Gene: Egfr (epidermal growth factor receptor) Rattus norvegicus
Symbol: Egfr
Name: epidermal growth factor receptor
Description: ENCODES a protein that exhibits epidermal growth factor binding; epidermal growth factor-activated receptor activity; glycoprotein binding; INVOLVED IN activation of MAPKK activity; alkanesulfonate metabolic process; astrocyte activation; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; altered epidermal growth factor/neuregulin signaling pathway; E-cadherin signaling pathway; ASSOCIATED WITH abnormal estrous cycle; heart left ventricle hypertrophy; renal fibrosis; ASSOCIATED WITH Asthma; Cardiomyopathy, Dilated; Diabetes Mellitus, Experimental; FOUND IN apical plasma membrane; basolateral plasma membrane; cell surface; INTERACTS WITH (+)-pilocarpine; (R)-mevalonic acid; (R)-noradrenaline
Type: protein-coding
Also known as: avian erythroblastic leukemia viral (v-erbB) oncogene homolog; Egfr-related peptide; Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); Epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ErbB-1; ERBB1; Errp
Latest Assembly: RGSC Genome Assembly v3.4
Rat Cytogenetic Map14q22 NCBI
RGSC Genome Assembly v5.014100,438,989 - 100,617,315-NCBI
RGSC Genome Assembly v3.41497,617,358 - 97,788,211+NCBI
Rat Celera Assembly1490,225,928 - 90,392,779+NCBI
Genome Assembly 3.11497,636,502 - 97,807,356+NCBI
RH 3.414674.9 RGD

Launch Genome Browser (GBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Egfr
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2543
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-07-22
Status: ACTIVE