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Rat Genetic Models

Gene Symbol	Gene	No. of Models	Background Strain	Strain Symbol	Aliases	Method	Availability	Origination
Nlrp12	NLR family, pyrin domain containing 12	1	SS/JrHsdMcwi	SS-Nlrp12^em1Mcwi		CRISPR/Cas9	Live Animals; Cryopreserved Sperm (as of 2018-11-12)	MCW Gene Editing Rat Resource Center
Slc6a12	solute carrier family 6 member 12	1	SS/JrHsdMcwi	SS-Slc6a12^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Tsc2	TSC complex subunit 2	1		LETsc2^Eker/Hin	Eker rat ; Eker-Tsc2/Hin		Unknown	Department of Experimental Pathology, Cancer Institute, Toshima-ku, Tokyo Japan
Dnah11	dynein, axonemal, heavy chain 11	1	F344/NCrl	F344-Dnah11^{Tn(sb-T2/Bart3)2.293Mcwi}	RRRC:0429	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Nlrp3	NLR family, pyrin domain containing 3	2
			SS/JrHsdMcwi	SS-Nlrp3^em1Mcwi		CRISPR/Cas9	Unknown	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Nlrp3^em2Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-09-28)	MCW Gene Editing Rat Resource Center
Bsn	bassoon (presynaptic cytomatrix protein)	1		SD-Bsn^em1Ionsz			Unknown	Institute of Neuroscience, Chinese Academy of Sciences
Cyss	cystatin S	1	F344/NCrl	F344-Cyss^{Tn(sb-T2/Bart3)2.173Mcwi}		Sleeping Beauty	Unknown	PGA
Park7	Parkinsonism associated deglycase	2
			Crl:LE	LE-Park7^em1Sage-/-	;LE-Park7em1Sage-/Park7em1Sage- ; TGRL4830 ; LEH- Park7 tm1sage ; Park7 (DJ-1) Knockout Rat	ZFN	Live Animals (as of 2017-05-08)	Horizon Discovery
				LE-Park7^em1Sage			Unknown	Sigma Advanced Genetic Engineering Labs
Intu	inturned planar cell polarity protein	1	F344/NCrl	F344-Intu^{Tn(sb-T2/Bart3)2.324Mcwi}	RRRC:0441	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Trpc6	transient receptor potential cation channel, subfamily C, member 6	3
			SS/JrHsdMcwi	SS-Trpc6^em4Mcwi	SS-Trpc6^{em1(P112Q)Mcwi}	CRISPR/Cas9	Live Animals (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Trpc6^em3Mcwi		CRISPR/Cas9	Cryorecovery (as of 2017-07-18)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Trpc6^em1Mcwi		CRISPR/Cas9	Live Animals (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Cacna1g	calcium voltage-gated channel subunit alpha1 G	1	SS/JrHsdMcwi	SS-Cacna1g^m1Mcwi		ENU	Unknown	PGA
Vnn1	vanin 1	2
			SS/HsdMcwiCrl	SS-Vnn1^em2Mcwi	SS-Vnn1tm1(N131S)Mcwi ; SS-Vnn1em1(N131S)Mcwi	CRISPR/Cas9	Live Animals; Cryopreserved Sperm (as of 2018-10-10)	MCW Gene Editing Rat Resource Center
			SS/HsdMcwiCrl	SS-Vnn1^em1Mcwi		CRISPR/Cas9	Live Animals; Cryopreserved Sperm (as of 2018-10-10)	MCW Gene Editing Rat Resource Center
Atm	ATM serine/threonine kinase	2
			F344/NSlc	F344-Atm^m1Kyo	NBRP No.0627	ENU	Live Animals; Cryopreserved Sperm (as of 2017-04-18)	National BioResource Project for the Rat in Japan
			F344/Stm	F344-Atm^em1Kyo	NBRP No.0649	ZFN	Live Animals; Cryopreserved Sperm (as of 2017-04-18)	National BioResource Project for the Rat in Japan
Oxtr	oxytocin receptor	1	BN/NHsdMcwi	BN-Oxtr^m1Mcwi		ENU	Unknown	PGA
Apoe	apolipoprotein E	2
				SD-Apoe^em1Sage	SD- ApoE tm1sage ; TGRA3710	ZFN	Live Animals (as of 2017-05-01)	Horizon Discovery
			SS/JrHsdMcwi	SS-Apoe^em9Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Ccdc85c	coiled-coil domain containing 85C	1	F344/Stm	F344-Ccdc85c^em1Kyo	F344 Ccdc85c KO ; NBRP Rat No: 0824	TALEN	Cryopreserved Sperm (as of 2016-11-18)	National BioResource Project for the Rat in Japan
Kcna1	potassium voltage-gated channel subfamily A member 1	1		F344-Kcna1^Adms/Kyo	F344-Ker/Kyo;NBRP Rat No: 0458 ; F344-Ker/Kyo ; Kyoto Epileptic Rat ; Boo ; F344-Adms/Kyo		Live Animals; Cryopreserved Sperm (as of 2017-05-04)	National BioResource Project for the Rat in Japan
Lrrc4c	leucine rich repeat containing 4C	1	F344/NCrl	F344-Lrrc4c^{Tn(sb-T2/Bart3)2.254Mcwi}	RRRC:00359	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Anks6	ankyrin repeat and sterile alpha motif domain containing 6	2
				SPRD-Anks6^PKD/Rrrc	RRRC:0046 ; SPRD-Pkdr1/Rrrc ; SPRD-Pkdr1/Rrrc ; SPRD-Anks6/Rrrc		Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-03-07)	Rat Resource and Research Center
				SPRD-Anks6^PKD/Fsn	SPRD-Anks6m1Fsn ; Cy rat ; Han:SPRD-Cy ; NBRP Rat No: 0684		Cryopreserved Sperm (as of 2018-04-20)	National BioResource Project for the Rat in Japan
Nos3	nitric oxide synthase 3	3
			SS/JrHsdMcwi	SS-Nos3^em13Mcwi		ZFN	Live Animals; Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nos3^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Nos3^em8Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
F10	coagulation factor X	2
			FHH/EurMcwi	FHH-F10^m2Mcwi	RRRC:00412	ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
			FHH/EurMcwi	FHH-F10^m1Mcwi	RRRC:00401	ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Mbp	myelin basic protein	1		LE-Mbp^md	LES;Long Evans Shaker		Unknown	Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada
Mstn	myostatin	4
			SS/JrHsdMcwi	SS-Mstn^em1Mcwi-/-	SS-Mstnem1Mcwi/1Mcwi ; SS-Mstn^em1Mcwi/1Mcwi ; SS-Mstnem1Mcwi-/Mstnem1Mcwi-	ZFN	Cryopreserved Sperm (as of 2019-07-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Mstn^em3Mcwi-/-	SS-Mstnem3Mcwi/1Mcwi ; SS-Mstn^em3Mcwi/1Mcwi ; SS-Mstnem3Mcwi-/Mstnem3Mcwi-	ZFN	Cryopreserved Sperm (as of 2019-07-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Mstn^em3Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Mstn^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Gnb3	G protein subunit beta 3	1	SS/JrHsdMcwi	SS-Gnb3^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Defb42	defensin beta 42	2
			Slc:SD	SD-Defb42^em1Mlit		CRISPR/Cas9	Unknown	School of Life Science and Technology, Tong Ji University, Shanghai, China.
			Slc:SD	SD-Defb23^em2MlitDefb26^em2MlitDefb42^em1Mlit	Defb23/26/ 42KO rat	CRISPR/Cas9	Unknown	School of Life Science and Technology, Tong Ji University, Shanghai, China.

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