Gene: Ctsb (cathepsin B) Mus musculus
Symbol: Ctsb
Name: cathepsin B
Description: ENCODES a protein that exhibits collagen binding (ortholog); cysteine-type endopeptidase activity (ortholog); cysteine-type peptidase activity (ortholog); INVOLVED IN decidualization; collagen catabolic process (ortholog); negative regulation of cell death (ortholog); PARTICIPATES IN antigen processing and presentation pathway; ASSOCIATED WITH abnormal hippocampus pyramidal cell layer; abnormal motor coordination/ balance; abnormal neuron apoptosis; ASSOCIATED WITH Atherosclerosis; Colitis; Diabetes Mellitus, Type 1; FOUND IN lysosome; mitochondrion; apical plasma membrane (ortholog); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cathepsin B1; CB
Homo sapiens : CTSB (cathepsin B)  HGNC
Rattus norvegicus : Ctsb (cathepsin B)
more info ...
Related Pseudogenes: Gm14032  
Latest Assembly: Mouse Genome Assembly Build 37
Mouse Genome Assembly GRCm381463,122,462 - 63,145,923+NCBI
Mouse cM Map1433.24 NCBI
Mouse Celera Assembly1460,885,227 - 60,908,695+NCBI
Mouse Genome Assembly Build 371463,741,302 - 63,764,758+NCBI
Mouse Genome Assembly Build 36.11462,076,575 - 62,100,031+NCBI
Mouse Cytogenetic Map14 D1 NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ctsb
Entrez Gene
Ensembl Gene
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MGI Report
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Vista + UCSC

RGD Object Information
RGD ID: 1558619
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2015-07-07
Status: ACTIVE