CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: omapatrilat
Accession: CHEBI:135660
browse the term
Synonyms: related_synonym: BMS-186716; Formula=C19H24N2O4S2; InChI=1S/C19H24N2O4S2/c22-17(15(26)11-12-5-2-1-3-6-12)20-13-9-10-27-16-8-4-7-14(19(24)25)21(16)18(13)23/h1-3,5-6,13-16,26H,4,7-11H2,(H,20,22)(H,24,25)/t13-,14-,15-,16-/m0/s1; InChIKey=LVRLSYPNFFBYCZ-VGWMRTNUSA-N; SMILES=C(O)(=O)[C@H]1N2[C@](CCC1)(SCC[C@@H](C2=O)NC([C@H](CC3=CC=CC=C3)S)=O)[H]
xref: CAS:167305-00-2; Drug_Central:1989
xref_mesh: MESH:C106266
G
Ace
angiotensin I converting enzyme
decreases activity
ISO
omapatrilat results in decreased activity of ACE protein
CTD
PMID:11762555
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
G
Mme
membrane metallo-endopeptidase
decreases activity
ISO
omapatrilat results in decreased activity of MME protein
CTD
PMID:18084312
NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
G
Mmel1
membrane metallo-endopeptidase-like 1
decreases activity
ISO
omapatrilat results in decreased activity of MMEL1 protein
CTD
PMID:18084312
NCBI chr 5:165,431,278...165,461,716
Ensembl chr 5:165,431,343...165,461,716
G
Nppa
natriuretic peptide A
increases expression
ISO
omapatrilat results in increased expression of NPPA protein
CTD
PMID:11762555
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all