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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:zaleplon
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Accession:CHEBI:10102 term browser browse the term
Definition:A pyrazolo[1,5-a]pyrimidine having a nitrile group at position 3 and a 3-(N-ethylacetamido)phenyl substituent at the 7-position.
Synonyms:exact_synonym: N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide
 related_synonym: 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide;   Formula=C17H15N5O;   InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3;   InChIKey=HUNXMJYCHXQEGX-UHFFFAOYSA-N;   SMILES=CCN(C(C)=O)c1cccc(c1)-c1ccnc2c(cnn12)C#N
 xref: Beilstein:8153844;   CAS:151319-34-5;   DrugBank:DB00962;   Drug_Central:2857;   KEGG:C07484;   KEGG:D00530;   LINCS:LSM-5971
 xref_mesh: MESH:C085665
 xref: Patent:US4626538;   Wikipedia:Zaleplon


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zaleplon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aox1 aldehyde oxidase 1 affects metabolic processing ISO AOX1 protein affects the metabolism of zaleplon CTD PMID:20444863 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression EXP zaleplon deficiency results in decreased expression of GABRA1 mRNA CTD PMID:11804615 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression EXP zaleplon deficiency results in increased expression of GABRA4 mRNA CTD PMID:11804615 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP zaleplon deficiency results in increased expression of GABRB1 mRNA CTD PMID:11804615 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP zaleplon deficiency results in decreased expression of GABRB2 mRNA CTD PMID:11804615 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP zaleplon deficiency results in decreased expression of GABRG2 mRNA CTD PMID:11804615 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      group 19831
        pseudohalo group 4581
          cyano group 4581
            nitrile 4581
              zaleplon 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteropolycyclic compound 18300
                                    organic heterobicyclic compound 17242
                                      pyrazolopyrimidine 5748
                                        zaleplon 6
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