Gene: SLC18A3 (solute carrier family 18 member A3) Homo sapiens
Symbol: SLC18A3
Name: solute carrier family 18 member A3
Description: This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CMS21; MGC12716; OTTHUMP00000019582; solute carrier family 18 (vesicular acetylcholine transporter), member 3; solute carrier family 18 (vesicular acetylcholine), member 3; solute carrier family 18 member 3; solute carrier family 18, member 3; VACHT; vesicular acetylcholine transporter
Mus musculus (house mouse) : Slc18a3 (solute carrier family 18 (vesicular monoamine), member 3)  MGI
Rattus norvegicus (Norway rat) : Slc18a3 (solute carrier family 18 member A3)
Chinchilla lanigera (long-tailed chinchilla) : Slc18a3 (solute carrier family 18 member A3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC18A3 (solute carrier family 18 member A3)
Canis lupus familiaris (dog) : SLC18A3 (solute carrier family 18 member A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc18a3 (solute carrier family 18 member A3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381049,610,301 - 49,612,720 (+)NCBIGRCh38hg38GRCh38
GRCh371050,818,347 - 50,820,766 (+)NCBIGRCh37hg19GRCh37
Build 361050,488,353 - 50,490,772 (+)NCBINCBI36hg18NCBI36
Build 341050,488,352 - 50,490,771NCBI
Celera1044,404,433 - 44,406,852 (+)NCBI
Cytogenetic Map10q11.23NCBImapview
HuRef1045,083,115 - 45,085,534 (+)NCBI
CHM1_11051,100,431 - 51,102,850 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC18A3
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 732691
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2017-07-11
Status: ACTIVE