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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chrysen-6-ol
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Accession:CHEBI:132407 term browser browse the term
Definition:A hydroxychrysene that is chrysene in which the hydrogen at position 6 has been replaced by a hydroxy group. It is a metabolite of the polycyclic aromatic hydrocarbon chrysene.
Synonyms:related_synonym: 6-chrysenol;   6-hydroxychrysene;   Formula=C18H12O;   InChI=1S/C18H12O/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11,19H;   InChIKey=VXFDOYXVHRYCGS-UHFFFAOYSA-N;   SMILES=C=1C=CC=C2C3=CC=C4C=CC=CC4=C3C=C(C21)O
 xref: CAS:37515-51-8
 xref_mesh: MESH:C087203
 xref: Reaxys:1970026


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chrysen-6-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgr progesterone receptor multiple interactions ISO 6-hydroxychrysene inhibits the reaction [Progesterone binds to PGR protein]; [Progesterone co-treated with 6-hydroxychrysene] results in decreased expression of PGR mRNA CTD PMID:9144411 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
multiple interactions		 EXP UGT1A1 protein results in increased glucuronidation of 6-hydroxychrysene
[Methylcholanthrene results in increased expression of UGT1A1 protein] which results in increased glucuronidation of 6-hydroxychrysene		 CTD PMID:1435739 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases glucuronidation ISO UGT1A6 protein results in increased glucuronidation of 6-hydroxychrysene CTD PMID:7786300 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        biochemical role 19556
          metabolite 19544
            xenobiotic metabolite 16162
              chrysen-6-ol 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            organic hydride 18691
                              organic fundamental parent 18691
                                hydrocarbon 18442
                                  cyclic hydrocarbon 17235
                                    arene 17216
                                      polycyclic arene 17041
                                        ortho-fused polycyclic arene 9838
                                          chrysene 879
                                            hydroxychrysene 3
                                              chrysen-6-ol 3
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