All Models

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Rat Genetic Models

Gene Symbol	Gene	No. of Models	Background Strain	Strain Symbol	Aliases	Method	Availability	Origination
Spp1	secreted phosphoprotein 1	4
			SHRSP/A3NCrl	SHRSP-Spp1^em1Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Spp1^em3Mcwi	Strain00438	CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Spp1^em4Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
			SHRSP/A3NCrl	SHRSP-Spp1^em2Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-01)	MCW Gene Editing Rat Resource Center
Serpina5	serpin family A member 5	1	SS/JrHsdMcwi	SS-Serpina5^m1Mcwi		ENU	Unknown	PGA
Apc	APC regulator of WNT signaling pathway	4
			F344/NTac	F344-Apc^Pirc/Uwm	F344-Apcm1Uwm ; Pirc ; polyposis in the rat colon (Pirc) kindred	ENU	Live Animals; Cryopreserved Sperm (as of 2018-07-16)	University of Wisconsin-Madison, Madison, Wisconsin, Rat Resource and Research Center
			ACI/SegHsd	ACI.F344-Apc^PircUwm	ACI.F344N-Apc^Pirc	ENU	Cryopreserved Sperm (as of 2017-02-06)	University of Wisconsin-Madison, Madison, Wisconsin, Rat Resource and Research Center
			BN/Crl	BN.F344-Apc^Pirc		ENU	Cryopreserved Sperm (as of 2017-02-10)	Rat Resource and Research Center
				F344-Apc^m1Kyo	F344-APCKyo1588/Kyo; F344-APC^Kyo1588/Kyo; F344-APCKyo1588/Kyo; F344-Apcm1Kyo; NBRP Rat No: 0443 ; Apc delta 2523, Kyoto Apc Delta rat ; KAD rats	ENU	Live Animals; Cryopreserved Sperm (as of 2017-03-14)	National BioResource Project for the Rat in Japan
Spta1	spectrin, alpha, erythrocytic 1	1	F344/NCrl	F344-Spta1^{Tn(sb-T2/Bart3)2.315Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Cyp7b1	cytochrome P450 family 7 subfamily B member 1	1	F344/NCrl	F344-Cyp7b1^{Tn(sb-T2/Bart3)2.306Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Tsc2	TSC complex subunit 2	1		LETsc2^Eker/Hin	Eker rat ; Eker-Tsc2/Hin		Unknown	Department of Experimental Pathology, Cancer Institute, Toshima-ku, Tokyo Japan
Cyp2j4	cytochrome P450, family 2, subfamily j, polypeptide 4	1	WKY/NCrl	WKY-Cyp2j4^em1Sage/Tja	WKY-Cyp2j4-KO ; Cyp2j4-/-	ZFN	Unknown
Scn2a	sodium voltage-gated channel alpha subunit 2	1	Crl:LE	LE-Scn2a^em1Mcwi		CRISPR/Cas9	Live Animals (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
Agtr1a	angiotensin II receptor, type 1a	2
			SS/JrHsdMcwi	SS-Agtr1a^em5Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Agtr1a^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2021-11-03)	PhysGen Knockouts
Ets1	ETS proto-oncogene 1, transcription factor	2
				SS-Ets1^em1Mcwi-/+	SS-Ets1em1Mcwi/2Mcwi ; SS-Ets1^em1Mcwi/2Mcwi ; SS-Ets1em1Mcwi-/Est1em1Mcwi+		Cryopreserved Sperm (as of 2018-09-05)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Ets1^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Myo1d	myosin ID	1	F344/NCrl	F344-Myo1d^{Tn(sb-T2/Bart3)2.334Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Lzic	leucine zipper and CTNNBIP1 domain containing	1	F344/NCrl	F344-Lzic^{Tn(sb-T2/Bart3)2.309Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Ahr	aryl hydrocarbon receptor	4
			Hsd:SD	SD-Ahr^em2Sage		ZFN	Unknown
			Crl:SD	SD-Nr1i2^em1Sage Nr1i3^em1Sage Ahr^em1Sage	TGRS9030 ; NR1i2/NR1i3/AHR ; SD-NR1i2/NR1i3/AHR tm1sage	ZFN	Cryopreserved Embryo (as of 2017-05-10)	Horizon Discovery
			Crl:SD	SD-Ahr^em1Sage	TGRS8890 ; SD- Ahr tm1sage ; AHR Knockout Rat	ZFN	Live Animals (as of 2017-05-10)	Horizon Discovery
			HotHsd:SD	SD-Ahr^em1Soar	Ahr null	CRISPR/Cas9	Cryopreserved Sperm; Cryorecovery (as of 2019-01-21)	Rat Resource and Research Center
Cyyr1	cysteine and tyrosine rich 1	1	F344/NCrl	F344-Cyyr1^{Tn(sb-T2/Bart3)2.328Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Nox4	NADPH oxidase 4	5
			SS/JrHsdMcwi	SS-Nox4^em2Ncf2^em1Mcwi		ZFN	Cryopreserved Sperm; Cryorecovery (as of 2018-11-12)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Nox4^em2Mcwi-/-	SS-Nox4em2Mcwi/1Mcwi ; SS-Nox4^em2Mcwi/1Mcwi ; SS-Nox4em2Mcwi-/Nox4em2Mcwi-	ZFN	Live Animals; Cryopreserved Sperm (as of 2019-01-03)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nox4^em2Mcwi-/+	SS-Nox4em2Mcwi/2Mcwi ; SS-Nox4^em2Mcwi/2Mcwi ; SS-Nox4em2Mcwi-/Nox4em2Mcwi+	ZFN	Live Animals; Cryopreserved Sperm (as of 2019-07-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nox4^em2Mcwi		ZFN	Live Animals; Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nox4^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Aspa	aspartoacylase	3
				F344 -Aspa^em34Kyo Hcn1^em1Kyo		Other	Unknown	Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan
				F344-Aspa^em31Kyo	Aspa KO (Line #31) ; NBRP Rat No: 0805	TALEN	Cryopreserved Sperm (as of 2016-11-16)	National BioResource Project for the Rat in Japan
				F344-Aspa^em34Kyo	NBRP Rat No: 0806 ; Aspa KO (Line #34)	TALEN	Cryopreserved Sperm (as of 2016-11-16)	National BioResource Project for the Rat in Japan
Ano3	anoctamin 3	1	F344/NCrl	F344-Ano3^{Tn(sb-T2/Bart3)2.307Mcwi}	F344-Tmem16cTn(sb-T2/Bart3)2.307Mcwi ; F344-Tmem16c^{Tn(sb-T2/Bart3)2.307Mcwi}	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Nsun4	NOP2/Sun RNA methyltransferase 4	1	F344/NCrl	F344-Nsun4^{Tn(sb-T2/Bart3)2.286Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Ube3a	ubiquitin protein ligase E3A	1	Hsd:SD	SD-Ube3a^em1Jue		CRISPR/Cas9	Unknown
Tgfbr2	transforming growth factor, beta receptor 2	1	FHH/EurMcwi	FHH-Tgfbr2^m2Mcwi		ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Kcna1	potassium voltage-gated channel subfamily A member 1	1		F344-Kcna1^Adms/Kyo	F344-Ker/Kyo;NBRP Rat No: 0458 ; F344-Ker/Kyo ; Kyoto Epileptic Rat ; Boo ; F344-Adms/Kyo		Live Animals; Cryopreserved Sperm (as of 2017-05-04)	National BioResource Project for the Rat in Japan

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