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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:perflubutane
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Accession:CHEBI:134964 term browser browse the term
Definition:A fluorocarbon that is butane in which all of the hydrogens have been replaced by fluorines. Microbubbles of preflubutane are used in the ultrasound contrast agent BR14.
Synonyms:exact_synonym: decafluorobutane
 related_synonym: Decafluoro-butane;   Formula=C4F10;   InChI=1S/C4F10/c5-1(6,3(9,10)11)2(7,8)4(12,13)14;   InChIKey=KAVGMUDTWQVPDF-UHFFFAOYSA-N;   SMILES=C(C(C(F)(F)F)(F)F)(C(F)(F)F)(F)F;   Sonazoid;   perflubutano;   perflubutanum;   perfluoro-n-butane;   perfluorobutane
 xref: CAS:355-25-9;   Drug_Central:3999;   KEGG:D05440
 xref_mesh: MESH:C108042
 xref: PMID:28000631;   Reaxys:1777513;   Wikipedia:Perfluorobutane



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot1 acyl-CoA thioesterase 1 increases expression EXP perfluorobutane results in increased expression of ACOT1 mRNA CTD PMID:19407336 NCBI chr 6:103,636,173...103,644,167 JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluorobutane results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797 JBrowse link
G Apoa2 apolipoprotein A2 affects expression ISO perfluorobutane affects the expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:83,644,460...83,646,358 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO perfluorobutane results in decreased expression of CCND1 mRNA CTD PMID:23567314 NCBI chr 1:209,518,288...209,527,986 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO perfluorobutane results in increased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:209,993,881...210,056,329 JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO perfluorobutane results in increased expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:120,491,354...120,500,833 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO perfluorobutane results in increased expression of CYP2B6 mRNA CTD PMID:23567314 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO perfluorobutane results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 NCBI chr 5:24,174,505...24,184,202 JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluorobutane results in increased expression of EHHADH mRNA CTD PMID:23567314 NCBI chr11:79,241,927...79,275,173 JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO perfluorobutane results in increased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:104,744,302...104,753,119 JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha affects expression ISO perfluorobutane affects the expression of HADHA mRNA CTD PMID:23567314 NCBI chr 6:26,187,969...26,227,605 JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 increases expression ISO perfluorobutane results in increased expression of MOGAT1 mRNA CTD PMID:23567314 NCBI chr 9:79,980,963...79,988,513 JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO perfluorobutane results in increased expression of NOS2 mRNA CTD PMID:23567314 NCBI chr10:64,313,335...64,349,221 JBrowse link
G Pank1 pantothenate kinase 1 increases expression ISO perfluorobutane results in increased expression of PANK1 mRNA CTD PMID:23567314 NCBI chr 1:241,737,371...241,808,126 JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluorobutane results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:34,558,327...34,568,329 JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluorobutane results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:106,202,634...106,258,748 JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO perfluorobutane results in increased expression of PPARD mRNA CTD PMID:23567314 NCBI chr20:6,300,527...6,365,707 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO perfluorobutane binds to PPARG protein CTD PMID:24998974 NCBI chr 4:150,095,743...150,221,104 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      molecular entity 19895
        main group molecular entity 19835
          gas molecular entity 18496
            perflubutane 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    main group molecular entity 19835
                      s-block molecular entity 19670
                        hydrogen molecular entity 19652
                          hydrides 19164
                            organic hydride 18711
                              organic fundamental parent 18711
                                hydrocarbon 18462
                                  halohydrocarbon 15878
                                    haloalkane 12915
                                      fluoroalkane 9234
                                        perflubutane 18
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