Gene: Nos3 (nitric oxide synthase 3, endothelial cell)  Rattus norvegicus

Symbol: Nos3
Name: nitric oxide synthase 3, endothelial cell
Description: ENCODES a protein that exhibits Hsp90 protein binding; nitric-oxide synthase activity; actin monomer binding (ortholog); INVOLVED IN aging; cellular response to heat; cellular response to mechanical stimulus; PARTICIPATES IN eicosanoid signaling pathway; vascular endothelial growth factor signaling pathway; arginine and proline metabolic pathway; ASSOCIATED WITH Alzheimer Disease; Arteriovenous Fistula; Brain Ischemia; FOUND IN apical part of cell; cytoplasm; Golgi apparatus; INTERACTS WITH (R)-carnitine; 1,3-dinitrobenzene; 11-deoxycorticosterone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cNOS; constitutive NOS; EC-NOS; endothelial nitric oxide synthase 3; endothelial NOS; eNos; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS type III; NOSIII
Orthologs: Homo sapiens : NOS3 (nitric oxide synthase 3 (endothelial cell))  HGNC
Mus musculus : Nos3 (nitric oxide synthase 3, endothelial cell)  MGI
Allele / Splice: Nos3em2Mcwi   Nos3em8Mcwi   Nos3em13Mcwi  
Is Marker For: Strains:   DA.WF-(D4Mit11-Nos3)/Kop  
QTLs:   Tcas3   BW384_H  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map4q11 NCBI
RGSC Genome Assembly v5.047,333,452 - 7,353,763-NCBI
RGSC Genome Assembly v3.446,158,847 - 6,179,441-NCBI
Rat Celera Assembly46,408,408 - 6,428,650-NCBI
Genome Assembly 3.146,158,846 - 6,179,441-NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)
Related Rat Strains

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nos3
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RGD Object Information
RGD ID: 3186
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE