CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: graphene oxide
Accession: CHEBI:132889
browse the term
Definition: A single carbon layer of the graphite oxide structure.
Synonyms: related_synonym: GO
xref_mesh: MESH:C000628730
xref: PMCID:PMC8540551; PMCID:PMC8582055; PMCID:PMC8585176; PMID:20023850; PMID:33668189; PMID:34270266; PMID:34327598; PMID:34371431; PMID:34443964; PMID:34668901
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Abca1
ATP binding cassette subfamily A member 1
decreases expression
ISO
graphene oxide results in decreased expression of ABCA1 mRNA
CTD
PMID:33227293
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcg1
ATP binding cassette subfamily G member 1
decreases expression
ISO
graphene oxide results in decreased expression of ABCG1 mRNA
CTD
PMID:33227293
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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Acot1
acyl-CoA thioesterase 1
decreases expression
ISO
graphene oxide results in decreased expression of ACOT1 mRNA
CTD
PMID:33227293
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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Acsl3
acyl-CoA synthetase long-chain family member 3
increases expression
ISO
graphene oxide results in increased expression of ACSL3 protein
CTD
PMID:33221320
NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acta2
actin alpha 2, smooth muscle
decreases expression
ISO
graphene oxide analog results in decreased expression of ACTA2 mRNA
CTD
PMID:33227293
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Adamts4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
increases expression
ISO
graphene oxide results in increased expression of ADAMTS4 mRNA
CTD
PMID:33227293
NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Ager
advanced glycosylation end product-specific receptor
multiple interactions
ISO
[[graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein; [graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein
CTD
PMID:31504961
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Agxt2
alanine-glyoxylate aminotransferase 2
decreases expression
ISO
graphene oxide results in decreased expression of AGXT2 mRNA
CTD
PMID:33227293
NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
decreases expression
ISO
graphene oxide results in decreased expression of ALDH1A1 mRNA
CTD
PMID:33227293
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Angptl4
angiopoietin-like 4
increases expression
ISO
graphene oxide results in increased expression of ANGPTL4 mRNA
CTD
PMID:33227293
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Apoa2
apolipoprotein A2
increases expression
ISO
graphene oxide analog results in increased expression of APOA2 mRNA
CTD
PMID:33227293
NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
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Apobec3
apolipoprotein B mRNA editing enzyme catalytic subunit 3
increases expression
ISO
graphene oxide analog results in increased expression of APOBEC3 mRNA
CTD
PMID:33227293
NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922
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Aqp8
aquaporin 8
decreases expression
ISO
graphene oxide results in decreased expression of AQP8 mRNA
CTD
PMID:33227293
NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
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Arg1
arginase 1
increases expression
ISO
graphene oxide results in increased expression of ARG1 mRNA
CTD
PMID:33227293
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Asgr1
asialoglycoprotein receptor 1
decreases expression
ISO
graphene oxide results in decreased expression of ASGR1 mRNA
CTD
PMID:33227293
NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
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Atf4
activating transcription factor 4
increases expression
ISO
graphene oxide results in increased expression of ATF4 mRNA
CTD
PMID:33973267
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Bax
BCL2 associated X, apoptosis regulator
increases expression affects expression
ISO
graphene oxide results in increased expression of BAX protein graphene oxide affects the expression of BAX mRNA
CTD
PMID:30239936 PMID:32070776
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
graphene oxide results in decreased expression of BCL2 mRNA; graphene oxide results in decreased expression of BCL2 protein
CTD
PMID:30239936 PMID:32070776
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Becn1
beclin 1
multiple interactions increases expression
ISO
dorsomorphin inhibits the reaction [graphene oxide results in increased expression of BECN1 protein]
CTD
PMID:32430275
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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Bmal1
basic helix-loop-helix ARNT like 1
decreases expression
ISO
graphene oxide analog results in decreased expression of BMAL1 mRNA; graphene oxide results in decreased expression of BMAL1 mRNA
CTD
PMID:33227293
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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Bmp1
bone morphogenetic protein 1
increases expression
ISO
graphene oxide results in increased expression of BMP1 protein
CTD
PMID:33219560 PMID:33219569
NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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Cabp5
calcium binding protein 5
decreases expression
ISO
graphene oxide analog results in decreased expression of CABP5 mRNA; graphene oxide results in decreased expression of CABP5 mRNA
CTD
PMID:33227293
NCBI chr 1:74,350,811...74,363,830
Ensembl chr 1:74,350,811...74,363,830
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Ccdc28a
coiled-coil domain containing 28A
increases expression
ISO
graphene oxide results in increased expression of CCDC28A protein
CTD
PMID:33219560 PMID:33219562
NCBI chr 1:12,857,668...12,872,944
Ensembl chr 1:12,857,666...12,873,003
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Ccl11
C-C motif chemokine ligand 11
increases expression
ISO
graphene oxide results in increased expression of CCL11 mRNA
CTD
PMID:33227293
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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Ccl17
C-C motif chemokine ligand 17
increases expression
ISO
graphene oxide analog results in increased expression of CCL17 mRNA; graphene oxide results in increased expression of CCL17 mRNA
CTD
PMID:33227293
NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
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Ccl19
C-C motif chemokine ligand 19
increases expression
ISO
graphene oxide analog results in increased expression of CCL19 mRNA; graphene oxide results in increased expression of CCL19 mRNA
CTD
PMID:33227293
NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
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Ccl2
C-C motif chemokine ligand 2
increases expression
ISO
graphene oxide results in increased expression of CCL2 mRNA
CTD
PMID:33227293
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl24
C-C motif chemokine ligand 24
increases expression
ISO
graphene oxide results in increased expression of CCL24 mRNA
CTD
PMID:33227293
NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
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Ccl25
C-C motif chemokine ligand 25
increases expression
ISO
graphene oxide results in increased expression of CCL25 mRNA
CTD
PMID:33227293
NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554
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Ccl27
C-C motif chemokine ligand 27
increases expression
ISO
graphene oxide analog results in increased expression of CCL27A mRNA; graphene oxide results in increased expression of CCL27A mRNA
CTD
PMID:33227293
NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
graphene oxide results in increased expression of CCL3L3 mRNA
CTD
PMID:33227293
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
graphene oxide results in increased expression of CCL4 mRNA
CTD
PMID:33227293
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccl5
C-C motif chemokine ligand 5
increases expression
ISO
graphene oxide analog results in increased expression of CCL5 mRNA
CTD
PMID:33227293
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
graphene oxide results in increased expression of CCL7 mRNA
CTD
PMID:33227293
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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Ccl9
C-C motif chemokine ligand 9
increases expression
ISO
graphene oxide analog results in increased expression of CCL6 mRNA; graphene oxide results in increased expression of CCL6 mRNA
CTD
PMID:33227293
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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Ccnd1
cyclin D1
decreases expression
ISO
graphene oxide results in decreased expression of CCND1 mRNA
CTD
PMID:33227293
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccr5
C-C motif chemokine receptor 5
increases expression
ISO
graphene oxide results in increased expression of CCR5 mRNA
CTD
PMID:33227293
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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Cd14
CD14 molecule
increases expression
ISO
graphene oxide results in increased expression of CD14 mRNA
CTD
PMID:33227293
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cfd
complement factor D
increases expression
ISO
graphene oxide results in increased expression of CFD protein
CTD
PMID:33219560
NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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Ch25h
cholesterol 25-hydroxylase
increases expression
ISO
graphene oxide analog results in increased expression of CH25H mRNA; graphene oxide results in increased expression of CH25H mRNA
CTD
PMID:33227293
NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
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Chka
choline kinase alpha
decreases expression
ISO
graphene oxide results in decreased expression of CHKA mRNA
CTD
PMID:33227293
NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
decreases expression
ISO
graphene oxide results in decreased expression of CHUK protein
CTD
PMID:30239936
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Cidec
cell death-inducing DFFA-like effector c
increases expression
ISO
graphene oxide results in increased expression of CIDEC mRNA
CTD
PMID:33227293
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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Ckm
creatine kinase, M-type
increases expression
ISO
graphene oxide results in increased expression of CKM protein
CTD
PMID:33219560 PMID:33219579
NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
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Clpx
caseinolytic mitochondrial matrix peptidase chaperone subunit X
decreases expression
ISO
graphene oxide results in decreased expression of CLPX mRNA
CTD
PMID:33227293
NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
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Cnfn
cornifelin
decreases expression
ISO
graphene oxide results in decreased expression of CNFN mRNA
CTD
PMID:33227293
NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747
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Cnn1
calponin 1
decreases expression
ISO
graphene oxide analog results in decreased expression of CNN1 mRNA
CTD
PMID:33227293
NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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Col4a3
collagen type IV alpha 3 chain
increases expression
ISO
graphene oxide analog results in increased expression of COL4A3 mRNA
CTD
PMID:33227293
NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895
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Colq
collagen like tail subunit of asymmetric acetylcholinesterase
decreases expression
ISO
graphene oxide results in decreased expression of COLQ mRNA
CTD
PMID:33227293
NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
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Cplx2
complexin 2
decreases expression
ISO
graphene oxide analog results in decreased expression of CPLX2 mRNA; graphene oxide results in decreased expression of CPLX2 mRNA
CTD
PMID:33227293
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
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Cr2
complement C3d receptor 2
decreases expression
ISO
graphene oxide results in decreased expression of CR2 mRNA
CTD
PMID:33227293
NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235
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Creld2
cysteine-rich with EGF-like domains 2
decreases expression
ISO
graphene oxide analog results in decreased expression of CRELD2 mRNA
CTD
PMID:33227293
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
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Crim1
cysteine rich transmembrane BMP regulator 1
increases expression
ISO
graphene oxide results in increased expression of CRIM1 protein
CTD
PMID:33219560 PMID:33219575
NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
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Crybb3
crystallin, beta B3
increases expression
ISO
graphene oxide results in increased expression of CRYBB3 mRNA
CTD
PMID:33227293
NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120
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Ctss
cathepsin S
increases expression
ISO
graphene oxide analog results in increased expression of CTSS mRNA; graphene oxide results in increased expression of CTSS mRNA
CTD
PMID:33227293
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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Cx3cl1
C-X3-C motif chemokine ligand 1
decreases expression
ISO
graphene oxide results in decreased expression of CX3CL1 mRNA
CTD
PMID:33227293
NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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Cxcl10
C-X-C motif chemokine ligand 10
increases expression
ISO
graphene oxide results in increased expression of CXCL10 mRNA
CTD
PMID:33227293
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cxcl11
C-X-C motif chemokine ligand 11
decreases expression
ISO
graphene oxide analog results in decreased expression of CXCL11 mRNA; graphene oxide results in decreased expression of CXCL11 mRNA
CTD
PMID:33227293
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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Cxcl12
C-X-C motif chemokine ligand 12
increases expression
ISO
graphene oxide results in increased expression of CXCL12 mRNA
CTD
PMID:33227293
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cxcl13
C-X-C motif chemokine ligand 13
increases expression
ISO
graphene oxide results in increased expression of CXCL13 mRNA
CTD
PMID:33227293
NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
graphene oxide results in increased expression of CXCL2 mRNA
CTD
PMID:33227293
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cxcl3
C-X-C motif chemokine ligand 3
increases expression
ISO
graphene oxide results in increased expression of CXCL3 mRNA
CTD
PMID:33227293
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcl6
C-X-C motif chemokine ligand 6
increases expression
ISO
graphene oxide results in increased expression of CXCL5 mRNA; graphene oxide results in increased expression of CXCL6 mRNA
CTD
PMID:33227293
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases expression
ISO
graphene oxide results in increased expression of CYP7A1 mRNA
CTD
PMID:33227293
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Dbp
D-box binding PAR bZIP transcription factor
increases expression
ISO
graphene oxide analog results in increased expression of DBP mRNA; graphene oxide results in increased expression of DBP mRNA
CTD
PMID:33227293
NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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Dcaf12l2
DDB1 and CUL4 associated factor 12-like 2
decreases expression
ISO
graphene oxide analog results in decreased expression of DCAF12L2 mRNA
CTD
PMID:33227293
NCBI chr X:123,293,761...123,296,550
Ensembl chr X:123,294,744...123,296,156
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Ddx17
DEAD-box helicase 17
decreases expression
ISO
graphene oxide results in decreased expression of DDX17 mRNA
CTD
PMID:33227293
NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
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Dnah6
dynein, axonemal, heavy chain 6
decreases expression
ISO
graphene oxide results in decreased expression of DNAH6 mRNA
CTD
PMID:33227293
NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376
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Efcab3
EF-hand calcium binding domain 3
increases expression
ISO
graphene oxide results in increased expression of EFCAB3 mRNA
CTD
PMID:29348435
NCBI chr10:89,583,526...90,077,260
Ensembl chr10:89,644,522...90,077,259
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Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
increases expression
ISO
graphene oxide results in increased expression of EIF4EBP3 mRNA
CTD
PMID:33227293
NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024
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Elovl3
ELOVL fatty acid elongase 3
decreases expression
ISO
graphene oxide results in decreased expression of ELOVL3 mRNA
CTD
PMID:33227293
NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
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Fabp5
fatty acid binding protein 5
decreases expression
ISO
graphene oxide results in decreased expression of FABP5 mRNA
CTD
PMID:33227293
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
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Fasn
fatty acid synthase
increases expression
ISO
graphene oxide results in increased expression of FASN protein
CTD
PMID:33221320
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fbxo11
F-box protein 11
increases expression
ISO
graphene oxide results in increased expression of FBXO11 protein
CTD
PMID:33219560 PMID:33219567
NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662
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Fcgr2b
Fc gamma receptor 2B
increases expression
ISO
graphene oxide analog results in increased expression of FCGR2B mRNA; graphene oxide results in increased expression of FCGR2B mRNA
CTD
PMID:33227293
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
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Fgg
fibrinogen gamma chain
increases expression
ISO
graphene oxide results in increased expression of FGG mRNA
CTD
PMID:33227293
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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Fkbp5
FKBP prolyl isomerase 5
increases expression
ISO
graphene oxide results in increased expression of FKBP5 mRNA
CTD
PMID:33227293
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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Fmo3
flavin containing dimethylaniline monoxygenase 3
decreases expression
ISO
graphene oxide analog results in decreased expression of FMO3 mRNA; graphene oxide results in decreased expression of FMO3 mRNA
CTD
PMID:33227293
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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Fn1
fibronectin 1
increases expression
ISO
graphene oxide results in increased expression of FN1 protein
CTD
PMID:33219560 PMID:33219561
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fus
Fus RNA binding protein
decreases expression
ISO
graphene oxide results in decreased expression of FUS protein
CTD
PMID:33219560
NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
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Fxyd4
FXYD domain-containing ion transport regulator 4
increases expression
ISO
graphene oxide results in increased expression of FXYD4 mRNA
CTD
PMID:33227293
NCBI chr 4:151,109,779...151,113,659
Ensembl chr 4:151,109,779...151,113,637
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Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
ISO
graphene oxide analog results in increased expression of GADD45G mRNA
CTD
PMID:33227293
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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Galnt15
polypeptide N-acetylgalactosaminyltransferase 15
decreases expression
ISO
graphene oxide results in decreased expression of GALNT15 mRNA
CTD
PMID:33227293
NCBI chr16:7,227,232...7,267,002
Ensembl chr16:7,227,271...7,267,014
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Gbp6
guanylate binding protein family member 6
decreases expression
ISO
graphene oxide results in decreased expression of GBP6 mRNA
CTD
PMID:33227293
NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062 Ensembl chr14:4,730,453...4,839,062
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Gdf15
growth differentiation factor 15
decreases expression
ISO
graphene oxide results in decreased expression of GDF15 mRNA
CTD
PMID:33227293
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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Grb7
growth factor receptor bound protein 7
increases expression
ISO
graphene oxide results in increased expression of GRB7 protein
CTD
PMID:33219560 PMID:33219570
NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
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Gsdmd
gasdermin D
increases expression
ISO
graphene oxide results in increased expression of GSDMD mRNA
CTD
PMID:33973267
NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055
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Gsta2
glutathione S-transferase alpha 2
decreases expression
ISO
graphene oxide results in decreased expression of GSTA2 mRNA
CTD
PMID:33227293
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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Gulp1
GULP PTB domain containing engulfment adaptor 1
increases expression
ISO
graphene oxide results in increased expression of GULP1 protein
CTD
PMID:33219560 PMID:33219585
NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
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Habp2
hyaluronan binding protein 2
increases expression
ISO
graphene oxide results in increased expression of HABP2 protein
CTD
PMID:33219560 PMID:33219584
NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160
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Hao2
hydroxyacid oxidase 2
decreases expression
ISO
graphene oxide results in decreased expression of HAO2 mRNA
CTD
PMID:33227293
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
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Hmgb1
high mobility group box 1
increases secretion multiple interactions
ISO
graphene oxide results in increased secretion of HMGB1 protein 2',3'-dialdehyde ATP inhibits the reaction [graphene oxide results in increased secretion of HMGB1 protein]; [[graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein; [graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein; Adenosine Triphosphate promotes the reaction [graphene oxide results in increased secretion of HMGB1 protein]; graphene oxide results in increased localization of and results in increased secretion of HMGB1 protein; P2RX7 protein affects the reaction [graphene oxide results in increased secretion of HMGB1 protein]
CTD
PMID:31504961
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
graphene oxide analog results in decreased expression of HSPA5 mRNA
CTD
PMID:33227293
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Htra1
HtrA serine peptidase 1
increases expression
ISO
graphene oxide results in increased expression of HTRA1 protein
CTD
PMID:33219560 PMID:33219581
NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
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Icam1
intercellular adhesion molecule 1
increases secretion
ISO
graphene oxide results in increased secretion of ICAM1 protein
CTD
PMID:33973267
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Igfbp3
insulin-like growth factor binding protein 3
increases expression
ISO
graphene oxide results in increased expression of IGFBP3 protein
CTD
PMID:33219560
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Igfbp4
insulin-like growth factor binding protein 4
increases expression
ISO
graphene oxide results in increased expression of IGFBP4 protein
CTD
PMID:33219560 PMID:33219572
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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Igfbp7
insulin-like growth factor binding protein 7
increases expression
ISO
graphene oxide results in increased expression of IGFBP7 protein
CTD
PMID:33219560 PMID:33219563
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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Igsf10
immunoglobulin superfamily, member 10
decreases expression
ISO
graphene oxide results in decreased expression of IGSF10 mRNA
CTD
PMID:33227293
NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773
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Il11
interleukin 11
increases expression
ISO
graphene oxide results in increased expression of IL11 mRNA
CTD
PMID:33227293
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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Il16
interleukin 16
increases expression
ISO
graphene oxide analog results in increased expression of IL16 mRNA; graphene oxide results in increased expression of IL16 mRNA
CTD
PMID:33227293
NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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Il18
interleukin 18
increases expression
ISO
graphene oxide analog results in increased expression of IL18 mRNA; graphene oxide results in increased expression of IL18 mRNA
CTD
PMID:33227293
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1b
interleukin 1 beta
increases expression
ISO
graphene oxide analog results in increased expression of IL1B mRNA; graphene oxide results in increased expression of IL1B mRNA
CTD
PMID:33227293
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1rn
interleukin 1 receptor antagonist
increases expression
ISO
graphene oxide results in increased expression of IL1RN mRNA
CTD
PMID:33227293
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il33
interleukin 33
increases expression
ISO
graphene oxide analog results in increased expression of IL33 mRNA; graphene oxide results in increased expression of IL33 mRNA
CTD
PMID:33227293
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
decreases expression
ISO
graphene oxide results in decreased expression of IRAK1BP1 mRNA
CTD
PMID:33227293
NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
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Ireb2
iron responsive element binding protein 2
increases expression
ISO
graphene oxide results in increased expression of IREB2 protein
CTD
PMID:33219560 PMID:33219583
NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
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Itgb2
integrin subunit beta 2
increases expression
ISO
graphene oxide analog results in increased expression of ITGB2 mRNA; graphene oxide results in increased expression of ITGB2 mRNA
CTD
PMID:33227293
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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Klf10
KLF transcription factor 10
increases expression
ISO
graphene oxide analog results in increased expression of KLF10 mRNA
CTD
PMID:33227293
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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Krtap17-1
keratin associated protein 17-1
decreases expression
ISO
graphene oxide results in decreased expression of KRTAP17-1 mRNA
CTD
PMID:33227293
NCBI chr10:84,923,920...84,924,634
Ensembl chr10:84,923,922...84,924,634
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Lbp
lipopolysaccharide binding protein
increases expression
ISO
graphene oxide results in increased expression of LBP mRNA
CTD
PMID:33227293
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
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Lcn2
lipocalin 2
increases expression
ISO
graphene oxide results in increased expression of LCN2 mRNA
CTD
PMID:33227293
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Ldha
lactate dehydrogenase A
increases activity
ISO
graphene oxide results in increased activity of LDHA protein
CTD
PMID:25996036
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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Ldlr
low density lipoprotein receptor
increases expression
ISO
graphene oxide results in increased expression of LDLR mRNA
CTD
PMID:33227293
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lilrb4
leukocyte immunoglobulin like receptor B4
increases expression
ISO
graphene oxide analog results in increased expression of LILRB4 mRNA
CTD
PMID:33227293
NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
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Lonrf3
LON peptidase N-terminal domain and ring finger 3
decreases expression
ISO
graphene oxide analog results in decreased expression of LONRF3 mRNA
CTD
PMID:33227293
NCBI chr X:115,565,214...115,603,886
Ensembl chr X:115,565,267...115,598,809
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Loxl2
lysyl oxidase-like 2
increases expression
ISO
graphene oxide results in increased expression of LOXL2 protein
CTD
PMID:33219560 PMID:33219578
NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
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Loxl4
lysyl oxidase-like 4
decreases expression
ISO
graphene oxide analog results in decreased expression of LOXL4 mRNA
CTD
PMID:33227293
NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
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Lpxn
leupaxin
increases expression
ISO
graphene oxide results in increased expression of LPXN mRNA
CTD
PMID:33227293
NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
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Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
decreases expression
ISO
graphene oxide analog results in decreased expression of LRFN3 mRNA
CTD
PMID:33227293
NCBI chr 1:85,616,862...85,623,725
Ensembl chr 1:85,616,868...85,623,725
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Lrrc51
leucine rich repeat containing 51
decreases expression
ISO
graphene oxide results in decreased expression of LRRC51 mRNA
CTD
PMID:33227293
NCBI chr 1:156,278,617...156,297,838
Ensembl chr 1:156,278,618...156,297,773
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Ly86
lymphocyte antigen 86
affects expression
ISO
graphene oxide affects the expression of LY86 mRNA
CTD
PMID:33227293
NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260
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Lzts3
leucine zipper tumor suppressor family member 3
decreases expression
ISO
graphene oxide analog results in decreased expression of LZTS3 mRNA
CTD
PMID:33227293
NCBI chr 3:117,850,286...117,861,132
Ensembl chr 3:117,851,702...117,860,081
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Mamdc2
MAM domain containing 2
decreases expression
ISO
graphene oxide results in decreased expression of MAMDC2 mRNA
CTD
PMID:33227293
NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:220,863,976...221,016,354
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Map3k6
mitogen-activated protein kinase kinase kinase 6
increases expression
ISO
graphene oxide results in increased expression of MAP3K6 mRNA
CTD
PMID:33227293
NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212
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Meg3
maternally expressed 3
increases expression
ISO
graphene oxide analog results in increased expression of MEG3 mRNA
CTD
PMID:33227293
NCBI chr 6:128,491,808...128,524,010
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Mir21
microRNA 21
affects expression
ISO
graphene oxide affects the expression of MIR21 mRNA
CTD
PMID:32070776
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir29a
microRNA 29a
affects expression
ISO
graphene oxide affects the expression of MIR29A mRNA
CTD
PMID:32070776
NCBI chr 4:59,650,608...59,650,695
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Mmp14
matrix metallopeptidase 14
increases expression
ISO
graphene oxide results in increased expression of MMP14 mRNA
CTD
PMID:33227293
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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Mmp19
matrix metallopeptidase 19
increases expression
ISO
graphene oxide results in increased expression of MMP19 mRNA
CTD
PMID:33227293
NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555
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Mmp2
matrix metallopeptidase 2
increases expression
ISO
graphene oxide results in increased expression of MMP2 mRNA
CTD
PMID:31504961
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
graphene oxide results in increased expression of MMP3 mRNA
CTD
PMID:33227293
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp8
matrix metallopeptidase 8
increases expression
ISO
graphene oxide results in increased expression of MMP8 mRNA
CTD
PMID:33227293
NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
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Mmp9
matrix metallopeptidase 9
increases expression
ISO
graphene oxide results in increased expression of MMP9 mRNA
CTD
PMID:33227293
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mt-nd1
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
decreases expression
ISO
graphene oxide analog results in decreased expression of ND1 mRNA
CTD
PMID:33227293
NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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Mt1
metallothionein 1
increases expression
ISO
graphene oxide results in increased expression of MT1 mRNA
CTD
PMID:33227293
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A
metallothionein 2A
increases expression
ISO
graphene oxide results in increased expression of MT2 mRNA
CTD
PMID:33227293
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mtor
mechanistic target of rapamycin kinase
decreases phosphorylation multiple interactions
ISO
graphene oxide results in decreased phosphorylation of MTOR protein dorsomorphin inhibits the reaction [graphene oxide results in decreased phosphorylation of MTOR protein]
CTD
PMID:32430275
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Mup18
major urinary protein 18
increases expression
ISO
graphene oxide analog results in increased expression of MUP18 mRNA
CTD
PMID:33227293
NCBI chr 5:74,986,813...74,990,071
Ensembl chr 5:74,842,319...75,061,474
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Mycbp2
MYC binding protein 2
increases expression
ISO
graphene oxide results in increased expression of MYCBP2 protein
CTD
PMID:33219560 PMID:33219574
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
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Myd88
MYD88, innate immune signal transduction adaptor
increases expression
ISO
graphene oxide results in increased expression of MYD88 mRNA
CTD
PMID:33227293
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Myl9
myosin light chain 9
decreases expression
ISO
graphene oxide analog results in decreased expression of MYL9 mRNA
CTD
PMID:33227293
NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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Myom3
myomesin 3
increases expression
ISO
graphene oxide results in increased expression of MYOM3 mRNA
CTD
PMID:33227293
NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274
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Nfkbia
NFKB inhibitor alpha
increases expression
ISO
graphene oxide results in increased expression of NFKBIA protein
CTD
PMID:30239936
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nhs
NHS actin remodeling regulator
increases expression
ISO
graphene oxide results in increased expression of NHS protein
CTD
PMID:33219560 PMID:33219577
NCBI chr X:32,553,300...32,892,961
Ensembl chr X:32,552,026...32,889,992
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Nlrp3
NLR family, pyrin domain containing 3
increases expression
ISO
graphene oxide results in increased expression of NLRP3 mRNA
CTD
PMID:33973267
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Noct
nocturnin
increases expression
ISO
graphene oxide results in increased expression of NOCT mRNA
CTD
PMID:33227293
NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
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Nr0b2
nuclear receptor subfamily 0, group B, member 2
decreases expression
ISO
graphene oxide results in decreased expression of NR0B2 mRNA
CTD
PMID:33227293
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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Nrg4
neuregulin 4
increases expression
ISO
graphene oxide results in increased expression of NRG4 mRNA
CTD
PMID:33227293
NCBI chr 8:55,586,253...55,677,829
Ensembl chr 8:55,592,893...55,677,483
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Ntn4
netrin 4
increases expression
ISO
graphene oxide results in increased expression of NTN4 protein
CTD
PMID:33219560 PMID:33219580
NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
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Ogn
osteoglycin
decreases expression
ISO
graphene oxide results in decreased expression of OGN mRNA
CTD
PMID:33227293
NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739
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P2rx7
purinergic receptor P2X 7
multiple interactions
ISO
P2RX7 protein affects the reaction [graphene oxide results in increased secretion of HMGB1 protein]
CTD
PMID:31504961
NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
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Pax2
paired box 2
decreases expression
ISO
graphene oxide analog results in decreased expression of PAX2 mRNA
CTD
PMID:33227293
NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
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Pcdhga9
protocadherin gamma subfamily A, 9
decreases expression
ISO
graphene oxide results in decreased expression of PCDHGA9 mRNA
CTD
PMID:33227293
NCBI chr18:29,564,614...29,667,865
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Pde6c
phosphodiesterase 6C
increases expression
ISO
graphene oxide results in increased expression of PDE6C mRNA
CTD
PMID:29348435
NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
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Pdk4
pyruvate dehydrogenase kinase 4
decreases expression
ISO
graphene oxide results in decreased expression of PDK4 mRNA
CTD
PMID:33227293
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
increases expression
ISO
graphene oxide results in increased expression of PIP5K1A mRNA
CTD
PMID:33227293
NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
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Plau
plasminogen activator, urokinase
increases expression
ISO
graphene oxide results in increased expression of PLAU protein
CTD
PMID:33219560 PMID:33219568
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Plin4
perilipin 4
increases expression
ISO
graphene oxide results in increased expression of PLIN4 mRNA
CTD
PMID:33227293
NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
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Pon1
paraoxonase 1
decreases expression
ISO
graphene oxide results in decreased expression of PON1 mRNA
CTD
PMID:33227293
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Ppard
peroxisome proliferator-activated receptor delta
increases expression
ISO
graphene oxide analog results in increased expression of PPARD mRNA
CTD
PMID:33227293
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Ppbp
pro-platelet basic protein
decreases expression
ISO
graphene oxide results in decreased expression of PPBP mRNA
CTD
PMID:33227293
NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
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Prnp
prion protein
decreases expression
ISO
graphene oxide results in decreased expression of PRNP protein
CTD
PMID:33219560
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Prok1
prokineticin 1
decreases expression
ISO
graphene oxide results in decreased expression of PROK1 mRNA
CTD
PMID:33227293
NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250
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Pten
phosphatase and tensin homolog
increases expression decreases expression
ISO
graphene oxide results in increased expression of PTEN protein graphene oxide results in decreased expression of PTEN mRNA
CTD
PMID:32070776
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Qsox1
quiescin sulfhydryl oxidase 1
increases expression
ISO
graphene oxide results in increased expression of QSOX1 protein
CTD
PMID:33219560
NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
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Rac1
Rac family small GTPase 1
multiple interactions
ISO
[[graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein
CTD
PMID:31504961
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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Rnf186
ring finger protein 186
decreases expression
ISO
graphene oxide results in decreased expression of RNF186 mRNA
CTD
PMID:33227293
NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716
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Rs1
retinoschisin 1
decreases expression
ISO
graphene oxide analog results in decreased expression of RS1 mRNA
CTD
PMID:33227293
NCBI chr X:33,962,440...33,992,203
Ensembl chr X:33,963,657...33,992,115
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Rsrc2
arginine and serine rich coiled-coil 2
decreases expression
ISO
graphene oxide results in decreased expression of RSRC2 protein
CTD
PMID:33219560
NCBI chr12:32,839,840...32,859,820
Ensembl chr12:32,839,809...32,859,799
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Rsrp1
arginine and serine rich protein 1
increases expression
ISO
graphene oxide analog results in increased expression of RSRP1 mRNA
CTD
PMID:33227293
NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
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S100a4
S100 calcium-binding protein A4
increases expression
ISO
graphene oxide results in increased expression of S100A4 mRNA
CTD
PMID:33227293
NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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S100a8
S100 calcium binding protein A8
increases expression
ISO
graphene oxide analog results in increased expression of S100A8 mRNA
CTD
PMID:33227293
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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Sarm1
sterile alpha and TIR motif containing 1
increases expression
ISO
graphene oxide results in increased expression of SARM1 protein
CTD
PMID:33219560
NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822
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Serf1
small EDRK-rich factor 1
decreases expression
ISO
graphene oxide results in decreased expression of SERF1 mRNA
CTD
PMID:33227293
NCBI chr 2:31,475,902...31,482,030
Ensembl chr 2:31,475,703...31,482,032
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Serpina3n
serpin family A member 3N
increases expression
ISO
graphene oxide results in increased expression of SERPINA3N mRNA
CTD
PMID:33227293
NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
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Shc4
SHC adaptor protein 4
decreases expression
ISO
graphene oxide analog results in decreased expression of SHC4 mRNA
CTD
PMID:33227293
NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:112,880,600...112,974,366
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Slc26a4
solute carrier family 26 member 4
increases expression
ISO
graphene oxide analog results in increased expression of SLC26A4 mRNA; graphene oxide results in increased expression of SLC26A4 mRNA
CTD
PMID:33227293
NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
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Slc30a7
solute carrier family 30 member 7
decreases expression
ISO
graphene oxide analog results in decreased expression of SLC30A7 mRNA
CTD
PMID:33227293
NCBI chr 2:203,855,484...203,922,155
Ensembl chr 2:203,859,175...203,922,132
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Smarca4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
increases expression
ISO
graphene oxide results in increased expression of SMARCA4 mRNA
CTD
PMID:33219560 PMID:33219585
NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
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Snhg11
small nucleolar RNA host gene 11
increases expression
ISO
graphene oxide analog results in increased expression of SNHG11 mRNA
CTD
PMID:33227293
NCBI chr 3:147,031,367...147,037,043
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Sox4
SRY-box transcription factor 4
decreases expression
ISO
graphene oxide results in decreased expression of SOX4 mRNA
CTD
PMID:33227293
NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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Spon2
spondin 2
decreases expression
ISO
graphene oxide results in decreased expression of SPON2 mRNA
CTD
PMID:33227293
NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
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Sqstm1
sequestosome 1
multiple interactions decreases expression
ISO
dorsomorphin inhibits the reaction [graphene oxide results in decreased expression of SQSTM1 protein]
CTD
PMID:32430275
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srsf10
serine and arginine rich splicing factor 10
decreases expression
ISO
graphene oxide results in decreased expression of SRSF10 protein
CTD
PMID:33219560
NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
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Srsf11
serine and arginine rich splicing factor 11
decreases expression
ISO
graphene oxide results in decreased expression of SRSF11 protein
CTD
PMID:33219560
NCBI chr 2:247,074,623...247,101,460
Ensembl chr 2:247,074,631...247,101,425
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Srsf4
serine and arginine rich splicing factor 4
decreases expression
ISO
graphene oxide results in decreased expression of SRSF4 protein
CTD
PMID:33219560
NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:144,061,463...144,089,229
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St6galnac1
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
decreases expression
ISO
graphene oxide analog results in decreased expression of ST6GALNAC1 mRNA
CTD
PMID:33227293
NCBI chr10:101,972,656...101,983,053
Ensembl chr10:101,972,668...101,983,053
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Sult1e1
sulfotransferase family 1E member 1
increases expression
ISO
graphene oxide results in increased expression of SULT1E1 mRNA
CTD
PMID:33227293
NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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Syt10
synaptotagmin 10
decreases expression
ISO
graphene oxide analog results in decreased expression of SYT10 mRNA
CTD
PMID:33227293
NCBI chr 7:120,857,698...120,920,863
Ensembl chr 7:120,862,972...120,920,863
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Taf15
TATA-box binding protein associated factor 15
decreases expression
ISO
graphene oxide results in decreased expression of TAF15 protein
CTD
PMID:33219560
NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949
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Tbk1
TANK-binding kinase 1
increases expression
ISO
graphene oxide results in increased expression of TBK1 mRNA
CTD
PMID:33227293
NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
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Tdrd7
tudor domain containing 7
increases expression
ISO
graphene oxide results in increased expression of TDRD7 protein
CTD
PMID:33219560 PMID:33219571
NCBI chr 5:60,238,742...60,312,548
Ensembl chr 5:60,238,678...60,312,544
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Tef
TEF transcription factor, PAR bZIP family member
increases expression
ISO
graphene oxide analog results in increased expression of TEF mRNA
CTD
PMID:33227293
NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
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Tfpi
tissue factor pathway inhibitor
increases expression
ISO
graphene oxide results in increased expression of TFPI protein
CTD
PMID:33219560 PMID:33219565
NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
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Tgfb1
transforming growth factor, beta 1
increases expression
ISO
graphene oxide results in increased expression of TGFB1 mRNA
CTD
PMID:33219560 PMID:33219585
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbi
transforming growth factor, beta induced
increases expression
ISO
graphene oxide results in increased expression of TGFBI protein
CTD
PMID:33219560 PMID:33219582
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
graphene oxide analog results in increased expression of TIMP1 mRNA; graphene oxide results in increased expression of TIMP1 mRNA
CTD
PMID:33227293
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp2
TIMP metallopeptidase inhibitor 2
decreases expression
ISO
graphene oxide results in decreased expression of TIMP2 mRNA
CTD
PMID:31504961
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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Tirap
TIR domain containing adaptor protein
increases expression
ISO
graphene oxide results in increased expression of TIRAP mRNA
CTD
PMID:33227293
NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
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Tlr1
toll-like receptor 1
increases expression
ISO
graphene oxide analog results in increased expression of TLR1 mRNA
CTD
PMID:33227293
NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
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Tlr2
toll-like receptor 2
increases expression
ISO
graphene oxide analog results in increased expression of TLR2 mRNA
CTD
PMID:33227293
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Tnf
tumor necrosis factor
increases expression
ISO
graphene oxide results in increased expression of TNF mRNA
CTD
PMID:30549182 PMID:33227293
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Top1
DNA topoisomerase I
decreases expression
ISO
graphene oxide results in decreased expression of TOP1 protein
CTD
PMID:33219560
NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623
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Tp53
tumor protein p53
decreases expression increases expression
ISO
graphene oxide results in decreased expression of TP53 protein graphene oxide results in increased expression of TP53 mRNA
CTD
PMID:33219560 PMID:33219585
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpm2
tropomyosin 2
decreases expression
ISO
graphene oxide analog results in decreased expression of TPM2 mRNA
CTD
PMID:33227293
NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992
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Tra2a
transformer 2 alpha
decreases expression
ISO
graphene oxide results in decreased expression of TRA2A protein
CTD
PMID:33219560
NCBI chr 4:78,220,838...78,239,737
Ensembl chr 4:78,220,883...78,239,712
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Treh
trehalase
increases expression
ISO
graphene oxide results in increased expression of TREH mRNA
CTD
PMID:33227293
NCBI chr 8:44,990,182...45,003,881
Ensembl chr 8:44,990,182...45,003,540
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Tsku
tsukushi, small leucine rich proteoglycan
increases expression
ISO
graphene oxide results in increased expression of TSKU protein
CTD
PMID:33219560 PMID:33219576
NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
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Tubb2a
tubulin, beta 2A class IIa
decreases expression
ISO
graphene oxide analog results in decreased expression of TUBB2A mRNA
CTD
PMID:33227293
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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Ubc
ubiquitin C
decreases expression
ISO
graphene oxide results in decreased expression of UBC mRNA
CTD
PMID:33227293
NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
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Usp2
ubiquitin specific peptidase 2
increases expression
ISO
graphene oxide results in increased expression of USP2 mRNA
CTD
PMID:33227293
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Wdr49
WD repeat domain 49
increases expression
ISO
graphene oxide results in increased expression of WDR49 mRNA
CTD
PMID:29348435
NCBI chr 2:160,049,478...160,264,581
Ensembl chr 2:160,051,458...160,264,511
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Xbp1
X-box binding protein 1
multiple interactions
ISO
graphene oxide results in increased expression of and results in increased splicing of XBP1 mRNA
CTD
PMID:33973267
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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