Gene: ARFGEF2 (ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)) Homo sapiens
Symbol: ARFGEF2
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Description: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BIG2; brefeldin A-inhibited GEP 2; brefeldin A-inhibited guanine nucleotide-exchange protein 2; dJ1164I10.1; FLJ23723; OTTHUMP00000031231; PVNH2
Orthologs:
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Genome Assembly GRCh382048,921,713 - 49,036,693+NCBI
Human Alternate Assembly CHM1_12047,442,300 - 47,557,463+NCBI
Human Genome Assembly HuRef2044,289,793 - 44,403,088+NCBI
Human Genome Assembly GRCh372047,538,250 - 47,653,230+NCBI
Human Genome Assembly Build 362046,971,682 - 47,086,637+NCBI
Human Cytogenetic Map20q13.13 NCBI
Human Genome Assembly2046,971,833 - 47,083,645 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARFGEF2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736641
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2014-07-23
Status: ACTIVE