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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sodium perchlorate
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Accession:CHEBI:132103 term browser browse the term
Definition:An inorganic sodium salt comprising equal numbers of sodium and perchlorate ions.
Synonyms:related_synonym: Formula=ClNaO4;   InChI=1S/ClHO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1;   InChIKey=BAZAXWOYCMUHIX-UHFFFAOYSA-M;   NaClO4;   Natriumperchlorat;   Perchlorate de sodium;   Perchloric acid, sodium salt;   SMILES=[Na+].O=Cl([O-])(=O)=O
 xref: CAS:7601-89-0
 xref_mesh: MESH:C031068
 xref: PMID:25623150;   PMID:25865142;   Reaxys:15953031;   Reaxys:16152416;   Reaxys:16179164;   Reaxys:17314039;   Wikipedia:Sodium_perchlorate


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sodium perchlorate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH1L1 protein CTD PMID:30090431 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH5A1 protein CTD PMID:30090431 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP sodium perchlorate results in increased expression of CGA mRNA; sodium perchlorate results in increased expression of CGA protein CTD PMID:29139221 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of CTH protein CTD PMID:30090431 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of CYB5A protein CTD PMID:30090431 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP sodium perchlorate results in decreased expression of DIO1 mRNA CTD PMID:29139221 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [sodium perchlorate results in increased abundance of perchlorate] which results in increased expression of FOS protein CTD PMID:30991129 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of FTCD protein CTD PMID:30090431 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of GAMT protein CTD PMID:30090431 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Ifng interferon gamma increases expression
multiple interactions		 EXP sodium perchlorate results in increased expression of IFNG mRNA
sodium perchlorate results in increased expression of and results in increased secretion of IFNG protein		 CTD PMID:29139221 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1a interleukin 1 alpha increases expression EXP sodium perchlorate results in increased expression of IL1A mRNA CTD PMID:29139221 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 EXP sodium perchlorate results in increased expression of and results in increased secretion of IL6 protein
sodium perchlorate results in increased expression of IL6 mRNA		 CTD PMID:29139221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Krt18 keratin 18 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of KRT18 protein CTD PMID:30090431 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166 		JBrowse link
G Lep leptin multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of LEP protein CTD PMID:30090431 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased secretion of LHB protein CTD PMID:30090431 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Nkx2-1 NK2 homeobox 1 increases expression EXP sodium perchlorate results in increased expression of NKX2-1 protein CTD PMID:29139221 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Pax8 paired box 8 increases expression EXP sodium perchlorate results in increased expression of PAX8 protein CTD PMID:29139221 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein; [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pon2 paraoxonase 2 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON2 protein CTD PMID:30090431 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression
decreases activity		 ISO
EXP		 sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Technetium]
sodium perchlorate results in increased expression of SLC5A5 mRNA; sodium perchlorate results in increased expression of SLC5A5 protein
sodium perchlorate results in decreased activity of SLC5A5 protein		 CTD PMID:12488351 PMID:12489024 PMID:12541134 PMID:15221289 PMID:15520214 More... NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tg thyroglobulin increases expression EXP sodium perchlorate results in increased expression of TG protein CTD PMID:29139221 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP sodium perchlorate results in increased expression of TNF mRNA
sodium perchlorate results in increased expression of and results in increased secretion of TNF protein		 CTD PMID:29139221 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpo thyroid peroxidase decreases activity
increases expression		 EXP sodium perchlorate results in decreased activity of TPO protein
sodium perchlorate results in increased expression of TPO mRNA; sodium perchlorate results in increased expression of TPO protein		 CTD PMID:23959146 PMID:29139221 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Trh thyrotropin releasing hormone decreases expression
increases expression		 EXP sodium perchlorate results in decreased expression of TRH protein
sodium perchlorate results in increased expression of TRH mRNA		 CTD PMID:29139221 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions
increases expression		 ISO
EXP		 sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]]
[Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of TSHB protein
sodium perchlorate results in increased expression of TSHB mRNA; sodium perchlorate results in increased expression of TSHB protein		 CTD PMID:16030158 PMID:29139221 PMID:30090431 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression EXP sodium perchlorate results in increased expression of TSHR mRNA; sodium perchlorate results in increased expression of TSHR protein CTD PMID:29139221 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      molecular entity 19872
        inorganic molecular entity 19660
          inorganic salt 15549
            inorganic sodium salt 13215
              sodium perchlorate 26
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      chalcogen 19563
                        oxygen atom 19535
                          oxygen molecular entity 19535
                            oxide 12868
                              oxoanion 10448
                                halogen oxoanion 248
                                  chlorine oxoanion 86
                                    perchlorate 45
                                      sodium perchlorate 26
paths to the root