fibroblast growth factor receptor 1

affects expression

Dieldrin affects the expression of FGFR1 mRNA

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibroblast growth factor receptor 2

affects methylation

Dieldrin affects the methylation of FGFR2 gene

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

fibroblast growth factor receptor 4

affects expression

Dieldrin affects the expression of FGFR4 mRNA

NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242

G

formin homology 2 domain containing 3

affects methylation

Dieldrin affects the methylation of FHOD3 gene

NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796

G

fission, mitochondrial 1

affects expression

Dieldrin affects the expression of FIS1 mRNA

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

fibronectin leucine rich transmembrane protein 1

affects methylation

Dieldrin affects the methylation of FLRT1 gene

NCBI chr 1:204,275,785...204,292,844
Ensembl chr 1:204,275,367...204,353,750

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; BX795 promotes the reaction [Dieldrin results in increased expression of FOS mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]; Wortmannin inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression

Dieldrin results in increased expression of FOSB mRNA

NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465

G

FOS like 2, AP-1 transcription factor subunit

increases expression

Dieldrin results in increased expression of FOSL2 mRNA

NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034

G

forkhead box N3

affects expression

Dieldrin affects the expression of FOXN3 mRNA

NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401

G

forkhead box O3

affects expression
affects methylation

Dieldrin affects the expression of FOXO3 mRNA
Dieldrin affects the methylation of FOXO3 gene

PMID:22546817 PMID:38995845

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

forkhead box P1

affects methylation

Dieldrin affects the methylation of FOXP1 gene

NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258

G

FERM domain containing 4B

affects methylation

Dieldrin affects the methylation of FRMD4B gene

NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197

G

FMR1 autosomal homolog 1

affects expression

Dieldrin affects the expression of FXR1 mRNA

NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590

G

FYN proto-oncogene, Src family tyrosine kinase

increases activity
affects expression
multiple interactions

Dieldrin results in increased activity of FYN protein
Dieldrin affects the expression of FYN mRNA
FYN protein promotes the reaction [Dieldrin promotes the reaction [CASP3 protein results in increased cleavage of and results in increased activity of PRKCD protein]]; FYN protein promotes the reaction [Dieldrin results in increased phosphorylation of PRKCD protein]

PMID:21801747 PMID:22546817

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

G

frizzled class receptor 1

increases expression

Dieldrin results in increased expression of FZD1 mRNA

NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643

G

frizzled class receptor 2

increases expression

Dieldrin results in increased expression of FZD2 mRNA

NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334

G

frizzled class receptor 3

decreases expression

Dieldrin results in decreased expression of FZD3 mRNA

NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369

G

frizzled class receptor 6

affects expression

Dieldrin affects the expression of FZD6 mRNA

NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776

G

frizzled class receptor 7

affects expression

Dieldrin affects the expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

frizzled class receptor 9

decreases expression

Dieldrin results in decreased expression of FZD9 mRNA

NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398

G

fizzy and cell division cycle 20 related 1

affects expression

Dieldrin affects the expression of FZR1 mRNA

NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952

G

glucose-6-phosphate dehydrogenase

affects expression

Dieldrin affects the expression of G6PD mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

gamma-aminobutyric acid type A receptor subunit alpha 1

multiple interactions
decreases expression

Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Dieldrin results in decreased expression of GABRA1 mRNA

PMID:9600394 PMID:14637376

NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864

G

gamma-aminobutyric acid type A receptor subunit alpha 2

multiple interactions

Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

G

gamma-aminobutyric acid type A receptor subunit beta 3

decreases expression
increases expression

Dieldrin results in decreased expression of GABRB3 mRNA
Dieldrin results in increased expression of GABRB3 mRNA

PMID:9302086 PMID:9600394

NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961

G

gamma-aminobutyric acid type A receptor subunit gamma 1

decreases expression

Dieldrin results in decreased expression of GABRG1 mRNA

NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956

G

gamma-aminobutyric acid type A receptor subunit gamma 2

multiple interactions
decreases expression

Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Dieldrin results in decreased expression of GABRG2 mRNA

PMID:9302086 PMID:14637376

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

gamma-aminobutyric acid type A receptor subunit rho 1

affects binding

Dieldrin binds to GABRR1 protein

NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228

G

growth arrest and DNA-damage-inducible, alpha

affects expression

Dieldrin affects the expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, gamma

affects expression

Dieldrin affects the expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

galactose-3-O-sulfotransferase 1

affects methylation

Dieldrin affects the methylation of GAL3ST1 gene

NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388

G

polypeptide N-acetylgalactosaminyltransferase 18

affects methylation

Dieldrin affects the methylation of GALNT18 gene

NCBI chr 1:165,593,180...165,904,268
Ensembl chr 1:165,593,187...165,904,268

G

polypeptide N-acetylgalactosaminyltransferase 2

affects methylation

Dieldrin affects the methylation of GALNT2 gene

NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813

G

polypeptide N-acetylgalactosaminyltransferase 3

increases expression

Dieldrin results in increased expression of GALNT3 mRNA

NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268

G

guanidinoacetate N-methyltransferase

affects methylation

Dieldrin affects the methylation of GAMT gene

NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778

G

growth associated protein 43

multiple interactions

Dieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]

NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045

G

growth differentiation factor 15

affects methylation

Dieldrin affects the methylation of GDF15 gene

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

guided entry of tail-anchored proteins factor 1

decreases expression

Dieldrin results in decreased expression of WRB mRNA

NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973

G

glial fibrillary acidic protein

multiple interactions

Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

growth factor independent 1B transcriptional repressor

affects expression

Dieldrin affects the expression of GFI1B mRNA

NCBI chr 3:11,940,232...11,952,989
Ensembl chr 3:11,940,233...11,952,942

G

GDNF family receptor alpha 1

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA

NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473

G

gap junction protein, alpha 1

multiple interactions
decreases phosphorylation
decreases expression

[Dieldrin co-treated with 2,4,5,2',4',5'-hexabromobiphenyl] results in decreased expression of GJA1 protein; [Dieldrin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GJA1 protein
Dieldrin results in decreased phosphorylation of GJA1 protein
chaetoglobosins inhibits the reaction [Dieldrin results in decreased phosphorylation of GJA1 protein]
Dieldrin results in decreased expression of GJA1 mRNA; Dieldrin results in decreased expression of GJA1 protein; Dieldrin results in decreased expression of GJA1 protein modified form

PMID:8068183 PMID:8820588 PMID:15082077 PMID:18040759

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

gap junction protein, beta 2

decreases expression

Dieldrin results in decreased expression of GJB2 protein

NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177

G

GNAS complex locus

affects methylation

Dieldrin affects the methylation of GNAS gene

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

gonadotropin releasing hormone 1

affects expression

Dieldrin affects the expression of GNRH1 mRNA

NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581

G

glycoprotein Ib platelet subunit beta

affects methylation

Dieldrin affects the methylation of GP1BB gene

NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392

G

glutathione peroxidase 1

decreases expression
affects expression
multiple interactions

Dieldrin results in decreased expression of GPX1 mRNA
Dieldrin affects the expression of GPX1 mRNA
GPX1 protein results in decreased activity of and results in decreased susceptibility to Dieldrin

PMID:12621067 PMID:19440498 PMID:22546817

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 3

increases expression

Dieldrin results in increased expression of GPX3 mRNA

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 4

increases expression

Dieldrin results in increased expression of GPX4 mRNA

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

glutathione peroxidase 6

decreases expression

Dieldrin results in decreased expression of GPX6 mRNA

NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091

G

GRAM domain containing 1C

affects methylation

Dieldrin affects the methylation of GRAMD1C gene

NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570

G

growth factor receptor bound protein 10

affects methylation

Dieldrin affects the methylation of GRB10 gene

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

glutamate ionotropic receptor AMPA type subunit 1

increases expression

Dieldrin results in increased expression of GRIA1 mRNA

NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283

G

glutamate ionotropic receptor AMPA type subunit 2

decreases expression

Dieldrin results in decreased expression of GRIA2 mRNA

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

glutamate ionotropic receptor delta type subunit 1

affects expression

Dieldrin affects the expression of GRID1 mRNA

NCBI chr16:10,138,564...10,885,803
Ensembl chr16:10,138,925...10,885,808

G

glutamate ionotropic receptor kainate type subunit 3

decreases expression

Dieldrin results in decreased expression of GRIK3 mRNA

NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307

G

glutamate ionotropic receptor NMDA type subunit 1

increases uptake
increases expression

Dieldrin results in increased uptake of GRIN1 protein
Dieldrin results in increased expression of GRIN1 mRNA

PMID:19440498 PMID:19812363

NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603

G

glutamate ionotropic receptor NMDA type subunit 2B

decreases expression

Dieldrin results in decreased expression of GRIN2B mRNA

NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279

G

glutamate ionotropic receptor NMDA type subunit 2C

affects expression

Dieldrin affects the expression of GRIN2C mRNA

NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427

G

glutamate ionotropic receptor NMDA type subunit 3B

affects expression

Dieldrin affects the expression of GRIN3B mRNA

NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

increases expression

Dieldrin results in increased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

G protein-coupled receptor kinase 2

increases expression

Dieldrin results in increased expression of GRK2 mRNA

NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582

G

glutamate metabotropic receptor 5

decreases expression

Dieldrin results in decreased expression of GRM5 protein

NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274

G

glutathione S-transferase alpha 5

affects expression
increases expression

Dieldrin affects the expression of GSTA5 mRNA
Dieldrin results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 4

affects expression

Dieldrin affects the expression of GSTM4 mRNA

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

affects expression

Dieldrin affects the expression of GSTM3 mRNA

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase omega 1

increases expression

Dieldrin results in increased expression of GSTO1 mRNA

NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468

G

glutathione S-transferase omega 2

affects expression

Dieldrin affects the expression of GSTO2 mRNA

NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866

G

H2A clustered histone 25

increases expression

Dieldrin results in increased expression of H2AC25 mRNA

NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874

G

H2A clustered histone 4

increases expression

Dieldrin results in increased expression of HIST1H2AC mRNA

NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381

G

H2A.Z variant histone 1

increases expression

Dieldrin results in increased expression of H2AZ1 mRNA

NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485

G

HAUS augmin-like complex, subunit 1

affects expression

Dieldrin affects the expression of HAUS1 mRNA

NCBI chr18:71,275,417...71,286,626
Ensembl chr18:71,273,537...71,286,660

G

histone deacetylase 9

affects methylation

Dieldrin affects the methylation of HDAC9 gene

NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333

G

heart development protein with EGF-like domains 1

affects methylation

Dieldrin affects the methylation of HEG1 gene

NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051

G

3-hydroxyisobutyrate dehydrogenase

decreases expression

Dieldrin results in decreased expression of HIBADH mRNA

NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617

G

homeodomain interacting protein kinase 1

affects expression

Dieldrin affects the expression of HIPK1 mRNA

NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902

G

hexokinase 2

increases expression

Dieldrin results in increased expression of HK2 mRNA

NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530

G

heme oxygenase 1

multiple interactions
affects expression
increases expression

Dieldrin results in increased expression of and results in increased activity of HMOX1 protein; SB 203580 inhibits the reaction [Dieldrin results in increased expression of HMOX1 protein]
Dieldrin affects the expression of HMOX1 mRNA
Dieldrin results in increased expression of HMOX1 mRNA

PMID:11181820 PMID:15770161 PMID:22546817

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

homeobox A2

affects methylation

Dieldrin affects the methylation of HOXA2 gene

NCBI chr 4:81,262,668...81,266,970
Ensembl chr 4:81,262,768...81,265,044

G

homeobox A3

affects methylation

Dieldrin affects the methylation of HOXA3 gene

NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218

G

homeo box A4

affects methylation

Dieldrin affects the methylation of HOXA4 gene

NCBI chr 4:81,289,677...81,291,685
Ensembl chr 4:81,289,682...81,291,685

G

homeobox A6

affects methylation

Dieldrin affects the methylation of HOXA6 gene

NCBI chr 4:81,304,918...81,313,184
Ensembl chr 4:81,306,407...81,308,850

G

harakiri, BCL2 interacting protein

affects expression

Dieldrin affects the expression of HRK mRNA

NCBI chr12:38,387,484...38,409,652

G

heat shock protein family A (Hsp70) member 1A

affects expression

Dieldrin affects the expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

Dieldrin results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

Dieldrin results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

heat shock protein family A (Hsp70) member 9

affects expression

Dieldrin affects the expression of HSPA9 mRNA

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

G

5-hydroxytryptamine receptor 1A

decreases expression

Dieldrin results in decreased expression of HTR1A mRNA

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 1D

affects expression

Dieldrin affects the expression of HTR1D mRNA

NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619

G

5-hydroxytryptamine receptor 2B

affects expression

Dieldrin affects the expression of HTR2B mRNA

NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108

G

5-hydroxytryptamine receptor 2C

affects expression

Dieldrin affects the expression of HTR2C mRNA

NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287

G

5-hydroxytryptamine receptor 3A

decreases expression

Dieldrin results in decreased expression of HTR3A mRNA

NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389

G

5-hydroxytryptamine receptor 3B

decreases expression

Dieldrin results in decreased expression of HTR3B mRNA

NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:49,279,173...49,308,444

G

5-hydroxytryptamine receptor 5A

increases expression

Dieldrin results in increased expression of HTR5A mRNA

NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651

G

5-hydroxytryptamine (serotonin) receptor 5B

decreases expression

Dieldrin results in decreased expression of HTR5B mRNA

NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835

G

5-hydroxytryptamine receptor 6

affects expression

Dieldrin affects the expression of HTR6 mRNA

NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912

G

inducible T-cell co-stimulator

increases expression

Dieldrin results in increased expression of ICOS mRNA

NCBI chr 9:62,368,075...62,406,900
Ensembl chr 9:62,383,832...62,405,672

G

inhibitor of DNA binding 2

affects expression

Dieldrin affects the expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

affects expression

Dieldrin affects the expression of IDH3B mRNA

NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982

G

immediate early response 2

increases expression

Dieldrin results in increased expression of IER2 mRNA

NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211

G

immediate early response 3

increases expression

Dieldrin results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon-induced protein 35

decreases expression

Dieldrin results in decreased expression of IFI35 mRNA

NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952

G

interferon-induced protein 44

decreases expression

Dieldrin results in decreased expression of IFI44 mRNA

NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844

G

interferon induced with helicase C domain 1

decreases expression

Dieldrin results in decreased expression of IFIH1 mRNA

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

interferon-induced protein with tetratricopeptide repeats 2

decreases expression
multiple interactions

Dieldrin results in decreased expression of IFIT2 mRNA
Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]

NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635

G

interferon-induced protein with tetratricopeptide repeats 3

decreases expression

Dieldrin results in decreased expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

interferon induced transmembrane protein 1

affects expression

Dieldrin affects the expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

interferon induced transmembrane protein 3

decreases expression

Dieldrin results in decreased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

insulin-like growth factor 1

affects expression

Dieldrin affects the expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

interleukin 10

affects expression

Dieldrin affects the expression of IL10 mRNA

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 13

affects methylation

Dieldrin affects the methylation of IL13 gene

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 18

affects expression

Dieldrin affects the expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

increases expression

Dieldrin results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

increases expression

Dieldrin results in increased expression of IL2 mRNA

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 6

increases expression

Dieldrin results in increased expression of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inositol polyphosphate-5-phosphatase D

affects expression

Dieldrin affects the expression of INPP5D mRNA

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

inositol polyphosphate-5-phosphatase F

affects methylation

Dieldrin affects the methylation of INPP5F gene

NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276

G

insulin induced gene 2

decreases expression

Dieldrin results in decreased expression of INSIG2 mRNA

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

G

interleukin-1 receptor-associated kinase 3

affects expression

Dieldrin affects the expression of IRAK3 mRNA

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

G

interferon regulatory factor 7

decreases expression

Dieldrin results in decreased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

interferon regulatory factor 9

decreases expression

Dieldrin results in decreased expression of IRF9 mRNA

NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236

G

immunity-related GTPase M

decreases expression

Dieldrin results in decreased expression of IRGM mRNA

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

ISG15 ubiquitin-like modifier

affects expression
decreases expression

Dieldrin affects the expression of ISG15 mRNA
Dieldrin results in decreased expression of ISG15 mRNA

PMID:22546817 PMID:34051100

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

G

interferon stimulated exonuclease gene 20

decreases expression

Dieldrin results in decreased expression of ISG20 mRNA

NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027

G

integral membrane protein 2B

affects expression

Dieldrin affects the expression of ITM2B mRNA

NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917

G

intersectin 1

affects methylation

Dieldrin affects the methylation of ITSN1 gene

NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645

G

Janus kinase 2

decreases expression

Dieldrin results in decreased expression of JAK2 mRNA

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

affects expression

Dieldrin affects the expression of JMJD6 mRNA

NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases phosphorylation
increases expression
decreases response to substance
affects expression

Dieldrin results in increased phosphorylation of JUN protein
Dieldrin results in increased expression of JUN mRNA
JUN gene mutant form results in decreased susceptibility to Dieldrin
Dieldrin affects the expression of JUN mRNA

PMID:15888667 PMID:22546817 PMID:31068361 PMID:32421776

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

affects expression
increases expression

Dieldrin affects the expression of JUNB mRNA
Dieldrin results in increased expression of JUNB mRNA

PMID:22546817 PMID:31068361

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

JunD proto-oncogene, AP-1 transcription factor subunit

affects expression
increases expression

Dieldrin affects the expression of JUND mRNA
Dieldrin results in increased expression of JUND mRNA

PMID:22546817 PMID:31068361

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

katanin catalytic subunit A1

affects expression

Dieldrin affects the expression of KATNA1 mRNA

NCBI chr 1:2,202,501...2,244,132
Ensembl chr 1:2,202,490...2,244,131

G

potassium inwardly-rectifying channel, subfamily J, member 10

affects methylation

Dieldrin affects the methylation of KCNJ10 gene

NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461

G

kinesin family member 18B

increases expression

Dieldrin results in increased expression of KIF18B mRNA

NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850

G

kinesin family member 20B

affects expression

Dieldrin affects the expression of KIF20B mRNA

NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787

G

KIT proto-oncogene receptor tyrosine kinase

multiple interactions

[Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA

PMID:19422813 PMID:28263720

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

KLF transcription factor 10

affects expression

Dieldrin affects the expression of KLF10 mRNA

NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 4

increases expression

Dieldrin results in increased expression of KLF4 mRNA

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

KLF transcription factor 6

increases expression

Dieldrin results in increased expression of KLF6 mRNA

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

KLF transcription factor 9

decreases expression

Dieldrin results in decreased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

kelch-like family, member 42

decreases response to substance

KLHL42 gene mutant form results in decreased susceptibility to Dieldrin

NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283

G

kallikrein 1-related peptidase B3

increases expression

Dieldrin results in increased expression of KLK1B3 mRNA

NCBI chr 1:94,709,105...94,713,308
Ensembl chr 1:94,709,105...94,713,308

G

laminin subunit beta 1

increases expression

Dieldrin results in increased expression of LAMB1 mRNA

NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585

G

lymphocyte transmembrane adaptor 1

increases expression

Dieldrin results in increased expression of LAX1 mRNA

NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381

G

lipocalin 2

affects expression

Dieldrin affects the expression of LCN2 mRNA

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

low density lipoprotein receptor

increases expression

Dieldrin results in increased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

galectin 12

affects expression

Dieldrin affects the expression of LGALS12 mRNA

NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759

G

galectin 7

affects expression

Dieldrin affects the expression of LGALS7 mRNA

NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015

G

leucine-rich, glioma inactivated 1

affects expression

Dieldrin affects the expression of LGI1 mRNA

NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616

G

lipopolysaccharide-induced TNF factor

affects expression

Dieldrin affects the expression of LITAF mRNA

NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763

G

LMBR1 domain containing 1

decreases expression

Dieldrin results in decreased expression of LMBRD1 mRNA

NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:27,096,297...27,178,090

G

lamin A/C

affects methylation

Dieldrin affects the methylation of LMNA gene

NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423

G

lamin B1

increases expression

Dieldrin results in increased expression of LMNB1 mRNA

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

LIM homeobox transcription factor 1 beta

affects methylation

Dieldrin affects the methylation of LMX1B gene

PMID:30859219 PMID:38995845

NCBI chr 3:16,862,195...16,940,899
Ensembl chr 3:16,862,195...16,940,899

G

LDL receptor related protein 8

affects methylation

Dieldrin affects the methylation of LRP8 gene

NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352

G

leucine rich repeat containing 1

increases expression

Dieldrin results in increased expression of LRRC1 mRNA

NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:78,239,900...78,406,490

G

leucine rich repeat containing 2

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA

NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185

G

leucine rich repeat containing 4B

affects methylation

Dieldrin affects the methylation of LRRC4B gene

NCBI chr 1:94,922,034...94,956,309
Ensembl chr 1:94,935,603...94,956,263

G

lymphocyte-specific protein 1

affects expression

Dieldrin affects the expression of LSP1 mRNA

NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416

G

mono-ADP ribosylhydrolase 1

affects methylation

Dieldrin affects the methylation of MACROD1 gene

NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716

G

MAF bZIP transcription factor K

affects expression

Dieldrin affects the expression of MAFK mRNA

NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048

G

MAGE family member H1

affects expression

Dieldrin affects the expression of MAGEH1 mRNA

NCBI chr X:18,350,015...18,351,271
Ensembl chr X:18,349,774...18,351,516

G

microtubule-associated protein 2

multiple interactions

Dieldrin promotes the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in increased expression of MAP2 mRNA]

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

mitogen activated protein kinase kinase 1

multiple interactions

Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K1 protein

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

multiple interactions
affects methylation

Dieldrin results in increased phosphorylation of and results in increased activity of MAP2K2 protein
Dieldrin affects the methylation of MAP2K2 gene

PMID:15888667 PMID:38995845

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase kinase kinase 10

affects expression

Dieldrin affects the expression of MAP3K10 mRNA

NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:82,955,207...82,974,084

G

mitogen-activated protein kinase kinase kinase 14

increases expression

Dieldrin results in increased expression of MAP3K14 mRNA

NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523

G

mitogen-activated protein kinase kinase kinase 5

affects methylation

Dieldrin affects the methylation of MAP3K5 gene

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen-activated protein kinase kinase kinase 6

affects expression

Dieldrin affects the expression of MAP3K6 mRNA

NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK1 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]
Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK1 protein]
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein]

PMID:15531431 PMID:15888667 PMID:17174995 PMID:18040759 PMID:21278053 More...

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen-activated protein kinase 12

affects expression

Dieldrin affects the expression of MAPK12 mRNA

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

G

mitogen activated protein kinase 13

affects expression

Dieldrin affects the expression of MAPK13 mRNA

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

G

mitogen activated protein kinase 14

affects methylation

Dieldrin affects the methylation of MAPK14 gene

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

mitogen activated protein kinase 3

multiple interactions
affects expression
increases phosphorylation

calphostin C inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; Dieldrin results in increased phosphorylation of and results in increased activity of MAPK3 protein; geldanamycin inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]
Dieldrin promotes the reaction [[Colforsin co-treated with Rolipram co-treated with Picrotoxin] results in increased phosphorylation of MAPK3 protein]
Dieldrin affects the expression of MAPK3 mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline co-treated with 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole co-treated with 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]; [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein]

PMID:15531431 PMID:15888667 PMID:18040759 PMID:21278053 PMID:22546817 More...

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8 interacting protein 1

affects expression

Dieldrin affects the expression of MAPK8IP1 mRNA

NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884

G

MCL1 apoptosis regulator, BCL2 family member

increases expression

Dieldrin results in increased expression of MCL1 mRNA

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

G

mucolipin TRP cation channel 2

affects response to substance

MCOLN2 gene SNP affects the susceptibility to Dieldrin

NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702

G

microspherule protein 1

affects expression

Dieldrin affects the expression of MCRS1 mRNA

NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685

G

mediator of DNA damage checkpoint 1

affects expression

Dieldrin affects the expression of MDC1 mRNA

NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240

G

midkine

affects expression

Dieldrin affects the expression of MDK mRNA

NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130

G

MDM2 proto-oncogene

affects expression
affects methylation

Dieldrin affects the expression of MDM2 mRNA
Dieldrin affects the methylation of MDM2 gene

PMID:22546817 PMID:38995845

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

MDM4 regulator of p53

affects expression

Dieldrin affects the expression of MDM4 mRNA

NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226

G

menin 1

affects expression

Dieldrin affects the expression of MEN1 mRNA

NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871

G

MER proto-oncogene, tyrosine kinase

multiple interactions

[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA

NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554

G

monoglyceride lipase

affects methylation

Dieldrin affects the methylation of MGLL gene

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

microsomal glutathione S-transferase 2

decreases expression

Dieldrin results in decreased expression of MGST2 mRNA

NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828

G

microRNA 24-2

increases expression

Dieldrin results in increased expression of MIR24-2 mRNA

NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790

G

marker of proliferation Ki-67

affects expression

Dieldrin affects the expression of MKI67 mRNA

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

monocyte to macrophage differentiation-associated

increases expression

Dieldrin results in increased expression of MMD mRNA

NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528

G

matrix metallopeptidase 9

increases expression

Dieldrin results in increased expression of MMP9 mRNA

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

modulator of apoptosis 1

affects expression

Dieldrin affects the expression of MOAP1 mRNA

NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643

G

myocardin related transcription factor A

affects expression

Dieldrin affects the expression of MRTFA mRNA

NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418

G

mutS homolog 2

affects expression

Dieldrin affects the expression of MSH2 mRNA

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

G

mitochondrial carrier 1

affects expression

Dieldrin affects the expression of MTCH1 mRNA

NCBI chr20:7,389,942...7,413,426
Ensembl chr20:7,389,949...7,413,426

G

mechanistic target of rapamycin kinase

increases phosphorylation

Dieldrin results in increased phosphorylation of MTOR protein

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

MX dynamin like GTPase 1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]
Dieldrin results in decreased expression of MX1 mRNA

NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507

G

MX dynamin like GTPase 2

decreases expression

Dieldrin results in decreased expression of MX2 mRNA

NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342

G

myeloid-associated differentiation marker

increases expression

Dieldrin results in increased expression of MYADM mRNA

NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035

G

MYC proto-oncogene, bHLH transcription factor

affects expression

Dieldrin affects the expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

MYCN proto-oncogene, bHLH transcription factor

affects expression

Dieldrin affects the expression of MYCN mRNA

NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590

G

myogenic factor 6

affects methylation

Dieldrin affects the methylation of MYF6 gene

NCBI chr 7:42,813,008...42,814,852
Ensembl chr 7:42,812,792...42,814,852

G

myosin IIIB

affects methylation

Dieldrin affects the methylation of MYO3B gene

NCBI chr 3:54,820,225...55,228,518
Ensembl chr 3:54,820,251...55,227,373

G

nucleus accumbens associated 1

affects expression

Dieldrin affects the expression of NACC1 mRNA

NCBI chr19:23,468,688...23,486,528
Ensembl chr19:23,468,419...23,486,528

G

N-acetylglutamate synthase

decreases expression

Dieldrin results in decreased expression of NAGS mRNA

NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465

G

nicotinamide phosphoribosyltransferase

affects expression

Dieldrin affects the expression of NAMPT mRNA

NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100

G

Nanog homeobox

multiple interactions

Dieldrin inhibits the reaction [[4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with LDN 193189] results in decreased expression of NANOG mRNA]

NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116

G

NDC80 kinetochore complex component

affects expression

Dieldrin affects the expression of NDC80 mRNA

NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924

G

necdin, MAGE family member

affects expression

Dieldrin affects the expression of NDN mRNA

NCBI chr 1:115,849,168...115,850,767
Ensembl chr 1:115,849,105...115,850,767

G

nectin cell adhesion molecule 1

affects methylation

Dieldrin affects the methylation of NECTIN1 gene

NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787

G

NEDD8 ubiquitin like modifier

affects expression

Dieldrin affects the expression of NEDD8 mRNA

NCBI chr15:29,153,556...29,165,575
Ensembl chr15:29,153,556...29,166,160

G

neurofilament heavy chain

decreases expression

Dieldrin results in decreased expression of NEFH mRNA

NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351

G

neurofilament light chain

increases expression

Dieldrin results in increased expression of NEFL mRNA

NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793

G

neurofilament medium chain

increases expression

Dieldrin results in increased expression of NEFM mRNA

NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755

G

NIMA-related kinase 3

affects expression

Dieldrin affects the expression of NEK3 mRNA

NCBI chr16:69,867,020...69,892,477
Ensembl chr16:69,867,047...69,892,508

G

nuclear factor of activated T-cells 2

decreases phosphorylation

Dieldrin results in decreased phosphorylation of NFATC2 protein

NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325

G

nuclear factor kappa B subunit 1

affects expression

Dieldrin affects the expression of NFKB1 mRNA

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

increases expression

Dieldrin results in increased expression of NFKBIA mRNA

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor delta

increases expression

Dieldrin results in increased expression of NFKBID mRNA

NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447

G

NFKB inhibitor zeta

increases expression

Dieldrin results in increased expression of NFKBIZ mRNA

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

G

NFU1 iron-sulfur cluster scaffold

affects expression

Dieldrin affects the expression of NFU1 mRNA

NCBI chr 4:119,458,981...119,480,162
Ensembl chr 4:119,459,061...119,480,373

G

nuclear transcription factor Y subunit gamma

affects expression

Dieldrin affects the expression of NFYC mRNA

NCBI chr 5:134,336,802...134,405,372
Ensembl chr 5:134,336,808...134,405,377

G

nerve growth factor

multiple interactions

[Dieldrin co-treated with NGF protein] results in increased expression of SLC1A5 mRNA; [Dieldrin co-treated with NGF protein] results in increased expression of SLC7A11 mRNA
Dieldrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]

PMID:20600679 PMID:28385489

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

nicotinamide nucleotide transhydrogenase

decreases expression

Dieldrin results in decreased expression of NNT mRNA

NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823

G

NOP2 nucleolar protein

affects expression

Dieldrin affects the expression of NOP2 mRNA

NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459

G

notch receptor 1

affects expression

Dieldrin affects the expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

notch receptor 2

affects expression
decreases expression

Dieldrin affects the expression of NOTCH2 mRNA
Dieldrin results in decreased expression of NOTCH2 mRNA

PMID:22546817 PMID:31068361

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

notch receptor 3

decreases expression

Dieldrin results in decreased expression of NOTCH3 mRNA

NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025

G

NADPH oxidase 1

multiple interactions

[Hexachlorocyclohexane co-treated with Dieldrin] results in decreased expression of NOX1 protein

NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236

G

neuronal PAS domain protein 4

increases expression

Dieldrin results in increased expression of NPAS4 mRNA

NCBI chr 1:202,281,260...202,298,681
Ensembl chr 1:202,281,958...202,286,724

G

nucleophosmin 1

affects expression

Dieldrin affects the expression of NPM1 mRNA

NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
Ensembl chr X:17,739,941...17,751,645

G

NPR2-like, GATOR1 complex subunit

increases response to substance

NPRL2 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996

G

NPR3-like, GATOR1 complex subunit

increases response to substance

NPRL3 gene mutant form results in increased susceptibility to Dieldrin

NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810

G

neuropeptide Y

increases expression

Dieldrin results in increased expression of NPY mRNA

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

G

nuclear receptor subfamily 1, group I, member 2

increases activity
multiple interactions

Dieldrin results in increased activity of NR1I2 protein
[Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA; [Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA
[DDT co-treated with Dieldrin] results in increased activity of NR1I2 protein; Dieldrin binds to and results in increased activity of NR1I2 protein; Dieldrin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]
Dieldrin binds to and results in increased activity of NR1I2 protein; NR1I2 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA]

PMID:12049174 PMID:12417264 PMID:15548381 PMID:16054614 PMID:21115097 More...

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
increases activity

NR1I3 protein affects the reaction [Dieldrin results in increased expression of AOX1 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Dieldrin results in increased expression of CYP3A11 mRNA]
Dieldrin results in increased activity of NR1I3 protein

PMID:12049174 PMID:28927721 PMID:32435917

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 4, group A, member 1

increases expression

Dieldrin results in increased expression of NR4A1 mRNA

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297