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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
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Accession:CHEBI:102248 term browser browse the term
Definition:An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).
Synonyms:related_synonym: EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors;   EC 1.14.11.29 inhibitor;   EC 1.14.11.29 inhibitors;   HIF hydroxylase inhibitor;   HIF hydroxylase inhibitors;   hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor;   hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors;   prolyl 4-hydroxylase inhibitor;   prolyl 4-hydroxylase inhibitors

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  CHEBI ontology 0
    role 0
      biological role 0
        biochemical role 0
          enzyme inhibitor 0
            EC 1.* (oxidoreductase) inhibitor 0
              EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 0
                EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor 0
                  EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor 0
                    daprodustat 0
                    dimethyloxalylglycine 0
                    roxadustat 0
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