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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ambroxol
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Accession:CHEBI:135590 term browser browse the term
Synonyms:related_synonym: Formula=C13H18Br2N2O;   InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2/t10-,11-;   InChIKey=JBDGDEWWOUBZPM-XYPYZODXSA-N;   SMILES=C(N[C@H]1CC[C@@H](CC1)O)C2=C(N)C(Br)=CC(=C2)Br;   ambroxils;   ambroxol HCl;   ambroxol hydrochloride;   lasolvan
 xref: CAS:18683-91-5;   Drug_Central:147
 xref_mesh: MESH:D000551


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ambroxol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of CCL2 mRNA] CTD PMID:21921364 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of COL1A1 mRNA] CTD PMID:21921364 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of COL3A1 mRNA] CTD PMID:21921364 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of MMP2 mRNA] CTD PMID:21921364 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Ambroxol inhibits the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:21921364 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions EXP Ambroxol inhibits the reaction [Paraquat results in decreased expression of SFTPA1 protein] CTD PMID:16824340 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of TGFB1 mRNA] CTD PMID:21921364 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of TIMP2 mRNA] CTD PMID:21921364 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of TNF mRNA] CTD PMID:21921364 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        NMR chemical shift reference compound 18065
          ammonia 17865
            organic amino compound 17865
              aromatic amine 15478
                ambroxol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            inorganic hydride 18156
                              pnictogen hydride 18146
                                nitrogen hydride 18059
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17865
                                        aromatic amine 15478
                                          ambroxol 9
paths to the root