Gene: NME2 (NME/NM23 nucleoside diphosphate kinase 2) Homo sapiens
Symbol: NME2
Name: NME/NM23 nucleoside diphosphate kinase 2
Description: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; histidine protein kinase NDKB; MGC111212; MGC2212; NDK B; NDKB; NDP kinase B; NDPK-B; NDPKB; NM23-H2; NM23B; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; nucleoside diphosphate kinase B; nucleotide diphosphate kinase B; OTTHUMP00000174727; OTTHUMP00000174728; OTTHUMP00000174774; OTTHUMP00000174775; OTTHUMP00000174776; PUF
Related Pseudogenes: NME2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381751,165,435 - 51,171,744 (+)NCBIGRCh38hg38GRCh38
GRCh371749,242,796 - 49,249,105 (+)NCBIGRCh37hg19GRCh37
Build 361746,597,890 - 46,604,104 (+)NCBINCBI36hg18NCBI36
Build 341746,598,810 - 46,604,103NCBI
Celera1745,704,144 - 45,710,358 (+)NCBI
Cytogenetic Map17q21.33NCBImapview
HuRef1744,612,062 - 44,618,375 (+)NCBI
CHM1_11749,307,431 - 49,313,740 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NME2
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1346564
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2017-03-14
Status: ACTIVE