Gene: NME2 (NME/NM23 nucleoside diphosphate kinase 2) Homo sapiens
Symbol: NME2
Name: NME/NM23 nucleoside diphosphate kinase 2
Description: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; histidine protein kinase NDKB; MGC111212; MGC2212; NDK B; NDKB; NDP kinase B; NDPK-B; NDPKB; NM23-H2; NM23B; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; nucleoside diphosphate kinase B; nucleotide diphosphate kinase B; OTTHUMP00000174727; OTTHUMP00000174728; OTTHUMP00000174774; OTTHUMP00000174775; OTTHUMP00000174776; PUF
Related Pseudogenes: NME2P1  
Latest Assembly: Human Genome Assembly GRCh37
Human Genome Assembly GRCh381751,165,435 - 51,171,744+NCBI
Human Alternate Assembly CHM1_11749,307,431 - 49,313,740+NCBI
Human Genome Assembly HuRef1744,612,062 - 44,618,375+NCBI
Human Genome Assembly GRCh371749,242,796 - 49,249,105+NCBI
Human Celera Assembly1745,704,144 - 45,710,358+NCBI
Human Genome Assembly Build 361746,597,890 - 46,604,104+NCBI
Human Cytogenetic Map17q21.3 NCBI
Human Genome Assembly1746,598,810 - 46,604,103 NCBI

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)
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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NME2
Entrez Gene
Ensembl Gene
GBrowse: hg18 hg19
JBrowse: hg18 hg19
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1346564
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2015-10-06
Status: ACTIVE