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G |
Abcb1a |
ATP-binding cassette, sub-family B member 1A |
decreases response to substance multiple interactions |
ISO |
ABCB1 protein results in decreased susceptibility to deoxynivalenol deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]] |
CTD |
PMID:29174985 |
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NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
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G |
Abcc3 |
ATP-binding cassette, sub-family C member 3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ABCC3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
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G |
Abcf1 |
ATP-binding cassette, sub-family F member 1 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of ABCF1 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr17:36,267,711...36,280,642
Ensembl chr17:36,267,711...36,280,653
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G |
Abi1 |
abl interactor 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of ABI1 protein |
CTD |
PMID:23352502 |
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NCBI chr 2:22,830,085...22,930,207
Ensembl chr 2:22,830,085...22,930,253
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G |
Abraxas2 |
BRISC complex subunit |
increases expression |
ISO |
deoxynivalenol results in increased expression of ABRAXAS2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:132,460,954...132,486,843
Ensembl chr 7:132,460,954...132,486,840
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G |
Acan |
aggrecan |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ACAN mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
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G |
Acin1 |
apoptotic chromatin condensation inducer 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of ACIN1 protein |
CTD |
PMID:23811945 |
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NCBI chr14:54,879,618...54,924,422
Ensembl chr14:54,879,618...54,924,388
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ACSL4 protein |
CTD |
PMID:33890134 |
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NCBI chr X:141,100,989...141,173,792
Ensembl chr X:141,100,989...141,173,531
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G |
Acta1 |
actin alpha 1, skeletal muscle |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of ACTA1 protein |
CTD |
PMID:23811945 |
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NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490
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G |
Actbl2 |
actin, beta-like 2 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of ACTBL2 protein |
CTD |
PMID:23352502 |
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NCBI chr13:111,391,547...111,394,283
Ensembl chr13:111,391,547...111,394,283
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G |
Afg2b |
AFG2 AAA ATPase homolog B |
increases expression |
ISO |
deoxynivalenol results in increased expression of AFG2B mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:122,461,112...122,474,933
Ensembl chr 2:122,461,120...122,474,750
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G |
Agfg1 |
ArfGAP with FG repeats 1 |
affects phosphorylation increases expression |
EXP ISO |
deoxynivalenol affects the phosphorylation of AGFG1 protein deoxynivalenol results in increased expression of AGFG1 mRNA |
CTD |
PMID:23811945 PMID:31863870 |
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NCBI chr 1:82,816,738...82,878,722
Ensembl chr 1:82,817,204...82,878,903
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G |
Ahnak |
AHNAK nucleoprotein |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of AHNAK protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr19:8,966,640...9,054,299
Ensembl chr19:8,966,648...9,054,278
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G |
Ahr |
aryl-hydrocarbon receptor |
multiple interactions increases expression |
EXP |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein] deoxynivalenol results in increased expression of AHR mRNA; deoxynivalenol results in increased expression of AHR protein |
CTD |
PMID:35381244 |
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NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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G |
Ajuba |
ajuba LIM protein |
decreases phosphorylation |
ISO |
deoxynivalenol results in decreased phosphorylation of AJUBA protein |
CTD |
PMID:33890134 |
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NCBI chr14:54,804,926...54,815,118
Ensembl chr14:54,804,929...54,815,015
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G |
Ak7 |
adenylate kinase 7 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of AK7 mRNA |
CTD |
PMID:26763390 |
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NCBI chr12:105,670,115...105,748,706
Ensembl chr12:105,672,235...105,748,706
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G |
Akap8l |
A kinase anchor protein 8-like |
increases expression |
ISO |
deoxynivalenol results in increased expression of AKAP8L mRNA |
CTD |
PMID:31863870 |
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NCBI chr17:32,540,398...32,569,589
Ensembl chr17:32,540,398...32,569,581
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G |
Akr1b7 |
aldo-keto reductase family 1, member B7 |
multiple interactions |
EXP |
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of AKR1B7 mRNA |
CTD |
PMID:38040082 |
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NCBI chr 6:34,389,297...34,400,072
Ensembl chr 6:34,389,269...34,400,077
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G |
Akt1 |
thymoma viral proto-oncogene 1 |
multiple interactions increases phosphorylation decreases phosphorylation |
EXP ISO |
AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of AKT1 protein; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of AKT1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] [Zearalenone co-treated with deoxynivalenol] results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:15976193 PMID:16424113 PMID:24937323 PMID:34506767 PMID:35090964 PMID:37705238 More...
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NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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G |
Alb |
albumin |
decreases expression increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in decreased expression of ALB protein deoxynivalenol results in increased expression of ALB mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA deoxynivalenol results in decreased expression of ALB mRNA; deoxynivalenol results in decreased expression of ALB protein |
CTD |
PMID:25445755 PMID:28865950 PMID:28935499 |
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NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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G |
Aldh3b1 |
aldehyde dehydrogenase 3 family, member B1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ALDH3B1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr19:3,963,491...3,980,898
Ensembl chr19:3,963,491...3,979,808
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G |
Aldob |
aldolase B, fructose-bisphosphate |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of ALDOB mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
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G |
Alkbh1 |
alkB homolog 1, histone H2A dioxygenase |
increases expression |
ISO |
deoxynivalenol results in increased expression of ALKBH1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:87,474,847...87,490,609
Ensembl chr12:87,472,610...87,490,787
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G |
Alpi |
alkaline phosphatase, intestinal |
multiple interactions |
ISO |
deoxynivalenol results in decreased expression of and results in decreased activity of ALPI protein |
CTD |
PMID:20362602 |
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NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328
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G |
Alpk2 |
alpha-kinase 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ALPK2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr18:65,398,600...65,526,959
Ensembl chr18:65,398,600...65,527,137
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G |
Amigo2 |
adhesion molecule with Ig like domain 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of AMIGO2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168
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G |
Angptl7 |
angiopoietin-like 7 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ANGPTL7 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:148,579,737...148,584,919
Ensembl chr 4:148,579,640...148,584,917
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G |
Ankrd13c |
ankyrin repeat domain 13c |
increases expression |
ISO |
deoxynivalenol results in increased expression of ANKRD13C mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:157,650,886...157,713,671
Ensembl chr 3:157,652,876...157,713,671
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G |
Ankrd37 |
ankyrin repeat domain 37 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ANKRD37 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744
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G |
Anln |
anillin, actin binding protein |
increases expression |
ISO |
deoxynivalenol results in increased expression of ANLN mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:22,243,305...22,302,132
Ensembl chr 9:22,243,308...22,300,484
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G |
Anpep |
alanyl aminopeptidase, membrane |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ANPEP mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
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G |
Aoc1 |
amine oxidase, copper-containing 1 |
increases activity multiple interactions |
EXP |
deoxynivalenol results in increased activity of AOC1 protein Curcumin inhibits the reaction [deoxynivalenol results in increased activity of AOC1 protein] |
CTD |
PMID:35817260 |
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NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
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G |
Ar |
androgen receptor |
multiple interactions decreases activity |
ISO |
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein deoxynivalenol results in decreased activity of AR protein |
CTD |
PMID:27481073 |
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NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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G |
Arglu1 |
arginine and glutamate rich 1 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of ARGLU1 protein |
CTD |
PMID:23811945 |
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NCBI chr 8:8,716,307...8,741,818
Ensembl chr 8:8,715,075...8,740,521
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G |
Arhgap45 |
Rho GTPase activating protein 45 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of ARHGAP45 protein |
CTD |
PMID:23811945 |
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NCBI chr10:79,852,505...79,867,305
Ensembl chr10:79,852,487...79,867,306
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G |
Ark2n |
arkadia (RNF111) N-terminal like PKA signaling regulator 2N |
increases expression |
ISO |
deoxynivalenol results in increased expression of ARK2N mRNA |
CTD |
PMID:31863870 |
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NCBI chr18:77,719,184...77,802,190
Ensembl chr18:77,719,193...77,802,186
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G |
Armc10 |
armadillo repeat containing 10 |
affects phosphorylation increases phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of ARMC10 protein deoxynivalenol results in increased phosphorylation of ARMC10 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr 5:21,851,004...21,867,697
Ensembl chr 5:21,850,811...21,867,692
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G |
Ascc3 |
activating signal cointegrator 1 complex subunit 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of ASCC3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:50,468,756...50,727,300
Ensembl chr10:50,468,765...50,727,581
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G |
Ascl2 |
achaete-scute family bHLH transcription factor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of ASCL2 mRNA |
CTD |
PMID:19438726 |
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NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001
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G |
Ascl4 |
achaete-scute family bHLH transcription factor 4 |
increases expression |
ISO |
deoxynivalenol results in increased expression of ASCL4 mRNA |
CTD |
PMID:37419272 |
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NCBI chr10:85,763,266...85,765,513
Ensembl chr10:85,763,545...85,782,070
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G |
Asns |
asparagine synthetase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ASNS mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
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G |
Atf1 |
activating transcription factor 1 |
multiple interactions increases phosphorylation increases expression |
EXP ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein] deoxynivalenol results in increased expression of ATF1 mRNA |
CTD |
PMID:16424113 PMID:22846391 |
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NCBI chr15:100,125,729...100,159,129
Ensembl chr15:100,125,700...100,159,125
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G |
Atf2 |
activating transcription factor 2 |
increases expression multiple interactions increases phosphorylation affects localization |
ISO EXP |
deoxynivalenol results in increased expression of ATF2 mRNA 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF2 protein] deoxynivalenol affects the localization of ATF2 protein |
CTD |
PMID:12604842 PMID:15772366 PMID:22846391 |
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NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions decreases expression increases expression increases response to substance decreases degradation |
ISO EXP |
[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein] deoxynivalenol results in decreased expression of ATF3 mRNA deoxynivalenol results in increased expression of ATF3 mRNA; deoxynivalenol results in increased expression of ATF3 protein; deoxynivalenol results in increased expression of ATF3 protein alternative form ATF3 protein results in increased susceptibility to deoxynivalenol deoxynivalenol results in decreased degradation of ATF3 mRNA; deoxynivalenol results in decreased degradation of ATF3 protein |
CTD |
PMID:19101521 PMID:19360757 PMID:21074547 PMID:22003189 PMID:22846391 PMID:23253260 PMID:30286430 PMID:35314294 More...
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NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression |
EXP ISO |
ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA] deoxynivalenol results in increased expression of ATF6 protein deoxynivalenol results in increased expression of ATF6 mRNA |
CTD |
PMID:19336499 PMID:20682335 PMID:22846391 |
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NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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G |
Atg14 |
autophagy related 14 |
increases expression |
ISO |
deoxynivalenol results in increased expression of ATG14 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106
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G |
Atg4b |
autophagy related 4B, cysteine peptidase |
increases expression |
ISO |
deoxynivalenol results in increased expression of ATG4B mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:93,682,627...93,717,328
Ensembl chr 1:93,679,222...93,718,332
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G |
Atg5 |
autophagy related 5 |
multiple interactions increases expression |
EXP |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein] deoxynivalenol results in increased expression of ATG5 mRNA; deoxynivalenol results in increased expression of ATG5 protein |
CTD |
PMID:35381244 |
|
NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
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G |
Atp10a |
ATPase, class V, type 10A |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP10A mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:58,305,896...58,479,783
Ensembl chr 7:58,305,914...58,479,168
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G |
Atp5f1c |
ATP synthase F1 subunit gamma |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP5F1C protein |
CTD |
PMID:33890134 |
|
NCBI chr 2:10,060,841...10,085,321
Ensembl chr 2:10,060,827...10,085,321
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP5PD protein |
CTD |
PMID:33890134 |
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NCBI chr11:115,306,517...115,310,775
Ensembl chr11:115,306,515...115,310,788
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G |
Atp6v1a |
ATPase, H+ transporting, lysosomal V1 subunit A |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP6V1A protein |
CTD |
PMID:33890134 |
|
NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
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G |
Atp6v1b2 |
ATPase, H+ transporting, lysosomal V1 subunit B2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP6V1B2 protein |
CTD |
PMID:33890134 |
|
NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
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G |
Atp6v1d |
ATPase, H+ transporting, lysosomal V1 subunit D |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP6V1D protein |
CTD |
PMID:33890134 |
|
NCBI chr12:78,889,756...78,908,810
Ensembl chr12:78,887,499...78,908,412
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G |
Atp6v1g1 |
ATPase, H+ transporting, lysosomal V1 subunit G1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP6V1G1 protein |
CTD |
PMID:33890134 |
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NCBI chr 4:63,463,002...63,468,938
Ensembl chr 4:63,463,009...63,468,987
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G |
Atp6v1h |
ATPase, H+ transporting, lysosomal V1 subunit H |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP6V1H protein |
CTD |
PMID:33890134 |
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NCBI chr 1:5,153,201...5,233,438
Ensembl chr 1:5,140,241...5,232,752
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G |
Atp8b2 |
ATPase, class I, type 8B, member 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ATP8B2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:89,846,795...89,870,645
Ensembl chr 3:89,846,788...89,870,815
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G |
Atrx |
ATRX, chromatin remodeler |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of ATRX protein |
CTD |
PMID:23811945 |
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NCBI chr X:104,841,221...104,972,978
Ensembl chr X:104,841,221...104,973,009
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G |
B3galt4 |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of B3GALT4 mRNA |
CTD |
PMID:26763390 |
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NCBI chr17:34,168,886...34,170,462
Ensembl chr17:34,168,883...34,170,462
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G |
Bach2 |
BTB and CNC homology, basic leucine zipper transcription factor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BACH2 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
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G |
Bad |
BCL2-associated agonist of cell death |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of BAD protein |
CTD |
PMID:15976193 |
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NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
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G |
Bag3 |
BCL2-associated athanogene 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BAG3 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BAK1 mRNA |
CTD |
PMID:20702593 |
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NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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G |
Bax |
BCL2-associated X protein |
multiple interactions increases expression affects localization decreases expression |
ISO EXP |
[Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein] Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA] deoxynivalenol results in increased expression of BAX mRNA; deoxynivalenol results in increased expression of BAX protein deoxynivalenol affects the localization of BAX protein deoxynivalenol results in decreased expression of BAX mRNA |
CTD |
PMID:15976193 PMID:17166419 PMID:19410639 PMID:22269384 PMID:25445755 PMID:35090964 PMID:35817260 PMID:37705238 More...
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NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Bbc3 |
BCL2 binding component 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BBC3 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
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G |
Bcl10 |
B cell leukemia/lymphoma 10 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BCL10 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 3:145,630,017...145,640,121
Ensembl chr 3:145,628,559...145,640,111
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
multiple interactions decreases expression increases expression |
ISO EXP |
Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein] deoxynivalenol results in decreased expression of BCL2 mRNA; deoxynivalenol results in decreased expression of BCL2 protein Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in decreased expression of BCL2 mRNA]; Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein] deoxynivalenol results in increased expression of BCL2 mRNA |
CTD |
PMID:17166419 PMID:22269384 PMID:25445755 PMID:35817260 PMID:37705238 PMID:38040082 More...
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bcl2l1 |
BCL2-like 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
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G |
Bcl2l13 |
BCL2 like 13 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BCL2L13 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 6:120,813,167...120,869,803
Ensembl chr 6:120,813,173...120,869,803
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G |
Bcl6 |
B cell leukemia/lymphoma 6 |
increases expression |
EXP ISO |
deoxynivalenol results in increased expression of BCL6 mRNA |
CTD |
PMID:22968694 PMID:31863870 |
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NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
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G |
Bclaf1 |
BCL2-associated transcription factor 1 |
increases expression affects phosphorylation |
ISO EXP |
deoxynivalenol results in increased expression of BCLAF1 mRNA deoxynivalenol affects the phosphorylation of BCLAF1 protein |
CTD |
PMID:22846391 PMID:23352502 PMID:23811945 |
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NCBI chr10:20,187,897...20,218,390
Ensembl chr10:20,188,215...20,220,359
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G |
Becn1 |
beclin 1, autophagy related |
increases expression decreases expression multiple interactions |
ISO EXP |
deoxynivalenol results in increased expression of BECN1 mRNA deoxynivalenol results in decreased expression of BECN1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of BECN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA] |
CTD |
PMID:34677630 PMID:35381244 PMID:38040082 |
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NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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G |
Bend7 |
BEN domain containing 7 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BEND7 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:4,722,593...4,807,035
Ensembl chr 2:4,722,642...4,806,953
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G |
Bid |
BH3 interacting domain death agonist |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of BID mRNA |
CTD |
PMID:22269384 |
|
NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
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G |
Bin1 |
bridging integrator 1 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of BIN1 protein |
CTD |
PMID:23352502 |
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NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
multiple interactions |
EXP |
BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GOT1 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of CLOCK protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of NR1D1 protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER2 protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER3 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CLOCK mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER3 mRNA] |
CTD |
PMID:36602574 |
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NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
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G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BMP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805
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G |
Bnip1 |
BCL2/adenovirus E1B interacting protein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of BNIP1 mRNA |
CTD |
PMID:22846391 |
|
NCBI chr17:26,999,876...27,011,539
Ensembl chr17:27,000,040...27,011,539
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G |
Bnip2 |
BCL2/adenovirus E1B interacting protein 2 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of BNIP2 protein |
CTD |
PMID:23352502 |
|
NCBI chr 9:69,896,660...69,918,941
Ensembl chr 9:69,896,748...69,915,599
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G |
Bptf |
bromodomain PHD finger transcription factor |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of BPTF protein |
CTD |
PMID:23352502 |
|
NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953
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G |
Brd3 |
bromodomain containing 3 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of BRD3 protein |
CTD |
PMID:23811945 |
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NCBI chr 2:27,335,588...27,397,669
Ensembl chr 2:27,335,591...27,397,674
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G |
Bst1 |
bone marrow stromal cell antigen 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of BST1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:43,976,235...44,000,810
Ensembl chr 5:43,976,227...44,001,328
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G |
Bub1b |
BUB1B, mitotic checkpoint serine/threonine kinase |
increases expression |
ISO |
deoxynivalenol results in increased expression of BUB1B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072
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G |
Bub3 |
BUB3 mitotic checkpoint protein |
increases expression |
ISO |
deoxynivalenol results in increased expression of BUB3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:131,162,081...131,173,625
Ensembl chr 7:131,161,951...131,173,624
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G |
C3 |
complement component 3 |
increases expression |
EXP |
deoxynivalenol results in increased expression of C3 mRNA |
CTD |
PMID:22968694 |
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NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
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G |
C3ar1 |
complement component 3a receptor 1 |
increases expression |
EXP |
deoxynivalenol results in increased expression of C3AR1 mRNA |
CTD |
PMID:12604170 PMID:22968694 |
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NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120
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G |
C4b |
complement C4B (Chido blood group) |
increases expression |
EXP |
deoxynivalenol results in increased expression of C4B mRNA |
CTD |
PMID:22968694 |
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NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
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G |
Cacna1d |
calcium channel, voltage-dependent, L type, alpha 1D subunit |
increases expression |
ISO |
deoxynivalenol results in increased expression of CACNA1D mRNA |
CTD |
PMID:23792671 |
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NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412
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G |
Cacng6 |
calcium channel, voltage-dependent, gamma subunit 6 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CACNG6 mRNA |
CTD |
PMID:26763390 |
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NCBI chr 7:3,472,017...3,484,183
Ensembl chr 7:3,472,711...3,484,183
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G |
Canx |
calnexin |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of CANX protein |
CTD |
PMID:23811945 |
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NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
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G |
Card11 |
caspase recruitment domain family, member 11 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of CARD11 protein |
CTD |
PMID:23811945 |
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NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337
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G |
Casc3 |
exon junction complex subunit |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of CASC3 protein |
CTD |
PMID:23811945 |
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NCBI chr11:98,700,634...98,724,633
Ensembl chr11:98,695,731...98,724,640
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G |
Casp1 |
caspase 1 |
increases expression increases cleavage multiple interactions |
EXP |
deoxynivalenol results in increased expression of CASP1 mRNA deoxynivalenol results in increased cleavage of CASP1 protein deoxynivalenol promotes the reaction [fumonisin B1 results in increased cleavage of CASP1 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased cleavage of CASP1 protein] |
CTD |
PMID:36309173 |
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NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
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G |
Casp3 |
caspase 3 |
increases activity increases cleavage multiple interactions increases expression decreases expression |
ISO EXP |
deoxynivalenol results in increased activity of CASP3 protein deoxynivalenol results in increased cleavage of CASP3 protein benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein] deoxynivalenol results in increased expression of CASP3 mRNA; deoxynivalenol results in increased expression of CASP3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [deoxynivalenol results in increased activity of CASP3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; deoxynivalenol results in increased activity of and results in increased cleavage of CASP3 protein; deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; lauric acid inhibits the reaction [deoxynivalenol results in increased cleavage of CASP3 protein]; pifithrin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA] deoxynivalenol results in decreased expression of CASP3 protein [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; [Zearalenone co-treated with deoxynivalenol] results in increased expression of CASP3 protein; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein |
CTD |
PMID:15772366 PMID:15976193 PMID:17166419 PMID:19410639 PMID:19664677 PMID:22269384 PMID:22491426 PMID:25445755 PMID:27757495 PMID:30668976 PMID:34506767 PMID:34673182 PMID:34677630 PMID:35090964 PMID:35314294 PMID:35817260 PMID:35925383 PMID:37705238 More...
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp7 |
caspase 7 |
increases activity |
ISO |
deoxynivalenol results in increased activity of CASP7 protein |
CTD |
PMID:27757495 |
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NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
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G |
Casp8 |
caspase 8 |
increases expression multiple interactions |
ISO EXP |
deoxynivalenol results in increased expression of CASP8 mRNA benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP8 mRNA] [Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA] deoxynivalenol results in increased activity of and results in increased cleavage of CASP8 protein |
CTD |
PMID:22491426 PMID:22846391 PMID:30668976 PMID:34673182 |
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NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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G |
Casp9 |
caspase 9 |
decreases expression increases expression multiple interactions increases activity |
ISO EXP |
deoxynivalenol results in decreased expression of CASP9 protein deoxynivalenol results in increased expression of CASP9 mRNA benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP9 mRNA] Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA] deoxynivalenol results in increased activity of and results in increased cleavage of CASP9 protein deoxynivalenol results in increased expression of CASP9 mRNA; deoxynivalenol results in increased expression of CASP9 protein deoxynivalenol results in increased activity of CASP9 protein |
CTD |
PMID:22269384 PMID:22491426 PMID:30668976 PMID:34673182 PMID:35314294 |
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NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
Casr |
calcium-sensing receptor |
multiple interactions |
EXP |
CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein] |
CTD |
PMID:25787141 |
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NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
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G |
Cat |
catalase |
increases expression decreases activity decreases expression multiple interactions increases activity |
ISO EXP |
deoxynivalenol results in increased expression of CAT mRNA; deoxynivalenol results in increased expression of CAT protein deoxynivalenol results in decreased activity of CAT protein deoxynivalenol results in decreased expression of CAT mRNA Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CAT mRNA] deoxynivalenol results in increased activity of CAT protein Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein] |
CTD |
PMID:20347963 PMID:34400200 PMID:34673182 PMID:35314294 PMID:35817260 PMID:37705238 More...
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Cbll1 |
Casitas B-lineage lymphoma-like 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CBLL1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:31,534,828...31,550,536
Ensembl chr12:31,534,828...31,549,615
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G |
Cbs |
cystathionine beta-synthase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CBS mRNA |
CTD |
PMID:31863870 |
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NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212
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G |
Cbx5 |
chromobox 5 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of CBX5 protein |
CTD |
PMID:23811945 |
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NCBI chr15:103,099,973...103,148,337
Ensembl chr15:103,099,971...103,148,243
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G |
Ccdc112 |
coiled-coil domain containing 112 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CCDC112 mRNA |
CTD |
PMID:31863870 |
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NCBI chr18:46,415,218...46,445,016
Ensembl chr18:46,415,218...46,444,995
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G |
Cck |
cholecystokinin |
increases secretion multiple interactions increases expression |
EXP |
deoxynivalenol results in increased secretion of CCK protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; [N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine co-treated with Ruthenium Red] inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; TRPA1 affects the reaction [deoxynivalenol results in increased secretion of CCK protein] |
CTD |
PMID:22903826 PMID:24385417 PMID:25787141 PMID:26979077 |
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NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCL1 mRNA |
CTD |
PMID:22968694 |
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NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCL11 mRNA |
CTD |
PMID:22968694 |
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NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCL12 mRNA |
CTD |
PMID:22968694 |
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NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCL17 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of CCL2 mRNA; deoxynivalenol results in increased expression of CCL2 protein Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL2 mRNA] |
CTD |
PMID:15371230 PMID:15681167 PMID:17090620 PMID:22846391 PMID:22968694 PMID:24793808 More...
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NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CCL20 mRNA |
CTD |
PMID:27757495 PMID:35314294 |
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NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCL22 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
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G |
Ccl24 |
C-C motif chemokine ligand 24 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCL24 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
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G |
Ccl25 |
C-C motif chemokine ligand 25 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of CCL25 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 8:4,375,207...4,410,020
Ensembl chr 8:4,375,210...4,410,020
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression |
ISO EXP |
deoxynivalenol results in increased expression of CCL3 mRNA |
CTD |
PMID:22846391 PMID:22968694 |
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NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
EXP ISO |
deoxynivalenol results in increased expression of CCL4 mRNA |
CTD |
PMID:21074547 PMID:22846391 PMID:22968694 PMID:27757495 |
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NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of CCL5 mRNA benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CCL5 mRNA] |
CTD |
PMID:22968694 PMID:27757495 PMID:35925383 |
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NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions increases expression |
EXP |
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL7 mRNA] |
CTD |
PMID:15371230 PMID:15681167 PMID:22968694 PMID:24793808 |
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NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
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G |
Ccn1 |
cellular communication network factor 1 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCN1 mRNA |
CTD |
PMID:15371230 |
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NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CCN2 mRNA |
CTD |
PMID:35588983 |
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NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
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G |
Ccnb1 |
cyclin B1 |
multiple interactions increases expression |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CCNB1 mRNA] |
CTD |
PMID:34677630 |
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NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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G |
Ccnd1 |
cyclin D1 |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of CCND1 mRNA; deoxynivalenol results in increased expression of CCND1 protein Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of CCND1 protein] |
CTD |
PMID:22454431 PMID:24937323 PMID:32416088 |
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccne1 |
cyclin E1 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of CCNE1 mRNA |
CTD |
PMID:27456127 |
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NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
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G |
Ccng2 |
cyclin G2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CCNG2 mRNA |
CTD |
PMID:30169763 |
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NCBI chr 5:93,415,432...93,424,090
Ensembl chr 5:93,415,116...93,424,090
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G |
Ccny |
cyclin Y |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of CCNY protein |
CTD |
PMID:23811945 |
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NCBI chr18:9,312,304...9,450,188
Ensembl chr18:9,312,304...9,450,154
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G |
Ccr1 |
C-C motif chemokine receptor 1 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCR1 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCR2 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
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G |
Ccr3 |
C-C motif chemokine receptor 3 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCR3 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726
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G |
Ccr4 |
C-C motif chemokine receptor 4 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CCR4 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CCR7 mRNA |
CTD |
PMID:22968694 |
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NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
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G |
Cd14 |
CD14 antigen |
multiple interactions |
ISO |
deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein] |
CTD |
PMID:19549553 |
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NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
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G |
Cd248 |
CD248 antigen, endosialin |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CD248 mRNA |
CTD |
PMID:31863870 |
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NCBI chr19:5,118,106...5,120,668
Ensembl chr19:5,118,106...5,120,710
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G |
Cd40 |
CD40 antigen |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of CD40 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
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G |
Cd55 |
CD55 molecule, decay accelerating factor for complement |
increases expression |
ISO |
deoxynivalenol results in increased expression of CD55 mRNA |
CTD |
PMID:22846391 PMID:24247028 |
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NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481
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G |
Cd68 |
CD68 antigen |
increases expression |
EXP |
deoxynivalenol results in increased expression of CD68 mRNA |
CTD |
PMID:25549547 |
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NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979
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G |
Cd69 |
CD69 antigen |
increases expression |
ISO |
deoxynivalenol results in increased expression of CD69 mRNA |
CTD |
PMID:22846391 PMID:24247028 |
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NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
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G |
Cd80 |
CD80 antigen |
increases expression |
EXP |
deoxynivalenol results in increased expression of CD80 mRNA |
CTD |
PMID:21074547 |
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NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
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G |
Cd86 |
CD86 antigen |
increases expression |
EXP |
deoxynivalenol results in increased expression of CD86 mRNA |
CTD |
PMID:21074547 |
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NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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G |
Cdan1 |
codanin 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CDAN1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:120,546,635...120,561,998
Ensembl chr 2:120,546,635...120,680,609
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G |
Cdh13 |
cadherin 13 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CDH13 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:119,010,150...120,051,668
Ensembl chr 8:119,010,472...120,051,660
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G |
Cdk1 |
cyclin dependent kinase 1 |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of CDK1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDK1 mRNA] |
CTD |
PMID:31863870 PMID:34677630 |
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NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
increases expression multiple interactions decreases degradation |
ISO EXP |
deoxynivalenol results in increased expression of CDKN1A mRNA; deoxynivalenol results in increased expression of CDKN1A protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDKN1A mRNA]; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [deoxynivalenol results in decreased degradation of CDKN1A mRNA] |
CTD |
PMID:18006205 PMID:22454431 PMID:30169763 PMID:30286430 PMID:31863870 PMID:34677630 More...
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NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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G |
Cdkn3 |
cyclin dependent kinase inhibitor 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CDKN3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:46,997,912...47,008,987
Ensembl chr14:46,997,998...47,009,126
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions decreases expression |
ISO |
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA deoxynivalenol results in decreased expression of CEBPA mRNA |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions increases activity affects localization |
EXP |
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CEBPB protein] deoxynivalenol affects the localization of CEBPB protein |
CTD |
PMID:12604842 PMID:15772366 |
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NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
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G |
Cenpw |
centromere protein W |
increases expression |
ISO |
deoxynivalenol results in increased expression of CENPW mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:30,072,005...30,076,599
Ensembl chr10:30,070,565...30,076,556
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G |
Cercam |
cerebral endothelial cell adhesion molecule |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CERCAM mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:29,735,442...29,772,857
Ensembl chr 2:29,759,176...29,772,852
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G |
Cgref1 |
cell growth regulator with EF hand domain 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CGREF1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:31,090,487...31,102,771
Ensembl chr 5:31,090,487...31,102,935
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G |
Chac1 |
ChaC, cation transport regulator 1 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of CHAC1 mRNA |
CTD |
PMID:23253260 |
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NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862
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G |
Champ1 |
chromosome alignment maintaining phosphoprotein 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of CHAMP1 protein |
CTD |
PMID:23352502 |
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NCBI chr 8:13,919,699...13,931,637
Ensembl chr 8:13,919,641...13,931,639
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G |
Chka |
choline kinase alpha |
increases expression |
ISO |
deoxynivalenol results in increased expression of CHKA mRNA |
CTD |
PMID:31863870 |
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NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369
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G |
Chn1 |
chimerin 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CHN1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:73,441,004...73,605,723
Ensembl chr 2:73,441,004...73,605,690
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G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CHORDC1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:18,203,563...18,225,296
Ensembl chr 9:18,203,421...18,228,738
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G |
Chuk |
conserved helix-loop-helix ubiquitous kinase |
increases phosphorylation increases expression |
ISO EXP |
deoxynivalenol results in increased phosphorylation of CHUK protein deoxynivalenol results in increased expression of CHUK mRNA |
CTD |
PMID:20633634 PMID:34400200 |
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NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
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G |
Cish |
cytokine inducible SH2-containing protein |
increases expression |
EXP |
deoxynivalenol results in increased expression of CISH mRNA |
CTD |
PMID:19625342 |
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NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
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G |
Ckap2 |
cytoskeleton associated protein 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CKAP2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:22,658,168...22,675,835
Ensembl chr 8:22,658,176...22,675,835
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G |
Ckap5 |
cytoskeleton associated protein 5 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CKAP5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:91,357,092...91,451,024
Ensembl chr 2:91,357,107...91,451,009
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G |
Cks1b |
CDC28 protein kinase 1b |
increases expression |
ISO |
deoxynivalenol results in increased expression of CKS1B mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:89,322,779...89,325,598
Ensembl chr 3:89,322,779...89,325,690
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G |
Cldn1 |
claudin 1 |
increases expression multiple interactions decreases expression affects expression |
ISO EXP |
deoxynivalenol results in increased expression of CLDN1 mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] deoxynivalenol results in decreased expression of CLDN1 mRNA; deoxynivalenol results in decreased expression of CLDN1 protein [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein; deoxynivalenol results in decreased expression of and affects the localization of CLDN1 protein deoxynivalenol affects the expression of CLDN1 protein |
CTD |
PMID:24568843 PMID:28865950 PMID:28935499 PMID:34506767 PMID:35381244 PMID:35817260 More...
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NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
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G |
Cldn2 |
claudin 2 |
affects expression increases expression |
EXP |
deoxynivalenol affects the expression of CLDN2 protein deoxynivalenol results in increased expression of CLDN2 mRNA |
CTD |
PMID:24568843 |
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NCBI chr X:138,701,552...138,712,135
Ensembl chr X:138,701,577...138,712,135
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G |
Cldn3 |
claudin 3 |
multiple interactions increases expression affects expression |
ISO EXP |
deoxynivalenol results in decreased expression of and affects the localization of CLDN3 protein [deoxynivalenol results in increased susceptibility to Antigens] which results in decreased expression of CLDN3 mRNA deoxynivalenol results in increased expression of CLDN3 mRNA deoxynivalenol affects the expression of CLDN3 protein |
CTD |
PMID:24568843 PMID:28935500 |
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NCBI chr 5:135,015,068...135,016,330
Ensembl chr 5:135,015,068...135,016,326
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G |
Cldn4 |
claudin 4 |
decreases expression increases expression multiple interactions |
ISO EXP |
deoxynivalenol results in decreased expression of CLDN4 protein deoxynivalenol results in increased expression of CLDN4 mRNA deoxynivalenol results in decreased expression of and affects the localization of CLDN4 protein |
CTD |
PMID:19289138 PMID:20362602 PMID:24568843 |
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NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
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G |
Clic3 |
chloride intracellular channel 3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CLIC3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:25,346,855...25,348,789
Ensembl chr 2:25,346,850...25,348,788
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G |
Clock |
clock circadian regulator |
decreases expression multiple interactions |
EXP |
deoxynivalenol results in decreased expression of CLOCK protein BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of CLOCK protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CLOCK mRNA] |
CTD |
PMID:36602574 |
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NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639
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G |
Cnpy2 |
canopy FGF signaling regulator 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CNPY2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:128,157,972...128,163,056
Ensembl chr10:128,158,328...128,163,422
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G |
Col15a1 |
collagen, type XV, alpha 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of COL15A1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:47,207,744...47,313,165
Ensembl chr 4:47,208,161...47,313,167
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G |
Col4a1 |
collagen, type IV, alpha 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of COL4A1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
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G |
Col5a1 |
collagen, type V, alpha 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of COL5A1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526
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G |
Col6a2 |
collagen, type VI, alpha 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of COL6A2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:76,431,590...76,459,464
Ensembl chr10:76,431,596...76,459,464
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G |
Comt |
catechol-O-methyltransferase |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of COMT protein |
CTD |
PMID:23811945 |
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NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
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G |
Coro1a |
coronin, actin binding protein 1A |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of CORO1A protein |
CTD |
PMID:23811945 |
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NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959
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G |
Coro2b |
coronin, actin binding protein, 2B |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CORO2B mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:62,326,770...62,444,326
Ensembl chr 9:62,326,774...62,444,326
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G |
Cox5b |
cytochrome c oxidase subunit 5B |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of COX5B protein |
CTD |
PMID:33890134 |
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NCBI chr 1:36,730,568...36,732,469
Ensembl chr 1:36,730,530...36,732,762
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G |
Cpsf2 |
cleavage and polyadenylation specific factor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CPSF2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:101,940,345...101,972,252
Ensembl chr12:101,942,247...101,972,683
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases phosphorylation increases activity affects localization |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased activity of CREB1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein] deoxynivalenol affects the localization of CREB1 protein |
CTD |
PMID:12604842 PMID:16424113 PMID:32416088 |
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NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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G |
Creb5 |
cAMP responsive element binding protein 5 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CREB5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:53,264,154...53,677,349
Ensembl chr 6:53,264,255...53,677,361
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G |
Crebbp |
CREB binding protein |
increases expression |
ISO |
deoxynivalenol results in increased expression of CREBBP mRNA |
CTD |
PMID:24247028 |
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NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
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G |
Creld1 |
cysteine-rich with EGF-like domains 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CRELD1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:113,460,317...113,470,304
Ensembl chr 6:113,460,258...113,470,304
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G |
Crp |
C-reactive protein, pentraxin-related |
increases expression |
EXP |
deoxynivalenol results in increased expression of CRP mRNA |
CTD |
PMID:22968694 |
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NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
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G |
Cry1 |
cryptochrome circadian regulator 1 |
multiple interactions |
EXP |
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 protein] |
CTD |
PMID:36602574 |
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NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
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G |
Cry2 |
cryptochrome circadian regulator 2 |
multiple interactions |
EXP |
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 protein] |
CTD |
PMID:36602574 |
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NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388
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G |
Csf3 |
colony stimulating factor 3 (granulocyte) |
increases expression |
ISO |
deoxynivalenol results in increased expression of CSF3 mRNA |
CTD |
PMID:27757495 |
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NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
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G |
Cthrc1 |
collagen triple helix repeat containing 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CTHRC1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:38,940,327...38,950,516
Ensembl chr15:38,940,327...38,950,516
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G |
Ctnna1 |
catenin alpha 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CTNNA1 protein |
CTD |
PMID:33890134 |
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NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
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G |
Ctnnb1 |
catenin beta 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of CTNNB1 protein |
CTD |
PMID:23811945 |
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NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
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G |
Ctso |
cathepsin O |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CTSO mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:81,839,908...81,864,032
Ensembl chr 3:81,839,908...81,864,032
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G |
Cwf19l2 |
CWF19 like cell cycle control factor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CWF19L2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:3,403,592...3,479,236
Ensembl chr 9:3,403,592...3,479,236
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CX3CL1 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA] |
CTD |
PMID:22003189 PMID:27757495 |
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NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
decreases expression increases expression |
EXP |
deoxynivalenol results in decreased expression of CXCL10 mRNA deoxynivalenol results in increased expression of CXCL10 mRNA; deoxynivalenol results in increased expression of CXCL10 protein |
CTD |
PMID:15371230 PMID:22968694 PMID:34400200 |
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NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
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G |
Cxcl11 |
chemokine (C-X-C motif) ligand 11 |
decreases expression increases expression |
EXP ISO |
deoxynivalenol results in decreased expression of CXCL11 mRNA deoxynivalenol results in increased expression of CXCL11 mRNA |
CTD |
PMID:22968694 PMID:27757495 |
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NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344
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G |
Cxcl15 |
C-X-C motif chemokine ligand 15 |
decreases degradation multiple interactions increases secretion increases expression |
ISO |
deoxynivalenol results in decreased degradation of CXCL8 mRNA 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased secretion of CXCL8 protein]; 2-Aminopurine inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; 2-Aminopurine inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; 2-chloro-5-nitrobenzanilide promotes the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; [deoxynivalenol results in increased expression of ELAVL1 protein] which results in decreased degradation of CXCL8 mRNA; [deoxynivalenol results in increased phosphorylation of MAPK1 protein] which results in increased expression of CXCL8 protein; [deoxynivalenol results in increased phosphorylation of MAPK3 protein] which results in increased expression of CXCL8 protein; Adenine inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; cereulide inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; cereulide inhibits the reaction [deoxynivalenol results in increased secretion of CXCL8 protein]; Cycloheximide inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; Dactinomycin inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; deoxynivalenol inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; deoxynivalenol inhibits the reaction [NFKB2 protein binds to CXCL8 promoter]; deoxynivalenol promotes the reaction [RELA protein binds to CXCL8 promoter]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; GW 506033X inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; GW 506033X inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; lipopolysaccharide, E coli O55-B5 inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; lipopolysaccharide, E coli O55-B5 inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; PPARG protein affects the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; prolinedithiocarbamate inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; RELA protein promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased secretion of CXCL8 protein]; triptolide inhibits the reaction [deoxynivalenol results in increased secretion of CXCL8 protein] deoxynivalenol results in increased secretion of CXCL8 mRNA; deoxynivalenol results in increased secretion of CXCL8 protein [deoxynivalenol results in increased expression of EGR1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased expression of CXCL8 mRNA; deoxynivalenol results in increased expression of CXCL8 protein |
CTD |
PMID:16364386 PMID:17166736 PMID:17636245 PMID:17707346 PMID:18308354 PMID:18485432 PMID:18599499 PMID:19591856 PMID:20181660 PMID:20633634 PMID:22003189 PMID:23792671 PMID:27757495 PMID:32065293 PMID:33170220 PMID:35314294 PMID:37315771 More...
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NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of CXCL2 mRNA; deoxynivalenol results in increased expression of CXCL2 protein deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CXCL2 mRNA] |
CTD |
PMID:12604170 PMID:15371230 PMID:15681167 PMID:22968694 PMID:24793808 PMID:27757495 More...
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NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO EXP |
[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA] deoxynivalenol results in increased expression of CXCL1 mRNA; deoxynivalenol results in increased expression of CXCL3 mRNA |
CTD |
PMID:15371230 PMID:15681167 PMID:22003189 PMID:22968694 PMID:27757495 |
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NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CXCL9 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CXCR1 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
increases expression |
EXP |
deoxynivalenol results in increased expression of CXCR2 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CXCR4 mRNA |
CTD |
PMID:22846391 PMID:27757495 |
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NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
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G |
Cyc1 |
cytochrome c-1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CYC1 protein |
CTD |
PMID:33890134 |
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NCBI chr15:76,227,711...76,230,460
Ensembl chr15:76,227,723...76,230,460
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G |
Cycs |
cytochrome c, somatic |
affects localization increases expression decreases expression increases activity |
EXP ISO |
deoxynivalenol affects the localization of CYCS protein deoxynivalenol results in increased expression of CYCS mRNA; deoxynivalenol results in increased expression of CYCS protein deoxynivalenol results in decreased expression of CYCS protein deoxynivalenol results in increased activity of CYCS protein |
CTD |
PMID:15976193 PMID:22269384 PMID:22846391 |
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NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
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G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CYP11B2 mRNA |
CTD |
PMID:22982764 |
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NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,467...74,728,167
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CYP17A1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO EXP |
deoxynivalenol results in increased expression of CYP1A1 mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:22982764 PMID:35381244 |
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NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:20702593 |
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NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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G |
Cyp21a1 |
cytochrome P450, family 21, subfamily a, polypeptide 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of CYP21A2 mRNA |
CTD |
PMID:22982764 |
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NCBI chr17:35,020,322...35,023,400
Ensembl chr17:35,020,322...35,023,535
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
multiple interactions |
ISO |
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA |
CTD |
PMID:28865950 PMID:28935499 |
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NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
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G |
Cytl1 |
cytokine-like 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of CYTL1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:37,892,863...37,897,164
Ensembl chr 5:37,892,863...37,897,164
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G |
Ddb2 |
damage specific DNA binding protein 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of DDB2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:91,041,924...91,067,465
Ensembl chr 2:91,041,917...91,067,327
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression decreases expression |
ISO EXP |
deoxynivalenol results in increased expression of DDIT3 mRNA deoxynivalenol results in decreased expression of DDIT3 mRNA |
CTD |
PMID:22846391 PMID:23253260 PMID:30169763 |
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NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of DDIT4 mRNA |
CTD |
PMID:31863870 |
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NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
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G |
Ddx21 |
DExD box helicase 21 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of DDX21 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr10:62,416,026...62,438,077
Ensembl chr10:62,416,030...62,438,060
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G |
Ddx39a |
DEAD box helicase 39a |
increases expression |
ISO |
deoxynivalenol results in increased expression of DDX39A mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:84,441,806...84,453,533
Ensembl chr 8:84,441,806...84,453,521
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G |
Ddx52 |
DExD box helicase 52 |
increases expression |
ISO |
deoxynivalenol results in increased expression of DDX52 mRNA |
CTD |
PMID:31863870 |
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NCBI chr11:83,831,659...83,853,914
Ensembl chr11:83,832,888...83,853,914
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G |
Deptor |
DEP domain containing MTOR-interacting protein |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of DEPTOR mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:54,975,824...55,122,667
Ensembl chr15:54,975,713...55,122,667
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G |
Dffa |
DNA fragmentation factor, alpha subunit |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of DFFA protein |
CTD |
PMID:23811945 |
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NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104
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G |
Dgkg |
diacylglycerol kinase, gamma |
multiple interactions |
EXP |
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of DGKG mRNA |
CTD |
PMID:38040082 |
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NCBI chr16:22,285,318...22,476,051
Ensembl chr16:22,287,211...22,475,971
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G |
Dgki |
diacylglycerol kinase, iota |
multiple interactions |
EXP |
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of DGKI mRNA |
CTD |
PMID:38040082 |
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NCBI chr 6:36,814,316...37,281,034
Ensembl chr 6:36,822,957...37,277,119
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G |
Dkc1 |
dyskeratosis congenita 1, dyskerin |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of DKC1 protein |
CTD |
PMID:23811945 |
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NCBI chr X:74,139,460...74,153,382
Ensembl chr X:74,139,460...74,153,383
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G |
Dnah10 |
dynein, axonemal, heavy chain 10 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of DNAH10 protein |
CTD |
PMID:23811945 |
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NCBI chr 5:124,802,149...124,911,372
Ensembl chr 5:124,802,149...124,911,372
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
increases expression decreases expression |
EXP ISO |
deoxynivalenol results in increased expression of DNAJA1 mRNA deoxynivalenol results in decreased expression of DNAJA1 protein |
CTD |
PMID:15371230 PMID:33890134 |
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NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
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G |
Dnajc1 |
DnaJ heat shock protein family (Hsp40) member C1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of DNAJC1 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 2:18,210,445...18,402,025
Ensembl chr 2:18,200,465...18,397,641
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions decreases expression |
EXP |
deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] deoxynivalenol results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:10652249 |
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NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
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G |
Dnajc5 |
DnaJ heat shock protein family (Hsp40) member C5 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of DNAJC5 protein |
CTD |
PMID:23352502 |
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NCBI chr 2:181,162,141...181,194,679
Ensembl chr 2:181,162,278...181,196,926
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G |
Dnmt1 |
DNA methyltransferase 1 |
affects phosphorylation increases expression |
EXP ISO |
deoxynivalenol affects the phosphorylation of DNMT1 protein deoxynivalenol results in increased expression of DNMT1 mRNA; deoxynivalenol results in increased expression of DNMT1 protein |
CTD |
PMID:23352502 PMID:23811945 PMID:32738333 |
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NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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G |
Dnmt3a |
DNA methyltransferase 3A |
increases expression |
ISO |
deoxynivalenol results in increased expression of DNMT3A mRNA; deoxynivalenol results in increased expression of DNMT3A protein |
CTD |
PMID:32738333 |
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NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
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G |
Dnttip2 |
deoxynucleotidyltransferase, terminal, interacting protein 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of DNTTIP2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:122,068,045...122,078,920
Ensembl chr 3:122,068,037...122,078,920
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G |
Dsc1 |
desmocollin 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of DSC1 protein |
CTD |
PMID:33890134 |
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NCBI chr18:20,216,528...20,247,830
Ensembl chr18:20,217,241...20,247,928
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression multiple interactions |
ISO EXP |
deoxynivalenol results in increased expression of DUSP1 mRNA; deoxynivalenol results in increased expression of DUSP1 protein Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of DUSP1 mRNA] [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein |
CTD |
PMID:15371230 PMID:15681167 PMID:20708668 |
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NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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G |
Dusp6 |
dual specificity phosphatase 6 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of DUSP6 mRNA |
CTD |
PMID:24247028 |
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NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
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G |
Dusp8 |
dual specificity phosphatase 8 |
increases expression |
ISO |
deoxynivalenol results in increased expression of DUSP8 mRNA |
CTD |
PMID:23792671 |
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NCBI chr 7:141,633,224...141,649,799
Ensembl chr 7:141,633,227...141,649,580
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G |
Dync1li1 |
dynein cytoplasmic 1 light intermediate chain 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of DYNC1LI1 protein |
CTD |
PMID:23352502 |
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NCBI chr 9:114,517,899...114,552,856
Ensembl chr 9:114,517,858...114,553,370
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G |
Ecm1 |
extracellular matrix protein 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ECM1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:95,641,459...95,646,880
Ensembl chr 3:95,641,459...95,646,881
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G |
Ect2 |
ect2 oncogene |
increases expression |
ISO |
deoxynivalenol results in increased expression of ECT2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:27,151,371...27,207,971
Ensembl chr 3:27,151,371...27,208,027
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G |
Eef1b2 |
eukaryotic translation elongation factor 1 beta 2 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of EEF1B2 protein |
CTD |
PMID:23352502 |
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NCBI chr 1:63,215,990...63,219,645
Ensembl chr 1:63,215,984...63,219,645
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G |
Eef1d |
eukaryotic translation elongation factor 1 delta |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of EEF1D protein |
CTD |
PMID:23811945 |
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NCBI chr15:75,766,643...75,781,425
Ensembl chr15:75,766,054...75,781,405
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G |
Egf |
epidermal growth factor |
increases expression |
ISO |
deoxynivalenol results in increased expression of EGF mRNA |
CTD |
PMID:27757495 |
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NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
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G |
Egfr |
epidermal growth factor receptor |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of EGFR protein |
CTD |
PMID:33890134 |
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NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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G |
Egr1 |
early growth response 1 |
increases expression multiple interactions |
ISO |
[deoxynivalenol results in increased expression of EGR1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased expression of EGR1 mRNA; deoxynivalenol results in increased expression of EGR1 protein ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; deoxynivalenol results in increased expression of and results in increased phosphorylation of EGR1 protein; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA] |
CTD |
PMID:17707346 PMID:18485432 PMID:19360757 PMID:30286430 PMID:33890134 |
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NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
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G |
Eid2 |
EP300 interacting inhibitor of differentiation 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of EID2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:27,967,306...27,968,593
Ensembl chr 7:27,967,306...27,968,697
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G |
Eif2a |
eukaryotic translation initiation factor 2A |
increases phosphorylation |
ISO |
deoxynivalenol results in increased phosphorylation of EIF2A protein |
CTD |
PMID:20682335 |
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NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
decreases expression affects response to substance multiple interactions |
EXP ISO |
deoxynivalenol results in decreased expression of EIF2AK2 mRNA EIF2AK2 protein affects the susceptibility to deoxynivalenol EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA] |
CTD |
PMID:17090620 PMID:18599499 PMID:22491426 |
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NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002
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G |
Eif2b4 |
eukaryotic translation initiation factor 2B, subunit 4 delta |
increases expression |
ISO |
deoxynivalenol results in increased expression of EIF2B4 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:31,344,902...31,350,483
Ensembl chr 5:31,344,902...31,350,774
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G |
Eif2s2 |
eukaryotic translation initiation factor 2 subunit 2 beta |
affects expression |
ISO |
deoxynivalenol affects the expression of EIF2S2 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 2:154,713,330...154,734,826
Ensembl chr 2:154,713,330...154,734,855
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G |
Eif3b |
eukaryotic translation initiation factor 3, subunit B |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of EIF3B protein |
CTD |
PMID:23811945 |
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NCBI chr 5:140,405,060...140,429,113
Ensembl chr 5:140,405,083...140,429,115
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G |
Eif3c |
eukaryotic translation initiation factor 3, subunit C |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of EIF3C protein |
CTD |
PMID:23811945 |
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NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:23352502 |
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NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
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G |
Eif4g1 |
eukaryotic translation initiation factor 4, gamma 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of EIF4G1 protein |
CTD |
PMID:23352502 |
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NCBI chr16:20,491,457...20,511,633
Ensembl chr16:20,487,063...20,511,634
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G |
Eif5b |
eukaryotic translation initiation factor 5B |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of EIF5B protein |
CTD |
PMID:23811945 |
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NCBI chr 1:38,037,091...38,094,660
Ensembl chr 1:38,037,091...38,094,660
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G |
Elavl1 |
ELAV like RNA binding protein 1 |
multiple interactions |
ISO |
[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [deoxynivalenol results in increased expression of ELAVL1 protein] which results in decreased degradation of CXCL8 mRNA; deoxynivalenol results in increased expression of and results in increased localization of ELAVL1 protein; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 protein] |
CTD |
PMID:19591856 PMID:22003189 |
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NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413
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G |
Elk1 |
ELK1, member of ETS oncogene family |
increases expression |
ISO |
deoxynivalenol results in increased expression of ELK1 protein |
CTD |
PMID:33890134 |
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NCBI chr X:20,799,634...20,816,847
Ensembl chr X:20,799,634...20,816,847
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G |
Emc10 |
ER membrane protein complex subunit 10 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of EMC10 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:44,139,361...44,145,953
Ensembl chr 7:44,139,361...44,145,953
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G |
Emilin1 |
elastin microfibril interfacer 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of EMILIN1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 5:31,070,729...31,078,623
Ensembl chr 5:31,070,746...31,078,621
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G |
Eng |
endoglin |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ENG mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681
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G |
Engase |
endo-beta-N-acetylglucosaminidase |
increases expression |
ISO |
deoxynivalenol results in increased expression of ENGASE mRNA |
CTD |
PMID:23792671 |
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NCBI chr11:118,367,635...118,380,038
Ensembl chr11:118,367,655...118,380,035
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G |
Ep300 |
E1A binding protein p300 |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of EP300 protein EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form] |
CTD |
PMID:30286430 |
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NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
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G |
Ep400 |
E1A binding protein p400 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of EP400 protein |
CTD |
PMID:23352502 |
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NCBI chr 5:110,812,239...110,918,583
Ensembl chr 5:110,812,239...110,918,583
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G |
Epb41l2 |
erythrocyte membrane protein band 4.1 like 2 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of EPB41L2 protein |
CTD |
PMID:23811945 |
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NCBI chr10:25,235,680...25,399,413
Ensembl chr10:25,235,696...25,399,417
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G |
Ephx1 |
epoxide hydrolase 1, microsomal |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of EPHX1 mRNA |
CTD |
PMID:15371230 |
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NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
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G |
Ern1 |
endoplasmic reticulum to nucleus signalling 1 |
decreases expression increases expression |
ISO EXP |
deoxynivalenol results in decreased expression of ERN1 mRNA deoxynivalenol results in increased expression of ERN1 protein |
CTD |
PMID:19336499 PMID:20682335 |
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NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
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G |
Esr1 |
estrogen receptor 1 (alpha) |
increases phosphorylation multiple interactions |
ISO |
deoxynivalenol results in increased phosphorylation of ESR1 protein ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of TFF1 mRNA] |
CTD |
PMID:35588983 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Etnk1 |
ethanolamine kinase 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of ETNK1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 6:143,112,592...143,154,272
Ensembl chr 6:143,112,947...143,178,033
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G |
Evi2a |
ecotropic viral integration site 2a |
increases expression |
ISO |
deoxynivalenol results in increased expression of EVI2A mRNA |
CTD |
PMID:24247028 |
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NCBI chr11:79,417,386...79,421,435
Ensembl chr11:79,417,386...79,421,435
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G |
Evl |
Ena-vasodilator stimulated phosphoprotein |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of EVL protein |
CTD |
PMID:23811945 |
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NCBI chr12:108,520,942...108,654,775
Ensembl chr12:108,520,979...108,654,775
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G |
Exosc2 |
exosome component 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of EXOSC2 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 2:31,560,727...31,571,593
Ensembl chr 2:31,560,727...31,571,361
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G |
F3 |
coagulation factor III |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of F3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
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G |
Fabp3 |
fatty acid binding protein 3, muscle and heart |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FABP3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256
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G |
Fabp4 |
fatty acid binding protein 4, adipocyte |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FABP4 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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G |
Fabp6 |
fatty acid binding protein 6 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FABP6 mRNA |
CTD |
PMID:35224661 |
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NCBI chr11:43,486,867...43,492,389
Ensembl chr11:43,486,876...43,492,367
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G |
Fam83d |
family with sequence similarity 83, member D |
increases expression |
ISO |
deoxynivalenol results in increased expression of FAM83D mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:158,610,011...158,628,557
Ensembl chr 2:158,610,013...158,628,557
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO |
Bentonite inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of FAS protein] deoxynivalenol results in increased expression of FAS mRNA |
CTD |
PMID:26115597 |
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NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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G |
Fasl |
Fas ligand |
increases expression |
EXP |
deoxynivalenol results in increased expression of FASL mRNA |
CTD |
PMID:22968694 |
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NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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G |
Fastkd2 |
FAST kinase domains 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of FASTKD2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:63,769,758...63,792,544
Ensembl chr 1:63,769,773...63,793,814
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G |
Fbxo22 |
F-box protein 22 |
increases expression |
ISO |
deoxynivalenol results in increased expression of FBXO22 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:55,116,219...55,131,717
Ensembl chr 9:55,116,209...55,131,717
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G |
Fbxo28 |
F-box protein 28 |
increases expression |
ISO |
deoxynivalenol results in increased expression of FBXO28 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:182,140,667...182,169,171
Ensembl chr 1:182,140,667...182,169,194
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FDFT1 protein |
CTD |
PMID:33890134 |
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NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
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G |
Fdps |
farnesyl diphosphate synthetase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FDPS protein |
CTD |
PMID:33890134 |
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NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
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G |
Flna |
filamin, alpha |
decreases phosphorylation increases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of FLNA protein deoxynivalenol results in increased phosphorylation of FLNA protein |
CTD |
PMID:23811945 |
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NCBI chr X:73,267,067...73,293,787
Ensembl chr X:73,267,067...73,293,426
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G |
Fmnl1 |
formin-like 1 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of FMNL1 protein |
CTD |
PMID:23352502 |
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NCBI chr11:103,061,401...103,089,727
Ensembl chr11:103,061,933...103,089,727
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G |
Fmod |
fibromodulin |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FMOD mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:133,964,992...133,976,018
Ensembl chr 1:133,964,992...133,976,015
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G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FN1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
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G |
Fnbp1 |
formin binding protein 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FNBP1 mRNA |
CTD |
PMID:24247028 |
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NCBI chr 2:30,916,218...31,032,046
Ensembl chr 2:30,916,218...31,032,020
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G |
Fos |
FBJ osteosarcoma oncogene |
increases expression multiple interactions affects activity |
ISO EXP |
deoxynivalenol results in increased expression of FOS mRNA deoxynivalenol inhibits the reaction [Cadmium Chloride results in decreased expression of FOS mRNA] Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of FOS protein] deoxynivalenol affects the activity of FOS protein deoxynivalenol results in increased expression of FOS mRNA; deoxynivalenol results in increased expression of FOS protein |
CTD |
PMID:10662601 PMID:15371230 PMID:15681167 PMID:19360757 PMID:21873375 PMID:22968694 PMID:24937323 PMID:32416088 PMID:33309878 PMID:35314294 More...
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NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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G |
Fosb |
FBJ osteosarcoma oncogene B |
affects activity increases expression multiple interactions |
EXP ISO |
deoxynivalenol affects the activity of FOSB protein deoxynivalenol results in increased expression of FOSB mRNA [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSB mRNA |
CTD |
PMID:10662601 PMID:33309878 |
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NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
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G |
Fosl1 |
fos-like antigen 1 |
multiple interactions |
ISO |
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSL1 mRNA |
CTD |
PMID:33309878 |
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NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
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G |
Fosl2 |
fos-like antigen 2 |
multiple interactions increases expression affects activity |
EXP ISO |
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of FOSL2 mRNA] deoxynivalenol results in increased expression of FOSL2 mRNA; deoxynivalenol results in increased expression of FOSL2 protein [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSL2 mRNA deoxynivalenol affects the activity of FOSL2 protein |
CTD |
PMID:10662601 PMID:15371230 PMID:15681167 PMID:33309878 PMID:33890134 |
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NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
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G |
Foxo1 |
forkhead box O1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of FOXO1 protein |
CTD |
PMID:15976193 |
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NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
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G |
Foxp3 |
forkhead box P3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of FOXP3 mRNA |
CTD |
PMID:27757495 |
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NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
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G |
Fuca1 |
fucosidase, alpha-L- 1, tissue |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FUCA1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:135,648,037...135,667,611
Ensembl chr 4:135,648,046...135,667,622
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G |
Fut1 |
fucosyltransferase 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of FUT1 mRNA |
CTD |
PMID:26763390 |
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NCBI chr 7:45,266,862...45,270,483
Ensembl chr 7:45,266,713...45,270,483
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G |
G3bp1 |
G3BP stress granule assembly factor 1 |
decreases phosphorylation increases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of G3BP1 protein deoxynivalenol results in increased phosphorylation of G3BP1 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr11:55,360,521...55,391,722
Ensembl chr11:55,360,511...55,395,664
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G |
G3bp2 |
G3BP stress granule assembly factor 2 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of G3BP2 protein |
CTD |
PMID:23352502 |
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NCBI chr 5:92,200,004...92,285,584
Ensembl chr 5:92,200,005...92,231,578
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G |
Gabpa |
GA repeat binding protein, alpha |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of GABPA protein |
CTD |
PMID:33890134 |
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NCBI chr16:84,631,795...84,660,671
Ensembl chr16:84,631,813...84,660,667
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G |
Gadd45a |
growth arrest and DNA-damage-inducible 45 alpha |
increases expression |
ISO |
deoxynivalenol results in increased expression of GADD45A mRNA |
CTD |
PMID:30169763 PMID:31863870 |
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NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
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G |
Galnt1 |
polypeptide N-acetylgalactosaminyltransferase 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of GALNT1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr18:24,338,401...24,419,873
Ensembl chr18:24,338,401...24,419,875
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G |
Galp |
galanin-like peptide |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of GALP mRNA; deoxynivalenol results in increased expression of GALP protein GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL11 protein]; GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL6 protein] |
CTD |
PMID:32738333 |
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NCBI chr 7:6,200,089...6,219,136
Ensembl chr 7:6,200,089...6,219,136
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G |
Galr2 |
galanin receptor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of GALR2 mRNA |
CTD |
PMID:32738333 |
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NCBI chr11:116,170,520...116,174,776
Ensembl chr11:116,171,765...116,174,764
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G |
Galr3 |
galanin receptor 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of GALR3 mRNA |
CTD |
PMID:32738333 |
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NCBI chr15:78,926,085...78,927,758
Ensembl chr15:78,926,085...78,927,758
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G |
Gatad2a |
GATA zinc finger domain containing 2A |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of GATAD2A protein |
CTD |
PMID:23352502 |
|
NCBI chr 8:70,359,719...70,450,093
Ensembl chr 8:70,359,726...70,449,034
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G |
Gcg |
glucagon |
multiple interactions increases expression increases secretion |
EXP |
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form] deoxynivalenol results in increased expression of GCG protein |
CTD |
PMID:25787141 PMID:28633506 |
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NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions decreases expression |
EXP ISO |
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of GCLC mRNA] Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GCLC protein] |
CTD |
PMID:35817260 PMID:37419272 |
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NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
increases expression |
EXP |
deoxynivalenol results in increased expression of GCLM mRNA |
CTD |
PMID:34400200 |
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NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Gdf5 |
growth differentiation factor 5 |
increases expression |
ISO |
deoxynivalenol results in increased expression of GDF5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:155,782,943...155,787,204
Ensembl chr 2:155,782,943...155,787,287
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G |
Gh |
growth hormone |
multiple interactions decreases secretion decreases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; deoxynivalenol results in decreased expression of and results in decreased secretion of GH1 protein; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein] deoxynivalenol results in decreased secretion of GH1 protein |
CTD |
PMID:26141394 PMID:32738333 PMID:34673182 |
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NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
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G |
Ghr |
growth hormone receptor |
affects expression |
ISO |
deoxynivalenol affects the expression of GHR mRNA |
CTD |
PMID:34673182 |
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NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
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G |
Ghrh |
growth hormone releasing hormone |
increases expression |
ISO |
deoxynivalenol results in increased expression of GHRH mRNA |
CTD |
PMID:34673182 |
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NCBI chr 2:157,171,416...157,190,645
Ensembl chr 2:157,171,417...157,189,426
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G |
Gip |
gastric inhibitory polypeptide |
increases expression |
EXP |
deoxynivalenol results in increased expression of GIP protein |
CTD |
PMID:28633506 |
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NCBI chr11:95,915,358...95,921,657
Ensembl chr11:95,915,371...95,921,657
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G |
Gkap1 |
G kinase anchoring protein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of GKAP1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:58,381,160...58,422,691
Ensembl chr13:58,381,160...58,423,513
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G |
Gldn |
gliomedin |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of GLDN mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:54,193,770...54,249,061
Ensembl chr 9:54,193,770...54,249,070
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G |
Got1 |
glutamic-oxaloacetic transaminase 1, soluble |
increases activity multiple interactions |
EXP |
deoxynivalenol results in increased activity of GOT1 protein BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GOT1 protein] |
CTD |
PMID:36602574 |
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NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
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G |
Gp1bb |
glycoprotein Ib, beta polypeptide |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of GP1BB protein |
CTD |
PMID:23811945 |
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NCBI chr16:18,439,069...18,441,153
Ensembl chr16:18,439,067...18,441,153
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G |
Gpkow |
G patch domain and KOW motifs |
increases expression |
ISO |
deoxynivalenol results in increased expression of GPKOW mRNA |
CTD |
PMID:31863870 |
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NCBI chr X:7,563,373...7,576,500
Ensembl chr X:7,563,370...7,576,501
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G |
Gpn1 |
GPN-loop GTPase 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of GPN1 protein |
CTD |
PMID:23352502 |
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NCBI chr 5:31,652,085...31,670,250
Ensembl chr 5:31,652,085...31,670,248
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G |
Gpt |
glutamic pyruvic transaminase, soluble |
multiple interactions increases expression increases activity |
EXP ISO |
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased activity of GPT protein] Bentonite inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of GPT protein] |
CTD |
PMID:25445755 PMID:26115597 PMID:34400200 PMID:35925383 PMID:36602574 |
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NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
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G |
Gpx1 |
glutathione peroxidase 1 |
increases phosphorylation increases expression |
EXP |
deoxynivalenol results in increased phosphorylation of GPX1 protein deoxynivalenol results in increased expression of GPX1 mRNA |
CTD |
PMID:23811945 PMID:34400200 |
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NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO EXP |
deoxynivalenol results in decreased expression of GPX4 mRNA Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of GPX4 protein] Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GPX4 protein] |
CTD |
PMID:37419272 PMID:38040082 |
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NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of GREM1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991
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G |
Gsdmd |
gasdermin D |
multiple interactions increases expression |
EXP |
deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD protein]; deoxynivalenol results in increased expression of and results in increased cleavage of GSDMD protein; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD protein] deoxynivalenol results in increased expression of GSDMD mRNA; deoxynivalenol results in increased expression of GSDMD protein |
CTD |
PMID:35925383 PMID:36309173 |
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NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
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G |
Gsdme |
gasdermin E |
multiple interactions |
EXP ISO |
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein]; deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein [GSDME protein co-treated with deoxynivalenol] results in increased secretion of IL1B protein; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of GSDME protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of GSDME protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of GSDME protein; GSDME protein inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]; GSDME protein promotes the reaction [deoxynivalenol results in increased secretion of IL6 protein] |
CTD |
PMID:35925383 |
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NCBI chr 6:50,167,013...50,240,837
Ensembl chr 6:50,165,868...50,240,842
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of GSK3B protein |
CTD |
PMID:15976193 |
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NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
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G |
Gss |
glutathione synthetase |
multiple interactions increases expression |
ISO |
Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GSS protein]; Resveratrol promotes the reaction [deoxynivalenol results in increased expression of GSS protein] deoxynivalenol results in increased expression of GSS mRNA |
CTD |
PMID:37419272 |
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NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
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G |
H1f0 |
H1.0 linker histone |
increases expression |
ISO |
deoxynivalenol results in increased expression of H1-0 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:78,912,412...78,914,704
Ensembl chr15:78,912,650...78,914,704
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G |
H1f10 |
H1.10 linker histone |
increases expression |
ISO |
deoxynivalenol results in increased expression of H1-10 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:87,957,403...87,958,464
Ensembl chr 6:87,957,403...87,958,619
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G |
H1f2 |
H1.2 linker histone, cluster member |
increases expression |
ISO |
deoxynivalenol results in increased expression of H1-2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350
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G |
H1f5 |
H1.5 linker histone, cluster member |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of H1F5 protein |
CTD |
PMID:23352502 |
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NCBI chr13:21,964,002...21,964,795
Ensembl chr13:21,964,053...21,964,795
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G |
H2bc14 |
H2B clustered histone 14 |
increases expression |
ISO |
deoxynivalenol results in increased expression of H2BC5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:21,906,214...21,906,696
Ensembl chr13:21,906,214...21,906,737
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of HAPLN1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771
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G |
Haus2 |
HAUS augmin-like complex, subunit 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of HAUS2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:120,439,863...120,452,041
Ensembl chr 2:120,439,864...120,452,041
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G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of HBA protein |
CTD |
PMID:23811945 |
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NCBI chr11:32,233,672...32,234,486
Ensembl chr11:32,233,511...32,234,465
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G |
Hbb-b1 |
hemoglobin, beta adult major chain |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of HBB-B1 protein |
CTD |
PMID:23811945 |
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G |
Hck |
hemopoietic cell kinase |
increases phosphorylation affects response to substance multiple interactions |
ISO EXP |
deoxynivalenol results in increased phosphorylation of HCK protein HCK protein affects the susceptibility to deoxynivalenol 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; HCK protein affects the reaction [deoxynivalenol results in increased expression of TNF protein] |
CTD |
PMID:15772366 PMID:20181660 PMID:22491426 |
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NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361
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G |
Hdac1 |
histone deacetylase 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of HDAC1 protein |
CTD |
PMID:23352502 |
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NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506
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G |
Hdac2 |
histone deacetylase 2 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of HDAC2 protein |
CTD |
PMID:23352502 |
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NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
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G |
Hdgf |
heparin binding growth factor |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of HDGF protein |
CTD |
PMID:23811945 |
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NCBI chr 3:87,813,844...87,823,439
Ensembl chr 3:87,813,628...87,823,439
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G |
Hemgn |
hemogen |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of HEMGN protein |
CTD |
PMID:23811945 |
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NCBI chr 4:46,393,989...46,404,183
Ensembl chr 4:46,393,989...46,413,506
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G |
Hif1a |
hypoxia inducible factor 1, alpha subunit |
multiple interactions increases expression |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of HIF1A mRNA] deoxynivalenol results in increased expression of HIF1A protein Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of HIF1A protein] |
CTD |
PMID:34677630 PMID:38040082 |
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NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
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G |
Hinfp |
histone H4 transcription factor |
increases expression |
ISO |
deoxynivalenol results in increased expression of HINFP protein |
CTD |
PMID:33890134 |
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NCBI chr 9:44,201,509...44,217,003
Ensembl chr 9:44,203,737...44,216,968
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G |
Hint1 |
histidine triad nucleotide binding protein 1 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of HINT1 mRNA |
CTD |
PMID:15371230 |
|
NCBI chr11:54,757,209...54,761,332
Ensembl chr11:54,757,209...54,761,327
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G |
Hlx |
H2.0-like homeobox |
increases expression |
ISO |
deoxynivalenol results in increased expression of HLX mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-Coenzyme A reductase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of HMGCR mRNA |
CTD |
PMID:22982764 |
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NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
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G |
Hmox1 |
heme oxygenase 1 |
decreases expression multiple interactions increases expression decreases response to substance |
ISO EXP |
deoxynivalenol results in decreased expression of HMOX1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of HMOX1 mRNA] deoxynivalenol results in increased expression of HMOX1 mRNA; deoxynivalenol results in increased expression of HMOX1 protein HMOX1 protein results in decreased susceptibility to deoxynivalenol Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of HMOX1 protein] |
CTD |
PMID:24355168 PMID:26763390 PMID:31034930 PMID:31863870 PMID:34400200 PMID:34677630 PMID:35314294 PMID:35817260 PMID:38040082 More...
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hnf4a |
hepatic nuclear factor 4, alpha |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of HNF4 mRNA; deoxynivalenol results in increased expression of HNF4A mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA |
CTD |
PMID:28865950 PMID:35314294 |
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NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
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G |
Hoxa7 |
homeobox A7 |
multiple interactions increases expression |
ISO |
AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of HOXA7 mRNA] |
CTD |
PMID:19438726 |
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NCBI chr 6:52,191,471...52,198,757
Ensembl chr 6:52,191,471...52,198,834
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G |
Hsp90ab1 |
heat shock protein 90 alpha (cytosolic), class B member 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of HSP90AB1 protein |
CTD |
PMID:23811945 |
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NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
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G |
Hspa1l |
heat shock protein 1-like |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of HSPA1L protein |
CTD |
PMID:33890134 |
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NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
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G |
Hspa5 |
heat shock protein 5 |
multiple interactions increases phosphorylation decreases expression |
EXP ISO |
calpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein]; deoxynivalenol results in increased degradation of and results in decreased expression of HSPA5 protein; phenylalanyl-glycyl-NHO-Bz inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein] deoxynivalenol results in increased phosphorylation of HSPA5 protein deoxynivalenol results in decreased expression of HSPA5 mRNA |
CTD |
PMID:10652249 PMID:19336499 PMID:20682335 PMID:23811945 PMID:24356939 |
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NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
Hspa8 |
heat shock protein 8 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of HSPA8 protein |
CTD |
PMID:23811945 |
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NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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G |
Hsph1 |
heat shock 105kDa/110kDa protein 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of HSPH1 protein |
CTD |
PMID:23352502 |
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NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
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G |
Hyls1 |
HYLS1, centriolar and ciliogenesis associated |
increases expression |
ISO |
deoxynivalenol results in increased expression of HYLS1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 9:35,472,117...35,481,365
Ensembl chr 9:35,472,116...35,481,694
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of ICAM1 mRNA; deoxynivalenol results in increased expression of ICAM1 protein deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein] |
CTD |
PMID:19549553 PMID:21074547 PMID:34400200 |
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NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Id1 |
inhibitor of DNA binding 1, HLH protein |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ID1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
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G |
Ifitm3 |
interferon induced transmembrane protein 3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of IFITM3 protein |
CTD |
PMID:33890134 |
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NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683
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G |
Ifna1 |
interferon alpha 1 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of IFNA1 mRNA |
CTD |
PMID:17090620 |
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NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893
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G |
Ifnar1 |
interferon (alpha and beta) receptor 1 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of IFNAR1 mRNA |
CTD |
PMID:17090620 |
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NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
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G |
Ifnb1 |
interferon beta 1, fibroblast |
multiple interactions increases expression |
EXP |
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] deoxynivalenol results in increased expression of IFNB1 mRNA |
CTD |
PMID:14644621 PMID:17090620 PMID:19857559 |
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NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011
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G |
Ifng |
interferon gamma |
affects expression multiple interactions increases expression |
ISO EXP |
deoxynivalenol affects the expression of IFNG mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] deoxynivalenol results in increased expression of IFNG mRNA; deoxynivalenol results in increased expression of IFNG protein [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IFNG protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IFNG protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA] |
CTD |
PMID:9194413 PMID:9707511 PMID:14644621 PMID:17090620 PMID:17166736 PMID:19549553 PMID:20702593 PMID:22968694 PMID:24937323 PMID:25766886 PMID:28935500 PMID:32416088 More...
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NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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G |
Ifngr1 |
interferon gamma receptor 1 |
multiple interactions decreases expression |
ISO EXP |
deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein] deoxynivalenol results in decreased expression of IFNGR1 mRNA |
CTD |
PMID:17090620 PMID:19549553 |
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NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions increases expression decreases expression |
EXP ISO |
deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGF1 mRNA] deoxynivalenol results in increased expression of IGF1 mRNA deoxynivalenol results in decreased expression of IGF1 protein |
CTD |
PMID:19805407 PMID:32738333 |
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NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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G |
Igfals |
insulin-like growth factor binding protein, acid labile subunit |
decreases expression increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in decreased expression of IGFALS mRNA; deoxynivalenol results in decreased expression of IGFALS protein deoxynivalenol results in increased expression of IGFALS mRNA deoxynivalenol inhibits the reaction [Glutathione results in increased expression of IGFALS mRNA] |
CTD |
PMID:19625342 PMID:19805407 PMID:23298694 PMID:32738333 |
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NCBI chr17:25,096,818...25,100,985
Ensembl chr17:25,084,971...25,100,984
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions |
EXP |
deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGFBP3 mRNA] |
CTD |
PMID:19805407 |
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NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of IGFBP6 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946
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G |
Il10 |
interleukin 10 |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of IL10 mRNA alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of TNF mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein]]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of SOCS3 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of SOCS3 protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:9194413 PMID:9707511 PMID:22968694 PMID:38432439 |
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NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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G |
Il10rb |
interleukin 10 receptor, beta |
increases expression |
EXP |
deoxynivalenol results in increased expression of IL10RB mRNA |
CTD |
PMID:22968694 |
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NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722
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G |
Il11 |
interleukin 11 |
increases expression affects expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of IL11 mRNA deoxynivalenol affects the expression of IL11 mRNA deoxynivalenol results in increased expression of IL11 mRNA; deoxynivalenol results in increased expression of IL11 protein GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL11 protein] Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL11 mRNA] |
CTD |
PMID:15371230 PMID:15681167 PMID:32738333 PMID:34673182 |
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NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858
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G |
Il12a |
interleukin 12a |
increases expression |
EXP ISO |
deoxynivalenol results in increased expression of IL12A mRNA |
CTD |
PMID:9707511 PMID:27757495 |
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NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
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G |
Il12b |
interleukin 12b |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of IL12B mRNA [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein |
CTD |
PMID:9194413 PMID:9707511 PMID:28935500 |
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NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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G |
Il13 |
interleukin 13 |
multiple interactions |
EXP |
deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL13 protein] |
CTD |
PMID:33170220 |
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NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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G |
Il15 |
interleukin 15 |
increases expression |
ISO |
deoxynivalenol results in increased expression of IL15 mRNA |
CTD |
PMID:27757495 |
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NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
EXP |
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL17A protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL17A protein] |
CTD |
PMID:28935500 PMID:32416088 |
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NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
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G |
Il18 |
interleukin 18 |
decreases expression multiple interactions increases secretion increases expression |
EXP |
deoxynivalenol results in decreased expression of IL18 mRNA acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL18 protein] deoxynivalenol results in increased expression of IL18 mRNA; deoxynivalenol results in increased expression of IL18 protein |
CTD |
PMID:22968694 PMID:35925383 PMID:36309173 |
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NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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G |
Il18rap |
interleukin 18 receptor accessory protein |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of IL18RAP mRNA |
CTD |
PMID:22968694 |
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NCBI chr 1:40,554,548...40,590,867
Ensembl chr 1:40,554,522...40,590,865
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G |
Il1a |
interleukin 1 alpha |
increases expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of IL1A mRNA Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL1A mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA] |
CTD |
PMID:15371230 PMID:15681167 PMID:16009389 PMID:32738333 |
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NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
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G |
Il1b |
interleukin 1 beta |
increases expression increases secretion multiple interactions decreases expression |
ISO EXP |
deoxynivalenol results in increased expression of IL1B mRNA; deoxynivalenol results in increased expression of IL1B protein deoxynivalenol results in increased secretion of IL1B protein GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL1B protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; [GSDME protein co-treated with deoxynivalenol] results in increased secretion of IL1B protein; [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL1B protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL1B protein]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL1B protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA] deoxynivalenol results in decreased expression of IL1B mRNA |
CTD |
PMID:9194413 PMID:9707511 PMID:10344227 PMID:12604842 PMID:12773775 PMID:15371230 PMID:15681167 PMID:16009389 PMID:16364386 PMID:16687389 PMID:18308354 PMID:18433975 PMID:18614267 PMID:20702593 PMID:21873375 PMID:22454431 PMID:22968694 PMID:24793808 PMID:25392278 PMID:25549547 PMID:25766886 PMID:28935500 PMID:31034930 PMID:32738333 PMID:33170220 PMID:33890134 PMID:34400200 PMID:34673182 PMID:35090964 PMID:35381244 PMID:35817260 PMID:35925383 PMID:36309173 PMID:36602574 PMID:38432439 More...
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il1f10 |
interleukin 1 family, member 10 |
increases expression |
EXP |
deoxynivalenol results in increased expression of IL1F10 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 2:24,177,095...24,184,236
Ensembl chr 2:24,181,208...24,183,832
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G |
Il1r1 |
interleukin 1 receptor, type I |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of IL1R1 mRNA IL1R1 protein affects the susceptibility to [Lipopolysaccharides co-treated with deoxynivalenol] |
CTD |
PMID:12773775 PMID:22968694 |
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NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
EXP |
deoxynivalenol results in increased expression of IL1RL1 mRNA |
CTD |
PMID:26304032 |
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NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
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G |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
EXP |
deoxynivalenol results in increased expression of IL1RN mRNA |
CTD |
PMID:22968694 |
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NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
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G |
Il2 |
interleukin 2 |
affects secretion increases expression increases stability multiple interactions affects expression |
EXP ISO |
deoxynivalenol affects the secretion of IL2 protein deoxynivalenol results in increased expression of IL2 mRNA deoxynivalenol results in increased stability of IL2 mRNA deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein] deoxynivalenol affects the expression of IL2 mRNA |
CTD |
PMID:8560498 PMID:8658534 PMID:9194413 PMID:9439728 PMID:9707511 PMID:17166736 More...
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NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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G |
Il22ra2 |
interleukin 22 receptor, alpha 2 |
increases expression |
EXP |
deoxynivalenol results in increased expression of IL22RA2 mRNA |
CTD |
PMID:22968694 |
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NCBI chr10:19,497,776...19,510,429
Ensembl chr10:19,497,746...19,510,429
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G |
Il23a |
interleukin 23, alpha subunit p19 |
increases expression |
EXP |
deoxynivalenol results in increased expression of IL23A mRNA |
CTD |
PMID:22968694 |
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NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
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G |
Il33 |
interleukin 33 |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of IL33 mRNA; deoxynivalenol results in increased expression of IL33 protein deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL33 protein]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 mRNA]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 protein] |
CTD |
PMID:26304032 PMID:33170220 |
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NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
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G |
Il36g |
interleukin 36G |
increases expression |
ISO |
deoxynivalenol results in increased expression of IL36G protein |
CTD |
PMID:33890134 |
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NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580
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G |
Il4 |
interleukin 4 |
increases expression multiple interactions affects secretion |
ISO EXP |
deoxynivalenol results in increased expression of IL4 mRNA deoxynivalenol results in increased expression of IL4 mRNA; deoxynivalenol results in increased expression of IL4 protein deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL4 protein] deoxynivalenol affects the secretion of IL4 protein |
CTD |
PMID:8560498 PMID:8658534 PMID:9194413 PMID:9707511 PMID:22846391 PMID:24937323 PMID:33170220 More...
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NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
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G |
Il5 |
interleukin 5 |
affects secretion increases expression multiple interactions |
EXP |
deoxynivalenol affects the secretion of IL5 protein deoxynivalenol results in increased expression of IL5 mRNA deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL5 protein] |
CTD |
PMID:8560498 PMID:8658534 PMID:33170220 |
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NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
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G |
Il6 |
interleukin 6 |
decreases expression increases secretion multiple interactions increases expression increases stability |
ISO EXP |
deoxynivalenol results in decreased expression of IL6 mRNA deoxynivalenol results in increased secretion of IL6 protein [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL6 mRNA; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; GSDME protein promotes the reaction [deoxynivalenol results in increased secretion of IL6 protein] GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL6 protein] deoxynivalenol results in increased expression of IL6 mRNA; deoxynivalenol results in increased expression of IL6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL6 protein; [Docosahexaenoic Acids co-treated with Eicosapentaenoic Acid] inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL6 protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Fish Oils inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Indomethacin inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA] deoxynivalenol results in increased stability of IL6 mRNA |
CTD |
PMID:9194413 PMID:9707511 PMID:10344227 PMID:11295263 PMID:11922776 PMID:12604842 PMID:12649040 PMID:14644621 PMID:14690764 PMID:15173396 PMID:15371230 PMID:15570035 PMID:15681167 PMID:16009389 PMID:16364386 PMID:16424113 PMID:16524712 PMID:16687389 PMID:17090620 PMID:18433975 PMID:18614267 PMID:19336499 PMID:19625342 PMID:20702593 PMID:21873375 PMID:22454431 PMID:22968694 PMID:24793808 PMID:24937323 PMID:27757495 PMID:28935500 PMID:31034930 PMID:32416088 PMID:32738333 PMID:33170220 PMID:34400200 PMID:34673182 PMID:35090964 PMID:35381244 PMID:35817260 PMID:35925383 PMID:36309173 PMID:36602574 More...
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Il7 |
interleukin 7 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of IL7 mRNA |
CTD |
PMID:22968694 |
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NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820
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G |
Il9 |
interleukin 9 |
multiple interactions |
EXP |
deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL9 protein] |
CTD |
PMID:33170220 |
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NCBI chr13:56,627,090...56,630,070
Ensembl chr13:56,627,090...56,630,059
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G |
Inpp5d |
inositol polyphosphate-5-phosphatase D |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of INPP5D protein |
CTD |
PMID:23352502 |
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NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
EXP |
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRAK1 protein] |
CTD |
PMID:26961612 |
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NCBI chr X:73,057,520...73,067,527
Ensembl chr X:73,057,520...73,067,524
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G |
Irf2bp2 |
interferon regulatory factor 2 binding protein 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of IRF2BP2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:127,315,035...127,320,725
Ensembl chr 8:127,315,035...127,320,725
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G |
Ist1 |
increased sodium tolerance 1 homolog (yeast) |
increases expression |
ISO |
deoxynivalenol results in increased expression of IST1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:110,397,953...110,419,929
Ensembl chr 8:110,397,957...110,419,892
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G |
Itga10 |
integrin, alpha 10 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ITGA10 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:96,552,900...96,571,835
Ensembl chr 3:96,552,900...96,571,835
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G |
Itgb2 |
integrin beta 2 |
increases expression |
EXP |
deoxynivalenol results in increased expression of ITGB2 mRNA |
CTD |
PMID:22968694 |
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NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
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G |
Itgbl1 |
integrin, beta-like 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ITGBL1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:123,897,331...124,215,173
Ensembl chr14:123,897,383...124,213,030
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G |
Itih5 |
inter-alpha-trypsin inhibitor, heavy chain 5 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of ITIH5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:10,158,354...10,261,340
Ensembl chr 2:10,158,382...10,261,340
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G |
Jak1 |
Janus kinase 1 |
increases expression increases phosphorylation |
EXP |
deoxynivalenol results in increased expression of JAK1 mRNA deoxynivalenol results in increased phosphorylation of JAK1 protein |
CTD |
PMID:22454431 PMID:36602574 |
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NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
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G |
Jak2 |
Janus kinase 2 |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of JAK2 mRNA alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA] |
CTD |
PMID:22454431 PMID:38432439 |
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NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
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G |
Jun |
jun proto-oncogene |
multiple interactions increases phosphorylation increases activity increases expression affects localization affects activity |
ISO EXP |
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of and results in increased phosphorylation of JUN protein deoxynivalenol results in increased phosphorylation of JUN protein deoxynivalenol results in increased activity of JUN protein deoxynivalenol results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of JUN protein deoxynivalenol affects the localization of JUN protein deoxynivalenol affects the activity of JUN protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUN protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of JUN protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein] |
CTD |
PMID:10662601 PMID:12604842 PMID:15371230 PMID:15681167 PMID:15772366 PMID:16424113 PMID:19360757 PMID:23352502 PMID:23792671 PMID:24937323 PMID:32416088 PMID:33309878 PMID:33890134 More...
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NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Junb |
jun B proto-oncogene |
multiple interactions increases expression increases activity affects activity |
EXP ISO |
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUNB protein] deoxynivalenol results in increased expression of JUNB mRNA [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUNB mRNA deoxynivalenol affects the activity of JUNB protein |
CTD |
PMID:10662601 PMID:15371230 PMID:15681167 PMID:15772366 PMID:33309878 |
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NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
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G |
Jund |
jun D proto-oncogene |
affects activity multiple interactions affects localization increases activity increases expression |
EXP ISO |
deoxynivalenol affects the activity of JUND protein [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUND mRNA deoxynivalenol affects the localization of JUND protein deoxynivalenol results in increased activity of JUND protein deoxynivalenol results in increased expression of JUND mRNA; deoxynivalenol results in increased expression of JUND protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUND protein] |
CTD |
PMID:10662601 PMID:12604842 PMID:15772366 PMID:22846391 PMID:33309878 PMID:33890134 More...
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NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
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G |
Kat2a |
K(lysine) acetyltransferase 2A |
multiple interactions |
ISO |
KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form] |
CTD |
PMID:30286430 |
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NCBI chr11:100,595,572...100,603,293
Ensembl chr11:100,595,572...100,603,291
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G |
Kat2b |
K(lysine) acetyltransferase 2B |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of KAT2B protein KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form] |
CTD |
PMID:30286430 |
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NCBI chr17:53,873,802...53,979,749
Ensembl chr17:53,873,889...53,979,748
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G |
Kbtbd11 |
kelch repeat and BTB (POZ) domain containing 11 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of KBTBD11 protein |
CTD |
PMID:23811945 |
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NCBI chr 8:15,059,408...15,083,333
Ensembl chr 8:15,061,025...15,083,333
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G |
Kcnmb4 |
potassium large conductance calcium-activated channel, subfamily M, beta member 4 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of KCNMB4 mRNA |
CTD |
PMID:26763390 |
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NCBI chr10:116,251,951...116,309,787
Ensembl chr10:116,253,766...116,309,783
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G |
Kdelr3 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of KDELR3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:79,400,609...79,411,940
Ensembl chr15:79,400,612...79,411,940
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G |
Kdm4b |
lysine (K)-specific demethylase 4B |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of KDM4B protein |
CTD |
PMID:23811945 |
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NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870
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G |
Keap1 |
kelch-like ECH-associated protein 1 |
decreases expression multiple interactions increases expression |
EXP |
deoxynivalenol results in decreased expression of KEAP1 mRNA Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of KEAP1 protein] |
CTD |
PMID:34400200 PMID:38040082 |
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NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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G |
Khdc4 |
KH domain containing 4, pre-mRNA splicing factor |
increases expression |
ISO |
deoxynivalenol results in increased expression of KHDC4 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 3:88,593,087...88,620,240
Ensembl chr 3:88,593,110...88,620,231
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G |
Khdrbs3 |
KH domain containing, RNA binding, signal transduction associated 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of KHDRBS3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr15:68,800,155...68,973,064
Ensembl chr15:68,800,269...68,973,060
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G |
Kif11 |
kinesin family member 11 |
increases expression |
ISO |
deoxynivalenol results in increased expression of KIF11 mRNA |
CTD |
PMID:31863870 |
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NCBI chr19:37,364,830...37,410,311
Ensembl chr19:37,364,851...37,410,307
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G |
Kif2c |
kinesin family member 2C |
increases expression |
ISO |
deoxynivalenol results in increased expression of KIF2C mRNA |
CTD |
PMID:31863870 |
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NCBI chr 4:117,016,830...117,039,821
Ensembl chr 4:117,016,836...117,039,836
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G |
Kitl |
kit ligand |
increases expression |
ISO |
deoxynivalenol results in increased expression of KITLG mRNA |
CTD |
PMID:27757495 PMID:31863870 |
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NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
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G |
Klf4 |
Kruppel-like transcription factor 4 (gut) |
affects localization affects expression |
ISO |
deoxynivalenol affects the localization of KLF4 protein deoxynivalenol affects the expression of KLF4 protein |
CTD |
PMID:33890134 |
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NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
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G |
Klhl30 |
kelch-like 30 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of KLHL30 mRNA |
CTD |
PMID:26763390 |
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NCBI chr 1:91,278,795...91,290,126
Ensembl chr 1:91,278,738...91,290,138
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G |
Kmt2a |
lysine (K)-specific methyltransferase 2A |
multiple interactions increases expression |
ISO |
AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]; deoxynivalenol promotes the reaction [SP1 protein binds to KMT2A promoter]; SP1 protein promotes the reaction [deoxynivalenol results in increased expression of KMT2A mRNA] |
CTD |
PMID:19438726 |
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NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
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G |
Krt18 |
keratin 18 |
increases expression |
ISO |
deoxynivalenol results in increased expression of KRT18 protein |
CTD |
PMID:33890134 |
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NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
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G |
Krt20 |
keratin 20 |
multiple interactions decreases expression |
EXP |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of KRT20 protein] |
CTD |
PMID:34506767 |
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NCBI chr11:99,319,211...99,328,979
Ensembl chr11:99,319,229...99,328,976
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G |
Lamb1 |
laminin B1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of LAMB1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:31,315,230...31,379,643
Ensembl chr12:31,315,233...31,379,643
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G |
Larp7 |
La ribonucleoprotein 7, transcriptional regulator |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of LARP7 protein |
CTD |
PMID:23352502 |
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NCBI chr 3:127,330,363...127,346,998
Ensembl chr 3:127,330,363...127,346,998
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G |
Lcn3 |
lipocalin 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of LCN1 protein |
CTD |
PMID:33890134 |
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NCBI chr 2:25,655,545...25,658,110
Ensembl chr 2:25,655,581...25,658,111
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
increases phosphorylation affects phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of LCP1 protein deoxynivalenol affects the phosphorylation of LCP1 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr14:75,368,570...75,468,282
Ensembl chr14:75,368,541...75,468,282
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G |
Lgals3bp |
lectin, galactoside-binding, soluble, 3 binding protein |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of LGALS3BP protein |
CTD |
PMID:33890134 |
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NCBI chr11:118,283,573...118,292,787
Ensembl chr11:118,283,577...118,292,918
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G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
multiple interactions decreases expression |
EXP |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LGR5 protein] |
CTD |
PMID:34506767 |
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NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions |
EXP |
[Colforsin co-treated with deoxynivalenol] results in increased expression of LHCGR mRNA |
CTD |
PMID:26783879 |
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NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418
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G |
Lig1 |
ligase I, DNA, ATP-dependent |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of LIG1 protein |
CTD |
PMID:23811945 |
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NCBI chr 7:13,011,101...13,045,351
Ensembl chr 7:13,011,239...13,045,350
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G |
Lipa |
lysosomal acid lipase A |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of LIPA protein |
CTD |
PMID:33890134 |
|
NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
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G |
Lmna |
lamin A |
affects phosphorylation decreases phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of LMNA protein deoxynivalenol results in decreased phosphorylation of LMNA protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263
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G |
Lmnb1 |
lamin B1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of LMNB1 protein |
CTD |
PMID:23811945 |
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NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
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G |
Lmo2 |
LIM domain only 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of LMO2 mRNA |
CTD |
PMID:26763390 |
|
NCBI chr 2:103,788,309...103,812,223
Ensembl chr 2:103,788,331...103,812,223
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G |
Loxl3 |
lysyl oxidase-like 3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of LOXL3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:83,011,186...83,029,547
Ensembl chr 6:83,011,154...83,029,543
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G |
Lpcat3 |
lysophosphatidylcholine acyltransferase 3 |
multiple interactions decreases expression |
EXP |
Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of LPCAT3 protein] |
CTD |
PMID:38040082 |
|
NCBI chr 6:124,639,887...124,681,142
Ensembl chr 6:124,639,990...124,681,381
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G |
Lpxn |
leupaxin |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of LPXN protein |
CTD |
PMID:23352502 |
|
NCBI chr19:12,773,251...12,811,177
Ensembl chr19:12,773,557...12,811,171
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G |
Lsp1 |
lymphocyte specific 1 |
affects phosphorylation decreases expression increases phosphorylation |
EXP ISO |
deoxynivalenol affects the phosphorylation of LSP1 protein deoxynivalenol results in decreased expression of LSP1 mRNA deoxynivalenol results in increased phosphorylation of LSP1 protein |
CTD |
PMID:23352502 PMID:23811945 PMID:31863870 |
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NCBI chr 7:142,014,583...142,048,605
Ensembl chr 7:142,014,546...142,048,604
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G |
Lta |
lymphotoxin A |
increases expression |
EXP |
deoxynivalenol results in increased expression of LTA mRNA |
CTD |
PMID:22968694 |
|
NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327
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G |
Ltb |
lymphotoxin B |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of LTB mRNA |
CTD |
PMID:22968694 |
|
NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296
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|
G |
Ltbp2 |
latent transforming growth factor beta binding protein 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of LTBP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:84,829,986...84,923,581
Ensembl chr12:84,829,986...84,923,306
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G |
Lyz2 |
lysozyme 2 |
decreases expression multiple interactions |
EXP |
deoxynivalenol results in decreased expression of LYZ protein lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LYZ protein] |
CTD |
PMID:34506767 |
|
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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G |
Maff |
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) |
increases expression |
ISO |
deoxynivalenol results in increased expression of MAFF mRNA |
CTD |
PMID:24247028 |
|
NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
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G |
Mall |
mal, T cell differentiation protein-like |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MALL mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:127,546,310...127,571,817
Ensembl chr 2:127,546,306...127,571,852
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression decreases expression multiple interactions |
ISO EXP |
deoxynivalenol results in increased expression of MAP1LC3B mRNA deoxynivalenol results in decreased expression of MAP1LC3B protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]]; Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of MAP1LC3B protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA] |
CTD |
PMID:34677630 PMID:35381244 PMID:38040082 |
|
NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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G |
Map2k4 |
mitogen-activated protein kinase kinase 4 |
multiple interactions increases phosphorylation |
EXP |
Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:32416088 |
|
NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions increases phosphorylation |
ISO |
AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K6 protein] |
CTD |
PMID:20181660 |
|
NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions increases phosphorylation |
ISO |
AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP3K5 protein] |
CTD |
PMID:20181660 |
|
NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
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G |
Map4 |
microtubule-associated protein 4 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of MAP4 protein |
CTD |
PMID:23811945 |
|
NCBI chr 9:109,758,909...109,913,018
Ensembl chr 9:109,760,528...109,913,023
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation |
EXP ISO |
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein] [deoxynivalenol results in increased phosphorylation of MAPK1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA] |
CTD |
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:15976193 PMID:16009389 PMID:16424113 PMID:17707346 PMID:18006205 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20633634 PMID:23352502 PMID:23811945 PMID:24937323 PMID:32416088 PMID:37705238 More...
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk12 |
mitogen-activated protein kinase 12 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MAPK12 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906
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G |
Mapk14 |
mitogen-activated protein kinase 14 |
multiple interactions increases expression increases phosphorylation |
ISO EXP |
deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK14 protein deoxynivalenol results in increased expression of MAPK14 mRNA deoxynivalenol results in increased phosphorylation of MAPK14 protein |
CTD |
PMID:15976193 PMID:16364386 PMID:20702593 |
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NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
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G |
Mapk3 |
mitogen-activated protein kinase 3 |
multiple interactions increases phosphorylation |
EXP ISO |
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein] [deoxynivalenol results in increased phosphorylation of MAPK3 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA] |
CTD |
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:15976193 PMID:16009389 PMID:16424113 PMID:17707346 PMID:18006205 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20633634 PMID:23352502 PMID:23811945 PMID:24937323 PMID:32416088 PMID:37705238 More...
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
decreases activity increases phosphorylation multiple interactions |
ISO EXP |
deoxynivalenol results in decreased activity of MAPK8 protein deoxynivalenol results in increased phosphorylation of MAPK8 protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein] [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein |
CTD |
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:16424113 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20708668 PMID:23352502 PMID:32416088 PMID:37705238 More...
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NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
decreases activity increases phosphorylation decreases phosphorylation decreases expression multiple interactions |
ISO EXP |
deoxynivalenol results in decreased activity of MAPK9 protein deoxynivalenol results in increased phosphorylation of MAPK9 protein deoxynivalenol results in decreased phosphorylation of MAPK9 protein deoxynivalenol results in decreased expression of MAPK9 mRNA 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein] [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK9 protein |
CTD |
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15371230 PMID:15570035 PMID:15772366 PMID:16424113 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20633634 PMID:20708668 PMID:23352502 PMID:23811945 More...
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NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of MARCKS protein |
CTD |
PMID:23811945 |
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NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916
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G |
Mdm2 |
transformed mouse 3T3 cell double minute 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MDM2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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G |
Mdm4 |
transformed mouse 3T3 cell double minute 4 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MDM4 mRNA |
CTD |
PMID:22846391 |
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NCBI chr 1:132,913,843...132,958,325
Ensembl chr 1:132,887,222...132,958,299
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G |
Meis3 |
Meis homeobox 3 |
decreases response to substance decreases expression |
ISO |
MEIS3 protein results in decreased susceptibility to deoxynivalenol deoxynivalenol results in decreased expression of MEIS3 mRNA |
CTD |
PMID:26763390 |
|
NCBI chr 7:15,908,684...15,920,435
Ensembl chr 7:15,909,015...15,920,429
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G |
Met |
met proto-oncogene |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of MET protein |
CTD |
PMID:23811945 |
|
NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
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G |
Mettl14 |
methyltransferase 14, N6-adenosine-methyltransferase subunit |
increases expression |
ISO |
deoxynivalenol results in increased expression of METTL14 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:123,161,944...123,179,639
Ensembl chr 3:123,161,946...123,179,757
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G |
Micall1 |
microtubule associated monooxygenase, calponin and LIM domain containing -like 1 |
decreases phosphorylation |
ISO |
deoxynivalenol results in decreased phosphorylation of MICALL1 protein |
CTD |
PMID:33890134 |
|
NCBI chr15:78,992,750...79,021,100
Ensembl chr15:78,993,098...79,021,100
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G |
Mir17hg |
Mir17 host gene (non-protein coding) |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of MIR17HG mRNA |
CTD |
PMID:23253260 |
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NCBI chr14:115,281,822...115,284,160
Ensembl chr14:115,278,211...115,284,162
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G |
Mir221 |
microRNA 221 |
multiple interactions |
ISO |
[Zearalenone co-treated with deoxynivalenol] results in decreased expression of MIR221 mRNA |
CTD |
PMID:35090964 |
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NCBI chr X:19,012,533...19,012,627
Ensembl chr X:19,012,533...19,012,627
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G |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
increases phosphorylation multiple interactions increases expression |
EXP ISO |
deoxynivalenol results in increased phosphorylation of MKI67 protein Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of MKI67 protein] deoxynivalenol results in increased expression of MKI67 mRNA |
CTD |
PMID:23352502 PMID:23811945 PMID:31863870 PMID:32416088 |
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NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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G |
Mknk2 |
MAP kinase-interacting serine/threonine kinase 2 |
affects phosphorylation decreases expression |
EXP ISO |
deoxynivalenol affects the phosphorylation of MKNK2 protein deoxynivalenol results in decreased expression of MKNK2 mRNA |
CTD |
PMID:23811945 PMID:31863870 |
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NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
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G |
Mmut |
methylmalonyl-Coenzyme A mutase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MMUT protein |
CTD |
PMID:33890134 |
|
NCBI chr17:41,245,576...41,272,880
Ensembl chr17:41,245,576...41,272,879
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G |
Mndal |
myeloid nuclear differentiation antigen like |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of MNDAL protein |
CTD |
PMID:23811945 |
|
NCBI chr 1:173,684,786...173,708,038
Ensembl chr 1:173,676,692...173,708,447
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G |
Mpo |
myeloperoxidase |
increases activity |
EXP |
deoxynivalenol results in increased activity of MPO protein |
CTD |
PMID:24937323 |
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NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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G |
Mrap2 |
melanocortin 2 receptor accessory protein 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MRAP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:87,026,293...87,066,104
Ensembl chr 9:87,026,359...87,066,098
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G |
Mrpl39 |
mitochondrial ribosomal protein L39 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MRPL39 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:84,515,068...84,532,261
Ensembl chr16:84,514,464...84,532,630
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G |
Mrps18b |
mitochondrial ribosomal protein S18B |
increases expression |
ISO |
deoxynivalenol results in increased expression of MRPS18B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr17:36,221,272...36,227,332
Ensembl chr17:36,221,271...36,227,281
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G |
Mrps22 |
mitochondrial ribosomal protein S22 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MRPS22 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:98,470,783...98,483,732
Ensembl chr 9:98,470,783...98,483,713
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G |
Mrps30 |
mitochondrial ribosomal protein S30 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MRPS30 mRNA |
CTD |
PMID:24247028 PMID:31863870 |
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NCBI chr13:118,516,646...118,523,788
Ensembl chr13:118,514,917...118,523,788
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G |
Mrps31 |
mitochondrial ribosomal protein S31 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MRPS31 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 8:22,901,356...22,919,685
Ensembl chr 8:22,901,377...22,919,681
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G |
Msx2 |
msh homeobox 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of MSX2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:53,620,917...53,626,816
Ensembl chr13:53,620,920...53,627,110
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G |
Mta3 |
metastasis associated 3 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of MTA3 protein |
CTD |
PMID:23352502 |
|
NCBI chr17:84,013,483...84,131,144
Ensembl chr17:84,013,592...84,128,945
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G |
Mtdh |
metadherin |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of LYRIC protein |
CTD |
PMID:23352502 |
|
NCBI chr15:34,082,613...34,143,683
Ensembl chr15:34,082,840...34,145,770
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G |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MTHFD2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:83,282,686...83,302,926
Ensembl chr 6:83,282,673...83,302,890
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G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation multiple interactions |
EXP |
deoxynivalenol results in decreased phosphorylation of MTOR protein lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:34506767 |
|
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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G |
Mtrex |
Mtr4 exosome RNA helicase |
increases expression |
ISO |
deoxynivalenol results in increased expression of MTREX mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:113,004,306...113,063,914
Ensembl chr13:113,003,952...113,063,932
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G |
Muc16 |
mucin 16 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of MUC16 protein |
CTD |
PMID:23811945 |
|
NCBI chr 9:18,406,741...18,586,117
Ensembl chr 9:18,406,751...18,585,826
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G |
Muc2 |
mucin 2 |
decreases expression multiple interactions |
EXP |
deoxynivalenol results in decreased expression of MUC2 protein lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of MUC2 protein] |
CTD |
PMID:34506767 |
|
NCBI chr 7:141,276,583...141,308,428
Ensembl chr 7:141,276,583...141,308,430
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G |
Muc5ac |
mucin 5, subtypes A and C, tracheobronchial/gastric |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of MUC5AC mRNA deoxynivalenol results in increased expression of and results in increased secretion of MUC5AC protein |
CTD |
PMID:24496642 |
|
NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
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G |
Muc5b |
mucin 5, subtype B, tracheobronchial |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of MUC5B mRNA deoxynivalenol results in increased expression of and results in increased secretion of MUC5B protein |
CTD |
PMID:24496642 |
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NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821
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G |
Mybbp1a |
MYB binding protein (P160) 1a |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of MYBBP1A protein |
CTD |
PMID:23352502 |
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NCBI chr11:72,332,153...72,342,596
Ensembl chr11:72,332,181...72,342,594
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G |
Myc |
myelocytomatosis oncogene |
increases expression |
ISO |
deoxynivalenol results in increased expression of MYC mRNA |
CTD |
PMID:24247028 |
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NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
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G |
Mycn |
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of MYCN protein |
CTD |
PMID:23352502 |
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NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915
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G |
Myd88 |
myeloid differentiation primary response gene 88 |
multiple interactions increases expression |
EXP |
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MYD88 protein] deoxynivalenol results in increased expression of MYD88 mRNA; deoxynivalenol results in increased expression of MYD88 protein |
CTD |
PMID:26961612 PMID:34400200 |
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NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
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G |
Myh11 |
myosin, heavy polypeptide 11, smooth muscle |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of MYH11 protein |
CTD |
PMID:23811945 |
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NCBI chr16:14,012,392...14,109,227
Ensembl chr16:14,012,399...14,109,236
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G |
Myh9 |
myosin, heavy polypeptide 9, non-muscle |
increases phosphorylation affects phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of MYH9 protein deoxynivalenol affects the phosphorylation of MYH9 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375
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G |
Myl9 |
myosin, light polypeptide 9, regulatory |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of MYL9 protein modified form Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYL9 protein modified form] |
CTD |
PMID:35817260 |
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NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578
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G |
Mylk |
myosin, light polypeptide kinase |
multiple interactions increases expression |
EXP |
Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK protein] deoxynivalenol results in increased expression of MYLK mRNA; deoxynivalenol results in increased expression of MYLK protein |
CTD |
PMID:35817260 |
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NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
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G |
Myo5c |
myosin VC |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MYO5C mRNA |
CTD |
PMID:26763390 |
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NCBI chr 9:75,139,252...75,212,733
Ensembl chr 9:75,139,302...75,212,733
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G |
Mzf1 |
myeloid zinc finger 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of MZF1 protein |
CTD |
PMID:33890134 |
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NCBI chr 7:12,777,074...12,792,244
Ensembl chr 7:12,776,230...12,788,691
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G |
Naglu |
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NAGLU mRNA |
CTD |
PMID:31863870 |
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NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498
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G |
Nampt |
nicotinamide phosphoribosyltransferase |
increases expression |
ISO |
deoxynivalenol results in increased expression of NAMPT mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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G |
Nanos1 |
nanos C2HC-type zinc finger 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NANOS1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr19:60,744,425...60,748,352
Ensembl chr19:60,744,425...60,748,352
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G |
Ncl |
nucleolin |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of NCL protein |
CTD |
PMID:23352502 |
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NCBI chr 1:86,272,441...86,287,177
Ensembl chr 1:86,272,441...86,287,122
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G |
Ndc80 |
NDC80 kinetochore complex component |
increases expression |
ISO |
deoxynivalenol results in increased expression of NDC80 mRNA |
CTD |
PMID:31863870 |
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NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852
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G |
Ndufb7 |
NADH:ubiquinone oxidoreductase subunit B7 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFB7 protein |
CTD |
PMID:33890134 |
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NCBI chr 8:84,293,387...84,298,252
Ensembl chr 8:84,293,300...84,298,255
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G |
Ndufb8 |
NADH:ubiquinone oxidoreductase subunit B8 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFB8 protein |
CTD |
PMID:33890134 |
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NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879
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G |
Ndufb9 |
NADH:ubiquinone oxidoreductase subunit B9 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFB9 protein |
CTD |
PMID:33890134 |
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NCBI chr15:58,805,650...58,811,365
Ensembl chr15:58,805,605...58,811,337
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G |
Ndufs4 |
NADH:ubiquinone oxidoreductase core subunit S4 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFS4 protein |
CTD |
PMID:33890134 |
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NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794
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G |
Ndufs5 |
NADH:ubiquinone oxidoreductase core subunit S5 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFS5 protein |
CTD |
PMID:33890134 |
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NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995
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G |
Ndufs7 |
NADH:ubiquinone oxidoreductase core subunit S7 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFS7 protein |
CTD |
PMID:33890134 |
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NCBI chr10:80,084,939...80,092,628
Ensembl chr10:80,084,955...80,092,628
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G |
Ndufv3 |
NADH:ubiquinone oxidoreductase core subunit V3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NDUFV3 protein |
CTD |
PMID:33890134 |
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NCBI chr17:31,739,089...31,750,300
Ensembl chr17:31,739,089...31,750,305
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G |
Nedd4l |
neural precursor cell expressed, developmentally down-regulated gene 4-like |
increases expression |
ISO |
deoxynivalenol results in increased expression of NEDD4L mRNA |
CTD |
PMID:31863870 |
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NCBI chr18:65,017,551...65,350,888
Ensembl chr18:65,020,776...65,350,899
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G |
Nfatc1 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 |
affects localization |
ISO EXP |
deoxynivalenol affects the localization of NFATC1 protein |
CTD |
PMID:21074547 PMID:22846391 |
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NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286
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G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
increases activity multiple interactions decreases expression increases expression |
ISO EXP |
deoxynivalenol analog results in increased activity of NFE2L2 protein; deoxynivalenol results in increased activity of NFE2L2 protein Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of NFE2L2 protein] deoxynivalenol results in decreased expression of NFE2L2 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of NFE2L2 protein] deoxynivalenol results in increased expression of NFE2L2 mRNA; deoxynivalenol results in increased expression of NFE2L2 protein |
CTD |
PMID:30244016 PMID:34400200 PMID:34677630 PMID:37419272 PMID:38040082 |
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NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
multiple interactions increases expression increases activity affects localization |
EXP ISO |
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of NFKB1 protein]; deoxynivalenol results in decreased activity of [NFKB1 protein binds to NFKB1 protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein] deoxynivalenol results in increased expression of NFKB1 mRNA deoxynivalenol affects the localization of NFKB1 protein |
CTD |
PMID:8887449 PMID:12604842 PMID:15772366 PMID:35314294 |
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NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkb2 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 |
increases expression multiple interactions |
ISO |
deoxynivalenol results in increased expression of NFKB2 mRNA deoxynivalenol inhibits the reaction [NFKB2 protein binds to CXCL8 promoter] |
CTD |
PMID:17636245 PMID:22846391 |
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NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
increases degradation multiple interactions increases phosphorylation increases expression decreases expression |
ISO EXP |
deoxynivalenol results in increased degradation of NFKBIA protein deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein] deoxynivalenol results in increased phosphorylation of NFKBIA protein deoxynivalenol results in increased expression of NFKBIA mRNA deoxynivalenol results in decreased expression of NFKBIA mRNA; deoxynivalenol results in decreased expression of NFKBIA protein lipopolysaccharide, E coli O55-B5 inhibits the reaction [deoxynivalenol results in increased degradation of NFKBIA protein] |
CTD |
PMID:8887449 PMID:18485432 PMID:23253260 PMID:24937323 PMID:26961612 PMID:34400200 More...
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NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Nfkbib |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
increases expression |
ISO |
deoxynivalenol results in increased expression of NFKBIB mRNA |
CTD |
PMID:22846391 |
|
NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
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G |
Nfya |
nuclear transcription factor-Y alpha |
increases expression |
ISO |
deoxynivalenol results in increased expression of NFYA protein |
CTD |
PMID:33890134 |
|
NCBI chr17:48,693,917...48,716,782
Ensembl chr17:48,693,913...48,716,934
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G |
Nherf1 |
NHERF family PDZ scaffold protein 1 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of NHERF1 protein |
CTD |
PMID:23811945 |
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NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
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G |
Niban3 |
niban apoptosis regulator 3 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of NIBAN3 protein |
CTD |
PMID:23811945 |
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NCBI chr 8:72,049,000...72,061,599
Ensembl chr 8:72,050,292...72,060,580
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G |
Nipbl |
NIPBL cohesin loading factor |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of NIPBL protein |
CTD |
PMID:23811945 |
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NCBI chr15:8,319,308...8,494,799
Ensembl chr15:8,320,101...8,473,947
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
EXP |
deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 protein] deoxynivalenol results in increased expression of NLRP3 mRNA; deoxynivalenol results in increased expression of NLRP3 protein |
CTD |
PMID:36309173 |
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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G |
Nod2 |
nucleotide-binding oligomerization domain containing 2 |
multiple interactions |
ISO |
[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA] |
CTD |
PMID:22003189 |
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NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
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G |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of NOLC1 mRNA |
CTD |
PMID:24247028 |
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NCBI chr19:46,064,286...46,073,982
Ensembl chr19:46,064,302...46,073,969
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G |
Nop56 |
NOP56 ribonucleoprotein |
affects phosphorylation increases phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of NOP56 protein deoxynivalenol results in increased phosphorylation of NOP56 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr 2:130,112,904...130,121,233
Ensembl chr 2:130,116,350...130,121,233
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G |
Nos2 |
nitric oxide synthase 2, inducible |
multiple interactions increases activity increases expression |
EXP ISO |
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein] deoxynivalenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] deoxynivalenol results in increased activity of NOS2 protein deoxynivalenol results in increased expression of NOS2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol results in increased ubiquitination of and results in increased degradation of NOS2 protein; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [deoxynivalenol results in increased degradation of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] |
CTD |
PMID:19857559 PMID:21748807 PMID:24937323 PMID:25766886 PMID:32416088 PMID:34673182 More...
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NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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G |
Npffr2 |
neuropeptide FF receptor 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of NPFFR2 mRNA |
CTD |
PMID:23792671 |
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NCBI chr 5:89,674,805...89,731,473
Ensembl chr 5:89,675,288...89,731,599
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G |
Npm1 |
nucleophosmin 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of NPM1 protein |
CTD |
PMID:23811945 |
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NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
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G |
Npy |
neuropeptide Y |
increases expression |
ISO |
deoxynivalenol results in increased expression of NPY mRNA |
CTD |
PMID:32738333 |
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NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
increases expression decreases expression multiple interactions |
EXP ISO |
deoxynivalenol results in increased expression of NQO1 mRNA deoxynivalenol results in decreased expression of NQO1 mRNA Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of NQO1 protein] |
CTD |
PMID:34400200 PMID:37419272 |
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
deoxynivalenol results in increased expression of NR1D1 mRNA BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of NR1D1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D1 mRNA] |
CTD |
PMID:22846391 PMID:36602574 |
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NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
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G |
Nr1d2 |
nuclear receptor subfamily 1, group D, member 2 |
multiple interactions |
EXP |
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D2 mRNA] |
CTD |
PMID:36602574 |
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NCBI chr14:4,230,549...4,265,639
Ensembl chr14:4,230,569...4,265,642
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of NR4A1 mRNA [Colforsin co-treated with deoxynivalenol] results in increased expression of NR4A1 mRNA |
CTD |
PMID:15371230 PMID:26783879 |
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NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of NR4A3 mRNA |
CTD |
PMID:26763390 |
|
NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NR5A1 mRNA |
CTD |
PMID:22982764 |
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NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554
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G |
Nrros |
negative regulator of reactive oxygen species |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of NRROS protein |
CTD |
PMID:23811945 |
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NCBI chr16:31,961,603...31,984,412
Ensembl chr16:31,961,603...31,984,412
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G |
Ntrk2 |
neurotrophic tyrosine kinase, receptor, type 2 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of NTRK2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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G |
Nucks1 |
nuclear casein kinase and cyclin-dependent kinase substrate 1 |
decreases phosphorylation affects phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of NUCKS1 protein deoxynivalenol affects the phosphorylation of NUCKS1 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr 1:131,838,196...131,864,059
Ensembl chr 1:131,838,272...131,864,059
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G |
Nudcd1 |
NudC domain containing 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of NUDCD1 mRNA |
CTD |
PMID:23792671 |
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NCBI chr15:44,238,623...44,291,703
Ensembl chr15:44,236,559...44,291,703
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G |
Nufip1 |
nuclear FMR1 interacting protein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of NUFIP1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:76,348,337...76,372,527
Ensembl chr14:76,348,331...76,374,819
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G |
Numa1 |
nuclear mitotic apparatus protein 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of NUMA1 protein |
CTD |
PMID:23352502 |
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NCBI chr 7:101,583,169...101,664,166
Ensembl chr 7:101,583,318...101,664,171
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G |
Nup155 |
nucleoporin 155 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of NUP155 protein |
CTD |
PMID:23811945 |
|
NCBI chr15:8,135,861...8,189,343
Ensembl chr15:8,138,757...8,190,731
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G |
Nup98 |
nucleoporin 98 |
affects phosphorylation increases phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of NUP98 protein deoxynivalenol results in increased phosphorylation of NUP98 protein |
CTD |
PMID:23811945 |
|
NCBI chr 7:101,768,607...101,859,359
Ensembl chr 7:101,768,605...101,859,383
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|
G |
Nusap1 |
nucleolar and spindle associated protein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of NUSAP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725
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|
G |
Oas2 |
2'-5' oligoadenylate synthetase 2 |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of OAS2 mRNA |
CTD |
PMID:17090620 |
|
NCBI chr 5:120,868,398...120,887,949
Ensembl chr 5:120,868,398...120,887,918
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|
G |
Ocln |
occludin |
affects localization decreases expression multiple interactions increases expression |
ISO EXP |
deoxynivalenol affects the localization of OCLN protein deoxynivalenol results in decreased expression of OCLN mRNA; deoxynivalenol results in decreased expression of OCLN protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA] deoxynivalenol results in increased expression of OCLN mRNA |
CTD |
PMID:20362602 PMID:24568843 PMID:34506767 PMID:35381244 PMID:35817260 |
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NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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G |
Odc1 |
ornithine decarboxylase, structural 1 |
increases activity |
EXP |
deoxynivalenol results in increased activity of ODC1 protein |
CTD |
PMID:24937323 |
|
NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
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G |
Oga |
O-GlcNAcase |
increases expression |
ISO |
deoxynivalenol results in increased expression of OGA mRNA |
CTD |
PMID:31863870 |
|
NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276
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G |
Ogg1 |
8-oxoguanine DNA-glycosylase 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of OGG1 mRNA; deoxynivalenol results in increased expression of OGG1 protein |
CTD |
PMID:24355168 |
|
NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029
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G |
Oip5 |
Opa interacting protein 5 |
increases expression |
ISO |
deoxynivalenol results in increased expression of OIP5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:119,440,013...119,448,986
Ensembl chr 2:119,439,993...119,448,950
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G |
Oser1 |
oxidative stress responsive serine rich 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of OSER1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:163,247,742...163,266,422
Ensembl chr 2:163,247,742...163,266,617
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|
G |
Ostf1 |
osteoclast stimulating factor 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of OSTF1 protein |
CTD |
PMID:23811945 |
|
NCBI chr19:18,557,728...18,609,177
Ensembl chr19:18,493,501...18,609,187
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G |
P4ha3 |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of P4HA3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:99,934,637...99,968,908
Ensembl chr 7:99,934,727...99,968,906
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G |
Palld |
palladin, cytoskeletal associated protein |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PALLD protein |
CTD |
PMID:23811945 |
|
NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724
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G |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
increases cleavage multiple interactions increases expression |
EXP ISO |
deoxynivalenol results in increased cleavage of PARP1 protein benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone affects the reaction [deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein]; deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein; GSDME protein inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein] deoxynivalenol results in increased expression of PARP1 mRNA |
CTD |
PMID:19410639 PMID:34677630 PMID:35925383 |
|
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PCK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions decreases expression |
EXP |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of PCNA protein] |
CTD |
PMID:34506767 |
|
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Pcolce |
procollagen C-endopeptidase enhancer protein |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PCOLCE mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:137,603,369...137,609,666
Ensembl chr 5:137,603,365...137,612,046
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G |
Pcyox1l |
prenylcysteine oxidase 1 like |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PCYOX1L mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:61,829,907...61,840,712
Ensembl chr18:61,829,908...61,840,706
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|
G |
Pdcd1 |
programmed cell death 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PDCD1 mRNA |
CTD |
PMID:27757495 |
|
NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
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G |
Pdcd11 |
programmed cell death 11 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PDCD11 protein |
CTD |
PMID:23352502 |
|
NCBI chr19:47,079,183...47,119,585
Ensembl chr19:47,079,207...47,120,304
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G |
Pde12 |
phosphodiesterase 12 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PDE12 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr14:26,381,113...26,390,823
Ensembl chr14:26,381,113...26,391,038
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G |
Pdlim2 |
PDZ and LIM domain 2 |
affects phosphorylation increases phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PDLIM2 protein deoxynivalenol results in increased phosphorylation of PDLIM2 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr14:70,401,667...70,415,140
Ensembl chr14:70,401,667...70,415,130
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G |
Pdlim4 |
PDZ and LIM domain 4 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PDLIM4 protein |
CTD |
PMID:23811945 |
|
NCBI chr11:53,945,754...53,959,814
Ensembl chr11:53,945,754...53,959,840
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G |
Pdss2 |
prenyl (solanesyl) diphosphate synthase, subunit 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PDSS2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:43,095,396...43,340,878
Ensembl chr10:43,097,482...43,340,878
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G |
Pea15a |
proliferation and apoptosis adaptor protein 15A |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PEA15A protein |
CTD |
PMID:23811945 |
|
NCBI chr 1:172,024,295...172,034,298
Ensembl chr 1:172,024,295...172,034,371
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G |
Per1 |
period circadian clock 1 |
multiple interactions |
EXP |
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 protein] |
CTD |
PMID:36602574 |
|
NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786
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G |
Per2 |
period circadian clock 2 |
decreases expression multiple interactions |
EXP |
deoxynivalenol results in decreased expression of PER2 mRNA; deoxynivalenol results in decreased expression of PER2 protein BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER2 protein] |
CTD |
PMID:36602574 |
|
NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046
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G |
Per3 |
period circadian clock 3 |
multiple interactions decreases expression |
EXP |
BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER3 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER3 mRNA] |
CTD |
PMID:36602574 |
|
NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122
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G |
Pgr |
progesterone receptor |
multiple interactions increases expression |
ISO |
afimoxifene inhibits the reaction [deoxynivalenol results in increased expression of PGR mRNA]; deoxynivalenol promotes the reaction [Estradiol results in increased expression of PGR mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of PGR mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA] |
CTD |
PMID:35588983 |
|
NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
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|
G |
Pgrmc1 |
progesterone receptor membrane component 1 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PGRMC1 protein |
CTD |
PMID:23811945 |
|
NCBI chr X:35,861,846...35,869,732
Ensembl chr X:35,861,859...35,869,732
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|
G |
Phax |
phosphorylated adaptor for RNA export |
increases expression |
ISO |
deoxynivalenol results in increased expression of PHAX mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:56,695,641...56,720,784
Ensembl chr18:56,695,515...56,720,784
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|
G |
Phgdh |
3-phosphoglycerate dehydrogenase |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PHGDH mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
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|
G |
Phlda1 |
pleckstrin homology like domain, family A, member 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PHLDA1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
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|
G |
Phlda3 |
pleckstrin homology like domain, family A, member 3 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PHLDA3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
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|
G |
Pi4kb |
phosphatidylinositol 4-kinase beta |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PI4KB protein |
CTD |
PMID:23811945 |
|
NCBI chr 3:94,882,042...94,914,248
Ensembl chr 3:94,882,042...94,914,154
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G |
Pik3cg |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PIK3CG protein |
CTD |
PMID:23811945 |
|
NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
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G |
Plec |
plectin |
affects phosphorylation decreases phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PLEC protein deoxynivalenol results in decreased phosphorylation of PLEC protein |
CTD |
PMID:23352502 PMID:23811945 |
|
NCBI chr15:76,055,174...76,115,578
Ensembl chr15:76,055,174...76,116,774
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G |
Plekha6 |
pleckstrin homology domain containing, family A member 6 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PLEKHA6 protein |
CTD |
PMID:23811945 |
|
NCBI chr 1:133,089,770...133,231,173
Ensembl chr 1:133,091,948...133,231,173
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G |
Plekho2 |
pleckstrin homology domain containing, family O member 2 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PLEKHO2 protein |
CTD |
PMID:23811945 |
|
NCBI chr 9:65,459,859...65,487,369
Ensembl chr 9:65,459,980...65,487,322
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G |
Plgrkt |
plasminogen receptor, C-terminal lysine transmembrane protein |
multiple interactions |
EXP |
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of PLGRKT mRNA |
CTD |
PMID:38040082 |
|
NCBI chr19:29,326,004...29,339,340
Ensembl chr19:29,325,999...29,344,790
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G |
Plin2 |
perilipin 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PLIN2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
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G |
Plpp5 |
phospholipid phosphatase 5 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PLPP5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:26,210,052...26,214,914
Ensembl chr 8:26,210,064...26,214,914
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G |
Plrg1 |
pleiotropic regulator 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PLRG1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:82,962,845...82,979,598
Ensembl chr 3:82,962,829...82,979,662
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PMAIP1 mRNA |
CTD |
PMID:22846391 PMID:24247028 |
|
NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
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G |
Pml |
promyelocytic leukemia |
decreases phosphorylation affects phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of PML protein deoxynivalenol affects the phosphorylation of PML protein |
CTD |
PMID:23352502 PMID:23811945 |
|
NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
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G |
Podnl1 |
podocan-like 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PODNL1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:84,852,552...84,869,620
Ensembl chr 8:84,852,618...84,859,156
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
multiple interactions decreases activity increases expression |
ISO EXP |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; lipopolysaccharide, E coli O55-B5 affects the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; PPARG protein affects the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; U 0126 inhibits the reaction [deoxynivalenol results in increased expression of PPARG mRNA] [Selenomethionine co-treated with deoxynivalenol] results in increased expression of PPARG mRNA deoxynivalenol results in decreased activity of PPARG protein |
CTD |
PMID:18485432 PMID:27481073 PMID:38040082 |
|
NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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G |
Ppm1d |
protein phosphatase 1D magnesium-dependent, delta isoform |
increases expression |
ISO |
deoxynivalenol results in increased expression of PPM1D mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:85,202,080...85,237,897
Ensembl chr11:85,202,070...85,237,892
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G |
Ppp2ca |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform |
increases expression |
ISO |
deoxynivalenol results in increased expression of PPP2CA mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
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G |
Ppp3cb |
protein phosphatase 3, catalytic subunit, beta isoform |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of PPP3CB mRNA Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of PPP3CB mRNA] |
CTD |
PMID:15371230 PMID:15681167 |
|
NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641
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G |
Prc1 |
protein regulator of cytokinesis 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PRC1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:79,944,224...79,966,007
Ensembl chr 7:79,944,198...79,966,007
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G |
Prelp |
proline arginine-rich end leucine-rich repeat |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PRELP mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:133,838,042...133,857,820
Ensembl chr 1:133,838,042...133,849,152
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G |
Prkar1a |
protein kinase, cAMP dependent regulatory, type I, alpha |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of PRKAR1A protein |
CTD |
PMID:23811945 |
|
NCBI chr11:109,539,849...109,560,489
Ensembl chr11:109,540,231...109,560,482
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|
G |
Prkar2a |
protein kinase, cAMP dependent regulatory, type II alpha |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of PRKAR2A protein |
CTD |
PMID:23352502 |
|
NCBI chr 9:108,569,342...108,627,643
Ensembl chr 9:108,566,513...108,627,635
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G |
Prkca |
protein kinase C, alpha |
affects localization multiple interactions |
EXP |
deoxynivalenol affects the localization of PRKCA protein Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein] |
CTD |
PMID:32416088 |
|
NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
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|
G |
Prkce |
protein kinase C, epsilon |
multiple interactions affects localization |
EXP |
Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein] |
CTD |
PMID:32416088 |
|
NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
|
|
G |
Prkcg |
protein kinase C, gamma |
multiple interactions affects localization |
EXP |
Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein] |
CTD |
PMID:32416088 |
|
NCBI chr 7:3,352,038...3,379,615
Ensembl chr 7:3,337,704...3,379,615
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|
G |
Prkd2 |
protein kinase D2 |
affects phosphorylation |
EXP |
deoxynivalenol affects the phosphorylation of PRKD2 protein |
CTD |
PMID:23811945 |
|
NCBI chr 7:16,576,827...16,604,386
Ensembl chr 7:16,576,827...16,604,389
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|
G |
Pros1 |
protein S (alpha) |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PROS1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:62,674,670...62,749,709
Ensembl chr16:62,674,670...62,749,709
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|
G |
Prpf38b |
PRP38 pre-mRNA processing factor 38 (yeast) domain containing B |
increases expression |
ISO |
deoxynivalenol results in increased expression of PRPF38B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:108,810,121...108,819,055
Ensembl chr 3:108,810,121...108,819,043
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|
G |
Prr5l |
proline rich 5 like |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PRR5L mRNA |
CTD |
PMID:26763390 |
|
NCBI chr 2:101,543,455...101,713,428
Ensembl chr 2:101,544,630...101,713,372
|
|
G |
Psat1 |
phosphoserine aminotransferase 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of PSAT1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
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|
G |
Psip1 |
PC4 and SFRS1 interacting protein 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of PSIP1 protein |
CTD |
PMID:23811945 |
|
NCBI chr 4:83,373,917...83,404,700
Ensembl chr 4:83,373,917...83,404,696
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Psmb8 |
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) |
decreases expression |
EXP |
deoxynivalenol results in decreased expression of PSMB8 mRNA |
CTD |
PMID:15371230 |
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NCBI chr17:34,417,169...34,420,428
Ensembl chr17:34,416,695...34,420,428
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Psmd12 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PSMD12 mRNA |
CTD |
PMID:31863870 |
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NCBI chr11:107,370,354...107,388,862
Ensembl chr11:107,370,310...107,395,188
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Pspc1 |
paraspeckle protein 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PSPC1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:56,959,898...57,015,775
Ensembl chr14:56,958,167...57,015,773
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Pstpip2 |
proline-serine-threonine phosphatase-interacting protein 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of PSTPIP2 mRNA |
CTD |
PMID:31863870 |
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NCBI chr18:77,882,250...77,971,462
Ensembl chr18:77,877,614...77,970,579
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Pten |
phosphatase and tensin homolog |
increases expression |
ISO |
deoxynivalenol results in increased expression of PTEN mRNA |
CTD |
PMID:22846391 |
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NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
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Ptges |
prostaglandin E synthase |
increases expression decreases expression |
EXP |
deoxynivalenol results in increased expression of PTGES mRNA deoxynivalenol results in decreased expression of PTGES mRNA |
CTD |
PMID:21873375 PMID:25549547 |
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NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875
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Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression increases stability multiple interactions |
ISO EXP |
deoxynivalenol results in increased expression of PTGS2 mRNA; deoxynivalenol results in increased expression of PTGS2 protein deoxynivalenol results in increased stability of PTGS2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased stability of PTGS2 mRNA] Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein] |
CTD |
PMID:11922776 PMID:12377986 PMID:12649040 PMID:14514436 PMID:15570035 PMID:20347963 PMID:20633634 PMID:21873375 PMID:24937323 PMID:27757495 PMID:32416088 PMID:37705238 More...
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NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Ptpn14 |
protein tyrosine phosphatase, non-receptor type 14 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of PTPN14 protein |
CTD |
PMID:23811945 |
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NCBI chr 1:189,460,417...189,608,892
Ensembl chr 1:189,460,465...189,608,892
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Ptpn22 |
protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
increases expression |
EXP |
deoxynivalenol results in increased expression of PTPN22 mRNA |
CTD |
PMID:15371230 |
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NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563
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Ptprj |
protein tyrosine phosphatase receptor type J |
increases expression |
EXP |
deoxynivalenol results in increased expression of PTPRJ mRNA |
CTD |
PMID:15371230 |
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NCBI chr 2:90,260,100...90,411,102
Ensembl chr 2:90,260,098...90,410,991
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Pycard |
PYD and CARD domain containing |
multiple interactions |
EXP |
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD mRNA; [deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD protein |
CTD |
PMID:36309173 |
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NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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Pyy |
peptide YY |
increases expression multiple interactions |
EXP |
deoxynivalenol results in increased expression of PYY protein; deoxynivalenol results in increased expression of PYY protein alternative form [Ruthenium Red co-treated with N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine] inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form] |
CTD |
PMID:22903826 PMID:26979077 |
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NCBI chr11:101,997,502...101,998,658
Ensembl chr11:101,997,502...101,998,658
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Rab18 |
RAB18, member RAS oncogene family |
increases expression |
ISO |
deoxynivalenol results in increased expression of RAB18 protein |
CTD |
PMID:33890134 |
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NCBI chr18:6,765,167...6,791,606
Ensembl chr18:6,733,905...6,794,429
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Rae1 |
ribonucleic acid export 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of RAE1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:172,841,909...172,857,532
Ensembl chr 2:172,841,910...172,857,532
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Rag1 |
recombination activating 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of RAG1 mRNA |
CTD |
PMID:38549690 |
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NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
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Rag2 |
recombination activating gene 2 |
increases expression |
ISO |
deoxynivalenol results in increased expression of RAG2 mRNA |
CTD |
PMID:38549690 |
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NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
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Raly |
hnRNP-associated with lethal yellow |
increases expression |
ISO |
deoxynivalenol results in increased expression of RALY protein |
CTD |
PMID:33890134 |
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NCBI chr 2:154,632,989...154,712,930
Ensembl chr 2:154,633,016...154,709,181
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Ramp1 |
receptor (calcitonin) activity modifying protein 1 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of RAMP1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918
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Ranbp2 |
RAN binding protein 2 |
decreases phosphorylation |
EXP |
deoxynivalenol results in decreased phosphorylation of RANBP2 protein |
CTD |
PMID:23352502 |
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NCBI chr10:58,282,674...58,329,977
Ensembl chr10:58,282,742...58,330,178
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Raver1 |
ribonucleoprotein, PTB-binding 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of RAVER1 protein |
CTD |
PMID:23352502 |
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NCBI chr 9:20,985,454...21,003,295
Ensembl chr 9:20,985,454...21,003,304
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Rbbp5 |
retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit |
increases expression |
ISO |
deoxynivalenol results in increased expression of RBBP5 mRNA |
CTD |
PMID:19438726 |
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NCBI chr 1:132,405,087...132,436,382
Ensembl chr 1:132,405,103...132,433,397
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Rbbp6 |
retinoblastoma binding protein 6, ubiquitin ligase |
increases expression |
ISO |
deoxynivalenol results in increased expression of RBBP6 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 7:122,568,980...122,601,780
Ensembl chr 7:122,564,909...122,601,780
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Rbm12 |
RNA binding motif protein 12 |
increases expression |
ISO |
deoxynivalenol results in increased expression of RBM12 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 2:155,933,876...155,953,847
Ensembl chr 2:155,933,878...155,953,898
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Rbm15 |
RNA binding motif protein 15 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of RBM15 protein |
CTD |
PMID:23352502 |
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NCBI chr 3:107,212,827...107,244,102
Ensembl chr 3:107,232,737...107,240,989
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Rbm17 |
RNA binding motif protein 17 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of RBM17 protein |
CTD |
PMID:23352502 |
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NCBI chr 2:11,590,250...11,608,061
Ensembl chr 2:11,590,248...11,608,964
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Rbm25 |
RNA binding motif protein 25 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of RBM25 protein |
CTD |
PMID:23352502 PMID:23811945 |
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NCBI chr12:83,678,990...83,729,901
Ensembl chr12:83,678,010...83,729,897
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Rbm3 |
RNA binding motif (RNP1, RRM) protein 3 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of RBM3 mRNA |
CTD |
PMID:31863870 |
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NCBI chr X:8,005,214...8,012,119
Ensembl chr X:8,005,214...8,012,119
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Rbm39 |
RNA binding motif protein 39 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of RBM39 protein |
CTD |
PMID:23811945 |
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NCBI chr 2:155,989,159...156,022,649
Ensembl chr 2:155,989,159...156,022,158
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Rcc1 |
regulator of chromosome condensation 1 |
increases phosphorylation |
EXP |
deoxynivalenol results in increased phosphorylation of RCC1 protein |
CTD |
PMID:23352502 |
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NCBI chr 4:132,059,230...132,073,061
Ensembl chr 4:132,059,230...132,080,916
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Rcor1 |
REST corepressor 1 |
increases expression |
ISO |
deoxynivalenol results in increased expression of RCOR1 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:111,005,801...111,082,336
Ensembl chr12:111,005,785...111,082,335
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Rel |
reticuloendotheliosis oncogene |
affects localization increases activity multiple interactions |
EXP |
deoxynivalenol affects the localization of REL protein deoxynivalenol results in increased activity of REL protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of REL protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein] |
CTD |
PMID:8887449 PMID:12604842 PMID:15772366 |
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NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
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Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
affects localization increases expression increases phosphorylation multiple interactions increases activity |
ISO EXP |
deoxynivalenol affects the localization of RELA protein deoxynivalenol results in increased expression of RELA mRNA; deoxynivalenol results in increased expression of RELA protein deoxynivalenol results in increased phosphorylation of RELA protein Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of RELA protein] [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; deoxynivalenol promotes the reaction [RELA protein binds to CXCL8 promoter]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein]; RELA protein promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of RELA protein] |
CTD |
PMID:16424113 PMID:17636245 PMID:18599499 PMID:20347963 PMID:22003189 PMID:22846391 PMID:24937323 PMID:34400200 More...
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NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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Relb |
avian reticuloendotheliosis viral (v-rel) oncogene related B |
increases expression |
ISO |
deoxynivalenol results in increased expression of RELB mRNA |
CTD |
PMID:22846391 |
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NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
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Rgcc |
regulator of cell cycle |
increases expression |
ISO |
deoxynivalenol results in increased expression of RGCC mRNA |
CTD |
PMID:31863870 |
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NCBI chr14:79,526,190...79,539,075
Ensembl chr14:79,526,196...79,539,085
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Rgs4 |
regulator of G-protein signaling 4 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of RGS4 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211
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Rgs5 |
regulator of G-protein signaling 5 |
decreases expression |
ISO |
deoxynivalenol results in decreased expression of RGS5 mRNA |
CTD |
PMID:31863870 |
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NCBI chr 1:169,483,070...169,523,367
Ensembl chr 1:169,483,070...169,523,382
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Rhoh |
ras homolog family member H |
increases expression |
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