CHEBI ONTOLOGY - ANNOTATIONS |
|
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
|
Term: | primary allylic alcohol |
|
Accession: | CHEBI:134394
|
browse the term
|
Definition: | An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to two hydrogens. |
Synonyms: | related_synonym: | Formula=C3H3OR3; SMILES=C(C(=C(*)*)*)(O)([H])[H]; primary allylic alcohols |
|
|
|
G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression multiple interactions |
ISO |
[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of CEBPA mRNA [[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA] which results in decreased chemical synthesis of Cholesterol |
CTD |
PMID:23063590 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
|
|
G |
Dct |
dopachrome tautomerase |
decreases expression |
ISO |
artemisic acid results in decreased expression of DCT mRNA |
CTD |
PMID:23063590 |
|
NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions decreases expression |
ISO |
[[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA] which results in decreased chemical synthesis of Cholesterol; [artemisic acid results in decreased expression of HMGCR protein] which results in decreased chemical synthesis of Cholesterol [artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of HMGCR protein |
CTD |
PMID:23063590 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
|
G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
decreases expression |
ISO |
artemisic acid results in decreased expression of KIT mRNA |
CTD |
PMID:23063590 |
|
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
|
|
G |
Kitlg |
KIT ligand |
decreases expression |
ISO |
artemisic acid results in decreased expression of KITLG mRNA |
CTD |
PMID:23063590 |
|
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
|
|
G |
Mif |
macrophage migration inhibitory factor |
decreases expression |
ISO |
artemisic acid results in decreased expression of MIF mRNA |
CTD |
PMID:23063590 |
|
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
|
|
G |
Mitf |
melanocyte inducing transcription factor |
decreases expression |
ISO |
artemisic acid results in decreased expression of MITF mRNA |
CTD |
PMID:23063590 |
|
NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
|
|
G |
Tyr |
tyrosinase |
decreases expression |
ISO |
artemisic acid results in decreased expression of TYR mRNA |
CTD |
PMID:23063590 |
|
NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
|
|
G |
Tyrp1 |
tyrosinase-related protein 1 |
decreases expression |
ISO |
artemisic acid results in decreased expression of TYRP1 mRNA |
CTD |
PMID:23063590 |
|
NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
|
|
|
G |
Cdh1 |
cadherin 1 |
affects expression |
ISO |
4-oxoretinol affects the expression of CDH1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression |
ISO |
4-oxoretinol results in increased expression of COL1A1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
|
|
G |
Col4a2 |
collagen type IV alpha 2 chain |
increases expression |
ISO |
4-oxoretinol results in increased expression of COL4A2 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
|
|
G |
Crabp2 |
cellular retinoic acid binding protein 2 |
increases expression |
ISO |
4-oxoretinol results in increased expression of CRABP2 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
|
|
G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
affects chemical synthesis |
ISO |
CYP26A1 protein affects the chemical synthesis of 4-oxoretinol |
CTD |
PMID:10557354 |
|
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
|
|
G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
4-oxoretinol results in decreased expression of FAS mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
|
|
G |
Foxa1 |
forkhead box A1 |
increases expression |
ISO |
4-oxoretinol results in increased expression of FOXA1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
|
|
G |
Gata6 |
GATA binding protein 6 |
increases expression |
ISO |
4-oxoretinol results in increased expression of GATA6 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
|
|
G |
Itgam |
integrin subunit alpha M |
increases expression |
ISO |
4-oxoretinol results in increased expression of ITGAM protein |
CTD |
PMID:9581846 |
|
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
|
|
G |
Ivl |
involucrin |
increases expression |
ISO |
4-oxoretinol results in increased expression of IVL mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
|
|
G |
Krt18 |
keratin 18 |
increases expression |
ISO |
4-oxoretinol results in increased expression of KRT18 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
|
|
G |
Krt19 |
keratin 19 |
increases expression |
ISO |
4-oxoretinol results in increased expression of KRT19 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
|
|
G |
Krt7 |
keratin 7 |
increases expression |
ISO |
4-oxoretinol results in increased expression of KRT7 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
|
|
G |
Krt8 |
keratin 8 |
increases expression |
ISO |
4-oxoretinol results in increased expression of KRT8 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
|
|
G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
4-oxoretinol results in decreased expression of MCL1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
|
|
G |
Meis1 |
Meis homeobox 1 |
increases expression |
ISO |
4-oxoretinol results in increased expression of MEIS1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
|
|
G |
Meis2 |
Meis homeobox 2 |
increases expression |
ISO |
4-oxoretinol results in increased expression of MEIS2 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696
|
|
G |
Meox1 |
mesenchyme homeobox 1 |
increases expression |
ISO |
4-oxoretinol results in increased expression of MEOX1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
|
|
G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
increases expression |
ISO |
4-oxoretinol results in increased expression of MUC5AC mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
|
|
G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
increases expression |
ISO |
4-oxoretinol results in increased expression of OLR1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
|
|
G |
Rara |
retinoic acid receptor, alpha |
increases expression |
ISO |
4-oxoretinol results in increased expression of RARA mRNA |
CTD |
PMID:17034753 |
|
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
|
|
G |
Rarres1 |
retinoic acid receptor responder 1 |
increases expression |
ISO |
4-oxoretinol results in increased expression of RARRES1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
|
|
G |
Tgm2 |
transglutaminase 2 |
increases expression |
ISO |
4-oxoretinol results in increased expression of TGM2 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
|
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions decreases expression |
EXP |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA] Vitamin A results in decreased expression of ABCB1 mRNA; Vitamin A results in decreased expression of ABCB1A mRNA |
CTD |
PMID:15327746 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
|
|
G |
Ace2 |
angiotensin converting enzyme 2 |
increases expression |
ISO |
Vitamin A results in increased expression of ACE2 mRNA |
CTD |
PMID:32808185 |
|
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
|
|
G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of ACSS2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
Vitamin A inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] |
CTD |
PMID:16256175 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
|
|
G |
Actb |
actin, beta |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of ACTB mRNA |
CTD |
PMID:12163651 |
|
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
|
|
G |
Actg2 |
actin gamma 2, smooth muscle |
decreases expression multiple interactions |
EXP |
Vitamin A results in decreased expression of ACTG2 protein Vitamin A results in decreased expression of [Ethanol results in increased expression of ACTG2 protein] |
CTD |
PMID:16043492 |
|
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
|
|
G |
Afp |
alpha-fetoprotein |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of AFP mRNA |
CTD |
PMID:7519440 |
|
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions increases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased expression of AGER protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased expression of AGER protein]; [Vitamin A results in increased abundance of Reactive Oxygen Species] which results in increased expression of AGER protein; SB 203580 inhibits the reaction [Vitamin A results in increased expression of AGER protein] |
CTD |
PMID:18396385 PMID:21807062 PMID:22274401 |
|
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
|
|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA] |
CTD |
PMID:15728703 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
|
|
G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
decreases response to substance |
ISO |
AKR1B1 protein results in decreased susceptibility to Vitamin A; AKR1B1 protein results in decreased susceptibility to Vitamin A metabolite |
CTD |
PMID:19014918 |
|
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
|
|
G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
decreases response to substance |
ISO |
AKR1B10 protein results in decreased susceptibility to Vitamin A; AKR1B10 protein results in decreased susceptibility to Vitamin A metabolite |
CTD |
PMID:19014918 |
|
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:21807062 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
|
|
G |
Alb |
albumin |
affects binding |
ISO |
Vitamin A binds to ALB protein |
CTD |
PMID:17184834 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
|
|
G |
Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
decreases expression |
ISO |
Vitamin A results in decreased expression of ALDH1A2 mRNA |
CTD |
PMID:30944279 |
|
NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
|
|
G |
Aox1 |
aldehyde oxidase 1 |
multiple interactions |
ISO |
[Tetrachlorodibenzodioxin co-treated with Vitamin A] results in increased activity of AOX1 protein; [Tetrachlorodibenzodioxin co-treated with Vitamin A] results in increased expression of AOX1 mRNA; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AOX1 protein]; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AOX1 mRNA] |
CTD |
PMID:16292751 |
|
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
|
|
G |
Apod |
apolipoprotein D |
affects binding |
ISO |
Vitamin A binds to APOD protein |
CTD |
PMID:16461020 |
|
NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
|
|
G |
App |
amyloid beta precursor protein |
multiple interactions increases expression affects expression |
EXP |
Tretinoin inhibits the reaction [Vitamin A affects the expression of APP mRNA] Vitamin A results in increased expression of APP protein |
CTD |
PMID:16530976 PMID:22274401 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
|
|
G |
Ascl1 |
achaete-scute family bHLH transcription factor 1 |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of ASCL1 mRNA |
CTD |
PMID:12555267 |
|
NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
|
|
G |
Bace1 |
beta-secretase 1 |
multiple interactions affects expression |
EXP |
Tretinoin inhibits the reaction [Vitamin A affects the expression of BACE mRNA] |
CTD |
PMID:16530976 |
|
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
EXP |
Vitamin A results in increased expression of BAX protein |
CTD |
PMID:16216918 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
EXP |
Vitamin A results in decreased expression of BCL2 protein |
CTD |
PMID:16216918 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G |
Bmp4 |
bone morphogenetic protein 4 |
affects expression |
ISO |
Vitamin A affects the expression of BMP4 mRNA |
CTD |
PMID:16120438 |
|
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
|
|
G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Vitamin A results in increased expression of BTG2 mRNA |
CTD |
PMID:17234770 |
|
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
|
|
G |
Cab39 |
calcium binding protein 39 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of CAB39 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
|
|
G |
Casp3 |
caspase 3 |
multiple interactions decreases activity increases activity |
ISO |
alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein] Vitamin A results in decreased activity of CASP3 protein |
CTD |
PMID:16531423 PMID:17618090 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Cat |
catalase |
affects activity decreases activity increases expression multiple interactions decreases expression |
ISO EXP |
Vitamin A affects the activity of CAT protein Vitamin A results in decreased activity of CAT protein Vitamin A results in increased expression of CAT protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased expression of CAT protein]; [Vitamin A results in decreased activity of CAT protein] which results in increased abundance of Hydrogen Peroxide; Vitamin A results in increased expression of and results in increased activity of CAT protein Vitamin A deficiency results in decreased expression of CAT protein; Vitamin A results in decreased expression of CAT protein |
CTD |
PMID:8602878 PMID:16036340 PMID:17673185 PMID:17727954 PMID:18440196 PMID:18533141 PMID:19842843 PMID:22274401 More...
|
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases expression increases expression affects expression |
ISO EXP |
Vitamin A results in decreased expression of CCL2 protein Vitamin A results in increased expression of CCL2 mRNA Vitamin A affects the expression of CCL2 protein |
CTD |
PMID:16988133 PMID:25051504 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
|
|
G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Vitamin A results in decreased expression of CCND1 mRNA |
CTD |
PMID:17219422 PMID:17234770 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
|
|
G |
Ccnd2 |
cyclin D2 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of CCND2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
|
|
G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
Vitamin A results in increased expression of CD14 mRNA |
CTD |
PMID:17033190 |
|
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
|
|
G |
Cd44 |
CD44 molecule |
increases expression |
ISO |
Vitamin A results in increased expression of CD44 protein |
CTD |
PMID:16724877 |
|
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
|
|
G |
Cdh1 |
cadherin 1 |
affects expression |
ISO |
Vitamin A affects the expression of CDH1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression multiple interactions |
ISO |
Vitamin A results in increased expression of COL1A1 mRNA [Cryptoxanthins co-treated with Vitamin A] results in increased expression of COL1A1 mRNA |
CTD |
PMID:15962303 PMID:17034753 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
ISO |
[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA] |
CTD |
PMID:16397886 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G |
Col4a2 |
collagen type IV alpha 2 chain |
increases expression |
ISO |
Vitamin A results in increased expression of COL4A2 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
|
|
G |
Crabp2 |
cellular retinoic acid binding protein 2 |
multiple interactions increases expression |
ISO |
CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA] Vitamin A results in increased expression of CRABP2 mRNA |
CTD |
PMID:16793012 PMID:17034753 PMID:17234770 |
|
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
increases phosphorylation multiple interactions |
ISO EXP |
Vitamin A results in increased phosphorylation of CREB1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:16280361 PMID:16510265 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
|
|
G |
Ctnnb1 |
catenin beta 1 |
multiple interactions decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; MG 262 inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; Vitamin A results in increased ubiquitination of and results in increased degradation of CTNNB1 protein |
CTD |
PMID:17219422 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
|
|
G |
Cycs |
cytochrome c, somatic |
affects localization |
EXP |
Vitamin A affects the localization of CYCS protein |
CTD |
PMID:16202537 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Vitamin A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:15728703 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases oxidation decreases activity |
ISO |
CYP1B1 protein results in increased oxidation of Vitamin A Vitamin A results in decreased activity of CYP1B1 protein |
CTD |
PMID:15258110 PMID:33814510 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
|
|
G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions increases expression affects metabolic processing |
ISO EXP |
[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA Vitamin A results in increased expression of CYP26A1 mRNA [R 115866 co-treated with Vitamin A] results in increased expression of CYP26A1 mRNA CYP26A1 protein affects the metabolism of Vitamin A |
CTD |
PMID:10557354 PMID:16194896 PMID:17244623 PMID:17510468 PMID:22542753 PMID:30944279 More...
|
|
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
|
|
G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
[R 115866 co-treated with Vitamin A] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:17510468 |
|
NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
|
|
G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
EXP |
GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein]; Vitamin A affects the expression of and affects the activity of CYP2C11 protein |
CTD |
PMID:15963505 |
|
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
|
|
G |
Dcp2 |
decapping mRNA 2 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of DCP2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
|
|
G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] |
CTD |
PMID:16214399 |
|
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
|
|
G |
Dhh |
desert hedgehog signaling molecule |
multiple interactions |
EXP |
Vitamin A inhibits the reaction [Valproic Acid results in increased expression of DHH mRNA] |
CTD |
PMID:35594946 |
|
NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
|
|
G |
Dhrs3 |
dehydrogenase/reductase 3 |
decreases abundance |
ISO |
DHRS3 gene mutant form results in decreased abundance of Vitamin A |
CTD |
PMID:24005908 |
|
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
|
|
G |
Dhrs9 |
dehydrogenase/reductase 9 |
increases metabolic processing |
ISO |
DHRS9 protein results in increased metabolism of Vitamin A |
CTD |
PMID:11304534 |
|
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
|
|
G |
Drd2 |
dopamine receptor D2 |
decreases expression |
EXP |
Vitamin A results in decreased expression of DRD2 protein |
CTD |
PMID:22274401 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
|
|
G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of EEF1A1 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
|
|
G |
Egfr |
epidermal growth factor receptor |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of EGFR mRNA |
CTD |
PMID:7519440 |
|
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
|
|
G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of EIF4A2 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
|
|
G |
Epo |
erythropoietin |
increases expression multiple interactions |
ISO EXP |
Vitamin A results in increased expression of EPO protein Vitamin A inhibits the reaction [Hydrogen Peroxide results in decreased expression of EPO protein] |
CTD |
PMID:9927288 PMID:16960172 |
|
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
|
|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Vitamin A inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] |
CTD |
PMID:19340624 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
|
|
G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
Vitamin A results in decreased expression of FAS mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
|
|
G |
Fn1 |
fibronectin 1 |
decreases secretion |
ISO |
Vitamin A results in decreased secretion of FN1 protein |
CTD |
PMID:17225872 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
|
|
G |
Fnta |
farnesyltransferase, CAAX box, subunit alpha |
multiple interactions |
EXP |
[Vitamin A co-treated with perillyl alcohol] results in decreased expression of FNTA protein |
CTD |
PMID:15959631 |
|
NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
|
|
G |
Fntb |
farnesyltransferase, CAAX box, subunit beta |
multiple interactions increases expression |
EXP |
[perillyl alcohol co-treated with Vitamin A] results in decreased expression of FNTB mRNA Vitamin A results in increased expression of FNTB mRNA; Vitamin A results in increased expression of FNTB protein |
CTD |
PMID:15959631 |
|
NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
|
|
G |
Foxa1 |
forkhead box A1 |
increases expression |
ISO |
Vitamin A results in increased expression of FOXA1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
|
|
G |
Foxa2 |
forkhead box A2 |
multiple interactions |
EXP |
Vitamin A inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein] |
CTD |
PMID:16863852 |
|
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
|
|
G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions decreases expression |
EXP |
Iron deficiency promotes the reaction [Vitamin A deficiency results in decreased expression of FTH1 protein] Vitamin A deficiency results in decreased expression of FTH1 mRNA; Vitamin A deficiency results in decreased expression of FTH1 protein |
CTD |
PMID:22154532 |
|
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
|
|
G |
Gabrb3 |
gamma-aminobutyric acid type A receptor subunit beta 3 |
increases expression |
ISO |
Vitamin A results in increased expression of GABRB3 mRNA |
CTD |
PMID:17225872 |
|
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
|
|
G |
Gata6 |
GATA binding protein 6 |
increases expression |
ISO |
Vitamin A results in increased expression of GATA6 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
|
|
G |
Gcg |
glucagon |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of GCG mRNA |
CTD |
PMID:17244017 |
|
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
|
|
G |
Gh1 |
growth hormone 1 |
multiple interactions |
EXP |
GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein] |
CTD |
PMID:15963505 |
|
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
|
|
G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions increases expression |
EXP |
Vitamin A inhibits the reaction [nitrofen results in increased expression of GJA1 mRNA] Vitamin A results in increased expression of GJA1 mRNA |
CTD |
PMID:12031251 PMID:16292552 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
|
|
G |
Gnai1 |
G protein subunit alpha i1 |
increases expression |
EXP |
Vitamin A results in increased expression of GNAI1 protein |
CTD |
PMID:16757122 |
|
NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
|
|
G |
Gnai2 |
G protein subunit alpha i2 |
increases expression |
EXP |
Vitamin A results in increased expression of GNAI2 protein |
CTD |
PMID:16757122 |
|
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
increases activity multiple interactions |
EXP |
Vitamin A results in increased activity of GPT protein gadolinium chloride inhibits the reaction [Vitamin A results in increased activity of GPT protein] |
CTD |
PMID:8627517 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
[Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein |
CTD |
PMID:17179735 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Grhl3 |
grainyhead-like transcription factor 3 |
increases response to substance |
ISO |
GRHL3 gene mutant form results in increased susceptibility to Vitamin A |
CTD |
PMID:6635991 |
|
NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
Vitamin A inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
|
|
G |
H3f4 |
H3.4 histone, cluster member |
multiple interactions increases acetylation |
ISO |
Vitamin A affects the reaction [H3F4 protein modified form binds to PCK1 promoter] Vitamin A results in increased acetylation of H3F4 protein |
CTD |
PMID:16317119 |
|
NCBI chr10:43,740,702...43,741,262
|
|
G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
ISO |
Vitamin A results in increased expression of HBEGF mRNA |
CTD |
PMID:19648781 |
|
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
|
|
G |
Hoxa1 |
homeobox A1 |
multiple interactions increases expression |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased expression of HOXA1]; 3,4-methylenedioxy-beta-nitrostyrene inhibits the reaction [Vitamin A results in increased expression of HOXA1]; 4-nonylphenol inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; BAY 11-7085 inhibits the reaction [Vitamin A results in increased expression of HOXA1]; bisphenol A inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Camptothecin inhibits the reaction [Vitamin A results in increased expression of HOXA1]; citral inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; di-n-pentyl phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Dibutyl Phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Diethylstilbestrol inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; Genistein inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA]; nitrofen inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] Vitamin A results in increased expression of HOXA1; Vitamin A results in increased expression of HOXA1 mRNA |
CTD |
PMID:23696197 PMID:26820057 |
|
NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
|
|
G |
Hoxa3 |
homeobox A3 |
affects expression |
ISO |
Vitamin A affects the expression of HOXA3 mRNA |
CTD |
PMID:10992263 |
|
NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218
|
|
G |
Ifng |
interferon gamma |
decreases expression affects expression |
ISO EXP |
Vitamin A results in decreased expression of IFNG protein Vitamin A affects the expression of IFNG protein |
CTD |
PMID:14624943 PMID:17289162 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Il1b |
interleukin 1 beta |
increases expression |
EXP |
Vitamin A results in increased expression of IL1B protein |
CTD |
PMID:25051504 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il2 |
interleukin 2 |
increases expression |
ISO |
Vitamin A results in increased expression of IL2 mRNA |
CTD |
PMID:15506942 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
|
|
G |
Il4 |
interleukin 4 |
decreases expression |
ISO |
Vitamin A results in decreased expression of IL4 protein |
CTD |
PMID:14624943 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Inhba |
inhibin subunit beta A |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in decreased expression of SHH mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of GCG mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of INS1 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of INS2 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PDX1 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PPY mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of PTF1A mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA; [Vitamin A co-treated with INHBA protein] results in increased expression of SST mRNA |
CTD |
PMID:17244017 |
|
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
|
|
G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of INS1 mRNA |
CTD |
PMID:17244017 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
|
G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of INS2 mRNA |
CTD |
PMID:17244017 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
|
|
G |
Ireb2 |
iron responsive element binding protein 2 |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of IREB2 mRNA |
CTD |
PMID:22154532 |
|
NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
|
|
G |
Itga3 |
integrin subunit alpha 3 |
increases expression |
ISO |
Vitamin A results in increased expression of ITGA3 protein |
CTD |
PMID:17241391 |
|
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
|
|
G |
Itgb1 |
integrin subunit beta 1 |
affects localization increases expression |
ISO |
Vitamin A affects the localization of ITGB1 protein Vitamin A results in increased expression of ITGB1 protein |
CTD |
PMID:17241391 |
|
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
|
|
G |
Ivl |
involucrin |
increases expression |
ISO |
Vitamin A results in increased expression of IVL mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
|
|
G |
Jak2 |
Janus kinase 2 |
affects localization |
EXP |
Vitamin A affects the localization of JAK2 protein |
CTD |
PMID:15963505 |
|
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
|
|
G |
Krt18 |
keratin 18 |
increases expression |
ISO |
Vitamin A results in increased expression of KRT18 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
|
|
G |
Krt19 |
keratin 19 |
increases expression decreases expression |
ISO EXP |
Vitamin A results in increased expression of KRT19 mRNA Vitamin A deficiency results in decreased expression of KRT19 mRNA |
CTD |
PMID:12163651 PMID:17034753 |
|
NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
|
|
G |
Krt7 |
keratin 7 |
increases expression |
ISO |
Vitamin A results in increased expression of KRT7 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
|
|
G |
Krt8 |
keratin 8 |
increases expression |
ISO |
Vitamin A results in increased expression of KRT8 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
|
|
G |
Lep |
leptin |
multiple interactions |
EXP |
LEP gene mutant form promotes the reaction [Vitamin A results in increased expression of UCP1 mRNA] |
CTD |
PMID:16493122 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
|
|
G |
Lrat |
lecithin retinol acyltransferase |
multiple interactions decreases expression affects expression increases expression |
ISO EXP |
[STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin A Vitamin A results in decreased expression of LRAT mRNA Vitamin A affects the expression of LRAT mRNA Vitamin A results in increased expression of LRAT mRNA [Vitamin A co-treated with Tetrachlorodibenzodioxin] results in increased expression of LRAT mRNA; Tetrachlorodibenzodioxin inhibits the reaction [Vitamin A results in increased expression of LRAT mRNA] |
CTD |
PMID:12576510 PMID:16292751 PMID:18316031 PMID:30944279 |
|
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
|
|
G |
Lrp2 |
LDL receptor related protein 2 |
multiple interactions |
ISO |
LRP2 protein results in increased uptake of and affects the abundance of Vitamin A |
CTD |
PMID:16251603 |
|
NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
|
|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions increases phosphorylation |
EXP |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] |
CTD |
PMID:16510265 |
|
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions increases phosphorylation |
EXP |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] |
CTD |
PMID:16510265 |
|
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK1 protein]; Vitamin A results in decreased phosphorylation of and results in decreased activity of MAPK1 protein |
CTD |
PMID:16043492 PMID:16510265 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Vitamin A results in increased phosphorylation of MAPK3 protein]; Vitamin A results in decreased phosphorylation of and results in decreased activity of MAPK3 protein |
CTD |
PMID:16043492 PMID:16510265 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mbl2 |
mannose binding lectin 2 |
multiple interactions |
ISO |
MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] |
CTD |
PMID:16960176 |
|
NCBI chr 1:228,016,439...228,024,736
|
|
G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
affects expression |
ISO |
Vitamin A affects the expression of MCL1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
|
|
G |
Meis1 |
Meis homeobox 1 |
increases expression multiple interactions |
ISO |
Vitamin A results in increased expression of MEIS1 mRNA [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA] |
CTD |
PMID:16397886 PMID:17034753 |
|
NCBI chr14:93,155,426...93,294,373
Ensembl chr14:93,155,419...93,294,265
|
|
G |
Meis2 |
Meis homeobox 2 |
increases expression multiple interactions |
ISO |
Vitamin A results in increased expression of MEIS2 mRNA [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA] |
CTD |
PMID:16397886 PMID:17034753 |
|
NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696
|
|
G |
Meox1 |
mesenchyme homeobox 1 |
increases expression |
ISO |
Vitamin A results in increased expression of MEOX1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
|
|
G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of COX3 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
|
|
G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
increases expression |
ISO |
Vitamin A results in increased expression of MUC5AC mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
Vitamin A results in decreased expression of MYC mRNA |
CTD |
PMID:17219422 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
|
|
G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions |
ISO |
Vitamin A affects the reaction [NCOA1 protein binds to PCK1 promoter] |
CTD |
PMID:16317119 |
|
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
|
|
G |
Neurog3 |
neurogenin 3 |
decreases expression |
ISO |
Vitamin A results in decreased expression of NEUROG3 mRNA |
CTD |
PMID:30944279 |
|
NCBI chr20:30,079,780...30,081,262
Ensembl chr20:30,079,780...30,081,262
|
|
G |
Nkx2-1 |
NK2 homeobox 1 |
multiple interactions |
ISO EXP |
Vitamin A inhibits the reaction [nitrofen results in decreased expression of NKX2-1 mRNA] Vitamin A inhibits the reaction [nitrofen results in decreased expression of NKX2-1 protein] |
CTD |
PMID:16490937 PMID:16863852 |
|
NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791
|
|
G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of NOS2 |
CTD |
PMID:16036340 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
|
|
G |
Nos3 |
nitric oxide synthase 3 |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of NOS3 |
CTD |
PMID:16036340 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
|
|
G |
Npy1r |
neuropeptide Y receptor Y1 |
increases response to substance |
ISO |
NPY1R protein results in increased susceptibility to Vitamin A |
CTD |
PMID:17400914 |
|
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
|
|
G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
NR1I3 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased abundance of Vitamin A] |
CTD |
PMID:31449830 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
|
|
G |
Nrgn |
neurogranin |
affects expression |
EXP |
Vitamin A affects the expression of NRGN mRNA |
CTD |
PMID:14529804 |
|
NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516
|
|
G |
Odc1 |
ornithine decarboxylase 1 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of ODC1 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
|
|
G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
increases expression |
ISO |
Vitamin A results in increased expression of OLR1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
|
|
G |
Oprm1 |
opioid receptor, mu 1 |
affects expression |
EXP |
Vitamin A affects the expression of OPRM1 mRNA; Vitamin A affects the expression of OPRM1 protein |
CTD |
PMID:17289162 |
|
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
|
|
G |
Pax3 |
paired box 3 |
multiple interactions |
EXP |
Vitamin A inhibits the reaction [nitrofen results in decreased expression of PAX3 mRNA] |
CTD |
PMID:16481245 |
|
NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
|
|
G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
affects expression multiple interactions |
ISO |
Vitamin A affects the expression of PCK1 mRNA [Tretinoin co-treated with Alitretinoin] affects the reaction [Vitamin A affects the expression of PCK1 mRNA]; Vitamin A affects the reaction [H3F4 protein modified form binds to PCK1 promoter]; Vitamin A affects the reaction [NCOA1 protein binds to PCK1 promoter]; Vitamin A affects the reaction [PPARA protein binds to PCK1 promoter]; Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter] |
CTD |
PMID:16317119 PMID:16713227 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
|
|
G |
Pdx1 |
pancreatic and duodenal homeobox 1 |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of PDX1 mRNA |
CTD |
PMID:17244017 |
|
NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
|
|
G |
Pomc |
proopiomelanocortin |
increases expression |
EXP |
Vitamin A results in increased expression of POMC protein |
CTD |
PMID:17373634 |
|
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
Vitamin A affects the reaction [PPARA protein binds to PCK1 promoter] |
CTD |
PMID:16713227 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
EXP |
Vitamin A inhibits the reaction [Safflower Oil results in increased expression of PPARG mRNA] Vitamin A results in increased expression of PPARG mRNA |
CTD |
PMID:15203375 PMID:16180333 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
|
|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter] |
CTD |
PMID:16317119 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
|
|
G |
Ppy |
pancreatic polypeptide |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of PPY mRNA |
CTD |
PMID:17244017 |
|
NCBI chr10:87,054,747...87,056,044
Ensembl chr10:87,054,756...87,055,455
|
|
G |
Prm1 |
protamine 1 |
decreases expression |
ISO |
Vitamin A results in decreased expression of PRM1 mRNA |
CTD |
PMID:30944279 |
|
NCBI chr10:4,871,817...4,872,312
|
|
G |
Ptf1a |
pancreas associated transcription factor 1a |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of PTF1A mRNA |
CTD |
PMID:17244017 |
|
NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135
|
|
G |
Ptgds |
prostaglandin D2 synthase |
affects binding |
ISO |
Vitamin A binds to PTGDS protein |
CTD |
PMID:16461020 |
|
NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of PTGS2 |
CTD |
PMID:16036340 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
|
|
G |
Ptpn6 |
protein tyrosine phosphatase, non-receptor type 6 |
multiple interactions |
EXP |
Vitamin A affects the localization of and affects the phosphorylation of PTPN6 protein |
CTD |
PMID:15963505 |
|
NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
|
|
G |
Rara |
retinoic acid receptor, alpha |
multiple interactions increases expression |
ISO EXP |
[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA [Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RARA protein; [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter] Vitamin A results in increased expression of RARA mRNA Vitamin A deficiency results in increased expression of RARA mRNA [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA; [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA] |
CTD |
PMID:7519440 PMID:16397886 PMID:17034753 PMID:17225872 PMID:17244623 PMID:30944279 PMID:32526256 More...
|
|
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
|
|
G |
Rarb |
retinoic acid receptor, beta |
decreases expression affects expression multiple interactions increases expression |
ISO EXP |
Vitamin A results in decreased expression of RARB mRNA Vitamin A affects the expression of RARB mRNA Vitamin A deficiency results in decreased expression of RARB mRNA [R 115866 co-treated with Vitamin A] results in increased expression of RARB mRNA; Tretinoin inhibits the reaction [Vitamin A affects the expression of RARB mRNA]; Vitamin A inhibits the reaction [Safflower Oil results in decreased expression of RARB mRNA] Vitamin A results in increased expression of RARB mRNA |
CTD |
PMID:7519440 PMID:14529804 PMID:15203375 PMID:15754000 PMID:16530976 PMID:17034753 PMID:17510468 PMID:30944279 More...
|
|
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
|
|
G |
Rarg |
retinoic acid receptor, gamma |
multiple interactions |
ISO |
RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA] |
CTD |
PMID:16397886 |
|
NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
|
|
G |
Rarres1 |
retinoic acid receptor responder 1 |
increases expression |
ISO |
Vitamin A results in increased expression of RARRES1 mRNA |
CTD |
PMID:17034753 |
|
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
|
|
G |
Rbp1 |
retinol binding protein 1 |
increases uptake increases abundance multiple interactions affects expression increases expression |
ISO EXP |
RBP1 protein results in increased uptake of Vitamin A RBP1 gene mutant form results in increased abundance of Vitamin A [RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNA Vitamin A affects the expression of RBP1 mRNA Vitamin A results in increased expression of RBP1 mRNA |
CTD |
PMID:12576510 PMID:16150442 PMID:16793012 PMID:21670153 |
|
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
|
|
G |
Rbp2 |
retinol binding protein 2 |
multiple interactions |
ISO |
[RBP1 gene mutant form results in increased abundance of Vitamin A] which results in increased expression of RBP2 mRNA |
CTD |
PMID:21670153 |
|
NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473
|
|
G |
Rbp4 |
retinol binding protein 4 |
affects binding multiple interactions increases secretion decreases secretion |
ISO |
Vitamin A binds to RBP4 protein Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]; Vitamin A results in decreased expression of and results in decreased secretion of RBP4 protein Vitamin A results in increased secretion of RBP4 protein Vitamin A deficiency results in decreased secretion of RBP4 protein |
CTD |
PMID:16461020 PMID:16762690 PMID:18316031 PMID:21591606 PMID:22001960 PMID:22542753 More...
|
|
NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
|
|
G |
Rdh10 |
retinol dehydrogenase 10 |
increases oxidation |
ISO |
RDH10 protein results in increased oxidation of Vitamin A |
CTD |
PMID:17473173 |
|
NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572
|
|
G |
Rdh11 |
retinol dehydrogenase 11 |
increases oxidation |
ISO |
RDH11 protein results in increased oxidation of Vitamin A |
CTD |
PMID:16968212 |
|
NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252
|
|
G |
Rdh12 |
retinol dehydrogenase 12 |
increases chemical synthesis |
ISO |
RDH12 protein results in increased chemical synthesis of Vitamin A |
CTD |
PMID:16269441 |
|
NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388
|
|
G |
Rdh5 |
retinol dehydrogenase 5 |
increases oxidation |
ISO |
RDH5 protein results in increased oxidation of Vitamin A |
CTD |
PMID:16968212 |
|
NCBI chr 7:1,341,172...1,346,863
Ensembl chr 7:1,340,934...1,351,558
|
|
G |
Ret |
ret proto-oncogene |
multiple interactions |
EXP |
[Valproic Acid co-treated with Vitamin A deficiency] affects the expression of RET protein; [Valproic Acid co-treated with Vitamin A deficiency] affects the reaction [RARA protein binds to RET promoter] |
CTD |
PMID:32526256 |
|
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
|
|
G |
Retn |
resistin |
decreases expression |
ISO |
Vitamin A results in decreased expression of RETN mRNA |
CTD |
PMID:15047602 |
|
NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
|
|
G |
Rhoa |
ras homolog family member A |
multiple interactions increases expression |
EXP |
[perillyl alcohol co-treated with Vitamin A] results in increased expression of RHOA mRNA Vitamin A results in increased expression of RHOA mRNA |
CTD |
PMID:15959631 |
|
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
|
|
G |
Rhob |
ras homolog family member B |
multiple interactions increases expression |
EXP |
[perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB mRNA; [perillyl alcohol co-treated with Vitamin A] affects the expression of RHOB protein Vitamin A results in increased expression of RHOB mRNA; Vitamin A results in increased expression of RHOB protein |
CTD |
PMID:15959631 |
|
NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
|
|
G |
Rora |
RAR-related orphan receptor A |
multiple interactions |
EXP |
Vitamin A deficiency promotes the reaction [Valproic Acid results in decreased expression of RORA protein] |
CTD |
PMID:33991534 |
|
NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
|
|
G |
Rpe65 |
retinoid isomerohydrolase RPE65 |
increases chemical synthesis increases metabolic processing |
ISO |
RPE65 protein results in increased chemical synthesis of Vitamin A RPE65 protein results in increased metabolism of Vitamin A |
CTD |
PMID:16150724 PMID:16828753 |
|
NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
|
|
G |
Runx2 |
RUNX family transcription factor 2 |
multiple interactions |
ISO |
[Cryptoxanthins co-treated with Vitamin A] results in increased expression of RUNX2 mRNA |
CTD |
PMID:15962303 |
|
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
|
|
G |
Rxra |
retinoid X receptor alpha |
multiple interactions increases expression |
ISO EXP |
[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA Vitamin A results in increased expression of RXRA mRNA Vitamin A results in increased expression of RXRA protein |
CTD |
PMID:16180333 PMID:17219422 PMID:17244623 |
|
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
|
|
G |
Rxrb |
retinoid X receptor beta |
affects expression |
EXP |
Vitamin A affects the expression of RXRB mRNA |
CTD |
PMID:14529804 |
|
NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
|
|
G |
Rxrg |
retinoid X receptor gamma |
affects expression decreases expression increases expression |
EXP ISO |
Vitamin A affects the expression of RXRG mRNA Vitamin A results in decreased expression of RXRG mRNA Vitamin A results in increased expression of RXRG protein |
CTD |
PMID:14529804 PMID:17219422 PMID:30944279 |
|
NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
|
|
G |
Sdr16c5 |
short chain dehydrogenase/reductase family 16C, member 5 |
increases oxidation increases metabolic processing |
ISO |
SDR16C5 protein results in increased oxidation of Vitamin A SDR16C5 protein results in increased metabolism of Vitamin A |
CTD |
PMID:18926804 PMID:27793605 |
|
NCBI chr 5:17,018,813...17,043,974
Ensembl chr 5:17,018,813...17,040,970
|
|
G |
Sftpb |
surfactant protein B |
multiple interactions |
EXP ISO |
Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPB mRNA]; Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPB protein] |
CTD |
PMID:11588001 PMID:16490937 PMID:16863852 |
|
NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
|
|
G |
Sftpc |
surfactant protein C |
multiple interactions decreases expression |
EXP |
Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPC mRNA] Vitamin A results in decreased expression of SFTPC protein |
CTD |
PMID:11588001 |
|
NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
|
|
G |
Shh |
sonic hedgehog signaling molecule |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in decreased expression of SHH mRNA |
CTD |
PMID:17244017 |
|
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
|
|
G |
Slc1a2 |
solute carrier family 1 member 2 |
multiple interactions increases expression |
ISO |
Vitamin A promotes the reaction [Corticosterone results in increased expression of SLC1A2 protein] Vitamin A results in increased expression of SLC1A2 protein |
CTD |
PMID:17138558 |
|
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
|
|
G |
Slc30a1 |
solute carrier family 30 member 1 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of SLC30A1 protein |
CTD |
PMID:12421840 |
|
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
|
|
G |
Slc30a2 |
solute carrier family 30 member 2 |
multiple interactions |
EXP |
[Zinc deficiency co-treated with Vitamin A deficiency] results in increased expression of SLC30A2 mRNA |
CTD |
PMID:12421840 |
|
NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956
|
|
G |
Slc30a4 |
solute carrier family 30 member 4 |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of SLC30A4 mRNA; Vitamin A deficiency results in increased expression of SLC30A4 protein |
CTD |
PMID:12421840 |
|
NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306
|
|
G |
Snca |
synuclein alpha |
increases expression |
EXP |
Vitamin A results in increased expression of SNCA protein |
CTD |
PMID:22274401 |
|
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
|
|
G |
Sncb |
synuclein, beta |
decreases expression |
EXP |
Vitamin A results in decreased expression of SNCB protein |
CTD |
PMID:22274401 |
|
NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
|
|
G |
Sod1 |
superoxide dismutase 1 |
increases activity |
EXP |
Vitamin A results in increased activity of SOD1 protein |
CTD |
PMID:22274401 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
|
|
G |
Sod2 |
superoxide dismutase 2 |
increases activity |
EXP |
Vitamin A results in increased activity of SOD2 protein |
CTD |
PMID:22274401 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
|
|
G |
Sox17 |
SRY-box transcription factor 17 |
multiple interactions |
ISO |
[Vitamin A co-treated with INHBA protein] results in increased expression of SOX17 mRNA |
CTD |
PMID:17244017 |
|
NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
|
|
G |
Sox9 |
SRY-box transcription factor 9 |
multiple interactions |
ISO |
[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA; RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA] |
CTD |
PMID:16397886 |
|
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
|
|
G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions increases phosphorylation |
EXP |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein]; Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] |
CTD |
PMID:16510265 |
|
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
|
|
G |
Sst |
somatostatin |
multiple interactions affects expression |
ISO EXP |
[Vitamin A co-treated with INHBA protein] results in increased expression of SST mRNA Vitamin A affects the expression of SST protein |
CTD |
PMID:16757122 PMID:17244017 |
|
NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
affects expression |
EXP |
Vitamin A affects the expression of STAT3 protein |
CTD |
PMID:15963505 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
|
|
G |
Stat5a |
signal transducer and activator of transcription 5A |
multiple interactions |
EXP |
Vitamin A affects the phosphorylation of and affects the localization of STAT5A protein |
CTD |
PMID:15963505 |
|
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
|
|
G |
Stra6 |
signaling receptor and transporter of retinol STRA6 |
multiple interactions increases transport |
ISO |
[STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin A STRA6 protein results in increased transport of Vitamin A |
CTD |
PMID:18316031 |
|
NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860
|
|
G |
Stra8 |
stimulated by retinoic acid 8 |
increases expression |
ISO |
Vitamin A results in increased expression of STRA8 mRNA |
CTD |
PMID:16461896 |
|
NCBI chr 4:63,601,443...63,624,777
Ensembl chr 4:63,601,604...63,624,771
|
|
G |
Sycp3 |
synaptonemal complex protein 3 |
decreases expression |
ISO |
Vitamin A results in decreased expression of SYCP3 mRNA |
CTD |
PMID:30944279 |
|
NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511
|
|
G |
Tfrc |
transferrin receptor |
decreases expression increases expression |
ISO EXP |
Vitamin A results in decreased expression of TFRC protein Vitamin A deficiency results in increased expression of TFRC mRNA; Vitamin A deficiency results in increased expression of TFRC protein |
CTD |
PMID:16960172 PMID:22154532 |
|
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
|
|
G |
Tgfa |
transforming growth factor alpha |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of TGFA mRNA |
CTD |
PMID:7519440 |
|
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
|
|
G |
Tgfb3 |
transforming growth factor, beta 3 |
increases expression |
ISO |
Vitamin A results in increased expression of TGFB3 mRNA |
CTD |
PMID:17225872 |
|
NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
|
|
G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
decreases expression |
ISO |
Vitamin A results in decreased expression of TGFBR1 mRNA |
CTD |
PMID:17225872 |
|
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
|
|
G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
increases expression |
ISO |
Vitamin A results in increased expression of TGFBR2 mRNA |
CTD |
PMID:17225872 |
|
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
|
|
G |
Tgm2 |
transglutaminase 2 |
increases expression affects expression |
ISO EXP |
Vitamin A results in increased expression of TGM2 mRNA Vitamin A affects the expression of TGM2 mRNA |
CTD |
PMID:14529804 PMID:17034753 |
|
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
|
|
G |
Tlr2 |
toll-like receptor 2 |
increases expression |
ISO |
Vitamin A results in increased expression of TLR2 mRNA |
CTD |
PMID:17033190 |
|
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
|
|
G |
Tlr4 |
toll-like receptor 4 |
increases expression |
ISO |
Vitamin A results in increased expression of TLR4 mRNA |
CTD |
PMID:17033190 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
|
|
G |
Tmem245 |
transmembrane protein 245 |
decreases expression |
EXP |
Vitamin A deficiency results in decreased expression of TMEM245 mRNA |
CTD |
PMID:12163651 |
|
NCBI chr 5:71,570,952...71,647,915
Ensembl chr 5:71,514,858...71,647,763
|
|
G |
Tnf |
tumor necrosis factor |
affects secretion increases expression |
EXP |
Vitamin A affects the secretion of TNF protein Vitamin A results in increased expression of TNF mRNA; Vitamin A results in increased expression of TNF protein |
CTD |
PMID:15135310 PMID:17289162 PMID:22274401 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Tob1 |
transducer of ErbB-2.1 |
multiple interactions increases expression |
ISO |
CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA] |
CTD |
PMID:17234770 |
|
NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
|
|
G |
Tpi1 |
triosephosphate isomerase 1 |
increases expression |
EXP |
Vitamin A results in increased expression of TPI1 mRNA alternative form |
CTD |
PMID:8793052 |
|
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
|
|
G |
Ttr |
transthyretin |
multiple interactions |
ISO |
Fenretinide analog inhibits the reaction [Vitamin A promotes the reaction [RBP4 protein binds to TTR protein]]; Vitamin A promotes the reaction [RBP4 protein binds to TTR protein] |
CTD |
PMID:21591606 |
|
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
|
|
G |
Ubc |
ubiquitin C |
increases expression |
EXP |
Vitamin A deficiency results in increased expression of UBC mRNA |
CTD |
PMID:12163651 |
|
NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
|
|
G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
multiple interactions |
EXP |
[Valproic Acid co-treated with Vitamin A deficiency] affects the expression of UCHL1 protein |
CTD |
PMID:32526256 |
|
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
|
|
G |
Ucp1 |
uncoupling protein 1 |
multiple interactions |
EXP |
LEP gene mutant form promotes the reaction [Vitamin A results in increased expression of UCP1 mRNA] |
CTD |
PMID:16493122 |
|
NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
|
|
G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
multiple interactions |
EXP |
Vitamin A inhibits the reaction [Triiodothyronine results in decreased expression of UGT1A1 mRNA] |
CTD |
PMID:11299074 |
|
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
|
|
G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
multiple interactions decreases expression |
EXP |
Vitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA] Vitamin A deficiency results in decreased expression of UGT1A6 mRNA |
CTD |
PMID:11299074 PMID:12163651 |
|
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
|
|
|
G |
Cat |
catalase |
increases activity |
EXP |
retinol palmitate results in increased activity of CAT protein |
CTD |
PMID:20679000 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
EXP |
retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein] |
CTD |
PMID:17164434 |
|
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
|
|
G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] |
CTD |
PMID:17377406 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
ISO |
retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1RN protein] |
CTD |
PMID:17377406 |
|
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
|
|
G |
Lipe |
lipase E, hormone sensitive type |
increases hydrolysis multiple interactions |
ISO |
LIPE protein results in increased hydrolysis of retinol palmitate PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate] |
CTD |
PMID:16741517 |
|
NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
EXP |
retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein]; retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein] retinol palmitate results in increased expression of MMP9 mRNA |
CTD |
PMID:17164434 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
|
|
G |
Plin3 |
perilipin 3 |
multiple interactions |
ISO |
PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]; PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] |
CTD |
PMID:16741517 |
|
NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
|
|
G |
Pnpla4 |
patatin like phospholipase domain containing 4 |
increases hydrolysis multiple interactions |
ISO |
PNPLA4 protein results in increased hydrolysis of retinol palmitate PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] |
CTD |
PMID:16741517 |
|
NCBI chr X:42,313,554...42,318,451
Ensembl chr X:42,305,373...42,318,552
|
|
G |
Rara |
retinoic acid receptor, alpha |
multiple interactions |
EXP |
retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein] |
CTD |
PMID:17164434 |
|
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
|
|
G |
Scarb1 |
scavenger receptor class B, member 1 |
increases expression |
EXP |
retinol palmitate results in increased expression of SCARB1 mRNA |
CTD |
PMID:17299104 |
|
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
|
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
allyl alcohol results in increased expression of ABCC1 mRNA; allyl alcohol results in increased expression of ABCC1 protein |
CTD |
PMID:19371622 |
|
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases expression |
ISO |
allyl alcohol results in increased expression of ABCC2 protein |
CTD |
PMID:19371622 |
|
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
|
|
G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
allyl alcohol results in increased expression of ABCC3 mRNA |
CTD |
PMID:19371622 |
|
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
|
|
G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases expression |
ISO |
allyl alcohol results in increased expression of ABCC4 mRNA; allyl alcohol results in increased expression of ABCC4 protein |
CTD |
PMID:19371622 |
|
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
|
|
G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
increases expression |
ISO |
allyl alcohol results in increased expression of ABCC5 mRNA; allyl alcohol results in increased expression of ABCC5 protein |
CTD |
PMID:19371622 |
|
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
|
|
G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
decreases expression |
ISO |
allyl alcohol results in decreased expression of ABCC6 mRNA |
CTD |
PMID:19371622 |
|
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
|
|
G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
increases oxidation multiple interactions |
ISO |
ADH1 protein results in increased oxidation of allyl alcohol [ADH1 protein results in increased oxidation of allyl alcohol] which results in increased abundance of Acetone |
CTD |
PMID:11981770 |
|
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
|
|
G |
Afp |
alpha-fetoprotein |
increases expression |
ISO EXP |
allyl alcohol results in increased expression of AFP protein |
CTD |
PMID:61145 PMID:70250 |
|
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
|
|
G |
Bcat1 |
branched chain amino acid transaminase 1 |
increases expression |
EXP |
allyl alcohol results in increased expression of BCAT1 mRNA |
CTD |
PMID:23558518 |
|
NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
allyl alcohol results in increased expression of CCL2 mRNA |
CTD |
PMID:21907259 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
|
|
G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression |
EXP |
allyl alcohol results in increased expression of CYP2B1 protein |
CTD |
PMID:10445401 |
|
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases expression |
ISO |
allyl alcohol results in increased expression of CYP2E1 protein |
CTD |
PMID:11515535 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases expression |
EXP |
allyl alcohol results in decreased expression of CYP3A2 protein |
CTD |
PMID:10445401 |
|
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases secretion increases activity |
ISO EXP |
diisopropyl 1,3-dithiol-2-ylidenemalonate inhibits the reaction [allyl alcohol results in increased activity of GPT protein] allyl alcohol results in increased secretion of GPT protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]; Caffeine promotes the reaction [allyl alcohol results in increased activity of GPT protein]; chelerythrine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]; fomepizole inhibits the reaction [Caffeine promotes the reaction [allyl alcohol results in increased activity of GPT protein]]; Genistein inhibits the reaction [allyl alcohol results in increased secretion of GPT protein]; rottlerin inhibits the reaction [allyl alcohol results in increased secretion of GPT protein] |
CTD |
PMID:3795300 PMID:11394713 PMID:12755590 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
ISO |
allyl alcohol results in increased expression of HAVCR1 mRNA |
CTD |
PMID:21907259 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
|
|
G |
Hsf1 |
heat shock transcription factor 1 |
increases activity |
ISO |
allyl alcohol results in increased activity of HSF1 protein |
CTD |
PMID:34170685 |
|
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
|
|
G |
Il1b |
interleukin 1 beta |
increases expression |
EXP |
allyl alcohol results in increased expression of IL1B mRNA |
CTD |
PMID:15135310 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il6 |
interleukin 6 |
increases expression |
EXP |
allyl alcohol results in increased expression of IL6 mRNA |
CTD |
PMID:15135310 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
|
|
G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
increases expression |
EXP |
allyl alcohol results in increased expression of LMCD1 mRNA |
CTD |
PMID:23558518 |
|
NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
|
|
G |
Mir122 |
microRNA 122 |
increases expression |
EXP |
allyl alcohol results in increased expression of MIR122 mRNA |
CTD |
PMID:23143187 |
|
NCBI chr18:58,758,703...58,758,787
|
|
G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
EXP |
allyl alcohol results in increased expression of NOS2 mRNA |
CTD |
PMID:15135310 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
|
|
G |
Pcolce |
procollagen C-endopeptidase enhancer |
multiple interactions |
EXP |
allyl alcohol results in increased expression of and results in increased secretion of PCOLCE protein |
CTD |
PMID:26396155 |
|
NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
|
|
G |
Prkcd |
protein kinase C, delta |
affects localization increases phosphorylation multiple interactions |
EXP |
allyl alcohol affects the localization of PRKCD protein allyl alcohol results in increased phosphorylation of PRKCD protein fomepizole inhibits the reaction [allyl alcohol affects the localization of PRKCD protein] |
CTD |
PMID:12755590 |
|
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
EXP |
allyl alcohol results in increased expression of PTGS2 mRNA allyl alcohol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:11446826 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions affects localization |
EXP |
15-deoxyprostaglandin J2 inhibits the reaction [allyl alcohol affects the localization of RELA protein] |
CTD |
PMID:14657518 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Slc10a1 |
solute carrier family 10 member 1 |
decreases expression |
ISO |
allyl alcohol results in decreased expression of SLC10A1 mRNA; allyl alcohol results in decreased expression of SLC10A1 protein |
CTD |
PMID:19371622 |
|
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
|
|
G |
Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
increases expression |
ISO |
allyl alcohol results in increased expression of SLCO1A4 protein |
CTD |
PMID:19371622 |
|
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
|
|
G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
decreases expression |
ISO |
allyl alcohol results in decreased expression of SLCO1B2 mRNA; allyl alcohol results in decreased expression of SLCO1B2 protein |
CTD |
PMID:19371622 |
|
NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
|
|
G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
EXP |
allyl alcohol results in increased expression of SPP1 mRNA |
CTD |
PMID:23558518 |
|
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
|
|
G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
allyl alcohol results in increased expression of SRXN1 protein |
CTD |
PMID:27358234 |
|
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
EXP |
allyl alcohol results in increased expression of TGFB1 mRNA Tamoxifen inhibits the reaction [allyl alcohol results in increased expression of TGFB1 mRNA] |
CTD |
PMID:11063159 PMID:18564211 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
|
|
G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
multiple interactions increases expression |
EXP |
Tamoxifen inhibits the reaction [allyl alcohol results in increased expression of TGFBR1 mRNA] |
CTD |
PMID:18564211 |
|
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression |
EXP |
allyl alcohol results in increased expression of TIMP1 mRNA |
CTD |
PMID:23558518 |
|
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
|
|
G |
Tnf |
tumor necrosis factor |
increases expression |
EXP |
allyl alcohol results in increased expression of TNF mRNA |
CTD |
PMID:15135310 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Vnn1 |
vanin 1 |
increases expression |
ISO |
allyl alcohol results in increased expression of VNN1 mRNA |
CTD |
PMID:21907259 |
|
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
|
|
|
G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions |
ISO |
fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]] |
CTD |
PMID:24954032 |
|
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
|
|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]] |
CTD |
PMID:24954032 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Foxo3 |
forkhead box O3 |
multiple interactions |
ISO |
fostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]] |
CTD |
PMID:24954032 |
|
NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
|
|
G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
fostriecin promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]] |
CTD |
PMID:24954032 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
|
|
|
G |
Ar |
androgen receptor |
multiple interactions |
ISO |
ganoderol B binds to and results in decreased activity of AR protein; ganoderol B inhibits the reaction [Dihydrotestosterone binds to AR protein] |
CTD |
PMID:17499997 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
|
|
G |
Klk1c10 |
kallikrein 1-related peptidase C10 |
decreases expression |
ISO |
ganoderol B results in decreased expression of KLK3 mRNA |
CTD |
PMID:17499997 |
|
NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
|
|
G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
decreases activity |
EXP |
ganoderol B results in decreased activity of SRD5A1 protein |
CTD |
PMID:17499997 |
|
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
|
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; geraniol inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] |
CTD |
PMID:31005848 |
|
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
|
|
G |
Acaca |
acetyl-CoA carboxylase alpha |
decreases expression |
ISO |
geraniol results in decreased expression of ACACA mRNA |
CTD |
PMID:26141755 |
|
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
|
|
G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
geraniol inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] |
CTD |
PMID:24752916 PMID:25199698 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACTA2 mRNA] |
CTD |
PMID:26695085 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
|
|
G |
Actl6a |
actin-like 6A |
decreases expression |
ISO |
geraniol results in decreased expression of ACTL6A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:115,492,374...115,508,401
Ensembl chr 2:115,492,285...115,508,401
|
|
G |
Acvr1 |
activin A receptor type 1 |
increases expression |
ISO |
geraniol results in increased expression of ACVR1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
|
|
G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
EXP |
geraniol inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein] |
CTD |
PMID:25679220 PMID:28178614 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
|
|
G |
Aff4 |
ALF transcription elongation factor 4 |
increases expression |
ISO |
geraniol results in increased expression of AFF4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
EXP |
geraniol inhibits the reaction [Fructose results in increased expression of AGER protein] |
CTD |
PMID:25679220 |
|
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
|
|
G |
Ahctf1 |
AT hook containing transcription factor 1 |
decreases expression |
ISO |
geraniol results in decreased expression of AHCTF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:91,481,936...91,536,391
Ensembl chr13:91,481,936...91,536,391
|
|
G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
geraniol results in increased expression of AKR1C1 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
|
|
G |
Ap5z1 |
adaptor related protein complex 5 subunit zeta 1 |
increases expression |
ISO |
geraniol results in increased expression of AP5Z1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511
|
|
G |
Apbb2 |
amyloid beta precursor protein binding family B member 2 |
increases expression |
ISO |
geraniol results in increased expression of APBB2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
|
|
G |
Appl1 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
decreases expression |
ISO |
geraniol results in decreased expression of APPL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
geraniol results in increased expression of ATF3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
|
|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in increased expression of ATF4 protein] |
CTD |
PMID:30141137 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
|
|
G |
Atf6 |
activating transcription factor 6 |
increases expression multiple interactions |
ISO |
geraniol results in increased expression of ATF6 mRNA geraniol inhibits the reaction [Rotenone results in increased expression of ATF6 protein] |
CTD |
PMID:27683099 PMID:30141137 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
|
|
G |
Atg12 |
autophagy related 12 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein] |
CTD |
PMID:30141137 |
|
NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
|
|
G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in decreased expression of ATG5 protein] |
CTD |
PMID:30141137 |
|
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
|
|
G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in decreased expression of ATG7 protein] |
CTD |
PMID:30141137 |
|
NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
|
|
G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
geraniol results in increased expression of BAK1 protein |
CTD |
PMID:12530055 |
|
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of BAX protein] geraniol inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA] geraniol results in increased expression of BAX mRNA; geraniol results in increased expression of BAX protein |
CTD |
PMID:21371438 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 PMID:30506710 PMID:34343525 More...
|
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
|
|
G |
Baz1b |
bromodomain adjacent to zinc finger domain, 1B |
decreases expression |
ISO |
geraniol results in decreased expression of BAZ1B mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
|
|
G |
Baz2b |
bromodomain adjacent to zinc finger domain, 2B |
increases expression |
ISO |
geraniol results in increased expression of BAZ2B mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:44,384,282...44,681,619
Ensembl chr 3:44,385,474...44,592,908
|
|
G |
Bbx |
BBX high mobility group box domain containing |
increases expression |
ISO |
geraniol results in increased expression of BBX mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:50,381,249...50,628,934
Ensembl chr11:50,381,247...50,623,251
|
|
G |
Bcl11a |
BCL11 transcription factor A |
decreases expression |
ISO |
geraniol results in decreased expression of BCL11A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
ISO EXP |
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of BCL2 protein] geraniol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA] geraniol results in decreased expression of BCL2 mRNA; geraniol results in decreased expression of BCL2 protein geraniol results in increased expression of BCL2 protein |
CTD |
PMID:21371438 PMID:21445532 PMID:22760862 PMID:24768735 PMID:29050341 PMID:29745075 PMID:30506710 PMID:34343525 More...
|
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA] |
CTD |
PMID:26695085 PMID:35608392 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
|
|
G |
Bcl2l2 |
Bcl2-like 2 |
decreases expression |
ISO |
geraniol results in decreased expression of BCL2L2 protein |
CTD |
PMID:21371438 |
|
NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
|
|
G |
Bcl6 |
BCL6, transcription repressor |
increases expression |
ISO |
geraniol results in increased expression of BCL6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
|
|
G |
Bclaf1 |
BCL2-associated transcription factor 1 |
decreases expression |
ISO |
geraniol results in decreased expression of BCLAF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BDNF protein] |
CTD |
PMID:23943375 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
|
|
G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
geraniol results in decreased expression of BIRC5 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
|
|
G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
increases expression |
ISO |
geraniol results in increased expression of BMAL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
|
|
G |
Bmp6 |
bone morphogenetic protein 6 |
increases expression |
ISO |
geraniol results in increased expression of BMP6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
|
|
G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression |
ISO |
geraniol results in increased expression of BNIP3 protein |
CTD |
PMID:21371438 |
|
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
|
|
G |
Brca1 |
BRCA1, DNA repair associated |
decreases expression |
ISO |
geraniol results in decreased expression of BRCA1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
|
|
G |
Brca2 |
BRCA2, DNA repair associated |
decreases expression |
ISO |
geraniol results in decreased expression of BRCA2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
|
|
G |
Btf3 |
basic transcription factor 3 |
decreases expression |
ISO |
geraniol results in decreased expression of BTF3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
|
|
G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
decreases expression |
ISO |
geraniol results in decreased expression of BUB1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
|
|
G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
ISO |
geraniol results in decreased expression of BUB1B mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression |
EXP ISO |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP3 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein] geraniol results in increased activity of CASP3 protein geraniol results in increased expression of CASP3 mRNA; geraniol results in increased expression of CASP3 protein geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CASP3 protein] geraniol results in increased expression of CASP3 protein modified form |
CTD |
PMID:21371438 PMID:21907755 PMID:22509279 PMID:24875281 PMID:26154255 PMID:26165751 PMID:26364502 PMID:26695085 PMID:29050341 PMID:30506710 PMID:34343525 More...
|
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
|
|
G |
Casp8 |
caspase 8 |
multiple interactions increases expression |
EXP ISO |
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA] geraniol results in increased expression of CASP8 mRNA; geraniol results in increased expression of CASP8 protein |
CTD |
PMID:21907755 PMID:30506710 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
|
|
G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
EXP ISO |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CASP9 protein]; geraniol inhibits the reaction [Doxorubicin results in increased cleavage of CASP9 protein] geraniol results in increased expression of CASP9 mRNA; geraniol results in increased expression of CASP9 protein geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein] |
CTD |
PMID:21907755 PMID:22509279 PMID:24768735 PMID:26364502 PMID:26695085 PMID:30506710 PMID:34343525 More...
|
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
|
|
G |
Cat |
catalase |
multiple interactions decreases activity increases activity |
ISO EXP |
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CAT protein]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein] geraniol results in decreased activity of CAT protein geraniol results in increased activity of CAT protein geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of CAT protein]; geraniol inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein] |
CTD |
PMID:21907755 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 PMID:24768735 PMID:25574396 PMID:26364502 PMID:28178614 PMID:32119866 PMID:35608392 More...
|
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Cbfa2t2 |
CBFA2/RUNX1 partner transcriptional co-repressor 2 |
increases expression |
ISO |
geraniol results in increased expression of CBFA2T2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:142,936,945...143,043,205
Ensembl chr 3:142,936,985...143,043,197
|
|
G |
Cbfb |
core-binding factor subunit beta |
decreases expression |
ISO |
geraniol results in decreased expression of CBFB mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases secretion |
ISO |
geraniol results in increased secretion of CCL4 protein |
CTD |
PMID:30806763 |
|
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
|
|
G |
Ccna2 |
cyclin A2 |
decreases expression |
ISO |
geraniol results in decreased expression of CCNA2 mRNA; geraniol results in decreased expression of CCNA2 protein |
CTD |
PMID:17138864 PMID:27683099 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
|
|
G |
Ccnb1 |
cyclin B1 |
decreases expression |
ISO |
geraniol results in decreased expression of CCNB1 protein |
CTD |
PMID:17138864 PMID:21371438 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
|
|
G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
geraniol results in decreased expression of CCND1 protein |
CTD |
PMID:15450939 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
geraniol results in increased expression of CD86 protein |
CTD |
PMID:30806763 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
|
|
G |
Cdc20 |
cell division cycle 20 |
decreases expression |
ISO |
geraniol results in decreased expression of CDC20 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
|
|
G |
Cdc25a |
cell division cycle 25A |
decreases expression |
ISO |
geraniol results in decreased expression of CDC25A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
|
|
G |
Cdc25c |
cell division cycle 25C |
decreases expression |
ISO |
geraniol results in decreased expression of CDC25C mRNA |
CTD |
PMID:27683099 |
|
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
|
|
G |
Cdc45 |
cell division cycle 45 |
decreases expression |
ISO |
geraniol results in decreased expression of CDC45 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
|
|
G |
Cdc7 |
cell division cycle 7 |
decreases expression |
ISO |
geraniol results in decreased expression of CDC7 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
|
|
G |
Cdh1 |
cadherin 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] |
CTD |
PMID:28428697 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
geraniol results in decreased expression of CDK1 protein |
CTD |
PMID:21371438 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
|
|
G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression multiple interactions |
ISO |
geraniol results in decreased expression of CDK2 mRNA; geraniol results in decreased expression of CDK2 protein geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein]; geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein] |
CTD |
PMID:15450939 PMID:17138864 PMID:27683099 |
|
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
|
|
G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
geraniol results in decreased expression of CDK4 protein |
CTD |
PMID:15450939 PMID:21371438 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions increases response to substance |
ISO |
geraniol results in increased expression of CDKN1A protein geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] CDKN1A protein results in increased susceptibility to geraniol |
CTD |
PMID:17138864 PMID:21371438 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
|
|
G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression multiple interactions increases response to substance |
ISO |
geraniol results in increased expression of CDKN1B protein geraniol promotes the reaction [CDKN1B protein binds to and results in decreased activity of CDK2 protein] CDKN1B protein results in increased susceptibility to geraniol |
CTD |
PMID:17138864 PMID:21371438 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
|
|
G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
decreases expression |
ISO |
geraniol results in decreased expression of CDKN2C mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
|
|
G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
ISO |
geraniol results in decreased expression of CDKN3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
|
|
G |
Cdt1 |
chromatin licensing and DNA replication factor 1 |
decreases expression |
ISO |
geraniol results in decreased expression of CDT1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
|
|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
geraniol results in increased expression of CEBPB mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
|
|
G |
Cebpg |
CCAAT/enhancer binding protein gamma |
increases expression |
ISO |
geraniol results in increased expression of CEBPG mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
|
|
G |
Cenpe |
centromere protein E |
decreases expression |
ISO |
geraniol results in decreased expression of CENPE mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
|
|
G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
geraniol results in decreased expression of CENPF mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
|
|
G |
Chek1 |
checkpoint kinase 1 |
decreases expression |
ISO |
geraniol results in decreased expression of CHEK1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
|
|
G |
Cit |
citron rho-interacting serine/threonine kinase |
decreases expression |
ISO |
geraniol results in decreased expression of CIT mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
|
|
G |
Ckm |
creatine kinase, M-type |
multiple interactions |
EXP |
geraniol inhibits the reaction [Doxorubicin results in increased activity of CKM protein] |
CTD |
PMID:34343525 |
|
NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
|
|
G |
Cnbp |
CCHC-type zinc finger, nucleic acid binding protein |
decreases expression |
ISO |
geraniol results in decreased expression of CNBP mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
|
|
G |
Cnga2 |
cyclic nucleotide gated channel subunit alpha 2 |
multiple interactions |
ISO |
CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] |
CTD |
PMID:29070885 |
|
NCBI chr X:149,696,999...149,715,051
Ensembl chr X:149,696,997...149,715,051
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA] |
CTD |
PMID:26695085 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
|
|
G |
Cox7c |
cytochrome c oxidase subunit 7C |
multiple interactions |
ISO |
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA] |
CTD |
PMID:24768735 |
|
NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
|
|
G |
Creb3 |
cAMP responsive element binding protein 3 |
increases expression |
ISO |
geraniol results in increased expression of CREB3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
|
|
G |
Creb3l2 |
cAMP responsive element binding protein 3-like 2 |
increases expression |
ISO |
geraniol results in increased expression of CREB3L2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
|
|
G |
Crp |
C-reactive protein |
multiple interactions |
EXP |
geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein] |
CTD |
PMID:35608392 |
|
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
|
|
G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein] |
CTD |
PMID:26165751 PMID:28428697 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
|
|
G |
Ctsd |
cathepsin D |
multiple interactions |
EXP |
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CTSD protein] |
CTD |
PMID:23499697 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
|
|
G |
Cyb5a |
cytochrome b5 type A |
multiple interactions |
EXP |
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of CYB5A protein] |
CTD |
PMID:23499697 |
|
NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
|
|
G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
ISO |
geraniol inhibits the reaction [Dietary Fats results in increased expression of CYBB protein] geraniol inhibits the reaction [Palmitic Acid results in increased expression of CYBB protein] |
CTD |
PMID:27107694 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
|
|
G |
Cyc1 |
cytochrome c-1 |
multiple interactions |
ISO |
geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein] |
CTD |
PMID:24768735 |
|
NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases metabolic processing |
ISO |
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP1A1 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite |
CTD |
PMID:18824010 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol |
CTD |
PMID:18824010 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions increases metabolic processing |
ISO |
[[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP2B6 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; geraniol inhibits the reaction [CYP2B6 protein results in increased hydrolysis of Bupropion] |
CTD |
PMID:18611395 PMID:18824010 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP ISO |
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP2E1 protein] [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol |
CTD |
PMID:18824010 PMID:26695085 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
|
|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
increases metabolic processing multiple interactions |
ISO |
CYP3A5 protein results in increased metabolism of geraniol [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of citral metabolite; [[CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite; [CYP1A1 protein co-treated with CYP1B1 protein co-treated with CYP2B6 protein co-treated with CYP2E1 protein co-treated with CYP3A5 protein] results in increased metabolism of geraniol; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of citral; [CYP3A5 protein results in increased metabolism of geraniol] which results in increased chemical synthesis of geraniol metabolite |
CTD |
PMID:18824010 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
|
|
G |
Dbf4 |
DBF4-CDC7 kinase regulatory subunit |
decreases expression |
ISO |
geraniol results in decreased expression of DBF4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
ISO |
geraniol results in increased expression of DDIT3 mRNA geraniol inhibits the reaction [Rotenone results in increased expression of DDIT3 protein] |
CTD |
PMID:27683099 PMID:30141137 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
|
|
G |
Dek |
DEK proto-oncogene |
decreases expression |
ISO |
geraniol results in decreased expression of DEK mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
|
|
G |
Dmtf1 |
cyclin D binding myb-like transcription factor 1 |
increases expression |
ISO |
geraniol results in increased expression of DMTF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
|
|
G |
Dnajc1 |
DnaJ heat shock protein family (Hsp40) member C1 |
increases expression |
ISO |
geraniol results in increased expression of DNAJC1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988
|
|
G |
Dr1 |
down-regulator of transcription 1 |
decreases expression |
ISO |
geraniol results in decreased expression of DR1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
|
|
G |
Dtymk |
deoxythymidylate kinase |
decreases expression |
ISO |
geraniol results in decreased expression of DTYMK mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
|
|
G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
geraniol results in decreased expression of E2F1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
|
|
G |
E2f8 |
E2F transcription factor 8 |
decreases expression |
ISO |
geraniol results in decreased expression of E2F8 mRNA; geraniol results in decreased expression of E2F8 protein |
CTD |
PMID:27683099 |
|
NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
|
|
G |
Ehf |
ets homologous factor |
decreases expression |
ISO |
geraniol results in decreased expression of EHF mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
|
|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein] |
CTD |
PMID:30141137 |
|
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in increased expression of EIF2S1 protein] |
CTD |
PMID:30141137 |
|
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
|
|
G |
Elavl2 |
ELAV like RNA binding protein 2 |
decreases expression |
ISO |
geraniol results in decreased expression of ELAVL2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097
|
|
G |
Elf1 |
E74 like ETS transcription factor 1 |
increases expression |
ISO |
geraniol results in increased expression of ELF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
|
|
G |
Elk4 |
ETS transcription factor ELK4 |
increases expression |
ISO |
geraniol results in increased expression of ELK4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
|
|
G |
Erc1 |
ELKS/RAB6-interacting/CAST family member 1 |
increases expression |
ISO |
geraniol results in increased expression of ERC1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639
|
|
G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in increased expression of ERN1 protein] |
CTD |
PMID:30141137 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
|
|
G |
Espl1 |
extra spindle pole bodies like 1, separase |
decreases expression |
ISO |
geraniol results in decreased expression of ESPL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
|
|
G |
Esr1 |
estrogen receptor 1 |
affects binding multiple interactions |
ISO |
geraniol binds to ESR1 protein geraniol inhibits the reaction [Estradiol binds to ESR1 protein] |
CTD |
PMID:12495555 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
|
|
G |
Esr2 |
estrogen receptor 2 |
affects binding multiple interactions |
ISO |
geraniol binds to ESR2 protein geraniol inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:12495555 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
|
|
G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
increases expression |
ISO |
geraniol results in increased expression of ETS2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
|
|
G |
Etv1 |
ETS variant transcription factor 1 |
decreases expression |
ISO |
geraniol results in decreased expression of ETV1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
|
|
G |
Ewsr1 |
EWS RNA-binding protein 1 |
decreases expression |
ISO |
geraniol results in decreased expression of EWSR1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
|
|
G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
decreases expression |
ISO |
geraniol results in decreased expression of EZH2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
|
|
G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO |
geraniol results in increased expression of FABP4 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
|
|
G |
Fads1 |
fatty acid desaturase 1 |
multiple interactions decreases activity |
ISO |
[geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid; [geraniol results in decreased activity of FADS1 protein] which results in decreased metabolism of 8,11,14-Eicosatrienoic Acid |
CTD |
PMID:16462894 |
|
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
|
|
G |
Fancg |
FA complementation group G |
decreases expression |
ISO |
geraniol results in decreased expression of FANCG mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
|
|
G |
Fasn |
fatty acid synthase |
multiple interactions |
EXP |
geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA] |
CTD |
PMID:26695085 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
|
|
G |
Fbxo5 |
F-box protein 5 |
decreases expression |
ISO |
geraniol results in decreased expression of FBXO5 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
geraniol results in increased expression of FOS mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
decreases expression |
ISO |
geraniol results in decreased expression of FOSL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
|
|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
geraniol results in increased expression of FOSL2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
|
|
G |
Foxa2 |
forkhead box A2 |
decreases expression |
ISO |
geraniol results in decreased expression of FOXA2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
|
|
G |
Foxj3 |
forkhead box J3 |
increases expression |
ISO |
geraniol results in increased expression of FOXJ3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489
|
|
G |
Foxm1 |
forkhead box M1 |
decreases expression |
ISO |
geraniol results in decreased expression of FOXM1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
|
|
G |
Foxo4 |
forkhead box O4 |
increases expression |
ISO |
geraniol results in increased expression of FOXO4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
|
|
G |
Fst |
follistatin |
increases expression |
ISO |
geraniol results in increased expression of FST mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
|
|
G |
Fubp1 |
far upstream element binding protein 1 |
decreases expression |
ISO |
geraniol results in decreased expression of FUBP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions |
ISO EXP |
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein] geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein] |
CTD |
PMID:23399806 PMID:28330423 |
|
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
|
|
G |
Gatad1 |
GATA zinc finger domain containing 1 |
increases expression |
ISO |
geraniol results in increased expression of GATAD1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107
|
|
G |
Gbx2 |
gastrulation brain homeobox 2 |
decreases expression |
ISO |
geraniol results in decreased expression of GBX2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
|
|
G |
Gcg |
glucagon |
multiple interactions increases secretion |
ISO |
9-(tetrahydro-2-furyl)-adenine inhibits the reaction [geraniol results in increased secretion of GCG protein]; CNGA2 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein]; OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] |
CTD |
PMID:29070885 |
|
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GDNF protein] |
CTD |
PMID:23943375 |
|
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
|
|
G |
Gmnn |
geminin, DNA replication inhibitor |
decreases expression |
ISO |
geraniol results in decreased expression of GMNN mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
|
|
G |
Gna15 |
G protein subunit alpha 15 |
increases response to substance multiple interactions |
ISO |
GNA15 protein results in increased susceptibility to geraniol [GNA15 protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein |
CTD |
PMID:15598656 |
|
NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
|
|
G |
Gnal |
G protein subunit alpha L |
increases response to substance multiple interactions |
ISO |
GNAL protein results in increased susceptibility to geraniol [GNAL protein results in increased susceptibility to geraniol] which results in increased activity of OR1A1B protein; GNAL mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] |
CTD |
PMID:15598656 PMID:29070885 |
|
NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
|
|
G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Doxorubicin results in increased activity of GOT1 protein] |
CTD |
PMID:34343525 |
|
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
geraniol inhibits the reaction [Doxorubicin results in increased activity of GPT protein] |
CTD |
PMID:34343525 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA] |
CTD |
PMID:22509279 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP |
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] |
CTD |
PMID:26165751 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
|
|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity |
ISO EXP |
geraniol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein] geraniol results in decreased activity of GSR protein [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; geraniol inhibits the reaction [2-Acetylaminofluorene results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein] |
CTD |
PMID:22509279 PMID:22760862 PMID:23033690 PMID:23399806 PMID:24752916 PMID:26364502 PMID:28817314 More...
|
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein] |
CTD |
PMID:27046949 |
|
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
|
|
G |
Gtf2b |
general transcription factor IIB |
increases expression |
ISO |
geraniol results in increased expression of GTF2B mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
|
|
G |
Gtf2h1 |
general transcription factor IIH subunit 1 |
increases expression |
ISO |
geraniol results in increased expression of GTF2H1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455
|
|
G |
Gtf2ird1 |
GTF2I repeat domain containing 1 |
increases expression |
ISO |
geraniol results in increased expression of GTF2IRD1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
|
|
G |
Gtf3a |
general transcription factor III A |
decreases expression |
ISO |
geraniol results in decreased expression of GTF3A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690
|
|
G |
Gtf3c1 |
general transcription factor IIIC subunit 1 |
increases expression |
ISO |
geraniol results in increased expression of GTF3C1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:180,203,995...180,270,201
Ensembl chr 1:180,203,995...180,270,201
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein] |
CTD |
PMID:21907755 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
|
|
G |
Hbb |
hemoglobin subunit beta |
multiple interactions |
EXP |
geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]] |
CTD |
PMID:25679220 |
|
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
|
|
G |
Hbp1 |
HMG-box transcription factor 1 |
increases expression |
ISO |
geraniol results in increased expression of HBP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
|
|
G |
Hivep1 |
HIVEP zinc finger 1 |
increases expression |
ISO |
geraniol results in increased expression of HIVEP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:22,585,016...22,714,517
Ensembl chr17:22,585,016...22,711,956
|
|
G |
Hlf |
HLF transcription factor, PAR bZIP family member |
decreases expression |
ISO |
geraniol results in decreased expression of HLF mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
|
|
G |
Hmbox1 |
homeobox containing 1 |
increases expression |
ISO |
geraniol results in increased expression of HMBOX1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323
|
|
G |
Hmg20b |
high mobility group 20 B |
decreases expression |
ISO |
geraniol results in decreased expression of HMG20B mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640
|
|
G |
Hmgb2 |
high mobility group box 2 |
decreases expression |
ISO |
geraniol results in decreased expression of HMGB2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
|
|
G |
Hmgb3 |
high mobility group box 3 |
decreases expression |
ISO |
geraniol results in decreased expression of HMGB3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression decreases expression affects expression decreases activity |
ISO |
geraniol results in increased expression of HMGCR mRNA geraniol results in decreased expression of HMGCR protein geraniol affects the expression of HMGCR mRNA geraniol results in decreased activity of HMGCR protein |
CTD |
PMID:12477733 PMID:15450939 PMID:16462894 PMID:23668785 PMID:24875281 PMID:26141755 More...
|
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
|
G |
Hmgxb3 |
HMG-box containing 3 |
increases expression |
ISO |
geraniol results in increased expression of HMGXB3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr18:54,590,558...54,638,050
Ensembl chr18:54,590,560...54,638,155
|
|
G |
Hmgxb4 |
HMG-box containing 4 |
decreases expression |
ISO |
geraniol results in decreased expression of HMGXB4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
geraniol results in increased expression of HMOX1 mRNA geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of HMOX1 protein] geraniol results in increased expression of HMOX1 protein |
CTD |
PMID:20713136 PMID:28334550 PMID:30806763 PMID:34343525 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hnrnpab |
heterogeneous nuclear ribonucleoprotein A/B |
decreases expression |
ISO |
geraniol results in decreased expression of HNRNPAB mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
|
|
G |
Hoxa5 |
homeo box A5 |
increases expression |
ISO |
geraniol results in increased expression of HOXA5 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234
|
|
G |
Hoxb13 |
homeo box B13 |
decreases expression |
ISO |
geraniol results in decreased expression of HOXB13 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777
|
|
G |
Hoxc6 |
homeo box C6 |
increases expression |
ISO |
geraniol results in increased expression of HOXC6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein |
CTD |
PMID:22760862 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
|
|
G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
decreases expression |
ISO |
geraniol results in decreased expression of HSPA2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
|
|
G |
Htr3a |
5-hydroxytryptamine receptor 3A |
decreases activity |
ISO |
geraniol results in decreased activity of HTR3A protein |
CTD |
PMID:26456648 |
|
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO EXP |
geraniol inhibits the reaction [Dietary Fats results in increased expression of ICAM1 protein] geraniol inhibits the reaction [Palmitic Acid results in increased expression of ICAM1 protein] geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein] |
CTD |
PMID:26165751 PMID:27107694 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
|
|
G |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
geraniol results in increased expression of ID1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
|
|
G |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
geraniol results in increased expression of ID3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein] |
CTD |
PMID:26973525 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Il10 |
interleukin 10 |
increases expression multiple interactions |
ISO |
geraniol results in increased expression of IL10 protein geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL10 protein] |
CTD |
PMID:24934659 PMID:26973525 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
|
|
G |
Il16 |
interleukin 16 |
increases secretion |
ISO |
geraniol results in increased secretion of IL16 protein |
CTD |
PMID:30806763 |
|
NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
|
|
G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein] |
CTD |
PMID:26973525 |
|
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
|
|
G |
Il18 |
interleukin 18 |
multiple interactions |
ISO EXP |
geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]] geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein] |
CTD |
PMID:21430599 PMID:34343525 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression |
ISO |
geraniol results in increased expression of IL1A protein |
CTD |
PMID:19878710 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP ISO |
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of IL1B protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; geraniol inhibits the reaction [ovalbumin-alum results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]] geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA] |
CTD |
PMID:20304105 PMID:21282739 PMID:21430599 PMID:23399806 PMID:25679220 PMID:26165751 PMID:26190278 PMID:26973525 PMID:28397014 PMID:29050341 PMID:30254419 PMID:30550845 PMID:31005848 PMID:34343525 More...
|
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
|
G |
Il1r2 |
interleukin 1 receptor type 2 |
increases expression |
ISO |
geraniol results in increased expression of IL1R2 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
|
|
G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
ISO EXP |
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; geraniol inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA] geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein] geraniol results in increased expression of IL6 mRNA |
CTD |
PMID:23399806 PMID:26190278 PMID:26695085 PMID:26973525 PMID:27107694 PMID:28358702 PMID:29050341 PMID:30254419 PMID:31005848 PMID:35608392 More...
|
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
|
|
G |
Il7r |
interleukin 7 receptor |
increases expression |
ISO |
geraniol results in increased expression of IL7R mRNA |
CTD |
PMID:20713136 |
|
NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
|
|
G |
Ilf2 |
interleukin enhancer binding factor 2 |
decreases expression |
ISO |
geraniol results in decreased expression of ILF2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337
|
|
G |
Ins1 |
insulin 1 |
increases secretion multiple interactions |
ISO EXP |
geraniol results in increased secretion of INS1 protein geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein] |
CTD |
PMID:28330423 PMID:29070885 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
|
G |
Irf1 |
interferon regulatory factor 1 |
increases expression |
ISO |
geraniol results in increased expression of IRF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
|
|
G |
Irf6 |
interferon regulatory factor 6 |
increases expression |
ISO |
geraniol results in increased expression of IRF6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386
|
|
G |
Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
geraniol results in increased expression of IRF7 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
|
|
G |
Irf9 |
interferon regulatory factor 9 |
increases expression |
ISO |
geraniol results in increased expression of IRF9 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
|
|
G |
Jarid2 |
jumonji and AT-rich interaction domain containing 2 |
increases expression |
ISO |
geraniol results in increased expression of JARID2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
|
|
G |
Jmjd1c |
jumonji domain containing 1C |
increases expression |
ISO |
geraniol results in increased expression of JMJD1C mRNA |
CTD |
PMID:27683099 |
|
NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
geraniol results in increased expression of JUN mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
|
|
G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
geraniol results in increased expression of JUNB mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
|
|
G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
geraniol results in increased expression of JUND mRNA |
CTD |
PMID:27683099 |
|
NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
|
|
G |
Kdr |
kinase insert domain receptor |
decreases expression |
ISO |
geraniol results in decreased expression of KDR protein |
CTD |
PMID:26154255 |
|
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
|
|
G |
Khdrbs1 |
KH RNA binding domain containing, signal transduction associated 1 |
decreases expression |
ISO |
geraniol results in decreased expression of KHDRBS1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180
|
|
G |
Kif11 |
kinesin family member 11 |
decreases expression |
ISO |
geraniol results in decreased expression of KIF11 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
|
|
G |
Kif15 |
kinesin family member 15 |
decreases expression |
ISO |
geraniol results in decreased expression of KIF15 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
|
|
G |
Kif22 |
kinesin family member 22 |
decreases expression |
ISO |
geraniol results in decreased expression of KIF22 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
|
|
G |
Kif23 |
kinesin family member 23 |
decreases expression |
ISO |
geraniol results in decreased expression of KIF23 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
|
|
G |
Kif2c |
kinesin family member 2C |
decreases expression |
ISO |
geraniol results in decreased expression of KIF2C mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
|
|
G |
Klf11 |
KLF transcription factor 11 |
increases expression |
ISO |
geraniol results in increased expression of KLF11 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
|
|
G |
Klf13 |
KLF transcription factor 13 |
increases expression |
ISO |
geraniol results in increased expression of KLF13 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:117,505,857...117,536,626
Ensembl chr 1:117,503,602...117,551,227
|
|
G |
Klf3 |
KLF transcription factor 3 |
increases expression |
ISO |
geraniol results in increased expression of KLF3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:43,474,767...43,505,801
Ensembl chr14:43,474,767...43,497,209
|
|
G |
Klf4 |
KLF transcription factor 4 |
increases expression |
ISO |
geraniol results in increased expression of KLF4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
|
|
G |
Klf5 |
KLF transcription factor 5 |
increases expression |
ISO |
geraniol results in increased expression of KLF5 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
|
|
G |
Klf6 |
KLF transcription factor 6 |
increases expression |
ISO |
geraniol results in increased expression of KLF6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
|
|
G |
Klf7 |
KLF transcription factor 7 |
increases expression |
ISO |
geraniol results in increased expression of KLF7 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
|
|
G |
Kntc1 |
kinetochore associated 1 |
decreases expression |
ISO |
geraniol results in decreased expression of KNTC1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
|
|
G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 4:178,185,418...178,218,484
|
|
G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
geraniol results in increased expression of LDLR mRNA |
CTD |
PMID:26141755 |
|
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
|
|
G |
Lif |
LIF, interleukin 6 family cytokine |
decreases expression |
ISO |
geraniol results in decreased expression of LIF protein |
CTD |
PMID:19878710 |
|
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
|
|
G |
Lztfl1 |
leucine zipper transcription factor-like 1 |
increases expression |
ISO |
geraniol results in increased expression of LZTFL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192
|
|
G |
Lztr1 |
leucine zipper like post translational regulator 1 |
increases expression |
ISO |
geraniol results in increased expression of LZTR1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633
|
|
G |
Mad2l1 |
mitotic arrest deficient 2 like 1 |
decreases expression |
ISO |
geraniol results in decreased expression of MAD2L1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
|
|
G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
geraniol results in increased expression of MAFF mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
|
|
G |
Mafg |
MAF bZIP transcription factor G |
increases expression |
ISO |
geraniol results in increased expression of MAFG mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
|
|
G |
Maob |
monoamine oxidase B |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of MAOB protein] |
CTD |
PMID:24103762 |
|
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
|
|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein] geraniol results in decreased phosphorylation of MAPK1 protein |
CTD |
PMID:12388655 PMID:22760862 PMID:26154255 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
ISO EXP |
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein] geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein] geraniol results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:12388655 PMID:22760862 PMID:26154255 PMID:35608392 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:35608392 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
|
|
G |
Mcm2 |
minichromosome maintenance complex component 2 |
decreases expression |
ISO |
geraniol results in decreased expression of MCM2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
|
|
G |
Mef2a |
myocyte enhancer factor 2a |
increases expression |
ISO |
geraniol results in increased expression of MEF2A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
|
|
G |
Men1 |
menin 1 |
increases expression |
ISO |
geraniol results in increased expression of MEN1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
|
|
G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
ISO |
geraniol results in decreased expression of MKI67 mRNA geraniol results in decreased expression of MKI67 protein |
CTD |
PMID:26154255 PMID:27683099 |
|
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP2 mRNA] |
CTD |
PMID:35608392 |
|
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
|
|
G |
Mmp3 |
matrix metallopeptidase 3 |
increases expression |
ISO |
geraniol results in increased expression of MMP3 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA] |
CTD |
PMID:35608392 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
|
|
G |
Mnt |
MAX network transcriptional repressor |
increases expression |
ISO |
geraniol results in increased expression of MNT mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835
|
|
G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO EXP |
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein] geraniol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MPO protein]; geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; geraniol inhibits the reaction [Ethanol results in increased expression of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein] |
CTD |
PMID:24337826 PMID:26165751 PMID:26190278 PMID:30550845 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
|
|
G |
Mtor |
mechanistic target of rapamycin kinase |
decreases activity multiple interactions |
ISO |
geraniol results in decreased activity of MTOR protein geraniol inhibits the reaction [Rotenone results in increased phosphorylation of MTOR protein] |
CTD |
PMID:22200837 PMID:30141137 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
|
|
G |
Mvk |
mevalonate kinase |
multiple interactions |
ISO |
geraniol inhibits the reaction [[MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of IL1B protein]; geraniol inhibits the reaction [MVK gene mutant form results in increased susceptibility to Lipopolysaccharides] |
CTD |
PMID:20304105 |
|
NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882
|
|
G |
Mxd1 |
max dimerization protein 1 |
increases expression |
ISO |
geraniol results in increased expression of MXD1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
|
|
G |
Mxd4 |
Max dimerization protein 4 |
increases expression |
ISO |
geraniol results in increased expression of MXD4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221
|
|
G |
Mxi1 |
MAX interactor 1, dimerization protein |
increases expression |
ISO |
geraniol results in increased expression of MXI1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
|
|
G |
Myb |
MYB proto-oncogene, transcription factor |
decreases expression |
ISO |
geraniol results in decreased expression of MYB mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
|
|
G |
Mybl1 |
MYB proto-oncogene like 1 |
decreases expression |
ISO |
geraniol results in decreased expression of MYBL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
|
|
G |
Mybl2 |
MYB proto-oncogene like 2 |
decreases expression |
ISO |
geraniol results in decreased expression of MYBL2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
|
|
G |
Myo6 |
myosin VI |
increases expression |
ISO |
geraniol results in increased expression of MYO6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
|
|
G |
Nasp |
nuclear autoantigenic sperm protein |
decreases expression |
ISO |
geraniol results in decreased expression of NASP mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
|
|
G |
Ncaph |
non-SMC condensin I complex, subunit H |
decreases expression |
ISO |
geraniol results in decreased expression of NCAPH mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
|
|
G |
Ncor1 |
nuclear receptor co-repressor 1 |
increases expression |
ISO |
geraniol results in increased expression of NCOR1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
|
|
G |
Ndp |
norrin cystine knot growth factor NDP |
decreases expression |
ISO |
geraniol results in decreased expression of NDP mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:5,796,487...5,820,934
Ensembl chr X:5,796,487...5,820,934
|
|
G |
Nek2 |
NIMA-related kinase 2 |
decreases expression |
ISO |
geraniol results in decreased expression of NEK2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
|
|
G |
Nfat5 |
nuclear factor of activated T-cells 5 |
increases expression |
ISO |
geraniol results in increased expression of NFAT5 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
|
|
G |
Nfe2l1 |
NFE2 like bZIP transcription factor 1 |
increases expression |
ISO |
geraniol results in increased expression of NFE2L1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
ISO EXP |
geraniol results in increased expression of NFE2L2 mRNA geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 mRNA]; geraniol promotes the reaction [Doxorubicin results in increased expression of NFE2L2 protein] geraniol results in increased expression of NFE2L2 protein |
CTD |
PMID:27683099 PMID:28334550 PMID:34343525 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
|
|
G |
Nfil3 |
nuclear factor, interleukin 3 regulated |
increases expression |
ISO |
geraniol results in increased expression of NFIL3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein] |
CTD |
PMID:21907755 PMID:26165751 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO EXP |
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKBIA protein modified form]; geraniol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] geraniol inhibits the reaction [Doxorubicin results in increased expression of and results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:20506077 PMID:26190278 PMID:29050341 PMID:30550845 PMID:34343525 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
|
|
G |
Nfyb |
nuclear transcription factor Y subunit beta |
decreases expression |
ISO |
geraniol results in decreased expression of NFYB mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
EXP ISO |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of NOS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of NOS2 protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NOS2 protein] geraniol results in decreased expression of NOS2 mRNA; geraniol results in decreased expression of NOS2 protein geraniol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] |
CTD |
PMID:20506077 PMID:22509279 PMID:26190278 PMID:26364502 PMID:26695085 PMID:28397014 PMID:29050341 More...
|
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
|
|
G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Palmitic Acid results in increased expression of NOX1 protein] |
CTD |
PMID:27107694 |
|
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
|
|
G |
Npm1 |
nucleophosmin 1 |
decreases expression |
ISO |
geraniol results in decreased expression of NPM1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in decreased activity of NQO1 protein]; geraniol inhibits the reaction [Doxorubicin results in decreased expression of NQO1 protein] |
CTD |
PMID:23499697 PMID:34343525 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
|
|
G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
increases expression |
ISO |
geraniol results in increased expression of NR1D1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
|
|
G |
Nr1d2 |
nuclear receptor subfamily 1, group D, member 2 |
increases expression |
ISO |
geraniol results in increased expression of NR1D2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
|
|
G |
Nr2f1 |
nuclear receptor subfamily 2, group F, member 1 |
decreases expression |
ISO |
geraniol results in decreased expression of NR2F1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
increases expression |
ISO |
geraniol results in increased expression of NR3C1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
|
|
G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
increases expression |
ISO |
geraniol results in increased expression of NR4A2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
|
|
G |
Nsd2 |
nuclear receptor binding SET domain protein 2 |
decreases expression |
ISO |
geraniol results in decreased expression of NSD2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641
|
|
G |
Nusap1 |
nucleolar and spindle associated protein 1 |
decreases expression |
ISO |
geraniol results in decreased expression of NUSAP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
|
|
G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions decreases activity |
ISO |
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein] geraniol results in decreased activity of ODC1 protein |
CTD |
PMID:11408542 PMID:22760862 |
|
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
|
|
G |
Ogg1 |
8-oxoguanine DNA glycosylase |
multiple interactions |
EXP |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein] |
CTD |
PMID:22509279 |
|
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
|
|
G |
Or1a1 |
olfactory receptor family 1 subfamily A member 1 |
multiple interactions |
ISO |
OR1A1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] |
CTD |
PMID:29070885 |
|
NCBI chr10:59,058,941...59,059,879
Ensembl chr10:59,052,828...59,060,676
|
|
G |
Or1ad5 |
olfactory receptor family 1 subfamily AD member 5 |
multiple interactions |
ISO |
OR1G1 mRNA promotes the reaction [geraniol results in increased secretion of GCG protein] |
CTD |
PMID:29070885 |
|
NCBI chr10:35,307,662...35,308,573
Ensembl chr10:35,304,703...35,308,919
|
|
G |
Pa2g4 |
proliferation-associated 2G4 |
decreases expression |
ISO |
geraniol results in decreased expression of PA2G4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
|
|
G |
Pbx1 |
PBX homeobox 1 |
decreases expression |
ISO |
geraniol results in decreased expression of PBX1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
|
|
G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions decreases expression |
EXP ISO |
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PCNA protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein]; geraniol inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] geraniol results in decreased expression of PCNA protein |
CTD |
PMID:21907755 PMID:26154255 PMID:26364502 PMID:27046949 PMID:28428697 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
|
|
G |
Pgr |
progesterone receptor |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein] |
CTD |
PMID:28428697 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
|
|
G |
Phb1 |
prohibitin 1 |
decreases expression multiple interactions |
ISO EXP |
geraniol results in decreased expression of PHB1 mRNA geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PHB1 protein] |
CTD |
PMID:26695085 PMID:27683099 |
|
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
|
|
G |
Phf1 |
PHD finger protein 1 |
increases expression |
ISO |
geraniol results in increased expression of PHF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
|
|
G |
Phf21a |
PHD finger protein 21A |
increases expression |
ISO |
geraniol results in increased expression of PHF21A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865
|
|
G |
Phtf1 |
putative homeodomain transcription factor 1 |
increases expression |
ISO |
geraniol results in increased expression of PHTF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
|
|
G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
|
|
G |
Pkmyt1 |
protein kinase, membrane associated tyrosine/threonine 1 |
decreases expression |
ISO |
geraniol results in decreased expression of PKMYT1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
|
|
G |
Plagl1 |
PLAG1 like zinc finger 1 |
increases expression |
ISO |
geraniol results in increased expression of PLAGL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
|
|
G |
Plk1 |
polo-like kinase 1 |
decreases expression |
ISO |
geraniol results in decreased expression of PLK1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
|
|
G |
Pola1 |
DNA polymerase alpha 1, catalytic subunit |
decreases expression |
ISO |
geraniol results in decreased expression of POLA1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
|
|
G |
Pole |
DNA polymerase epsilon, catalytic subunit |
decreases expression |
ISO |
geraniol results in decreased expression of POLE mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
|
|
G |
Polr1g |
RNA polymerase I subunit G |
decreases expression |
ISO |
geraniol results in decreased expression of POLR1G mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766
|
|
G |
Por |
cytochrome p450 oxidoreductase |
multiple interactions |
EXP |
geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased activity of POR protein] |
CTD |
PMID:23499697 |
|
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions increases activity |
EXP ISO |
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA] geraniol results in increased activity of PPARA protein |
CTD |
PMID:21597168 PMID:26695085 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression increases activity multiple interactions |
ISO EXP |
geraniol results in decreased expression of PPARG mRNA geraniol results in increased activity of PPARG protein geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein] geraniol inhibits the reaction [Fructose results in decreased activity of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein] |
CTD |
PMID:21597168 PMID:25679220 PMID:26165751 PMID:27683099 PMID:30550845 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
|
|
G |
Prc1 |
protein regulator of cytokinesis 1 |
decreases expression |
ISO |
geraniol results in decreased expression of PRC1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
|
|
G |
Prdm4 |
PR/SET domain 4 |
increases expression |
ISO |
geraniol results in increased expression of PRDM4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:17,953,832...17,980,489
Ensembl chr 7:17,954,019...17,980,489
|
|
G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 mRNA]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 protein] |
CTD |
PMID:35608392 |
|
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
|
|
G |
Prdx3 |
peroxiredoxin 3 |
decreases expression |
ISO |
geraniol results in decreased expression of PRDX3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
|
|
G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Rotenone results in increased expression of PRKAA1 protein] |
CTD |
PMID:30141137 |
|
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
|
|
G |
Pten |
phosphatase and tensin homolog |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein] |
CTD |
PMID:28428697 |
|
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO EXP |
geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of PTGS2 protein] |
CTD |
PMID:20506077 PMID:21597168 PMID:22760862 PMID:23399806 PMID:26190278 PMID:26364502 PMID:26973525 PMID:28397014 PMID:29050341 More...
|
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
|
|
G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
decreases expression |
ISO |
geraniol results in decreased expression of PTTG1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
|
|
G |
Pwp1 |
PWP1 homolog, endonuclein |
decreases expression |
ISO |
geraniol results in decreased expression of PWP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731
|
|
G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
ISO |
geraniol results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
|
|
G |
Rad51 |
RAD51 recombinase |
decreases expression |
ISO |
geraniol results in decreased expression of RAD51 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
|
|
G |
Rad54b |
RAD54 homolog B |
decreases expression |
ISO |
geraniol results in decreased expression of RAD54B mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616
|
|
G |
Rad54l |
RAD54 like |
decreases expression |
ISO |
geraniol results in decreased expression of RAD54L mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
|
|
G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
ISO |
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein] |
CTD |
PMID:22760862 |
|
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
|
|
G |
Rcan1 |
regulator of calcineurin 1 |
increases expression |
ISO |
geraniol results in increased expression of RCAN1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
|
|
G |
Rcor3 |
REST corepressor 3 |
increases expression |
ISO |
geraniol results in increased expression of RCOR3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:103,624,966...103,665,565
Ensembl chr13:103,624,971...103,665,565
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO EXP |
geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein modified form]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein] geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of RELA protein]; geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of and affects the localization of RELA protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of RELA protein] |
CTD |
PMID:23399806 PMID:26190278 PMID:26364502 PMID:28397014 PMID:29050341 PMID:30550845 PMID:34343525 More...
|
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
|
|
G |
Rfx5 |
regulatory factor X5 |
increases expression |
ISO |
geraniol results in increased expression of RFX5 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:182,521,191...182,528,720
Ensembl chr 2:182,521,202...182,528,717
|
|
G |
Rnf19a |
ring finger protein 19A, RBR E3 ubiquitin protein ligase |
increases expression |
ISO |
geraniol results in increased expression of RNF19A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
|
|
G |
Ruvbl1 |
RuvB-like AAA ATPase 1 |
decreases expression |
ISO |
geraniol results in decreased expression of RUVBL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
|
|
G |
Ruvbl2 |
RuvB-like AAA ATPase 2 |
decreases expression |
ISO |
geraniol results in decreased expression of RUVBL2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
|
|
G |
Satb1 |
SATB homeobox 1 |
increases expression |
ISO |
geraniol results in increased expression of SATB1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
|
|
G |
Serpinb3 |
serpin family B member 3 |
increases expression |
ISO |
geraniol results in increased expression of SERPINB3 mRNA |
CTD |
PMID:30806763 |
|
NCBI chr13:23,274,120...23,280,660
Ensembl chr13:23,274,484...23,313,682
|
|
G |
Sim2 |
SIM bHLH transcription factor 2 |
increases expression |
ISO |
geraniol results in increased expression of SIM2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663
|
|
G |
Sirt1 |
sirtuin 1 |
increases expression |
ISO |
geraniol results in increased expression of SIRT1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
|
|
G |
Skp2 |
S-phase kinase associated protein 2 |
decreases expression |
ISO |
geraniol results in decreased expression of SKP2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
|
|
G |
Slc18a2 |
solute carrier family 18 member A2 |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC18A2 protein] |
CTD |
PMID:23943375 |
|
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
|
|
G |
Slc2a4rg |
SLC2A4 regulator |
decreases expression |
ISO |
geraniol results in decreased expression of SLC2A4RG mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:168,493,975...168,497,616
|
|
G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] |
CTD |
PMID:23943375 |
|
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
|
|
G |
Smad3 |
SMAD family member 3 |
decreases expression |
ISO |
geraniol results in decreased expression of SMAD3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
|
|
G |
Smad6 |
SMAD family member 6 |
decreases expression |
ISO |
geraniol results in decreased expression of SMAD6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
|
|
G |
Smad7 |
SMAD family member 7 |
increases expression |
ISO |
geraniol results in increased expression of SMAD7 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
|
|
G |
Smarca2 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
decreases expression |
ISO |
geraniol results in decreased expression of SMARCA2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
|
|
G |
Smarcal1 |
Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
increases expression |
ISO |
geraniol results in increased expression of SMARCAL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
|
|
G |
Smc4 |
structural maintenance of chromosomes 4 |
decreases expression |
ISO |
geraniol results in decreased expression of SMC4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
|
|
G |
Snca |
synuclein alpha |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA mRNA]; geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein] geraniol inhibits the reaction [Rotenone results in increased expression of SNCA protein]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Dopamine]; geraniol inhibits the reaction [SNCA protein results in decreased abundance of Glutathione]; geraniol inhibits the reaction [SNCA protein results in increased abundance of Thiobarbituric Acid Reactive Substances] |
CTD |
PMID:24103762 PMID:27026137 PMID:30141137 |
|
NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
|
|
G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
EXP ISO |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD1 mRNA] geraniol inhibits the reaction [Rotenone results in decreased activity of SOD1 protein] |
CTD |
PMID:22509279 PMID:30141137 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
|
|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP ISO |
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of SOD2 protein] geraniol inhibits the reaction [Rotenone results in decreased activity of SOD2 protein] |
CTD |
PMID:22509279 PMID:30141137 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
|
|
G |
Sox9 |
SRY-box transcription factor 9 |
decreases expression |
ISO |
geraniol results in decreased expression of SOX9 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
|
|
G |
Sp100 |
SP100 nuclear antigen |
increases expression |
ISO |
geraniol results in increased expression of SP100 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
|
|
G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
geraniol results in increased expression of SQSTM1 mRNA geraniol inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein] |
CTD |
PMID:27683099 PMID:30141137 |
|
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
|
|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
EXP |
geraniol promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SREBF1 mRNA] |
CTD |
PMID:26695085 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
|
|
G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
increases expression |
ISO |
geraniol results in increased expression of SREBF2 mRNA |
CTD |
PMID:23668785 |
|
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
increases expression |
ISO |
geraniol results in increased expression of STAT1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
|
|
G |
Stat2 |
signal transducer and activator of transcription 2 |
increases expression |
ISO |
geraniol results in increased expression of STAT2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
|
|
G |
Stat6 |
signal transducer and activator of transcription 6 |
increases expression |
ISO |
geraniol results in increased expression of STAT6 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
|
|
G |
Stmn1 |
stathmin 1 |
decreases expression |
ISO |
geraniol results in decreased expression of STMN1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
|
|
G |
Sub1 |
SUB1 regulator of transcription |
decreases expression |
ISO |
geraniol results in decreased expression of SUB1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436 Ensembl chr 2:61,005,666...61,020,436
|
|
G |
Supt16h |
SPT16 homolog, facilitates chromatin remodeling subunit |
decreases expression |
ISO |
geraniol results in decreased expression of SUPT16H mRNA |
CTD |
PMID:27683099 |
|
NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
|
|
G |
Supt5h |
SPT5 homolog, DSIF elongation factor subunit |
increases expression |
ISO |
geraniol results in increased expression of SUPT5H mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:83,586,713...83,616,971
Ensembl chr 1:83,586,718...83,616,892
|
|
G |
Tardbp |
TAR DNA binding protein |
decreases expression |
ISO |
geraniol results in decreased expression of TARDBP mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
|
|
G |
Tceal1 |
transcription elongation factor A like 1 |
increases expression |
ISO |
geraniol results in increased expression of TCEAL1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:100,058,485...100,060,439
Ensembl chr X:100,058,132...100,060,551
|
|
G |
Tcf12 |
transcription factor 12 |
increases expression |
ISO |
geraniol results in increased expression of TCF12 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201
|
|
G |
Tcf25 |
transcription factor 25 |
increases expression |
ISO |
geraniol results in increased expression of TCF25 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723
|
|
G |
Tcf4 |
transcription factor 4 |
decreases expression |
ISO |
geraniol results in decreased expression of TCF4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
|
|
G |
Tcf7l2 |
transcription factor 7 like 2 |
decreases expression |
ISO |
geraniol results in decreased expression of TCF7L2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
|
|
G |
Terf1 |
telomeric repeat binding factor 1 |
decreases expression |
ISO |
geraniol results in decreased expression of TERF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
|
|
G |
Tfap2a |
transcription factor AP-2 alpha |
increases expression |
ISO |
geraniol results in increased expression of TFAP2A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
|
|
G |
Tfcp2 |
transcription factor CP2 |
decreases expression |
ISO |
geraniol results in decreased expression of TFCP2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939
|
|
G |
Tfdp1 |
transcription factor Dp-1 |
decreases expression |
ISO |
geraniol results in decreased expression of TFDP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
|
|
G |
Tgif1 |
TGFB-induced factor homeobox 1 |
increases expression |
ISO |
geraniol results in increased expression of TGIF1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
|
|
G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
geraniol inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] |
CTD |
PMID:23943375 |
|
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
|
|
G |
Timeless |
timeless circadian regulator |
decreases expression |
ISO |
geraniol results in decreased expression of TIMELESS mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
|
|
G |
Tk1 |
thymidine kinase 1 |
decreases expression multiple interactions |
ISO |
geraniol results in decreased expression of TK1 mRNA Fluorouracil promotes the reaction [geraniol results in decreased expression of TK1 mRNA] |
CTD |
PMID:15374632 |
|
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
|
|
G |
Tle1 |
TLE family member 1, transcriptional corepressor |
increases expression |
ISO |
geraniol results in increased expression of TLE1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
|
|
G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 protein] |
CTD |
PMID:29050341 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA] 2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]]; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; geraniol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]] geraniol results in increased expression of TNF mRNA geraniol inhibits the reaction [4-Nitroquinoline-1-oxide results in increased expression of TNF protein]; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; geraniol inhibits the reaction [Fructose results in increased secretion of TNF protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of TNF protein] |
CTD |
PMID:21430599 PMID:23399806 PMID:25679220 PMID:26190278 PMID:26695085 PMID:26973525 PMID:28358702 PMID:28397014 PMID:29050341 PMID:30254419 PMID:30550845 PMID:34343525 PMID:35608392 More...
|
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Tp53 |
tumor protein p53 |
multiple interactions increases expression |
EXP ISO |
geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein] geraniol results in increased expression of TP53 mRNA |
CTD |
PMID:21907755 PMID:27683099 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
|
|
G |
Tpx2 |
TPX2, microtubule nucleation factor |
decreases expression |
ISO |
geraniol results in decreased expression of TPX2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
|
|
G |
Traip |
TRAF-interacting protein |
decreases expression |
ISO |
geraniol results in decreased expression of TRAIP mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
|
|
G |
Trak1 |
trafficking kinesin protein 1 |
increases expression |
ISO |
geraniol results in increased expression of TRAK1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367
|
|
G |
Trim29 |
tripartite motif-containing 29 |
increases expression |
ISO |
geraniol results in increased expression of TRIM29 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992
|
|
G |
Trps1 |
transcriptional repressor GATA binding 1 |
increases expression |
ISO |
geraniol results in increased expression of TRPS1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
|
|
G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
geraniol binds to and results in increased activity of TRPV1 protein |
CTD |
PMID:20686244 |
|
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
|
|
G |
Tsc22d3 |
TSC22 domain family, member 3 |
increases expression |
ISO |
geraniol results in increased expression of TSC22D3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861
|
|
G |
Ttk |
Ttk protein kinase |
decreases expression |
ISO |
geraniol results in decreased expression of TTK mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
|
|
G |
Tulp3 |
TUB like protein 3 |
increases expression |
ISO |
geraniol results in increased expression of TULP3 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
|
|
G |
Tulp4 |
TUB like protein 4 |
increases expression |
ISO |
geraniol results in increased expression of TULP4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688
|
|
G |
Tyms |
thymidylate synthetase |
multiple interactions decreases expression |
ISO |
Fluorouracil promotes the reaction [geraniol results in decreased expression of TYMS mRNA] |
CTD |
PMID:15374632 |
|
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
|
|
G |
Ube2c |
ubiquitin-conjugating enzyme E2C |
decreases expression |
ISO |
geraniol results in decreased expression of UBE2C mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
|
|
G |
Ube2n |
ubiquitin-conjugating enzyme E2N |
decreases expression |
ISO |
geraniol results in decreased expression of UBE2N mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
|
|
G |
Ubp1 |
upstream binding protein 1 |
decreases expression |
ISO |
geraniol results in decreased expression of UBP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625
|
|
G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
EXP |
geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of UCP2 protein] |
CTD |
PMID:26695085 |
|
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
geraniol inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 protein] geraniol inhibits the reaction [Dietary Fats results in increased expression of VCAM1 protein] |
CTD |
PMID:27107694 |
|
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
|
|
G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
geraniol inhibits the reaction [2-Acetylaminofluorene results in increased expression of VEGFA protein] |
CTD |
PMID:26364502 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
|
|
G |
Vldlr |
very low density lipoprotein receptor |
increases expression |
ISO |
geraniol results in increased expression of VLDLR mRNA |
CTD |
PMID:26141755 |
|
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
|
|
G |
Xbp1 |
X-box binding protein 1 |
increases expression |
ISO |
geraniol results in increased expression of XBP1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
|
|
G |
Zbtb1 |
zinc finger and BTB domain containing 1 |
increases expression |
ISO |
geraniol results in increased expression of ZBTB1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
|
|
G |
Zbtb10 |
zinc finger and BTB domain containing 10 |
increases expression |
ISO |
geraniol results in increased expression of ZBTB10 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
|
|
G |
Zbtb11 |
zinc finger and BTB domain containing 11 |
decreases expression |
ISO |
geraniol results in decreased expression of ZBTB11 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:44,598,694...44,652,559
Ensembl chr11:44,616,289...44,651,050
|
|
G |
Zbtb20 |
zinc finger and BTB domain containing 20 |
increases expression |
ISO |
geraniol results in increased expression of ZBTB20 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr11:57,052,129...57,791,214
Ensembl chr11:57,072,880...57,510,210
|
|
G |
Zfp110 |
zinc finger protein 110 |
increases expression |
ISO |
geraniol results in increased expression of ZNF274 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
|
|
G |
Zfp189 |
zinc finger protein 189 |
increases expression |
ISO |
geraniol results in increased expression of ZNF189 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:63,872,596...63,884,348
Ensembl chr 5:63,872,738...63,884,121
|
|
G |
Zfp207 |
zinc finger protein 207 |
decreases expression |
ISO |
geraniol results in decreased expression of ZNF207 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
|
|
G |
Zfp248 |
zinc finger protein 248 |
decreases expression |
ISO |
geraniol results in decreased expression of ZNF248 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:151,605,433...151,630,249
Ensembl chr 4:151,606,495...151,629,850
|
|
G |
Zfp263 |
zinc finger protein 263 |
increases expression |
ISO |
geraniol results in increased expression of ZNF263 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:11,764,424...11,774,324
Ensembl chr10:11,764,427...11,771,235
|
|
G |
Zfp281 |
zinc finger protein 281 |
increases expression |
ISO |
geraniol results in increased expression of ZNF281 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr13:48,096,103...48,104,265
Ensembl chr13:48,037,286...48,104,888
|
|
G |
Zfp329 |
zinc finger protein 329 |
increases expression |
ISO |
geraniol results in increased expression of ZNF329 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:73,403,067...73,498,349
Ensembl chr 1:73,402,972...73,422,037
|
|
G |
Zfp334 |
zinc finger protein 334 |
increases expression |
ISO |
geraniol results in increased expression of ZNF334 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 3:154,112,537...154,125,087
Ensembl chr 3:154,113,561...154,125,057
|
|
G |
Zfp354a |
zinc finger protein 354A |
increases expression |
ISO |
geraniol results in increased expression of ZNF354A mRNA |
CTD |
PMID:27683099 |
|
NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068
|
|
G |
Zfp394 |
zinc finger protein 394 |
increases expression |
ISO |
geraniol results in increased expression of ZNF394 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246
|
|
G |
Zfp410 |
zinc finger protein 410 |
increases expression |
ISO |
geraniol results in increased expression of ZNF410 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 6:103,963,265...103,990,252
Ensembl chr 6:103,964,060...103,990,225
|
|
G |
Zfp455l1 |
zinc finger protein 455 like 1 |
increases expression |
ISO |
geraniol results in increased expression of KRBOX4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:34,866,934...34,944,939
Ensembl chr 1:34,927,303...34,944,121
|
|
G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
geraniol results in increased expression of ZNF467 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
|
|
G |
Zfp606 |
zinc finger protein 606 |
increases expression |
ISO |
geraniol results in increased expression of ZNF606 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072
|
|
G |
Zfp612 |
zinc finger protein 612 |
increases expression |
ISO |
geraniol results in increased expression of ZNF23 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr19:38,053,953...38,071,196
Ensembl chr19:38,053,967...38,067,455
|
|
G |
Zfp68 |
zinc finger protein 68 |
increases expression |
ISO |
geraniol results in increased expression of ZNF84 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr12:16,026,058...16,040,995
Ensembl chr12:16,026,079...16,040,995
|
|
G |
Zfp75d |
zinc finger protein 75D |
increases expression |
ISO |
geraniol results in increased expression of ZNF75D mRNA |
CTD |
PMID:27683099 |
|
NCBI chr X:134,035,116...134,053,765
Ensembl chr X:134,036,143...134,051,519
|
|
G |
Zfp768 |
zinc finger protein 768 |
increases expression |
ISO |
geraniol results in increased expression of ZNF768 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 1:181,966,314...181,968,950
Ensembl chr 1:181,966,316...181,969,147
|
|
G |
Zhx2 |
zinc fingers and homeoboxes 2 |
increases expression |
ISO |
geraniol results in increased expression of ZHX2 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 7:89,226,358...89,374,266
Ensembl chr 7:89,226,463...89,374,378
|
|
G |
Zmiz1 |
zinc finger, MIZ-type containing 1 |
increases expression |
ISO |
geraniol results in increased expression of ZMIZ1 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
|
|
G |
Zmym4 |
zinc finger MYM-type containing 4 |
increases expression |
ISO |
geraniol results in increased expression of ZMYM4 mRNA |
CTD |
PMID:27683099 |
|
NCBI chr 5:139,146,782...139,264,387
Ensembl chr 5:139,146,665...139,264,421
|
|
G |
Zmynd11 |
zinc finger, MYND-type containing 11 |
increases expression |
ISO |
geraniol results in increased expression of ZMYND11 mRNA |
CTD |
|