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Rat Genetic Models

Gene Symbol	Gene	No. of Models	Background Strain	Strain Symbol	Aliases	Method	Availability	Origination
Defb42	defensin beta 42	2
			Slc:SD	SD-Defb42^em1Mlit		CRISPR/Cas9	Unknown	School of Life Science and Technology, Tong Ji University, Shanghai, China.
			Slc:SD	SD-Defb23^em2MlitDefb26^em2MlitDefb42^em1Mlit	Defb23/26/ 42KO rat	CRISPR/Cas9	Unknown	School of Life Science and Technology, Tong Ji University, Shanghai, China.
Muc1	mucin 1, cell surface associated	1	FHH/EurMcwi	FHH-Muc1^em1Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-18)	MCW Gene Editing Rat Resource Center
Cdh13	cadherin 13	1	SS/JrHsdMcwi	SS-Cdh13^em1Mcwi		ZFN	Cryorecovery (as of 2017-01-26)	PhysGen Knockouts
Arsb	arylsulfatase B	2
				WIAR.MPR-Arsb^abd/Ncchd	NBRP Rat No: 0651		Cryopreserved Embryo	National BioResource Project for the Rat in Japan
				MPR/Iar	MPR-Arsbabd/Iar; MPR; MPR-Arsb^abd/Iar; NBRP Rat No: 0474		Cryopreserved Embryo; Cryopreserved Sperm	National BioResource Project for the Rat in Japan
Oxtr	oxytocin receptor	1	BN/NHsdMcwi	BN-Oxtr^m1Mcwi		ENU	Unknown	PGA
Sorcs1	sortilin-related VPS10 domain containing receptor 1	2
			FHH-Chr 1^BN/Mcwi	FHH-Chr 1^BN-Sorcs1^em1Mcwi-/-	FHH-Chr 1BN-Sorcs1em1Mcwi/1Mcwi ; FHH-Chr 1^BN-Sorcs1^em1Mcwi/1Mcwi ; FHH-Chr 1BN-Sorcs1em1Mcwi-/Sorcs1em1Mcwi-	ZFN	Unknown	PhysGen Knockouts
			FHH-Chr 1^BN/Mcwi	FHH-Chr 1^BN-Sorcs1^em1Mcwi	FHH-1BN-Sorcs1em1Mcwi;FH.BN1Sorcs1em1Mcwi	ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Cyss	cystatin S	1	F344/NCrl	F344-Cyss^{Tn(sb-T2/Bart3)2.173Mcwi}		Sleeping Beauty	Unknown	PGA
Tbc1d4	TBC1 domain family, member 4	1		WI-Tbc1d4^em1Gdcz	WI-Tbc1d4^em1 ; AS160-KO		Unknown	Unit for Laboratory Animal Medicine, University of Michigan.
Gla	galactosidase, alpha	1	DA/MolTac	DA-Gla^em2Mcwi		CRISPR/Cas9	Live Animals; Cryopreserved Sperm (as of 2018-10-22)	MCW Gene Editing Rat Resource Center
Mbp	myelin basic protein	1		LE-Mbp^md	LES;Long Evans Shaker		Unknown	Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada
Plce1	phospholipase C, epsilon 1	1	F344/NCrl	F344-Plce1^{Tn(sb-T2/Bart3)2.146Mcwi}	RRRC:00380	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Ccr2	C-C motif chemokine receptor 2	1	FHH/EurMcwi	FHH-Ccr2^m1Mcwi	RRRC:00399	ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Myo7a	myosin VIIA	1		W-Myo7a^tnd/Hubr	Myo7atnd-1Hubr	ENU	Unknown	Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT Utrecht, The Netherlands.
Nr4a1	nuclear receptor subfamily 4, group A, member 1	1	FHH/EurMcwi	FHH-Nr4a1^m1Mcwi	Nr4a1-deficient rat ; Nr4a1-/-	ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Depdc5	DEP domain containing 5, GATOR1 subcomplex subunit	2
				F344-Depdc5^em1Kyo+/-		TALEN	Unknown	National Bio Resource Project Rat in Japan
				F344-Depdc5^em2Kyo+/-		TALEN	Unknown	National BioResource Project for the Rat in Japan
Crh	corticotropin releasing hormone	1		SD-Crh^em1Ionsz			Unknown	Institute of Neuroscience, Chinese Academy of Sciences
Mrs2	magnesium transporter MRS2	1		DMY/Kyo	NBRP Rat No: 0003 ; MDC-01-69		Live Animals; Cryopreserved Embryo; Cryopreserved Sperm	National BioResource Project for the Rat in Japan
Cyyr1	cysteine and tyrosine rich 1	1	F344/NCrl	F344-Cyyr1^{Tn(sb-T2/Bart3)2.328Mcwi}	RRRC:0452	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Robo1	roundabout guidance receptor 1	1	F344/NCrl	F344-Robo1^{Tn(sb-T2/Bart3)2.327Mcwi}	RRRC:00451	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Abat	4-aminobutyrate aminotransferase	1	F344/NCrl	F344-Abat^{Tn(sb-T2/Bart3)2.163Mcwi}	RRRC:0381	Sleeping Beauty	Cryopreserved Sperm (as of 2016-11-11)	PGA , Transposagen, Rat Resource & Research Center
Stk39	serine threonine kinase 39	2
			SS/JrHsdMcwi	SS-Stk39^em6Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Stk39^em5Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Mmp12	matrix metallopeptidase 12	1	HotHsd:SD	SD-Mmp12^em1Soar	Mmp12-d663(E2) ; RRRC:00770	TALEN	Cryopreserved Sperm; Cryorecovery (as of 2017-08-10)	Rat Resource and Research Center
P2rx7	purinergic receptor P2X 7	3
			SS/JrHsdMcwi	SS-P2rx7^em10Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-02-21)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-P2rx7^em13Mcwi		CRISPR/Cas9	Live Animals; Cryopreserved Sperm (as of 2018-10-10)	MCW Gene Editing Rat Resource Center
			PCK-Pkhd1^pck/CrljCrl	PCK-P2rx7^em8Mcwi		CRISPR/Cas9	Live Animals (as of 2017-02-20)	MCW Gene Editing Rat Resource Center
Ugt1a1	UDP glucuronosyltransferase family 1 member A1	2
				Gunn-Ugt1a1^j/BluHsdRrrc	RRRC:00341		Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-09-15)	Harlan , Rat Resource and Research Center
				Gunn-Ugt1a1^j/BluHsd	Gunn-Ugt1a1j		Unknown	Harlan
Sirt3	sirtuin 3	4
			SS/JrHsdMcwi	SS-Sirt3^em25Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-22)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Sirt3^em4Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			T2DN/Mcwi	T2DN-Sirt3^em35Mcwi	Strain00289	CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-22)	MCW Gene Editing Rat Resource Center
			T2DN/Mcwi	T2DN-Sirt3^em30Mcwi	Strain00290	CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Chd8	chromodomain helicase DNA binding protein 8	1	Crl:LE	LE-Chd8^em1Mcwi		CRISPR/Cas9	Unknown	Generated with support from the Simons Foundation Autism Research Initiative (SFARI); MCW Gene Editing Rat Resource Center

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