All Models

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Rat Genetic Models

Gene Symbol	Gene	No. of Models	Background Strain	Strain Symbol	Aliases	Method	Availability	Origination
Adra2a	adrenoceptor alpha 2A	2
			SS/JrHsdMcwi	SS-Adra2a^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Adra2a^em1Mcwi-/-	SS-Adra2aem1Mcwi/1Mcwi ; SS-Adra2a^em1Mcwi/1Mcwi ; SS-Adra2aem1Mcwi-/Adra2aem1Mcwi-	ZFN	Cryopreserved Sperm (as of 2019-07-26)	PhysGen Knockouts
Dmd	dystrophin	2
			Crl:SD	SD-Dmd^em1Ang	Dmd^mdx line 61 ; SD-Dmd^mdx ; Dmd^mdx	TALEN	Unknown
			WIST/Iar	W-Dmd^em1Kykn	Dystrophin mutated rat (Out of Frame-1) ; NBRP Rat No: 0779	CRISPR/Cas9	Cryopreserved Sperm (as of 2016-12-08)	National BioResource Project for the Rat in Japan
Cop1	COP1, E3 ubiquitin ligase	1	SS/JrHsdMcwi	SS-Rfwd2^em1Mcwi		CRISPR/Cas9	Cryorecovery (as of 2017-07-18)	PhysGen Knockouts
Wdr72	WD repeat domain 72	2
			SS/JrHsdMcwi	SS-Wdr72^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Wdr72^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Rorc	RAR-related orphan receptor C	2
			LEW/NCrl	LEW-Rorc^em5Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			LEW/NCrl	LEW-Rorc^em3Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Tbc1d4	TBC1 domain family, member 4	1		WI-Tbc1d4^em1Gdcz	WI-Tbc1d4^em1 ; AS160-KO		Unknown	Unit for Laboratory Animal Medicine, University of Michigan.
Agbl4	AGBL carboxypeptidase 4	1	F344/NCrl	F344-Agbl4^{Tn(sb-T2/Bart3)2.337Mcwi}	RRRC:0473	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Tp53	tumor protein p53	4
			Crl:SD	SD-Tp53^em1Sage	TGRA3990 ; SD- Tp53 tm1sage ; p53 Knockout Rat ; Tp53delta11/+	ZFN	Cryopreserved Embryo (as of 2017-05-24)	Horizon Discovery
				STOCK-Tp53^{tm1(EGFP-Pac)Qly}/Rrrc	RRRC:00485		Cryopreserved Embryo; Cryopreserved Sperm (as of 2019-02-01)	Rat Resource and Research Center
				F344-Tp53^m1Kyo	Tp53 missense ; NBRP Rat No: 0726		Cryopreserved Sperm	National BioResource Project for the Rat in Japan
			Crl:SD	SD-Tp53^em3Mcwi	SD-Trp53em3Mcwi	ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Gla	galactosidase, alpha	1	DA/MolTac	DA-Gla^em2Mcwi		CRISPR/Cas9	Live Animals; Cryopreserved Sperm (as of 2018-10-22)	MCW Gene Editing Rat Resource Center
Gpr183	G protein-coupled receptor 183	3
			SS/JrHsdMcwi	SS-Gpr183^em3Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Gpr183^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Gpr183^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Ulk4	unc-51 like kinase 4	1	SS/JrHsdMcwi	SS-Ulk4^em3Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Agtrap	angiotensin II receptor-associated protein	2
			SS/JrHsdMcwi	SS-Agtrap^em4Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Agtrap^em8Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Ttn	titin	2
				F344-Ttn^em1Sage	TTNtvA rat	ZFN	Unknown (as of 2016-11-28)	Duke-National University of Singapore, Singapore
				F344-Ttn^em2Sage	TTNtvZ rat	ZFN	Unknown (as of 2016-11-28)	Duke-National University of Singapore, Singapore
Elmod3	ELMO domain containing 3	1	F344/NCrl	F344-Elmod3^{Tn(sb-T2/Bart3)2.42Mcwi}	F344-Rbed1Tn(sb-T2/Bart3)1.42Mcwi ; F344-Rbed1^{Tn(sb-T2/Bart3)2.42Mcwi} ; RRRC:0423	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	1	SS/JrHsdMcwi	SS-Kcnj16^em1Mcwi		ZFN	Live Animals; Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Nox4	NADPH oxidase 4	5
			SS/JrHsdMcwi	SS-Nox4^em2Ncf2^em1Mcwi		ZFN	Cryopreserved Sperm; Cryorecovery (as of 2018-11-12)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Nox4^em2Mcwi-/-	SS-Nox4em2Mcwi/1Mcwi ; SS-Nox4^em2Mcwi/1Mcwi ; SS-Nox4em2Mcwi-/Nox4em2Mcwi-	ZFN	Live Animals; Cryopreserved Sperm (as of 2019-01-03)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nox4^em2Mcwi-/+	SS-Nox4em2Mcwi/2Mcwi ; SS-Nox4^em2Mcwi/2Mcwi ; SS-Nox4em2Mcwi-/Nox4em2Mcwi+	ZFN	Live Animals; Cryopreserved Sperm (as of 2019-07-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nox4^em2Mcwi		ZFN	Live Animals; Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nox4^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Pde4d	phosphodiesterase 4D	1	F344/NCrl	F344-Pde4d^{Tn(sb-T2/Bart3)2.285Mcwi}	RRRC:00436	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Rbm20	RNA binding motif protein 20	7
				(SDxF344)F1-Rbm20^m1Mlgw+/+	(SDxF344)F1-Rbm20m1Mlgw+/+;(SDxF344)F1-Rbm20m1+/Rbm20m1+		Cryopreserved Sperm	University of Wisconsin, Madison
				(SDxF344)F1xBN-Rbm20^m1Mlgw			Cryopreserved Sperm (as of 2017-01-25)	University of Wisconsin, Madison
				(SDxF344)F1xBN-Rbm20^m1Mlgw+/+	(SDxF344)F1xBN-Rbm20m1Mlgw+/+;(SDxF344)F1xBN-Rbm20m1+/Rbm20m1+		Cryopreserved Sperm	University of Wisconsin, Madison
				(SDxF344)F1-Rbm20^m1Mlgw			Cryopreserved Sperm (as of 2017-01-25)	University of Wisconsin, Madison
			SS/JrHsdMcwi	SS-Rbm20^em10Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Rbm20^em8Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Rbm20^em5Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Abcb1b	ATP-binding cassette, subfamily B (MDR/TAP), member 1B	1	SS/JrHsdMcwi	SS-Abcb1b^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-07-24)	PhysGen Knockouts
Resp18	regulated endocrine-specific protein 18	2
			SS/JrHsdMcwi	SS-Resp18^em3Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Resp18^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
F2r	coagulation factor II (thrombin) receptor	1	T2DN/Mcwi	T2DN-F2r^em1Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-10)	MCW Gene Editing Rat Resource Center
P3h3	prolyl 3-hydroxylase 3	1	F344/NCrl	F344-P3h3^{Tn(sb-T2/Bart3)2.310Mcwi}	F344-Leprel2Tn(sb-T2/Bart3)2.310Mcwi ; RRRC: 0433	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen

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