This is a hypertensive strain which has many features of salt-sensitive hypertension in humans. These are salt-sensitive, hyperlipidemic, insulin-resistant and have a low-renin form of hypertension. Renal, cardiac and vascular end organ damage is observed after severe hypertension. (REF RGD ID: 727992)
Female-specific linkage analysis in 99 female F2 derived from male SS/JrHsdMcwi and female BN/NHsdMcwi where 126 QTL were identified.
Other Phenotypes...increased blood pressure (REF RGD ID: 628478), increased heart rate (REF RGD ID: 727992), increased kidney weight (REF RGD ID: 727992)
These are resistant to hypertension with a high salt diet. Generally used as a control strain for SS rats (REF RGD ID:61053)
Other Phenotypes...decreased blood pressure (REF RGD ID: 61040), decreased body weight (REF RGD ID: 61040),
In the presence of dietary salt as an environmental factor develops hypertension with age. This parental strain is used in 157 out of 420 QTL (REF RGD ID:629622)
Other Phenotypes...increased blood pressure (REF RGD ID: 61040), enlarged heart (REF RGD ID: 619631), increased body weight (REF RGD ID: 619631)
Female-specific linkage analysis in 99 female F2 derived from SS/JrHsdMcwi and BN/NHsdMcwi where 126 QTL were identified.(REF RGD ID: 727992)
Model for Myocardial Ischemia
Other Phenotypes...decreased renin activity (REF RGD ID: 727992)
These have increased body weight, hyperlipidemia and high blood pressure which are common features to the human metabolic syndrome.(REF RGD ID:1302893). Heart rate is similar to LN/Mav at 5 wks of age. (REF RGD ID:1580397)
