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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:guaiacols
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Accession:CHEBI:134251 term browser browse the term
Definition:Any phenol carrying an additional methoxy substituent at the ortho-position.
Synonyms:related_synonym: 1-hydroxy-2-methoxybenzenes;   2-methoxyphenol;   2-methoxyphenol derivative;   2-methoxyphenol derivatives;   2-methoxyphenols;   a guaiacol;   catechol monomethyl ether;   catechol monomethyl ethers;   o-methoxyphenol;   o-methoxyphenols;   ortho-methoxyphenol;   ortho-methoxyphenols
 alt_id: CHEBI:13645
 xref: metacyc.compound:Guaiacols
 chemrof_formula: C7H4O2R4
 chemrof_smiles: [1*]c1c([2*])c([3*])c([4*])c(O)c1OC


show annotations for term's descendants           Sort by:
(+)-isolariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A decreases expression ISO isolariciresinol results in decreased expression of HNF1A mRNA CTD PMID:35755389 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO isolariciresinol results in decreased expression of LDLR protein CTD PMID:35755389 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO isolariciresinol results in decreased expression of PCSK9 mRNA; isolariciresinol results in decreased expression of PCSK9 protein CTD PMID:35755389 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isolariciresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO isolariciresinol results in decreased expression of SREBF1 mRNA CTD PMID:35755389 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 decreases expression ISO isolariciresinol results in decreased expression of SREBF2 mRNA CTD PMID:35755389 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
(+)-pinoresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression 		ISO [loliolide co-treated with pinoresinol] results in decreased expression of ACACA protein
pinoresinol results in decreased expression of ACACA protein 		CTD PMID:31610126 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression 		ISO [loliolide co-treated with pinoresinol] results in decreased expression of FASN protein
pinoresinol results in decreased expression of FASN protein 		CTD PMID:31610126 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H2 protein CTD PMID:31610126 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H3 protein CTD PMID:31610126 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pinoresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions 		ISO pinoresinol results in decreased expression of SREBF1 protein
[loliolide co-treated with pinoresinol] results in decreased expression of SREBF1 protein 		CTD PMID:31610126 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO pinoresinol results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
coniferyl aldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO coniferaldehyde results in increased expression of ABCC2 mRNA CTD PMID:26275128 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO coniferaldehyde results in increased expression of ABCC3 mRNA CTD PMID:26275128 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions
increases expression 		ISO NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of AKR1C1 protein]
coniferaldehyde results in increased expression of AKR1C1 mRNA; coniferaldehyde results in increased expression of AKR1C1 protein 		CTD PMID:26275128 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO coniferaldehyde results in increased expression of AKR1C2 mRNA; coniferaldehyde results in increased expression of AKR1C2 protein CTD PMID:26275128 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO coniferaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:26275128 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO coniferaldehyde results in increased expression of GCLC mRNA CTD PMID:26275128 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO coniferaldehyde results in increased expression of GCLM mRNA CTD PMID:26275128 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO coniferaldehyde results in increased expression of GSR mRNA
coniferaldehyde results in increased expression of GSR protein 		CTD PMID:26275128 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; MAPK14 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; PKN3 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; Ro 31-8220 inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]
coniferaldehyde results in increased expression of HMOX1 mRNA; coniferaldehyde results in increased expression of HMOX1 protein 		CTD PMID:26275128 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Ifng interferon gamma multiple interactions ISO coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of STAT1 protein] CTD PMID:27378624 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein]
coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] 		CTD PMID:27378624 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO MAPK14 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; MAPK14 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] CTD PMID:26275128 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions ISO MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] CTD PMID:26275128 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions 		ISO coniferaldehyde results in increased expression of MUC5AC mRNA
2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [coniferaldehyde results in increased expression of MUC5AC mRNA]; A 967079 inhibits the reaction [coniferaldehyde results in increased expression of MUC5AC mRNA]; coniferaldehyde results in increased expression of and results in increased secretion of MUC5AC protein; TWS 119 inhibits the reaction [coniferaldehyde results in increased expression of MUC5AC mRNA] 		CTD PMID:31944254 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression 		ISO coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein; MAPK14 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; MAPKAPK2 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of AKR1C1 protein]; NFE2L2 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]; PKN3 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]
coniferaldehyde results in increased expression of NFE2L2 protein 		CTD PMID:26275128 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein]
coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] 		CTD PMID:27378624 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO coniferaldehyde results in increased expression of NQO1 protein CTD PMID:26275128 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Pkn3 protein kinase N3 multiple interactions ISO PKN3 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]; PKN3 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] CTD PMID:26275128 NCBI chr 3:33,747,610...33,761,405
Ensembl chr 3:33,747,867...33,761,405 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of STAT1 protein]
coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of STAT1 protein modified form]; coniferaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of STAT1 protein] 		CTD PMID:27378624 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of JAK2 protein]; coniferaldehyde inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased phosphorylation of STAT1 protein] CTD PMID:27378624 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO coniferaldehyde results in increased activity of TRPA1 protein CTD PMID:23541125 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO coniferaldehyde results in increased expression of TXNRD1 mRNA CTD PMID:26275128 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
gingerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO gingerol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:18385293 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO gingerol inhibits the reaction [TNF protein results in decreased expression of ADIPOQ mRNA]; gingerol inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of ADIPOQ protein] CTD PMID:18577375 PMID:21851089 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO gingerol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein] CTD PMID:27451028 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO gingerol results in increased expression of APAF1 mRNA; gingerol results in increased expression of APAF1 protein CTD PMID:19481070 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein]; gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BCL2 protein]; gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CASP3 protein]; gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of RELA protein]; gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein] CTD PMID:37121058 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO gingerol inhibits the reaction [TNF protein results in increased phosphorylation of ATF2 protein] CTD PMID:18577375 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		ISO Acetylcysteine inhibits the reaction [gingerol results in increased expression of BAX protein]; gingerol inhibits the reaction [Testosterone results in decreased expression of BAX protein]
gingerol inhibits the reaction [hypoxia-reoxygenation increases expression of Bax protein in neural crest-derived cells]
gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BAX protein]; gingerol inhibits the reaction [Testosterone results in decreased expression of BAX protein]; gingerol inhibits the reaction [TNF protein results in increased expression of BAX protein]
gingerol results in increased expression of BAX mRNA; gingerol results in increased expression of BAX protein 		CTD
RGD		 PMID:18030663 PMID:19481070 PMID:25034532 PMID:28249781 PMID:37121058 More... RGD:155882488 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO gingerol results in decreased expression of BCL2 mRNA; gingerol results in decreased expression of BCL2 protein
gingerol inhibits the reaction [hypoxia-reoxygenation decreases expression of Bcl2 protein in neural crest-derived cells]
gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of BCL2 protein]; gingerol inhibits the reaction [Testosterone results in increased expression of BCL2 protein]; gingerol inhibits the reaction [TNF protein results in decreased expression of BCL2 protein]
[gingerol co-treated with Hydrogen Peroxide] results in increased expression of BCL2 protein; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BCL2 protein]; gingerol inhibits the reaction [Testosterone results in increased expression of BCL2 protein] 		CTD
RGD		 PMID:18030663 PMID:19481070 PMID:25034532 PMID:27451028 PMID:28249781 More... RGD:155882488 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO gingerol inhibits the reaction [hypoxia-reoxygenation decreases expression of Bdnf protein in neural crest-derived cells] RGD PMID:34962339 RGD:155882488 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO [gingerol co-treated with Hydrogen Peroxide] results in increased expression of BECN1 protein CTD PMID:27451028 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression 		ISO Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein] CTD PMID:25034532 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression 		ISO Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BIRC5 protein]; gingerol inhibits the reaction [Testosterone results in increased expression of BIRC5 protein] CTD PMID:18030663 PMID:25034532 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
multiple interactions
affects activity 		ISO
EXP 		gingerol results in increased expression of CASP3 mRNA; gingerol results in increased expression of CASP3 protein
gingerol results in increased cleavage of CASP3 protein
gingerol inhibits the reaction [Chlorpyrifos results in increased activity of CASP3 protein]
gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CASP3 protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased activity of CASP3 protein]; gingerol inhibits the reaction [Testosterone results in decreased expression of CASP3 protein]; gingerol inhibits the reaction [TNF protein results in increased expression of CASP3 protein]
gingerol affects the activity of CASP3 protein
[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; gingerol inhibits the reaction [Testosterone results in decreased expression of CASP3 protein] 		CTD PMID:17454143 PMID:18030663 PMID:19481070 PMID:25034532 PMID:28249781 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
affects activity 		ISO [TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]
gingerol results in increased cleavage of CASP8 protein
gingerol affects the activity of CASP8 protein 		CTD PMID:17454143 PMID:25034532 PMID:28249781 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases expression
increases cleavage
multiple interactions
affects activity 		ISO gingerol results in increased expression of CASP9 mRNA; gingerol results in increased expression of CASP9 protein
gingerol results in increased cleavage of CASP9 protein
gingerol inhibits the reaction [Testosterone results in decreased expression of CASP9 protein]
gingerol affects the activity of CASP9 protein 		CTD PMID:17454143 PMID:18030663 PMID:19481070 PMID:28249781 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions ISO
EXP 		gingerol inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; gingerol inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; gingerol inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
gingerol inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein] 		CTD PMID:22285432 PMID:28373059 PMID:28421826 PMID:31004597 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO gingerol results in decreased expression of CCNB1 mRNA; gingerol results in decreased expression of CCNB1 protein CTD PMID:28249781 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
decreases expression 		ISO [gingerol co-treated with Cycloheximide] results in increased degradation of CCND1 protein
gingerol results in increased expression of CCND1 mRNA; gingerol results in increased expression of CCND1 protein
gingerol results in decreased expression of CCND1 mRNA; gingerol results in decreased expression of CCND1 protein 		CTD PMID:18058799 PMID:26498061 PMID:28249781 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO gingerol results in decreased expression of CCNE1 mRNA; gingerol results in decreased expression of CCNE1 protein CTD PMID:28249781 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO gingerol results in decreased expression of CDK1 mRNA CTD PMID:28249781 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO gingerol results in decreased expression of CDK4 protein CTD PMID:18058799 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO gingerol results in decreased expression of CDKN1A mRNA CTD PMID:28249781 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO gingerol results in decreased expression of CDKN1B mRNA CTD PMID:28249781 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions 		ISO gingerol results in decreased expression of CEBPA mRNA; gingerol results in decreased expression of CEBPA protein
GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA mRNA]; GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA protein] 		CTD PMID:26498061 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
decreases expression 		ISO Acetylcysteine inhibits the reaction [gingerol results in decreased expression of CFLAR protein] CTD PMID:25034532 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO gingerol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CHEK2 protein] CTD PMID:28988496 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667 		JBrowse link
G Ctnnb1 catenin beta 1 affects localization
increases expression
multiple interactions 		ISO gingerol affects the localization of CTNNB1 protein
gingerol results in increased expression of CTNNB1 mRNA
gingerol results in increased expression of and affects the localization of CTNNB1 protein
gingerol promotes the reaction [IL1B protein results in increased expression of CTNNB1 protein] 		CTD PMID:18058799 PMID:26498061 PMID:27645308 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases response to substance ISO CYP2C19 mRNA results in increased susceptibility to gingerol CTD PMID:29555536 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO gingerol inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam] CTD PMID:18385293 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO gingerol results in increased expression of DUSP10 mRNA CTD PMID:17151092 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 increases expression ISO gingerol results in increased expression of DVL2 mRNA CTD PMID:26498061 NCBI chr10:55,222,245...55,231,506
Ensembl chr10:55,222,056...55,231,506 		JBrowse link
G Fas Fas cell surface death receptor affects activity ISO gingerol affects the activity of FAS protein CTD PMID:17454143 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO gingerol results in decreased expression of FASN mRNA; gingerol results in decreased expression of FASN protein CTD PMID:26498061 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO gingerol inhibits the reaction [Glucose results in increased secretion of FN1 protein] CTD PMID:21829520 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO gingerol inhibits the reaction [Dextran Sulfate results in decreased expression of FSHB protein] CTD PMID:28421826 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions 		ISO gingerol results in increased expression of GDF15 mRNA; gingerol results in increased expression of GDF15 protein
GSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein]; PRKCE protein affects the reaction [gingerol results in increased expression of GDF15 protein]; Ro 31-8220 inhibits the reaction [gingerol results in increased expression of GDF15 protein] 		CTD PMID:18058799 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases response to substance
increases phosphorylation
increases expression 		ISO gingerol inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; gingerol inhibits the reaction [IL1B protein results in increased phosphorylation of GSK3B protein]; GSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein]
GSK3B protein results in increased susceptibility to gingerol
GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA mRNA]; GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA protein]; GSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG mRNA]; GSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG protein]
gingerol results in increased phosphorylation of GSK3B protein
gingerol results in increased expression of GSK3B protein 		CTD PMID:18058799 PMID:26498061 PMID:27645308 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO gingerol inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA] CTD PMID:21382473 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases activity ISO gingerol results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:58,138,226...58,150,884 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO gingerol inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; gingerol inhibits the reaction [IL1B protein results in increased phosphorylation of GSK3B protein]; gingerol promotes the reaction [IL1B protein results in increased expression of CTNNB1 protein]
gingerol inhibits the reaction [Benzo(a)pyrene results in increased expression of IL1B protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein] 		CTD PMID:27645308 PMID:28421826 PMID:31004597 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO gingerol inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA] CTD PMID:22285432 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO gingerol inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; gingerol inhibits the reaction [sodium arsenite results in decreased expression of INS1 protein]; gingerol inhibits the reaction [sodium arsenite results in decreased secretion of INS1 protein] CTD PMID:21851089 PMID:22285432 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO gingerol inhibits the reaction [sodium arsenite results in decreased expression of IRS1 mRNA]; gingerol inhibits the reaction [sodium arsenite results in decreased expression of IRS1 protein] CTD PMID:22285432 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO gingerol inhibits the reaction [sodium arsenite results in decreased expression of IRS2 mRNA]; gingerol inhibits the reaction [sodium arsenite results in decreased expression of IRS2 protein] CTD PMID:22285432 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO gingerol inhibits the reaction [TNF protein results in increased phosphorylation of JUN protein] CTD PMID:18577375 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Klkb1 kallikrein B1 multiple interactions
decreases expression 		ISO gingerol inhibits the reaction [Testosterone results in increased expression of KLKB1 protein]
gingerol results in decreased expression of KLKB1 protein 		CTD PMID:18030663 NCBI chr16:53,690,180...53,714,570
Ensembl chr16:53,691,220...53,716,339 		JBrowse link
G Lats1 large tumor suppressor kinase 1 increases expression ISO gingerol results in increased expression of LATS1 protein CTD PMID:32926756 NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:3,980,544...4,014,029 		JBrowse link
G Ldhc lactate dehydrogenase C multiple interactions ISO gingerol inhibits the reaction [Dextran Sulfate results in increased activity of LDHC protein] CTD PMID:28421826 NCBI chr 1:106,522,140...106,539,649
Ensembl chr 1:106,522,236...106,542,802 		JBrowse link
G Lep leptin multiple interactions ISO gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP mRNA]; gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP protein] CTD PMID:21851089 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO gingerol inhibits the reaction [Dextran Sulfate results in decreased expression of LHB protein] CTD PMID:28421826 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lrp6 LDL receptor related protein 6 increases expression ISO gingerol results in increased expression of LRP6 mRNA CTD PMID:26498061 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [gingerol co-treated with Hydrogen Peroxide] results in increased expression of MAP1LC3B protein modified form CTD PMID:27451028 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO gingerol inhibits the reaction [TNF protein results in increased phosphorylation of MAP2K4 protein] CTD PMID:18577375 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Mir210 microRNA 210 multiple interactions ISO gingerol inhibits the reaction [hypoxia-reoxygenation increases expression of Mir210 miRNA in neural crest-derived cells] RGD PMID:34962339 RGD:155882488 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
decreases activity 		ISO gingerol results in decreased expression of MMP2 mRNA; gingerol results in decreased expression of MMP2 protein
gingerol inhibits the reaction [YAP1 protein results in increased expression of MMP2 protein]
gingerol results in decreased activity of MMP2 protein 		CTD PMID:17683926 PMID:32926756 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
decreases activity 		ISO gingerol results in decreased expression of MMP9 mRNA
gingerol results in decreased activity of MMP9 protein 		CTD PMID:17683926 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP
ISO 		gingerol inhibits the reaction [Chlorpyrifos results in increased activity of MPO protein]
gingerol inhibits the reaction [Benzo(a)pyrene results in increased activity of MPO protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] 		CTD PMID:28373059 PMID:28421826 PMID:31004597 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases expression 		ISO gingerol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MTOR protein]
gingerol results in decreased expression of MTOR protein modified form 		CTD PMID:27451028 PMID:28249781 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO gingerol inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] CTD PMID:18683823 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO gingerol affects the phosphorylation of and affects the activity of NFKBIA protein CTD PMID:17454143 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO gingerol inhibits the reaction [Benzo(a)pyrene results in increased expression of NOS2 protein]; gingerol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; gingerol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] CTD PMID:18683823 PMID:31004597 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein] CTD PMID:25034532 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression 		ISO gingerol inhibits the reaction [sodium arsenite results in decreased expression of PPARG mRNA]; gingerol inhibits the reaction [sodium arsenite results in decreased expression of PPARG protein]; GSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG mRNA]; GSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG protein]
gingerol results in decreased expression of PPARG mRNA; gingerol results in decreased expression of PPARG protein 		CTD PMID:22285432 PMID:26498061 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO PRKCE protein affects the reaction [gingerol results in increased expression of GDF15 protein] CTD PMID:18058799 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Ptges prostaglandin E synthase decreases expression
increases expression 		ISO gingerol results in decreased expression of PTGES protein
gingerol results in increased expression of PTGES mRNA 		CTD PMID:27645308 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions 		ISO gingerol affects the expression of PTGS2 mRNA; gingerol affects the expression of PTGS2 protein
gingerol inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] 		CTD PMID:17454143 PMID:18683823 PMID:31004597 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO gingerol results in decreased phosphorylation of RB1 protein CTD PMID:18058799 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects expression
multiple interactions
affects localization 		ISO gingerol affects the expression of RELA protein
gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of RELA protein]; gingerol inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]]; gingerol inhibits the reaction [TNF protein results in increased expression of RELA protein]
gingerol affects the localization of RELA protein 		CTD PMID:17454143 PMID:18683823 PMID:37121058 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression ISO gingerol results in decreased expression of RPS6KB1 protein modified form CTD PMID:28249781 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO gingerol inhibits the reaction [sodium arsenite results in decreased expression of SLC2A4 mRNA]; gingerol inhibits the reaction [sodium arsenite results in decreased expression of SLC2A4 protein] CTD PMID:22285432 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO gingerol inhibits the reaction [Glucose results in increased expression of SNAI1 mRNA] CTD PMID:21829520 NCBI chr 3:176,667,476...176,671,965 JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression
multiple interactions 		ISO gingerol results in decreased expression of SNAI2 protein
gingerol inhibits the reaction [YAP1 protein results in increased expression of SNAI2 protein] 		CTD PMID:32926756 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO gingerol inhibits the reaction [Oxygen deficiency results in decreased activity of SOD1 protein]; gingerol inhibits the reaction [Oxygen deficiency results in decreased expression of SOD1 mRNA] CTD PMID:21382473 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO gingerol inhibits the reaction [Oxygen deficiency results in decreased activity of SOD2 protein]; gingerol inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 mRNA] CTD PMID:21382473 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		gingerol inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; gingerol inhibits the reaction [sodium arsenite results in increased expression of TNF mRNA]; gingerol inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; gingerol inhibits the reaction [TNF protein results in decreased expression of ADIPOQ mRNA]; gingerol inhibits the reaction [TNF protein results in decreased expression of and results in decreased secretion of ADIPOQ protein]; gingerol inhibits the reaction [TNF protein results in decreased expression of BCL2 protein]; gingerol inhibits the reaction [TNF protein results in increased expression of BAX protein]; gingerol inhibits the reaction [TNF protein results in increased expression of CASP3 protein]; gingerol inhibits the reaction [TNF protein results in increased expression of RELA protein]; gingerol inhibits the reaction [TNF protein results in increased expression of TRP53 protein]; gingerol inhibits the reaction [TNF protein results in increased phosphorylation of ATF2 protein]; gingerol inhibits the reaction [TNF protein results in increased phosphorylation of JUN protein]; gingerol inhibits the reaction [TNF protein results in increased phosphorylation of MAP2K4 protein]
gingerol inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein] 		CTD PMID:18577375 PMID:21851089 PMID:22285432 PMID:28373059 PMID:28421826 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases response to substance 		ISO [gingerol results in increased expression of TP53 protein] which results in increased susceptibility to TNFSF10 protein; [TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein; [TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein; [TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]; TP53 protein affects the reaction [gingerol results in increased susceptibility to TNFSF10 protein] CTD PMID:25034532 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions 		ISO gingerol results in increased expression of TP53 protein
gingerol inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein]; gingerol inhibits the reaction [Testosterone results in decreased expression of TRP53 protein]; gingerol inhibits the reaction [TNF protein results in increased expression of TRP53 protein]
[gingerol results in increased expression of TP53 protein] which results in increased susceptibility to TNFSF10 protein; [Testosterone co-treated with gingerol] results in increased expression of TP53 protein; gingerol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein]; TP53 protein affects the reaction [gingerol results in increased expression of TNFRSF10B protein]; TP53 protein affects the reaction [gingerol results in increased susceptibility to TNFSF10 protein] 		CTD PMID:18030663 PMID:25034532 PMID:28988496 PMID:37121058 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vim vimentin decreases expression
multiple interactions 		ISO gingerol results in decreased expression of VIM protein
gingerol inhibits the reaction [YAP1 protein results in increased expression of VIM protein] 		CTD PMID:32926756 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO gingerol results in decreased expression of XIAP protein CTD PMID:25034532 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator affects localization
multiple interactions 		ISO gingerol affects the localization of YAP1 protein
[gingerol co-treated with YAP1 protein] results in increased phosphorylation of YAP1 protein; gingerol inhibits the reaction [YAP1 protein results in increased expression of MMP2 protein]; gingerol inhibits the reaction [YAP1 protein results in increased expression of SNAI2 protein]; gingerol inhibits the reaction [YAP1 protein results in increased expression of VIM protein]; gingerol results in decreased expression of and results in increased phosphorylation of YAP1 protein 		CTD PMID:32926756 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437 		JBrowse link
guaiacol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Guaiacol binds to ALB protein CTD PMID:11334365 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Ca1 carbonic anhydrase 1 decreases activity ISO Guaiacol results in decreased activity of CA1 protein CTD PMID:19231207 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Guaiacol results in decreased activity of CA2 protein CTD PMID:19231207 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO COMT mutant form inhibits the reaction [catechol results in increased abundance of Guaiacol] CTD PMID:24141029 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Guaiacol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:17465205 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 increases sulfation ISO SULT1C1 protein results in increased sulfation of Guaiacol CTD PMID:9560327 NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295 		JBrowse link
homovanillic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp9 aquaporin 9 multiple interactions ISO AQP9 gene mutant form inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased abundance of Homovanillic Acid] CTD PMID:29566083 NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO
EXP 		[tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Homovanillic Acid CTD PMID:11793163 PMID:15190105 PMID:16012872 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Maob monoamine oxidase B multiple interactions EXP [Selegiline results in decreased activity of MAOB protein] which results in decreased abundance of Homovanillic Acid CTD PMID:16012872 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Homovanillic Acid] CTD PMID:11085313 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases abundance ISO NR3C1 protein results in increased abundance of Homovanillic Acid CTD PMID:11226678 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP [beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of Homovanillic Acid] CTD PMID:8884884 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] which results in increased abundance of Homovanillic Acid CTD PMID:10318960 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Sct secretin increases abundance ISO SCT protein results in increased abundance of Homovanillic Acid CTD PMID:16168596 NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:205,812,435...205,813,246 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP Homovanillic Acid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
G Tfam transcription factor A, mitochondrial decreases abundance ISO TFAM gene mutant form results in decreased abundance of Homovanillic Acid CTD PMID:28595911 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877 		JBrowse link
G Vdr vitamin D receptor multiple interactions
increases abundance 		ISO Calcitriol promotes the reaction [VDR protein results in increased abundance of Homovanillic Acid] CTD PMID:27450565 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
isorhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Hydrogen Peroxide]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO isorhapontigenin results in decreased expression of CCND1 protein CTD PMID:37619952 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in increased expression of CDH1 protein CTD PMID:37619952 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased localization of CTNNB1 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased phosphorylation of CTNNB1 protein CTD PMID:37619952 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT1 protein CTD PMID:37619952 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3A protein CTD PMID:37619952 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3B protein CTD PMID:37619952 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression EXP isorhapontigenin affects the expression of FOS protein CTD PMID:15607907 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in increased phosphorylation of GSK3B protein CTD PMID:37619952 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects activity EXP isorhapontigenin affects the activity of IKBKB protein CTD PMID:15607907 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression EXP isorhapontigenin affects the expression of JUN protein CTD PMID:15607907 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:15607907 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:15607907 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Meg3 maternally expressed 3 multiple interactions ISO isorhapontigenin inhibits the reaction [sodium bichromate results in decreased expression of MEG3] CTD PMID:37619952 NCBI chr 6:134,274,056...134,306,249 JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO isorhapontigenin results in decreased expression of MKI67 protein CTD PMID:37619952 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of and results in decreased localization of NEDD9 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of NEDD9 mRNA CTD PMID:37619952 NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,495,492...23,675,668 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP isorhapontigenin affects the degradation of and affects the phosphorylation of NFKBIA protein CTD PMID:15607907 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of SNAI2 protein CTD PMID:37619952 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349 		JBrowse link
isosilybin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression 		ISO isosilybin inhibits the reaction [T0901317 results in increased expression of ACACA mRNA]
isosilybin results in decreased expression of ACACA mRNA 		CTD PMID:36347319 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO isosilybin results in increased expression of ACOX1 mRNA CTD PMID:36347319 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA] CTD PMID:36347319 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] CTD PMID:36347319 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Fas Fas cell surface death receptor decreases expression
multiple interactions 		ISO isosilybin results in decreased expression of FAS mRNA
isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein] 		CTD PMID:36347319 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA]; isosilybin inhibits the reaction [T0901317 results in decreased expression of MTTP mRNA] CTD PMID:36347319 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression
multiple interactions 		ISO isosilybin results in decreased expression of PNPLA3 mRNA
isosilybin inhibits the reaction [T0901317 results in increased expression of PNPLA3 mRNA] 		CTD PMID:36347319 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:117,173,516...117,194,594 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] CTD PMID:36347319 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions 		ISO isosilybin results in decreased expression of SREBF1 mRNA
isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; isosilybin inhibits the reaction [T0901317 results in increased expression of SREBF1 mRNA]; isosilybin inhibits the reaction [T0901317 results in increased expression of SREBF1 protein] 		CTD PMID:36347319 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
ortho-vanillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 2-vanillin CTD PMID:15117964 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
rhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases activity ISO rhapontigenin analog results in increased activity of ESR1 protein CTD PMID:17935960 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 increases activity
multiple interactions 		ISO rhapontigenin analog results in increased activity of ESR2 protein
Fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein] 		CTD PMID:17692514 PMID:17935960 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Tf transferrin multiple interactions ISO rhapontigenin analog inhibits the reaction [Lipopolysaccharides results in increased activity of TF protein] CTD PMID:16507316 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400 		JBrowse link
vanillyl alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Or5d18 olfactory receptor family 5 subfamily D member 18 multiple interactions ISO vanillyl alcohol binds to and results in increased activity of OR5D18 protein CTD PMID:21142015 NCBI chr 3:93,972,754...93,973,695
Ensembl chr 3:93,972,754...93,973,695 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      molecular entity 20871
        polyatomic entity 20745
          heteroatomic molecular entity 20606
            hydroxides 19922
              organic hydroxy compound 19685
                phenols 19382
                  guaiacols 146
                    (+)-(7''S,8S,8'R,8''S)-4,4''-dihydroxy-3,3',3'',5'-tetramethoxy-4',8''-oxy-8,8'-sesquineolignan-7''-ol 0
                    (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5,5'-dimethoxy-2,7'-cyclolignan 0
                    (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5-methoxy-2,7'-cyclolignan 0
                    (+)-(7S,8R,7'E)-4-hydroxy-3,5'-dimethoxy-4',7-epoxy-8,3'-neolign-7'-ene-9,9'-diol-9'-ethyl ether 0
                    (+)-(7S,8S)-guaiacylglycerol-beta-vanillic acid ether 0
                    (+)-(8S,8'R)-3',4,4'-trihydroxy-5,5'-dimethoxylignan 0
                    (+)-(8S,8'R)-4,4'-dihydroxy-3-methoxylignan 0
                    (+)-(8S,8'R)-4-hydroxy-5-methoxy-1',2',3',4',5',6'-hexanor-2,7'-cyclolignan-7'-one 0
                    (+)-DCA-CC 0
                    (+)-DCA-CL 0
                    (+)-isolariciresinol 6
                    (-)-(7'S,7''S,8R,8'S,8''R)-4,4''-dihydroxy-3',3'',5-trimethoxy-4',8''-oxy-2,7'-cyclo-8,8'-sesquineolignan-7''-ol 0
                    (-)-(7R,8S,7''S,8''R)-3,3'',5,5'-tetramethoxy-4''-hydroxy-4',7-epoxy-8',9'-dinor-4,8''-oxy-8,3'-sesquineolignan-7'',9,9''-triol-7'-al 0
                    (-)-(8R,8'S)-3,3',4-trimethoxy-4'-hydroxylignan 0
                    (-)-DCA-CC 0
                    (-)-DCA-CL 0
                    (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                    (2R,3S)-dihydrodehydrodiconiferyl alcohol 0
                    (2S,3R)-dihydrodehydrodiconiferyl alcohol 0
                    (5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone 0
                    (7R)-7-hydroxylariciresinol 0
                    (7R)-7-hydroxytaxiresinol 0
                    (7S,8S)-methoxy-3',7-epoxy-8,4'-oxyneolignan-4,9,9'-triol 0
                    1,2-diguaiacylpropane-1,3-diol 0
                    1-(2-hydroxy-4-methoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)propane 0
                    1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-(4E)-4-hepten-3-one 0
                    1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3-heptanone 0
                    2,2'-dihydroxy-3,3'-dimethoxy-5,5'-dipropyldiphenylmethane 0
                    2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-7H-pyrano[2,3-g][1,4]benzodioxin-7-one 0
                    2-hydroxy-6-[2-(3,4-dihydroxyphenyl-5-methoxy)-2-oxoethyl]benzoic acid 0
                    2-methoxy-6-(all-trans-polyprenyl)phenol + 0
                    2-methoxyresorcinol sulfate 0
                    3,3''-dihydroxy-6'-O-desmethylterphenyllin 0
                    3-hydroxy-6'-O-desmethylterphenyllin 0
                    4'-O-methylnorbelladine 0
                    4,6-dinitroguaiacol 0
                    4-(1-hydroxypropyl)-2-methoxy-6-(2-methoxy-4-propylphenoxy)phenol 0
                    4-hydroxy-3-methoxybenzene-1-sulfonic acid 0
                    4-hydroxy-3-methoxycinnamoylagmatine + 0
                    4alpha-hydroxypinoresinol 0
                    4beta-[(beta-D-glucopyranosyl)hydroxy]-pinoresinol 0
                    5-O-desmethyldonepezil 0
                    5-hydroxyconiferyl alcohol + 0
                    6'',7''-dihydro-5',5'''-dicapsaicin 0
                    6'-O-desmethylterphenyllin 0
                    7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-4E-heptene-3-one 0
                    7-(4''-hydroxy-3''-methoxyphenyl)-5-methoxy-1-phenyl-3-heptanone 0
                    Cuscuta propenamide 2 0
                    N-octylhomovanillamide 0
                    N-trans-feruloyl-4'-O-methyldopamine 0
                    NK372135C 0
                    buddlenol E 0
                    coniferol 0
                    coniferyl aldehyde 22
                    coniferyl benzoate 0
                    coniferyl p-coumarate 0
                    dehydrodiconiferyl alcohol + 0
                    dichotomoside D 0
                    dihydroferulic acid 0
                    gingerenone B 0
                    gingerol 80
                    glycosmisic acid + 0
                    glycosmisic acid sulfate 0
                    guaiacol 6
                    guaiacylglycerol + 0
                    homoeriodictyol chalcone 0
                    homovanillic acid 11
                    isorhapontigenin 19
                    isosilybin 9
                    kadsurenin K 0
                    lamellarin alpha 20-hydrogen sulfate 0
                    matairesinoside 0
                    meso-dihydroguaiaretic acid 0
                    negundin B 0
                    ortho-vanillin 1
                    pinoresinol + 7
                    rhapontigenin 3
                    salicifoliol 0
                    tanegool 0
                    taxiresinol 0
                    threo-1-(4-hydroxy-3-methoxyphenyl)-2-\{4-[-(E)-3-hydroxy-1-propenyl]-2-methoxyphenoxy\}-1,3-propanediol 0
                    trans-methylferulate 0
                    triptohypol A 0
                    vanillyl alcohol 1
                    vanillyl beta-D-glucopyranoside 0
                    vladinol D 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                carbocyclic compound 18739
                                  benzenoid aromatic compound 17899
                                    benzenes 17656
                                      methoxybenzenes 2273
                                        monomethoxybenzene 1195
                                          guaiacols 146
                                            (+)-(7''S,8S,8'R,8''S)-4,4''-dihydroxy-3,3',3'',5'-tetramethoxy-4',8''-oxy-8,8'-sesquineolignan-7''-ol 0
                                            (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5,5'-dimethoxy-2,7'-cyclolignan 0
                                            (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5-methoxy-2,7'-cyclolignan 0
                                            (+)-(7S,8R,7'E)-4-hydroxy-3,5'-dimethoxy-4',7-epoxy-8,3'-neolign-7'-ene-9,9'-diol-9'-ethyl ether 0
                                            (+)-(7S,8S)-guaiacylglycerol-beta-vanillic acid ether 0
                                            (+)-(8S,8'R)-3',4,4'-trihydroxy-5,5'-dimethoxylignan 0
                                            (+)-(8S,8'R)-4,4'-dihydroxy-3-methoxylignan 0
                                            (+)-(8S,8'R)-4-hydroxy-5-methoxy-1',2',3',4',5',6'-hexanor-2,7'-cyclolignan-7'-one 0
                                            (+)-DCA-CC 0
                                            (+)-DCA-CL 0
                                            (+)-isolariciresinol 6
                                            (-)-(7'S,7''S,8R,8'S,8''R)-4,4''-dihydroxy-3',3'',5-trimethoxy-4',8''-oxy-2,7'-cyclo-8,8'-sesquineolignan-7''-ol 0
                                            (-)-(7R,8S,7''S,8''R)-3,3'',5,5'-tetramethoxy-4''-hydroxy-4',7-epoxy-8',9'-dinor-4,8''-oxy-8,3'-sesquineolignan-7'',9,9''-triol-7'-al 0
                                            (-)-(8R,8'S)-3,3',4-trimethoxy-4'-hydroxylignan 0
                                            (-)-DCA-CC 0
                                            (-)-DCA-CL 0
                                            (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                            (2R,3S)-dihydrodehydrodiconiferyl alcohol 0
                                            (2S,3R)-dihydrodehydrodiconiferyl alcohol 0
                                            (5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone 0
                                            (7R)-7-hydroxylariciresinol 0
                                            (7R)-7-hydroxytaxiresinol 0
                                            (7S,8S)-methoxy-3',7-epoxy-8,4'-oxyneolignan-4,9,9'-triol 0
                                            1,2-diguaiacylpropane-1,3-diol 0
                                            1-(2-hydroxy-4-methoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)propane 0
                                            1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-(4E)-4-hepten-3-one 0
                                            1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3-heptanone 0
                                            2,2'-dihydroxy-3,3'-dimethoxy-5,5'-dipropyldiphenylmethane 0
                                            2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-7H-pyrano[2,3-g][1,4]benzodioxin-7-one 0
                                            2-hydroxy-6-[2-(3,4-dihydroxyphenyl-5-methoxy)-2-oxoethyl]benzoic acid 0
                                            2-methoxy-6-(all-trans-polyprenyl)phenol + 0
                                            2-methoxyresorcinol sulfate 0
                                            3,3''-dihydroxy-6'-O-desmethylterphenyllin 0
                                            3-hydroxy-6'-O-desmethylterphenyllin 0
                                            4'-O-methylnorbelladine 0
                                            4,6-dinitroguaiacol 0
                                            4-(1-hydroxypropyl)-2-methoxy-6-(2-methoxy-4-propylphenoxy)phenol 0
                                            4-hydroxy-3-methoxybenzene-1-sulfonic acid 0
                                            4-hydroxy-3-methoxycinnamoylagmatine + 0
                                            4alpha-hydroxypinoresinol 0
                                            4beta-[(beta-D-glucopyranosyl)hydroxy]-pinoresinol 0
                                            5-O-desmethyldonepezil 0
                                            5-hydroxyconiferyl alcohol + 0
                                            6'',7''-dihydro-5',5'''-dicapsaicin 0
                                            6'-O-desmethylterphenyllin 0
                                            7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-4E-heptene-3-one 0
                                            7-(4''-hydroxy-3''-methoxyphenyl)-5-methoxy-1-phenyl-3-heptanone 0
                                            Cuscuta propenamide 2 0
                                            N-octylhomovanillamide 0
                                            N-trans-feruloyl-4'-O-methyldopamine 0
                                            NK372135C 0
                                            buddlenol E 0
                                            coniferol 0
                                            coniferyl aldehyde 22
                                            coniferyl benzoate 0
                                            coniferyl p-coumarate 0
                                            dehydrodiconiferyl alcohol + 0
                                            dichotomoside D 0
                                            dihydroferulic acid 0
                                            gingerenone B 0
                                            gingerol 80
                                            glycosmisic acid + 0
                                            glycosmisic acid sulfate 0
                                            guaiacol 6
                                            guaiacylglycerol + 0
                                            homoeriodictyol chalcone 0
                                            homovanillic acid 11
                                            isorhapontigenin 19
                                            isosilybin 9
                                            kadsurenin K 0
                                            lamellarin alpha 20-hydrogen sulfate 0
                                            matairesinoside 0
                                            meso-dihydroguaiaretic acid 0
                                            negundin B 0
                                            ortho-vanillin 1
                                            pinoresinol + 7
                                            rhapontigenin 3
                                            salicifoliol 0
                                            tanegool 0
                                            taxiresinol 0
                                            threo-1-(4-hydroxy-3-methoxyphenyl)-2-\{4-[-(E)-3-hydroxy-1-propenyl]-2-methoxyphenoxy\}-1,3-propanediol 0
                                            trans-methylferulate 0
                                            triptohypol A 0
                                            vanillyl alcohol 1
                                            vanillyl beta-D-glucopyranoside 0
                                            vladinol D 0
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