Gene: ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2) Homo sapiens
Symbol: ARFGEF2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Description: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); BIG2; brefeldin A-inhibited GEP 2; brefeldin A-inhibited guanine nucleotide-exchange protein 2; dJ1164I10.1; FLJ23723; OTTHUMP00000031231; PVNH2
Orthologs:
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382048,921,721 - 49,036,693 (+)NCBIGRCh38hg38GRCh38
GRCh372047,538,250 - 47,653,230 (+)NCBIGRCh37hg19GRCh37
Build 362046,971,682 - 47,086,637 (+)NCBINCBI36hg18NCBI36
Build 342046,971,833 - 47,083,645NCBI
Celera2044,242,891 - 44,357,843 (+)NCBI
Cytogenetic Map20q13.13NCBImapview
HuRef2044,289,793 - 44,403,088 (+)NCBI
CHM1_12047,442,300 - 47,557,463 (+)NCBI
Model


Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARFGEF2
Entrez Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736641
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2016-07-05
Status: ACTIVE