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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bupranolol
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Accession:CHEBI:135123 term browser browse the term
Synonyms:related_synonym: Formula=C14H22ClNO2;   InChI=1S/C14H22ClNO2/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4/h5-7,11,16-17H,8-9H2,1-4H3;   InChIKey=HQIRNZOQPUAHHV-UHFFFAOYSA-N;   SMILES=O(CC(CNC(C)(C)C)O)C1=C(Cl)C=CC(=C1)C;   bupranol;   bupranolol HCl;   bupranolol hydrochloride
 xref: CAS:14556-46-8;   Drug_Central:433;   HMDB:HMDB0015697
 xref_mesh: MESH:D002046


show annotations for term's descendants           Sort by:
bupranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases activity 		ISO [Bupranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; Bupranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]
Bupranolol results in decreased activity of ADRB1 protein 		CTD PMID:2565296 PMID:12761341 PMID:15060759 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      group 20803
        polyatomic entity 20803
          molecule 20674
            organic molecule 20654
              organic cyclic compound 20404
                organic aromatic compound 20237
                  aromatic ether 16793
                    bupranolol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      p-block molecular entity 20781
                        carbon group molecular entity 20715
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  ether 17649
                                    aromatic ether 16793
                                      bupranolol 1
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