Gene: Itm2b (integral membrane protein 2B) Rattus norvegicus
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Symbol: Itm2b
Name: integral membrane protein 2B
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); ATP binding (ortholog); INVOLVED IN extrinsic apoptotic signaling pathway in absence of ligand (ortholog); negative regulation of amyloid precursor protein biosynthetic process (ortholog); ASSOCIATED WITH Dementia, Familial British (ortholog); Dementia, Familial Danish (ortholog); Hypertension (ortholog); FOUND IN extracellular exosome (ortholog); extracellular space (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bri; imBRI2; immature BRI2; MGC94644; transmembrane protein BRI
Orthologs:
Homo sapiens (human) : ITM2B (integral membrane protein 2B)  HGNC  AGR
Mus musculus (house mouse) : Itm2b (integral membrane protein 2B)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Itm2b (integral membrane protein 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : ITM2B (integral membrane protein 2B)
Canis lupus familiaris (dog) : ITM2B (integral membrane protein 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itm2b (integral membrane protein 2B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01555,254,703 - 55,277,713 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01558,977,916 - 59,000,926 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41554,005,134 - 54,028,036 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11554,020,916 - 54,021,022 (-)NCBI
Celera1548,194,879 - 48,217,785 (-)NCBI
Cytogenetic Map15q11NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itm2b
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 620727
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE