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Rat Genetic Models

Gene Symbol	Gene	No. of Models	Background Strain	Strain Symbol	Aliases	Method	Availability	Origination
Rasgrp3	RAS guanyl releasing protein 3	2
			SS/JrHsdMcwi	SS-Rasgrp3^em3Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Rasgrp3^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Cadm2	cell adhesion molecule 2	1	F344/NCrl	F344-Cadm2^{Tn(sb-T2/Bart3)2.180Mcwi}	F344-Igsf4d_predicted^{Tn(sb-T2/Bart3)2.180Mcwi} ; F344-Igsf4d^{Tn(sb-T2/Bart3)2.180Mcwi} ; F344-Igsf4d_predictedTn(sb-T2/Bart3)2.180Mcwi	Sleeping Beauty	Unknown	PGA
Il15	interleukin 15	1	HotHsd:SD	SD-Il15^em1Soar	Il15-d7(E2) ; RRRC:00769		Unknown	Rat Resource and Research Center
Lrrc4c	leucine rich repeat containing 4C	1	F344/NCrl	F344-Lrrc4c^{Tn(sb-T2/Bart3)2.254Mcwi}	RRRC:00359	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
F10	coagulation factor X	2
			FHH/EurMcwi	FHH-F10^m2Mcwi	RRRC:00412	ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
			FHH/EurMcwi	FHH-F10^m1Mcwi	RRRC:00401	ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Cd40	CD40 molecule	1	SS/JrHsd	SS-Cd40^em1Uthal-/-	RRRC:00840 ; Cd40mutant	ZFN	Unknown	Rat Resource and Research Center
Ndufc2	NADH:ubiquinone oxidoreductase subunit C2	3
			SHR/NCrl	SHR-Ndufc2^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SHR/NCrl	SHR-Ndufc2^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
				SHR-Ndufc2^em1Mcwi-/+	SHR-Ndufc2em1Mcwi-/Ndufc2em1Mcwi+		Unknown	PhysGen Knockouts
Aspa	aspartoacylase	3
				F344 -Aspa^em34Kyo Hcn1^em1Kyo		Other	Unknown	Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan
				F344-Aspa^em31Kyo	Aspa KO (Line #31) ; NBRP Rat No: 0805	TALEN	Cryopreserved Sperm (as of 2016-11-16)	National BioResource Project for the Rat in Japan
				F344-Aspa^em34Kyo	NBRP Rat No: 0806 ; Aspa KO (Line #34)	TALEN	Cryopreserved Sperm (as of 2016-11-16)	National BioResource Project for the Rat in Japan
Arhgef11	Rho guanine nucleotide exchange factor 11	2
			SS/JrHsdMcwi	SS-Arhgef11^em5Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-22)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Arhgef11^em4Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
Shc1	SHC adaptor protein 1	4
			SS/JrHsdMcwi	SS-Shc1^em3Mcwi	SS-p66Shcem3Mcwi	ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Shc1^em4Mcwi	SS-p66Shcem4Mcwi	ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Shc1^em1Mcwi	SS-p66Shcem1Mcwi	ZFN	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Shc1^em5Mcwi	SS-p66Shctm1(S36A)Mcwi ; SS-Shc1^{em1(S36A)Mcwi}	ZFN	Live Animals (as of 2017-01-25)	MCW Gene Editing Rat Resource Center
Trpv4	transient receptor potential cation channel, subfamily V, member 4	2
			WKY/NCrl	WKY-Trpv4^em5Mcwi	SS-Trpv4em5Mcwi	CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center
			WKY/NCrl	WKY-Trpv4^em4Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
Xdh	xanthine dehydrogenase	2
			SS/JrHsdMcwi	SS-Xdh^em1Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
			SS/JrHsdMcwi	SS-Xdh^em2Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
Cd59	CD59 molecule	1		SD-Cd59^em1Ask-/-		CRISPR/Cas9	Unknown	Cardiovascular Research Institute,University of California San Francisco, CA 94143-0521 USA
Erbb4	erb-b2 receptor tyrosine kinase 4	1	F344/NCrl	F344-Erbb4^{Tn(sb-T2/Bart3)2.208Mcwi}	RRRC:0383	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Fyn	FYN proto-oncogene, Src family tyrosine kinase	1	SS/JrHsdMcwi	SS-Fyn^em6Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Avp	arginine vasopressin	5
				BRAT-Avp^di/BluHsd	BB ; HsdBlu:BRAT-Avpdi		Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-06-21)
				BRAT-Avp^di/BluHsd	BB ; HsdBlu:BRAT-Avpdi		Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-06-21)
				BRAT-Avp^di/BluHsdRrrc	RRRC:00445 ; RrrcHsdBlu:BRAT-Avpdi ; HsdBlu:BRAT-Avp^diRrrc		Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-06-21)	Rat Resource and Research Center
				BRAT-Avp^di/BluHsd	BB ; HsdBlu:BRAT-Avpdi		Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-06-21)
				BRAT-Avp^di/BluHsd	BB ; HsdBlu:BRAT-Avpdi		Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-06-21)
Mc4r	melanocortin 4 receptor	1	Crl:WI	WI-Mc4r^m1Hubr	Mc4r^1Hubr ; W-Mc4r^m1Hubr	ENU	Unknown	Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT Utrecht, The Netherlands. Hera Biolabs, Taconic.
Ednrb	endothelin receptor type B	6
				Sl	spotting lethal		Unknown	Institute of Animal Reproduction, Omiya, Japan
				LE/Hkv.AR-Ednrb^sl	LEH/Hkv-Ednrb^sl ; LEH/Hkv-Ednrbsl ; LEH.AR-Ednrbsl/Hkv ; NBRP Rat No: 0802 ; LEH.AR-Ednrb^sl/Hkv		Cryopreserved Embryo (as of 2016-11-15)	Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan, National BioResource Project for the Rat in Japan
				F344.AR-Ednrb^sl/Hkv	F344-Ednrbsl ; F344-Ednrb^sl ; F344-EdnrbslHkv ; NBRP Rat No: 0801		Cryopreserved Embryo (as of 2016-10-28)	Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan, National BioResource Project for the Rat in Japan
				AR-Ednrb^sl/Hkv	AGH/Hkv-Ednrb^sl ; AGH/Hkv-Ednrbsl ; AGH-Ednrbsl		Unknown	Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan
				LE.AR-Ednrb^sl/Okkm	LE.AR-Ednrbsl/Okkm;LE.AR-sl;NBRP Rat No: 0557		Cryopreserved Embryo (as of 2017-03-28)	National BioResource Project for the Rat in Japan
				AR-Ednrb^sl/Okkm	AR-Ednrbsl/Okkm;NBRP Rat No: 0556;AR;AR rats		Cryopreserved Embryo (as of 2016-10-31)	National BioResource Project for the Rat in Japan
Dnmt1	DNA methyltransferase 1	1		SD-Dnmt1^{tm1(Myh6-cre)Cqin}	Dnmt1-KO	Other	Unknown	Beijing Engineering Research Center for Experimental Animal Models of Human Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College (ZLF18003), Beijing, China
Tsc2	TSC complex subunit 2	1		LETsc2^Eker/Hin	Eker rat ; Eker-Tsc2/Hin		Unknown	Department of Experimental Pathology, Cancer Institute, Toshima-ku, Tokyo Japan
Glp1r	glucagon-like peptide 1 receptor	3
			LEW/NCrl	Lew-Glp1r^em1Mcwi		CRISPR/Cas9	Unknown	MCW Gene Editing Rat Resource Center
			LEW/NCrl	Lew-Glp1r^em2Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center
			LEW/NCrl	Lew-Glp1r^em3Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center

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