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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:anilide
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Accession:CHEBI:13248 term browser browse the term
Definition:Any aromatic amide obtained by acylation of aniline.
Synonyms:related_synonym: Formula=C7H6NOR;   N-phenyl amide;   N-phenyl amides;   SMILES=[*]C(=O)Nc1ccccc1;   an anilide
 xref: KEGG:C01402;   PMID:23535982;   PMID:23968552;   PMID:24273122;   PMID:6205897


show annotations for term's descendants           Sort by:
3,3',4',5-tetrachlorosalicylanilide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO 3,3',4',5-tetrachlorosalicylanilide results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 3,3',4',5-tetrachlorosalicylanilide results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO 3,3',4',5-tetrachlorosalicylanilide inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO 3,3',4',5-tetrachlorosalicylanilide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
acetochlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity
multiple interactions		 ISO acetochlor results in increased activity of ABCB1 protein
ABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]		 CTD PMID:18433974 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases export ISO ABCC1 protein results in increased export of acetochlor metabolite CTD PMID:18433974 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Aplf aprataxin and PNKP like factor affects response to substance ISO APLF gene SNP affects the susceptibility to acetochlor CTD PMID:25622337 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Ar androgen receptor multiple interactions ISO acetochlor inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO acetochlor results in increased expression of BAD protein CTD PMID:25291404 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO acetochlor results in increased expression of BAK1 protein CTD PMID:25291404 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO acetochlor results in increased expression of BAX protein CTD PMID:25291404 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2l1 Bcl2-like 1 affects expression ISO acetochlor affects the expression of BCL2L1 protein CTD PMID:25291404 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO acetochlor results in increased expression of BID protein CTD PMID:25291404 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased expression of CASP3 protein modified form] CTD PMID:25291404 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of CASP9 protein] CTD PMID:25291404 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of acetochlor CTD PMID:11133395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of acetochlor CTD PMID:11133395 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO acetochlor binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO acetochlor binds to and results in decreased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Gfral GDNF family receptor alpha like affects response to substance ISO GFRAL gene SNP affects the susceptibility to acetochlor CTD PMID:25622337 NCBI chr 8:76,917,894...76,963,258
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased phosphorylation of MAPK1 protein] CTD PMID:25291404 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO acetochlor results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased phosphorylation of MAPK3 protein]		 CTD PMID:25291404 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO acetochlor affects the expression of MCL1 protein CTD PMID:25291404 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Msl1 MSL complex subunit 1 multiple interactions ISO [Herbicides results in increased abundance of acetochlor] which affects the methylation of MSL1 gene CTD PMID:34516295 NCBI chr10:83,755,380...83,767,147
Ensembl chr10:83,755,720...83,765,726 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO acetochlor binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of PARP1 protein] CTD PMID:25291404 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO acetochlor binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 multiple interactions ISO [Herbicides results in increased abundance of acetochlor] which affects the methylation of QSOX1 gene CTD PMID:34516295 NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459 		JBrowse link
G Rimklb ribosomal modification protein rimK-like family member B affects response to substance ISO RIMKLB gene SNP affects the susceptibility to acetochlor CTD PMID:25622337 NCBI chr 4:155,664,392...155,706,888
Ensembl chr 4:155,664,375...155,706,711 		JBrowse link
G Rnf126 ring finger protein 126 multiple interactions ISO [Herbicides results in increased abundance of acetochlor] which affects the methylation of RNF126 gene CTD PMID:34516295 NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738 		JBrowse link
G Rrp9 ribosomal RNA processing 9, U3 small nucleolar RNA binding protein multiple interactions ISO [Herbicides results in increased abundance of acetochlor] which affects the methylation of RRP9 gene CTD PMID:34516295 NCBI chr 8:107,116,411...107,126,123
Ensembl chr 8:107,117,471...107,126,123 		JBrowse link
G Thrb thyroid hormone receptor beta affects binding
multiple interactions		 ISO acetochlor binds to THRB protein
acetochlor binds to and results in decreased activity of THRB protein		 CTD PMID:28973306 PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Ttc7b tetratricopeptide repeat domain 7B multiple interactions ISO [Herbicides results in increased abundance of acetochlor] which affects the methylation of TTC7B gene CTD PMID:34516295 NCBI chr 6:119,587,389...119,799,167
Ensembl chr 6:119,587,390...119,799,330 		JBrowse link
alachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases activity		 ISO ABCB1 protein affects the reaction [alachlor results in increased susceptibility to Paclitaxel]
alachlor results in increased activity of ABCB1 protein		 CTD PMID:18433974 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ache acetylcholinesterase increases activity
increases expression		 ISO
EXP		 alachlor results in increased activity of ACHE protein
alachlor results in increased expression of ACHE mRNA		 CTD PMID:12419858 PMID:16998629 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acsm4 acyl-CoA synthetase medium-chain family member 4 affects expression EXP alachlor affects the expression of ACSM4 mRNA CTD PMID:19425180 NCBI chr 1:174,053,931...174,078,345
Ensembl chr 1:174,053,931...174,078,341 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression EXP alachlor results in increased expression of ADARB1 mRNA CTD PMID:12419858 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide affects expression EXP alachlor affects the expression of ADH7 mRNA CTD PMID:19425180 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Aen apoptosis enhancing nuclease affects expression EXP alachlor affects the expression of AEN mRNA CTD PMID:19425180 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 increases expression EXP alachlor results in increased expression of AGO2 mRNA CTD PMID:12419858 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Apod apolipoprotein D affects expression EXP alachlor affects the expression of APOD mRNA CTD PMID:19425180 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Ar androgen receptor multiple interactions ISO alachlor inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [alachlor results in increased activity of AR protein] CTD PMID:15064155 PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 affects expression EXP alachlor affects the expression of ARHGAP35 mRNA CTD PMID:19425180 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP alachlor results in increased expression of ATIC mRNA CTD PMID:12419858 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP alachlor results in increased expression of BAX mRNA CTD PMID:12419858 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases response to substance		 ISO alachlor results in increased expression of BCL2 protein
fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to alachlor]		 CTD PMID:10545406 PMID:12730627 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bin1 bridging integrator 1 increases expression EXP alachlor results in increased expression of BIN1 mRNA CTD PMID:12419858 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression EXP alachlor results in increased expression of CALCA mRNA CTD PMID:12419858 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP alachlor results in increased expression of CA2 mRNA CTD PMID:12419858 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Ccnb1 cyclin B1 increases expression EXP alachlor results in increased expression of CCNB1 mRNA CTD PMID:12419858 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein CTD PMID:19883720 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP alachlor results in increased expression of CCND2 mRNA CTD PMID:12419858 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd200 Cd200 molecule increases expression EXP alachlor results in increased expression of CD200 mRNA CTD PMID:12419858 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cdc123 cell division cycle 123 increases expression EXP alachlor results in increased expression of CDC123 mRNA CTD PMID:12419858 NCBI chr17:72,459,270...72,503,316
Ensembl chr17:72,459,282...72,503,316 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP alachlor results in increased expression of CDK1 mRNA CTD PMID:12419858 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Ces5a carboxylesterase 5A affects expression EXP alachlor affects the expression of CES5A mRNA CTD PMID:19425180 NCBI chr19:11,469,431...11,499,007
Ensembl chr19:11,469,469...11,499,006 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP alachlor results in increased expression of CGREF1 mRNA CTD PMID:12419858 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression EXP alachlor results in increased expression of CLIP2 mRNA CTD PMID:12419858 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression EXP alachlor results in increased expression of COL11A1 mRNA CTD PMID:12419858 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP alachlor results in increased expression of COL5A1 mRNA CTD PMID:12419858 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP alachlor results in increased expression of COL5A2 mRNA CTD PMID:12419858 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Cplx2 complexin 2 increases expression EXP alachlor results in increased expression of CPLX2 mRNA CTD PMID:12419858 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855 		JBrowse link
G Cpz carboxypeptidase Z increases expression EXP alachlor results in increased expression of CPZ mRNA CTD PMID:12419858 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression EXP alachlor results in increased expression of CRABP2 mRNA CTD PMID:12419858 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP alachlor results in increased expression of CXCR4 mRNA CTD PMID:12419858 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP alachlor results in increased expression of CYP1A1 protein CTD PMID:11850968 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP1A2 protein CTD PMID:11850968 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression EXP alachlor results in decreased expression of CYP2A3 protein CTD PMID:16698726 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP alachlor results in increased expression of and results in increased activity of CYP2B1 protein CTD PMID:11850968 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP alachlor results in increased expression of CYP2B2 protein CTD PMID:11850968 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases response to substance ISO CYP2B6 protein results in decreased susceptibility to alachlor CTD PMID:16277416 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
increases expression
multiple interactions		 ISO CYP3A4 protein results in increased metabolism of alachlor
alachlor results in increased expression of CYP3A4 mRNA
[CYP3A4 protein results in increased metabolism of alachlor] which results in increased abundance of 2-chloro-N-(2,6-diethylphenyl)acetamide		 CTD PMID:10475613 PMID:16565514 PMID:18273908 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP alachlor results in increased expression of CYP3A23-3A1 mRNA CTD PMID:14613717 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Defa5 defensin alpha 5 increases expression EXP alachlor results in increased expression of DEFA5 mRNA CTD PMID:12419858 NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP alachlor results in increased expression of DMBT1 mRNA CTD PMID:12419858 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP alachlor results in increased expression of EIF4EBP1 mRNA CTD PMID:12419858 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eln elastin increases expression EXP alachlor results in increased expression of ELN mRNA CTD PMID:12419858 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP alachlor results in increased expression of ENTPD2 mRNA CTD PMID:12419858 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP alachlor results in increased expression of ERP29 mRNA CTD PMID:12419858 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions		 ISO alachlor binds to ESR1 protein
[Dieldrin co-treated with alachlor] inhibits the reaction [Estradiol binds to ESR1 protein]; alachlor inhibits the reaction [Estradiol binds to ESR1 protein]		 CTD PMID:9168004 PMID:14579009 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression EXP alachlor results in increased expression of FDPS mRNA CTD PMID:12419858 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fntb farnesyltransferase, CAAX box, subunit beta increases expression EXP alachlor results in increased expression of FNTB mRNA CTD PMID:12419858 NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586 		JBrowse link
G Foxa2 forkhead box A2 increases expression EXP alachlor results in increased expression of FOXA2 mRNA CTD PMID:12419858 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression EXP alachlor results in increased expression of FYN mRNA CTD PMID:12419858 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP alachlor results in increased expression of GADD45A mRNA CTD PMID:12419858 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP alachlor results in increased expression of GCLC protein CTD PMID:14563481 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP alachlor results in increased expression of GCLM protein CTD PMID:14563481 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gk glycerol kinase affects expression EXP alachlor affects the expression of GK mRNA CTD PMID:19425180 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631 		JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP alachlor results in increased expression of GNG8 mRNA CTD PMID:12419858 NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371 		JBrowse link
G Gpx6 glutathione peroxidase 6 increases expression EXP alachlor results in increased expression of GPX6 mRNA CTD PMID:12419858 NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hbb hemoglobin subunit beta affects binding EXP alachlor binds to HBB protein CTD PMID:10075819 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hdc histidine decarboxylase increases expression EXP alachlor results in increased expression of HDC mRNA CTD PMID:12419858 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP alachlor results in increased expression of HMGB2 mRNA CTD PMID:12419858 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP alachlor results in increased expression of HMOX1 mRNA CTD PMID:12419858 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP alachlor results in increased expression of HNRNPA1 mRNA CTD PMID:12419858 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Homer2 homer scaffold protein 2 increases expression EXP alachlor results in increased expression of HOMER2 mRNA CTD PMID:12419858 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP alachlor results in increased expression of HSP90AA1 mRNA alternative form CTD PMID:8792849 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein] CTD PMID:15907790 PMID:18177342 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain affects expression EXP alachlor affects the expression of IGG-2A mRNA CTD PMID:19425180
G Jchain joining chain of multimeric IgA and IgM affects expression EXP alachlor affects the expression of JCHAIN mRNA CTD PMID:19425180 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Kif3b kinesin family member 3B affects expression EXP alachlor affects the expression of KIF3B mRNA CTD PMID:19425180 NCBI chr 3:141,758,466...141,798,012
Ensembl chr 3:141,758,466...141,797,963 		JBrowse link
G Klf6 KLF transcription factor 6 increases expression EXP alachlor results in increased expression of KLF6 mRNA CTD PMID:12419858 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Lgals1 galectin 1 increases expression EXP alachlor results in increased expression of LGALS1 mRNA CTD PMID:12419858 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 affects expression EXP alachlor affects the expression of LGI4 mRNA CTD PMID:19425180 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874 		JBrowse link
G Lxn latexin increases expression EXP alachlor results in increased expression of LXN mRNA CTD PMID:12419858 NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP alachlor results in increased expression of MAP3K1 mRNA CTD PMID:12419858 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP alachlor results in increased expression of MARCKS mRNA CTD PMID:12419858 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP alachlor results in increased expression of MCM6 mRNA CTD PMID:12419858 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression EXP alachlor results in increased expression of MGAT2 mRNA CTD PMID:12419858 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
increases activity		 EXP alachlor results in increased expression of MMP2 mRNA
alachlor results in increased activity of MMP2 protein		 CTD PMID:12419858 PMID:16178123 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression EXP alachlor results in increased expression of MMP9 mRNA CTD PMID:12419858 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 affects expression EXP alachlor affects the expression of MOXD2 mRNA CTD PMID:19425180 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Mt3 metallothionein 3 increases expression EXP alachlor results in increased expression of MT3 mRNA CTD PMID:12419858 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP alachlor results in increased expression of MVD mRNA CTD PMID:12419858 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein CTD PMID:19883720 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO alachlor results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; alachlor inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:15907790 PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:15907790 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:15907790 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alachlor inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:15907790 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions		 ISO
EXP		 alachlor results in increased activity of NR1I2 protein
alachlor binds to and results in increased activity of NR1I2 protein		 CTD PMID:14613717 PMID:16565514 PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO alachlor results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO alachlor inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; alachlor inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Obp2b odorant binding protein 2B increases expression EXP alachlor results in increased expression of OBP2B mRNA CTD PMID:12419858 NCBI chr 3:8,582,074...8,585,258
Ensembl chr 3:8,582,074...8,585,258 		JBrowse link
G Or7g31 olfactory receptor family 7 subfamily G member 31 affects expression EXP alachlor affects the expression of OR7G2 mRNA CTD PMID:19425180 NCBI chr 8:17,056,179...17,057,117
Ensembl chr 8:17,053,661...17,057,239 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer increases expression EXP alachlor results in increased expression of PCOLCE mRNA CTD PMID:12419858 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 increases expression EXP alachlor results in increased expression of PCSK6 mRNA CTD PMID:12419858 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP alachlor results in increased expression of PDK2 mRNA CTD PMID:12419858 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pgr progesterone receptor multiple interactions
affects binding		 ISO alachlor inhibits the reaction [Progesterone binds to PGR protein]
alachlor binds to PGR protein		 CTD PMID:14579009 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked increases expression EXP alachlor results in increased expression of PHEX mRNA CTD PMID:12419858 NCBI chr  X:37,607,553...37,856,183
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Plp1 proteolipid protein 1 affects expression EXP alachlor affects the expression of PLP1 mRNA CTD PMID:19425180 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Polr3g RNA polymerase III subunit G affects expression EXP alachlor affects the expression of POLR3G mRNA CTD PMID:19425180 NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125 		JBrowse link
G Prph peripherin increases expression EXP alachlor results in increased expression of PRPH mRNA CTD PMID:12419858 NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136 		JBrowse link
G Ptgds prostaglandin D2 synthase affects expression EXP alachlor affects the expression of PTGDS mRNA CTD PMID:19425180 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP alachlor results in increased expression of PTGR1 mRNA CTD PMID:12419858 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Qdpr quinoid dihydropteridine reductase increases expression EXP alachlor results in increased expression of QDPR mRNA CTD PMID:12419858 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase affects expression EXP alachlor affects the expression of QPRT mRNA CTD PMID:19425180 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
G Rassf8 Ras association domain family member 8 affects expression EXP alachlor affects the expression of RASSF8 mRNA CTD PMID:19425180 NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO alachlor inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:15907790 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rnf138 ring finger protein 138 affects expression EXP alachlor affects the expression of RNF138 mRNA CTD PMID:19425180 NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930 		JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression EXP alachlor results in increased expression of HLA-DMA mRNA CTD PMID:12419858 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP alachlor results in increased expression of S100A8 mRNA CTD PMID:12419858 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP alachlor results in increased expression of S100A9 mRNA CTD PMID:12419858 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scrg1 stimulator of chondrogenesis 1 affects expression EXP alachlor affects the expression of SCRG1 mRNA CTD PMID:19425180 NCBI chr16:32,760,028...32,788,299
Ensembl chr16:32,760,028...32,788,299 		JBrowse link
G Sec24c SEC24 homolog C, COPII coat complex component affects expression EXP alachlor affects the expression of SEC24C mRNA CTD PMID:19425180 NCBI chr15:3,602,460...3,624,524
Ensembl chr15:3,602,460...3,624,422 		JBrowse link
G Serpinb11 serpin family B member 11 affects expression EXP alachlor affects the expression of SERPINB11 mRNA CTD PMID:19425180 NCBI chr13:23,304,775...23,344,604
Ensembl chr13:23,304,456...23,344,604 		JBrowse link
G Serpinh1 serpin family H member 1 increases expression EXP alachlor results in increased expression of SERPINH1 mRNA CTD PMID:12419858 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression EXP alachlor results in increased expression of SLC16A1 mRNA CTD PMID:12419858 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc22a20 solute carrier family 22 member 20 affects expression EXP alachlor affects the expression of SLC22A20 mRNA CTD PMID:19425180 NCBI chr 1:203,257,374...203,273,854
Ensembl chr 1:203,257,374...203,273,822 		JBrowse link
G Slc25a35 solute carrier family 25, member 35 affects expression EXP alachlor affects the expression of SLC25A35 mRNA CTD PMID:19425180 NCBI chr10:53,672,851...53,677,501
Ensembl chr10:53,673,340...53,698,160 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression EXP alachlor results in increased expression of SLC4A2 mRNA CTD PMID:12419858 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Slc6a13 solute carrier family 6 member 13 affects expression EXP alachlor affects the expression of SLC6A13 mRNA CTD PMID:19425180 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression EXP alachlor results in increased expression of SLC7A1 mRNA CTD PMID:12419858 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N affects expression EXP alachlor affects the expression of SNRPN mRNA CTD PMID:19425180 NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:111,101,329...111,123,634 		JBrowse link
G Snurf SNRPN upstream open reading frame affects expression EXP alachlor affects the expression of SNURF mRNA CTD PMID:19425180 NCBI chr 1:111,101,327...111,123,634
Ensembl chr 1:111,101,329...111,123,634 		JBrowse link
G Sox11 SRY-box transcription factor 11 increases expression EXP alachlor results in increased expression of SOX11 mRNA CTD PMID:12419858 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked increases expression EXP alachlor results in increased expression of SRPX mRNA CTD PMID:12419858 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Tfrc transferrin receptor increases expression EXP alachlor results in increased expression of TFRC mRNA CTD PMID:12419858 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP alachlor results in increased expression of TIMP1 mRNA CTD PMID:12419858 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnc tenascin C increases expression EXP alachlor results in increased expression of TNC mRNA CTD PMID:12419858 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alachlor promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:15256756 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP alachlor results in increased expression of TOP2A mRNA CTD PMID:12419858 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP alachlor results in increased expression of TSHB protein CTD PMID:8812207 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
Anilofos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [anilofos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO anilofos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
butachlor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression ISO butachlor results in increased expression of ALB protein CTD PMID:34351278 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO butachlor results in decreased expression of APAF1 mRNA CTD PMID:34351278 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Ar androgen receptor increases activity ISO butachlor results in increased activity of AR protein CTD PMID:20143881 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atg5 autophagy related 5 decreases expression
increases expression		 ISO butachlor results in decreased expression of ATG5 mRNA
butachlor results in increased expression of ATG5 protein		 CTD PMID:34351278 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Casp3 caspase 3 decreases expression ISO butachlor results in decreased expression of CASP3 mRNA CTD PMID:34351278 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 decreases expression ISO butachlor results in decreased expression of CASP9 mRNA CTD PMID:34351278 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO butachlor results in decreased expression of CYCS mRNA CTD PMID:34351278 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of butachlor CTD PMID:11133395 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of butachlor CTD PMID:11133395 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO butachlor results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Il10 interleukin 10 decreases expression ISO butachlor results in decreased expression of IL10 mRNA CTD PMID:34351278 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO butachlor results in increased expression of MAP1LC3B protein CTD PMID:34351278 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO butachlor results in decreased expression of MTOR mRNA CTD PMID:34351278 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity ISO butachlor results in increased activity of NR1H4 protein CTD PMID:20143881 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases activity ISO butachlor results in increased activity of NR3C1 protein CTD PMID:20143881 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO butachlor results in decreased expression of SQSTM1 mRNA; butachlor results in decreased expression of SQSTM1 protein CTD PMID:34351278 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO butachlor binds to THRB protein CTD PMID:28973306 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO butachlor results in decreased expression of TNF mRNA CTD PMID:34351278 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
carboxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 decreases expression ISO Carboxin results in decreased expression of ANXA2 mRNA CTD PMID:33512557 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Bbc3 Bcl-2 binding component 3 decreases expression ISO Carboxin results in decreased expression of BBC3 mRNA CTD PMID:33512557 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
fentanyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
increases response to substance		 ISO
EXP		 ABCB1 protein results in increased transport of Fentanyl
tariquidar inhibits the reaction [ABCB1 protein results in increased transport of Fentanyl]
ABCB1 protein results in increased susceptibility to Fentanyl		 CTD PMID:29669042 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Acan aggrecan decreases expression EXP Fentanyl results in decreased expression of ACAN mRNA CTD PMID:36032789 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 decreases expression EXP Fentanyl results in decreased expression of ADAMTS14 mRNA CTD PMID:36032789 NCBI chr20:29,143,029...29,219,846
Ensembl chr20:29,144,354...29,219,866 		JBrowse link
G Adamtsl3 ADAMTS-like 3 affects expression EXP Fentanyl affects the expression of ADAMTSL3 mRNA CTD PMID:36032789 NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986 		JBrowse link
G Akap5 A-kinase anchoring protein 5 increases expression EXP Fentanyl results in increased expression of AKAP5 mRNA CTD PMID:36032789 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578 		JBrowse link
G Apln apelin decreases expression EXP Fentanyl results in decreased expression of APLN mRNA CTD PMID:36032789 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Arrb2 arrestin, beta 2 affects localization
multiple interactions		 ISO
EXP		 Fentanyl affects the localization of ARRB2 protein
[Fentanyl binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein		 CTD PMID:27030709 PMID:35477798 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bdnf brain-derived neurotrophic factor affects expression EXP Fentanyl affects the expression of BDNF mRNA CTD PMID:36032789 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bgn biglycan affects expression EXP Fentanyl affects the expression of BGN mRNA CTD PMID:36032789 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression EXP Fentanyl results in increased expression of BIRC3 mRNA CTD PMID:36032789 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression EXP Fentanyl results in increased expression of BST2 mRNA CTD PMID:36032789 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
G C3 complement C3 increases expression EXP Fentanyl results in increased expression of C3 mRNA CTD PMID:36032789 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E affects expression EXP Fentanyl affects the expression of CACNA1E mRNA CTD PMID:36032789 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Naloxone inhibits the reaction [Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]] CTD PMID:27030709 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Cckbr cholecystokinin B receptor decreases expression EXP Fentanyl results in decreased expression of CCKBR mRNA CTD PMID:36032789 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Fentanyl results in increased expression of CCL2 mRNA CTD PMID:36032789 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression EXP Fentanyl results in increased expression of CCL20 mRNA CTD PMID:36032789 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Fentanyl results in increased expression of CCL7 mRNA CTD PMID:36032789 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Cfb complement factor B increases expression EXP Fentanyl results in increased expression of CFB mRNA CTD PMID:36032789 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression EXP Fentanyl results in increased expression of CHI3L1 mRNA CTD PMID:36032789 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Clstn2 calsyntenin 2 affects expression EXP Fentanyl affects the expression of CLSTN2 mRNA CTD PMID:36032789 NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731 		JBrowse link
G Cntf ciliary neurotrophic factor increases expression EXP Fentanyl results in increased expression of CNTF mRNA CTD PMID:36032789 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression EXP Fentanyl results in increased expression of COL15A1 mRNA CTD PMID:36032789 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col26a1 collagen type XXVI alpha 1 chain increases expression EXP Fentanyl results in increased expression of COL26A1 mRNA CTD PMID:36032789 NCBI chr12:19,792,693...19,938,556
Ensembl chr12:19,792,728...19,938,556 		JBrowse link
G Col3a1 collagen type III alpha 1 chain affects expression EXP Fentanyl affects the expression of COL3A1 mRNA CTD PMID:36032789 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Crh corticotropin releasing hormone affects expression
increases expression		 EXP Fentanyl affects the expression of CRH mRNA
Fentanyl results in increased expression of CRH mRNA		 CTD PMID:18819432 PMID:36032789 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 affects expression EXP Fentanyl affects the expression of CRLF1 mRNA CTD PMID:36032789 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997 		JBrowse link
G Csf1 colony stimulating factor 1 increases expression EXP Fentanyl results in increased expression of CSF1 mRNA CTD PMID:36032789 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Fentanyl results in increased expression of CXCL1 mRNA CTD PMID:36032789 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP Fentanyl results in increased expression of CXCL10 mRNA CTD PMID:36032789 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression EXP Fentanyl results in increased expression of CXCL11 mRNA CTD PMID:36032789 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP Fentanyl results in increased expression of CXCL12 mRNA CTD PMID:36032789 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression EXP Fentanyl results in increased expression of CXCL13 mRNA CTD PMID:36032789 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 increases expression EXP Fentanyl results in increased expression of CXCL16 mRNA CTD PMID:36032789 NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity ISO Fentanyl results in increased activity of CYP2B6 protein CTD PMID:35914676 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of Fentanyl CTD PMID:11811955 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dcn decorin increases expression EXP Fentanyl results in increased expression of DCN mRNA CTD PMID:36032789 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ednrb endothelin receptor type B decreases expression EXP Fentanyl results in decreased expression of EDNRB mRNA CTD PMID:36032789 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Fbln5 fibulin 5 decreases expression EXP Fentanyl results in decreased expression of FBLN5 mRNA CTD PMID:36032789 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression EXP Fentanyl results in increased expression of FGR mRNA CTD PMID:36032789 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Fentanyl results in increased expression of FOS protein CTD PMID:7970238 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gast gastrin multiple interactions EXP [fluanisone co-treated with Fentanyl co-treated with Midazolam] inhibits the reaction [GAST protein results in increased secretion of Histamine] CTD PMID:10864877 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression EXP Fentanyl results in increased expression of GBP2 mRNA CTD PMID:36032789 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist decreases expression EXP Fentanyl results in decreased expression of GREM1 mRNA CTD PMID:36032789 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A affects expression EXP Fentanyl affects the expression of GRIN2A mRNA CTD PMID:36032789 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B affects expression EXP Fentanyl affects the expression of GRIN2B mRNA CTD PMID:36032789 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 affects expression EXP Fentanyl affects the expression of GRM1 mRNA CTD PMID:36032789 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm3 glutamate metabotropic receptor 3 affects expression EXP Fentanyl affects the expression of GRM3 mRNA CTD PMID:36032789 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804 		JBrowse link
G Has1 hyaluronan synthase 1 decreases expression EXP Fentanyl results in decreased expression of HAS1 mRNA CTD PMID:36032789 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397 		JBrowse link
G Hcrtr1 hypocretin receptor 1 decreases expression EXP Fentanyl results in decreased expression of HCRTR1 mRNA CTD PMID:36032789 NCBI chr 5:142,477,214...142,486,674
Ensembl chr 5:142,477,214...142,486,674 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects expression EXP Fentanyl affects the expression of HTR2A mRNA CTD PMID:36032789 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression EXP Fentanyl results in increased expression of IFIT3 mRNA CTD PMID:36032789 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Il1a interleukin 1 alpha increases expression EXP Fentanyl results in increased expression of IL1A mRNA CTD PMID:36032789 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il2 interleukin 2 decreases expression ISO Fentanyl results in decreased expression of IL2 mRNA CTD PMID:23965172 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 increases expression ISO Fentanyl results in increased expression of IL4 mRNA CTD PMID:23965172 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il7 interleukin 7 increases expression EXP Fentanyl results in increased expression of IL7 mRNA CTD PMID:36032789 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Irf7 interferon regulatory factor 7 increases expression EXP Fentanyl results in increased expression of IRF7 mRNA CTD PMID:36032789 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression EXP Fentanyl results in increased expression of ISG15 mRNA CTD PMID:36032789 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itga11 integrin subunit alpha 11 increases expression EXP Fentanyl results in increased expression of ITGA11 mRNA CTD PMID:36032789 NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407 		JBrowse link
G Itgal integrin subunit alpha L increases expression EXP Fentanyl results in increased expression of ITGAL mRNA CTD PMID:36032789 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Fentanyl results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lamb3 laminin subunit beta 3 decreases expression EXP Fentanyl results in decreased expression of LAMB3 mRNA CTD PMID:36032789 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lamc2 laminin subunit gamma 2 affects expression EXP Fentanyl affects the expression of LAMC2 mRNA CTD PMID:36032789 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lcn2 lipocalin 2 increases expression EXP Fentanyl results in increased expression of LCN2 mRNA CTD PMID:36032789 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lox lysyl oxidase decreases expression EXP Fentanyl results in decreased expression of LOX mRNA CTD PMID:36032789 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Loxl1 lysyl oxidase-like 1 increases expression EXP Fentanyl results in increased expression of LOXL1 mRNA CTD PMID:36032789 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356 		JBrowse link
G Loxl2 lysyl oxidase-like 2 decreases expression EXP Fentanyl results in decreased expression of LOXL2 mRNA CTD PMID:36032789 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Ltb lymphotoxin beta increases expression EXP Fentanyl results in increased expression of LTB mRNA CTD PMID:36032789 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Fentanyl results in increased phosphorylation of MAPK1 protein CTD PMID:23965172 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Fentanyl results in increased phosphorylation of MAPK3 protein CTD PMID:23965172 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Fentanyl results in decreased expression of MAS1 mRNA CTD PMID:36032789 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression EXP Fentanyl results in increased expression of MMP2 mRNA CTD PMID:36032789 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP Fentanyl results in decreased expression of MMP9 mRNA CTD PMID:36032789 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mx1 MX dynamin like GTPase 1 increases expression EXP Fentanyl results in increased expression of MX1 mRNA CTD PMID:36032789 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507 		JBrowse link
G Mx2 MX dynamin like GTPase 2 increases expression EXP Fentanyl results in increased expression of MX2 mRNA CTD PMID:36032789 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO
EXP		 Fentanyl results in increased expression of NFKBIA protein
Fentanyl results in increased expression of NFKBIA mRNA		 CTD PMID:22258905 PMID:36032789 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nid2 nidogen 2 decreases expression EXP Fentanyl results in decreased expression of NID2 mRNA CTD PMID:36032789 NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843 		JBrowse link
G Nppc natriuretic peptide C affects expression EXP Fentanyl affects the expression of NPPC mRNA CTD PMID:36032789 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Nts neurotensin decreases expression EXP Fentanyl results in decreased expression of NTS mRNA CTD PMID:36032789 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP Fentanyl results in increased expression of OASL mRNA CTD PMID:36032789 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Oprd1 opioid receptor, delta 1 affects binding EXP Fentanyl binds to OPRD1 protein CTD PMID:35477798 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 affects binding EXP Fentanyl binds to OPRK1 protein CTD PMID:35477798 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 increases phosphorylation
multiple interactions		 ISO
EXP		 Fentanyl results in increased phosphorylation of OPRM1 protein
[Fentanyl binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; Fentanyl binds to and results in increased activity of OPRM1 protein		 CTD PMID:17240843 PMID:21957251 PMID:23300227 PMID:35477798 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression EXP Fentanyl results in decreased expression of P4HA2 mRNA CTD PMID:36032789 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314 		JBrowse link
G Pdyn prodynorphin increases expression EXP Fentanyl results in increased expression of PDYN protein CTD PMID:19200067 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pf4 platelet factor 4 increases expression EXP Fentanyl results in increased expression of PF4 mRNA CTD PMID:36032789 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pld2 phospholipase D2 increases activity ISO Fentanyl results in increased activity of PLD2 protein CTD PMID:23965172 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Pomc proopiomelanocortin decreases expression
multiple interactions		 ISO Fentanyl results in decreased expression of POMC protein alternative form
[Fentanyl co-treated with Morphine] results in decreased expression of POMC protein alternative form		 CTD PMID:20084599 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prlhr prolactin releasing hormone receptor decreases expression EXP Fentanyl results in decreased expression of PRLHR mRNA CTD PMID:36032789 NCBI chr 1:259,606,704...259,608,391
Ensembl chr 1:259,606,704...259,608,391 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP Fentanyl results in increased expression of PSMB9 mRNA CTD PMID:36032789 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Pthlh parathyroid hormone-like hormone affects expression EXP Fentanyl affects the expression of PTHLH mRNA CTD PMID:36032789 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptx3 pentraxin 3 increases expression EXP Fentanyl results in increased expression of PTX3 mRNA CTD PMID:36032789 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Reln reelin increases expression EXP Fentanyl results in increased expression of RELN mRNA CTD PMID:36032789 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Ren renin multiple interactions ISO [Fentanyl co-treated with Isoflurane] results in decreased expression of REN protein CTD PMID:3284271 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Fentanyl results in increased expression of S100A8 mRNA CTD PMID:36032789 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G Scg2 secretogranin II affects expression EXP Fentanyl affects the expression of SCG2 mRNA CTD PMID:36032789 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Sema3a semaphorin 3A decreases expression EXP Fentanyl results in decreased expression of SEMA3A mRNA CTD PMID:36032789 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression EXP Fentanyl results in increased expression of SLC11A1 mRNA CTD PMID:36032789 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 affects expression EXP Fentanyl affects the expression of SLC8A2 mRNA CTD PMID:36032789 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP Fentanyl results in increased expression of SOD2 mRNA CTD PMID:36032789 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sorcs3 sortilin-related VPS10 domain containing receptor 3 decreases expression EXP Fentanyl results in decreased expression of SORCS3 mRNA CTD PMID:36032789 NCBI chr 1:247,099,178...247,734,027
Ensembl chr 1:247,099,408...247,734,027 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression EXP Fentanyl affects the expression of SPP1 mRNA CTD PMID:36032789 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression EXP Fentanyl results in increased expression of TLR2 mRNA CTD PMID:36032789 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression EXP Fentanyl results in increased expression of TNFRSF9 mRNA CTD PMID:36032789 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Fentanyl results in increased expression of VCAM1 mRNA CTD PMID:36032789 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP Fentanyl results in decreased expression of VEGFA mRNA CTD PMID:36032789 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vgf VGF nerve growth factor inducible affects expression EXP Fentanyl affects the expression of VGF mRNA CTD PMID:36032789 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Wnt10a Wnt family member 10A affects expression EXP Fentanyl affects the expression of WNT10A mRNA CTD PMID:36032789 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
hydroxyflutamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of ADAMTS1 mRNA]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of ADAMTS1 protein] CTD PMID:17018655 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 EXP hydroxyflutamide results in increased phosphorylation of AKT1 protein
hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [hydroxyflutamide results in increased phosphorylation of AKT1 protein]		 CTD PMID:26437446 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ar androgen receptor decreases activity
decreases phosphorylation
increases response to substance
multiple interactions
affects activity
affects binding		 ISO
EXP		 hydroxyflutamide results in decreased activity of AR protein
hydroxyflutamide results in decreased phosphorylation of AR protein
AR protein mutant form results in increased susceptibility to hydroxyflutamide
[AR protein mutant form results in increased susceptibility to hydroxyflutamide] which results in increased activity of AR protein mutant form; hydroxyflutamide binds to and results in decreased activity of AR protein; hydroxyflutamide binds to and results in increased activity of AR protein; hydroxyflutamide binds to and results in increased activity of AR protein mutant form; hydroxyflutamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of AR mRNA]; hydroxyflutamide inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of AR protein]; hydroxyflutamide inhibits the reaction [Cadmium Chloride binds to AR protein]; hydroxyflutamide inhibits the reaction [Cadmium Chloride results in decreased expression of AR mRNA]; hydroxyflutamide inhibits the reaction [Cadmium Chloride results in decreased expression of AR protein]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Estradiol results in decreased expression of AR protein]]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; hydroxyflutamide inhibits the reaction [Metribolone results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Testosterone results in increased phosphorylation of AR protein]; OSM protein promotes the reaction [hydroxyflutamide binds to and results in increased activity of AR protein]
hydroxyflutamide affects the activity of AR protein
hydroxyflutamide inhibits the reaction [Metribolone binds to AR protein]
hydroxyflutamide analog binds to AR protein; hydroxyflutamide binds to AR protein
hydroxyflutamide binds to and results in decreased activity of AR protein; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of AR mRNA]		 CTD PMID:10053169 PMID:11751618 PMID:11861974 PMID:11861975 PMID:12114440 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Avp arginine vasopressin affects expression EXP hydroxyflutamide affects the expression of AVP mRNA CTD PMID:20810896 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Cdh1 cadherin 1 increases phosphorylation
multiple interactions		 ISO hydroxyflutamide results in increased phosphorylation of CDH1 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [hydroxyflutamide results in increased phosphorylation of CDH1 protein]		 CTD PMID:28163245 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases phosphorylation		 ISO 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [hydroxyflutamide results in decreased phosphorylation of CDH2 protein]; wortmannin inhibits the reaction [hydroxyflutamide results in decreased phosphorylation of CDH2 protein] CTD PMID:28163245 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Ctnnb1 catenin beta 1 decreases phosphorylation
multiple interactions		 ISO hydroxyflutamide results in decreased phosphorylation of CTNNB1 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [hydroxyflutamide results in decreased phosphorylation of CTNNB1 protein]; wortmannin inhibits the reaction [hydroxyflutamide results in decreased phosphorylation of CTNNB1 protein]		 CTD PMID:28163245 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO hydroxyflutamide results in decreased expression of CYP11A1 mRNA CTD PMID:29556062 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO hydroxyflutamide results in increased expression of CYP17A1 mRNA CTD PMID:29556062 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO hydroxyflutamide binds to and results in increased activity of ESR1 protein; hydroxyflutamide inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of ESR1 protein] CTD PMID:18275596 PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [Testosterone co-treated with hydroxyflutamide] results in decreased expression of GJA1 protein; hydroxyflutamide results in decreased expression of and affects the localization of GJA1 protein; wortmannin inhibits the reaction [hydroxyflutamide results in decreased expression of GJA1 protein] CTD PMID:26437446 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO hydroxyflutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [BCG Vaccine results in increased expression of IL6 mRNA]] CTD PMID:14532843 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 affects secretion
affects expression
decreases expression
increases secretion
multiple interactions		 ISO hydroxyflutamide affects the secretion of KLK3 protein
hydroxyflutamide affects the expression of KLK3 mRNA
hydroxyflutamide results in decreased expression of KLK3 mRNA
hydroxyflutamide results in increased secretion of KLK3 protein
hydroxyflutamide inhibits the reaction [1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane results in increased expression of KLK3 protein]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]; hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased secretion of KLK3 protein]		 CTD PMID:20363314 PMID:25454221 PMID:29556062 PMID:35595151 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 decreases expression ISO hydroxyflutamide results in decreased expression of LCP1 mRNA CTD PMID:29556062 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
affects phosphorylation
increases phosphorylation		 EXP
ISO		 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [hydroxyflutamide results in increased phosphorylation of MAPK1 protein]; hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]
hydroxyflutamide inhibits the reaction [Testosterone affects the phosphorylation of MAPK1 protein]
hydroxyflutamide affects the phosphorylation of MAPK1 protein		 CTD PMID:26437446 PMID:28163245 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
affects phosphorylation
multiple interactions		 EXP
ISO		 hydroxyflutamide results in increased phosphorylation of MAPK3 protein
hydroxyflutamide affects the phosphorylation of MAPK3 protein
hydroxyflutamide inhibits the reaction [Testosterone affects the phosphorylation of MAPK3 protein]
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [hydroxyflutamide results in increased phosphorylation of MAPK3 protein]; hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]		 CTD PMID:26437446 PMID:28163245 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Msmb microseminoprotein, beta decreases expression ISO hydroxyflutamide results in decreased expression of MSMB mRNA CTD PMID:29556062 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO hydroxyflutamide binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Osm oncostatin M multiple interactions ISO OSM protein promotes the reaction [hydroxyflutamide binds to and results in increased activity of AR protein] CTD PMID:12114440 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Pip prolactin induced protein multiple interactions
decreases expression		 ISO hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of PIP mRNA]
hydroxyflutamide results in decreased expression of PIP mRNA		 CTD PMID:10402478 NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO hydroxyflutamide binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Pten phosphatase and tensin homolog increases phosphorylation
multiple interactions		 EXP hydroxyflutamide results in increased phosphorylation of PTEN protein
hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of PTEN protein]		 CTD PMID:26437446 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
increases phosphorylation		 ISO wortmannin promotes the reaction [hydroxyflutamide results in increased phosphorylation of RAF1 protein] CTD PMID:28163245 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Sf1 splicing factor 1 decreases expression ISO hydroxyflutamide results in decreased expression of SF1 mRNA CTD PMID:29556062 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases phosphorylation
multiple interactions		 EXP hydroxyflutamide results in decreased phosphorylation of SRC protein
hydroxyflutamide inhibits the reaction [Testosterone results in increased phosphorylation of SRC protein]		 CTD PMID:26437446 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression ISO hydroxyflutamide results in decreased expression of SRD5A1 mRNA CTD PMID:29556062 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 multiple interactions ISO hydroxyflutamide inhibits the reaction [Dihydrotestosterone results in increased expression of SRD5A2 mRNA] CTD PMID:15056816 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO hydroxyflutamide binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO hydroxyflutamide binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
niclosamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein increases expression ISO Niclosamide results in increased expression of A1BG mRNA CTD PMID:36318118 NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 decreases expression ISO Niclosamide results in decreased expression of ABCA12 mRNA CTD PMID:36318118 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression ISO Niclosamide results in decreased expression of ABCC9 mRNA CTD PMID:36318118 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 increases expression ISO Niclosamide results in increased expression of ABCG4 mRNA CTD PMID:36318118 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Abhd1 abhydrolase domain containing 1 increases expression ISO Niclosamide results in increased expression of ABHD1 mRNA CTD PMID:36318118 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514 		JBrowse link
G Abhd14b abhydrolase domain containing 14b increases expression ISO Niclosamide results in increased expression of ABHD14B mRNA CTD PMID:36318118 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Niclosamide results in decreased expression of ACACA mRNA CTD PMID:22576131 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]		 CTD PMID:26792726 PMID:28824321 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Niclosamide results in decreased expression of ACSL1 mRNA CTD PMID:22576131 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of ACTA2 protein]
Niclosamide results in decreased expression of ACTA2 protein
Niclosamide results in decreased expression of ACTA2 mRNA; Niclosamide results in decreased expression of ACTA2 protein
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of ACTA2 protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of ACTA2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of ACTA2 protein]		 CTD PMID:26643609 PMID:28318631 PMID:34118929 PMID:35115509 PMID:36870549 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 decreases expression ISO Niclosamide results in decreased expression of ADAMTS17 mRNA CTD PMID:36318118 NCBI chr 1:120,445,800...120,768,204
Ensembl chr 1:120,445,749...120,768,202 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Niclosamide results in decreased expression of ADH4 mRNA CTD PMID:28284560 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adm2 adrenomedullin 2 increases expression ISO Niclosamide results in increased expression of ADM2 mRNA CTD PMID:36318118 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A decreases expression ISO Niclosamide results in decreased expression of ADRA2A mRNA CTD PMID:36318118 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]] CTD PMID:32961231 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agbl3 AGBL carboxypeptidase 3 decreases expression ISO Niclosamide results in decreased expression of AGBL3 mRNA CTD PMID:36318118 NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases cleavage ISO Niclosamide results in increased cleavage of AIFM1 protein CTD PMID:22576131 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Akna AT-hook transcription factor increases expression ISO Niclosamide results in increased expression of AKNA mRNA CTD PMID:36318118 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of AKT1 mRNA
Niclosamide inhibits the reaction [TNF protein results in increased activity of AKT1 protein]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:20215516 PMID:26792726 PMID:29843133 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO Niclosamide results in decreased expression of ALDH1A1 protein CTD PMID:24736023 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO Niclosamide results in increased expression of ALDH6A1 mRNA CTD PMID:36318118 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression ISO Niclosamide results in increased expression of ALDOB mRNA CTD PMID:22576131 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression
increases expression		 ISO Niclosamide results in decreased expression of ALDOC mRNA
Niclosamide results in increased expression of ALDOC mRNA		 CTD PMID:22576131 PMID:36318118 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alkbh7 alkB homolog 7 increases expression ISO Niclosamide results in increased expression of ALKBH7 mRNA CTD PMID:36318118 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression
multiple interactions
decreases response to substance		 ISO Niclosamide results in increased expression of ALOX12B mRNA
TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]
ALOX12B protein results in decreased susceptibility to Niclosamide		 CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases response to substance
increases expression		 ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]
ALOX5 protein results in decreased susceptibility to Niclosamide		 CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression ISO Niclosamide results in decreased expression of ALPL mRNA CTD PMID:28824321 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 increases expression ISO Niclosamide results in increased expression of AMHR2 mRNA CTD PMID:36318118 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258 		JBrowse link
G Amot angiomotin increases expression ISO Niclosamide results in increased expression of AMOT mRNA CTD PMID:36318118 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Ank3 ankyrin 3 increases expression ISO Niclosamide results in increased expression of ANK3 mRNA CTD PMID:36318118 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Ankmy2 ankyrin repeat and MYND domain containing 2 increases expression ISO Niclosamide results in increased expression of ANKMY2 mRNA CTD PMID:36318118 NCBI chr 6:52,888,959...52,930,343
Ensembl chr 6:52,888,963...52,930,394 		JBrowse link
G Ankrd12 ankyrin repeat domain 12 increases expression ISO Niclosamide results in increased expression of ANKRD12 mRNA CTD PMID:36318118 NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911 		JBrowse link
G Ankrd34a ankyrin repeat domain 34A increases expression ISO Niclosamide results in increased expression of ANKRD34A mRNA CTD PMID:36318118 NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116 		JBrowse link
G Anxa4 annexin A4 increases expression ISO Niclosamide results in increased expression of ANXA4 mRNA CTD PMID:36318118 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Niclosamide results in decreased expression of AP1S3 mRNA CTD PMID:36318118 NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798 		JBrowse link
G Aplnr apelin receptor decreases expression ISO Niclosamide results in decreased expression of APLNR mRNA CTD PMID:36318118 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Apof apolipoprotein F decreases expression ISO Niclosamide results in decreased expression of APOF mRNA CTD PMID:28284560 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression		 ISO [enzalutamide co-treated with Niclosamide] results in decreased expression of AR protein; [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]] which results in decreased expression of KLK3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form]; bicalutamide promotes the reaction [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]]; bicalutamide promotes the reaction [Niclosamide results in decreased expression of AR protein alternative form]; bicalutamide promotes the reaction [Niclosamide results in decreased expression of AR protein]; Niclosamide inhibits the reaction [AR protein alternative form binds to KLK3 promoter]; Niclosamide inhibits the reaction [AR protein alternative form results in decreased susceptibility to enzalutamide]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 mRNA]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]; Niclosamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form
Niclosamide results in decreased expression of AR protein; Niclosamide results in decreased expression of AR protein alternative form		 CTD PMID:24740322 PMID:25970160 PMID:28500234 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Niclosamide analog results in decreased expression of ARAF protein; Niclosamide results in decreased expression of ARAF protein CTD PMID:28284560 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Niclosamide results in increased expression of ARHGDIB mRNA CTD PMID:36318118 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 increases expression ISO Niclosamide results in increased expression of ARMCX1 mRNA CTD PMID:36318118 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299 		JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Niclosamide results in increased expression of ARRDC2 mRNA CTD PMID:36318118 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression ISO Niclosamide results in decreased expression of ASF1B mRNA CTD PMID:28284560 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Atcay ATCAY kinesin light chain interacting caytaxin increases expression ISO Niclosamide results in increased expression of ATCAY mRNA CTD PMID:36318118 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of ATF3 mRNA; Niclosamide results in increased expression of ATF3 protein
ATF3 protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; ATF3 protein affects the reaction [Niclosamide results in increased expression of DDIT3 mRNA]; ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA]		 CTD PMID:26917416 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Niclosamide results in increased expression of ATF4 mRNA; Niclosamide results in increased expression of ATF4 protein CTD PMID:26917416 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atosb atos homolog B increases expression ISO Niclosamide results in increased expression of ATOSB mRNA CTD PMID:36318118 NCBI chr 5:57,260,839...57,274,524
Ensembl chr 5:57,260,841...57,268,892 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Niclosamide results in increased expression of ATP2A3 mRNA CTD PMID:36318118 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression ISO Niclosamide results in increased expression of ATP5F1A mRNA CTD PMID:22576131 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression ISO Niclosamide results in increased expression of ATP5F1D mRNA CTD PMID:22576131 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Niclosamide results in decreased expression of ATP5MC3 mRNA CTD PMID:22576131 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279 		JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Niclosamide results in decreased expression of ATP5MF mRNA CTD PMID:22576131 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5mg ATP synthase membrane subunit G decreases expression ISO Niclosamide results in decreased expression of ATP5MG mRNA CTD PMID:22576131 NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b decreases expression ISO Niclosamide results in decreased expression of ATP5PB mRNA CTD PMID:22576131 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 decreases expression ISO Niclosamide results in decreased expression of ATP6AP1 mRNA CTD PMID:22576131 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA] CTD PMID:26792726 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase decreases expression ISO Niclosamide results in decreased expression of ATPSCKMT mRNA CTD PMID:36318118 NCBI chr 2:82,603,086...82,618,325
Ensembl chr 2:82,603,009...82,618,308 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Niclosamide results in decreased expression of AURKB mRNA CTD PMID:28284560 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Avpi1 arginine vasopressin-induced 1 increases expression ISO Niclosamide results in increased expression of AVPI1 mRNA CTD PMID:36318118 NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154 		JBrowse link
G Axin2 axin 2 multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
Niclosamide results in decreased expression of AXIN2 mRNA; Niclosamide results in decreased expression of AXIN2 protein		 CTD PMID:22576131 PMID:24534281 PMID:24552774 PMID:24736023 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 increases expression ISO Niclosamide results in increased expression of B3GNT7 mRNA CTD PMID:36318118 NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170 		JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 increases expression ISO Niclosamide results in increased expression of B3GNT9 mRNA CTD PMID:36318118 NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAD mRNA CTD PMID:25988281 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAK1 mRNA CTD PMID:25988281 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression		 ISO Niclosamide results in increased expression of BAX protein
[Niclosamide binds to Polyethyleneimine] which results in increased expression of BAX mRNA; [Niclosamide co-treated with bicalutamide] results in increased expression of BAX protein; bicalutamide inhibits the reaction [Niclosamide results in decreased expression of BAX protein]		 CTD PMID:25634333 PMID:25988281 PMID:26703449 PMID:28500234 PMID:35115509 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression		 ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of BBC3 mRNA] CTD PMID:30258081 PMID:36318118 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 increases expression ISO Niclosamide results in increased expression of BBS2 mRNA CTD PMID:36318118 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO Niclosamide analog results in decreased expression of BCL2 protein; Niclosamide results in decreased expression of BCL2 protein
[Niclosamide binds to Polyethyleneimine] which results in decreased expression of BCL2 mRNA; [Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; bicalutamide promotes the reaction [Niclosamide results in decreased expression of BCL2 protein]; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2 protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of BCL2 protein]		 CTD PMID:20215516 PMID:23894143 PMID:25634333 PMID:25988281 PMID:26116531 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression		 ISO [Niclosamide binds to Polyethyleneimine] which results in decreased expression of BCL2L1 mRNA; bicalutamide promotes the reaction [Niclosamide results in decreased expression of BCL2L1 protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of BCL2L1 protein]
Niclosamide analog results in decreased expression of BCL2L1 protein; Niclosamide results in decreased expression of BCL2L1 protein		 CTD PMID:20215516 PMID:25988281 PMID:26116531 PMID:28284560 PMID:28500234 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of BCL2L2 protein
[Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2L2 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2L2 protein]		 CTD PMID:23894143 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Niclosamide results in increased expression of BCL3 mRNA CTD PMID:36318118 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions
increases expression		 ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 protein]
Niclosamide results in increased expression of BCL6 mRNA		 CTD PMID:33632240 PMID:36318118 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression ISO Niclosamide results in increased expression of BCL6B mRNA CTD PMID:36318118 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974 		JBrowse link
G Bcl9 BCL9, transcription coactivator decreases expression EXP Niclosamide results in decreased expression of BCL9 mRNA CTD PMID:27338550 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435 		JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 increases expression ISO Niclosamide results in increased expression of BCORL1 mRNA CTD PMID:36318118 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087 		JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like increases expression ISO Niclosamide results in increased expression of BET1L mRNA CTD PMID:36318118 NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040 		JBrowse link
G Bgn biglycan increases expression ISO Niclosamide results in increased expression of BGN mRNA CTD PMID:36318118 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Niclosamide results in increased expression of BHLHE40 mRNA CTD PMID:36318118 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
affects expression
decreases expression		 ISO enzalutamide promotes the reaction [Niclosamide results in decreased expression of BIRC5 protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of BIRC5 protein]
Niclosamide affects the expression of BIRC5 protein
Niclosamide analog results in decreased expression of BIRC5 protein; Niclosamide results in decreased expression of BIRC5 mRNA; Niclosamide results in decreased expression of BIRC5 protein		 CTD PMID:24552774 PMID:24736023 PMID:25970160 PMID:28284560 PMID:28500234 More... NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Niclosamide results in increased expression of BMF mRNA CTD PMID:36318118 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Borcs6 BLOC-1 related complex subunit 6 increases expression ISO Niclosamide results in increased expression of BORCS6 mRNA CTD PMID:36318118 NCBI chr10:53,760,504...53,762,358
Ensembl chr10:53,758,093...53,762,632 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression
decreases phosphorylation		 ISO Niclosamide analog results in decreased expression of BRAF protein; Niclosamide results in decreased expression of BRAF protein
Niclosamide analog results in decreased phosphorylation of BRAF protein		 CTD PMID:28284560 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Btbd7 BTB domain containing 7 decreases expression ISO Niclosamide results in decreased expression of BTBD7 mRNA CTD PMID:36318118 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Niclosamide results in increased expression of BTG2 mRNA CTD PMID:36318118 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C13h1orf105 similar to human chromosome 1 open reading frame 105 decreases expression ISO Niclosamide results in decreased expression of C1ORF105 mRNA CTD PMID:36318118 NCBI chr13:74,313,320...74,356,322
Ensembl chr13:74,313,322...74,356,322 		JBrowse link
G C16h8orf48 similar to human chromosome 8 open reading frame 48 decreases expression ISO Niclosamide results in decreased expression of C8ORF48 mRNA CTD PMID:36318118 NCBI chr16:55,244,744...55,246,642
Ensembl chr16:55,236,322...55,246,650 		JBrowse link
G C19h16orf86 similar to human chromosome 16 open reading frame 86 increases expression ISO Niclosamide results in increased expression of C16ORF86 mRNA CTD PMID:36318118 NCBI chr19:33,596,591...33,598,703
Ensembl chr19:33,595,995...33,598,521 		JBrowse link
G C1ql4 complement C1q like 4 increases expression ISO Niclosamide results in increased expression of C1QL4 mRNA CTD PMID:36318118 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678 		JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Niclosamide results in decreased expression of CABLES2 mRNA CTD PMID:36318118 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:167,347,461...167,362,279 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression ISO Niclosamide results in increased expression of CACNA1E mRNA CTD PMID:36318118 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression ISO Niclosamide results in increased expression of CACNA1H mRNA CTD PMID:36318118 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 increases expression ISO Niclosamide results in increased expression of CACNG1 mRNA CTD PMID:36318118 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO Niclosamide results in increased expression of CAMK2A mRNA CTD PMID:36318118 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 increases expression ISO Niclosamide results in increased expression of CAMSAP3 mRNA CTD PMID:36318118 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685 		JBrowse link
G Caps calcyphosine increases expression ISO Niclosamide results in increased expression of CAPS mRNA CTD PMID:36318118 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Niclosamide co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASP1 protein
Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]		 CTD PMID:33524445 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
decreases expression		 ISO
EXP		 Niclosamide results in increased cleavage of CASP3 protein
Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]]
[TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased expression of CASP3 protein modified form; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]
Niclosamide results in increased expression of CASP3 protein modified form
Niclosamide results in decreased expression of CASP3 protein
7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Niclosamide results in increased cleavage of CASP3 protein]; [Niclosamide binds to Polyethyleneimine] which results in increased expression of CASP3 mRNA; ATF3 protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Niclosamide results in increased cleavage of CASP3 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP3 protein]; WNT7A protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]		 CTD PMID:20215516 PMID:21871175 PMID:24750999 PMID:25174399 PMID:25634333 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression		 ISO bicalutamide promotes the reaction [Niclosamide results in increased expression of CASP7 protein modified form] CTD PMID:26116531 PMID:28500234 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases cleavage ISO Niclosamide results in increased cleavage of CASP8 protein CTD PMID:35115509 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases cleavage		 ISO TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP9 protein]
Niclosamide results in increased expression of CASP9 mRNA; Niclosamide results in increased expression of CASP9 protein modified form		 CTD PMID:26116531 PMID:26703449 PMID:30258081 PMID:36318118 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cbx4 chromobox 4 increases expression ISO Niclosamide results in increased expression of CBX4 mRNA CTD PMID:36318118 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706 		JBrowse link
G Ccdc113 coiled-coil domain containing 113 increases expression ISO Niclosamide results in increased expression of CFAP263 mRNA CTD PMID:36318118 NCBI chr19:9,497,000...9,516,917
Ensembl chr19:9,496,886...9,516,923 		JBrowse link
G Ccdc188 coiled-coil domain containing 188 increases expression ISO Niclosamide results in increased expression of CCDC188 mRNA CTD PMID:36318118 NCBI chr11:82,769,735...82,772,062
Ensembl chr11:82,769,473...82,772,114 		JBrowse link
G Ccdc68 coiled-coil domain containing 68 decreases expression ISO Niclosamide results in decreased expression of CCDC68 mRNA CTD PMID:36318118 NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL2 mRNA]		 CTD PMID:24561310 PMID:28318631 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of CCL20 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL20 mRNA]		 CTD PMID:28318631 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:24561310 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL5 protein] CTD PMID:24561310 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Niclosamide results in decreased expression of CCNB1 mRNA CTD PMID:28284560 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb3 cyclin B3 decreases expression ISO Niclosamide results in decreased expression of CCNB3 mRNA CTD PMID:36318118 NCBI chr  X:15,478,050...15,543,292
Ensembl chr  X:15,478,065...15,542,885 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression		 EXP
ISO		 Niclosamide inhibits the reaction [Epinephrine results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]]
Niclosamide results in decreased expression of CCND1 mRNA
Niclosamide analog results in decreased expression of CCND1 protein; Niclosamide results in decreased expression of CCND1 mRNA; Niclosamide results in decreased expression of CCND1 protein
Niclosamide inhibits the reaction [IL6 protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of CCND1 protein]		 CTD PMID:19160421 PMID:20215516 PMID:24552774 PMID:24736023 PMID:26297436 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of CCND2 mRNA
Niclosamide results in increased expression of CCND2 mRNA		 CTD PMID:22576131 PMID:27226553 PMID:36318118 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Niclosamide results in decreased expression of CCND3 mRNA CTD PMID:22576131 PMID:27226553 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Niclosamide results in decreased expression of CCNE1 mRNA CTD PMID:36318118 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]
Niclosamide results in decreased expression of CCNE2 mRNA		 CTD PMID:27542212 PMID:36318118 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]
Niclosamide results in increased expression of CCNG2 mRNA		 CTD PMID:27542212 PMID:36318118 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO Niclosamide results in increased expression of CCR10 mRNA CTD PMID:36318118 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988 		JBrowse link
G Cd27 CD27 molecule increases expression ISO Niclosamide results in increased expression of CD27 mRNA CTD PMID:36318118 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Cd274 CD274 molecule decreases expression ISO Niclosamide results in decreased expression of CD274 mRNA; Niclosamide results in decreased expression of CD274 protein CTD PMID:35115509 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD40 protein] CTD PMID:24561310 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Niclosamide results in increased expression of CD55 mRNA CTD PMID:36318118 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd68 Cd68 molecule increases expression ISO Niclosamide results in increased expression of CD68 mRNA CTD PMID:36318118 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD80 protein] CTD PMID:24561310 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD86 protein] CTD PMID:24561310 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions ISO CDC37 protein binds to and results in increased susceptibility to Niclosamide analog CTD PMID:28284560 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
G Cdc42 cell division cycle 42 decreases expression
decreases phosphorylation		 ISO Niclosamide results in decreased expression of CDC42 mRNA
Niclosamide results in decreased phosphorylation of CDC42 protein		 CTD PMID:29251334 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdc42ep1 CDC42 effector protein 1 increases expression ISO Niclosamide results in increased expression of CDC42EP1 mRNA CTD PMID:36318118 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Niclosamide results in decreased expression of CDC6 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Niclosamide results in decreased expression of CDCA2 mRNA CTD PMID:28284560 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca5 cell division cycle associated 5 decreases expression ISO Niclosamide results in decreased expression of CDCA5 mRNA CTD PMID:28284560 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Niclosamide results in decreased expression of CDCA8 mRNA CTD PMID:28284560 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression		 ISO CTNNB1 protein inhibits the reaction [Niclosamide results in increased expression of CDH1 protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in decreased expression of CDH1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased expression of CDH1 protein]
Niclosamide results in increased expression of CDH1 mRNA; Niclosamide results in increased expression of CDH1 protein		 CTD PMID:25174399 PMID:26643609 PMID:30143678 PMID:35115509 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh11 cadherin 11 decreases expression ISO Niclosamide results in decreased expression of CDH11 mRNA CTD PMID:36318118 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdh12 cadherin 12 multiple interactions ISO Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CDH12 protein] CTD PMID:36870549 NCBI chr 2:70,474,679...71,705,369
Ensembl chr 2:70,475,043...71,700,572 		JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of CDH2 protein]
Niclosamide results in decreased expression of CDH2 protein		 CTD PMID:26643609 PMID:34118929 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdh4 cadherin 4 increases expression ISO Niclosamide results in increased expression of CDH4 mRNA CTD PMID:36318118 NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:166,525,099...167,003,371 		JBrowse link
G Cdh6 cadherin 6 decreases expression ISO Niclosamide results in decreased expression of CDH6 mRNA CTD PMID:36318118 NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228 		JBrowse link
G Cdhr1 cadherin-related family member 1 increases expression ISO Niclosamide results in increased expression of CDHR1 mRNA CTD PMID:36318118 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396 		JBrowse link
G Cdhr2 cadherin-related family member 2 decreases expression ISO Niclosamide results in decreased expression of CDHR2 mRNA CTD PMID:36318118 NCBI chr17:9,876,853...9,913,356
Ensembl chr17:9,876,860...9,912,575 		JBrowse link
G Cdk15 cyclin-dependent kinase 15 decreases expression ISO Niclosamide results in decreased expression of CDK15 mRNA CTD PMID:36318118 NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Niclosamide results in decreased expression of CDK2 protein CTD PMID:29031202 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Niclosamide results in decreased expression of CDK4 protein CTD PMID:29031202 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 increases expression ISO Niclosamide results in increased expression of CDKL3 mRNA CTD PMID:36318118 NCBI chr10:36,263,212...36,349,268
Ensembl chr10:36,266,977...36,349,268 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA] CTD PMID:30258081 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Niclosamide results in decreased expression of CDKN3 mRNA CTD PMID:28284560 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Niclosamide results in increased expression of CEBPB mRNA CTD PMID:36318118 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression ISO Niclosamide results in increased expression of CELF6 mRNA CTD PMID:36318118 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041 		JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO Niclosamide results in increased expression of CELSR3 mRNA CTD PMID:28284560 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354 		JBrowse link
G Cenpa centromere protein A decreases expression ISO Niclosamide results in decreased expression of CENPA mRNA CTD PMID:28284560 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpo centromere protein O decreases expression ISO Niclosamide results in decreased expression of CENPO mRNA CTD PMID:36318118 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314 		JBrowse link
G Cenpu centromere protein U decreases expression ISO Niclosamide results in decreased expression of CENPU mRNA CTD PMID:36318118 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cfap70 cilia and flagella associated protein 70 increases expression ISO Niclosamide results in increased expression of CFAP70 mRNA CTD PMID:36318118 NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014 		JBrowse link
G Cfp complement factor properdin increases expression ISO Niclosamide results in increased expression of CFP mRNA CTD PMID:28284560 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Niclosamide results in increased expression of CHAC1 mRNA CTD PMID:36318118 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression ISO Niclosamide results in decreased expression of CHAC2 mRNA CTD PMID:36318118 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO Niclosamide results in decreased expression of CHAF1A mRNA CTD PMID:36318118 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit increases expression ISO Niclosamide results in increased expression of CHRNB1 mRNA CTD PMID:36318118 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chst8 carbohydrate sulfotransferase 8 increases expression ISO Niclosamide results in increased expression of CHST8 mRNA CTD PMID:36318118 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Niclosamide results in decreased phosphorylation of and affects the localization of CHUK protein CTD PMID:26116531 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Niclosamide results in increased expression of CISH mRNA CTD PMID:36318118 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO Niclosamide results in increased expression of CLEC11A mRNA CTD PMID:36318118 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression ISO Niclosamide results in increased expression of CLIP2 mRNA CTD PMID:36318118 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023 		JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 increases expression ISO Niclosamide results in increased expression of CLIP3 mRNA CTD PMID:36318118 NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184 		JBrowse link
G Clspn claspin decreases expression ISO Niclosamide results in decreased expression of CLSPN mRNA CTD PMID:36318118 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Clstn3 calsyntenin 3 increases expression ISO Niclosamide results in increased expression of CLSTN3 mRNA CTD PMID:36318118 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 decreases expression ISO Niclosamide results in decreased expression of CMKLR1 mRNA CTD PMID:36318118 NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO Niclosamide results in decreased expression of CMPK2 mRNA CTD PMID:36318118 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression ISO Niclosamide results in increased expression of CNBD2 mRNA CTD PMID:36318118 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583 		JBrowse link
G Cnn1 calponin 1 increases expression ISO Niclosamide results in increased expression of CNN1 mRNA CTD PMID:36318118 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098 		JBrowse link
G Cnn2 calponin 2 increases expression ISO Niclosamide results in increased expression of CNN2 mRNA CTD PMID:36318118 NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of COL1A1 mRNA
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; Gemcitabine inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; Niclosamide inhibits the reaction [Gemcitabine results in decreased expression of COL1A1 protein]		 CTD PMID:28824321 PMID:35115509 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Niclosamide results in increased expression of COL6A2 mRNA CTD PMID:36318118 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564 		JBrowse link
G Colec10 collectin subfamily member 10 increases expression ISO Niclosamide results in increased expression of COLEC10 mRNA CTD PMID:28284560 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675 		JBrowse link
G Cox8c cytochrome c oxidase subunit 8C increases expression ISO Niclosamide results in increased expression of COX8C mRNA CTD PMID:36318118 NCBI chr 6:122,028,566...122,029,889
Ensembl chr 6:122,028,566...122,029,889 		JBrowse link
G Crb2 crumbs cell polarity complex component 2 increases expression ISO Niclosamide results in increased expression of CRB2 mRNA CTD PMID:36318118 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294 		JBrowse link
G Crebbp CREB binding protein increases expression ISO Niclosamide results in increased expression of CREBBP mRNA CTD PMID:22576131 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Niclosamide results in increased expression of CREBRF mRNA CTD PMID:36318118 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 decreases expression ISO Niclosamide results in decreased expression of CRLF1 mRNA CTD PMID:36318118 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression ISO Niclosamide results in decreased expression of CROT mRNA CTD PMID:36318118 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Crybb1 crystallin, beta B1 increases expression ISO Niclosamide results in increased expression of CRYBB1 mRNA CTD PMID:36318118 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344 		JBrowse link
G Cryl1 crystallin, lambda 1 increases expression ISO Niclosamide results in increased expression of CRYL1 mRNA CTD PMID:36318118 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ITGB3 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OCSTAMP mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OSCAR mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of TRAF6 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK9 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of NFKBIA protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of RELA protein] CTD PMID:28824321 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA] CTD PMID:27542212 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csnk1e casein kinase 1, epsilon increases expression ISO Niclosamide results in increased expression of CSNK1E mRNA CTD PMID:22576131 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Niclosamide results in increased expression of CSRNP1 mRNA CTD PMID:28284560 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Ctbp1 C-terminal binding protein 1 increases expression ISO Niclosamide results in increased expression of CTBP1 mRNA CTD PMID:22576131 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
affects localization
decreases expression
increases ubiquitination
decreases activity
multiple interactions		 ISO
EXP		 Niclosamide results in increased expression of CTNNB1 mRNA
Niclosamide affects the localization of CTNNB1 protein
Niclosamide results in decreased expression of CTNNB1 mRNA
Niclosamide results in increased ubiquitination of CTNNB1 protein
Niclosamide results in decreased activity of CTNNB1 protein
Niclosamide inhibits the reaction [Epinephrine results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]]
Niclosamide analog results in decreased expression of CTNNB1 protein; Niclosamide results in decreased expression of CTNNB1 protein
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of ACTA2 protein]; CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; CTNNB1 protein inhibits the reaction [Niclosamide results in increased expression of CDH1 protein]; Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of CTNNB1 protein]; Niclosamide inhibits the reaction [CTNNB1 protein binds to CTNNBIP1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein results in increased stability of CTNNB1 protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of CTNNB1 protein]; Niclosamide results in decreased expression of and results in increased phosphorylation of CTNNB1 protein		 CTD PMID:19772353 PMID:21531761 PMID:22576131 PMID:24534281 PMID:24552774 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [CTNNB1 protein binds to CTNNBIP1 protein]
Niclosamide results in increased expression of CTNNBIP1 mRNA		 CTD PMID:24534281 PMID:36318118 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Ctsc cathepsin C decreases expression ISO Niclosamide results in decreased expression of CTSC protein CTD PMID:29480568 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsd cathepsin D decreases expression ISO Niclosamide results in decreased expression of CTSD protein CTD PMID:29480568 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:26792726 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Niclosamide results in decreased expression of CXCL12 mRNA CTD PMID:36318118 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of CXCR5 mRNA] CTD PMID:33632240 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cyb561 cytochrome b-561 decreases expression ISO Niclosamide results in decreased expression of CYB561 mRNA CTD PMID:36318118 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO Niclosamide results in increased expression of CYCS protein CTD PMID:26703449 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO Niclosamide results in increased activity of CYP1A1 protein CTD PMID:12451431 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression		 ISO Niclosamide results in decreased activity of CYP1A2 protein
Niclosamide results in increased expression of CYP1A2 mRNA		 CTD PMID:11124226 PMID:28284560 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO Niclosamide results in increased expression of CYP27A1 mRNA CTD PMID:36318118 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Niclosamide results in decreased activity of CYP2D6 protein CTD PMID:11124226 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression ISO Niclosamide results in increased expression of CYP39A1 mRNA CTD PMID:28284560 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Niclosamide results in decreased activity of CYP3A4 protein CTD PMID:11124226 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 increases expression ISO Niclosamide results in increased expression of DACT3 mRNA CTD PMID:36318118 NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression ISO Niclosamide results in increased expression of DBP mRNA CTD PMID:36318118 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent increases expression ISO Niclosamide results in increased expression of DDAH2 mRNA CTD PMID:36318118 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO Niclosamide results in decreased expression of DDIAS mRNA CTD PMID:36318118 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of DDIT3 mRNA; Niclosamide results in increased expression of DDIT3 protein
ATF3 protein affects the reaction [Niclosamide results in increased expression of DDIT3 mRNA]		 CTD PMID:26917416 PMID:36318118 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Niclosamide results in increased expression of DDIT4 mRNA CTD PMID:36318118 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Niclosamide results in increased expression of DDR1 mRNA CTD PMID:36318118 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 decreases expression ISO Niclosamide results in decreased expression of DECR1 mRNA CTD PMID:22576131 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit decreases expression ISO Niclosamide results in decreased expression of DGCR8 mRNA CTD PMID:36318118 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242 		JBrowse link
G Dgkb diacylglycerol kinase, beta increases expression ISO Niclosamide results in increased expression of DGKB mRNA CTD PMID:36318118 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Niclosamide results in decreased expression of DHFR mRNA CTD PMID:36318118 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Niclosamide results in increased expression of DHRS3 mRNA CTD PMID:36318118 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Niclosamide results in decreased expression of DKK1 mRNA CTD PMID:36318118 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Niclosamide results in increased expression of DLG4 mRNA CTD PMID:36318118 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like decreases expression ISO Niclosamide results in decreased expression of DMAC2L mRNA CTD PMID:22576131 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Niclosamide results in decreased expression of DNAJA1 mRNA CTD PMID:36318118 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 decreases expression ISO Niclosamide results in decreased expression of DNAJA4 mRNA CTD PMID:36318118 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207 		JBrowse link
G Dnajc22 DnaJ heat shock protein family (Hsp40) member C22 increases expression ISO Niclosamide results in increased expression of DNAJC22 mRNA CTD PMID:36318118 NCBI chr 7:130,257,504...130,262,880
Ensembl chr 7:130,257,851...130,263,230 		JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 decreases expression ISO Niclosamide results in decreased expression of DNAJC9 mRNA CTD PMID:36318118 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118 		JBrowse link
G Dock5 dedicator of cytokinesis 5 decreases expression ISO Niclosamide results in decreased expression of DOCK5 mRNA CTD PMID:36318118 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649 		JBrowse link
G Dqx1 DEAQ box RNA-dependent ATPase 1 increases expression ISO Niclosamide results in increased expression of DQX1 mRNA CTD PMID:36318118 NCBI chr 4:115,563,497...115,572,598
Ensembl chr 4:115,563,752...115,572,590 		JBrowse link
G Drd4 dopamine receptor D4 increases expression ISO Niclosamide results in increased expression of DRD4 mRNA CTD PMID:36318118 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] CTD PMID:27542212 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Niclosamide results in decreased expression of DTL mRNA CTD PMID:36318118 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Niclosamide results in increased expression of DUSP4 mRNA CTD PMID:36318118 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO Niclosamide results in increased expression of DUSP8 mRNA CTD PMID:36318118 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Dusp9 dual specificity phosphatase 9 increases expression ISO Niclosamide results in increased expression of DUSP9 mRNA CTD PMID:36318118 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 increases expression ISO Niclosamide results in increased expression of DVL1 mRNA CTD PMID:22576131 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 decreases expression
multiple interactions		 ISO
EXP		 Niclosamide results in decreased expression of DVL2 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]]		 CTD PMID:19772353 PMID:21531761 PMID:30143678 PMID:32961231 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression ISO Niclosamide results in increased expression of DVL3 mRNA CTD PMID:22576131 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B increases expression ISO Niclosamide results in increased expression of DYRK1B mRNA CTD PMID:36318118 NCBI chr 1:83,479,168...83,497,011
Ensembl chr 1:83,479,147...83,487,169 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Niclosamide results in decreased expression of E2F1 mRNA CTD PMID:29843133 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Niclosamide results in decreased expression of E2F2 mRNA CTD PMID:36318118 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G E2f7 E2F transcription factor 7 decreases expression ISO Niclosamide results in decreased expression of E2F7 mRNA CTD PMID:36318118 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Niclosamide results in decreased expression of E2F8 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Eaf2 ELL associated factor 2 decreases expression ISO Niclosamide results in decreased expression of EAF2 mRNA CTD PMID:36318118 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610 		JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Niclosamide results in decreased expression of EBF1 mRNA CTD PMID:27226553 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665 		JBrowse link
G Ebf4 EBF family member 4 increases expression ISO Niclosamide results in increased expression of EBF4 mRNA CTD PMID:36318118 NCBI chr 3:117,498,186...117,566,566
Ensembl chr 3:117,498,319...117,566,566 		JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO Niclosamide results in decreased expression of ECHDC1 mRNA CTD PMID:22576131 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319 		JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression ISO Niclosamide results in decreased expression of ECHDC2 mRNA CTD PMID:36318118 NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Niclosamide results in decreased expression of ECHS1 mRNA CTD PMID:22576131 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Efna1 ephrin A1 increases expression ISO Niclosamide results in increased expression of EFNA1 mRNA CTD PMID:36318118 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Efna3 ephrin A3 increases expression ISO Niclosamide results in increased expression of EFNA3 mRNA CTD PMID:36318118 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efnb3 ephrin B3 increases expression ISO Niclosamide results in increased expression of EFNB3 mRNA CTD PMID:36318118 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471 		JBrowse link
G Egf epidermal growth factor decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of EGF mRNA; Niclosamide results in decreased expression of EGF protein
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein binds to EGFR protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Niclosamide inhibits the reaction [EGF protein binds to EGFR protein]; Niclosamide inhibits the reaction [EGF protein results in increased expression of HIF1A mRNA]; Niclosamide inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]		 CTD PMID:30779072 PMID:38185387 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression
multiple interactions
decreases phosphorylation		 ISO Niclosamide analog results in decreased expression of EGFR protein; Niclosamide results in decreased expression of EGFR mRNA; Niclosamide results in decreased expression of EGFR protein
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein binds to EGFR protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Niclosamide inhibits the reaction [EGF protein binds to EGFR protein]
Niclosamide results in decreased phosphorylation of EGFR protein		 CTD PMID:28284560 PMID:28426875 PMID:30779072 PMID:38185387 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression		 ISO Niclosamide results in increased expression of EGR1 mRNA
Niclosamide results in decreased expression of EGR1 mRNA		 CTD PMID:28284560 PMID:36318118 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of EIF2AK3 mRNA
ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA]; Niclosamide results in increased expression of and results in increased phosphorylation of EIF2AK3 protein		 CTD PMID:26917416 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Niclosamide results in increased phosphorylation of EIF2S1 protein CTD PMID:26917416 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression ISO Niclosamide results in increased expression of EIF4A2 mRNA CTD PMID:36318118 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression
multiple interactions
decreases phosphorylation		 ISO Niclosamide analog results in decreased expression of EIF4EBP1 protein modified form; Niclosamide results in decreased expression of EIF4EBP1 protein modified form
Niclosamide inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
Niclosamide results in decreased phosphorylation of EIF4EBP1 protein		 CTD PMID:19771169 PMID:28284560 PMID:30258081 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO Niclosamide results in increased expression of ELF1 mRNA CTD PMID:36318118 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699 		JBrowse link
G Elfn1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 increases expression ISO Niclosamide results in increased expression of ELFN1 mRNA CTD PMID:36318118 NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580 		JBrowse link
G Eml2 EMAP like 2 increases expression ISO Niclosamide results in increased expression of EML2 mRNA CTD PMID:36318118 NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341 		JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] CTD PMID:27542212 NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892 		JBrowse link
G Eng endoglin increases expression ISO Niclosamide results in increased expression of ENG mRNA CTD PMID:36318118 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Eno2 enolase 2 increases expression ISO Niclosamide results in increased expression of ENO2 mRNA CTD PMID:22576131 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Eno3 enolase 3 decreases expression ISO Niclosamide results in decreased expression of ENO3 mRNA CTD PMID:22576131 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Niclosamide results in increased expression of EP300 mRNA CTD PMID:22576131 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:36318118 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epha8 Eph receptor A8 increases expression ISO Niclosamide results in increased expression of EPHA8 mRNA CTD PMID:36318118 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Eps8l3 EPS8 like 3 increases expression ISO Niclosamide results in increased expression of EPS8L3 mRNA CTD PMID:28284560 NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085 		JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase increases expression ISO Niclosamide results in increased expression of ETHE1 mRNA CTD PMID:36318118 NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052 		JBrowse link
G Eva1b eva-1 homolog B increases expression ISO Niclosamide results in increased expression of EVA1B mRNA CTD PMID:36318118 NCBI chr 5:138,427,088...138,429,602
Ensembl chr 5:138,427,151...138,432,433 		JBrowse link
G Exo5 exonuclease 5 decreases expression ISO Niclosamide results in decreased expression of EXO5 mRNA CTD PMID:36318118 NCBI chr 5:134,494,440...134,497,757
Ensembl chr 5:134,493,829...134,497,772 		JBrowse link
G Exog exo/endonuclease G decreases expression ISO Niclosamide results in decreased expression of EXOG mRNA CTD PMID:36318118 NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G F10 coagulation factor X increases expression ISO Niclosamide results in increased expression of F10 mRNA CTD PMID:36318118 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F12 coagulation factor XII increases expression ISO Niclosamide results in increased expression of F12 mRNA CTD PMID:36318118 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Fam131c family with sequence similarity 131, member C increases expression ISO Niclosamide results in increased expression of FAM131C mRNA CTD PMID:36318118 NCBI chr 5:153,674,459...153,690,791
Ensembl chr 5:153,671,772...153,690,800 		JBrowse link
G Fam135b family with sequence similarity 135, member B increases expression ISO Niclosamide results in increased expression of FAM135B mRNA CTD PMID:36318118 NCBI chr 7:103,380,981...103,649,802
Ensembl chr 7:103,386,915...103,649,708 		JBrowse link
G Fam13b family with sequence similarity 13, member B decreases expression ISO Niclosamide results in decreased expression of FAM13B mRNA CTD PMID:36318118 NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587 		JBrowse link
G Fam221a family with sequence similarity 221, member A increases expression ISO Niclosamide results in increased expression of FAM221A mRNA CTD PMID:36318118 NCBI chr 4:78,337,296...78,358,918
Ensembl chr 4:78,337,296...78,358,909 		JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO Niclosamide results in increased expression of FAM43A mRNA CTD PMID:36318118 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401 		JBrowse link
G Fam43b family with sequence similarity 43, member B increases expression ISO Niclosamide results in increased expression of FAM43B mRNA CTD PMID:36318118 NCBI chr 5:150,610,656...150,613,054
Ensembl chr 5:150,611,609...150,612,601 		JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO Niclosamide results in decreased expression of FAM83D mRNA CTD PMID:28284560 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fancb FA complementation group B decreases expression ISO Niclosamide results in decreased expression of FANCB mRNA CTD PMID:36318118 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO
EXP		 Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of CXCR5 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL21 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL6 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of PRDM1 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of TCF7 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the phosphorylation of STAT3 protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of FAS mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FAS mRNA]		 CTD PMID:28318631 PMID:33632240 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fastkd3 FAST kinase domains 3 decreases expression ISO Niclosamide results in decreased expression of FASTKD3 mRNA CTD PMID:36318118 NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973 		JBrowse link
G Fbxo2 F-box protein 2 increases expression ISO Niclosamide results in increased expression of FBXO2 mRNA CTD PMID:36318118 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355 		JBrowse link
G Fbxo48 F-box protein 48 increases expression ISO Niclosamide results in increased expression of FBXO48 mRNA CTD PMID:36318118 NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314 		JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 increases expression ISO Niclosamide results in increased expression of FCHO1 mRNA CTD PMID:36318118 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104 		JBrowse link
G Fcrlb Fc receptor-like B increases expression ISO Niclosamide results in increased expression of FCRLB mRNA CTD PMID:36318118 NCBI chr13:83,148,685...83,157,157
Ensembl chr13:83,149,751...83,155,957 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO Niclosamide results in decreased expression of FEN1 mRNA CTD PMID:36318118 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fgd1 FYVE, RhoGEF and PH domain containing 1 increases expression ISO Niclosamide results in increased expression of FGD1 mRNA CTD PMID:36318118 NCBI chr  X:20,023,746...20,066,734
Ensembl chr  X:20,023,746...20,066,566 		JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Niclosamide results in decreased expression of FGF1 mRNA; Niclosamide results in decreased expression of FGF1 protein CTD PMID:25174399 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf19 fibroblast growth factor 19 increases expression ISO Niclosamide results in increased expression of FGF19 mRNA CTD PMID:36318118 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression ISO Niclosamide results in increased expression of FGFR4 mRNA CTD PMID:36318118 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fignl1 fidgetin-like 1 decreases expression ISO Niclosamide results in decreased expression of FIGNL1 mRNA CTD PMID:36318118 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
decreases expression		 ISO [Niclosamide co-treated with bicalutamide] results in decreased expression of FKBP5 mRNA
Niclosamide results in decreased expression of FKBP5 mRNA		 CTD PMID:28500234 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 decreases expression ISO Niclosamide results in decreased expression of FLRT3 mRNA CTD PMID:36318118 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841 		JBrowse link
G Fmn1 formin 1 increases expression ISO Niclosamide results in increased expression of FMN1 mRNA CTD PMID:36318118 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of FN1 protein]
HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]		 CTD PMID:28318631 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fndc10 fibronectin type III domain containing 10 increases expression ISO Niclosamide results in increased expression of FNDC10 mRNA CTD PMID:36318118 NCBI chr 5:166,299,587...166,311,477
Ensembl chr 5:166,300,122...166,310,326 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Niclosamide results in increased expression of FNDC4 mRNA CTD PMID:36318118 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]
Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]		 CTD PMID:26792726 PMID:28824321 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Niclosamide results in increased expression of FOSB mRNA CTD PMID:28284560 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Niclosamide results in increased expression of FOSL1 mRNA CTD PMID:22576131 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxl1 forkhead box L1 increases expression ISO Niclosamide results in increased expression of FOXL1 mRNA CTD PMID:36318118 NCBI chr19:49,197,269...49,200,682
Ensembl chr19:49,197,400...49,198,425 		JBrowse link
G Foxm1 forkhead box M1 multiple interactions
decreases expression		 ISO Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of FOXM1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of FOXM1 protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of FOXM1 protein] CTD PMID:27492973 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo4 forkhead box O4 increases expression ISO Niclosamide results in increased expression of FOXO4 mRNA CTD PMID:36318118 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Foxo6 forkhead box O6 increases expression ISO Niclosamide results in increased expression of FOXO6 mRNA CTD PMID:36318118 NCBI chr 5:133,856,087...133,876,387
Ensembl chr 5:133,856,072...133,876,573 		JBrowse link
G Frat2 FRAT regulator of WNT signaling pathway 2 increases expression ISO Niclosamide results in increased expression of FRAT2 mRNA CTD PMID:36318118 NCBI chr 1:240,654,120...240,656,449
Ensembl chr 1:240,654,137...240,656,517 		JBrowse link
G Frzb frizzled-related protein increases expression ISO Niclosamide results in increased expression of FRZB mRNA CTD PMID:36318118 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions ISO Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of FSCN1 mRNA] CTD PMID:29733962 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fstl3 follistatin like 3 increases expression ISO Niclosamide results in increased expression of FSTL3 mRNA CTD PMID:36318118 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639 		JBrowse link
G Fzd1 frizzled class receptor 1 affects localization ISO Niclosamide affects the localization of FZD1 protein CTD PMID:19772353 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of FZD2 mRNA
Niclosamide results in increased expression of FZD2 mRNA		 CTD PMID:22576131 PMID:36318118 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Fzd5 frizzled class receptor 5 increases expression ISO Niclosamide results in increased expression of FZD5 mRNA CTD PMID:22576131 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Fzd9 frizzled class receptor 9 decreases expression ISO Niclosamide results in decreased expression of FZD9 mRNA CTD PMID:22576131 NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398 		JBrowse link
G G4 G4 protein affects expression ISO Niclosamide affects the expression of C6ORF47 mRNA CTD PMID:36318118 NCBI chr20:3,693,691...3,696,194
Ensembl chr20:3,693,649...3,696,088 		JBrowse link
G Gab2 GRB2-associated binding protein 2 increases expression ISO Niclosamide results in increased expression of GAB2 mRNA CTD PMID:36318118 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Niclosamide results in increased expression of GABARAPL1 mRNA CTD PMID:36318118 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression ISO Niclosamide results in increased expression of GABRA4 mRNA CTD PMID:36318118 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Niclosamide results in increased expression of GABRB1 mRNA CTD PMID:36318118 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Niclosamide results in increased expression of GADD45B mRNA CTD PMID:36318118 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Garin1a golgi associated RAB2 interactor 1A increases expression ISO Niclosamide results in increased expression of GARIN1A mRNA CTD PMID:36318118 NCBI chr 4:57,880,019...57,890,824
Ensembl chr 4:57,880,019...57,890,820 		JBrowse link
G Gata5 GATA binding protein 5 increases expression ISO Niclosamide results in increased expression of GATA5 mRNA CTD PMID:36318118 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Gcg glucagon multiple interactions EXP Niclosamide inhibits the reaction [GCG protein results in increased abundance of Cyclic AMP]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein] CTD PMID:26964897 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Niclosamide results in decreased expression of GCLM mRNA CTD PMID:36318118 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Niclosamide results in increased expression of GDF15 mRNA CTD PMID:36318118 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 increases expression ISO Niclosamide results in increased expression of GDPD5 mRNA CTD PMID:36318118 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446 		JBrowse link
G Gdpgp1 GDP-D-glucose phosphorylase 1 decreases expression ISO Niclosamide results in decreased expression of GDPGP1 mRNA CTD PMID:36318118 NCBI chr 1:134,184,119...134,193,281
Ensembl chr 1:134,183,696...134,219,783 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Niclosamide results in decreased expression of GFAP protein CTD PMID:34118929 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gid4 GID complex subunit 4 increases expression ISO Niclosamide results in increased expression of GID4 mRNA CTD PMID:36318118 NCBI chr10:45,221,556...45,247,627
Ensembl chr10:45,245,754...45,247,621
Ensembl chr10:45,245,754...45,247,621 		JBrowse link
G Gins1 GINS complex subunit 1 decreases expression ISO Niclosamide results in decreased expression of GINS1 mRNA CTD PMID:36318118 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO Niclosamide results in decreased expression of GINS2 mRNA CTD PMID:36318118 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins3 GINS complex subunit 3 decreases expression ISO Niclosamide results in decreased expression of GINS3 mRNA CTD PMID:36318118 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 decreases expression ISO Niclosamide results in decreased expression of GINS4 mRNA CTD PMID:36318118 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Glb1l3 galactosidase, beta 1-like 3 decreases expression ISO Niclosamide results in decreased expression of GLB1L3 mRNA CTD PMID:36318118 NCBI chr 8:25,179,165...25,220,904
Ensembl chr 8:25,179,165...25,220,904 		JBrowse link
G Glis1 GLIS family zinc finger 1 increases expression ISO Niclosamide results in increased expression of GLIS1 mRNA CTD PMID:36318118 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141 		JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Niclosamide results in increased expression of GLIS2 mRNA CTD PMID:36318118 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578 		JBrowse link
G Gng7 G protein subunit gamma 7 increases expression ISO Niclosamide results in increased expression of GNG7 mRNA CTD PMID:36318118 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240 		JBrowse link
G Golga2 golgin A2 increases expression ISO Niclosamide results in increased expression of GOLGA2 mRNA CTD PMID:36318118 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279 		JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO Niclosamide results in decreased expression of GOSR2 mRNA CTD PMID:36318118 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression ISO Niclosamide results in increased expression of GOT2 mRNA CTD PMID:22576131 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta increases expression ISO Niclosamide results in increased expression of GP1BB mRNA CTD PMID:36318118 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gpc2 glypican 2 increases expression ISO Niclosamide results in increased expression of GPC2 mRNA CTD PMID:36318118 NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208 		JBrowse link
G Gpr153 G protein-coupled receptor 153 increases expression ISO Niclosamide results in increased expression of GPR153 mRNA CTD PMID:36318118 NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971 		JBrowse link
G Gpr75 G protein-coupled receptor 75 decreases expression ISO Niclosamide results in decreased expression of GPR75 mRNA CTD PMID:36318118 NCBI chr14:104,609,542...104,618,885
Ensembl chr14:104,611,089...104,620,370 		JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C increases expression ISO Niclosamide results in increased expression of GPRC5C mRNA CTD PMID:36318118 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926 		JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist decreases expression ISO Niclosamide results in decreased expression of GREM2 mRNA CTD PMID:36318118 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO Niclosamide results in increased expression of GRIK5 mRNA CTD PMID:36318118 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D increases expression ISO Niclosamide results in increased expression of GRIN2D mRNA CTD PMID:36318118 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression ISO Niclosamide results in increased expression of GRIP2 mRNA CTD PMID:36318118 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
increases phosphorylation
decreases phosphorylation		 ISO Niclosamide results in decreased expression of GSK3B mRNA
Niclosamide results in increased phosphorylation of GSK3B protein
Niclosamide results in decreased phosphorylation of GSK3B protein		 CTD PMID:22576131 PMID:30143678 PMID:35115509 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstt2 glutathione S-transferase theta 2 decreases expression ISO Niclosamide results in decreased expression of GSTT2 mRNA CTD PMID:36318118 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of GTF2H4 mRNA
Niclosamide results in increased expression of GTF2H4 mRNA		 CTD PMID:36318118 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 decreases expression ISO Niclosamide results in decreased expression of GTSE1 mRNA CTD PMID:28284560 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 increases expression ISO Niclosamide results in increased expression of GXYLT2 mRNA CTD PMID:36318118 NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Niclosamide results in decreased expression of HADH mRNA CTD PMID:22576131 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
increases expression		 ISO Niclosamide results in decreased expression of HAMP mRNA
Niclosamide results in increased expression of HAMP mRNA		 CTD PMID:25633564 PMID:28284560 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]
Niclosamide results in increased expression of HBP1 mRNA		 CTD PMID:27542212 PMID:36318118 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hdac5 histone deacetylase 5 increases expression ISO Niclosamide results in increased expression of HDAC5 mRNA CTD PMID:36318118 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Helz2 helicase with zinc finger 2 increases expression ISO Niclosamide results in increased expression of HELZ2 mRNA CTD PMID:36318118 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
multiple interactions		 ISO
EXP		 Niclosamide results in decreased expression of HES1 protein
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HES1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HES1 mRNA]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]]		 CTD PMID:19160421 PMID:28318631 PMID:32961231 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY1 mRNA]
Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]		 CTD PMID:27542212 PMID:28318631 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression		 EXP
ISO		 Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY2 mRNA]
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY2 mRNA]
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Niclosamide results in increased expression of HEY2 mRNA]		 CTD PMID:19160421 PMID:28318631 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Hhipl1 HHIP-like 1 increases expression ISO Niclosamide results in increased expression of HHIPL1 mRNA CTD PMID:36318118 NCBI chr 6:127,219,616...127,243,839
Ensembl chr 6:127,220,014...127,242,564 		JBrowse link
G Hid1 HID1 domain containing increases expression ISO Niclosamide results in increased expression of HID1 mRNA CTD PMID:36318118 NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of HIF1A mRNA; Niclosamide results in decreased expression of HIF1A protein
Niclosamide inhibits the reaction [EGF protein results in increased expression of HIF1A mRNA]; Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]		 CTD PMID:30779072 PMID:36318118 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 protein]
HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Niclosamide inhibits the reaction [TGFB1 protein promotes the reaction [SMAD3 protein binds to HIPK2 promoter]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]		 CTD PMID:28318631 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Niclosamide results in increased expression of H2BC21 mRNA CTD PMID:36318118 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hivep2 HIVEP zinc finger 2 increases expression ISO Niclosamide results in increased expression of HIVEP2 mRNA CTD PMID:36318118 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993 		JBrowse link
G Hk3 hexokinase 3 decreases expression ISO Niclosamide results in decreased expression of HK3 mRNA CTD PMID:36318118 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase increases expression ISO Niclosamide results in increased expression of HMGCL mRNA CTD PMID:36318118 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Niclosamide results in decreased expression of HMMR mRNA CTD PMID:28284560 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmx2 H6 family homeobox 2 increases expression ISO Niclosamide results in increased expression of HMX2 mRNA CTD PMID:36318118 NCBI chr 1:186,319,110...186,326,771
Ensembl chr 1:186,319,110...186,326,771