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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:erucifoline
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Accession:CHEBI:136462 term browser browse the term
Definition:A pyrrolizine alkaloid that is produced by several Jacobaea species and displays toxicity towards insect herbivores.
Synonyms:exact_synonym: (5aR,8Z,9aS,10aR,13bR)-8-ethylidene-9a-(hydroxymethyl)-10a-methyl-2,4,5,5a,8,9,9a,10a,13,13b-decahydrooxireno[8,9][1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-7,11-dione
 related_synonym: Formula=C18H23NO6;   InChI=1S/C18H23NO6/c1-3-11-8-18(10-20)17(2,25-18)16(22)23-9-12-4-6-19-7-5-13(14(12)19)24-15(11)21/h3-4,13-14,20H,5-10H2,1-2H3/b11-3-/t13-,14-,17+,18+/m1/s1;   InChIKey=NOQVBHHOUTTZGE-LUZNJDLOSA-N;   SMILES=C/1(\\C[C@]2(O[C@]2(C(=O)OCC3=CCN4CC[C@@H](OC1=O)[C@@]34[H])C)CO)=C/C
 xref: AGR:IND22014228;   CAS:40158-95-0;   Chemspider:57579891
 xref_mesh: MESH:C459639
 xref: PMID:11978435;   PMID:15081286;   PMID:21819407;   PMID:21969251;   PMID:24981118;   PMID:25607464;   PMID:28267991;   PMID:29377789;   Reaxys:5456751


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erucifoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases expression ISO erucifoline results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        pesticide 18478
          insecticide 17106
            erucifoline 1
              acetylerucifoline 0
              acetylerucifoline N-oxide 0
              erucifoline N-oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  organic heteropolycyclic compound 18651
                                    organic heterobicyclic compound 17545
                                      pyrrolizines 835
                                        pyrrolizine alkaloid 634
                                          senecionan 634
                                            erucifoline 1
                                              acetylerucifoline 0
                                              acetylerucifoline N-oxide 0
                                              erucifoline N-oxide 0
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