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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:udenafil
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Accession:CHEBI:135926 term browser browse the term
Synonyms:related_synonym: DA-8159;   Formula=C25H36N6O4S;   InChI=1S/C25H36N6O4S/c1-5-8-20-22-23(31(4)29-20)25(32)28-24(27-22)19-16-18(10-11-21(19)35-15-6-2)36(33,34)26-13-12-17-9-7-14-30(17)3/h10-11,16-17,26H,5-9,12-15H2,1-4H3,(H,27,28,32);   InChIKey=IYFNEFQTYQPVOC-UHFFFAOYSA-N;   SMILES=CCCOC1=CC=C(C=C1C2=NC(=O)C=3N(C)N=C(CCC)C3N2)S(=O)(=O)NCCC4CCCN4C;   zydena
 xref: CAS:268203-93-6;   Drug_Central:4141;   HMDB:HMDB0015628
 xref_mesh: MESH:C419664


show annotations for term's descendants           Sort by:
udenafil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 multiple interactions EXP udenafil inhibits the reaction [Cholesterol, Dietary results in decreased expression of CCND1 mRNA] CTD PMID:17137605 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 multiple interactions EXP udenafil inhibits the reaction [Cholesterol, Dietary results in increased expression of COX6A2 mRNA] CTD PMID:17137605 NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:182,788,528...182,789,274 		JBrowse link
G Ednrb endothelin receptor type B decreases expression EXP udenafil results in decreased expression of EDNRB CTD PMID:21366883 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression EXP udenafil results in decreased expression of HIF1A CTD PMID:21366883 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Klf5 KLF transcription factor 5 multiple interactions EXP udenafil inhibits the reaction [Cholesterol, Dietary results in decreased expression of KLF5 mRNA] CTD PMID:17137605 NCBI chr15:82,472,081...82,487,267
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Myh4 myosin heavy chain 4 multiple interactions EXP udenafil inhibits the reaction [Cholesterol, Dietary results in increased expression of MYH4 mRNA] CTD PMID:17137605 NCBI chr10:51,923,149...51,946,297
Ensembl chr10:51,885,913...51,946,295 		JBrowse link
G Myl3 myosin light chain 3 multiple interactions EXP udenafil inhibits the reaction [Cholesterol, Dietary results in increased expression of MYL3 mRNA] CTD PMID:17137605 NCBI chr 8:119,617,077...119,623,215
Ensembl chr 8:110,738,661...110,744,816 		JBrowse link
G Ngf nerve growth factor decreases expression EXP udenafil results in decreased expression of NGF CTD PMID:21366883 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos1 nitric oxide synthase 1 increases expression EXP udenafil results in increased expression of NOS1 CTD PMID:21366883 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression EXP udenafil results in increased expression of NOS3 CTD PMID:21366883 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Oxa1l OXA1L, mitochondrial inner membrane protein multiple interactions EXP udenafil inhibits the reaction [Cholesterol, Dietary results in increased expression of OXA1L mRNA] CTD PMID:17137605 NCBI chr15:31,783,725...31,791,353
Ensembl chr15:27,813,625...27,821,319 		JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO udenafil results in decreased activity of PDE5A protein CTD PMID:17137605 NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Shh sonic hedgehog signaling molecule increases expression EXP udenafil results in increased expression of SHH CTD PMID:21366883 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP udenafil results in decreased expression of TGFB1 CTD PMID:21366883 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    chemical entity 19877
      atom 19877
        nonmetal atom 19800
          sulfur atom 17758
            sulfur molecular entity 17758
              organosulfur compound 17454
                sulfonamide 5310
                  udenafil 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    p-block element atom 19816
                      chalcogen 19569
                        oxygen atom 19541
                          oxygen molecular entity 19541
                            hydroxides 19350
                              oxoacid 18798
                                chalcogen oxoacid 13804
                                  sulfur oxoacid 13596
                                    sulfonic acid 11624
                                      sulfonic acid derivative 11624
                                        sulfonamide 5310
                                          udenafil 14
paths to the root