CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | zearalenone |
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Accession: | CHEBI:10106
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browse the term
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Definition: | A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species. |
Synonyms: | exact_synonym: | (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione |
| related_synonym: | (10S)-Zearalenone; (S)-Zearalenone; (S-(E))-3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; 6-(10-Hydroxy-6-oxo-trans-1-undecenyl)-beta-resorcylic acid lactone; Formula=C18H22O5; InChI=1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1; InChIKey=MBMQEIFVQACCCH-QBODLPLBSA-N; SMILES=C[C@H]1CCCC(=O)CCC\\C=C\\c2cc(O)cc(O)c2C(=O)O1; trans-Zearalenone |
| xref: | AGR:IND608145868; CAS:17924-92-4; KEGG:C09981; KNApSAcK:C00003025; LIPID_MAPS_instance:LMPK04000016 |
| xref_mesh: | MESH:D015025 |
| xref: | PMID:17339071; PMID:18027362; PMID:18221829; PMID:18280460; PMID:18692541; PMID:20654554; PMID:38449531; Reaxys:4875541 |
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Aars1 |
alanyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of AARS1 protein |
CTD |
PMID:25058043 PMID:36252740 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions increases expression decreases expression affects expression |
EXP |
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCB1A mRNA] Zearalenone results in increased expression of ABCB1 mRNA; Zearalenone results in increased expression of ABCB1A mRNA Zearalenone results in decreased expression of ABCB1A mRNA Zearalenone affects the expression of ABCB1A protein |
CTD |
PMID:20607812 PMID:22521637 PMID:23707492 PMID:29627501 |
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NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
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Abcb1b |
ATP-binding cassette, sub-family B member 1B |
decreases expression increases expression |
EXP |
Zearalenone results in decreased expression of ABCB1B mRNA Zearalenone results in increased expression of ABCB1B mRNA; Zearalenone results in increased expression of ABCB1B protein |
CTD |
PMID:22521637 PMID:23707492 |
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NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199
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Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression increases transport multiple interactions affects expression decreases expression |
ISO EXP |
Zearalenone results in increased expression of ABCC1 protein ABCC1 protein results in increased transport of Zearalenone verlukast inhibits the reaction [ABCC1 protein results in increased transport of Zearalenone]; Zearalenone inhibits the reaction [ABCC1 protein results in increased transport of calcein AM] Zearalenone affects the expression of ABCC1 mRNA; Zearalenone affects the expression of ABCC1 protein Zearalenone results in decreased expression of ABCC1 mRNA; Zearalenone results in decreased expression of ABCC1 protein |
CTD |
PMID:19580841 PMID:19647055 PMID:22521637 PMID:23707492 |
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NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
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Abcc2 |
ATP binding cassette subfamily C member 2 |
increases expression multiple interactions increases transport |
ISO |
Zearalenone results in increased expression of ABCC2 mRNA verlukast inhibits the reaction [ABCC2 protein results in increased transport of Zearalenone]; Zearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM] |
CTD |
PMID:19580841 PMID:19647055 |
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NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
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Abcc3 |
ATP binding cassette subfamily C member 3 |
decreases expression multiple interactions affects expression |
ISO EXP |
Zearalenone results in decreased expression of ABCC3 mRNA Zearalenone inhibits the reaction [ABCC3 protein results in increased transport of calcein AM] Zearalenone affects the expression of ABCC3 mRNA; Zearalenone affects the expression of ABCC3 protein |
CTD |
PMID:19371625 PMID:19647055 PMID:22521637 |
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NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
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Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions decreases expression increases expression |
EXP |
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC4 mRNA] Zearalenone results in decreased expression of ABCC4 protein Zearalenone results in increased expression of ABCC4 mRNA; Zearalenone results in increased expression of ABCC4 protein |
CTD |
PMID:23707492 |
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NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283
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Abcc5 |
ATP binding cassette subfamily C member 5 |
multiple interactions affects expression increases expression decreases expression |
EXP |
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC5 mRNA] Zearalenone affects the expression of ABCC5 protein Zearalenone results in decreased expression of ABCC5 mRNA |
CTD |
PMID:23707492 PMID:29627501 |
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NCBI chr11:93,975,579...94,071,659
Ensembl chr11:80,473,872...80,567,253
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Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression decreases expression increases transport |
ISO EXP |
Zearalenone results in increased expression of ABCG2 mRNA Zearalenone results in increased expression of ABCG2 mRNA; Zearalenone results in increased expression of ABCG2 protein Zearalenone results in decreased expression of ABCG2 mRNA; Zearalenone results in decreased expression of ABCG2 protein ABCG2 protein results in increased transport of Zearalenone |
CTD |
PMID:19580841 PMID:22521637 PMID:23707492 PMID:30576553 |
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NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
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Abracl |
ABRA C-terminal like |
decreases expression |
ISO |
Zearalenone results in decreased expression of ABRACL protein |
CTD |
PMID:36252740 |
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NCBI chr 1:12,654,951...12,665,143
Ensembl chr 1:12,654,838...12,665,207
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Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Zearalenone results in increased expression of ACACA mRNA |
CTD |
PMID:38159578 |
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NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
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Acat2 |
acetyl-CoA acetyltransferase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ACAT2 protein |
CTD |
PMID:25058043 |
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NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821
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Ackr2 |
atypical chemokine receptor 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ACKR2 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582
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Aco1 |
aconitase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ACO1 protein |
CTD |
PMID:36252740 |
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NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:55,259,827...55,316,391
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Acsf2 |
acyl-CoA synthetase family member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of ACSF2 protein |
CTD |
PMID:25058043 |
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NCBI chr10:80,001,389...80,043,796
Ensembl chr10:79,504,511...79,546,673
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Actr3 |
actin related protein 3 |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in increased expression of ACTR3 protein |
CTD |
PMID:25058043 |
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NCBI chr13:39,353,413...39,396,509
Ensembl chr13:36,800,093...36,844,124
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Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
increases expression decreases expression |
ISO EXP |
Zearalenone results in increased expression of ADAMTS9 mRNA Zearalenone results in decreased expression of ADAMTS9 mRNA |
CTD |
PMID:17557909 PMID:19371625 |
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NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:125,291,490...125,462,929
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Adh7 |
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
decreases expression |
ISO |
Zearalenone results in decreased expression of ADH7 protein |
CTD |
PMID:25058043 |
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NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:226,741,788...226,763,182
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Aff3 |
ALF transcription elongation factor 3 |
increases expression |
ISO |
Zearalenone results in increased expression of AFF3 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:40,404,375...40,857,247
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Agfg2 |
ArfGAP with FG repeats 2 |
increases expression |
ISO |
Zearalenone results in increased expression of AGFG2 protein |
CTD |
PMID:36252740 |
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NCBI chr12:19,012,228...19,048,433
Ensembl chr12:19,012,258...19,048,421
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Agt |
angiotensinogen |
increases expression |
ISO |
Zearalenone results in increased expression of AGT mRNA |
CTD |
PMID:36828454 |
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NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977
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Ahr |
aryl hydrocarbon receptor |
increases expression |
ISO |
Zearalenone results in increased expression of AHR mRNA |
CTD |
PMID:32119988 |
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NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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Ahsa1 |
activator of Hsp90 ATPase activity 1 |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in increased expression of AHSA1 protein |
CTD |
PMID:25058043 |
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NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
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Aicda |
activation-induced cytidine deaminase |
increases expression |
ISO |
Zearalenone results in increased expression of AICDA mRNA |
CTD |
PMID:27757495 |
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NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:155,774,132...155,783,972
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Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
increases expression |
ISO |
Zearalenone results in increased expression of AIFM1 protein |
CTD |
PMID:25058043 |
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NCBI chr X:132,528,107...132,567,237
Ensembl chr X:127,650,226...127,689,256
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Akr1b1 |
aldo-keto reductase family 1 member B1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of AKR1B1 protein |
CTD |
PMID:36252740 |
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NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157
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Akt1 |
AKT serine/threonine kinase 1 |
decreases expression increases expression decreases phosphorylation multiple interactions |
ISO EXP |
Zearalenone results in decreased expression of AKT1 protein Zearalenone results in increased expression of AKT1 mRNA Zearalenone results in decreased phosphorylation of AKT1 protein [Zearalenone co-treated with deoxynivalenol] results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:31419471 PMID:32119988 PMID:32858132 PMID:35090964 |
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NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
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Akt3 |
AKT serine/threonine kinase 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of AKT3 mRNA |
CTD |
PMID:30717214 |
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NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708
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Alad |
aminolevulinate dehydratase |
multiple interactions decreases activity |
ISO |
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein] |
CTD |
PMID:25682699 |
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NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:75,961,993...75,972,474
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Alb |
albumin |
affects expression multiple interactions decreases expression |
ISO |
Zearalenone affects the expression of ALB mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA Zearalenone results in decreased expression of ALB protein |
CTD |
PMID:28865950 PMID:28935499 PMID:34537261 |
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NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
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Aldob |
aldolase, fructose-bisphosphate B |
multiple interactions increases expression |
ISO |
[deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA Zearalenone results in increased expression of ALDOB mRNA |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116
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Aldoc |
aldolase, fructose-bisphosphate C |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of ALDOA protein; Zearalenone results in decreased expression of ALDOC protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of ALDOA protein] |
CTD |
PMID:25058043 PMID:38159578 |
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NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066
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Alpg |
alkaline phosphatase, germ cell |
increases expression |
ISO |
Zearalenone results in increased expression of ALPG mRNA |
CTD |
PMID:19371625 |
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NCBI chr 9:95,187,995...95,205,127
Ensembl chr 9:87,753,648...87,757,836
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Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions |
ISO |
[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein] |
CTD |
PMID:12650720 |
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NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446
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Anapc1 |
anaphase promoting complex subunit 1 |
increases expression |
ISO |
Zearalenone results in increased expression of ANAPC1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 3:136,303,350...136,383,464
Ensembl chr 3:115,850,185...115,930,273
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Ano1 |
anoctamin 1 |
increases expression |
ISO |
Zearalenone results in increased expression of ANO1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:199,751,439...199,900,069
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Anp32a |
acidic nuclear phosphoprotein 32 family member A |
decreases expression |
ISO |
Zearalenone results in decreased expression of ANP32A protein |
CTD |
PMID:36252740 |
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NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:62,827,456...62,865,443
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Anp32b |
acidic nuclear phosphoprotein 32 family member B |
decreases expression |
ISO |
Zearalenone results in decreased expression of ANP32B protein |
CTD |
PMID:36252740 |
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NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
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Anp32e |
acidic nuclear phosphoprotein 32 family member E |
decreases expression |
ISO |
Zearalenone results in decreased expression of ANP32E protein |
CTD |
PMID:36252740 |
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NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:183,472,609...183,489,054
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Anxa3 |
annexin A3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ANXA3 protein |
CTD |
PMID:25058043 |
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NCBI chr14:13,031,675...13,085,678
Ensembl chr14:12,719,795...12,781,617
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Anxa5 |
annexin A5 |
affects binding |
ISO |
Zearalenone binds to ANXA5 protein |
CTD |
PMID:24412631 |
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NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:119,314,007...119,353,369
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Anxa7 |
annexin A7 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ANXA7 protein |
CTD |
PMID:25058043 |
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NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,821,845...3,849,385
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Apaf1 |
apoptotic peptidase activating factor 1 |
increases expression |
ISO |
Zearalenone results in increased expression of APAF1 mRNA |
CTD |
PMID:34537261 |
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NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540
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Apln |
apelin |
decreases expression |
EXP |
Zearalenone results in decreased expression of APLN mRNA |
CTD |
PMID:17557909 |
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NCBI chr X:132,058,739...132,091,518
Ensembl chr X:127,203,823...127,213,391
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Apobec1 |
apolipoprotein B mRNA editing enzyme catalytic subunit 1 |
increases expression |
EXP |
Zearalenone results in increased expression of APOBEC1 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 4:157,472,879...157,500,496
Ensembl chr 4:155,800,887...155,827,390
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Apoe |
apolipoprotein E |
decreases expression |
ISO |
Zearalenone results in decreased expression of APOE mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
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Aprt |
adenine phosphoribosyl transferase |
decreases expression |
ISO |
Zearalenone results in decreased expression of APRT protein |
CTD |
PMID:36252740 |
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NCBI chr19:67,534,737...67,537,027
Ensembl chr19:50,626,202...50,628,431
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Aqp5 |
aquaporin 5 |
increases expression |
ISO |
Zearalenone results in increased expression of AQP5 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:130,721,748...130,726,209
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Ar |
androgen receptor |
multiple interactions decreases expression decreases activity |
ISO |
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; Zearalenone inhibits the reaction [Metribolone results in increased activity of AR protein]; Zearalenone inhibits the reaction [Testosterone binds to and results in increased activity of AR protein] Zearalenone results in decreased expression of AR mRNA Zearalenone metabolite results in decreased activity of AR protein; Zearalenone results in decreased activity of AR protein |
CTD |
PMID:18324785 PMID:21803136 PMID:24412631 PMID:25455890 PMID:27481073 |
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NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925
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Arhgap26 |
Rho GTPase activating protein 26 |
increases expression |
ISO |
Zearalenone results in increased expression of ARHGAP26 mRNA |
CTD |
PMID:36828454 |
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NCBI chr18:30,702,602...31,489,047
Ensembl chr18:30,838,671...31,235,194
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Arnt |
aryl hydrocarbon receptor nuclear translocator |
increases expression |
EXP |
Zearalenone results in increased expression of ARNT mRNA |
CTD |
PMID:20607812 |
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NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:182,997,736...183,056,580
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As3mt |
arsenite methyltransferase |
decreases expression |
ISO |
Zearalenone results in decreased expression of AS3MT protein |
CTD |
PMID:36252740 |
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NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
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Asah1 |
N-acylsphingosine amidohydrolase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ASAH1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr16:57,669,927...57,701,349
Ensembl chr16:50,966,229...51,008,233
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Asrgl1 |
asparaginase and isoaspartyl peptidase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of ASRGL1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:206,006,103...206,027,115
Ensembl chr 1:206,006,109...206,027,108
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Atg5 |
autophagy related 5 |
increases expression |
ISO |
Zearalenone results in increased expression of ATG5 mRNA; Zearalenone results in increased expression of ATG5 protein |
CTD |
PMID:34537261 |
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NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
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Atic |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
decreases expression |
ISO |
Zearalenone results in decreased expression of ATIC protein |
CTD |
PMID:36252740 |
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NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:73,164,846...73,184,889
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Atm |
ATM serine/threonine kinase |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of ATM mRNA Zearalenone results in decreased expression of ATM mRNA; Zearalenone results in decreased expression of ATM protein |
CTD |
PMID:27862621 PMID:29758222 |
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NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437
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Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of ATP1A1 protein |
CTD |
PMID:25058043 |
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NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:189,020,722...189,048,837
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Atp5pb |
ATP synthase peripheral stalk-membrane subunit b |
increases expression |
ISO |
Zearalenone results in increased expression of ATP5PB protein |
CTD |
PMID:25058043 |
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NCBI chr 2:196,112,459...196,123,737
Ensembl chr 2:193,424,047...193,435,418
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Atpaf1 |
ATP synthase mitochondrial F1 complex assembly factor 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ATPAF1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 5:129,265,789...129,292,463
Ensembl chr 5:129,266,404...129,293,556
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Bax |
BCL2 associated X, apoptosis regulator |
affects localization increases expression multiple interactions |
ISO EXP |
Zearalenone affects the localization of BAX protein Zearalenone results in increased expression of BAX mRNA; Zearalenone results in increased expression of BAX protein Zearalenone results in increased expression of BAX; Zearalenone results in increased expression of BAX mRNA; Zearalenone results in increased expression of BAX protein Aflatoxin B1 inhibits the reaction [Zearalenone results in increased expression of BAX mRNA]; crocin inhibits the reaction [Zearalenone results in increased expression of BAX protein]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA] [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX protein |
CTD |
PMID:19541794 PMID:21767629 PMID:24530352 PMID:25445755 PMID:26231423 PMID:28089945 PMID:30600648 PMID:32858132 PMID:34537261 PMID:35090964 PMID:36288102 More...
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NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
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Bcl2 |
BCL2, apoptosis regulator |
decreases expression increases expression multiple interactions |
ISO EXP |
Zearalenone results in decreased expression of BCL2 mRNA; Zearalenone results in decreased expression of BCL2 protein Zearalenone results in increased expression of BCL2 mRNA crocin inhibits the reaction [Zearalenone results in decreased expression of BCL2 protein] |
CTD |
PMID:21767629 PMID:24412631 PMID:26231423 PMID:28089945 PMID:28965971 PMID:30600648 PMID:32858132 PMID:36288102 More...
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of BDNF mRNA |
CTD |
PMID:24412706 |
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NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615
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Becn1 |
beclin 1 |
increases expression multiple interactions |
EXP ISO |
Zearalenone results in increased expression of BECN1; Zearalenone results in increased expression of BECN1 protein acadesine promotes the reaction [Zearalenone results in increased expression of BECN1 protein] |
CTD |
PMID:24530352 PMID:31982503 PMID:32858132 |
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NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742
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Bend3 |
BEN domain containing 3 |
increases expression |
ISO |
Zearalenone results in increased expression of BEND3 mRNA |
CTD |
PMID:36828454 |
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NCBI chr20:48,562,383...48,599,194
Ensembl chr20:46,979,831...47,014,671
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Bfar |
bifunctional apoptosis regulator |
increases expression |
ISO |
Zearalenone results in increased expression of BFAR protein |
CTD |
PMID:36252740 |
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NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038
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Bicd1 |
BICD cargo adaptor 1 |
increases expression |
ISO |
Zearalenone results in increased expression of BICD1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:182,479,071...182,627,434
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G |
Bid |
BH3 interacting domain death agonist |
increases activity multiple interactions |
EXP |
Zearalenone results in increased activity of BID protein benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased activity of BID protein] |
CTD |
PMID:30600648 |
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NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720
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Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Zearalenone results in increased expression of BIRC5 mRNA |
CTD |
PMID:28965971 |
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NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380
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Blnk |
B-cell linker |
decreases expression |
ISO |
Zearalenone results in decreased expression of BLNK mRNA |
CTD |
PMID:36828454 |
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NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:239,753,648...239,821,113
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G |
Bmf |
Bcl2 modifying factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of BMF mRNA |
CTD |
PMID:36828454 |
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NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:105,499,538...105,520,145
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G |
Bmp3 |
bone morphogenetic protein 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of BMP3 mRNA |
CTD |
PMID:36828454 |
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NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
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Bnip1 |
BCL2 interacting protein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of BNIP1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr10:16,891,317...16,903,561
Ensembl chr10:16,386,841...16,399,157
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Bola2 |
bolA family member 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of BOLA2 protein |
CTD |
PMID:36252740 |
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NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676
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Braf |
B-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Zearalenone results in increased expression of BRAF protein |
CTD |
PMID:29758222 |
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NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463
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Brca1 |
BRCA1, DNA repair associated |
increases expression |
ISO |
Zearalenone results in increased expression of BRCA1 mRNA |
CTD |
PMID:28552778 PMID:28965971 |
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NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304
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Bud31 |
BUD31 homolog |
increases expression |
ISO |
Zearalenone results in increased expression of BUD31 protein |
CTD |
PMID:36252740 |
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NCBI chr12:14,576,602...14,584,132
Ensembl chr12:9,462,441...9,470,509
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C1galt1c1 |
C1GALT1-specific chaperone 1 |
increases expression |
ISO |
Zearalenone results in increased expression of C1GALT1C1 protein |
CTD |
PMID:36252740 |
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NCBI chr X:122,243,736...122,248,217
Ensembl chr X:117,375,525...117,382,787
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C3 |
complement C3 |
increases expression |
EXP |
Zearalenone results in increased expression of C3 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429
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Cables1 |
Cdk5 and Abl enzyme substrate 1 |
increases expression |
ISO |
Zearalenone results in increased expression of CABLES1 mRNA |
CTD |
PMID:19371625 PMID:36828454 |
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NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,075,524...3,181,181
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Cadm1 |
cell adhesion molecule 1 |
increases expression |
ISO |
Zearalenone results in increased expression of CADM1 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:47,847,325...48,182,833
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Calr |
calreticulin |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of CALR protein |
CTD |
PMID:25058043 |
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NCBI chr19:40,213,367...40,218,262
Ensembl chr19:23,308,351...23,313,414
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Camkk2 |
calcium/calmodulin-dependent protein kinase kinase 2 |
increases phosphorylation multiple interactions |
ISO |
Zearalenone results in increased phosphorylation of CAMKK2 protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased phosphorylation of CAMKK2 protein]; STO 609 inhibits the reaction [Zearalenone results in increased phosphorylation of CAMKK2 protein] |
CTD |
PMID:31982503 |
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NCBI chr12:39,451,828...39,505,719
Ensembl chr12:33,791,052...33,843,279
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Capn9 |
calpain 9 |
increases expression |
ISO |
Zearalenone results in increased expression of CAPN9 mRNA |
CTD |
PMID:19371625 |
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NCBI chr19:52,549,448...52,586,413
Ensembl chr19:52,549,448...52,586,413
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Car12 |
carbonic anhydrase 12 |
increases expression |
ISO |
Zearalenone results in increased expression of CA12 mRNA |
CTD |
PMID:33419253 PMID:36828454 |
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NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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Car2 |
carbonic anhydrase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of CA2 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818
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G |
Carhsp1 |
calcium regulated heat stable protein 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CARHSP1 protein |
CTD |
PMID:36252740 |
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NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
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G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of CARS1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:198,753,691...198,795,941
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Casp1 |
caspase 1 |
increases expression multiple interactions |
ISO EXP |
Zearalenone results in increased expression of CASP1 mRNA; Zearalenone results in increased expression of CASP1 protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein Zearalenone results in increased expression of CASP1 protein modified form 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form] |
CTD |
PMID:30270565 PMID:31586597 |
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NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383
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Casp3 |
caspase 3 |
increases activity multiple interactions increases expression increases cleavage decreases expression |
ISO EXP |
Zearalenone results in increased activity of CASP3 protein HERPUD1 protein promotes the reaction [Zearalenone results in increased expression of CASP3 protein modified form]; RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]; scutellarin affects the reaction [RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]]; scutellarin inhibits the reaction [Zearalenone results in increased cleavage of CASP3 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA] Zearalenone results in increased expression of CASP3 mRNA; Zearalenone results in increased expression of CASP3 protein modified form [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; [Zearalenone co-treated with deoxynivalenol] results in increased expression of CASP3 protein benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased cleavage of CASP3 protein]; Zearalenone results in decreased expression of and results in increased cleavage of CASP3 protein Zearalenone results in decreased expression of CASP3 protein |
CTD |
PMID:19541794 PMID:19705349 PMID:24530352 PMID:25445755 PMID:28089945 PMID:30394307 PMID:30600648 PMID:30668976 PMID:32858132 PMID:34537261 PMID:35090964 PMID:36252740 PMID:36288102 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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Casp8 |
caspase 8 |
increases expression multiple interactions increases cleavage |
ISO EXP |
Zearalenone results in increased expression of CASP8 mRNA [Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA] Zearalenone results in increased cleavage of CASP8 protein |
CTD |
PMID:30600648 PMID:30668976 |
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NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity multiple interactions increases expression increases cleavage |
EXP ISO |
Zearalenone results in increased activity of CASP9 protein Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA] Zearalenone results in increased expression of CASP9 mRNA Zearalenone results in increased cleavage of CASP9 protein benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Zearalenone results in increased cleavage of CASP9 protein] Zearalenone results in increased expression of CASP9 protein modified form |
CTD |
PMID:24530352 PMID:30600648 PMID:30668976 PMID:34537261 PMID:36288102 |
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Ensembl chr 5:154,109,046...154,126,626
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Cat |
catalase |
increases expression decreases expression multiple interactions decreases activity increases activity |
ISO EXP |
Zearalenone results in increased expression of CAT mRNA Zearalenone results in decreased expression of CAT protein Zearalenone results in decreased expression of CAT mRNA; Zearalenone results in decreased expression of CAT protein Gallic Acid inhibits the reaction [Zearalenone results in decreased activity of CAT protein] Zearalenone results in increased activity of CAT protein [Nicotinamide Mononucleotide co-treated with Zearalenone] results in decreased expression of CAT protein; crocin inhibits the reaction [Zearalenone results in increased activity of CAT protein] |
CTD |
PMID:26231423 PMID:28089945 PMID:28477956 PMID:32858132 PMID:34723416 PMID:38159578 More...
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cbfa2t3 |
CBFA2/RUNX1 partner transcriptional co-repressor 3 |
increases expression |
ISO |
Zearalenone results in increased expression of CBFA2T3 mRNA |
CTD |
PMID:19371625 |
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NCBI chr19:67,584,319...67,658,533
Ensembl chr19:50,680,729...50,749,610
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G |
Cbln1 |
cerebellin 1 precursor |
increases expression |
ISO |
Zearalenone results in increased expression of CBLN1 mRNA |
CTD |
PMID:36828454 |
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NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572
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G |
Cbr1 |
carbonyl reductase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CBR1 protein |
CTD |
PMID:36252740 |
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NCBI chr11:46,346,405...46,348,815
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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Ccl21 |
C-C motif chemokine ligand 21 |
increases expression |
ISO |
Zearalenone results in increased expression of CCL21 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:56,980,558...56,981,686
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
ISO |
Zearalenone results in increased expression of CCL22 mRNA |
CTD |
PMID:27757495 |
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NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,257,601...10,264,400
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G |
Ccn5 |
cellular communication network factor 5 |
increases expression |
ISO |
Zearalenone results in increased expression of CCN5 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:152,491,220...152,502,636
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G |
Ccna1 |
cyclin A1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CCNA1 mRNA |
CTD |
PMID:24412631 |
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NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CCNB1 mRNA; Zearalenone results in decreased expression of CCNB1 protein |
CTD |
PMID:27862621 PMID:35504548 |
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NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions increases expression |
ISO EXP |
Zearalenone results in decreased expression of CCND1 mRNA [Tamoxifen co-treated with Zearalenone] results in increased expression of CCND1 protein Zearalenone results in increased expression of CCND1 mRNA; Zearalenone results in increased expression of CCND1 protein Zearalenone results in decreased expression of CCND1 protein |
CTD |
PMID:24412631 PMID:27473017 PMID:30138655 PMID:36288102 |
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NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
decreases expression |
EXP ISO |
Zearalenone results in decreased expression of CCND2 mRNA |
CTD |
PMID:17557909 PMID:28965971 |
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NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO |
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of CCNE1 mRNA |
CTD |
PMID:28965971 |
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NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccr1 |
C-C motif chemokine receptor 1 |
increases expression |
ISO |
Zearalenone results in increased expression of CCR1 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 8:132,433,711...132,439,266
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G |
Ccr4 |
C-C motif chemokine receptor 4 |
increases expression |
ISO |
Zearalenone results in increased expression of CCR4 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:114,176,974...114,178,056
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G |
Cct2 |
chaperonin containing TCP1 subunit 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CCT2 protein |
CTD |
PMID:36252740 |
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NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of CCT5 protein Zearalenone results in decreased expression of CCT5 protein |
CTD |
PMID:25058043 PMID:36252740 |
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NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
Zearalenone results in increased expression of CD274 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450
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G |
Cd36 |
CD36 molecule |
multiple interactions decreases expression increases expression |
ISO EXP |
[Zearalenone co-treated with CGA protein] results in decreased expression of CD36 protein; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CD36 mRNA] Zearalenone results in decreased expression of CD36 mRNA; Zearalenone results in decreased expression of CD36 protein |
CTD |
PMID:25058043 PMID:32858132 PMID:38159578 |
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NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd38 |
CD38 molecule |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of CD38 mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CD38 mRNA] |
CTD |
PMID:38159578 |
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NCBI chr14:71,384,532...71,424,794
Ensembl chr14:67,172,063...67,211,986
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G |
Cd86 |
CD86 molecule |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Zearalenone] results in increased expression of CD86 protein |
CTD |
PMID:32328699 |
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NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818
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G |
Cdc25c |
cell division cycle 25C |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDC25C protein |
CTD |
PMID:35504548 |
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NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185
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G |
Cdc6 |
cell division cycle 6 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDC6 mRNA |
CTD |
PMID:27862621 |
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NCBI chr10:84,360,361...84,374,239
Ensembl chr10:83,864,638...83,878,011
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G |
Cdca7 |
cell division cycle associated 7 |
increases expression |
ISO |
Zearalenone results in increased expression of CDCA7 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDH1 mRNA |
CTD |
PMID:33419253 |
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NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDK1 protein |
CTD |
PMID:34716709 PMID:35504548 |
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NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk4 |
cyclin-dependent kinase 4 |
increases expression |
ISO |
Zearalenone results in increased expression of CDK4 protein |
CTD |
PMID:27473017 |
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NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDKN1A mRNA |
CTD |
PMID:24412631 |
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDKN1C mRNA |
CTD |
PMID:28965971 |
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NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
decreases expression |
ISO |
Zearalenone results in decreased expression of CDKN2A mRNA |
CTD |
PMID:28965971 |
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NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
affects expression multiple interactions |
ISO |
Zearalenone affects the expression of CEBPA mRNA [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA |
CTD |
PMID:28865950 |
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NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
Zearalenone results in increased expression of CEBPB mRNA |
CTD |
PMID:25424538 |
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NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
increases expression |
ISO |
Zearalenone results in increased expression of CEBPD mRNA |
CTD |
PMID:19371625 |
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NCBI chr11:98,268,856...98,269,994
Ensembl chr11:84,764,565...84,765,829
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G |
Cfap99 |
cilia and flagella associated protein 99 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CFAP99 protein |
CTD |
PMID:36252740 |
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NCBI chr14:76,423,923...76,468,170
Ensembl chr14:76,410,555...76,468,125
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G |
Cfi |
complement factor I |
increases expression |
EXP |
Zearalenone results in increased expression of CFI mRNA |
CTD |
PMID:17557909 |
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NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:218,387,990...218,430,561
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions increases expression |
ISO |
fulvestrant inhibits the reaction [Zearalenone results in increased expression of CGA protein] [Zearalenone co-treated with CGA protein] results in decreased expression of ATP1A1 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of CALR protein; [Zearalenone co-treated with CGA protein] results in decreased expression of CD36 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of HSD17B11 protein; [Zearalenone co-treated with CGA protein] results in decreased expression of MGLL protein; [Zearalenone co-treated with CGA protein] results in decreased expression of P4HB protein; [Zearalenone co-treated with CGA protein] results in decreased expression of SMPDL3B protein; [Zearalenone co-treated with CGA protein] results in decreased expression of SYAP1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of ACTR3 protein; [Zearalenone co-treated with CGA protein] results in increased expression of AHSA1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of DNM1L protein; [Zearalenone co-treated with CGA protein] results in increased expression of PDCD6IP protein; [Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein; [Zearalenone co-treated with CGA protein] results in increased expression of TLN1 protein; [Zearalenone co-treated with CGA protein] results in increased expression of YKT6 protein |
CTD |
PMID:19580841 PMID:25058043 |
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NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of CHAC1 mRNA |
CTD |
PMID:25424538 |
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NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526
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G |
Chac2 |
ChaC glutathione specific gamma-glutamylcyclotransferase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of CHAC2 mRNA |
CTD |
PMID:19371625 |
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NCBI chr14:108,921,669...108,929,215
Ensembl chr14:104,720,758...104,728,301
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G |
Chchd3 |
coiled-coil-helix-coiled-coil-helix domain containing 3 |
increases expression |
ISO |
Zearalenone results in increased expression of CHCHD3 protein |
CTD |
PMID:25058043 |
|
NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
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G |
Chek1 |
checkpoint kinase 1 |
increases expression decreases phosphorylation |
ISO |
Zearalenone results in increased expression of CHEK1 protein Zearalenone results in decreased phosphorylation of CHK1 protein |
CTD |
PMID:34716709 PMID:35504548 |
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NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:36,420,569...36,441,009
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G |
Chek2 |
checkpoint kinase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CHEK2 protein |
CTD |
PMID:35504548 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286
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G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CHORDC1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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G |
Cish |
cytokine inducible SH2-containing protein |
increases expression |
ISO |
Zearalenone results in increased expression of CISH mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
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G |
Ckb |
creatine kinase B |
decreases expression |
ISO |
Zearalenone results in decreased expression of CKB protein |
CTD |
PMID:36252740 |
|
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:130,729,423...130,732,315
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G |
Cldn1 |
claudin 1 |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of CLDN1 protein [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr11:87,926,376...87,941,533
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn8 |
claudin 8 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CLDN8 mRNA |
CTD |
PMID:36828454 |
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NCBI chr11:41,362,081...41,364,330
Ensembl chr11:27,875,692...27,878,513
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G |
Cnfn |
cornifelin |
decreases expression |
ISO |
Zearalenone results in decreased expression of CNFN mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747
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G |
Cnn3 |
calponin 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CNN3 protein |
CTD |
PMID:36252740 |
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NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
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G |
Coa5 |
cytochrome C oxidase assembly factor 5 |
increases expression |
ISO |
Zearalenone results in increased expression of COA5 protein |
CTD |
PMID:36252740 |
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NCBI chr 9:39,651,459...39,664,870
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G |
Cops8 |
COP9 signalosome subunit 8 |
decreases expression |
ISO |
Zearalenone results in decreased expression of COPS8 protein |
CTD |
PMID:36252740 |
|
NCBI chr 9:98,655,031...98,664,861
Ensembl chr 9:91,207,395...91,217,258
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G |
Coro1c |
coronin 1C |
increases expression |
ISO |
Zearalenone results in increased expression of CORO1C mRNA |
CTD |
PMID:19371625 |
|
NCBI chr12:48,373,573...48,445,718
Ensembl chr12:42,712,991...42,785,179
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of CPT1A mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CPT1A mRNA] |
CTD |
PMID:38159578 |
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NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of CPT2 protein |
CTD |
PMID:25058043 PMID:36252740 |
|
NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
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G |
Crabp2 |
cellular retinoic acid binding protein 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CRABP2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:173,416,857...173,421,379
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G |
Crybg2 |
crystallin beta-gamma domain containing 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CRYBG2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:146,286,925...146,323,666
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G |
Cse1l |
chromosome segregation 1 like |
decreases expression |
ISO |
Zearalenone results in decreased expression of CSE1L protein |
CTD |
PMID:36252740 |
|
NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
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G |
Csf2 |
colony stimulating factor 2 |
increases expression |
ISO |
Zearalenone results in increased expression of CSF2 mRNA |
CTD |
PMID:27757495 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199
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G |
Cst6 |
cystatin E/M |
decreases expression |
ISO |
Zearalenone results in decreased expression of CST6 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:202,655,322...202,657,030
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G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
increases expression |
ISO |
Zearalenone results in increased expression of CTLA4 mRNA |
CTD |
PMID:27757495 |
|
NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963
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G |
Ctnnb1 |
catenin beta 1 |
decreases expression |
EXP ISO |
Zearalenone results in decreased expression of CTNNB1 protein |
CTD |
PMID:36288102 |
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NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsd |
cathepsin D |
increases expression |
ISO |
Zearalenone results in increased expression of CTSD mRNA |
CTD |
PMID:28965971 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
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G |
Cuta |
cutA divalent cation tolerance homolog |
decreases expression |
ISO |
Zearalenone results in decreased expression of CUTA mRNA |
CTD |
PMID:19371625 |
|
NCBI chr20:5,024,816...5,026,446
Ensembl chr20:5,022,956...5,024,552
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G |
Cux1 |
cut-like homeobox 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CUX1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr12:25,728,393...26,062,497
Ensembl chr12:20,107,311...20,425,866 Ensembl chr 4:20,107,311...20,425,866
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G |
Cuzd1 |
CUB and zona pellucida-like domains 1 |
increases expression |
EXP |
Zearalenone results in increased expression of CUZD1 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 1:186,089,422...186,130,536
Ensembl chr 1:186,089,423...186,102,546
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Zearalenone results in increased expression of CXCL12 mRNA |
CTD |
PMID:27757495 PMID:28396216 |
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NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Zearalenone results in increased expression of CXCL9 mRNA |
CTD |
PMID:27757495 |
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NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr5 |
C-X-C motif chemokine receptor 5 |
increases expression |
ISO |
Zearalenone results in increased expression of CXCR5 mRNA |
CTD |
PMID:27757495 |
|
NCBI chr 8:53,738,878...53,756,813
Ensembl chr 8:44,843,413...44,857,893
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G |
Cycs |
cytochrome c, somatic |
affects localization increases expression |
ISO |
Zearalenone affects the localization of CYCS protein Zearalenone results in increased expression of CYCS protein |
CTD |
PMID:19541794 PMID:25058043 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression multiple interactions decreases activity |
ISO EXP |
Zearalenone results in decreased expression of CYP11A1 mRNA; Zearalenone results in decreased expression of CYP11A1 protein [Colforsin co-treated with Zearalenone] results in increased expression of CYP11A1 mRNA Zearalenone results in decreased activity of CYP11A1 protein |
CTD |
PMID:24512812 PMID:26783879 PMID:29669061 PMID:31419471 |
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NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression |
ISO EXP |
Zearalenone results in decreased expression of CYP17A1 mRNA |
CTD |
PMID:24512812 PMID:32858132 |
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NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases activity decreases expression |
ISO |
Zearalenone results in decreased activity of CYP19A1 protein Zearalenone results in decreased expression of CYP19A1 mRNA; Zearalenone results in decreased expression of CYP19A1 protein |
CTD |
PMID:16023337 PMID:29758222 PMID:36374910 |
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NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions decreases activity decreases expression |
ISO |
Tamoxifen inhibits the reaction [Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]; Tamoxifen inhibits the reaction [Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Zearalenone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Zearalenone results in decreased activity of CYP1A1 protein Zearalenone results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:15157572 PMID:34181028 |
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NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases hydroxylation multiple interactions decreases activity decreases abundance |
ISO |
CYP1A2 protein results in increased hydroxylation of Zearalenone [CYP1A2 protein results in increased hydroxylation of Zearalenone] which results in increased chemical synthesis of Catechols Zearalenone results in decreased activity of CYP1A2 protein CYP1A2 protein results in decreased abundance of Zearalenone |
CTD |
PMID:19931366 PMID:38341109 |
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NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases activity multiple interactions |
ISO |
Zearalenone results in increased activity of CYP1B1 protein Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] |
CTD |
PMID:15157572 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2c7 |
cytochrome P450, family 2, subfamily c, polypeptide 7 |
increases expression |
EXP |
Zearalenone results in increased expression of CYP2C7 mRNA |
CTD |
PMID:20607812 |
|
NCBI chr 1:247,966,295...248,022,393
Ensembl chr 1:237,332,659...237,388,709
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases expression |
EXP |
Zearalenone results in increased expression of CYP2E1 mRNA |
CTD |
PMID:20607812 |
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NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases expression multiple interactions decreases abundance decreases activity |
EXP ISO |
Zearalenone results in increased expression of CYP3A2 mRNA Zearalenone results in increased expression of CYP3A4 mRNA; Zearalenone results in increased expression of CYP3A4 protein [deoxynivalenol co-treated with Zearalenone] affects the expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP3A4 protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 protein; Zearalenone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4] CYP3A4 protein results in decreased abundance of Zearalenone Zearalenone results in decreased activity of CYP3A4 protein |
CTD |
PMID:15569515 PMID:20607812 PMID:28865950 PMID:28935499 PMID:36893891 PMID:38341109 More...
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NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
increases expression |
EXP |
Zearalenone results in increased expression of CYP3A23-3A1 mRNA |
CTD |
PMID:20607812 |
|
NCBI chr12:14,369,950...14,398,803
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
multiple interactions decreases expression |
ISO |
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA Zearalenone results in decreased expression of CYP4F3 mRNA |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,707,317...17,804,940
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
Zearalenone results in increased expression of CYP51 protein |
CTD |
PMID:25058043 |
|
NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,036,865...30,055,410 Ensembl chr 6:30,036,865...30,055,410
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G |
Cysrt1 |
cysteine rich tail 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of CYSRT1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:28,452,359...28,456,006
Ensembl chr 3:8,053,482...8,059,721
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G |
Dars1 |
aspartyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of DARS1 protein |
CTD |
PMID:25058043 |
|
NCBI chr13:42,410,351...42,465,467
Ensembl chr13:39,857,936...39,913,116
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G |
Dazl |
deleted in azoospermia-like |
decreases expression |
ISO |
Zearalenone results in decreased expression of DAZL mRNA; Zearalenone results in decreased expression of DAZL protein |
CTD |
PMID:28552778 PMID:31419471 |
|
NCBI chr 9:18,193,363...18,210,100
Ensembl chr 9:10,695,592...10,712,323
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G |
Ddc |
dopa decarboxylase |
decreases expression |
ISO |
Zearalenone results in decreased expression of DDC mRNA |
CTD |
PMID:24412706 |
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NCBI chr14:90,592,304...90,682,830
Ensembl chr14:86,378,685...86,469,208
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of DDIT3 protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased expression of DDIT3 protein]; 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of DDIT3 protein] |
CTD |
PMID:30394307 PMID:31982503 |
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NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
decreases expression |
ISO |
Zearalenone results in decreased expression of DDIT4L mRNA |
CTD |
PMID:36828454 |
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NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:226,128,276...226,131,375
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G |
Ddx25 |
DEAD-box helicase 25 |
decreases expression |
ISO |
Zearalenone results in decreased expression of DDX25 mRNA |
CTD |
PMID:24412631 |
|
NCBI chr 8:42,152,046...42,168,635
Ensembl chr 8:33,894,232...33,921,764
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G |
Ddx4 |
DEAD-box helicase 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of DDX4 protein; Zearalenone results in decreased expression of VASA protein |
CTD |
PMID:28089945 PMID:31419471 |
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NCBI chr 2:45,961,174...46,016,097
Ensembl chr 2:44,227,946...44,282,723
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G |
Deptor |
DEP domain containing MTOR-interacting protein |
increases expression |
ISO |
Zearalenone results in increased expression of DEPTOR mRNA |
CTD |
PMID:33419253 PMID:36828454 |
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NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:86,514,988...86,667,773
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions increases expression |
ISO |
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of DGAT1 mRNA] |
CTD |
PMID:38159578 |
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NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions increases expression |
ISO |
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of DGAT2 mRNA] |
CTD |
PMID:38159578 |
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NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:153,454,080...153,484,428
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G |
Dhrs2 |
dehydrogenase/reductase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of DHRS2 mRNA |
CTD |
PMID:36828454 |
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NCBI chr15:32,658,855...32,673,591
Ensembl chr15:28,688,940...28,703,644
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G |
Dhrs3 |
dehydrogenase/reductase 3 |
increases expression |
ISO |
Zearalenone results in increased expression of DHRS3 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:156,747,962...156,782,417
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G |
Dio3os |
DIO3 opposite strand upstream RNA |
decreases expression |
ISO |
Zearalenone results in decreased expression of DIO3OS mRNA |
CTD |
PMID:30790392 |
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Diras3 |
DIRAS family GTPase 3 |
increases expression |
ISO |
Zearalenone results in increased expression of DIRAS3 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 6:130,524,972...130,526,186
Ensembl chr 6:130,524,742...130,530,825
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of DKK2 mRNA |
CTD |
PMID:27862621 |
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NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
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G |
Dld |
dihydrolipoamide dehydrogenase |
increases expression |
ISO |
Zearalenone results in increased expression of DLD protein |
CTD |
PMID:25058043 |
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NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:47,903,914...47,924,795
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
increases expression |
EXP |
Zearalenone results in increased expression of DMBT1 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:185,617,294...185,696,478
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in increased expression of DNM1L protein |
CTD |
PMID:25058043 |
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NCBI chr11:98,084,049...98,135,663
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of DNMT1 mRNA |
CTD |
PMID:32119988 |
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659
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G |
Dohh |
deoxyhypusine hydroxylase |
decreases expression |
ISO |
Zearalenone results in decreased expression of DOHH protein |
CTD |
PMID:36252740 |
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NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289
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G |
Dok4 |
docking protein 4 |
increases expression |
ISO |
Zearalenone results in increased expression of DOK4 mRNA |
CTD |
PMID:19371625 |
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NCBI chr19:10,152,511...10,163,182
Ensembl chr19:10,146,474...10,158,203
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G |
Dpysl2 |
dihydropyrimidinase-like 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of DPYSL2 protein |
CTD |
PMID:25058043 |
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NCBI chr15:45,181,041...45,287,065
Ensembl chr15:41,005,551...41,111,829
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G |
Dstn |
destrin, actin depolymerizing factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of DSTN protein |
CTD |
PMID:36252740 |
|
NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:131,284,648...131,311,379
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G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of DUSP2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:114,556,325...114,558,499
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G |
Dvl1 |
dishevelled segment polarity protein 1 |
increases expression |
EXP |
Zearalenone results in increased expression of DVL1 mRNA |
CTD |
PMID:32858132 |
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NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:166,456,686...166,468,664
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G |
Dync1li2 |
dynein, cytoplasmic 1 light intermediate chain 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of DYNC1LI2 protein |
CTD |
PMID:36252740 |
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NCBI chr19:538,207...561,110
Ensembl chr19:531,812...554,670
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G |
Ece2 |
endothelin-converting enzyme 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ECE2 protein |
CTD |
PMID:36252740 |
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NCBI chr11:93,767,559...93,782,896
Ensembl chr11:80,263,162...80,278,428
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G |
Ech1 |
enoyl-CoA hydratase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ECH1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:84,112,751...84,120,795
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of ECHS1 mRNA; Zearalenone results in decreased expression of ECHS1 protein |
CTD |
PMID:32858132 |
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NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884
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G |
Eef1b2 |
eukaryotic translation elongation factor 1 beta 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of EEF1B2 protein |
CTD |
PMID:36252740 |
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NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:64,579,893...64,582,737
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G |
Efl1 |
elongation factor like GTPase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of EFL1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:136,638,527...136,763,518
Ensembl chr 1:136,638,527...136,763,518
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G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
Zearalenone results in increased expression of EGR1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of EHMT2 mRNA |
CTD |
PMID:32119988 |
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NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547
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G |
Eif1ax |
eukaryotic translation initiation factor 1A, X-linked |
decreases expression |
ISO |
Zearalenone results in decreased expression of EIF1AX protein |
CTD |
PMID:36252740 |
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NCBI chr X:39,307,320...39,322,023
Ensembl chr X:35,498,517...35,513,335
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
decreases phosphorylation |
EXP |
Zearalenone results in decreased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:32858132 |
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NCBI chr16:71,495,457...71,508,845
Ensembl chr16:64,790,226...64,805,984
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G |
Elovl3 |
ELOVL fatty acid elongase 3 |
multiple interactions increases expression |
ISO |
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of ELOVL3 mRNA] |
CTD |
PMID:38159578 |
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NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
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G |
Ep300 |
E1A binding protein p300 |
decreases expression |
EXP |
Zearalenone results in decreased expression of EP300 protein |
CTD |
PMID:36288102 |
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NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epas1 |
endothelial PAS domain protein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of EPAS1 mRNA |
CTD |
PMID:30138655 |
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NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228
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G |
Epb41l2 |
erythrocyte membrane protein band 4.1-like 2 |
increases expression |
ISO |
Zearalenone results in increased expression of EPB41L2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:19,863,009...20,037,721
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G |
Ephb3 |
Eph receptor B3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of EPHB3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr11:93,345,098...93,363,775
Ensembl chr11:79,840,668...79,859,370
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G |
Ephb4 |
EPH receptor B4 |
increases expression |
ISO |
Zearalenone results in increased expression of EPHB4 protein |
CTD |
PMID:36252740 |
|
NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314
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G |
Epn3 |
epsin 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of EPN3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ERBB3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525
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G |
Ercc3 |
ERCC excision repair 3, TFIIH core complex helicase subunit |
increases expression |
ISO |
Zearalenone results in increased expression of ERCC3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr18:24,157,831...24,188,543
Ensembl chr18:23,883,580...23,914,329
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G |
Erg |
ETS transcription factor ERG |
increases expression |
ISO |
Zearalenone results in increased expression of ERG mRNA |
CTD |
PMID:36828454 |
|
NCBI chr11:48,148,149...48,370,472
Ensembl chr11:34,678,618...34,845,871
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G |
Erich3 |
glutamate-rich 3 |
increases expression |
ISO |
Zearalenone results in increased expression of ERICH3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 2:246,275,438...246,377,673
Ensembl chr 2:243,615,872...243,715,317
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G |
Erp27 |
endoplasmic reticulum protein 27 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ERP27 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660
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G |
Esco1 |
establishment of sister chromatid cohesion N-acetyltransferase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of ESCO1 mRNA |
CTD |
PMID:32119988 |
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NCBI chr18:1,630,560...1,686,803
Ensembl chr18:1,631,954...1,686,942
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G |
Espn |
espin |
increases expression |
ISO |
Zearalenone results in increased expression of ESPN mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases activity affects binding affects expression decreases expression affects response to substance |
ISO EXP |
[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein; Fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein]; Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone binds to and results in decreased activity of ESR1 protein; Zearalenone binds to and results in increased activity of ESR1 protein; Zearalenone promotes the reaction [ESR1 protein alternative form binds to ESR1 protein alternative form]; Zearalenone promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [NCOA2 protein binds to ESR1 protein] Zearalenone results in increased activity of ESR1 protein Zearalenone affects the expression of ESR1 mRNA; Zearalenone affects the expression of ESR1 protein Zearalenone analog binds to ESR1 protein; Zearalenone binds to ESR1 protein Zearalenone metabolite results in increased activity of ESR1 protein; Zearalenone results in increased activity of ESR1 protein Zearalenone results in decreased expression of ESR1 mRNA; Zearalenone results in decreased expression of ESR1 protein ESR1 protein affects the susceptibility to Zearalenone |
CTD |
PMID:9751507 PMID:11162928 PMID:11331656 PMID:11750080 PMID:12598185 PMID:12650720 PMID:15084758 PMID:15169976 PMID:19233257 PMID:19913605 PMID:20209442 PMID:22494775 PMID:22521637 PMID:25455890 PMID:27862621 PMID:28396216 PMID:28807876 PMID:28965971 PMID:29627501 PMID:30270565 PMID:31419471 PMID:33049310 PMID:33419253 More...
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NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects binding decreases expression increases expression |
ISO EXP |
Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone binds to and results in decreased activity of ESR2 protein; Zearalenone binds to and results in increased activity of ESR2 protein; Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein] Zearalenone binds to ESR2 protein Zearalenone analog binds to ESR2 protein; Zearalenone binds to ESR2 protein Zearalenone results in decreased expression of ESR2 mRNA [bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA; [Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]; [Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA Zearalenone results in increased expression of ESR2 mRNA Dextran Sulfate promotes the reaction [Zearalenone results in increased expression of ESR2 mRNA] |
CTD |
PMID:9751507 PMID:15084758 PMID:15169976 PMID:19913605 PMID:27338438 PMID:28807876 PMID:30270565 PMID:33049310 More...
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NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919
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G |
Etfb |
electron transfer flavoprotein subunit beta |
increases expression |
ISO |
Zearalenone results in increased expression of ETFB protein |
CTD |
PMID:25058043 |
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NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:93,851,858...93,866,068
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G |
Etfdh |
electron transfer flavoprotein dehydrogenase |
increases expression |
ISO |
Zearalenone results in increased expression of ETFDH protein |
CTD |
PMID:25058043 |
|
NCBI chr 2:167,038,707...167,060,758
Ensembl chr 2:164,729,749...164,762,745
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G |
Etnk2 |
ethanolamine kinase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of ETNK2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037
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G |
Fabp1 |
fatty acid binding protein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of FABP1 mRNA |
CTD |
PMID:32119988 |
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NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
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G |
Fam107a |
family with sequence similarity 107, member A |
decreases expression |
ISO |
Zearalenone results in decreased expression of FAM107A mRNA |
CTD |
PMID:19371625 |
|
NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
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G |
Fas |
Fas cell surface death receptor |
increases expression |
EXP |
Zearalenone results in increased expression of FAS mRNA; Zearalenone results in increased expression of FAS protein |
CTD |
PMID:30600648 |
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NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
increases expression |
EXP |
Zearalenone results in increased expression of FASLG mRNA; Zearalenone results in increased expression of FASLG protein |
CTD |
PMID:30600648 |
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NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
multiple interactions increases expression |
ISO |
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of FASN mRNA] |
CTD |
PMID:38159578 |
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NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
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G |
Fdx1 |
ferredoxin 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FDX1 mRNA; Zearalenone results in decreased expression of FDX1 protein |
CTD |
PMID:29758222 |
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NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:52,268,536...52,287,414
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G |
Figla |
folliculogenesis specific bHLH transcription factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of FIGLA mRNA |
CTD |
PMID:28089945 |
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NCBI chr 4:119,989,983...119,994,217
Ensembl chr 4:118,432,765...118,436,690
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G |
Filip1l |
filamin A interacting protein 1-like |
decreases expression |
ISO |
Zearalenone results in decreased expression of FILIP1L mRNA |
CTD |
PMID:36828454 |
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NCBI chr11:56,403,467...56,646,422
Ensembl chr11:42,940,467...43,177,415
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G |
Fkbp4 |
FKBP prolyl isomerase 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FKBP4 protein |
CTD |
PMID:25058043 |
|
NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:161,703,379...161,711,833
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FKBP5 mRNA |
CTD |
PMID:24412631 |
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NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674
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G |
Fn3krp |
fructosamine-3-kinase-related protein |
decreases expression |
ISO |
Zearalenone results in decreased expression of FN3KRP protein |
CTD |
PMID:36252740 |
|
NCBI chr10:107,186,695...107,195,419
Ensembl chr10:106,688,439...106,697,134
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G |
Fndc5 |
fibronectin type III domain containing 5 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FNDC5 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:141,481,590...141,490,731
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G |
Folr1 |
folate receptor alpha |
decreases expression |
ISO |
Zearalenone results in decreased expression of FOLR1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:156,219,460...156,230,667
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Zearalenone results in increased expression of FOS protein |
CTD |
PMID:27473017 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxd1 |
forkhead box D1 |
increases expression |
ISO |
Zearalenone results in increased expression of FOXD1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 2:31,436,802...31,439,222
Ensembl chr 2:29,702,558...29,704,978
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G |
Foxj1 |
forkhead box J1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FOXJ1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:102,065,163...102,069,945
Ensembl chr10:101,566,304...101,570,237
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G |
Foxo1 |
forkhead box O1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FOXO1 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxo3 |
forkhead box O3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of FOXO3 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561
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G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression multiple interactions |
EXP |
Zearalenone results in decreased expression of FSHB protein Gallic Acid inhibits the reaction [Zearalenone results in decreased expression of FSHB protein] |
CTD |
PMID:32858132 PMID:34723416 |
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NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
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G |
Fshr |
follicle stimulating hormone receptor |
decreases expression |
EXP |
Zearalenone results in decreased expression of FSHR mRNA; Zearalenone results in decreased expression of FSHR protein |
CTD |
PMID:29669061 |
|
NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785
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G |
G0s2 |
G0/G1switch 2 |
increases expression |
ISO |
Zearalenone results in increased expression of G0S2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
decreases activity multiple interactions |
EXP |
Zearalenone results in decreased activity of G6PD protein Gallic Acid inhibits the reaction [Zearalenone results in decreased activity of G6PD protein] |
CTD |
PMID:34723416 |
|
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
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|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Zearalenone results in increased expression of GADD45A mRNA |
CTD |
PMID:27862621 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
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|
G |
Galnt4 |
polypeptide N-acetylgalactosaminyltransferase 4 |
increases expression |
ISO |
Zearalenone results in increased expression of GALNT4 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 7:35,811,904...35,814,445
|
|
G |
Galr2 |
galanin receptor 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GALR2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:102,012,086...102,016,057
Ensembl chr10:101,514,471...101,517,176
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G |
Gap43 |
growth associated protein 43 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GAP43 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr11:71,882,131...71,975,799
Ensembl chr11:58,376,371...58,470,045
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|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
decreases expression |
ISO |
Zearalenone results in decreased expression of GAPDH protein |
CTD |
PMID:36252740 |
|
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235
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G |
Gars1 |
glycyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GARS1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:84,171,596...84,212,609
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G |
Gdf10 |
growth differentiation factor 10 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GDF10 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,237,261...9,249,343
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|
G |
Gdnf |
glial cell derived neurotrophic factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of GDNF protein |
CTD |
PMID:31419471 |
|
NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209
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G |
Gdpd5 |
glycerophosphodiester phosphodiesterase domain containing 5 |
increases expression |
ISO |
Zearalenone results in increased expression of GDPD5 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
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G |
Gfra2 |
GDNF family receptor alpha 2 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GFRA2 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr15:52,351,499...52,443,369
Ensembl chr15:45,941,828...46,033,714
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G |
Gins3 |
GINS complex subunit 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GINS3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
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|
G |
Gja1 |
gap junction protein, alpha 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GJA1 protein |
CTD |
PMID:27473017 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582
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|
G |
Gjb1 |
gap junction protein, beta 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GJB1 protein |
CTD |
PMID:27473017 |
|
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:66,501,820...66,509,925
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|
G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
EXP |
Zearalenone results in increased expression of GJB2 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177
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|
G |
Glg1 |
golgi glycoprotein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of GLG1 protein |
CTD |
PMID:36252740 |
|
NCBI chr19:56,034,248...56,133,538
Ensembl chr19:39,124,641...39,224,178
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|
G |
Glrx2 |
glutaredoxin 2 |
increases expression |
ISO |
Zearalenone results in increased expression of GLRX2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
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|
G |
Gnrh1 |
gonadotropin releasing hormone 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GNRH1 mRNA |
CTD |
PMID:29627501 |
|
NCBI chr15:46,147,878...46,152,086
Ensembl chr15:41,972,905...41,973,581 Ensembl chr15:41,972,905...41,973,581
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|
G |
Gnrhr |
gonadotropin releasing hormone receptor |
decreases expression |
EXP |
Zearalenone results in decreased expression of GNRHR protein |
CTD |
PMID:29627501 |
|
NCBI chr14:22,211,666...22,229,654
Ensembl chr14:21,856,871...21,874,861
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|
G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of GOT2 protein |
CTD |
PMID:25058043 |
|
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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|
G |
Gper1 |
G protein-coupled estrogen receptor 1 |
affects binding decreases expression |
ISO |
Zearalenone binds to GPER1 protein Zearalenone results in decreased expression of GPER1 mRNA |
CTD |
PMID:17088055 PMID:28965971 |
|
NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
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|
G |
Gpr142 |
G protein-coupled receptor 142 |
increases expression |
ISO |
Zearalenone results in increased expression of GPR142 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:99,840,069...99,843,410
Ensembl chr10:99,840,069...99,843,410
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|
G |
Gpt |
glutamic--pyruvic transaminase |
decreases expression multiple interactions increases activity increases expression |
ISO |
Zearalenone results in decreased expression of GPT protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased activity of GPT protein]]; corynoline inhibits the reaction [Zearalenone results in increased activity of GPT protein]; crocin inhibits the reaction [Zearalenone results in increased expression of GPT protein]; Plant Extracts inhibits the reaction [Zearalenone results in increased expression of GPT protein]; Zearalenone inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein] |
CTD |
PMID:17385802 PMID:25058043 PMID:25445755 PMID:26231423 PMID:36161741 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
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|
G |
Gpx1 |
glutathione peroxidase 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of GPX1 mRNA; Zearalenone results in decreased expression of GPX1 protein |
CTD |
PMID:32858132 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Grb7 |
growth factor receptor bound protein 7 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GRB7 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,444,004...83,453,052
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|
G |
Greb1 |
growth regulating estrogen receptor binding 1 |
increases expression |
ISO |
Zearalenone results in increased expression of GREB1 mRNA |
CTD |
PMID:19371625 PMID:22494775 PMID:28807876 PMID:33419253 PMID:36828454 |
|
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
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|
G |
Gsdmd |
gasdermin D |
decreases expression |
ISO |
Zearalenone results in decreased expression of GSDMD mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:107,542,083...107,547,055
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|
G |
Gspt1 |
G1 to S phase transition 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GSPT1 protein |
CTD |
PMID:36252740 |
|
NCBI chr10:4,867,687...4,904,186
Ensembl chr10:4,362,510...4,397,198
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|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity |
ISO |
lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] |
CTD |
PMID:25682699 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
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|
G |
Gstm2 |
glutathione S-transferase mu 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GSTM2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 2:198,312,179...198,316,962
Ensembl chr 2:195,544,426...195,628,961
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|
G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of GSTP1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
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|
G |
H19 |
H19 imprinted maternally expressed transcript |
decreases expression |
EXP |
Zearalenone results in decreased expression of H19 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr 1:207,160,175...207,162,851
Ensembl chr 1:197,730,698...197,733,134
|
|
G |
H2ax |
H2A.X variant histone |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of H2AX protein modified form Zearalenone results in decreased expression of H2AX protein |
CTD |
PMID:28089945 PMID:28552778 PMID:35504548 PMID:35650142 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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|
G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
decreases expression |
EXP |
Zearalenone results in decreased expression of HADHB mRNA; Zearalenone results in decreased expression of HADHB protein |
CTD |
PMID:32858132 |
|
NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869
|
|
G |
Hapln3 |
hyaluronan and proteoglycan link protein 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HAPLN3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177
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|
G |
Hat1 |
histone acetyltransferase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of HAT1 mRNA |
CTD |
PMID:32119988 |
|
NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
|
|
G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of HBA-A1 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,307,815...15,338,392
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|
G |
Hbb |
hemoglobin subunit beta |
decreases expression |
EXP |
Zearalenone results in decreased expression of HBB mRNA |
CTD |
PMID:17557909 |
|
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012
|
|
G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of HERPUD1 protein 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HERPUD1 protein]; HERPUD1 protein inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK1 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK3 protein]; HERPUD1 protein promotes the reaction [Zearalenone results in increased expression of CASP3 protein modified form] |
CTD |
PMID:30394307 |
|
NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424
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|
G |
Hes2 |
hes family bHLH transcription factor 2 |
increases expression |
ISO |
Zearalenone results in increased expression of HES2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:167,947,948...167,964,660
Ensembl chr 5:162,667,190...162,668,235
|
|
G |
Hist1h2bd |
histone cluster 1 H2B family member D |
decreases expression |
ISO |
Zearalenone results in decreased expression of H2BC5 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr17:47,488,627...47,489,008
|
|
G |
Hivep1 |
HIVEP zinc finger 1 |
increases expression |
ISO |
Zearalenone results in increased expression of HIVEP1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr17:22,790,855...22,920,359
Ensembl chr17:22,585,016...22,711,956
|
|
G |
Hk2 |
hexokinase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of HK2 mRNA |
CTD |
PMID:32119988 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530
|
|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HMGCS1 mRNA |
CTD |
PMID:25424538 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100
|
|
G |
Hmgn2 |
high mobility group nucleosomal binding domain 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HMGN2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:151,475,907...151,479,361
Ensembl chr 5:146,192,126...146,195,521 Ensembl chr16:146,192,126...146,195,521
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|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of HMOX1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline promotes the reaction [Zearalenone results in increased expression of HMOX1 protein]]; corynoline promotes the reaction [Zearalenone results in increased expression of HMOX1 protein] |
CTD |
PMID:36161741 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
multiple interactions |
ISO |
[deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA |
CTD |
PMID:28865950 |
|
NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320
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|
G |
Hoxa10 |
homeobox A10 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HOXA10 mRNA |
CTD |
PMID:27862621 |
|
NCBI chr 4:82,662,204...82,671,490
Ensembl chr 4:81,331,591...81,340,919
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|
G |
Hpdl |
4-hydroxyphenylpyruvate dioxygenase-like |
increases expression |
ISO |
Zearalenone results in increased expression of HPDL mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 5:135,523,258...135,524,864
Ensembl chr 5:130,286,631...130,288,233
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|
G |
Hras |
HRas proto-oncogene, GTPase |
decreases expression |
ISO |
Zearalenone results in decreased expression of HRAS mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615
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|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of HSD11B1 mRNA; Zearalenone results in decreased expression of HSD11B1 protein |
CTD |
PMID:29669061 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687
|
|
G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSD17B1 protein |
CTD |
PMID:31419471 |
|
NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,009,728...86,011,927
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|
G |
Hsd17b11 |
hydroxysteroid (17-beta) dehydrogenase 11 |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of HSD17B11 protein |
CTD |
PMID:25058043 |
|
NCBI chr14:5,997,893...6,047,816
Ensembl chr14:5,711,964...5,743,161
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|
G |
Hsd17b14 |
hydroxysteroid (17-beta) dehydrogenase 14 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSD17B14 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:105,165,695...105,176,045
Ensembl chr 1:96,029,284...96,039,883
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|
G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
increases expression |
EXP |
Zearalenone results in increased expression of HSD17B2 mRNA |
CTD |
PMID:20607812 |
|
NCBI chr19:62,662,320...62,733,944
Ensembl chr19:45,753,574...45,825,202
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|
G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
decreases expression decreases activity |
ISO EXP |
Zearalenone results in decreased expression of HSD17B3 mRNA Zearalenone results in decreased activity of HSD17B3 protein Zearalenone results in decreased expression of HSD17B3 mRNA; Zearalenone results in decreased expression of HSD17B3 protein |
CTD |
PMID:24512812 PMID:29669061 |
|
NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,027,229...1,058,554
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|
G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSD17B4 protein |
CTD |
PMID:31419471 |
|
NCBI chr18:45,515,427...45,604,467
Ensembl chr18:43,328,824...43,417,952
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|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases expression decreases activity |
ISO EXP |
Zearalenone results in decreased expression of HSD3B1 mRNA Zearalenone results in decreased activity of HSD3B1 protein |
CTD |
PMID:24512812 PMID:29669061 |
|
NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999
|
|
G |
Hsd3b2 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
affects expression |
EXP |
Zearalenone affects the expression of HSD3B2 mRNA |
CTD |
PMID:29627501 |
|
NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:186,095,897...186,101,852
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|
G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSP90AB1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488
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|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of HSPA1A mRNA; Zearalenone results in increased expression of HSPA1A protein Zearalenone results in decreased expression of HSPA1A protein |
CTD |
PMID:19051279 PMID:36252740 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227
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|
G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression |
ISO |
Zearalenone results in increased expression of HSPA1B mRNA |
CTD |
PMID:25424538 PMID:27862621 |
|
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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|
G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSPA4 protein |
CTD |
PMID:25058043 |
|
NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in increased expression of HSPA5 protein]; 4-phenylbutylamine promotes the reaction [Zearalenone results in increased expression of HSPA5 protein] |
CTD |
PMID:30394307 PMID:31982503 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Hspb1 |
heat shock protein family B (small) member 1 |
increases expression |
ISO |
Zearalenone results in increased expression of HSPB1 protein |
CTD |
PMID:19051279 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743
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|
G |
Hspb8 |
heat shock protein family B (small) member 8 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSPB8 protein |
CTD |
PMID:36252740 |
|
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
|
|
G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of HSPH1 protein |
CTD |
PMID:36252740 |
|
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:5,390,922...5,410,224
|
|
G |
Id1 |
inhibitor of DNA binding 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ID1 mRNA |
CTD |
PMID:25424538 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419
|
|
G |
Id2 |
inhibitor of DNA binding 2 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of ID2 mRNA [Tamoxifen co-treated with Zearalenone] results in increased expression of ID2 mRNA |
CTD |
PMID:30138655 |
|
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400
|
|
G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
increases expression |
ISO |
Zearalenone results in increased expression of IDH3A protein |
CTD |
PMID:25058043 |
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NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:54,971,740...54,991,084
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G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of IDO1 mRNA |
CTD |
PMID:36828454 |
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NCBI chr16:74,133,259...74,145,328
Ensembl chr16:67,430,578...67,442,730
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G |
Ifitm3 |
interferon induced transmembrane protein 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of IFITM3 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:196,111,043...196,112,203
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G |
Igf1 |
insulin-like growth factor 1 |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of IGF1 mRNA Zearalenone results in decreased expression of IGF1 mRNA |
CTD |
PMID:27757495 PMID:28965971 |
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NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of IGFBP3 mRNA |
CTD |
PMID:28965971 PMID:36828454 |
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NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
decreases expression |
ISO |
Zearalenone results in decreased expression of IGFBP6 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
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G |
Igsf9 |
immunoglobulin superfamily, member 9 |
decreases expression |
ISO |
Zearalenone results in decreased expression of IGSF9 mRNA |
CTD |
PMID:36828454 |
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NCBI chr13:87,480,979...87,497,974
Ensembl chr13:84,948,619...84,965,607
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G |
Ikzf2 |
IKAROS family zinc finger 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of IKZF2 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 9:78,495,670...78,640,896
Ensembl chr 9:71,042,440...71,190,867
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G |
Il10 |
interleukin 10 |
multiple interactions increases expression |
ISO |
lycopene inhibits the reaction [Zearalenone results in increased expression of IL10] |
CTD |
PMID:25682699 |
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NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
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G |
Il12a |
interleukin 12A |
increases expression |
ISO |
Zearalenone results in increased expression of IL12A mRNA |
CTD |
PMID:36828454 |
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NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734
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G |
Il13 |
interleukin 13 |
increases expression |
ISO |
Zearalenone results in increased expression of IL13 mRNA |
CTD |
PMID:27757495 |
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NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737
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G |
Il18 |
interleukin 18 |
increases secretion multiple interactions increases expression |
ISO |
Zearalenone results in increased secretion of IL18 protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL18 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased secretion of IL18 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein] |
CTD |
PMID:30270565 PMID:38159578 |
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NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion |
ISO EXP |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased expression of IL1B protein]]; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL1B protein; corynoline inhibits the reaction [Zearalenone results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein] Zearalenone results in increased expression of IL1B; Zearalenone results in increased expression of IL1B mRNA; Zearalenone results in increased expression of IL1B protein Zearalenone results in increased secretion of IL1B protein Zearalenone results in increased expression of IL1B protein modified form 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form] [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL1B mRNA |
CTD |
PMID:16687389 PMID:25682699 PMID:30270565 PMID:31586597 PMID:35090964 PMID:36161741 PMID:38159578 More...
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
decreases expression |
ISO |
Zearalenone results in decreased expression of IL1RN mRNA |
CTD |
PMID:36828454 |
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NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
multiple interactions increases expression |
ISO |
lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] |
CTD |
PMID:25682699 |
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NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
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G |
Il4 |
interleukin 4 |
increases expression |
ISO |
Zearalenone results in increased expression of IL4 mRNA |
CTD |
PMID:27757495 |
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NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
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G |
Il4r |
interleukin 4 receptor |
increases expression |
ISO |
Zearalenone results in increased expression of IL4R mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
ISO |
Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of IL6 mRNA]; lycopene inhibits the reaction [Zearalenone results in increased expression of IL6] [Lipopolysaccharides co-treated with Zearalenone] results in increased secretion of IL6 protein; [Zearalenone co-treated with Aflatoxin B1] results in decreased expression of IL6 mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL6 mRNA |
CTD |
PMID:16687389 PMID:25682699 PMID:28965971 PMID:32328699 PMID:35090964 |
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
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G |
Immt |
inner membrane mitochondrial protein |
increases expression |
ISO |
Zearalenone results in increased expression of IMMT protein |
CTD |
PMID:25058043 |
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NCBI chr 4:105,438,657...105,477,370
Ensembl chr 4:103,880,459...103,919,109
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G |
Impdh2 |
inosine monophosphate dehydrogenase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of IMPDH2 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:109,256,728...109,261,359
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G |
Inhba |
inhibin subunit beta A |
decreases expression |
ISO |
Zearalenone results in decreased expression of INHBA mRNA |
CTD |
PMID:30138655 |
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NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982
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G |
Ipo13 |
importin 13 |
increases expression |
ISO |
Zearalenone results in increased expression of IPO13 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 5:131,433,770...131,454,044
Ensembl chr 5:131,433,776...131,454,043
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G |
Ism1 |
isthmin 1 |
increases expression |
ISO |
Zearalenone results in increased expression of ISM1 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 3:147,476,983...147,555,900
Ensembl chr 3:127,021,865...127,101,894
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G |
Isyna1 |
inositol-3-phosphate synthase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ISYNA1 protein |
CTD |
PMID:36252740 |
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NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,839,145...18,841,979
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G |
Itpk1 |
inositol-tetrakisphosphate 1-kinase |
increases expression |
ISO |
Zearalenone results in increased expression of ITPK1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 6:127,475,589...127,609,320
Ensembl chr 6:121,710,755...121,844,107
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G |
Jag1 |
jagged canonical Notch ligand 1 |
increases expression |
ISO EXP |
Zearalenone results in increased expression of JAG1 mRNA |
CTD |
PMID:30138655 PMID:32858132 |
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NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
scutellarin inhibits the reaction [Zearalenone results in increased expression of JUN protein] |
CTD |
PMID:27473017 PMID:36252740 |
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NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
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G |
Kat2b |
lysine acetyltransferase 2B |
increases expression |
ISO |
Zearalenone results in increased expression of KAT2B mRNA |
CTD |
PMID:32119988 |
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NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
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G |
Kazn |
kazrin, periplakin interacting protein |
increases expression |
ISO |
Zearalenone results in increased expression of KAZN mRNA |
CTD |
PMID:36828454 |
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NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
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G |
Kbtbd8 |
kelch repeat and BTB domain containing 8 |
increases expression |
ISO |
Zearalenone results in increased expression of KBTBD8 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 4:129,232,781...129,245,608
Ensembl chr 4:127,676,141...127,687,697
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G |
Kcnf1 |
potassium voltage-gated channel modifier subfamily F member 1 |
increases expression |
ISO |
Zearalenone results in increased expression of KCNF1 mRNA |
CTD |
PMID:19371625 PMID:36828454 |
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NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979
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G |
Kcnj2 |
potassium inwardly-rectifying channel, subfamily J, member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of KCNJ2 mRNA |
CTD |
PMID:36828454 |
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NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,060,821...96,071,445
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G |
Kcnj5 |
potassium inwardly-rectifying channel, subfamily J, member 5 |
increases expression |
ISO |
Zearalenone results in increased expression of KCNJ5 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 8:38,981,598...39,011,197
Ensembl chr 8:30,724,925...30,753,518
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G |
Kcnk15 |
potassium two pore domain channel subfamily K member 15 |
increases expression |
ISO |
Zearalenone results in increased expression of KCNK15 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 3:172,934,659...172,940,877
Ensembl chr 3:152,515,237...152,521,455
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G |
Kctd20 |
potassium channel tetramerization domain containing 20 |
increases expression |
ISO |
Zearalenone results in increased expression of KCTD20 mRNA |
CTD |
PMID:19371625 |
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NCBI chr20:7,015,828...7,032,766
Ensembl chr20:7,015,833...7,032,761
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G |
Kdm4a |
lysine demethylase 4A |
decreases expression |
ISO |
Zearalenone results in decreased expression of KDM4A mRNA |
CTD |
PMID:24412631 |
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NCBI chr 5:136,958,178...137,004,942
Ensembl chr 5:131,672,754...131,719,501
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G |
Kitlg |
KIT ligand |
decreases expression |
ISO |
Zearalenone results in decreased expression of KITLG mRNA |
CTD |
PMID:27757495 |
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NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214
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G |
Kmt5a |
lysine methyltransferase 5A |
increases expression |
ISO |
Zearalenone results in increased expression of KMT5A mRNA |
CTD |
PMID:32119988 |
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NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711
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G |
Kras |
KRAS proto-oncogene, GTPase |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of KRAS mRNA Zearalenone results in decreased expression of KRAS mRNA |
CTD |
PMID:29758222 PMID:30717214 |
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NCBI chr 4:179,916,255...179,949,613
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G |
Krt10 |
keratin 10 |
decreases expression |
ISO |
Zearalenone results in decreased expression of KRT10 protein |
CTD |
PMID:25058043 |
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NCBI chr10:84,834,865...84,839,160
Ensembl chr10:84,338,706...84,343,701
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G |
Krt17 |
keratin 17 |
decreases expression |
ISO |
Zearalenone results in decreased expression of KRT17 mRNA |
CTD |
PMID:19371625 |
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NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,178,675...85,183,392
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G |
Krt4 |
keratin 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of KRT4 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
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G |
Krt5 |
keratin 5 |
increases expression |
ISO |
Zearalenone results in increased expression of KRT5 mRNA |
CTD |
PMID:28965971 |
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NCBI chr 7:134,724,840...134,730,569
Ensembl chr 7:132,846,136...132,851,850
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G |
Krt7 |
keratin 7 |
increases expression |
EXP |
Zearalenone results in increased expression of KRT7 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:132,528,895...132,545,052
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G |
Ldlr |
low density lipoprotein receptor |
increases expression decreases expression |
ISO EXP |
Zearalenone results in increased expression of LDLR mRNA Zearalenone results in decreased expression of LDLR mRNA; Zearalenone results in decreased expression of LDLR protein |
CTD |
PMID:32119988 PMID:32858132 |
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NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580
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G |
Lgals1 |
galectin 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of LGALS1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:110,481,392...110,488,345
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G |
Lhb |
luteinizing hormone subunit beta |
decreases expression multiple interactions |
EXP |
Zearalenone results in decreased expression of LHB protein Gallic Acid inhibits the reaction [Zearalenone results in decreased expression of LHB protein] |
CTD |
PMID:29627501 PMID:32858132 PMID:34723416 |
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NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions |
ISO |
[Colforsin co-treated with Zearalenone] results in increased expression of LHCGR mRNA |
CTD |
PMID:26783879 |
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NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521
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G |
Lhx8 |
LIM homeobox 8 |
decreases expression |
ISO |
Zearalenone results in decreased expression of LHX8 mRNA; Zearalenone results in decreased expression of LHX8 protein |
CTD |
PMID:28089945 |
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NCBI chr 2:245,904,712...245,929,376
Ensembl chr 2:243,244,961...243,269,416
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G |
Lmna |
lamin A/C |
increases expression |
ISO |
Zearalenone results in increased expression of LMNA protein |
CTD |
PMID:36252740 |
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NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:173,939,751...173,960,423
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G |
Lmnb1 |
lamin B1 |
increases expression |
ISO |
Zearalenone results in increased expression of LMNB1 protein |
CTD |
PMID:36252740 |
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NCBI chr18:52,373,939...52,413,284
Ensembl chr18:50,175,874...50,214,502
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G |
Lonrf2 |
LON peptidase N-terminal domain and ring finger 2 |
increases expression |
ISO |
Zearalenone results in increased expression of LONRF2 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 9:48,524,962...48,566,353
Ensembl chr 9:41,034,628...41,070,649
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G |
Lpal2 |
lipoprotein(a) like 2 |
increases expression |
ISO |
Zearalenone results in increased expression of LPAL2 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 4:165,207,378...165,264,321
Ensembl chr 4:165,207,328...165,264,340
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G |
Lpin1 |
lipin 1 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of LPIN1 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of LPIN1 protein] |
CTD |
PMID:38159578 |
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NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:39,312,748...39,417,097
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G |
Lrrc4 |
leucine rich repeat containing 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of LRRC4 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 4:57,433,518...57,437,114
Ensembl chr 4:57,433,428...57,437,911
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G |
Lsp1 |
lymphocyte-specific protein 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of LSP1 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:197,614,687...197,648,416
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G |
Lyar |
Ly1 antibody reactive |
increases expression |
ISO |
Zearalenone results in increased expression of LYAR mRNA |
CTD |
PMID:36828454 |
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NCBI chr14:76,789,193...76,802,973
Ensembl chr14:72,576,879...72,590,612
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G |
Mak16 |
MAK16 homolog |
increases expression |
ISO |
Zearalenone results in increased expression of RBM13 mRNA |
CTD |
PMID:19371625 |
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NCBI chr16:67,675,757...67,684,188
Ensembl chr16:60,972,697...60,983,243
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
increases expression |
ISO |
Zearalenone results in increased expression of MAP1LC3A mRNA |
CTD |
PMID:34537261 |
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NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:143,783,024...143,784,670
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression |
EXP ISO |
Zearalenone results in increased expression of MAP1LC3B protein |
CTD |
PMID:31586597 PMID:32858132 PMID:34537261 |
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NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MAP2K1 protein |
CTD |
PMID:36252740 |
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NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
decreases expression multiple interactions increases expression |
ISO |
Zearalenone results in decreased expression of MAP2K4 protein scutellarin inhibits the reaction [Zearalenone results in increased expression of MAP2K4 protein] |
CTD |
PMID:36252740 |
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NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993
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G |
Mapk1 |
mitogen activated protein kinase 1 |
decreases phosphorylation multiple interactions increases phosphorylation |
ISO EXP |
Zearalenone results in decreased phosphorylation of MAPK1 protein HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK1 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased phosphorylation of MAPK1 protein]; Zearalenone results in decreased expression of and results in decreased phosphorylation of MAPK1 protein |
CTD |
PMID:30394307 PMID:32858132 PMID:34716709 PMID:38159578 |
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NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk13 |
mitogen activated protein kinase 13 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MAPK13 mRNA |
CTD |
PMID:19371625 |
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NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
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G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases phosphorylation multiple interactions increases phosphorylation |
ISO EXP |
Zearalenone results in decreased phosphorylation of MAPK3 protein HERPUD1 protein promotes the reaction [Zearalenone results in decreased phosphorylation of MAPK3 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:30394307 PMID:32858132 PMID:38159578 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation increases expression |
ISO |
Zearalenone results in increased phosphorylation of MAPK8 protein Zearalenone results in increased expression of MAPK8 mRNA |
CTD |
PMID:21767629 PMID:30717214 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
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G |
Mas1 |
MAS1 proto-oncogene, G protein-coupled receptor |
increases expression |
ISO |
Zearalenone results in increased expression of MAS1 mRNA |
CTD |
PMID:24412631 |
|
NCBI chr 1:50,428,064...50,459,537
Ensembl chr 1:47,880,309...47,911,709
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G |
Mat2b |
methionine adenosyltransferase 2 non-catalytic beta subunit |
decreases expression |
ISO |
Zearalenone results in decreased expression of MAT2B protein |
CTD |
PMID:36252740 |
|
NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
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G |
Mdh2 |
malate dehydrogenase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of MDH2 protein |
CTD |
PMID:25058043 |
|
NCBI chr12:26,530,886...26,543,841
Ensembl chr12:20,894,262...20,907,271
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G |
Mdk |
midkine |
decreases expression |
ISO |
Zearalenone results in decreased expression of MDK mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:77,901,158...77,903,130
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G |
Meox1 |
mesenchyme homeobox 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MEOX1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:87,318,668...87,338,169
Ensembl chr10:86,818,478...86,837,660
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|
G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
increases expression |
ISO |
Zearalenone results in increased expression of MET mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876
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|
G |
Mfap2 |
microfibril associated protein 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MFAP2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 5:158,595,121...158,603,283
Ensembl chr 5:153,314,711...153,320,259
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|
G |
Mfge8 |
milk fat globule EGF and factor V/VIII domain containing |
decreases expression |
ISO |
Zearalenone results in decreased expression of MFGE8 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:133,064,665...133,080,073
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|
G |
Mfn2 |
mitofusin 2 |
increases expression |
ISO |
Zearalenone results in increased expression of MFN2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342
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|
G |
Mgat3 |
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
increases expression |
ISO |
Zearalenone results in increased expression of MGAT3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 7:111,708,353...111,761,825
Ensembl chr 7:111,675,730...111,762,026
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|
G |
Mgll |
monoglyceride lipase |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of MGLL protein |
CTD |
PMID:25058043 |
|
NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:121,192,195...121,294,179
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|
G |
Mill1 |
MHC I like leukocyte 1 |
increases expression |
ISO |
Zearalenone results in increased expression of MICA mRNA |
CTD |
PMID:27757495 |
|
NCBI chr 1:87,500,591...87,526,983
Ensembl chr 1:78,372,802...78,398,930
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|
G |
Mir146b |
microRNA 146b |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR146B mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:245,203,438...245,203,525
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|
G |
Mir185 |
microRNA 185 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR185 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
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|
G |
Mir19a |
microRNA 19a |
increases expression |
ISO |
Zearalenone results in increased expression of MIR19A mRNA |
CTD |
PMID:30717214 |
|
NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993
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|
G |
Mir200a |
microRNA 200a |
multiple interactions |
ISO |
Zearalenone results in decreased expression of and affects the secretion of MIR200A mRNA |
CTD |
PMID:33419253 |
|
NCBI chr 5:171,930,717...171,930,805
|
|
G |
Mir200b |
microRNA 200b |
multiple interactions |
ISO |
Zearalenone results in decreased expression of and affects the secretion of MIR200B mRNA |
CTD |
PMID:33419253 |
|
NCBI chr 5:171,931,495...171,931,589
Ensembl chr 5:166,649,272...166,649,366
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|
G |
Mir200c |
microRNA 200c |
multiple interactions |
ISO |
Zearalenone results in increased expression of and results in decreased secretion of MIR200C mRNA |
CTD |
PMID:33419253 |
|
NCBI chr 4:159,209,965...159,210,033
|
|
G |
Mir210 |
microRNA 210 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR210 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454
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|
G |
Mir221 |
microRNA 221 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of MIR221 mRNA [Zearalenone co-treated with deoxynivalenol] results in decreased expression of MIR221 mRNA |
CTD |
PMID:30717214 PMID:35090964 |
|
NCBI chr X:6,023,182...6,023,290
Ensembl chr X:3,429,465...3,429,573
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|
G |
Mir301a |
microRNA 301a |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR301 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr10:72,422,599...72,422,698
Ensembl chr10:71,925,336...71,925,435
|
|
G |
Mir326 |
microRNA 326 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR326 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
|
|
G |
Mir410 |
microRNA 410 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR410 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434
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|
G |
Mir411 |
microRNA 411 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR411 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:128,723,184...128,723,279
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|
G |
Mir429 |
microRNA 429 |
decreases secretion |
ISO |
Zearalenone results in decreased secretion of MIR429 mRNA |
CTD |
PMID:33419253 |
|
NCBI chr 5:171,929,682...171,929,766
Ensembl chr 5:166,647,459...166,647,543
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|
G |
Mir451a |
microRNA 451a |
increases expression |
ISO |
Zearalenone results in increased expression of MIR451A mRNA |
CTD |
PMID:36828454 |
|
NCBI chr10:63,459,569...63,459,640
Ensembl chr10:62,961,520...62,961,591
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G |
Mir615 |
microRNA 615 |
decreases expression |
ISO |
Zearalenone results in decreased expression of MIR615 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 7:134,151,887...134,151,978
Ensembl chr 7:134,151,887...134,151,978
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|
G |
Mir96 |
microRNA 96 |
affects expression |
ISO |
Zearalenone affects the expression of MIR96 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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|
G |
Mki67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
Zearalenone results in increased expression of MKI67 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762
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|
G |
Mlh1 |
mutL homolog 1 |
increases expression |
ISO |
Zearalenone results in increased expression of MLH1 mRNA; Zearalenone results in increased expression of MLH1 protein |
CTD |
PMID:28552778 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617
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|
G |
Mlph |
melanophilin |
increases expression |
ISO |
Zearalenone results in increased expression of MLPH mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 9:91,507,410...91,542,984
Ensembl chr 9:91,507,591...91,542,983
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|
G |
Mmp2 |
matrix metallopeptidase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of MMP2 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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|
G |
Mmp7 |
matrix metallopeptidase 7 |
increases expression |
EXP |
Zearalenone results in increased expression of MMP7 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902
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|
G |
Mpo |
myeloperoxidase |
multiple interactions increases secretion increases activity |
ISO EXP |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased activity of MPO protein]]; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of MPO protein; corynoline inhibits the reaction [Zearalenone results in increased activity of MPO protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein] Zearalenone results in increased secretion of MPO protein Gallic Acid inhibits the reaction [Zearalenone results in increased activity of MPO protein] |
CTD |
PMID:30270565 PMID:34723416 PMID:36161741 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819
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|
G |
Msmb |
microseminoprotein, beta |
increases expression |
ISO |
Zearalenone results in increased expression of MSMB mRNA |
CTD |
PMID:19371625 |
|
NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
|
|
G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of ATP6 mRNA [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP6 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:7,919...8,599
|
|
G |
Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
multiple interactions |
ISO |
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ATP8 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of ATP8 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of ATP8 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:7,758...7,961
|
|
G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of COX1 mRNA [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in decreased expression of COX1 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of COX1 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of COX1 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:5,323...6,867
|
|
G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
multiple interactions decreases expression |
ISO |
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in decreased expression of COX3 mRNA; [Plant Extracts co-treated with Zearalenone] results in decreased expression of COX3 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of COX3 mRNA Zearalenone results in decreased expression of COX3 mRNA |
CTD |
PMID:34015425 |
|
NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
|
|
G |
Mt-nd2 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 |
multiple interactions |
ISO |
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND2 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND2 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND2 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:3,904...4,942
|
|
G |
Mt-nd3 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 |
multiple interactions |
ISO |
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND3 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND3 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND3 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:9,451...9,798
|
|
G |
Mt-nd4 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of ND4 mRNA [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone co-treated with beauvericin] results in decreased expression of ND4 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND4 mRNA |
CTD |
PMID:34015425 |
|
NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537 NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537
|
|
G |
Mt-nd4l |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L |
multiple interactions |
ISO |
[Plant Extracts co-treated with Zearalenone] results in increased expression of ND4L mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND4L mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:9,870...10,166
|
|
G |
Mt-nd5 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 |
multiple interactions |
ISO |
[Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND5 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND5 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND5 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:11,736...13,565
|
|
G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of ND6 mRNA [Plant Extracts co-treated with ochratoxin A co-treated with Zearalenone] results in increased expression of ND6 mRNA; [Plant Extracts co-treated with Zearalenone] results in increased expression of ND6 mRNA; [Zearalenone co-treated with ochratoxin A] results in increased expression of ND6 mRNA |
CTD |
PMID:34015425 |
|
Ensembl chr MT:13,543...14,061
|
|
G |
Mtarc2 |
mitochondrial amidoxime reducing component 2 |
increases expression |
ISO |
Zearalenone results in increased expression of MTARC2 protein |
CTD |
PMID:25058043 |
|
NCBI chr13:98,894,347...98,928,754
|
|
G |
Mthfd1l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like |
increases expression |
ISO |
Zearalenone results in increased expression of MTHFD1L protein |
CTD |
PMID:25058043 |
|
NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:40,444,008...40,632,905
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|
G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation multiple interactions |
EXP ISO |
Zearalenone results in decreased phosphorylation of MTOR protein 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:31586597 PMID:31982503 PMID:32858132 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
|
|
G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
[Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC2 mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased secretion of MUC2 protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC2 mRNA; [Aflatoxin M1 co-treated with Zearalenone] results in decreased secretion of MUC2 protein |
CTD |
PMID:30904571 |
|
NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:196,799,517...196,831,756
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G |
Muc4 |
mucin 4, cell surface associated |
increases expression |
EXP |
Zearalenone results in increased expression of MUC4 mRNA |
CTD |
PMID:17557909 |
|
NCBI chr11:81,513,321...81,575,200
|
|
G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of MUC5AC mRNA [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC5AC mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in increased secretion of MUC5AC protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC5AC mRNA; Zearalenone results in increased expression of and results in increased secretion of MUC5AC protein |
CTD |
PMID:24496642 PMID:30904571 |
|
NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:196,864,336...196,896,475
|
|
G |
Muc5b |
mucin 5B, oligomeric mucus/gel-forming |
multiple interactions increases expression |
ISO |
[Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased expression of MUC5B mRNA; [Aflatoxin M1 co-treated with Zearalenone co-treated with ochratoxin A] results in decreased secretion of MUC5B protein; [Aflatoxin M1 co-treated with Zearalenone] results in decreased expression of MUC5B mRNA; [Aflatoxin M1 co-treated with Zearalenone] results in decreased secretion of MUC5B protein; Zearalenone results in increased expression of and results in increased secretion of MUC5B protein Zearalenone results in increased expression of MUC5B mRNA |
CTD |
PMID:24496642 PMID:30904571 |
|
NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:196,916,825...196,949,250
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
ISO |
Zearalenone results in increased expression of MYC mRNA Zearalenone results in increased expression of MYC protein |
CTD |
PMID:27473017 PMID:28965971 PMID:36828454 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
|
|
G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
increases expression |
ISO |
Zearalenone results in increased expression of MYD88 mRNA |
CTD |
PMID:27757495 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
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|
G |
N4bp3 |
Nedd4 binding protein 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of N4BP3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr10:36,400,053...36,407,609
Ensembl chr10:35,899,096...35,907,001
|
|
G |
Naa10 |
N(alpha)-acetyltransferase 10, NatA catalytic subunit |
decreases expression |
ISO |
Zearalenone results in decreased expression of NAA10 protein |
CTD |
PMID:36252740 |
|
NCBI chr X:156,807,378...156,812,632
Ensembl chr X:151,656,056...151,661,252
|
|
G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NARS1 protein |
CTD |
PMID:36252740 |
|
NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
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|
G |
Nasp |
nuclear autoantigenic sperm protein |
decreases expression |
EXP |
Zearalenone results in decreased expression of NASP mRNA |
CTD |
PMID:17557909 |
|
NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
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|
G |
Ncmap |
noncompact myelin associated protein |
increases expression |
ISO |
Zearalenone results in increased expression of NCMAP mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:152,893,173...152,921,175
Ensembl chr 5:147,610,677...147,618,775
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|
G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]; Zearalenone promotes the reaction [NCOA2 protein binds to ESR1 protein] |
CTD |
PMID:15084758 PMID:28807876 |
|
NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451
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G |
Ncr3lg1 |
natural killer cell cytotoxicity receptor 3 ligand 1 |
increases expression |
ISO |
Zearalenone results in increased expression of NCR3LG1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 1:105,701,953...105,718,251
Ensembl chr 1:96,574,455...96,580,466
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G |
Ndrg1 |
N-myc downstream regulated 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NDRG1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880
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G |
Nectin4 |
nectin cell adhesion molecule 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NECTIN4 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr13:86,335,027...86,354,152
Ensembl chr13:83,803,184...83,821,709
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G |
Neil2 |
nei-like DNA glycosylase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of NEIL2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr15:41,620,650...41,631,551
Ensembl chr15:37,445,381...37,454,863
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of NFE2L2 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline promotes the reaction [Zearalenone results in increased expression of NFE2L2 protein]]; corynoline promotes the reaction [Zearalenone results in increased expression of NFE2L2 protein] |
CTD |
PMID:36161741 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
increases phosphorylation multiple interactions |
EXP ISO |
Zearalenone results in increased phosphorylation of NFKBIA protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of NFKBIA protein]]; corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:31586597 PMID:36161741 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
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G |
Ngef |
neuronal guanine nucleotide exchange factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of NGEF mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:88,146,956...88,244,914
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G |
Niban2 |
niban apoptosis regulator 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NIBAN2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 3:36,572,356...36,621,968
Ensembl chr 3:16,174,659...16,224,293
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression multiple interactions |
ISO EXP |
Zearalenone results in increased expression of NLRP3 mRNA; Zearalenone results in increased expression of NLRP3 protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 protein; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein] NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein] |
CTD |
PMID:30270565 PMID:31586597 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
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G |
Nme1 |
NME/NM23 nucleoside diphosphate kinase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of NME1 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr10:79,403,939...79,426,620
Ensembl chr10:78,906,083...78,916,408
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G |
Nmnat1 |
nicotinamide nucleotide adenylyltransferase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NMNAT1 mRNA |
CTD |
PMID:38159578 |
|
NCBI chr 5:165,193,301...165,211,213
Ensembl chr 5:159,910,242...159,928,180
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G |
Nmnat2 |
nicotinamide nucleotide adenylyltransferase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NMNAT2 mRNA |
CTD |
PMID:38159578 |
|
NCBI chr13:67,655,794...67,831,609
Ensembl chr13:65,105,950...65,278,484
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G |
Nmral1 |
NmrA like redox sensor 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NMRAL1 protein |
CTD |
PMID:36252740 |
|
NCBI chr10:10,841,693...10,850,199
Ensembl chr10:10,841,799...10,850,192
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G |
Nobox |
NOBOX oogenesis homeobox |
decreases expression |
ISO |
Zearalenone results in decreased expression of NOBOX mRNA |
CTD |
PMID:28089945 |
|
NCBI chr 4:73,128,926...73,134,431
Ensembl chr 4:72,128,931...72,134,436
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G |
Notch1 |
notch receptor 1 |
multiple interactions |
ISO |
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of NOTCH1 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531
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G |
Npy1r |
neuropeptide Y receptor Y1 |
increases expression |
ISO |
Zearalenone results in increased expression of NPY1R mRNA |
CTD |
PMID:36828454 |
|
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
ISO |
Zearalenone results in increased expression of NR1H3 mRNA |
CTD |
PMID:32119988 PMID:38159578 |
|
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity decreases expression multiple interactions affects binding |
ISO EXP |
Zearalenone results in increased activity of NR1I2 protein Zearalenone results in decreased expression of NR1I2 mRNA Zearalenone binds to and results in increased activity of NR1I2 protein; Zearalenone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4] Zearalenone binds to NR1I2 protein |
CTD |
PMID:15569515 PMID:20607812 PMID:33049310 PMID:36893891 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
Zearalenone results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
|
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NR3C1 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
decreases expression multiple interactions increases expression |
ISO |
Zearalenone results in decreased expression of NR4A1 protein Colforsin promotes the reaction [Zearalenone results in increased expression of NR4A1 mRNA] |
CTD |
PMID:24512812 PMID:26783879 |
|
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of NR5A1 mRNA; Zearalenone results in decreased expression of NR5A1 protein |
CTD |
PMID:29669061 |
|
NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:22,465,502...22,486,328
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G |
Nrip1 |
nuclear receptor interacting protein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of NRIP1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr11:28,382,835...28,466,483
Ensembl chr11:14,895,553...14,981,761
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G |
Nrtn |
neurturin |
increases expression |
ISO |
Zearalenone results in increased expression of NRTN mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,581,975...1,583,102
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G |
Nt5c |
5', 3'-nucleotidase, cytosolic |
decreases expression |
ISO |
Zearalenone results in decreased expression of NT5C protein |
CTD |
PMID:36252740 |
|
NCBI chr10:101,238,552...101,240,666
Ensembl chr10:100,739,588...100,741,954
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G |
Nubp2 |
NUBP iron-sulfur cluster assembly factor 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NUBP2 protein |
CTD |
PMID:36252740 |
|
NCBI chr10:14,407,743...14,411,428
Ensembl chr10:13,903,224...13,906,969
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G |
Nucb2 |
nucleobindin 2 |
increases expression |
ISO |
Zearalenone results in increased expression of NUCB2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:170,750,877...170,787,353
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G |
Nudcd2 |
NudC domain containing 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NUDCD2 protein |
CTD |
PMID:36252740 |
|
NCBI chr10:25,163,247...25,168,738
Ensembl chr10:25,163,220...25,168,738
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G |
Nudt5 |
nudix hydrolase 5 |
decreases expression |
ISO |
Zearalenone results in decreased expression of NUDT5 protein |
CTD |
PMID:36252740 |
|
NCBI chr17:77,345,041...77,368,308
Ensembl chr17:72,435,697...72,459,001
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G |
Nxnl2 |
nucleoredoxin-like 2 |
increases expression |
ISO |
Zearalenone results in increased expression of NXNL2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr17:14,031,151...14,035,897
Ensembl chr17:14,031,153...14,036,189
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G |
Odaph |
odontogenesis associated phosphoprotein |
decreases expression |
ISO |
Zearalenone results in decreased expression of ODAPH mRNA |
CTD |
PMID:36828454 |
|
NCBI chr14:16,071,835...16,080,151
Ensembl chr14:16,073,058...16,080,129
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G |
Olfm1 |
olfactomedin 1 |
increases expression |
ISO |
Zearalenone results in increased expression of OLFM1 mRNA |
CTD |
PMID:19371625 PMID:36828454 |
|
NCBI chr 3:31,918,512...31,956,261
Ensembl chr 3:11,520,729...11,558,239
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G |
Olfml3 |
olfactomedin-like 3 |
increases expression |
ISO |
Zearalenone results in increased expression of OLFML3 mRNA |
CTD |
PMID:19371625 PMID:36828454 |
|
NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
multiple interactions increases expression |
ISO |
[Zearalenone co-treated with ochratoxin A] results in increased expression of OSGIN1 mRNA Zearalenone results in increased expression of OSGIN1 mRNA |
CTD |
PMID:34015425 |
|
NCBI chr19:64,380,336...64,409,165
Ensembl chr19:47,492,171...47,500,516
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G |
Oxsr1 |
oxidative stress responsive kinase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of OXSR1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 8:127,850,481...127,941,518
Ensembl chr 8:118,972,754...119,062,027
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G |
P4hb |
prolyl 4-hydroxylase subunit beta |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of P4HB protein |
CTD |
PMID:25058043 |
|
NCBI chr10:106,335,300...106,346,911
Ensembl chr10:105,836,982...105,848,500
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G |
Pafah1b2 |
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PAFAH1B2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 8:55,156,778...55,208,800
Ensembl chr 8:46,261,064...46,279,833
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G |
Pafah1b3 |
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PAFAH1B3 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:90,009,085...90,011,611
Ensembl chr 1:80,881,309...80,883,893
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G |
Paics |
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase |
decreases expression |
ISO |
Zearalenone results in decreased expression of PAICS protein |
CTD |
PMID:25058043 |
|
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,173,541...31,232,635
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G |
Pak2 |
p21 (RAC1) activated kinase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PAK2 protein |
CTD |
PMID:36252740 |
|
NCBI chr11:82,212,896...82,273,803
Ensembl chr11:68,707,969...68,768,816
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G |
Palm3 |
paralemmin 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PALM3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr19:41,026,757...41,035,217
Ensembl chr19:24,122,239...24,130,448
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage decreases expression increases expression multiple interactions |
EXP ISO |
Zearalenone results in increased cleavage of PARP1 protein Zearalenone results in decreased expression of PARP1 protein Zearalenone results in increased expression of PARP1 mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PARP1 mRNA] |
CTD |
PMID:24530352 PMID:28089945 PMID:38159578 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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G |
Pbdc1 |
polysaccharide biosynthesis domain containing 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PBDC1 protein |
CTD |
PMID:36252740 |
|
NCBI chr X:74,219,713...74,275,954
Ensembl chr X:70,154,106...70,184,552
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G |
Pc |
pyruvate carboxylase |
increases expression decreases expression |
ISO EXP |
Zearalenone results in increased expression of PCX protein Zearalenone results in decreased expression of PC mRNA; Zearalenone results in decreased expression of PC protein |
CTD |
PMID:25058043 PMID:32858132 |
|
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:201,804,267...201,898,380
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
Zearalenone results in increased expression of PCK2 protein |
CTD |
PMID:25058043 |
|
NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283
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G |
Pclaf |
PCNA clamp associated factor |
decreases expression |
ISO |
Zearalenone results in decreased expression of PCLAF mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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G |
Pdcd1 |
programmed cell death 1 |
increases expression |
ISO |
Zearalenone results in increased expression of PDCD1 mRNA |
CTD |
PMID:27757495 |
|
NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:94,418,791...94,431,937
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G |
Pdcd6ip |
programmed cell death 6 interacting protein |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in increased expression of PDCD6IP protein |
CTD |
PMID:25058043 |
|
NCBI chr 8:122,469,223...122,524,993
Ensembl chr 8:113,590,998...113,646,773
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G |
Pdcd7 |
programmed cell death 7 |
increases expression |
ISO |
Zearalenone results in increased expression of PDCD7 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 8:65,862,606...65,877,333
Ensembl chr 8:65,862,387...65,877,333
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G |
Pde3b |
phosphodiesterase 3B |
increases expression |
ISO |
Zearalenone results in increased expression of PDE3B mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 1:178,041,207...178,204,503
Ensembl chr 1:168,607,022...168,769,334
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G |
Pdgfrl |
platelet-derived growth factor receptor-like |
increases expression |
ISO |
Zearalenone results in increased expression of PDGFRL mRNA |
CTD |
PMID:36828454 |
|
NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
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G |
Pdha1 |
pyruvate dehydrogenase E1 subunit alpha 1 |
increases expression |
ISO |
Zearalenone results in increased expression of PDHA1 protein |
CTD |
PMID:25058043 |
|
NCBI chr X:38,509,158...38,522,986
Ensembl chr X:34,700,409...34,714,311
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|
G |
Pdxdc1 |
pyridoxal-dependent decarboxylase domain containing 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PDXDC1 protein |
CTD |
PMID:36252740 |
|
NCBI chr10:2,528,989...2,620,669
Ensembl chr10:2,025,360...2,113,520
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|
G |
Pfkfb2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PFKFB2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr13:44,683,499...44,727,135
Ensembl chr13:42,147,478...42,174,699
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G |
Pfkl |
phosphofructokinase, liver type |
decreases expression |
ISO |
Zearalenone results in decreased expression of PFKL protein |
CTD |
PMID:36252740 |
|
NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,664,272...10,686,315
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G |
Pgd |
phosphogluconate dehydrogenase |
decreases expression |
ISO |
Zearalenone results in decreased expression of PGD protein |
CTD |
PMID:25058043 |
|
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:159,561,271...159,742,778
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G |
Pgk1 |
phosphoglycerate kinase 1 |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of PGK1 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of PGK1 protein] |
CTD |
PMID:25058043 PMID:36252740 PMID:38159578 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:71,271,440...71,287,418
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|
G |
Pgpep1 |
pyroglutamyl-peptidase I |
decreases expression |
ISO |
Zearalenone results in decreased expression of PGPEP1 protein |
CTD |
PMID:36252740 |
|
NCBI chr16:18,804,408...18,817,466
Ensembl chr16:18,771,021...18,783,478
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|
G |
Pgr |
progesterone receptor |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of PGR mRNA; Zearalenone results in increased expression of PGR protein deoxynivalenol promotes the reaction [Zearalenone results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Zearalenone results in increased expression of PGR protein]; PPARG inhibits the reaction [Zearalenone results in increased expression of PGR mRNA]; Zearalenone inhibits the reaction [Progesterone binds to and results in increased activity of PGR protein] |
CTD |
PMID:19371625 PMID:21803136 PMID:28807876 PMID:28965971 PMID:35588983 |
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
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G |
Phb1 |
prohibitin 1 |
increases expression |
ISO |
Zearalenone results in increased expression of PHB1 protein |
CTD |
PMID:25058043 |
|
NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042
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|
G |
Phb2 |
prohibitin 2 |
increases expression |
ISO |
Zearalenone results in increased expression of PHB2 protein |
CTD |
PMID:25058043 |
|
NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:157,517,577...157,522,272
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|
G |
Phf11 |
PHD finger protein 11 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PHF11 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr15:37,568,090...37,592,490
Ensembl chr15:33,390,292...33,413,009
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|
G |
Phgdh |
phosphoglycerate dehydrogenase |
multiple interactions decreases expression |
ISO |
[Zearalenone co-treated with CGA protein] results in increased expression of PHGDH protein Zearalenone results in decreased expression of PHGDH protein |
CTD |
PMID:25058043 PMID:36252740 |
|
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:185,906,966...185,935,944
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|
G |
Pik3cd |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
increases expression |
ISO |
Zearalenone results in increased expression of PIK3CD mRNA |
CTD |
PMID:30138655 |
|
NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:160,094,952...160,120,930
|
|
G |
Pim1 |
Pim-1 proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Zearalenone results in increased expression of PIM1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,554,921...7,559,174
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G |
Pipox |
pipecolic acid and sarcosine oxidase |
increases expression |
ISO |
Zearalenone results in increased expression of PIPOX mRNA |
CTD |
PMID:36828454 |
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NCBI chr10:62,769,874...62,783,484
Ensembl chr10:62,769,900...62,782,370
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G |
Piwil1 |
piwi-like RNA-mediated gene silencing 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PIWIL1 protein |
CTD |
PMID:31419471 |
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NCBI chr12:33,585,747...33,606,715
Ensembl chr12:27,949,744...27,970,580
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G |
Pkdcc |
protein kinase domain containing, cytoplasmic |
increases expression |
ISO |
Zearalenone results in increased expression of PKDCC mRNA |
CTD |
PMID:36828454 |
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NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:11,455,686...11,465,556
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Zearalenone results in increased expression of PLAT mRNA |
CTD |
PMID:36828454 |
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NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223
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G |
Plcb1 |
phospholipase C beta 1 |
increases expression |
ISO |
Zearalenone results in increased expression of PLCB1 mRNA |
CTD |
PMID:19371625 PMID:36828454 |
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NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869
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G |
Plch1 |
phospholipase C, eta 1 |
increases expression |
ISO |
Zearalenone results in increased expression of PLCH1 protein |
CTD |
PMID:36252740 |
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NCBI chr 2:150,298,547...150,514,120
Ensembl chr 2:148,148,921...148,364,097
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G |
Plg |
plasminogen |
increases expression |
ISO |
Zearalenone results in increased expression of PLG mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Zearalenone results in increased expression of PLIN1 protein |
CTD |
PMID:25058043 |
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NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:133,664,892...133,676,828
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G |
Plppr2 |
phospholipid phosphatase related 2 |
increases expression |
ISO |
Zearalenone results in increased expression of PLPPR2 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 8:20,467,071...20,479,474
Ensembl chr 8:20,467,071...20,479,474
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G |
Plxdc2 |
plexin domain containing 2 |
increases expression |
ISO |
Zearalenone results in increased expression of PLXDC2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr17:79,169,238...79,594,279
Ensembl chr17:79,196,369...79,585,282
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G |
Pmm2 |
phosphomannomutase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PMM2 protein |
CTD |
PMID:36252740 |
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NCBI chr10:7,468,371...7,489,574
Ensembl chr10:6,961,709...6,983,098
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G |
Pnpla2 |
patatin-like phospholipase domain containing 2 |
multiple interactions increases expression |
ISO |
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PNPLA2 protein] |
CTD |
PMID:38159578 |
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NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:196,552,723...196,557,805
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G |
Polr2c |
RNA polymerase II subunit C |
increases expression |
ISO |
Zearalenone results in increased expression of POLR2C mRNA |
CTD |
PMID:19371625 |
|
NCBI chr19:10,164,148...10,170,930
Ensembl chr19:10,157,823...10,164,945
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G |
Pou2f3 |
POU class 2 homeobox 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of POU2F3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 8:52,392,363...52,474,756
Ensembl chr 8:43,495,527...43,577,795
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G |
Ppa1 |
inorganic pyrophosphatase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PPA1 protein |
CTD |
PMID:36252740 |
|
NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression |
ISO |
Zearalenone results in increased expression of PPARA mRNA |
CTD |
PMID:32119988 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of PPARD mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PPARD mRNA] |
CTD |
PMID:38159578 |
|
NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases activity increases expression decreases methylation multiple interactions |
ISO |
Zearalenone results in decreased activity of PPARG protein Zearalenone results in increased expression of PPARG mRNA; Zearalenone results in increased expression of PPARG protein Zearalenone results in decreased methylation of PPARG promoter PPARG inhibits the reaction [Zearalenone results in increased expression of PGR mRNA]; PPARG inhibits the reaction [Zearalenone results in increased expression of TFF1 mRNA] Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PPARG mRNA] |
CTD |
PMID:27481073 PMID:32119988 PMID:35588983 PMID:38159578 |
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NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1b |
PPARG coactivator 1 beta |
increases expression |
ISO |
Zearalenone results in increased expression of PPARGC1B mRNA |
CTD |
PMID:36828454 |
|
NCBI chr18:57,029,264...57,131,466
Ensembl chr18:54,758,902...54,861,194
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G |
Ppp1r1a |
protein phosphatase 1, regulatory (inhibitor) subunit 1A |
increases expression |
ISO |
Zearalenone results in increased expression of PPP1R1A mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 7:136,533,031...136,540,687
Ensembl chr 7:134,654,579...134,662,230
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G |
Prdm14 |
PR/SET domain 14 |
increases expression |
ISO |
Zearalenone results in increased expression of PRDM14 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:10,864,137...10,876,666
Ensembl chr 5:6,082,442...6,092,712
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G |
Prep |
prolyl endopeptidase |
decreases expression |
ISO |
Zearalenone results in decreased expression of PREP protein |
CTD |
PMID:25058043 |
|
NCBI chr20:50,138,588...50,235,549
Ensembl chr20:48,556,280...48,654,466
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G |
Prh1 |
proline rich protein HaeIII subfamily 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of PRH1 mRNA |
CTD |
PMID:17557909 |
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NCBI chr 4:166,543,755...166,547,614
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
increases expression |
ISO |
Zearalenone results in increased expression of PRKAA2 mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkar2a |
protein kinase cAMP-dependent type II regulatory subunit alpha |
increases expression |
ISO |
Zearalenone results in increased expression of PRKAR2A mRNA |
CTD |
PMID:19371625 |
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NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:109,395,833...109,455,628
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G |
Prmt6 |
protein arginine methyltransferase 6 |
increases expression |
ISO |
Zearalenone results in increased expression of PRMT6 mRNA |
CTD |
PMID:32119988 |
|
NCBI chr 2:200,615,780...200,620,790
Ensembl chr 2:197,927,220...197,933,648
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G |
Prps2 |
phosphoribosyl pyrophosphate synthetase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PRPS2 protein |
CTD |
PMID:36252740 |
|
NCBI chr X:26,975,915...27,013,184
Ensembl chr X:26,976,061...27,013,181
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G |
Prss23 |
serine protease 23 |
increases expression |
ISO |
Zearalenone results in increased expression of PRSS23 mRNA |
CTD |
PMID:22494775 |
|
NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:143,401,396...143,422,091
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G |
Prune1 |
prune exopolyphosphatase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PRUNE1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 2:182,830,575...182,859,972
Ensembl chr 2:182,830,578...182,859,336
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G |
Psmc1 |
proteasome 26S subunit, ATPase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMC1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
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G |
Psmc2 |
proteasome 26S subunit, ATPase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMC2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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G |
Psmc3 |
proteasome 26S subunit, ATPase 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMC3 protein |
CTD |
PMID:36252740 |
|
NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:77,031,825...77,043,358
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G |
Psmc4 |
proteasome 26S subunit, ATPase 4 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMC4 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:83,348,592...83,357,494
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G |
Psmd13 |
proteasome 26S subunit, non-ATPase 13 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMD13 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:205,394,248...205,406,525
Ensembl chr 1:195,964,138...195,976,905
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G |
Psmd2 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMD2 protein |
CTD |
PMID:36252740 |
|
NCBI chr11:93,752,761...93,763,388
Ensembl chr11:80,248,364...80,259,043
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G |
Psmg2 |
proteasome assembly chaperone 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PSMG2 protein |
CTD |
PMID:36252740 |
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NCBI chr18:63,478,620...63,493,193
Ensembl chr18:61,208,678...61,259,816
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G |
Pten |
phosphatase and tensin homolog |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of PTEN mRNA Zearalenone results in decreased expression of PTEN protein |
CTD |
PMID:27473017 PMID:30717214 |
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NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptges3 |
prostaglandin E synthase 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PTGES3 protein |
CTD |
PMID:36252740 |
|
NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:490,656...508,084
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G |
Ptgr2 |
prostaglandin reductase 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of PTGR2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 6:109,662,469...109,694,232
Ensembl chr 6:103,931,409...103,963,111
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
Zearalenone results in increased expression of PTGS2 mRNA |
CTD |
PMID:27757495 PMID:36828454 |
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NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
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G |
Ptk2 |
protein tyrosine kinase 2 |
decreases expression |
ISO EXP |
Zearalenone results in decreased expression of PTK2 protein |
CTD |
PMID:36288102 |
|
NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783
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G |
Pus7 |
pseudouridine synthase 7 |
increases expression |
ISO |
Zearalenone results in increased expression of PUS7 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 4:12,252,553...12,293,547
Ensembl chr 4:11,360,188...11,401,172
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G |
Pycard |
PYD and CARD domain containing |
increases expression multiple interactions |
ISO EXP |
Zearalenone results in increased expression of PYCARD mRNA; Zearalenone results in increased expression of PYCARD protein [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD protein] [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of PYCARD protein |
CTD |
PMID:30270565 PMID:31586597 |
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NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955
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G |
Rab20 |
RAB20, member RAS oncogene family |
decreases expression |
ISO |
Zearalenone results in decreased expression of RAB20 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr16:84,721,427...84,745,610
Ensembl chr16:78,019,337...78,043,529
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G |
Rack1 |
receptor for activated C kinase 1 |
increases expression |
ISO |
Zearalenone results in increased expression of RACK1 mRNA; Zearalenone results in increased expression of RACK1 protein |
CTD |
PMID:32328699 |
|
NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975
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G |
Rad51 |
RAD51 recombinase |
decreases expression increases expression |
ISO |
Zearalenone results in decreased expression of RAD51 mRNA Zearalenone results in increased expression of RAD51 mRNA; Zearalenone results in increased expression of RAD51 protein |
CTD |
PMID:27862621 PMID:28552778 PMID:35650142 |
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NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:106,100,381...106,125,035
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Zearalenone results in increased expression of RAF1 mRNA |
CTD |
PMID:29758222 |
|
NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317
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G |
Ranbp1 |
RAN binding protein 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RANBP1 protein |
CTD |
PMID:36252740 |
|
NCBI chr11:96,246,912...96,255,145
Ensembl chr11:82,742,600...82,750,838
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G |
Rap1a |
RAP1A, member of RAS oncogene family |
decreases expression |
ISO |
Zearalenone results in decreased expression of RAP1A mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:193,208,635...193,286,501
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G |
Rap1b |
RAP1B, member of RAS oncogene family |
decreases expression |
ISO |
Zearalenone results in decreased expression of RAP1B mRNA |
CTD |
PMID:30717214 |
|
NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:53,423,130...53,456,370
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G |
Rapgef4 |
Rap guanine nucleotide exchange factor 4 |
increases expression |
ISO |
Zearalenone results in increased expression of RAPGEF4 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:56,809,270...57,102,316
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G |
Rarb |
retinoic acid receptor, beta |
decreases expression |
ISO |
Zearalenone results in decreased expression of RARB mRNA |
CTD |
PMID:28965971 |
|
NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288
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G |
Rars1 |
arginyl-tRNA synthetase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RARS1 protein |
CTD |
PMID:25058043 |
|
NCBI chr10:20,774,804...20,799,251
Ensembl chr10:20,270,483...20,295,196
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G |
Rasgrp1 |
RAS guanyl releasing protein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of RASGRP1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:104,170,013...104,230,056
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G |
Rassf1 |
Ras association domain family member 1 |
increases expression |
ISO |
Zearalenone results in increased expression of RASSF1 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:108,225,023...108,236,164
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G |
Rassf2 |
Ras association domain family member 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RASSF2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:119,245,821...119,280,431
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G |
Rbbp8 |
RB binding protein 8, endonuclease |
increases expression |
ISO |
Zearalenone results in increased expression of RBBP8 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr18:3,198,188...3,263,643
Ensembl chr18:2,921,286...2,988,846
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G |
Rbbp8nl |
RBBP8 N-terminal like |
decreases expression |
ISO |
Zearalenone results in decreased expression of RBBP8NL mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:167,364,048...167,378,993
Ensembl chr 3:167,364,048...167,379,092
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G |
Rbm24 |
RNA binding motif protein 24 |
increases expression |
ISO |
Zearalenone results in increased expression of RBM24 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr17:18,481,893...18,494,440
Ensembl chr17:18,275,688...18,288,102
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G |
Rbp1 |
retinol binding protein 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RBP1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:99,025,206...99,046,743
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G |
Rel |
REL proto-oncogene, NF-kB subunit |
decreases expression |
ISO |
Zearalenone results in decreased expression of REL protein |
CTD |
PMID:36252740 |
|
NCBI chr14:101,891,238...101,922,324
Ensembl chr14:97,695,161...97,720,892
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation |
EXP ISO |
3-methyladenine promotes the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; Sirolimus inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]; Zearalenone results in increased phosphorylation of and affects the localization of RELA protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of RELA protein]]; corynoline inhibits the reaction [Zearalenone results in increased phosphorylation of RELA protein] |
CTD |
PMID:31586597 PMID:36161741 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
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G |
Rfk |
riboflavin kinase |
decreases expression |
ISO |
Zearalenone results in decreased expression of RFK protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:224,226,632...224,234,185
Ensembl chr 1:214,799,825...214,807,438 Ensembl chr X:214,799,825...214,807,438
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|
G |
Rhobtb1 |
Rho-related BTB domain containing 1 |
increases expression |
ISO |
Zearalenone results in increased expression of RHOBTB1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr20:19,326,197...19,455,182
Ensembl chr20:19,327,155...19,403,012
|
|
G |
Ribc2 |
RIB43A domain with coiled-coils 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RIBC2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 7:116,242,863...116,257,868
Ensembl chr 7:116,242,863...116,257,863
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G |
Rims4 |
regulating synaptic membrane exocytosis 4 |
increases expression |
ISO |
Zearalenone results in increased expression of RIMS4 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:172,940,404...173,004,490
Ensembl chr 3:152,524,095...152,584,780
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of RIPK1 mRNA; Zearalenone results in increased expression of RIPK1 protein RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]; scutellarin affects the reaction [RIPK1 protein affects the reaction [Zearalenone results in increased cleavage of CASP3 protein]]; scutellarin inhibits the reaction [Zearalenone results in increased expression of RIPK1 mRNA]; scutellarin inhibits the reaction [Zearalenone results in increased expression of RIPK1 protein] |
CTD |
PMID:36252740 |
|
NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824
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G |
Rmi2 |
RecQ mediated genome instability 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RMI2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:5,336,269...5,344,202
Ensembl chr10:4,830,553...4,837,235
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|
G |
Rnf224 |
ring finger protein 224 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RNF224 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 3:8,050,088...8,052,416
Ensembl chr 3:8,051,475...8,051,945
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G |
Rnh1 |
ribonuclease/angiogenin inhibitor 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RNH1 protein |
CTD |
PMID:25058043 PMID:36252740 |
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NCBI chr 1:196,269,293...196,281,763
Ensembl chr 1:196,269,293...196,281,910
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G |
Rpa3 |
replication protein A3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPA3 protein |
CTD |
PMID:36252740 |
|
NCBI chr 4:37,270,966...37,273,997
Ensembl chr 4:36,304,651...36,307,709
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G |
Rpl14 |
ribosomal protein L14 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPL14 mRNA |
CTD |
PMID:30138655 |
|
NCBI chr 8:129,163,620...129,166,745
Ensembl chr 8:120,284,645...120,289,064
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G |
Rpl23a |
ribosomal protein L23A |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPL23A mRNA |
CTD |
PMID:30138655 |
|
NCBI chr10:63,574,732...63,577,511
Ensembl chr10:63,076,066...63,079,346 Ensembl chr15:63,076,066...63,079,346
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G |
Rps23 |
ribosomal protein S23 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPS23 protein |
CTD |
PMID:36252740 |
|
NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918
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G |
Rps3 |
ribosomal protein S3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPS3 protein |
CTD |
PMID:35504548 |
|
NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:153,777,472...153,783,680
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G |
Rps5 |
ribosomal protein S5 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPS5 mRNA |
CTD |
PMID:30138655 |
|
NCBI chr 1:82,610,965...82,615,262
Ensembl chr 1:73,538,776...73,543,073
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G |
Rps6 |
ribosomal protein S6 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPS6 protein |
CTD |
PMID:36252740 |
|
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions decreases phosphorylation |
ISO |
2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; dorsomorphin inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]; HERPUD1 protein inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:30394307 PMID:31982503 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908
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G |
Rps8 |
ribosomal protein S8 |
decreases expression |
ISO |
Zearalenone results in decreased expression of RPS8 mRNA |
CTD |
PMID:30138655 |
|
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
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G |
Rragb |
Ras-related GTP binding B |
decreases expression |
ISO |
Zearalenone results in decreased expression of RRAGB mRNA |
CTD |
PMID:19371625 |
|
NCBI chr X:21,560,313...21,610,550
Ensembl chr X:18,184,992...18,234,639
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G |
Rrs1 |
ribosome biogenesis regulator 1 homolog |
increases expression |
ISO |
Zearalenone results in increased expression of RRS1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 5:14,516,303...14,517,936
Ensembl chr 5:9,733,091...9,735,140
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G |
Rubcnl |
rubicon like autophagy enhancer |
increases expression |
ISO |
Zearalenone results in increased expression of RUBCNL mRNA |
CTD |
PMID:36828454 |
|
NCBI chr15:56,741,897...56,807,086
Ensembl chr15:50,332,418...50,400,849
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G |
S100a6 |
S100 calcium binding protein A6 |
decreases expression |
ISO |
Zearalenone results in decreased expression of S100A6 protein |
CTD |
PMID:36252740 |
|
NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:176,100,899...176,102,180
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G |
S100g |
S100 calcium binding protein G |
increases expression |
EXP |
Zearalenone results in increased expression of S100G mRNA |
CTD |
PMID:17557909 |
|
NCBI chr X:35,337,636...35,340,205
Ensembl chr X:31,705,866...31,708,433
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G |
S1pr3 |
sphingosine-1-phosphate receptor 3 |
increases expression |
ISO |
Zearalenone results in increased expression of S1PR3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
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G |
Sae1 |
SUMO1 activating enzyme subunit 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SAE1 protein |
CTD |
PMID:36252740 |
|
NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986
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G |
Samm50 |
SAMM50 sorting and assembly machinery component |
increases expression |
ISO |
Zearalenone results in increased expression of SAMM50 protein |
CTD |
PMID:25058043 |
|
NCBI chr 7:115,317,472...115,341,682
Ensembl chr 7:115,317,404...115,341,682
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G |
Sar1a |
secretion associated, Ras related GTPase 1A |
decreases expression |
ISO |
Zearalenone results in decreased expression of SAR1A protein |
CTD |
PMID:36252740 |
|
NCBI chr20:30,166,310...30,178,718
Ensembl chr20:29,623,553...29,635,935
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SAT1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr X:44,008,089...44,011,376
Ensembl chr X:40,157,046...40,196,813
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G |
Scd |
stearoyl-CoA desaturase |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of SCD1 mRNA Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of SCD1 mRNA] |
CTD |
PMID:38159578 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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G |
Sec31a |
SEC31 homolog A, COPII coat complex component |
decreases expression |
ISO |
Zearalenone results in decreased expression of SEC31A protein |
CTD |
PMID:36252740 |
|
NCBI chr14:9,518,655...9,573,579
Ensembl chr14:9,214,349...9,269,273
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G |
Serbp1 |
Serpine1 mRNA binding protein 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SERBP1 protein |
CTD |
PMID:25058043 |
|
NCBI chr 4:97,731,200...97,748,438
Ensembl chr 4:96,401,477...96,421,813
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of SERPINE1 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
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G |
Sez6 |
seizure related 6 homolog |
increases expression |
ISO |
Zearalenone results in increased expression of SEZ6 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr10:63,317,065...63,366,733
Ensembl chr10:62,819,069...62,868,671
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G |
Sf3b5 |
splicing factor 3b, subunit 5 |
increases expression |
ISO |
Zearalenone results in increased expression of SF3B5 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:9,177,189...9,177,901
Ensembl chr 1:7,350,731...7,357,839
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G |
Sftpd |
surfactant protein D |
increases expression |
EXP |
Zearalenone results in increased expression of SFTPD mRNA |
CTD |
PMID:17557909 |
|
NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,046,483...17,059,927
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G |
Siah1 |
siah E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SIAH1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
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G |
Sirt1 |
sirtuin 1 |
decreases expression multiple interactions increases expression |
ISO |
Zearalenone results in decreased expression of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in decreased expression of SIRT1 protein]]; corynoline inhibits the reaction [Zearalenone results in decreased expression of SIRT1 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of SIRT1 mRNA] |
CTD |
PMID:36161741 PMID:38159578 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
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G |
Slc12a8 |
solute carrier family 12, member 8 |
multiple interactions decreases expression |
ISO |
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of SLC12A8 mRNA] |
CTD |
PMID:38159578 |
|
NCBI chr11:80,622,000...80,771,674
Ensembl chr11:67,116,877...67,266,834
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G |
Slc19a2 |
solute carrier family 19 member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC19A2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172
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G |
Slc1a5 |
solute carrier family 1 member 5 |
increases expression decreases expression |
ISO EXP |
Zearalenone results in increased expression of SLC1A5 mRNA Zearalenone results in decreased expression of SLC1A5 mRNA; Zearalenone results in decreased expression of SLC1A5 protein |
CTD |
PMID:19371625 PMID:32858132 |
|
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952
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G |
Slc22a3 |
solute carrier family 22 member 3 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC22A3 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:48,235,476...48,324,612
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G |
Slc26a9 |
solute carrier family 26 member 9 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SLC26A9 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr13:45,730,022...45,757,662
Ensembl chr13:43,177,867...43,204,330
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G |
Slc2a2 |
solute carrier family 2 member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC2A2 mRNA |
CTD |
PMID:32119988 |
|
NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc31a1 |
solute carrier family 31 member 1 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC31A1 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 5:80,830,574...80,859,810
Ensembl chr 5:75,814,743...75,844,228
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G |
Slc37a2 |
solute carrier family 37 member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC37A2 protein |
CTD |
PMID:36252740 |
|
NCBI chr 8:45,134,596...45,160,551
Ensembl chr 8:36,946,930...36,971,482
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G |
Slc38a1 |
solute carrier family 38, member 1 |
decreases expression |
EXP |
Zearalenone results in decreased expression of SLC38A1 mRNA; Zearalenone results in decreased expression of SLC38A1 protein |
CTD |
PMID:32858132 |
|
NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
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G |
Slc39a6 |
solute carrier family 39 member 6 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC39A6 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr18:16,139,621...16,160,163
Ensembl chr18:15,864,875...15,885,417
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G |
Slc3a2 |
solute carrier family 3 member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC3A2 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc41a3 |
solute carrier family 41, member 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SLC41A3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 4:123,109,555...123,154,766
Ensembl chr 4:123,112,748...123,154,766
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G |
Slc6a15 |
solute carrier family 6 member 15 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC6A15 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239
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G |
Slc6a6 |
solute carrier family 6 member 6 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC6A6 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC7A11 mRNA |
CTD |
PMID:25424538 |
|
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536
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G |
Slc7a2 |
solute carrier family 7 member 2 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC7A2 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
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G |
Slc7a5 |
solute carrier family 7 member 5 |
increases expression |
ISO |
Zearalenone results in increased expression of SLC7A5 mRNA |
CTD |
PMID:19371625 PMID:36828454 |
|
NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823
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G |
Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
decreases activity |
ISO |
Zearalenone results in decreased activity of SLCO1A2 protein |
CTD |
PMID:38341109 |
|
NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:174,710,004...175,254,573
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G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
decreases activity |
ISO |
Zearalenone results in decreased activity of SLCO1B3 protein |
CTD |
PMID:38341109 |
|
NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:174,551,480...174,619,981
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G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
decreases activity |
ISO |
Zearalenone results in decreased activity of SLCO2B1 protein |
CTD |
PMID:38341109 |
|
NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:153,959,293...154,007,353
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G |
Slit2 |
slit guidance ligand 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SLIT2 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948
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G |
Slitrk4 |
SLIT and NTRK-like family, member 4 |
increases expression |
ISO |
Zearalenone results in increased expression of SLITRK4 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr X:147,728,163...147,755,086
Ensembl chr X:142,706,338...142,718,575
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G |
Smad3 |
SMAD family member 3 |
increases expression multiple interactions |
ISO |
Zearalenone results in increased expression of SMAD3 mRNA [Tamoxifen co-treated with Zearalenone] results in increased expression of SMAD3 mRNA |
CTD |
PMID:30138655 |
|
NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960
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G |
Smpdl3b |
sphingomyelin phosphodiesterase, acid-like 3B |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of SMPDL3B protein |
CTD |
PMID:25058043 |
|
NCBI chr 5:150,228,607...150,250,688
Ensembl chr 5:144,944,636...144,966,720
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G |
Snai2 |
snail family transcriptional repressor 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SNAI2 mRNA |
CTD |
PMID:28965971 |
|
NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200
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G |
Sod1 |
superoxide dismutase 1 |
decreases expression multiple interactions |
EXP ISO |
Zearalenone results in decreased expression of SOD1 mRNA; Zearalenone results in decreased expression of SOD1 protein Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of SOD1 protein] |
CTD |
PMID:32858132 PMID:38159578 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
decreases expression multiple interactions |
EXP ISO |
Zearalenone results in decreased expression of SOD2 mRNA; Zearalenone results in decreased expression of SOD2 protein [Nicotinamide Mononucleotide co-treated with Zearalenone] results in decreased expression of SOD2 mRNA |
CTD |
PMID:32858132 PMID:38159578 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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G |
Sohlh2 |
spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SOHLH2 mRNA |
CTD |
PMID:28089945 |
|
NCBI chr 2:141,512,410...141,534,864
Ensembl chr 2:139,362,246...139,384,699
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G |
Sox9 |
SRY-box transcription factor 9 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SOX9 mRNA |
CTD |
PMID:24412631 |
|
NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994
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G |
Spata2 |
spermatogenesis associated 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SPATA2 mRNA |
CTD |
PMID:24412631 |
|
NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705
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G |
Spsb3 |
splA/ryanodine receptor domain and SOCS box containing 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SPSB3 mRNA |
CTD |
PMID:19371625 |
|
NCBI chr10:14,411,692...14,417,357
Ensembl chr10:13,907,253...13,912,841
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G |
Sqle |
squalene epoxidase |
decreases expression |
ISO |
Zearalenone results in decreased expression of SQLE mRNA |
CTD |
PMID:19371625 PMID:25424538 |
|
NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618
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G |
Sqstm1 |
sequestosome 1 |
increases expression decreases expression |
EXP ISO |
Zearalenone results in increased expression of SQSTM1 protein Zearalenone results in decreased expression of SQSTM1 mRNA; Zearalenone results in decreased expression of SQSTM1 protein |
CTD |
PMID:31586597 PMID:31982503 PMID:32858132 PMID:34537261 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
decreases expression decreases activity |
EXP |
Zearalenone results in decreased expression of SRD5A1 mRNA Zearalenone results in decreased activity of SRD5A1 protein |
CTD |
PMID:29669061 |
|
NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
ISO |
Zearalenone results in increased expression of SREBF1 mRNA |
CTD |
PMID:38159578 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
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G |
Srxn1 |
sulfiredoxin 1 |
decreases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of SRXN1 mRNA [Plant Extracts co-treated with Zearalenone] results in decreased expression of SRXN1 mRNA; [Zearalenone co-treated with ochratoxin A] results in decreased expression of SRXN1 mRNA |
CTD |
PMID:34015425 |
|
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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G |
Ssc4d |
scavenger receptor cysteine rich family member with 4 domains |
decreases expression |
ISO |
Zearalenone results in decreased expression of SSC4D mRNA |
CTD |
PMID:19371625 |
|
NCBI chr12:20,702,931...20,723,732
Ensembl chr12:20,702,950...20,718,706
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G |
Ssu72 |
SSU72 homolog, RNA polymerase II CTD phosphatase |
decreases expression |
ISO |
Zearalenone results in decreased expression of SSU72 protein |
CTD |
PMID:36252740 |
|
NCBI chr 5:171,595,919...171,625,675
Ensembl chr 5:166,313,650...166,343,429
|
|
G |
St8sia1 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of ST8SIA1 mRNA |
CTD |
PMID:36828454 |
|
NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions increases expression decreases expression |
ISO EXP |
Colforsin affects the reaction [Zearalenone results in increased expression of STAR mRNA] Zearalenone results in decreased expression of STAR mRNA; Zearalenone results in decreased expression of STAR protein |
CTD |
PMID:24512812 PMID:26783879 PMID:29627501 |
|
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672
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Stat5a |
signal transducer and activator of transcription 5A |
decreases expression |
ISO |
Zearalenone results in decreased expression of STAT5A mRNA |
CTD |
PMID:30138655 |
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NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
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Stk31 |
serine threonine kinase 31 |
decreases expression |
ISO |
Zearalenone results in decreased expression of STK31 protein |
CTD |
PMID:31419471 |
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NCBI chr 4:78,370,691...78,467,599
Ensembl chr 4:78,370,649...78,466,240
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Stoml2 |
stomatin like 2 |
increases expression |
ISO |
Zearalenone results in increased expression of STOML2 protein |
CTD |
PMID:25058043 |
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NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920
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Stra8 |
stimulated by retinoic acid 8 |
decreases expression |
ISO |
Zearalenone results in decreased expression of STRA8 mRNA |
CTD |
PMID:28552778 |
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NCBI chr 4:63,601,443...63,624,777
Ensembl chr 4:63,601,604...63,624,771
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Strap |
serine/threonine kinase receptor associated protein |
decreases expression |
ISO |
Zearalenone results in decreased expression of STRAP protein |
CTD |
PMID:36252740 |
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NCBI chr 4:172,377,325...172,391,573
Ensembl chr 4:170,646,001...170,660,828
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Sult1e1 |
sulfotransferase family 1E member 1 |
decreases activity |
ISO |
Zearalenone results in decreased activity of SULT1E1 protein |
CTD |
PMID:16914110 |
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NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,422,324...20,439,275
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Syap1 |
synapse associated protein 1 |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in decreased expression of SYAP1 protein |
CTD |
PMID:25058043 |
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NCBI chr X:31,792,180...31,826,672
Ensembl chr X:31,792,193...31,826,667
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Sycp1 |
synaptonemal complex protein 1 |
increases expression |
ISO |
Zearalenone results in increased expression of SYCP1 mRNA |
CTD |
PMID:24412631 |
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NCBI chr 2:192,985,164...193,145,234
Ensembl chr 2:190,296,954...190,456,737
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Sycp3 |
synaptonemal complex protein 3 |
decreases expression |
ISO |
Zearalenone results in decreased expression of SYCP3 mRNA; Zearalenone results in decreased expression of SYCP3 protein |
CTD |
PMID:24412631 PMID:28552778 PMID:31419471 |
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NCBI chr 7:24,761,476...24,775,933
Ensembl chr 7:22,874,055...22,888,511
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Syncrip |
synaptotagmin binding, cytoplasmic RNA interacting protein |
decreases expression |
ISO |
Zearalenone results in decreased expression of SYNCRIP protein |
CTD |
PMID:36252740 |
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NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:89,402,866...89,435,515
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Taldo1 |
transaldolase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TALDO1 protein |
CTD |
PMID:25058043 |
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NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
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Tbcel |
tubulin folding cofactor E-like |
decreases expression |
ISO |
Zearalenone results in decreased expression of TBCEL protein |
CTD |
PMID:36252740 |
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NCBI chr 8:42,795,648...42,854,552
Ensembl chr 8:42,796,730...42,854,552
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Tead3 |
TEA domain transcription factor 3 |
increases expression |
ISO |
Zearalenone results in increased expression of TEAD3 mRNA |
CTD |
PMID:30138655 |
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NCBI chr20:6,393,786...6,413,177
Ensembl chr20:6,392,053...6,411,446
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Tf |
transferrin |
decreases expression multiple interactions affects expression |
ISO |
Zearalenone results in decreased expression of TF mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of TF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TF mRNA Zearalenone affects the expression of TF mRNA |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511
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Tfap4 |
transcription factor AP-4 |
increases expression |
ISO |
Zearalenone results in increased expression of TFAP4 mRNA |
CTD |
PMID:36828454 |
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NCBI chr10:11,507,242...11,525,794
Ensembl chr10:11,002,911...11,019,386
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Tff1 |
trefoil factor 1 |
multiple interactions increases expression |
ISO |
deoxynivalenol promotes the reaction [Zearalenone results in increased expression of TFF1 mRNA]; PPARG inhibits the reaction [Zearalenone results in increased expression of TFF1 mRNA] |
CTD |
PMID:35588983 |
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NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,235,736...9,239,597
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Tff3 |
trefoil factor 3 |
increases expression |
ISO |
Zearalenone results in increased expression of TFF3 mRNA |
CTD |
PMID:28965971 |
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NCBI chr20:9,194,623...9,199,333
Ensembl chr20:9,193,262...9,198,054
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Tgfa |
transforming growth factor alpha |
increases expression |
ISO |
Zearalenone results in increased expression of TGFA mRNA |
CTD |
PMID:19371625 |
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NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894
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Tgfb2 |
transforming growth factor, beta 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TGFB2 mRNA |
CTD |
PMID:27862621 PMID:29758222 |
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NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405
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Tgm1 |
transglutaminase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TGM1 mRNA |
CTD |
PMID:36828454 |
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NCBI chr15:33,160,985...33,175,632
Ensembl chr15:29,191,041...29,204,523
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Th |
tyrosine hydroxylase |
decreases expression |
ISO |
Zearalenone results in decreased expression of TH mRNA |
CTD |
PMID:24412706 |
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NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767
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Thbs1 |
thrombospondin 1 |
increases expression decreases expression |
ISO |
Zearalenone results in increased expression of THBS1 mRNA Zearalenone results in decreased expression of THBS1 mRNA |
CTD |
PMID:19371625 PMID:28965971 |
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NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440
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Thra |
thyroid hormone receptor alpha |
multiple interactions |
ISO |
Zearalenone binds to and results in increased activity of THRA protein |
CTD |
PMID:33049310 |
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NCBI chr10:84,198,141...84,225,659
Ensembl chr10:83,700,755...83,729,936
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Thrb |
thyroid hormone receptor beta |
multiple interactions decreases activity |
ISO |
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein; Zearalenone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] Zearalenone results in decreased activity of THRB protein |
CTD |
PMID:27481073 PMID:31077750 |
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NCBI chr15:10,115,954...10,465,231
Ensembl chr15:7,685,180...7,882,916
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Timm17a |
translocase of inner mitochondrial membrane 17A |
increases expression |
ISO |
Zearalenone results in increased expression of TIMM17A protein |
CTD |
PMID:36252740 |
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NCBI chr13:49,282,918...49,296,363
Ensembl chr13:46,730,660...46,742,655
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Tinf2 |
TERF1 interacting nuclear factor 2 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TINF2 mRNA |
CTD |
PMID:19371625 |
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NCBI chr15:33,140,611...33,146,930
Ensembl chr15:29,170,652...29,176,984
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Tkt |
transketolase |
decreases expression |
ISO |
Zearalenone results in decreased expression of TKT protein |
CTD |
PMID:25058043 |
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NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,723,762...5,748,698
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Tln1 |
talin 1 |
multiple interactions |
ISO |
[Zearalenone co-treated with CGA protein] results in increased expression of TLN1 protein |
CTD |
PMID:25058043 |
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NCBI chr 5:62,583,730...62,613,687
Ensembl chr 5:57,787,943...57,817,900
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Tlr3 |
toll-like receptor 3 |
increases expression |
ISO |
Zearalenone results in increased expression of TLR3 mRNA |
CTD |
PMID:27757495 |
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NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545
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Tm6sf1 |
transmembrane 6 superfamily member 1 |
increases expression |
ISO |
Zearalenone results in increased expression of TM6SF1 mRNA |
CTD |
PMID:25424538 |
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NCBI chr 1:145,209,052...145,237,725
Ensembl chr 1:135,786,381...135,828,443
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Tmem121 |
transmembrane protein 121 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TMEM121 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 6:132,262,182...132,265,797
Ensembl chr 6:132,262,176...132,265,914
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Tmem215 |
transmembrane protein 215 |
increases expression |
ISO |
Zearalenone results in increased expression of TMEM215 mRNA |
CTD |
PMID:36828454 |
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NCBI chr 5:55,612,568...55,615,828
Ensembl chr 5:55,612,568...55,615,828
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Tmem54 |
transmembrane protein 54 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TMEM54 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 5:141,449,191...141,455,683
Ensembl chr 5:141,449,191...141,455,682
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Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [corynoline inhibits the reaction [Zearalenone results in increased expression of TNF protein]]; corynoline inhibits the reaction [Zearalenone results in increased expression of TNF protein]; Lipopolysaccharides promotes the reaction [Zearalenone results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of TNF mRNA] Zearalenone results in increased expression of TNF; Zearalenone results in increased expression of TNF mRNA; Zearalenone results in increased expression of TNF protein 3-methyladenine promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; [Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein; Gallic Acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]; Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein] [Lipopolysaccharides co-treated with Zearalenone] results in increased secretion of TNF protein |
CTD |
PMID:16687389 PMID:25682699 PMID:31586597 PMID:32328699 PMID:34723416 PMID:36161741 PMID:38159578 More...
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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Tnfrsf25 |
TNF receptor superfamily member 25 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TNFRSF25 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 5:167,904,377...167,909,052
Ensembl chr 5:162,622,075...162,626,341
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Tnfsf10 |
TNF superfamily member 10 |
increases expression |
ISO |
Zearalenone results in increased expression of TNFSF10 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135
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Tnnt1 |
troponin T1, slow skeletal type |
decreases expression |
ISO |
Zearalenone results in decreased expression of TNNT1 mRNA |
CTD |
PMID:19371625 |
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NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
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Tomm40 |
translocase of outer mitochondrial membrane 40 |
increases expression |
ISO |
Zearalenone results in increased expression of TOMM40 protein |
CTD |
PMID:25058043 |
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NCBI chr 1:88,486,745...88,498,833
Ensembl chr 1:79,358,786...79,370,915
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Tomm70 |
translocase of outer mitochondrial membrane 70 |
increases expression |
ISO |
Zearalenone results in increased expression of TOMM70A protein |
CTD |
PMID:25058043 |
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NCBI chr11:56,847,837...56,886,302
Ensembl chr11:43,377,216...43,417,202
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Tp53 |
tumor protein p53 |
decreases expression increases expression multiple interactions |
ISO |
Zearalenone results in decreased expression of TRP53 mRNA; Zearalenone results in decreased expression of TRP53 protein Zearalenone results in increased expression of TP53 mRNA [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA] crocin inhibits the reaction [Zearalenone results in increased expression of TRP53 protein] |
CTD |
PMID:24412631 PMID:26231423 PMID:27473017 PMID:30668976 |
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NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
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Tp73 |
tumor protein p73 |
multiple interactions |
ISO |
[Zearalenone co-treated with Aflatoxin B1] results in increased expression of TP73 mRNA |
CTD |
PMID:28965971 |
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NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128
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G |
Tpi1 |
triosephosphate isomerase 1 |
decreases expression |
ISO |
Zearalenone results in decreased expression of TPI1 protein |
CTD |
PMID:36252740 |
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NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:157,615,386...157,619,541
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G |
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