CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: cibenzoline
Accession: CHEBI:135083
browse the term
Synonyms: related_synonym: (RS)-Cibenzoline; Formula=C18H18N2; InChI=1S/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17/h1-10,16H,11-13H2,(H,19,20); InChIKey=IPOBOOXFSRWSHL-UHFFFAOYSA-N; SMILES=C1C(C1(C=2NCCN2)[H])(C3=CC=CC=C3)C4=CC=CC=C4; cibenzoline succinate; cifenline; cifenline succinate
xref: CAS:53267-01-9; Drug_Central:630
xref_mesh: MESH:C032151
G
Atf4
activating transcription factor 4
increases expression
ISO
cifenline results in increased expression of ATF4 protein
CTD
PMID:21292685
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
cifenline results in increased expression of DDIT3 protein
CTD
PMID:21292685
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
cifenline results in increased phosphorylation of EIF2A protein
CTD
PMID:21292685
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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Kcnh2
potassium voltage-gated channel subfamily H member 2
decreases activity
ISO
cifenline results in decreased activity of KCNH2 protein
CTD
PMID:24052561
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
G
Tnfsf10
TNF superfamily member 10
increases response to substance
ISO
cifenline results in increased susceptibility to TNFSF10 protein
CTD
PMID:21292685
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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